TPA ADMINISTRATION Ensure tPA orders are calculated appropriately based on patient's weight; verify with 2nd RN or physician Perform hand hygiene In-Hospital Stroke Alert Protocol: Pocket Card for Stroke Response Team Members Once IV tPA is started, monitor vitals and neurological assessment every 15 Learn more about Activase® (Alteplase) for Acute Ischemic Stroke Treatment. Indications Activase (alteplase) is indicated for the treatment of acute ischemic stroke. TPA Contraindications for Stroke (2013) (1995). Tissue plasminogen activator for acute ischemic Guidelines for the early management of patients with acute DATE TIME ORDERS: Stroke Inclusion/Exclusion Criteria for tPA Allergies: Patient ELIGIBLE for tPA (NO exclusion criteria checked/ALL inclusion criteria met) Clinical Practice Guidelines American Stroke Association . Guidelines are comprehensive statements that provide the highest level of scientific evidence for clinical Analyze: Process and Outcomes Jauch EC, Saver JL, Adams HP Jr, et al. Guidelines for the early management of patients with acute ischemic stroke: Acute Stroke Protocol Purpose: Brouns R. Intravenous thrombolysis with recombinant tissue plasminogen activator in a stroke patient treated with dabigatran. tPA PROTOCOL CHECKLIST Stroke Program Inclusion crtiteria 1. Patient consents to use of tPA Exclusion crtiteria 1. Hemorrhage on CT 2. Prior stroke within 90 days 3. tPA Contraindications provide inclusion/exclusion criteria when deciding to use tPA on a patient with acute ischemic stroke. Thrombolytic therapy is the use of drugs to break up or dissolve blood clots, which are the main cause of both heart attacks and stroke. Thrombolytic therapy is the use of drugs to break up or dissolve blood clots, which are the main cause of both heart attacks and stroke. Activase is a tissue plasminogen activator produced by recombinant DNA technology. It is a sterile, purified glycoprotein of 527 amino acids. 2015 American Heart Association/American Stroke Association Focused Update of the 2013 Guidelines for the Early Management of Patients With Acute Ischemic Stroke Protocol for use of IV tPA in the 3-4.5 hour window Exclusion criteria additional to the current guidelines for IV Intravenous Tissue Plasminogen Activator.
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