The phmm folder implements a pairwise-HMM sequence aligner: given two sequences,
it produces either posterior base-alignment probabilities, a maximum-likelihood (ML)
alignment, or a "alignment envelope" that constrains downstream folding.
Discover gists
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| <?xml version="1.0" encoding="utf-8"?> | |
| <fileSnapshot xmlns:xsd="http://www.w3.org/2001/XMLSchema" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance"> | |
| <files> | |
| <file path="C:\ProgramData\chocolatey\lib\gfs\gfs-windows-x86_64.tar.gz.txt" checksum="E67E7AEA83775D73BB41D2D2CDD9FC2B" /> | |
| <file path="C:\ProgramData\chocolatey\lib\gfs\gfs.nupkg" checksum="25F867ED9DEE254C5160CFC8FBD370CF" /> | |
| <file path="C:\ProgramData\chocolatey\lib\gfs\gfs.nuspec" checksum="7F034F0427F20D7D1CC150851717F51E" /> | |
| <file path="C:\ProgramData\chocolatey\lib\gfs\tools\chocolateyInstall.ps1" checksum="B031BF097D626CB1219B3D5876157793" /> | |
| <file path="C:\ProgramData\chocolatey\lib\gfs\tools\gfs.exe" checksum="7D885447FCEB796A94B7F6980CE30E11" /> | |
| </files> | |
| </fileSnapshot> |
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| <?xml version="1.0" encoding="utf-8"?> | |
| <fileSnapshot xmlns:xsd="http://www.w3.org/2001/XMLSchema" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance"> | |
| <files> | |
| <file path="C:\ProgramData\chocolatey\lib\filebrowser\filebrowser.nupkg" checksum="9C57C0C7AA2A6D4BC75F21C5BCA1AB61" /> | |
| <file path="C:\ProgramData\chocolatey\lib\filebrowser\filebrowser.nuspec" checksum="C32B45B0AC10A42F394306C9CF23D6B8" /> | |
| <file path="C:\ProgramData\chocolatey\lib\filebrowser\windows-amd64-filebrowser.zip.txt" checksum="3A4DAADCA3D36AFC3FA1547B72E4AFA4" /> | |
| <file path="C:\ProgramData\chocolatey\lib\filebrowser\tools\CHANGELOG.md" checksum="0C82219C27735699FD81E9CE22E02A0C" /> | |
| <file path="C:\ProgramData\chocolatey\lib\filebrowser\tools\chocolateyInstall.ps1" checksum="1C7EBC34D90AFE8E5DE32C12F90291CB" /> | |
| <file path="C:\ProgramData\chocolatey\lib\filebrowser\tools\filebrowser.exe" checksum="1FA715B59B5E09C648C888FF1EB26F61" /> | |
| <file path="C:\ProgramData\chocolatey\lib\filebrowser\tools\LICENSE" che |
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| // Chapter 22, snippet 22-01 (Dart): the loyalty discount added to the | |
| // tab split, extracted from Rosie's Coffee Shop's app. No database, | |
| // no view, and no framework: just the two rules every port has to | |
| // reproduce, and the cases that separate integer from floating | |
| // point. | |
| // | |
| // GENERATED by scripts/gerar-22-01-dart-en.sh from the companion | |
| // repository. Don't edit by hand: edit the companion and generate | |
| // again. |
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| // Capítulo 22, snippet 22-01 (Dart): o desconto de fidelidade somado à | |
| // divisão de comanda, extraídos do app da cafeteria da Dona Célia. Sem | |
| // banco, sem view e sem framework: só as duas regras que todo porte | |
| // precisa reproduzir, e os casos que separam inteiro de ponto | |
| // flutuante. | |
| // | |
| // GERADO por scripts/gerar-22-01-dart.sh a partir do repositório | |
| // companion. Não edite à mão: edite o companion e gere de novo. | |
| // ---- o ciclo de vida da comanda ---- |
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| Humanin is a small mitochondrial-derived peptide (MDP) — one of a handful of short bioactive peptides that are encoded not in the nuclear genome but within the mitochondrial genome, specifically in a region of the 16S ribosomal RNA gene (MT-RNR2). It's typically 21–24 amino acids long, and its discovery in the early 2000s was notable because it revealed that mitochondrial DNA, long thought to encode only proteins involved in oxidative phosphorylation, could also produce signaling peptides with effects far beyond the mitochondrion itself. | |
| How it was discovered | |
| Humanin was first identified in a screen for genes that could protect neurons from the toxic effects associated with Alzheimer's disease-related amyloid-beta protein. Researchers found that a short peptide could suppress neuronal cell death triggered by mutant genes linked to familial Alzheimer's, and traced its origin back to mitochondrial DNA rather than the nucleus — a surprising find at the time. | |
| Proposed mechanisms and biological roles | |
| Research on |
Condensed Threat & Vulnerability Brief – 30 Jul 2026
| Area | Key Points | Mitigation |
|---|---|---|
| Mac‑OS Ad‑Traffic (North Korea) | • Legitimate ad traffic hijacked to show realistic, full‑screen fake update screens. • Triggers crypto‑stealing malware upon user install. • Part of “Contagious Interview” – relies on convincing UI to boost compliance. |
• Avoid installing from unknown or ad‑loaded apps. • Keep macOS & security tools up‑to‑date. |
| CVE‑2026‑18245 – AWS Amplify UI React | • Authenticated users can inject arbitrary JS via malformed Studio component/theme schema. • Runs in browsers, CI/CD, SSR – full code execution. • Regression of CVE‑2025‑4318. |
Upgrade to @aws‑amplify/codegen‑ui‑react v2.20.6+. |
| CVE‑2026‑12943 – IBM HMC Firmware | • CVSS 9.8 – unauthenticated command execution with full HMC/Novalink privileges.• Affects HMC firmware 10.3‑11.1 (Novalink). | Patch applied 30 Jul 2026 5:57 pm – apply IBM update immediately. |
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| <?xml version="1.0" encoding="utf-8"?> | |
| <fileSnapshot xmlns:xsd="http://www.w3.org/2001/XMLSchema" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance"> | |
| <files> | |
| <file path="C:\ProgramData\chocolatey\lib\alertmanager\alertmanager-0.33.1.windows-amd64.zip.txt" checksum="D70BBD2532B1D8EB8F671E4EBBACE478" /> | |
| <file path="C:\ProgramData\chocolatey\lib\alertmanager\alertmanager.nupkg" checksum="93B4A3631100598B23A7DFC82C551352" /> | |
| <file path="C:\ProgramData\chocolatey\lib\alertmanager\alertmanager.nuspec" checksum="A17BF8DE583AA6D21CC3E1960A7DD72C" /> | |
| <file path="C:\ProgramData\chocolatey\lib\alertmanager\tools\chocolateyInstall.ps1" checksum="78AF4107B2D45A966B6B1BD6DF582EE0" /> | |
| <file path="C:\ProgramData\chocolatey\lib\alertmanager\tools\alertmanager-0.33.1.windows-amd64\alertmanager.exe" checksum="1A2E9B0C0F0A69889F0B6DE562368C31" /> | |
| <file path="C:\ProgramData\chocolatey\lib\alertmanager\tools\alertmanager-0.33.1.windows-amd64\alertmanager.yml" checksum="BC41566CFB99A213B90D4B0F0 |
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| id | station | stationid | value | unit | obstime | date | |
|---|---|---|---|---|---|---|---|
| 0 | 流浮山 | RF001 | 0 | mm | 2026-07-31T03:45:00+08:00 | 2026-07-31 | |
| 1 | 湿地公园 | RF002 | 0 | mm | 2026-07-31T03:45:00+08:00 | 2026-07-31 | |
| 2 | 水边围 | N12 | 0 | mm | 2026-07-31T03:45:00+08:00 | 2026-07-31 | |
| 3 | 石岗 | RF003 | M | mm | 2026-07-31T03:45:00+08:00 | 2026-07-31 | |
| 4 | 大美督 | RF004 | 0 | mm | 2026-07-31T03:45:00+08:00 | 2026-07-31 | |
| 5 | 大埔墟 | RF005 | 0 | mm | 2026-07-31T03:45:00+08:00 | 2026-07-31 | |
| 6 | 北潭涌 | RF006 | 0 | mm | 2026-07-31T03:45:00+08:00 | 2026-07-31 | |
| 7 | 滘西洲 | RF007 | 0 | mm | 2026-07-31T03:45:00+08:00 | 2026-07-31 | |
| 8 | 西贡 | N15 | 0 | mm | 2026-07-31T03:45:00+08:00 | 2026-07-31 |
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