NotMatchAny.ps1

function NotMatchAny {
    param(
        [Parameter(Mandatory)]
        [string[]]$Excludes,

        [string]$Property,

        [switch]$First,

        [switch]$Last
    )

    $WordList = $Excludes.ForEach({[regex]::Escape($_)}) -join '|'
    $Pattern  = '(?:{0})' -f $WordList

    if($First){
        $Pattern = '^{0}' -f $Pattern
    }

    if($Last){
        $Pattern = '{0}$' -f $Pattern
    }

    return $(if($Property){
        { $_.$Property -notmatch $Pattern }
    } else {
        { $_ -notmatch $Pattern }
    }).GetNewClosure()
}

$Excludes = 'atl','na','mdm','aus','okc','ssc','ga1','ok1','fns','acs'
$Words    = 'mdm','opw','erp','atl','ssa'
$Words | ? (NotMatchAny $Excludes -First)

$Objects = $Words.ForEach({New-Object psobject -Property @{P=$_}})
$Objects | ? (NotMatchAny $Excludes P -First)

SlowButTerse.ps1

function NotMatchAny {
    param([string[]]$Excludes)
    return { $_ -notmatch "($($Excludes.ForEach({[regex]::Escape($_)}) -join '|'))" }.GetNewClosure()
}