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Top 50 up and 50 down-regulated genes during OPC differentiation from Dugas et al (https://doi.org/10.1523/jneurosci.2572-06.2006) mapped to human orthologs.
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probeset | fold_change | dugas_symbol | dugas_name | platform | ensembl_id | hgnc_id | hgnc_symbol | hgnc_id_manual | hgnc_symbol_manual | |
---|---|---|---|---|---|---|---|---|---|---|
D28111_g_at | 119.43 | MOBP | Myelin-assoc OL basic protein | HGNC:7189 | MOBP | |||||
K00512_at | 98.36 | MBP | Myelin basic protein | affy_rg_u34a | ENSRNOG00000016516 | HGNC:6925 | MBP | HGNC:6925 | MBP | |
M99485_at | 97.68 | MOG | Myelin oligodendrocyte glycoprotein | affy_rg_u34a | ENSRNOG00000000775 | HGNC:7197 | MOG | HGNC:7197 | MOG | |
rc_AI233181_at | 93.05 | ESTs, no homologies found | ||||||||
rc_AI072770_s_at | 77.71 | PLP | Proteolipid protein | affy_rg_u34a | ENSRNOG00000002419 | HGNC:9086 | PLP1 | HGNC:9086 | PLP1 | |
X55572_at | 71.01 | APOD | Apolipoprotein D | affy_rg_u34a | ENSRNOG00000048273 | HGNC:612 | APOD | HGNC:612 | APOD | |
rc_AA891719_at | 66.72 | ENPP6 | Ectonuc. pyrophos./phosphodiesterase 6 | affy_rg_u34a | ENSRNOG00000009660 | HGNC:23409 | ENPP6 | HGNC:23409 | ENPP6 | |
D88534_s_at | 60.55 | PNLIP | Pancreatic lipase | affy_rg_u34a | ENSRNOG00000017725 | HGNC:9155 | PNLIP | HGNC:9155 | PNLIP | |
rc_AA901342_at | 49.87 | OSP | Claudin 11/OL specific protein | affy_rg_u34b | ENSRNOG00000010263 | HGNC:8514 | CLDN11 | HGNC:8514 | CLDN11 | |
D38380_g_at | 44.63 | Tf | Transferrin | affy_rg_u34a | ENSRNOG00000030625 | HGNC:11740 | TF | HGNC:11740 | TF | |
rc_AI101500_at | 38.59 | ESTs, no homologies found | ||||||||
M22357_g_at | 38.32 | MAG | Myelin-associated glycoprotein | affy_rg_u34a | ENSRNOG00000021023 | HGNC:6783 | MAG | HGNC:6783 | MAG | |
rc_AA893670_at | 36 | TPD52 | Tumor protein D52 | HGNC:12005 | TPD52 | |||||
rc_AI009946_at | 31.34 | CPM | Carboxypeptidase M | affy_rg_u34b | ENSRNOG00000034134 | HGNC:2311 | CPM | HGNC:2311 | CPM | |
rc_AI236200_at | 29.86 | MAN1A1 | Mannosidase 1,α | affy_rg_u34c | ENSRNOG00000000800 | HGNC:6821 | MAN1A1 | HGNC:6821 | MAN1A1 | |
rc_AA800851_s_at | 29.04 | SEPT5 | Septin 5 | affy_rg_u34a | ENSRNOG00000046981 | HGNC:4440 | GP1BB | HGNC:4440 | GP1BB | |
rc_AI228110_s_at | 26.91 | UGT8 | UDP-glucuronosyltransferase 8 | affy_rg_u34a | ENSRNOG00000009345 | HGNC:12555 | UGT8 | HGNC:12555 | UGT8 | |
rc_AI232970_at | 25.81 | GPD1 | Glycerol 3-phosphate dehydrogenase | affy_rg_u34c | ENSRNOG00000019213 | HGNC:4455 | GPD1 | HGNC:4455 | GPD1 | |
rc_AI232373_at | 25.63 | APXL | Thyroid hormone-response protein-1 | affy_rg_u34c | ENSRNOG00000024322 | HGNC:630 | SHROOM2 | HGNC:630 | SHROOM2 | |
S85184_at | 24.93 | CTSL | Cathepsin L | HGNC:2537 | CTSL | |||||
rc_AI144614_at | 23.75 | TMEM10 | Transmembrane protein TMP10 | affy_rg_u34c | ENSRNOG00000022386 | HGNC:20707 | OPALIN | HGNC:20707 | OPALIN | |
rc_AI230247_s_at | 22.32 | SEPP1 | Selenoprotein P | HGNC:10751 | SEPP1 | |||||
rc_AI058796_at | 21.71 | Hypothetical protein DKFZp566N034 | affy_rg_u34b | ENSRNOG00000003769 | HGNC:25380 | TMEM163 | HGNC:25380 | TMEM163 | ||
rc_AI232194_at | 21.41 | CHN2 | Chimerin 2 | affy_rg_u34a | ENSRNOG00000009411 | HGNC:1944 | CHN2 | HGNC:1944 | CHN2 | |
D28560_at | 21.11 | ENPP2 | Ectonuc. pyrophos./phosphodiesterase 2 | affy_rg_u34a | ENSRNOG00000004089 | HGNC:3357 | ENPP2 | HGNC:3357 | ENPP2 | |
rc_AI072835_at | 20.82 | SEMA5A | Semaphorin 5A | affy_rg_u34c | ENSRNOG00000011977 | HGNC:10736 | SEMA5A | HGNC:10736 | SEMA5A | |
rc_AA943765_at | 19.84 | SYTL2 | Synaptotagmin-like 2 | affy_rg_u34b | ENSRNOG00000030776 | HGNC:15585 | SYTL2 | HGNC:15585 | SYTL2 | |
rc_AI072720_at | 19.7 | GALNT5 | N-acetylgalactosaminyltransferase 5 | affy_rg_u34c | ENSRNOG00000021472 | HGNC:29208 | ERMN | HGNC:29208 | ERMN | |
rc_AA925520_at | 19.7 | ADP-ribosylation guan. nuc. factor 6a-like | ||||||||
rc_AI007768_at | 19.56 | PPP1R14A | Protein phosphatase 1, reg. subunit 14a | affy_rg_u34b | ENSRNOG00000020676 | HGNC:14871 | PPP1R14A | HGNC:14871 | PPP1R14A | |
rc_AI234146_at | 19.03 | CSRP1 | Cysteine and glycine-rich protein 1 | affy_rg_u34a | ENSRNOG00000008937 | HGNC:2469 | CSRP1 | HGNC:2469 | CSRP1 | |
rc_AI112149_at | 18.77 | EDG2 | Endothelial diff., LPA G-prot.-coup.-R, 2 | affy_rg_u34c | ENSRNOG00000013656 | HGNC:3166 | LPAR1 | HGNC:3166 | LPAR1 | |
rc_AI229178_at | 18.25 | FGFR2 | Fibroblast growth factor receptor 2 | affy_rg_u34c | ENSRNOG00000016374 | HGNC:3689 | FGFR2 | HGNC:3689 | FGFR2 | |
AF016269_at | 18.13 | KLK6 | Kallikrein 6 | affy_rg_u34a | ENSRNOG00000031927 | HGNC:6367 | KLK6 | HGNC:6367 | KLK6 | |
rc_AI233688_at | 18 | PLS1 | Plastin 1 | HGNC:9090 | PLS1 | |||||
rc_AA963260_at | 17.75 | EPB41L2 | Erythrocyte memb. prot. band 4.1-like 2 | affy_rg_u34b | ENSRNOG00000012346 | HGNC:3379 | EPB41L2 | HGNC:3379 | EPB41L2 | |
rc_AI013705_at | 17.03 | HTRA1 | Protease, serine, 11 (IGF binding) | affy_rg_u34b | ENSRNOG00000020533 | HGNC:9476 | HTRA1 | HGNC:9476 | HTRA1 | |
rc_AI071861_at | 17.03 | BMP4 | Bone morphogenetic protein 4 | affy_rg_u34c | ENSRNOG00000009694 | HGNC:1071 | BMP4 | HGNC:1071 | BMP4 | |
X68101_at | 16.91 | DOCK9 | Dedicator of cytokinesis 9 | affy_rg_u34a | ENSRNOG00000011969 | HGNC:14132 | DOCK9 | HGNC:14132 | DOCK9 | |
rc_AI232059_at | 16.91 | ASPA | Aspartoacylase | affy_rg_u34c | ENSRNOG00000019659 | HGNC:756 | ASPA | HGNC:756 | ASPA | |
rc_AA899764_at | 16.91 | TSPAN2 | Tetraspanin 2 | affy_rg_u34b | ENSRNOG00000023338 | HGNC:20659 | TSPAN2 | HGNC:20659 | TSPAN2 | |
rc_AI013502_at | 16.91 | LHFPL2 | Lipoma HMGIC fusion partner-like 2 | affy_rg_u34b | ENSRNOG00000011032 | HGNC:6588 | LHFPL2 | HGNC:6588 | LHFPL2 | |
rc_AA850738_at | 16.68 | GRAMD3 | HCV NS3-transactivated protein 2 | affy_rg_u34b | ENSRNOG00000015225 | HGNC:24911 | GRAMD3 | HGNC:24911 | GRAMD3 | |
rc_AI029544_at | 16 | SPEER4F | Spermatogenesis assoc. glu-rich prot. 4f | |||||||
rc_AI030921_i_at | 15.78 | CMTM7 | Chemokine-like factor super family 7 | HGNC:19178 | CMTM7 | |||||
rc_AI112086_at | 15.56 | PTPRD | Prot. tyrosine phos'ase, receptor type, D | HGNC:9668 | PTPRD | |||||
AJ131902_g_at | 15.45 | GAS7 | Growth arrest specific 7 | affy_rg_u34a | ENSRNOG00000049361 | HGNC:4169 | GAS7 | HGNC:4169 | GAS7 | |
rc_AI009484_at | 15.45 | GSN | Gelsolin | affy_rg_u34b | ENSRNOG00000018991 | HGNC:4620 | GSN | HGNC:4620 | GSN | |
rc_AA945734_at | 15.35 | Putative phosphatase subunit | ||||||||
U37142_at | 15.14 | BCAN | Brevican | affy_rg_u34a | ENSRNOG00000018798 | HGNC:23059 | BCAN | HGNC:23059 | BCAN | |
M93669_at | -49.52 | SCG2 | Secretogranin II | affy_rg_u34a | ENSRNOG00000015055 | HGNC:10575 | SCG2 | HGNC:10575 | SCG2 | |
J03627_at | -37.01 | S100A10 | S100 calcium binding protein A10 | affy_rg_u34a | ENSRNOG00000023226 | HGNC:10487 | S100A10 | HGNC:10487 | S100A10 | |
rc_AA899590_at | -27.47 | ESTs, no homologies found | affy_rg_u34b | ENSRNOG00000008450 | HGNC:10452 | RRM2 | HGNC:10452 | RRM2 | ||
rc_AA899854_at | -25.81 | TOP2A | Topoisomerase (DNA) 2α | affy_rg_u34a | ENSRNOG00000032404 | HGNC:11989 | TOP2A | HGNC:11989 | TOP2A | |
rc_AA997800_at | -22.01 | Ki-67 | Antigen Ki-67 (predicted) | affy_rg_u34b | ENSRNOG00000028137 | HGNC:7107 | MKI67 | HGNC:7107 | MKI67 | |
rc_AI228113_s_at | -19.03 | NPTXR | Neuronal pentraxin receptor | affy_rg_u34c | ENSRNOG00000016156 | HGNC:7954 | NPTXR | HGNC:7954 | NPTXR | |
rc_AI176963_at | -18.13 | CITED2 | Cbp/p300-interacting transactivator 2 | affy_rg_u34c | ENSRNOG00000012193 | HGNC:1987 | CITED2 | HGNC:1987 | CITED2 | |
J03624_at | -18 | GALN | Galanin | affy_rg_u34a | ENSRNOG00000015156 | HGNC:4114 | GAL | HGNC:4114 | GAL | |
rc_AA963443_at | -18 | CCND2 | Cyclin D2 | HGNC:1583 | CCND2 | |||||
J02585_at | -17.27 | SCD1 | Stearoyl-coenzyme A desaturase 1 | affy_rg_u34a | ENSRNOG00000013552 | HGNC:10571 | SCD | HGNC:10571 | SCD | |
rc_AA956638_at | -16.45 | UHRF1 | Ubiquitin-like, PHD + RING finger domains 1 | HGNC:12556 | UHRF1 | |||||
rc_AA944180_at | -15.89 | CKS2 | CDC28 protein kinase regulatory subunit 2 | affy_rg_u34b | ENSRNOG00000043379 | HGNC:2000 | CKS2 | HGNC:2000 | CKS2 | |
rc_AA818744_at | -15.56 | CD93 | Complement comp. 1, q subcomp., receptor 1 | HGNC:15855 | CD93 | |||||
rc_AI101009_at | -14.22 | ZCCHC12 | Zinc finger, CCHC domain containing 12 | affy_rg_u34c | ENSRNOG00000013162 | HGNC:27273 | ZCCHC12 | HGNC:27273 | ZCCHC12 | |
rc_AI010123_at | -14.12 | TACC2 | Transforming, acidic coiled-coil cont. protein 2 | affy_rg_u34b | ENSRNOG00000020457 | HGNC:11523 | TACC2 | HGNC:11523 | TACC2 | |
X59864mRNA_g_at | -13.83 | H19 | H19 fetal liver mRNA | HGNC:4713 | H19 | |||||
rc_AI231702_at | -13.74 | CEP152 | Centrosomal protein 152 kDa | HGNC:29298 | CEP152 | |||||
rc_AA819103_at | -13.45 | MEST | Mesoderm specific transcript homolog | HGNC:7028 | MEST | |||||
rc_AA997385_at | -13.36 | USP43 | Ubiquitin specific protease 43 | affy_rg_u34b | ENSRNOG00000037718 | HGNC:16053 | WDR16 | HGNC:16053 | WDR16 | |
rc_AI179576_s_at | -13.27 | HBB | Hemoglobin, β | affy_rg_u34a | ENSRNOG00000049424 | HGNC:4827 | HBB | HGNC:4827 | HBB | |
X60767mRNA_s_at | -13.09 | CDC2 | Cell division cycle control protein 2 | affy_rg_u34a | ENSRNOG00000000632 | HGNC:1722 | CDK1 | HGNC:1722 | CDK1 | |
rc_AI071227_at | -13 | RAD51 | DNA repair protein RAD51 homolog 1 | affy_rg_u34c | ENSRNOG00000037302 | HGNC:9817 | RAD51 | HGNC:9817 | RAD51 | |
rc_AI639088_s_at | -12.73 | ESTs, no homologies found | ||||||||
rc_AA859341_at | -12.38 | SH3PXD2A | SH3 and PX domains 2A | HGNC:23664 | SH3PXD2A | |||||
U17565_g_at | -12.04 | MCM6 | Mini chromosome maintenance deficient 6 | affy_rg_u34a | ENSRNOG00000003703 | HGNC:6949 | MCM6 | HGNC:6949 | MCM6 | |
rc_AI058975_at | -11.96 | SOX11 | SRY-box containing gene 11 | HGNC:11191 | SOX11 | |||||
rc_AI146172_at | -11.88 | NSG2 | Neuron specific gene family member 2 | |||||||
rc_AA900746_at | -11.88 | ESTs, no homologies found | ||||||||
M74223_at | -11.79 | VGF | VGF nerve growth factor inducible | affy_rg_u34a | ENSRNOG00000001416 | HGNC:12684 | VGF | HGNC:12684 | VGF | |
rc_AI103150_at | -11.71 | UBE2C | Ubiquitin-conjugating enzyme E2C | affy_rg_u34c | ENSRNOG00000015131 | HGNC:15937 | UBE2C | HGNC:15937 | UBE2C | |
rc_AI010612_at | -11.47 | TNC | Tenascin C | affy_rg_u34b | ENSRNOG00000049585 | HGNC:5318 | TNC | HGNC:5318 | TNC | |
rc_AA956688_at | -11.39 | CDCA3 | Cell division cycle associated 3 | affy_rg_u34b | ENSRNOG00000015529 | HGNC:14624 | CDCA3 | HGNC:14624 | CDCA3 | |
rc_AI231497_at | -11.31 | KPNA2 | Karyopherinα2 | HGNC:6395 | KPNA2 | |||||
rc_AA893717_at | -11.24 | RACGAP1 | Rac GTPase-activating protein 1 | affy_rg_u34a | ENSRNOG00000018187 | HGNC:9804 | RACGAP1 | HGNC:9804 | RACGAP1 | |
rc_AI012221_at | -11.16 | CLIC1 | Chloride intracellular channel 1 | affy_rg_u34b | ENSRNOG00000029682 | HGNC:2062 | CLIC1 | HGNC:2062 | CLIC1 | |
rc_AI169327_g_at | -11.08 | TIMP1 | Tissue inhibitor of metalloproteinase 1 | affy_rg_u34a | ENSRNOG00000010208 | HGNC:11820 | TIMP1 | HGNC:11820 | TIMP1 | |
rc_AI045594_at | -10.93 | SPBC25 | Spindle pole body component 25 | affy_rg_u34b | ENSRNOG00000006731 | HGNC:24031 | SPC25 | HGNC:24031 | SPC25 | |
rc_AI103106_at | -10.78 | LMNB1 | Lamin B1 | HGNC:6637 | LMNB1 | |||||
rc_AI072698_at | -10.7 | TRAF4AF1 | TRAF4 associated factor 1 | affy_rg_u34c | ENSRNOG00000009334 | HGNC:30767 | KNSTRN | HGNC:30767 | KNSTRN | |
rc_AA851392_at | -10.63 | KIF22 | Kinesin family member 22 | affy_rg_u34b | ENSRNOG00000020281 | HGNC:6391 | KIF22 | HGNC:6391 | KIF22 | |
rc_AA818016_at | -10.56 | CDC23 | Cell division cycle 23 | affy_rg_u34c | ENSRNOG00000024428 | HGNC:9787 | KIF20A | HGNC:9787 | KIF20A | |
rc_AI237713_at | -10.56 | ESTs, no homologies found | affy_rg_u34c | ENSRNOG00000016561 | HGNC:28961 | KIAA0101 | HGNC:28961 | KIAA0101 | ||
rc_AI103682_at | -10.56 | POLA | Polymerase (DNA directed),α1 | affy_rg_u34c | ENSRNOG00000013322 | HGNC:9173 | POLA1 | HGNC:9173 | POLA1 | |
rc_AI232326_at | -10.48 | ESTs, no homologies found | ||||||||
rc_AI145123_at | -10.48 | Similar to ataxin 2-binding protein 1 isoform 2 | ||||||||
rc_AA925012_at | -10.48 | GMNN | Geminin | affy_rg_u34b | ENSRNOG00000018782 | HGNC:17493 | GMNN | HGNC:17493 | GMNN | |
rc_AI104821_at | -10.34 | LRRFIP1 | Leucine rich repeat interacting protein 1 | HGNC:6702 | LRRFIP1 | |||||
AF019974_at | -10.27 | CHGB | Chromogranin B | affy_rg_u34a | ENSRNOG00000021269 | HGNC:1930 | CHGB | HGNC:1930 | CHGB | |
rc_AA943886_at | -10.2 | PLK2 | Polo-like kinase 2 | affy_rg_u34b | ENSRNOG00000011951 | HGNC:19699 | PLK2 | HGNC:19699 | PLK2 | |
rc_AI230215_at | -10.06 | CDCA8 | Cell division cycle associated 8 | affy_rg_u34c | ENSRNOG00000031431 | HGNC:14629 | CDCA8 | HGNC:14629 | CDCA8 |
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