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August 13, 2016 22:55
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Central Dogma of Molecular Biology (https://vimeo.com/178754362)
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# https://vimeo.com/178754362 | |
# Central Dogma of Molecular Biology | |
# DNA --transcription--> RNA --translation--> proteins (which give us traits... and other stuff :) | |
# DNA is an arbitrarily long sequence of 4 molecules | |
# whose initials whose initials are A, T, G, and C | |
# A pairs with T | |
# C pairs with G | |
A = 'A' # => "A" | |
T = 'T' # => "T" | |
G = 'G' # => "G" | |
C = 'C' # => "C" | |
# RNA is an arbitrarily long sequence of 4 molecules | |
# whose initials whose initials are A, U, G, and C | |
U = 'U' | |
# Transcription maps DNA into RNA via a protein named "RNA Polymerase" | |
def transcribe(dna) | |
dna.map do |nucleotide| | |
case nucleotide | |
when 'A' then 'A' | |
when 'T' then 'U' | |
when 'C' then 'C' | |
when 'G' then 'G' | |
end | |
end | |
end | |
dna = [T, C, A, G, G, T] # => ["T", "C", "A", "G", "G", "T"] | |
rna = transcribe dna # => ["U", "C", "A", "G", "G", "U"] | |
# Translation maps every 3 RNA nucleotides into an amino acid | |
# and that "array" of amino acids is what makes a protein | |
# The 3 RNA nucleotides are called a "codon" | |
def translation(rna) | |
rna.each_slice(3).map do |codon| | |
if codon == ["U", "C", "A"] | |
'Serine' | |
elsif codon == ["G", "G", "U"] | |
'Glycine' | |
else raise codon.inspect | |
end | |
end | |
end | |
amino_acids = translation rna # => ["Serine", "Glycine"] | |
# Finally, the amino acids "fold" up based on chemistry | |
# that folded up amino acid strand is our protein |
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