mkuhn

# with the help of decorators, keep track of the functions
# we would like to use for fitting
fit_functions = []

def fit_func(f):
  fit_functions.append(f)
  return f

class C(object):

mkuhn

#!/usr/bin/perl -w

my $columns = 50;
my $gapped = 0;

my $progname = $0;
$progname =~ s/^.*?([^\/]+)$/$1/;

my $usage = "Usage: $progname [<Stockholm file(s)>]\n";
$usage .=   "             [-h] print this help message\n";

mkuhn

#!/usr/bin/env python

import readline
import os
import sys
import re

if len(sys.argv) == 1:
    print >> sys.stderr, "Usage: igrep[.py] file1 [file2 ...]"

mkuhn

javascript:var%20metas=document.getElementsByTagName('meta');var%20a='';for(i=0;i<metas.length;i++){if(metas[i].getAttribute('name')=='citation_doi'){a=metas[i].getAttribute('content')}}if(a){location.href='http://shortdoi.org/'+a}else{a=document.documentElement.innerHTML.match(/doi%20*[:=]%20*10[-/0-9a-z.]\/[-/0-9a-z.]+/mig)||document.documentElement.innerHTML.match(/dx.doi.org\/10[-/0-9a-z.]+/mig);if(a==null){alert('Could%20not%20find%20DOI!')}else{a=a.map(function(x){return%20x.match('10.*')[0]});var%20d=a[0];if(a.length>1){var%20c=new%20Array();for(i%20in%20a){if(c[a[i]]){c[a[i]]++}else{c[a[i]]=1}}var%20m=0;d=null;for(i%20in%20c){if(c[i]>m){m=c[i];d=i}else%20if(c[i]==m){d=null}}}if(d==null){alert('More%20than%20one%20DOI%20found!')}else{location.href='http://shortdoi.org/'+d}}}

mkuhn

p <- ggplot(d,aes(x+0.05,y+0.05))+geom_tile(aes(fill=enrichment)) + scale_fill_gradient(low="white", high="steelblue", limits=c(0,120))
p <- p + xlab("x") + ylab("y")
p <- p + geom_point(aes(x=x+0.05, y=y+0.05, colour=pred),size=20) + scale_colour_gradient(low="white", high="steelblue", limits=c(0,120))
print(p)

mkuhn

pred <- ddply(data.frame(x=c(5:65)*0.01), .(x), function(t) data.frame(x = t$x, y = c(5:85)*0.01) )
pred$enrichment <- predict(sigmoid, pred)

max_pred <- max(pred$enrichment, d$enrichment)

p <- ggplot(pred,aes(x,y))+geom_tile(aes(fill=enrichment))+scale_fill_gradient(low = "white", high = "steelblue",limits=c(0,max_pred))

p <- p + xlab("x") + ylab("y")
p <- p + geom_point(data=d,aes(x=x, y=y, colour=enrichment),size=20) +scale_colour_gradient(low = "white", high = "steelblue",limits=c(0,max_pred))
print(p)

mkuhn

library(ggplot2)

df <- data.frame( n=c("a","a","b","b","c","c"), x = rep(c(1,2), 3), y = rep(c(1), 6), l = as.factor(c(1,1,0,0,0,0)))

# Contents of df:
#   n x y l
# 1 a 1 1 1
# 2 a 2 1 1
# 3 b 1 1 0
# 4 b 2 1 0

mkuhn

library(ggplot2)
library(gridExtra)

mtcars$cyl <- ordered(mtcars$cyl)
p <- ggplot(mtcars, aes(mpg, hp, colour = cyl)) + geom_point()

p1 <- p + theme(legend.position = "none")

p2 <- ggplot(mtcars, aes(x=mpg, group=cyl, colour=cyl))
p2 <- p2 + stat_density(fill = NA, position="dodge")

mkuhn

// International Chemical Identifier Regex, by lo sauer - lsauer.com
// Morphine InchI:
var x="InChI=1S/C17H19NO3/c1-18-7-6-17-10-3-5-13(20)16(17)21-15-12(19)4-2-9(14(15)17)8-11(10)18/h2-5,10-11,13,16,19-20H,6-8H2,1H3/t10-,11+,13-,16-,17-/m0/s1"

// applying an organic character-subset
// we could check for the length property, but in case of 0 matches 'null' is returned -> hence !!.. \ generally equal to Boolean(..) 
!!x.trim().match(/^((InChI=)?[^J][0-9BCOHNSOPrIFla+\-\(\)\\\/,pqbtmsih]{6,})$/ig)
>true
//generic:
x.trim().match(/^((InChI=)?[^J][0-9a-z+\-\(\)\\\/,]+)$/ig)

mkuhn

library(ggplot2)
library(gtable)

# create example data
set.seed(42)
dataset_names <- c("Human", "Mouse", "Fly", "Worm")
datasets <- data.frame(name = factor(dataset_names, levels=dataset_names), parity = factor(c(0, 0, 1, 0)), v50 = runif(4, max=0.5), y=1:4)
data <- data.frame( dataset1 = rep(datasets$name, 4), dataset2 = rep(datasets$name, each = 4), z = runif(16,min = 0, max = 0.5) )

pal <- c("#dddddd", "#aaaaaa")