Summary: use good/established messaging patterns like Enterprise Integration Patterns. Don't make up your own. Don't expose transport implementation details to your application.
As much as possible, I prefer to hide Rabbit's implementation details from my application. In .Net we have a Broker abstraction that can communicate through a lot of different transports (rabbit just happens to be our preferred one). The broker allows us to expose a very simple API which is basically:
- start/stop subscription