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<!DOCTYPE html> |
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<meta charset="utf-8"> |
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<title>A Cates Plot</title> |
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<style> |
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body { |
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font-family: "Helvetica Neue", Helvetica, Arial, sans-serif; |
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position: relative; |
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} |
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g.face { |
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cursor: pointer; |
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} |
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circle.face { |
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stroke: lightgrey; |
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} |
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circle.eye { |
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stroke: #000; |
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stroke-width: 1px; |
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fill: none; |
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} |
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path.mouth { |
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stroke: #000; |
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stroke-width: 1px; |
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fill: none; |
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} |
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text { |
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text-anchor: middle; |
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} |
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text.subtitle { |
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font-size: smaller; |
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fill: lightgrey; |
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} |
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div#legend { |
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position: absolute; |
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left: 480px; |
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top: 25px; |
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width: 200px; |
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height: 400px; |
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font-size: smaller; |
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} |
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p.reference { |
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font-size:smaller; |
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width: 450px; |
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padding-left: 15px; |
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} |
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</style> |
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<script src="http://d3js.org/d3.v3.min.js"></script> |
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<body> |
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<div id='legend'> |
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<p id='frequency'></p> |
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</div> |
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<script> |
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var width = 500, |
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height = 500, |
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duration = 3000, |
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change_interval = 5000, |
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margin = { left: 20, right: 20, top: 40, bottom: 20 }, |
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total, |
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control_data, |
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intervention_data |
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data; |
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var control_frequencies = [ |
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{ |
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name: "would have died of a heart attack", |
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colour: "white", |
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smile: -1, |
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count: 20 |
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}, |
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{ |
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name: "would have been healthy", |
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colour: "chartreuse", |
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smile: 1, |
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count: 180 |
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} |
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]; |
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var intervention_frequencies = [ |
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{ |
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name: "may still die of a heart attack", |
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colour: "white", |
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smile: -1, |
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count: 16 |
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}, |
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{ |
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name: "might have died of a heart attack but didn't", |
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colour: "yellow", |
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smile: 1, |
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count: 4 |
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}, |
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{ |
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name: "would have been healthy, but are now a bit unhappy about taking drugs every day", |
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colour: "lightgreen", |
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smile: 0, |
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count: 174 |
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}, |
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{ |
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name: "would have been healthy, but now have aches and pains ", |
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colour: "lightskyblue", |
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smile: -0.5, |
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count: 5 |
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}, |
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{ |
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name: "would have been healthy, but now have diabetes – maybe earlier than otherwise", |
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colour: "royalblue", |
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smile: -0.5, |
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count: 1 |
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} |
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]; |
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var data_from_frequencies = function(frequencies) { |
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d = []; |
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frequencies.forEach(function(outcome) { |
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for(i=0; i < outcome.count; i++) { |
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d.push(outcome); |
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} |
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}); |
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return d; |
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}; |
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control_data = data_from_frequencies(control_frequencies); |
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intervention_data = data_from_frequencies(intervention_frequencies); |
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total = control_frequencies.reduce(function(count, outcome) { return count + outcome.count; }, 0); |
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var side = Math.ceil(Math.sqrt(total)); |
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var x = d3.scale.ordinal().domain(d3.range(side)).rangeRoundBands([margin.left, width - margin.right], 0.2); |
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var y = d3.scale.ordinal().domain(d3.range(side)).rangeRoundBands([margin.top, height - margin.top], 0.2); |
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var size = x.rangeBand()/2; |
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var smile_size = d3.scale.linear().domain([-1,1]).range([-size/2,+size/2]); |
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var svg = d3.select("body").append("svg") |
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.attr("width", width) |
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.attr("height", height) |
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var title = svg.append("text") |
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.attr("class", "title") |
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.attr("x", width/2) |
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.attr("y", margin.top/3); |
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var subtitle = svg.append("text") |
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.attr("class", "subtitle") |
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.attr("x", width/2) |
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.attr("y", (4*(margin.top/5))) |
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.text("Move your mouse over each face to find out what happens to it"); |
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var mouth_path = function(d,i) { |
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dx = size/2; |
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s = smile_size(d.smile); |
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dyt = (size/3)-(s/3); |
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dyb = (size/3)+(2*s/3); |
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return "M"+(-dx)+","+dyt+" Q0,"+dyb+" "+dx+","+dyt; |
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}; |
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var face_position = function(d,i) { return "translate("+x(i % side)+","+y(Math.floor(i/side))+")"; }; |
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var group = undefined; |
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var selected = undefined; |
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var data = undefined; |
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var updateLegend = function() { |
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if(selected == undefined) { |
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d3.select("#frequency").transition().style("opacity", 0); |
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} else { |
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d = data[selected]; |
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d3.select("#frequency").text("Out of "+group+", "+d.count+" "+d.name+".").transition().style("opacity", 1); |
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} |
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} |
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var draw = function(new_data) { |
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title.text(group); |
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data = new_data; |
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updateLegend(); |
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faces = svg.selectAll("g.face") |
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.data(data); |
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newfaces = faces.enter().append("g") |
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.classed("face",true) |
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.attr("transform", face_position ) |
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.on("mouseenter", function(d,i) { |
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selected = i; |
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updateLegend(); |
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}) |
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.on("mouseleave", function(d,i) { |
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selected = undefined; |
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updateLegend(); |
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}); |
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newfaces.append("circle") |
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.classed("face", true) |
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.attr("r", size) |
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.attr("fill", function(d,i) { return d.colour; }) |
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.attr("cx", 0) |
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.attr("cy", 0); |
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newfaces.append("circle") |
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.classed("eye",true) |
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.attr("r", size/8) |
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.attr("cx", -size/3) |
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.attr("cy", -size/4); |
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newfaces.append("circle") |
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.classed("eye",true) |
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.attr("r", size/8) |
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.attr("cx", +size/3) |
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.attr("cy", -size/4); |
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newfaces.append("path") |
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.classed("mouth", true) |
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.attr("d", mouth_path); |
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faces.transition() |
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.duration(duration) |
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.attr("transform", face_position); |
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faces.select("circle.face") |
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.attr("class", function(d,i) { return "face "+d.colour+" "+((selected != undefined && data[selected].colour == d.colour) ? "hover" : ""); }) |
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.transition() |
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.duration(duration) |
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.attr("fill", function(d,i) { return d.colour; }); |
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faces.select("path.mouth").transition() |
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.duration(duration) |
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.attr("d", mouth_path); |
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}; |
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var control_displayed = true; |
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group = ""+total+" people not taking statins"; |
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draw(control_data); |
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setInterval(function() { |
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if(control_displayed) { |
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control_displayed = false; |
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group = ""+total+" people taking statins"; |
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draw(intervention_data); |
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} else { |
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control_displayed = true; |
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group = ""+total+" people not taking statins"; |
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draw(control_data); |
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} |
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}, change_interval); |
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</script> |
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<p class='reference'>There are no agreed rates even for accepted side effects of statins. In the diagram for those taking statins the risk of diabetes was estimated from an RCT, Ridker PM, Danielson E, Fonseca FA, Genest J, Gotto AM, Kastelein JJ et al (2008) Rosuvastatin to prevent vascular events in men and women with elevated C-reactive protein. New England Journal of Medicine 359:2195-207. Muscle problems are an accepted risk, occur in less than 1 in 200 people according to trials. However they are linked to drug interactions, which one would expect to be minimal within a trial, and have therefore been estimated here from an observational study, Buettner C, Davis RB, Leveille SG, Mittlean MA, Mukamal KJ. (2008) Prevalence of musculoskeletal pain and statin use. Journal of General Internal Medicine 23:1182-6. </p> |
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<p class='reference'>Source code for this page available under an open source licence from <a href='https://gist.github.com/tamc/024168df8660eeca26aa'>https://gist.github.com/tamc/024168df8660eeca26aa</a>.</p> |
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</body> |
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