se7.py

s1={1,2,3,4,5}
s2={4,5,6,7,8}
#difference using operator - 
s3=s1-s2
print (s3) #Output: {1,2,3}
s4=s1.difference(s2)
print (s4) #Output: {1,2,3}

#difference_update() will modify the original set. Return type is None.
s1.difference_update(s2)
print (s1) #Output: {1,2,3}
# difference_update by using -= operator
s2-=(s1)
print (s2) #Output: {4,5,6,7,8}