Skim+latexmk+biber+uplatex+dvipdfmx

.latexmkrc

#!/usr/bin/env perl
$latex            = 'uplatex -synctex=1';
$latex_silent     = 'uplatex -synctex=1';
$bibtex           = 'pbibtex';
$biber            = 'biber --bblencoding=utf8 -u -U --output_safechars';
$dvipdf           = 'dvipdfmx %O -o %D %S';
$makeindex        = 'mendex %O -o %D %S';
$max_repeat       = 5;
$pdf_mode	  = 3; # generates pdf via dvipdfmx

# Prevent latexmk from removing PDF after typeset.
# This enables Skim to chase the update in PDF automatically.
$pvc_view_file_via_temporary = 0;

# Use Skim as a previewer
$pdf_previewer    = "open -ga /Applications/Skim.app";