// For complete examples and data files, please go to https://github.com/aspose-cells/Aspose.Cells-for-.NET
// Accessing first worksheet of the Grid
Worksheet sheet = gridDesktop1.Worksheets[0];

if (sheet.Comments[3, 1] != null)
{
    // Removing comment from "c3" cell
    sheet.Comments.Remove(3, 1);
    MessageBox.Show("Comment has been removed");
}
else
{
    MessageBox.Show("Please add comment before removing it.");
}