chackley

## Vaccine-Autism Evidence
Lancet. 2004 Sep 11-17;364(9438):963-9. MMR vaccination and pervasive developmental disorders: a case-control study. PMID 15364187
294 cases and 4469 controls were included. 1010 cases (78.1%) had MMR vaccination recorded before diagnosis, compared with 3671 controls (82.1%) before the age at which their matched case was diagnosed. After adjustment for age at joining the database, the odds ratio for association between MMR and pervasive developmental disorder was 0.86 (95% CI 0.68-1.09). Our findings suggest that MMR vaccination is not associated with an increased risk of pervasive developmental disorders.
Odds ratio below 1 suggests decreased, not increased, risk of autism with vaccine. CI crosses 1 so the effect of vaccine preventing autism is non-significant.

N Engl J Med. 2002 Nov 7;347(19):1477-82. A population-based study of measles, mumps, and rubella vaccination and autism. PMID 12421889
Of the 537,303 children in the cohort (representing 2,129,864 person-years), 440,655 (82.0 percent) had received t
	Lancet. 2004 Sep 11-17;364(9438):963-9. MMR vaccination and pervasive developmental disorders: a case-control study. PMID 15364187
	294 cases and 4469 controls were included. 1010 cases (78.1%) had MMR vaccination recorded before diagnosis, compared with 3671 controls (82.1%) before the age at which their matched case was diagnosed. After adjustment for age at joining the database, the odds ratio for association between MMR and pervasive developmental disorder was 0.86 (95% CI 0.68-1.09). Our findings suggest that MMR vaccination is not associated with an increased risk of pervasive developmental disorders.
	Odds ratio below 1 suggests decreased, not increased, risk of autism with vaccine. CI crosses 1 so the effect of vaccine preventing autism is non-significant.

	N Engl J Med. 2002 Nov 7;347(19):1477-82. A population-based study of measles, mumps, and rubella vaccination and autism. PMID 12421889
	Of the 537,303 children in the cohort (representing 2,129,864 person-years), 440,655 (82.0 percent) had received t