int_object.py

print(0x10000000000000000 is 0x10000000000000000)
#=> True

import dis
b = dis.Bytecode(lambda: 0x10000000000000000 is 0x10000000000000000)
print(b.dis())
#=>
#  4           0 LOAD_CONST               1 (18446744073709551616)
#              2 LOAD_CONST               1 (18446744073709551616)
#              4 COMPARE_OP               8 (is)
#              6 RETURN_VALUE

print(b.info())
#=>
# Name:              <lambda>
# Filename:          int_object.py
# Argument count:    0
# Kw-only arguments: 0
# Number of locals:  0
# Stack size:        2
# Flags:             OPTIMIZED, NEWLOCALS, NOFREE
# Constants:
#    0: None
#    1: 18446744073709551616

int_object.rb

p(0x10000000000000000.equal? 0x10000000000000000)
# => false

puts RubyVM::InstructionSequence.compile("0x10000000000000000.equal? 0x10000000000000000").disasm
# =>
# == disasm: #<ISeq:<compiled>@<compiled>:1 (1,0)-(1,46)>=================
# 0000 putobject        18446744073709551616                            (   1)[Li]
# 0002 putobject        18446744073709551616
# 0004 opt_send_without_block <callinfo!mid:equal?, argc:1, ARGS_SIMPLE>, <callcache>
# 0007 leave