StackOverflow question: https://stackoverflow.com/questions/58191627

testpygame.py

import pygame.midi
import time

pygame.midi.init()

#list all midi devices
for x in range( 0, pygame.midi.get_count() ):
    print(x,"=",pygame.midi.get_device_info(x))

player = pygame.midi.Output(2)
player.set_instrument(0)
player.note_on(60, 127)
print("PLAYING")
time.sleep(1)
player.note_off(60, 127)
print("STOPPED")
del player
pygame.midi.quit()

C:\tmp>python3 testpygame.py
pygame 1.9.6
Hello from the pygame community. https://www.pygame.org/contribute.html
0 = (b'MMSystem', b'Microsoft MIDI Mapper', 0, 1, 0)
1 = (b'MMSystem', b'VirtualMIDISynth #1', 0, 1, 0)
2 = (b'MMSystem', b'Microsoft GS Wavetable Synth', 0, 1, 0)
PLAYING
STOPPED

$ python3 testpygame.py
pygame 1.9.6
Hello from the pygame community. https://www.pygame.org/contribute.html
0 = (b'CoreMIDI', b'VMPK Output', 1, 0, 0)
1 = (b'CoreMIDI', b'VMPK Input', 0, 1, 0)
2 = (b'CoreMIDI', b'SimpleSynth virtual input', 0, 1, 0)
PLAYING
STOPPED

Output in Linux:
0 = (b'ALSA', b'Midi Through Port-0', 0, 1, 0)
1 = (b'ALSA', b'Midi Through Port-0', 1, 0, 0)
2 = (b'ALSA', b'UM-2 MIDI 1', 0, 1, 0) <-- here is my synth
3 = (b'ALSA', b'UM-2 MIDI 1', 1, 0, 0)
4 = (b'ALSA', b'UM-2 MIDI 2', 0, 1, 0)
5 = (b'ALSA', b'UM-2 MIDI 2', 1, 0, 0)
PLAYING
STOPPED