Example of how to upload a directory hierarchy into a Synapse project

recursive_upload.py

import synapseclient
from synapseclient import Synapse, File, Folder, Project
import os

def upload_recursive(directory, parent):
    for item in os.listdir(directory):
        if os.path.isdir(os.path.join(directory,item)):
            print "%s/" % os.path.basename(item)
            folder = syn.store(Folder(os.path.basename(item), parent=parent))
            upload_recursive(directory=os.path.join(directory, item), parent=folder)
        else:
            print os.path.basename(item)
            file1 = syn.store(File(os.path.join(directory,item), parent=parent))

syn = Synapse()
syn.login()

## insert the ID for your project here:
my_project = 'syn2358458'

parent = syn.get(my_project)
upload_recursive('.', parent)