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September 17, 2019 19:26
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Calculating CVD risk for patients
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| var Formula = function (appmodel){ | |
| var self= this; | |
| var debug = false; | |
| self.s010 = function() { | |
| var i; | |
| if (appmodel.Form().isAfrican() && appmodel.Form().isFemale()) i = 0.95334; | |
| if (!appmodel.Form().isAfrican() && appmodel.Form().isFemale()) i = 0.96652; | |
| if (appmodel.Form().isAfrican() && appmodel.Form().isMale()) i = 0.89536; | |
| if (!appmodel.Form().isAfrican() && appmodel.Form().isMale()) i = 0.91436; | |
| return i; | |
| }; | |
| self.mnxb = function() { | |
| var i; | |
| if (appmodel.Form().isAfrican() && appmodel.Form().isFemale()) i = 86.61; | |
| if (!appmodel.Form().isAfrican() && appmodel.Form().isFemale()) i = -29.18; | |
| if (appmodel.Form().isAfrican() && appmodel.Form().isMale()) i = 19.54; | |
| if (!appmodel.Form().isAfrican() && appmodel.Form().isMale()) i = 61.18; | |
| return i; | |
| }; | |
| //Optimal Values using baseline | |
| self.lnage = function() { | |
| if(appmodel.isFollowUp()) | |
| return Math.log(appmodel.Form().BaselineAge()); | |
| else | |
| return Math.log(appmodel.Form().Age()); | |
| }; | |
| self.lnBaseLineUpage = function() { | |
| return Math.log(appmodel.Form().BaselineAge()); | |
| }; | |
| self.lnFollowUpage = function() { | |
| return Math.log(appmodel.Form().Age()); | |
| }; | |
| self.opt_lnhdl = function() { | |
| return Math.log(50); | |
| }; | |
| self.opt_lntot = function() { | |
| return Math.log(170); | |
| }; | |
| self.opt_trlnsbp = function() { | |
| return Math.log(110) * Number(false) | |
| }; | |
| self.opt_ntlnsbp = function() { | |
| return Math.log(110) * Number(!false) | |
| }; | |
| self.opt_age2 = function(isFollowUp) { | |
| if(isFollowUp) | |
| return self.lnFollowUpage() * self.lnFollowUpage(); | |
| else | |
| return self.lnage() * self.lnage(); | |
| }; | |
| self.opt_agetc = function(isFollowUp) { | |
| if(isFollowUp) | |
| return self.opt_lntot() * self.lnFollowUpage(); | |
| else | |
| return self.opt_lntot() * self.lnage(); | |
| }; | |
| self.opt_agehdl = function(isFollowUp) { | |
| if(isFollowUp) | |
| return self.opt_lnhdl() * self.lnFollowUpage(); | |
| else | |
| return self.opt_lnhdl() * self.lnage(); | |
| }; | |
| self.opt_agetsbp = function(isFollowUp) { | |
| if(isFollowUp) | |
| return self.lnFollowUpage() * self.opt_trlnsbp(); | |
| else | |
| return self.lnage() * self.opt_trlnsbp(); | |
| }; | |
| self.opt_agentsbp = function(isFollowUp) { | |
| if(isFollowUp) | |
| return self.lnFollowUpage() * self.opt_ntlnsbp(); | |
| else | |
| return self.lnage() * self.opt_ntlnsbp(); | |
| }; | |
| self.otp_agesmoke = function() { | |
| return self.lnage() * Number(false); | |
| }; | |
| self.opt_agedm = function() { | |
| return self.lnage() * Number(false); | |
| }; | |
| self.optimalPredictCalculate = function(isFollowUp) { | |
| var i; | |
| if (appmodel.Form().isAfrican() && appmodel.Form().isFemale() ) | |
| i = 17.1141 * (isFollowUp ? self.lnFollowUpage(): self.lnage()) + 0.9396 * self.opt_lntot() + (-18.9196 * self.opt_lnhdl()) + 4.4748 * self.opt_agehdl(isFollowUp) + 29.2907 * self.opt_trlnsbp() + (-6.4321 * self.opt_agetsbp(isFollowUp)) + 27.8197 * self.opt_ntlnsbp() + (-6.0873 * self.opt_agentsbp(isFollowUp)) + 0.6908 * Number(false) + 0.8738 * Number(false); | |
| if (!appmodel.Form().isAfrican() && appmodel.Form().isFemale() ) | |
| i = (-29.799 * (isFollowUp ? self.lnFollowUpage(): self.lnage())) + 4.884 * self.opt_age2() + 13.54 * self.opt_lntot() + (-3.114 * self.opt_agetc(isFollowUp)) + (-13.578 * self.opt_lnhdl()) + 3.149 * self.opt_agehdl(isFollowUp) + 2.019 * self.opt_trlnsbp() + 1.957 * self.opt_ntlnsbp() + 7.574 * Number(false) + (-1.665 * self.otp_agesmoke(isFollowUp)) + 0.661 * Number(false); | |
| if (appmodel.Form().isAfrican() && appmodel.Form().isMale()) | |
| i = 2.469 * (isFollowUp ? self.lnFollowUpage(): self.lnage()) + 0.302 * self.opt_lntot() + (-0.307 * self.opt_lnhdl()) + 1.916 * self.opt_trlnsbp() + 1.809 * self.opt_ntlnsbp() + 0.549 * Number(false) + 0.645 * Number(false); | |
| if (!appmodel.Form().isAfrican() && appmodel.Form().isMale()) | |
| i = 12.344 * (isFollowUp ? self.lnFollowUpage(): self.lnage()) + 11.853 * self.opt_lntot() + (-2.664 * self.opt_agetc(isFollowUp)) + (-7.99 * self.opt_lnhdl()) + 1.769 * self.opt_agehdl(isFollowUp) + 1.797 * self.opt_trlnsbp() + 1.764 * self.opt_ntlnsbp() + 7.837 * Number(false) + (-1.795 * self.otp_agesmoke(isFollowUp)) + 0.658 * Number(false); | |
| if(debug) | |
| console.log(i); | |
| return i; | |
| }; | |
| self.optimalCvdPredict = function(isFollowUp) { | |
| var i; | |
| i= (1 - Math.pow(self.s010(), Math.exp( self.optimalPredictCalculate(isFollowUp) - self.mnxb()))); | |
| if (debug) | |
| console.log(i); | |
| return i; | |
| }; | |
| //Sheet(10-Year ASCVD Follow up) OPTIMAL Floor Value derived using the OPTIMAL level - G28 | |
| self.optimalBaselineRisk = function(){ | |
| var i = '~%'; | |
| var predValue = self.optimalCvdPredict(false); | |
| if (predValue != 1 && !isNaN(predValue)) { | |
| var number = predValue * 100 | |
| if (debug) | |
| console.log(number); | |
| i = number.toFixed(1) + '%'; | |
| } | |
| return i; | |
| }; | |
| //Sheet(10-Year ASCVD Follow up) OPTIMAL Floor Value derived UPDATED AGE - G59 | |
| self.optimalFollowUpRisk = function(){ | |
| var i = '~%'; | |
| var predValue = self.optimalCvdPredict(true); | |
| if (predValue != 1 && !isNaN(predValue)) { | |
| var number = predValue * 100 | |
| i = number.toFixed(1) + '%'; | |
| } | |
| return i; | |
| }; | |
| //ASCVD Risk calculation factors | |
| self.lnhdl = function(isCurrent) { | |
| if(isCurrent) | |
| return Math.log(appmodel.Form().HDLCholesterol()); | |
| else | |
| return Math.log(appmodel.Form().BaselineHDLCholesterol()); | |
| }; | |
| self.lntot = function(isCurrent) { | |
| if(isCurrent) | |
| return Math.log(appmodel.Form().TotalCholesterol()); | |
| else | |
| return Math.log(appmodel.Form().BaselineTotalCholesterol()); | |
| }; | |
| self.trlnsbp = function(isCurrent) { | |
| if(isCurrent) | |
| return Math.log(appmodel.Form().BloodPressure()) * Number(appmodel.Form().isHypertension()); | |
| else | |
| return Math.log(appmodel.Form().BaselineBloodPressure()) * Number(appmodel.Form().isBaseLineHypertension()); | |
| }; | |
| self.ntlnsbp = function(isCurrent) { | |
| if(isCurrent) | |
| return Math.log(appmodel.Form().BloodPressure()) * Number(!appmodel.Form().isHypertension()); | |
| else | |
| return Math.log(appmodel.Form().BaselineBloodPressure()) * Number(!appmodel.Form().isBaseLineHypertension()); | |
| }; | |
| self.age2 = function(isCurrent) { | |
| if(isCurrent) | |
| return self.lnFollowUpage() * self.lnFollowUpage(); | |
| else | |
| return self.lnage() * self.lnage(); | |
| }; | |
| self.agetc = function(isCurrent) { | |
| if(isCurrent) | |
| return self.lntot(isCurrent) * self.lnFollowUpage(); | |
| else | |
| return self.lntot() * self.lnage(); | |
| }; | |
| self.agehdl = function(isCurrent) { | |
| if(isCurrent) | |
| return self.lnhdl(isCurrent) * self.lnFollowUpage(); | |
| else | |
| return self.lnhdl() * self.lnage(); | |
| }; | |
| self.agetsbp = function(isCurrent) { | |
| if(isCurrent) | |
| return self.lnFollowUpage() * self.trlnsbp(isCurrent); | |
| else | |
| return self.lnage() * self.trlnsbp(); | |
| }; | |
| self.agentsbp = function(isCurrent) { | |
| if(isCurrent) | |
| return self.lnFollowUpage() * self.ntlnsbp(isCurrent); | |
| else | |
| return self.lnage() * self.ntlnsbp(); | |
| }; | |
| //Need to check smoker case in case of baseline | |
| self.agesmoke = function(isCurrent) { | |
| if(isCurrent) | |
| return self.lnFollowUpage() * Number(appmodel.Form().isSmoker()); | |
| else | |
| return self.lnage() * Number(appmodel.Form().isBaseLineSmoker()); | |
| }; | |
| self.agedm = function(isCurrent) { | |
| if(isCurrent) | |
| return self.lnFollowUpage() * Number(appmodel.Form().isDiabetic()); | |
| else | |
| return self.lnage() * Number(appmodel.Form().isBaseLineDiabetic()); | |
| }; | |
| //Need to check baseline diabetic and smoker values | |
| self.predictCalculate = function(isCurrent) { | |
| var i; | |
| if (appmodel.Form().isAfrican() && appmodel.Form().isFemale() ) | |
| i = 17.1141 * (isCurrent ? self.lnFollowUpage(): self.lnage()) + 0.9396 * self.lntot(isCurrent) + (-18.9196 * self.lnhdl(isCurrent)) + 4.4748 * self.agehdl(isCurrent) + 29.2907 * self.trlnsbp(isCurrent) + (-6.4321 * self.agetsbp(isCurrent)) + 27.8197 * self.ntlnsbp(isCurrent) + (-6.0873 * self.agentsbp(isCurrent)) + 0.6908 * (isCurrent ? Number(appmodel.Form().isSmoker()):Number(appmodel.Form().isBaseLineSmoker())) + 0.8738 * (isCurrent ? Number(appmodel.Form().isDiabetic()):Number(appmodel.Form().isBaseLineDiabetic())) | |
| if (!appmodel.Form().isAfrican() && appmodel.Form().isFemale() ) | |
| i = (-29.799 * (isCurrent ? self.lnFollowUpage(): self.lnage())) + 4.884 * self.age2(isCurrent) + 13.54 * self.lntot(isCurrent) + (-3.114 * self.agetc(isCurrent)) + (-13.578 * self.lnhdl(isCurrent)) + 3.149 * self.agehdl(isCurrent) + 2.019 * self.trlnsbp(isCurrent) + 1.957 * self.ntlnsbp(isCurrent) + 7.574 * (isCurrent ? Number(appmodel.Form().isSmoker()):Number(appmodel.Form().isBaseLineSmoker())) + (-1.665 * self.agesmoke(isCurrent)) + 0.661 * (isCurrent ? Number(appmodel.Form().isDiabetic()):Number(appmodel.Form().isBaseLineDiabetic())); | |
| if (appmodel.Form().isAfrican() && appmodel.Form().isMale()) | |
| i = 2.469 * (isCurrent ? self.lnFollowUpage(): self.lnage()) + 0.302 * self.lntot(isCurrent) + (-0.307 * self.lnhdl(isCurrent)) + 1.916 * self.trlnsbp(isCurrent) + 1.809 * self.ntlnsbp(isCurrent) + 0.549 * (isCurrent ? Number(appmodel.Form().isSmoker()):Number(appmodel.Form().isBaseLineSmoker())) + 0.645 * (isCurrent ? Number(appmodel.Form().isDiabetic()):Number(appmodel.Form().isBaseLineDiabetic())); | |
| if (!appmodel.Form().isAfrican() && appmodel.Form().isMale()) | |
| i = 12.344 * (isCurrent ? self.lnFollowUpage(): self.lnage()) + 11.853 * self.lntot(isCurrent) + (-2.664 * self.agetc(isCurrent)) + (-7.99 * self.lnhdl(isCurrent)) + 1.769 * self.agehdl(isCurrent) + 1.797 * self.trlnsbp(isCurrent) + 1.764 * self.ntlnsbp(isCurrent) + 7.837 * (isCurrent ? Number(appmodel.Form().isSmoker()):Number(appmodel.Form().isBaseLineSmoker())) + (-1.795 * self.agesmoke(isCurrent)) + 0.658 * (isCurrent ? Number(appmodel.Form().isDiabetic()):Number(appmodel.Form().isBaseLineDiabetic())); | |
| if(debug) | |
| console.log(i); | |
| return i; | |
| }; | |
| //updated estimates trlnsbp and ntlnsbp | |
| self.up_trlnsbp = function() { | |
| return Math.log(appmodel.Form().BaselineBloodPressure()) * Number(appmodel.Form().isHypertension()); | |
| }; | |
| self.up_ntlnsbp = function() { | |
| return Math.log(appmodel.Form().BaselineBloodPressure()) * Number(!appmodel.Form().isHypertension()); | |
| }; | |
| self.up_agetsbp = function() { | |
| return self.lnFollowUpage() * self.up_trlnsbp(); | |
| }; | |
| //This takes only updated age and use baseline values and Need to check isDiabetic | |
| self.updatedPredictCalculate = function() { | |
| var i; | |
| if (appmodel.Form().isAfrican() && appmodel.Form().isFemale() ) { | |
| i = 17.1141 * self.lnFollowUpage() + 0.9396 * self.lntot(false) + (-18.9196 * self.lnhdl(false)) + 4.4748 * (Math.log(appmodel.Form().BaselineHDLCholesterol()) * self.lnFollowUpage()) + 29.2907 * self.up_trlnsbp() + (-6.4321 * self.up_agetsbp()) + 27.8197 * self.up_ntlnsbp() + (-6.0873 * (self.up_ntlnsbp() * self.lnFollowUpage())) + 0.6908 * Number(appmodel.Form().isSmoker()) + 0.8738 * Number(appmodel.Form().isDiabetic()); | |
| } | |
| if (!appmodel.Form().isAfrican() && appmodel.Form().isFemale() ) | |
| i = (-29.799 * self.lnFollowUpage()) + 4.884 * self.age2(true) + 13.54 * self.lntot(false) + (-3.114 * (self.lntot(false) * self.lnFollowUpage())) + (-13.578 * self.lnhdl(false)) + 3.149 * (self.lnhdl(false) * self.lnFollowUpage()) + 2.019 * self.up_trlnsbp() + 1.957 * self.up_ntlnsbp() + 7.574 * Number(appmodel.Form().isSmoker()) + (-1.665 * (self.lnFollowUpage() * Number(appmodel.Form().isSmoker()))) + 0.661 * Number(appmodel.Form().isDiabetic()); | |
| if (appmodel.Form().isAfrican() && appmodel.Form().isMale()) | |
| i = 2.469 * self.lnFollowUpage() + 0.302 * self.lntot(false) + (-0.307 * self.lnhdl(false)) + 1.916 * self.up_trlnsbp() + 1.809 * self.up_ntlnsbp() + 0.549 * Number(appmodel.Form().isSmoker()) + 0.645 * Number(appmodel.Form().isDiabetic()); | |
| if (!appmodel.Form().isAfrican() && appmodel.Form().isMale()) | |
| i = 12.344 * self.lnFollowUpage() + 11.853 * self.lntot(false) + (-2.664 * (self.lntot(false) * self.lnFollowUpage())) + (-7.99 * self.lnhdl(false)) + 1.769 * (self.lnhdl(false) * self.lnFollowUpage()) + 1.797 * self.up_trlnsbp() + 1.764 * self.up_ntlnsbp() + 7.837 * Number(appmodel.Form().isSmoker()) + (-1.795 * (self.lnFollowUpage() * Number(appmodel.Form().isSmoker()))) + 0.658 * Number(appmodel.Form().isDiabetic()); | |
| if(debug) | |
| console.log(i); | |
| return i; | |
| }; | |
| //Calculates CVD predict for baseline and current values | |
| self.cvdPredict = function(isCurrent) { | |
| var i; | |
| i= (1 - Math.pow(self.s010(), Math.exp( self.predictCalculate(isCurrent) - self.mnxb()))); | |
| if(debug) | |
| console.log(i); | |
| return i; | |
| }; | |
| //Sheet(10-Year Expected ASCVD) 10-Year ASCVD Risk at Baseline - G29 | |
| self.TenYearBaselineRisk = function(){ | |
| var i = '~%'; | |
| var predValue = self.cvdPredict(false); | |
| if (predValue != 1 && !isNaN(predValue)) { | |
| var number = predValue * 100 | |
| if(debug) | |
| console.log(number); | |
| i = number.toFixed(1) + '%'; | |
| } | |
| return i; | |
| }; | |
| //Sheet(10-Year ASCVD Follow up) 10-Year ASCVD floor for follow up - G92 | |
| self.TenYearRiskUsingFollowUpValue = function(){ | |
| var i = '~%'; | |
| var predValue = self.cvdPredict(true); | |
| if (predValue != 1 && !isNaN(predValue)) { | |
| var number = predValue * 100 | |
| i = number.toFixed(1) + '%'; | |
| } | |
| return i; | |
| }; | |
| self.updatedCvdPredict = function() { | |
| var i; | |
| i= (1 - Math.pow(self.s010(), Math.exp( self.updatedPredictCalculate() - self.mnxb()))); | |
| if(debug) | |
| console.log("e125 => ",i, " s010 => ",self.s010(), " mnxb => ",self.mnxb(), " d125 => ", self.updatedPredictCalculate()); | |
| return i; | |
| }; | |
| //Sheet(10-Year ASCVD Follow up) Updated Estimates - G125 | |
| self.TenYearRiskUsingUpdatedEstimates = function(){ | |
| var i = '~%'; | |
| var predValue = self.updatedCvdPredict(); | |
| if (predValue != 1 && !isNaN(predValue)) { | |
| var number = predValue * 100 | |
| i = number.toFixed(1) + '%'; | |
| } | |
| return i; | |
| }; | |
| // Relative Risk calculations | |
| self.relativeRiskStatin = 0.75; | |
| self.relativeRiskBP = Math.exp((Math.log(0.84) + Math.log(0.64))/2); | |
| self.relativeRiskStopSmoking=0.73; | |
| self.relativeRiskAspirin = 0.90; | |
| self.relativeRiskAspirinStatin = (self.relativeRiskStatin * self.relativeRiskAspirin); | |
| self.relativeRiskAspirinBP = (self.relativeRiskBP * self.relativeRiskAspirin); | |
| self.relativeRiskStatinBP = (self.relativeRiskStatin * self.relativeRiskBP); | |
| self.relativeRiskStatinStopSmoking = (self.relativeRiskStatin * self.relativeRiskStopSmoking); | |
| self.relativeRiskAspirinStopSmoking = (self.relativeRiskAspirin * self.relativeRiskStopSmoking); | |
| self.relativeRiskBPStopSmoking = (Math.exp((Math.log(0.84) + Math.log(0.64))/2) * 0.73); | |
| self.relativeRiskStatinAspirinBP = (self.relativeRiskStatin * self.relativeRiskBP * self.relativeRiskAspirin); | |
| self.relativeRiskAspirinBPStopSmoking = (self.relativeRiskBP * self.relativeRiskStopSmoking * self.relativeRiskAspirin); | |
| self.relativeRiskStatinBPStopSmoking = (self.relativeRiskBP * self.relativeRiskStopSmoking * self.relativeRiskStatin); | |
| self.relativeRiskAspirinStatinStopSmoking = (self.relativeRiskAspirin * self.relativeRiskStopSmoking * self.relativeRiskStatin); | |
| self.relativeRiskAll4 = (self.relativeRiskStatin * self.relativeRiskAspirin * self.relativeRiskStopSmoking * self.relativeRiskBP); | |
| self.relativeRiskFollowupBP = Math.exp((Math.log(0.79) + Math.log(0.54))/2).toFixed(2); | |
| //Delta Calculations | |
| self.statinDelta = function(){ | |
| if(appmodel.Form().LDLCholesterol()){ | |
| return Math.pow(self.relativeRiskStatin,((appmodel.Form().BaselineLDLCholesterol() - appmodel.Form().LDLCholesterol())/38.7)); | |
| } | |
| }; | |
| self.bloodPresureDelta = function(){ | |
| if(appmodel.Form().BloodPressure()){ | |
| return Math.pow( Math.exp((Math.log(0.79) + Math.log(0.54))/2),((appmodel.Form().BaselineBloodPressure() - appmodel.Form().BloodPressure())/10)); | |
| } | |
| }; | |
| self.smokerDelta = function(){ | |
| if(!appmodel.Form().isBaseLineSmoker() || !appmodel.Form().QuiteSmokingMonths()){ | |
| return 1; | |
| }else if(appmodel.Form().QuiteSmokingMonths()){ | |
| return appmodel.Form().QuiteSmokingMonths().value; | |
| } | |
| else { | |
| return 1; | |
| } | |
| }; | |
| self.aspirinDelta = function(){ | |
| if(appmodel.Form().OnAspirin() == 'Yes'){ | |
| return 0.9; | |
| }else{ | |
| return 1; | |
| } | |
| }; | |
| //Sheet(10-Year ASCVD Follow up) all therapy delta - G119 | |
| self.summationDelta = function(){ | |
| return self.statinDelta() * self.bloodPresureDelta() * self.smokerDelta() * self.aspirinDelta(); | |
| }; | |
| //Sheet(10-Year ASCVD Follow up) 10-Year ASCVD with delta and updated estimates - H125 | |
| self.TenYearRiskWithUpdatedEstimatesDelta = function(){ | |
| var g125 = self.updatedCvdPredict(); | |
| var g119 = self.summationDelta(); | |
| if(debug) | |
| console.log("g125 => ", g125," g119 => ",g119); | |
| return g125 * g119; | |
| //return self.updatedCvdPredict() * self.summationDelta(); | |
| }; | |
| //Sheet(Updated RR) 10-Year ASCVD follow up - C19 | |
| self.TenYearFollowUpRisk = function(){ | |
| var h125 = self.TenYearRiskWithUpdatedEstimatesDelta(); | |
| var g59 = self.optimalCvdPredict(true); | |
| var g92 = self.cvdPredict(true); | |
| var number = Math.min(Math.max(h125,g59), g92) * 100; | |
| return number.toFixed(1) + '%'; | |
| }; | |
| //start: Forecasted Risk at Initial Visit(Expected RR sheet) | |
| self.ForecastRiskStatin = function(){ | |
| var baselineRisk = appmodel.isFollowUp() ? self.cvdPredict(false) :self.cvdPredict(true); | |
| var optimalBaseline = self.optimalCvdPredict(false); | |
| if(baselineRisk < 0.05){ | |
| return 'NA'; | |
| }else{ | |
| return Math.max(baselineRisk * self.relativeRiskStatin, optimalBaseline); | |
| } | |
| }; | |
| self.ForecastRiskBP = function(){ | |
| var baselineRisk = appmodel.isFollowUp() ? self.cvdPredict(false) :self.cvdPredict(true); | |
| var optimalBaseline = self.optimalCvdPredict(false); | |
| var bp = appmodel.isFollowUp() ? appmodel.Form().BaselineBloodPressure() : appmodel.Form().BloodPressure(); | |
| var diabetic = appmodel.isFollowUp() ? appmodel.Form().BaselineDiabetic() : appmodel.Form().Diabetic(); | |
| if(bp < 120 || (diabetic == 'Yes' && bp < 130)){ | |
| return 'NA'; | |
| }else{ | |
| return Math.max(baselineRisk * self.relativeRiskBP, optimalBaseline); | |
| } | |
| }; | |
| self.ForecastRiskSmoking = function(){ | |
| var baselineRisk = appmodel.isFollowUp() ? self.cvdPredict(false) : self.cvdPredict(true); | |
| var optimalBaseline = self.optimalCvdPredict(false); | |
| var smoke = appmodel.isFollowUp() ? appmodel.Form().BaselineSmoker() : appmodel.Form().Smoker(); | |
| if(smoke == 'No' || smoke == 'Never'){ | |
| return 'NA'; | |
| }else{ | |
| return Math.max(baselineRisk * self.relativeRiskStopSmoking, optimalBaseline); | |
| } | |
| }; | |
| self.ForecastRiskAspirin = function(){ | |
| var baselineRisk = appmodel.isFollowUp() ? self.cvdPredict(false) : self.cvdPredict(true); | |
| var optimalBaseline = self.optimalCvdPredict(false); | |
| if(baselineRisk < 0.1){ | |
| return 'NA'; | |
| }else{ | |
| return Math.max(baselineRisk * self.relativeRiskAspirin, optimalBaseline); | |
| } | |
| }; | |
| self.ForecastRiskAspirinStatin = function(){ | |
| var baselineRisk = appmodel.isFollowUp() ? self.cvdPredict(false) : self.cvdPredict(true); | |
| var optimalBaseline = self.optimalCvdPredict(false); | |
| if(baselineRisk < 0.1){ | |
| return 'NA'; | |
| }else{ | |
| return Math.max(baselineRisk * self.relativeRiskAspirinStatin, optimalBaseline); | |
| } | |
| }; | |
| self.ForecastRiskAspirinBP = function(){ | |
| var baselineRisk = appmodel.isFollowUp() ? self.cvdPredict(false) : self.cvdPredict(true); | |
| var optimalBaseline = self.optimalCvdPredict(false); | |
| var bp = appmodel.isFollowUp() ? appmodel.Form().BaselineBloodPressure() : appmodel.Form().BloodPressure(); | |
| var diabetic = appmodel.isFollowUp() ? appmodel.Form().BaselineDiabetic() : appmodel.Form().Diabetic(); | |
| if(baselineRisk < 0.1 || (bp < 120 || (diabetic == 'Yes' && bp < 130))){ | |
| return 'NA'; | |
| }else{ | |
| return Math.max(baselineRisk * self.relativeRiskAspirinBP, optimalBaseline); | |
| } | |
| }; | |
| self.ForecastRiskStatinBP = function(){ | |
| var baselineRisk = appmodel.isFollowUp() ? self.cvdPredict(false) : self.cvdPredict(true); | |
| var optimalBaseline = self.optimalCvdPredict(false); | |
| var bp = appmodel.isFollowUp() ? appmodel.Form().BaselineBloodPressure() : appmodel.Form().BloodPressure(); | |
| var diabetic = appmodel.isFollowUp() ? appmodel.Form().BaselineDiabetic() : appmodel.Form().Diabetic(); | |
| if(baselineRisk < 0.05 || (bp < 120 || (diabetic == 'Yes' && bp < 130))){ | |
| return 'NA'; | |
| }else{ | |
| return Math.max(baselineRisk * self.relativeRiskStatinBP, optimalBaseline); | |
| } | |
| }; | |
| self.ForecastRiskStatinSmoking = function(){ | |
| var baselineRisk = appmodel.isFollowUp() ? self.cvdPredict(false) : self.cvdPredict(true); | |
| var optimalBaseline = self.optimalCvdPredict(false); | |
| var smoke = appmodel.isFollowUp() ? appmodel.Form().BaselineSmoker() : appmodel.Form().Smoker(); | |
| if(baselineRisk < 0.05 || smoke == 'No' || smoke == 'Never'){ | |
| return 'NA'; | |
| }else{ | |
| return Math.max(baselineRisk * self.relativeRiskStatinStopSmoking, optimalBaseline); | |
| } | |
| }; | |
| self.ForecastRiskAspirinSmoking = function(){ | |
| var baselineRisk = appmodel.isFollowUp() ? self.cvdPredict(false) : self.cvdPredict(true); | |
| var optimalBaseline = self.optimalCvdPredict(false); | |
| var smoke = appmodel.isFollowUp() ? appmodel.Form().BaselineSmoker() : appmodel.Form().Smoker(); | |
| if(baselineRisk < 0.1 || smoke == 'No' || smoke == 'Never'){ | |
| return 'NA'; | |
| }else{ | |
| return Math.max(baselineRisk * self.relativeRiskAspirinStopSmoking, optimalBaseline); | |
| } | |
| }; | |
| self.ForecastRiskBPSmoking = function(){ | |
| var baselineRisk = appmodel.isFollowUp() ? self.cvdPredict(false) : self.cvdPredict(true); | |
| var optimalBaseline = self.optimalCvdPredict(false); | |
| var smoke = appmodel.isFollowUp() ? appmodel.Form().BaselineSmoker() : appmodel.Form().Smoker(); | |
| var bp = appmodel.isFollowUp() ? appmodel.Form().BaselineBloodPressure() : appmodel.Form().BloodPressure(); | |
| var diabetic = appmodel.isFollowUp() ? appmodel.Form().BaselineDiabetic() : appmodel.Form().Diabetic(); | |
| if((bp < 120 || smoke == 'No' || smoke == 'Never') || (diabetic == 'Yes' && bp < 130)) { | |
| return 'NA'; | |
| }else{ | |
| return Math.max(baselineRisk * self.relativeRiskBPStopSmoking, optimalBaseline); | |
| } | |
| }; | |
| self.ForecastRiskAspirinStatinBP = function(){ | |
| var baselineRisk = appmodel.isFollowUp() ? self.cvdPredict(false) : self.cvdPredict(true); | |
| var optimalBaseline = self.optimalCvdPredict(false); | |
| var bp = appmodel.isFollowUp() ? appmodel.Form().BaselineBloodPressure() : appmodel.Form().BloodPressure(); | |
| var diabetic = appmodel.isFollowUp() ? appmodel.Form().BaselineDiabetic() : appmodel.Form().Diabetic(); | |
| if(baselineRisk < 0.1 || (bp < 120 || (diabetic == 'Yes' && bp < 130))){ | |
| return 'NA'; | |
| }else{ | |
| return Math.max(baselineRisk * self.relativeRiskStatinAspirinBP, optimalBaseline); | |
| } | |
| }; | |
| self.ForecastRiskAspirinBPSmoking = function(){ | |
| var baselineRisk = appmodel.isFollowUp() ? self.cvdPredict(false) : self.cvdPredict(true); | |
| var optimalBaseline = self.optimalCvdPredict(false); | |
| var smoke = appmodel.isFollowUp() ? appmodel.Form().BaselineSmoker() : appmodel.Form().Smoker(); | |
| var bp = appmodel.isFollowUp() ? appmodel.Form().BaselineBloodPressure() : appmodel.Form().BloodPressure(); | |
| var diabetic = appmodel.isFollowUp() ? appmodel.Form().BaselineDiabetic() : appmodel.Form().Diabetic(); | |
| if(baselineRisk < 0.1 || (bp < 120 || smoke == 'No' || smoke == 'Never') || (diabetic == 'Yes' && bp < 130)) { | |
| return 'NA'; | |
| }else{ | |
| return Math.max(baselineRisk * self.relativeRiskAspirinBPStopSmoking, optimalBaseline); | |
| } | |
| }; | |
| self.ForecastRiskStatinBPSmoking = function(){ | |
| var baselineRisk = appmodel.isFollowUp() ? self.cvdPredict(false) : self.cvdPredict(true); | |
| var optimalBaseline = self.optimalCvdPredict(false); | |
| var smoke = appmodel.isFollowUp() ? appmodel.Form().BaselineSmoker() : appmodel.Form().Smoker(); | |
| var bp = appmodel.isFollowUp() ? appmodel.Form().BaselineBloodPressure() : appmodel.Form().BloodPressure(); | |
| var diabetic = appmodel.isFollowUp() ? appmodel.Form().BaselineDiabetic() : appmodel.Form().Diabetic(); | |
| if(baselineRisk < 0.05 || (bp < 120 || smoke == 'No' || smoke == 'Never') || (diabetic == 'Yes' && bp < 130)) { | |
| return 'NA'; | |
| }else{ | |
| return Math.max(baselineRisk * self.relativeRiskStatinBPStopSmoking, optimalBaseline); | |
| } | |
| }; | |
| self.ForecastRiskAspirinStatinSmoking = function(){ | |
| var baselineRisk = appmodel.isFollowUp() ? self.cvdPredict(false) : self.cvdPredict(true); | |
| var optimalBaseline = self.optimalCvdPredict(false); | |
| var smoke = appmodel.isFollowUp() ? appmodel.Form().BaselineSmoker() : appmodel.Form().Smoker(); | |
| if(baselineRisk < 0.1 || smoke == 'No' || smoke == 'Never'){ | |
| return 'NA'; | |
| }else{ | |
| return Math.max(baselineRisk * self.relativeRiskAspirinStatinStopSmoking, optimalBaseline); | |
| } | |
| }; | |
| self.ForecastRiskSartAll4 = function(){ | |
| var baselineRisk = appmodel.isFollowUp() ? self.cvdPredict(false) : self.cvdPredict(true); | |
| var optimalBaseline = self.optimalCvdPredict(false); | |
| var smoke = appmodel.isFollowUp() ? appmodel.Form().BaselineSmoker() : appmodel.Form().Smoker(); | |
| var bp = appmodel.isFollowUp() ? appmodel.Form().BaselineBloodPressure() : appmodel.Form().BloodPressure(); | |
| var diabetic = appmodel.isFollowUp() ? appmodel.Form().BaselineDiabetic() : appmodel.Form().Diabetic(); | |
| if(baselineRisk < 0.1 || (bp < 120 || smoke == 'No' || smoke == 'Never') || (diabetic == 'Yes' && bp < 130)) { | |
| return 'NA'; | |
| }else{ | |
| return Math.max(baselineRisk * self.relativeRiskAll4, optimalBaseline); | |
| } | |
| }; | |
| //end: Forecasted Risk at Initial Visit | |
| //start: Forecasted Risk at Follow Up Visit | |
| self.forecasttrlnsbp = function(value) { | |
| return Math.log(appmodel.Form().BloodPressure()) * Number(value); | |
| }; | |
| self.forecastntlnsbp = function(value) { | |
| return Math.log(appmodel.Form().BloodPressure()) * Number(!value); | |
| }; | |
| self.forecastagetsbp = function(value) { | |
| return self.lnFollowUpage() * self.forecasttrlnsbp(value); | |
| }; | |
| self.forecastagentsbp = function(value) { | |
| return self.lnFollowUpage() * self.forecastntlnsbp(value); | |
| }; | |
| self.forecastagesmoke = function(value) { | |
| return self.lnFollowUpage() * Number(value); | |
| }; | |
| self.forecastAspirinDelta = function(value){ | |
| if(value){ | |
| return 0.9; | |
| }else{ | |
| return 1; | |
| } | |
| }; | |
| //Need to check baseline diabetic and smoker values | |
| self.forecastPredictCalculate = function(isCurrent, bpValue, smokerValue) { | |
| var i; | |
| if (appmodel.Form().isAfrican() && appmodel.Form().isFemale() ) | |
| i = 17.1141 * (isCurrent ? self.lnFollowUpage(): self.lnage()) + 0.9396 * self.lntot(isCurrent) + (-18.9196 * self.lnhdl(isCurrent)) + 4.4748 * self.agehdl(isCurrent) + 29.2907 * self.forecasttrlnsbp(bpValue) + (-6.4321 * self.forecastagetsbp(bpValue)) + 27.8197 * self.forecastntlnsbp(bpValue) + (-6.0873 * self.forecastagentsbp(bpValue)) + 0.6908 * ( Number(smokerValue)) + 0.8738 * (isCurrent ? Number(appmodel.Form().isDiabetic()):Number(appmodel.Form().isBaseLineDiabetic())); | |
| if (!appmodel.Form().isAfrican() && appmodel.Form().isFemale() ) | |
| i = (-29.799 * (isCurrent ? self.lnFollowUpage(): self.lnage())) + 4.884 * self.age2(isCurrent) + 13.54 * self.lntot(isCurrent) + (-3.114 * self.agetc(isCurrent)) + (-13.578 * self.lnhdl(isCurrent)) + 3.149 * self.agehdl(isCurrent) + 2.019 * self.forecasttrlnsbp(bpValue) + 1.957 * self.forecastntlnsbp(bpValue) + 7.574 * (Number(smokerValue)) + (-1.665 * self.forecastagesmoke(smokerValue)) + 0.661 * (isCurrent ? Number(appmodel.Form().isDiabetic()):Number(appmodel.Form().isBaseLineDiabetic())); | |
| if (appmodel.Form().isAfrican() && appmodel.Form().isMale()) | |
| i = 2.469 * (isCurrent ? self.lnFollowUpage(): self.lnage()) + 0.302 * self.lntot(isCurrent) + (-0.307 * self.lnhdl(isCurrent)) + 1.916 * self.forecasttrlnsbp(bpValue) + 1.809 * self.forecastntlnsbp(bpValue) + 0.549 * (Number(smokerValue)) + 0.645 * (isCurrent ? Number(appmodel.Form().isDiabetic()):Number(appmodel.Form().isBaseLineDiabetic())); | |
| if (!appmodel.Form().isAfrican() && appmodel.Form().isMale()) | |
| i = 12.344 * (isCurrent ? self.lnFollowUpage() : self.lnage()) + 11.853 * self.lntot(isCurrent) + (-2.664 * self.agetc(isCurrent)) + (-7.99 * self.lnhdl(isCurrent)) + 1.769 * self.agehdl(isCurrent) + 1.797 * self.forecasttrlnsbp(bpValue) + 1.764 * self.forecastntlnsbp(bpValue) + 7.837 * (Number(smokerValue)) + (-1.795 * self.forecastagesmoke(smokerValue)) + 0.658 * (isCurrent ? Number(appmodel.Form().isDiabetic()) : Number(appmodel.Form().isBaseLineDiabetic())); | |
| return i; | |
| }; | |
| self.forecastCvdPredict = function(isCurrent,bpValue,smokerValue){ | |
| var i; | |
| i= (1 - Math.pow(self.s010(), Math.exp(self.forecastPredictCalculate(isCurrent,bpValue,smokerValue) - self.mnxb()))); | |
| return i; | |
| }; | |
| //Forecasted updated Estimates | |
| self.forecastup_trlnsbp = function(value) { | |
| return Math.log(appmodel.Form().BaselineBloodPressure()) * Number(value); | |
| }; | |
| self.forecastup_ntlnsbp = function(value) { | |
| return Math.log(appmodel.Form().BaselineBloodPressure()) * Number(!value); | |
| }; | |
| self.forecastup_agetsbp = function(value) { | |
| return self.lnFollowUpage() * self.forecastup_trlnsbp(value); | |
| }; | |
| //This takes only updated age,bp and smoker and use baseline values | |
| self.forecastUpdatedPredictCalculate = function(bpValue,smokerValue) { | |
| var i; | |
| if (appmodel.Form().isAfrican() && appmodel.Form().isFemale() ) | |
| i = 17.1141 * self.lnFollowUpage() + 0.9396 * self.lntot(false) + (-18.9196 * self.lnhdl(false)) + 4.4748 * self.agehdl(false) + 29.2907 * self.forecastup_trlnsbp(bpValue) + (-6.4321 * self.forecastup_agetsbp(bpValue)) + 27.8197 * self.forecastup_ntlnsbp(bpValue) + (-6.0873 * (self.forecastup_ntlnsbp(bpValue) * self.lnFollowUpage())) + 0.6908 * Number(smokerValue) + 0.8738 * Number(appmodel.Form().isDiabetic()); | |
| if (!appmodel.Form().isAfrican() && appmodel.Form().isFemale() ) | |
| i = (-29.799 * self.lnFollowUpage()) + 4.884 * self.age2(true) + 13.54 * self.lntot(false) + (-3.114 * (self.lntot(false) * self.lnFollowUpage())) + (-13.578 * self.lnhdl(false)) + 3.149 * (self.lnhdl(false) * self.lnFollowUpage()) + 2.019 * self.forecastup_trlnsbp(bpValue) + 1.957 * self.forecastup_ntlnsbp(bpValue) + 7.574 * Number(smokerValue) + (-1.665 * (self.lnFollowUpage() * Number(smokerValue))) + 0.661 * Number(appmodel.Form().isDiabetic()); | |
| if (appmodel.Form().isAfrican() && appmodel.Form().isMale()) | |
| i = 2.469 * self.lnFollowUpage() + 0.302 * self.lntot(false) + (-0.307 * self.lnhdl(false)) + 1.916 * self.forecastup_trlnsbp(bpValue) + 1.809 * self.forecastup_ntlnsbp(bpValue) + 0.549 * Number(smokerValue) + 0.645 * Number(appmodel.Form().isDiabetic()); | |
| if (!appmodel.Form().isAfrican() && appmodel.Form().isMale()) | |
| i = 12.344 * self.lnFollowUpage() + 11.853 * self.lntot(false) + (-2.664 * (self.lntot(false) * self.lnFollowUpage())) + (-7.99 * self.lnhdl(false)) + 1.769 * (self.lnhdl(false) * self.lnFollowUpage()) + 1.797 * self.forecastup_trlnsbp(bpValue) + 1.764 * self.forecastup_ntlnsbp(bpValue) + 7.837 * Number(smokerValue) + (-1.795 * (self.lnFollowUpage() * Number(smokerValue))) + 0.658 * Number(appmodel.Form().isDiabetic()); | |
| if(debug) | |
| console.log(i); | |
| return i; | |
| }; | |
| self.forecastupdatedCvdPredict = function(bpValue,smokerValue) { | |
| var i; | |
| i= (1 - Math.pow(self.s010(), Math.exp( self.forecastUpdatedPredictCalculate(bpValue,smokerValue) - self.mnxb()))); | |
| if(debug) | |
| console.log(i); | |
| return i; | |
| }; | |
| self.TenYearForecastedFollowUpRisk = function(isSmoker,isBP,isAspirin){ | |
| var h125 = self.forecastupdatedCvdPredict(isBP,isSmoker) * (self.statinDelta() * self.bloodPresureDelta() * self.smokerDelta() * self.forecastAspirinDelta(isAspirin)); | |
| var g59 = self.optimalCvdPredict(true); | |
| var g92 = self.forecastCvdPredict(true,isBP,isSmoker); | |
| var number = Math.min(Math.max(h125,g59), g92) * 100 | |
| return number.toFixed(1) + '%'; | |
| }; | |
| } |
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