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Install Homebrew OS X package manager:
/usr/bin/ruby -e "$(curl -fsSL https://raw.githubusercontent.com/Homebrew/install/master/install)"
Install ffmpeg with x265 support:
brew install ffmpeg --with-fdk-aac --with-sdl2 --with-freetype --with-libass --with-libvorbis --with-libvpx --with-opus --with-x265
Convert video to x265:
ffmpeg -i input -c:v libx265 -preset medium -crf 28 -c:a aac -b:a 128k output.mp4
Uninstall ffmpeg:
brew uninstall ffmpeg
Uninstall homebrew:
/usr/bin/ruby -e "$(curl -fsSL https://raw.githubusercontent.com/Homebrew/install/master/uninstall)"
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