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Despite their widespread application, the mechanism of liposome formation is not . Examples are doxorubicin, cytosine arabinose, cortisones, biological Key words: Liposome; Cancer; Doxorubicin ; Extrusion; Freeze-thawed . excellent examples of the therapeutic benefits of liposomal drug delivery and the 2 Nov 2015 Liposomes have useful properties that promote them for the use as a drug For example, anthracyclines help to stop the growth of rapidly Structure of a liposome formed by a phospholipid bilayer. . An example of this is the pH-triggered permeability change of a heterogeneous liposome. 29 Oct 2010 Liposomes are often used to deliver a molecular cargo such as DNA for .. For example, in liposomes lacking cholesterol, high density A liposome is a spherical vesicle having at least one lipid bilayer. Liposomes are most often composed of phospholipids, especially phosphatidylcholine, but may also include other lipids, such as egg phosphatidylethanolamine, so long as they are compatible with lipid bilayer structure. Liposomal formulations: examples. Drugs with severe harmful toxic effects p p. Drugs with severe, harmful toxic effects. ? Doxorubicin (DOXIL®/ Caelyx®). 22 Feb 2013 On the basis of their size and number of bilayers, liposomes can also be classified into one of two categories: (1) multilamellar vesicles (MLV) and (2) unilamellar vesicles. In unilamellar liposomes, the vesicle has a single phospholipid bilayer sphere enclosing the aqueous solution. Figure 1. Structural and design considerations for liposomal drug delivery. Liposomes can be surface functionalized to endow stealth through PEGylation and to
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