dominiquesydow/KinFragLib_demo.ipynb

## README.md

      
    Raw
  

              README.md
            
          
    Getting started


Download repository and install conda environment (instructions)
Download this notebook and save to KinFragLib/notebooks folder
If you are interested in using the notebook in presentation mode, install RISE (more information here): pip install RISE


## KinFragLib_demo.ipynb
{
 "cells": [
  {
   "cell_type": "markdown",
   "metadata": {
    "slideshow": {
     "slide_type": "slide"
    }
   },
   "source": [
    "# Quick start to KinFragLib\n",
    "\n",
    "How to load and use the KinFragLib fragment library?"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {
    "slideshow": {
     "slide_type": "fragment"
    }
   },
   "source": [
    "## Table of contents\n",
    "\n",
    "1. Access fragment library\n",
    "2. View all fragments for Gefitinib\n",
    "3. Identify most common fragments in the AP subpocket"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {
    "slideshow": {
     "slide_type": "slide"
    }
   },
   "source": [
    "## Installation\n",
    "\n",
    "- Download repository and install conda environment ([instructions](https://github.com/volkamerlab/kinfraglib#quick-start))\n",
    "- To use this notebook: [Download notebook](https://gist.github.com/dominiquesydow/48b6a850d935ccf4d15906b79a4b1817) and save to `KinFragLib/notebooks` folder"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {
    "slideshow": {
     "slide_type": "slide"
    }
   },
   "source": [
    "## Imports"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 1,
   "metadata": {
    "slideshow": {
     "slide_type": "-"
    }
   },
   "outputs": [],
   "source": [
    "from pathlib import Path\n",
    "\n",
    "from rdkit import Chem\n",
    "from rdkit.Chem import Draw, PandasTools\n",
    "\n",
    "from utils import (\n",
    "    read_fragment_library, \n",
    "    get_fragments_by_ligand, \n",
    "    get_most_common_fragments, \n",
    "    draw_fragmented_ligand, \n",
    "    draw_ligands_from_pdb_ids\n",
    ")\n",
    "\n",
    "# Needed to display ROMol images in DataFrames\n",
    "PandasTools.RenderImagesInAllDataFrames(images=True)"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {
    "slideshow": {
     "slide_type": "slide"
    }
   },
   "source": [
    "## 1. Access fragment library\n",
    "\n",
    "Load the fragment library and access the subpocket fragment pools.\n",
    "\n",
    "Example: AP subpocket"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {
    "slideshow": {
     "slide_type": "subslide"
    }
   },
   "source": [
    "### Load the fragment library"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 2,
   "metadata": {
    "slideshow": {
     "slide_type": "-"
    }
   },
   "outputs": [],
   "source": [
    "PATH_TO_LIB = Path(\"./../data/fragment_library\")"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 3,
   "metadata": {
    "slideshow": {
     "slide_type": "-"
    }
   },
   "outputs": [
    {
     "data": {
      "text/plain": [
       "dict_keys(['AP', 'FP', 'SE', 'GA', 'B1', 'B2', 'X'])"
      ]
     },
     "execution_count": 3,
     "metadata": {},
     "output_type": "execute_result"
    }
   ],
   "source": [
    "fragment_library = read_fragment_library(PATH_TO_LIB)\n",
    "fragment_library.keys()"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {},
   "source": [
    "`fragment_library` is a dictionary containing a `pandas` DataFrame for each of the six subpockets (AP, FP, SE, GA, B1, B2) and the pool X."
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {
    "slideshow": {
     "slide_type": "subslide"
    }
   },
   "source": [
    "### Access fragments in AP subpocket"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 4,
   "metadata": {
    "scrolled": true,
    "slideshow": {
     "slide_type": "-"
    }
   },
   "outputs": [
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      "Number of fragments in AP: 2561\n"
     ]
    }
   ],
   "source": [
    "ap_fragments = fragment_library[\"AP\"]\n",
    "print(f\"Number of fragments in AP: {ap_fragments.shape[0]}\")"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 5,
   "metadata": {
    "slideshow": {
     "slide_type": "-"
    }
   },
   "outputs": [
    {
     "data": {
      "text/html": [
       "<div>\n",
       "<style scoped>\n",
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       "        vertical-align: middle;\n",
       "    }\n",
       "\n",
       "    .dataframe tbody tr th {\n",
       "        vertical-align: top;\n",
       "    }\n",
       "\n",
       "    .dataframe thead th {\n",
       "        text-align: right;\n",
       "    }\n",
       "</style>\n",
       "<table border=\"1\" class=\"dataframe\">\n",
       "  <thead>\n",
       "    <tr style=\"text-align: right;\">\n",
       "      <th></th>\n",
       "      <th>ROMol</th>\n",
       "      <th>ROMol_dummy</th>\n",
       "      <th>ROMol_original</th>\n",
       "      <th>kinase</th>\n",
       "      <th>family</th>\n",
       "      <th>group</th>\n",
       "      <th>complex_pdb</th>\n",
       "      <th>ligand_pdb</th>\n",
       "      <th>alt</th>\n",
       "      <th>chain</th>\n",
       "      <th>atom_subpockets</th>\n",
       "      <th>atom_environments</th>\n",
       "      <th>smiles</th>\n",
       "      <th>smiles_dummy</th>\n",
       "      <th>subpocket</th>\n",
       "    </tr>\n",
       "  </thead>\n",
       "  <tbody>\n",
       "    <tr>\n",
       "      <th>0</th>\n",
       "      <td><img data-content=\"rdkit/molecule\" src=\"data:image/png;base64,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\" alt=\"Mol\"/></td>\n",
       "      <td><img data-content=\"rdkit/molecule\" src=\"data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAMgAAADICAIAAAAiOjnJAAAABmJLR0QA/wD/AP+gvaeTAAAXK0lEQVR4nO2da1RU19mA34EBZhxuylUBTQDTACoIRCLReEMUFRSFIET0QyOptZJkxRaT1NWVxqasNE2VtknIWk1ALnFBiILEcFGIYmkV0JiKiFVRgTDIXQZmBmZmfz82GSZgEIbZ54B5n+WPM3vmnP0O87jPOe/eZ28BIQQQxNAY8R0A8niCYiFMQLEQJqBYCBNQLIQJKBbCBBQLYQKKhTABxUKYgGIhTECxECagWAgTUCyECSgWwgQUC2ECioUwAcVCmIBiIUxAsRAmoFgIE1AshAkoFsIEFAthAoqFMAHFQpiAYiFMQLEQJqBYCBNQLIQJKBbCBBQLYQKKhTABxUKYgGIhTECxECagWAgTUCyECSgWwgQUC2ECioUwAcVCmIBiIUxAsRAmoFgIE1AshAkoluFxdISqqqGX/v5QUMBfNDyBYiFMQLEQJgj5DuDxJCwMTE0Ht5ubeQ2FJ1AsJuTng7//4LZ242cFngoRJqBYCBNQLIQJAlzFHmEBtlgIE1Asw+PoCF5eoFYPvvTxgdOneQ2ID1AsJvT1QWoq30HwCorFhLffhrffBrmc7zj4A8Vigq8vLFkCycl8x8EfKBYrDh2CDz6Azk6+4+AJFMtg5OXBli2g0Qy+dHWFqCh4993Bl/X18LNK7GBfoQFob4eEBMjKAgA4dmyo/OBB8PICY2NobYWYGAgIgIwMsLLiK0xOwRZrohQUwIIFkJUFYjEkJUFU1NBbdnawbx9IpSCVgloNBQWweDHU1fEXK5cQRF9aWkhsLAEgAGTJElJXN9qH794lfn4EgFhYkNxcrkLkDxRLT7KziZ0dASDTppGkJKJWP3oXuZzs2EEAiEBAEhPHtMvUZbKL5eBAPD2JSjX40tublJTwGhAhUinZsmWwoVq6lPzvf+PbPSWFmJgQALJuHenoYBPiJGAKXGNNqix2Tg7Mmwe5uWBpCSkpcPYsuLuP7wjx8XD6NDg4wKlTsGgRXL3KJlDe4dvsR+DgQNLSiIsL6esjhNcWq6mJhIYONlRr15J79yZ0tIYG8swzBICYm5OcHAOFOJmYAi3WsCy2VAp/+QtcvjyUMeKAnJyc0NBtJSVgZQUpKXDqFLi4TOiAzs5w7hzExYFMBi+8AAcODHVaPybwbfYjcHAg//0vuXWL2NuTjg7i7U327h1sNiwsSFAQSUoiVVVEo2EVQENDQ0hICP1b7d37TWOjgY9/+DARCgkA2bWrsuMxuuaaGmIRQvbtI/v3E29v8sEHZOdO8sQTg3rRf7NmkdhY8tln5O5dQ9aenZ09Y8YMALC2tk5JSTHkoXU4d474+Ny1sbGbPXt2VVUVo1o4ZpKK1dpKlEpCdMS6f5/Y2RFHx6FrrKYmkp1N4uOJi8uPJHN1JbGxJCWFNDToH8CdO3dWr15NG6r169c3Gryl+jENDQ3PPPMMAEgkkmPHjjGtixsmo1itrWT+fLJ2LZHLh8QihPzhDwTg4RfvV6+SI0fIxo3E2nrIMIlE5uOz8JVXXsnLy+vq6hpj7RqNJiUlxcLCAgCmT5/OrqEahkKheOmll6jK8fHx/f393NTLiEknVlsb8fYmAMTLi7S2jnt3lYpcvEiSkkhwMAkM/Fp7KWlsbOzn55eYmJifn9/d3f1Tu9fX169atYrusmHDhqampgl9mfGTkpJiamoKAMuWLWtpaeG4dgMyucTq7CT+/gSAPPUU+f77iR5tYGCgqqoqKSkpKCjIzMxMK5lQKKSSlZSUKBQK+mHaUJmbmwOAvb19dnb2RKvXl/Pnz8+cORMAXFxcLl68yFcYE2QSidXVRRYtIgBk7lxi8JZCJpMVFhb+9re/9ff3NzY21komkUhCQkIOHDiwePFiWhIdHd2qR1NpUJqammg8IpHo008/5TcY/ZgsYnV3k4AAAkDc3ckYL5QjIoifH0lMJCUl5Id2Z0z09PSUlJQkJib6+fkJBALqk5mZmb29/RdffKFf/AZHqVQmJCRM3UuuSSGWTEaef54AkNmzSX39mHbRaIiNzdB1urk5WbeO/PnPpLp6fJ27zc3NmZmZzs7OAHD06FG9wmdIWlqaWCwGgKVLlzY3N/MdzjjgX6zeXrJ8+aBVt2+PY8f2dvLll+TXvyaenj9KN9jYkM2bSWrquWvXro3xUIcOHQKAl19+WZ8vwJh///vfTk5OALB9+3a+YxkHPIvV20tWrCAAxMWF3Lql/3FaWgZzWq6ug3q5uXkCgIODQ2RkZEpKyu1Rna2srASAJ554Qv8IWHL37l1TU1MfH5+xJ014h0+x+vrIqlUEgDg7k5s3DXbY27fJP//ZHxMT4+joqNt55ebmtnv37s8//3zkbbxarba3tweAutFH6/FEdnY2APj6+vIdyDjgTSy5XB4d3U17Y9j9mlevXk1OTt60adP06dO1hgkEgvLy8mGfjI6OBoDk5GRWoYwBjUazefPmv/3tb0ra7fAD69evB4AjR47wFZge8COWUqncsGGDnd38RYtktbVc1KhWq6uqqg4fPhwZGWlrayuTyYZ9IDU1lSZFuYjmJzh79iwAODk5qbQjGwmRSqVCodDExOT+/fs8xjZeeBBLqVSGhoYCgJ2d3X+1/TUcovuzaWlubhYIBBKJRDGu1IVB2blzJwC8+eabuoXvvfceAISHh/MVlX5wLVZ/f//GjRtpN1x1dTXHtY/O/PnzAaC0tJSX2vv6+qysrACg9sdtOI3qxIkTvESlN5yKpVKptm7dSkehTMLxIfv37weAxMREXmo/evQoAAQGBuoW0ttVe3v7KZcg5W4EqVqtjo2NPXbsmJWVVXFxsZ+fH2dVj5E1a9YAQFFRES+1p6WlAcCOHTtGFr744osmJia8RKU/3PirUqlefPFFALCysrpw4QI3lY4XhUIhkUgEAsH3E+8AHycNDQ3GxsYikaizs1NbqFQqbW1tAeDbb7/lOJ6Jw0WLpdFo4uLiMjMzJRLJyZMnFy1axEGlemBmZvb8888TQk5zPlHaZ599plarw8PDra2ttYX5+fltbW0+Pj7e3t4cxzNxmItFCNmzZ096erpEIvnqq6+WLl3KusaJQM+GxcXFHNebmZkJP3EeHFY4ZWDaHmo0ml/+8pcAMG3atLKyMqZ1GYTa2loAsLOzU3P4nHJ5eTmMSF+1tLSYmJgIhUKpVMpZJAaErVjp6enUKr7u4fVgzpw5AHDp0iXOaqQjkt944w3dwvfffx8ANm3axFkYhoXtqbCurs7c3PxPf/rTihUrmFZkQIKDg4HDe0O5XP7FF18AwPbt23XLafZhqp4HWV9jdXZ2ymSyzik1rR3HYuXm5nZ1dT377LNPP/20trC6uvq7776zsbFZt24dN2EYHLZi8ZsZ0o+goCChUFhRUdHT08NBdaOkr7Zt22aqXUNsysH0RCuTyczMzIyNjdvb27WFGo1m9+7d7u7uvb29TGvXGzrePD8/n3VFjY2NNH2l+wy0Nn3F5XWewWHbYkkkksWLF6vV6tLSUm2hQCD49ttvb968STvzJyGcNbSpqalqtXrYqJ6TJ0+2tbXNmzdv4cKFrANgB/M81kMzQ5P8FMlZNisjIwN+4jxIRzpMYVg3iZcuXQIAZ2dn3UKaufHw8GBdu36oVCo6ZcOtiQyXfhTnz58HgFmzZj00fTW1Hp0YCfMWy8fHx9HRsbGx8fr169rCZ5991srKqra29t69e6wD0ANjY2P6PDTTRou2TLGxsbrPOWZkZAwMDKxfv37YuOopB3OxBAIB/ZF0T3xCoXDlypXAR+fJGGGddFAoFDk5OTDiPDjV01dDcNAq0j9WSEiIbuFHH30EABERERwEoAcNDQ0AYGFhwWggFO0cDAgI0C2srq4GABsbGx5HsRoKLsSSSqUCgUAsFvfR+R4JIYTU19cDgLW19cDAAAcx6IGHhwcAnDt3jsXBaYv44Ycf6hbSR58TEhJY1MgxHI3H8vHxAYCSH09BNHfuXACoqKjgJobx8uqrrwLAW2+9xeLgp0+f3r59u276qr+/387ODgAm24ht/eBoBOlD8wtTIunAKLxVq1alpaXppq8KCgpaW1vnzZvn6+vLokaO4VSsqZXNWrZsmVgsvnTpUmtrKwfV0ZvEuLg4DuriAm4aRqVSaW5uLhAIdKcye2iHz6SCzhb5+eefs67osUlfaeGoxTI1NV2+fDkhpKSkRFsokUgCAwOHdfjwwokTJ/Ly8kaWc9amZmZmDgwMhISETPX0lRbulpULDg4uKCgoKirSTdKsWbOmrKysqKgoIiKCs0iGUVBQEBUVRQiprq6mD/Fpob3R6enpeXl5IpFo+vTpYrF4jBu6L3WvpR7K1B6F/DAEhKvlGW/cuPGLX/zC1ta2paXFyGiwpbx8+bKvr6+zszPNG3FPcXHxxo0bFQrFq6+++te//lX3ra6urtWrV1dVVQkEE/0rCYVCCwsLc3NzkUhkaWmp3ZBIJCKRSKFQpKamzpgx4/vvv9ed0nJKw51YAODm5nb79u3Kykp/f39aQghxcnJqbm6+du0azRtxSUlJSVhYmEKhSEhIOHLkiO5bDx48CA4OvnDhwpw5cwoLCx0cHORyeWdnp0Kh0G9j9EhcXV1FIlFNTQ3Lr8spnK6wunr16pSUlKKiIq1YtMMnIyOjqKiIY7HKy8vDw8PpJNiHDx/Wfau3tzc0NPTChQuzZ88uKyt78sknAWD69OmzZs3Sr66BgQGZTNbT0yOXy+mGQqHo6emhG01NTcnJyTKZLCMjY9u2bQb4bpMBLu8UvvzySwBYunSpbiF94GLt2rVcRlJeXk4nSN65c+ewB3J6e3uXL18OAC4uLkxHN+jy6aefAoC1tTXrlQo4g1Oxuru76U217sx09+/fNzIyGtbhw5R//etfdH2AuLi4kVbR5z6cnZ1vGnAyuDFAV+wJDQ3lslJ2cD3bzJIlS2DE3Cl0qGRxcTEHAVRUVFCrduzYMcyqvr4+OhDDwcFh7POXGoqmpib6GDQHaTMO4Fqsd955BwD27NmjW3jgwAEA2L9/P+vaq6ur6Z3/Cy+8MKzzW6lU0onz7O3ta2pqWEfyUD755BMAsLGxmaIPqerCtVgXLlwAgCeffFK3sKysDADmz5/PtOpLly7RcaEREREjrdqwYQO16urVq0zDGAWNRkNTspGRkXzFYCi4FkutVtM+/P/prKWsVCotLS39/f3ZPbdz+fJlatXmzZtHWhUWFgb8zTCoy507d+iZOmeKr7vKw1SRUVFRAPD3v/9dt7Cnp4ddjVeuXLGxsQGA8PDwYQP3+vv7N23aRO/IJsl4lQ8//BAAaCaZ71j0hwex6K01Z7c/tbW1Dg4OABASEjJsZKbuDIOVlZXcxPNINBoN7fyOjo7mOxb94UGsxsZGzqaRvX79Ou3WXbNmjVwu131LpVLFxMQAgJWV1WRbZKu+vp6m2XJzc/mORU/4mY573rx5AMB6YqO6ujq6PltwcPBIq2iO29LS8j//+Q/TMPQjOTkZAAIC/m+yDil6BPyI9frrr8OIiXsMy40bN2gPTFBQ0LDUq1qtplO7SCSSs2fPsothIqjV6p07S0QiEhvLdyh6wY9YdCipu7s7oz6Tmzdv0gW9VqxYMexOU6PRvPzyyzAV5oK7fZuYmxMAcvw436GMH37EysrKkkgkdMG0mTNn0nWU7hpuBfqOjg5/f//nnntu2M2mRqPZs2cPTJ254D74gACQmTOJzlMXUwMexMrJyREKhQCwYMECmgXQ4uHhsXfv3tzc3IkPVm5raxtp1d69ewFALBafOXNmgsfnBrWaLFlCAEhcHN+hjBOuxTp+/Didsvw3v/kNLbl161ZKSkpkZKTuhMFGRkaenp7x8fHZ2dkGWUtNo9Hs27cPAMzMzL766quJH5Azrl8nYjEBIKdO8R3KeOBUrK+//pqOkHz99ddHvqtSqbRrg4tEIq1k2gXoS0pKht3cjZ3ExEQAMDU1PXny5MS+BA+89x4BIE5ORGcS+MkOd2IVFhZSXV577bVHfrivr6+8vJxKpjurnVgsDgoK+v3vf19SUjL2h9/feOMNalVeXt7EvgQ/qNXkuecIAImP5zuUMcORWMXFxdSqV155Zbz7ymQy7drg2sHyAGBubh4UFJSUlFRVVaXRaH5q97feegsATExMptw6R7rU1hKRiAgEpLCQ71DGBhdinTt3TiKRAMDu3btHMWAs3L9/Pzs7OyEhYdhSPHZ2dpGRkYcPHx629tPBgwfpyfQxGOT0xz8SADJnDnnwgO9QxgDzhynOnz8fEhIik8leeumlTz75RCAQGOrIDQ0NpaWlZ86cKS0tbWpq0pbPmTNn5cqVK1euvHLlyvvvv29sbJyenk4XUJ3SqFQQGAiVlfCrX8E//mH44zc1NRUWFgqFQpFIFBAQ8M033wBAT0/P008/TfsuxwdTbS9evGiotmp06K1lbGys7vMO1tbWxsbGWVlZ7OrlmGvXiJkZEQgIi8G2PT09dEDRmTNnrly5QguPHz9+7949PY7G8CmdxsbGsrKyiIgIgUDw8ccfG7CtGomrq2t8fHx8fLxGo/nuu+9KS0tLS0vDw8NtbGzoqJjHAw8PePNNyMoCS0vDH5x2ewOAkZER/bHUanVzc7OLi4seR2N1KmxsbMzIyFAqld7e3mFhYboX3chEGBgAlQrEYlbH7+rqys7O3rVrl7Gx8Y0bN+rr69esWVNaWurv729hYTH21oHJ7y2VSrOyspRKpaenJ1o1ERwdoapq6KW/PxQVgVgMjo7g5QVq9WC5jw9McCU8eqGiVCpzc3M3bdpEp0WtqakRi8XFxcV9fX137tw5ceLEI5+81WL4U6FUKj169KhcLvf09NyyZQtaxYi+PkhNhV27Hv6uTAZdXdDdDd3dgxu2tlKx+KZCoVAoFEqlUvEDdHtgYCA+Pr6srGzZsmX29vYAoFarpVJpeHj4vXv3MjMzOzo6YmJiaF/cWDCwWC0tLdQqDw8PtIopb78Nv/sdxMQMnhaVSvD3h87OQY20jZmW115rsrI681NHEwgEdXV1jY2NKpWqoqJi4cKFZmZmrq6uNTU1HR0dfn5+bm5up06dCg4O1u0UGQVDitXW1paeni6Xy93d3dEqQxEWBtquh+bmoXJfX1iyBJKTITERAMDUFK5cAZVq8N1p08DaGqyswMpqcGPuXMe5c58TiUQikcjMzGzYBu3eoI+Aa3nqqafoRkVFhYODg5ub29jDNphY7e3taWlpvb297u7uW7du1Z27HJkI+fnww0wXQxuUQ4dg8WKIjwcAEAigshLMzQdNetja5E4ATvrFEBgYON5dDCNWe3t7amqqTCZzc3OLiopCq7jB1RWiouDddwdf+vjwGs2PMYBYcrk8LS2NWrV169axX98hE+fgQfDygkn4H9kAl0FisTggIGD27NlRUVFoFcfY2cG+fSCV8h3HCEZLkPb39x89erS1tXXHjh22trba7YdOE6XRaPBqHdEymgpCoTA6OtrLy2vY9sMPhFYhOoxmg5GREe1CHraNII9k3M0MPXWWlpY+ePCAUT8j8hgw7mvt+vr6mpqa/v7+O3fu3Lp1KyQkZIypWORnxbjFcnV1ValUenQeIT8rHjFsJjMzs6WlxdLS0sfHp66ujq7MYWdnN2PGDDc3t5qamrF3HiE/K/Qcj1VRUbFgwQLt0DAEGQanCwggPx8w+YQwAcVCmIBiIUxAsRAmoFgIE1AshAkoFsIEFAthAoqFMAHFQpiAYiFMQLEQJqBYCBNQLIQJKBbCBBQLYQKKhTABxUKYgGIhTECxECagWAgTUCyECSgWwgQUC2ECioUwAcVCmIBiIUxAsRAmoFgIE1AshAkoFsIEFAthAoqFMAHFQpiAYiFMQLEQJqBYCBNQLIQJKBbCBBQLYQKKhTABxUKYgGIhTECxECagWAgTUCyECSgWwoT/B/WkGx5pr/mWAAAAAElFTkSuQmCC\" alt=\"Mol\"/></td>\n",
       "      <td><img data-content=\"rdkit/molecule\" src=\"data:image/png;base64,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\" alt=\"Mol\"/></td>\n",
       "      <td>AAK1</td>\n",
       "      <td>NAK</td>\n",
       "      <td>Other</td>\n",
       "      <td>5l4q</td>\n",
       "      <td>LKB</td>\n",
       "      <td>B</td>\n",
       "      <td>A</td>\n",
       "      <td>AP AP AP AP AP AP AP AP AP AP AP AP AP AP AP F...</td>\n",
       "      <td>16 16 16 16 16 16 16 16 16 16 16 16 16 5 5 na na</td>\n",
       "      <td>Nc1c[nH]c2ncccc12</td>\n",
       "      <td>[11*]c1cnc2[nH]cc(N[27*])c2c1</td>\n",
       "      <td>AP</td>\n",
       "    </tr>\n",
       "    <tr>\n",
       "      <th>1</th>\n",
       "      <td><img data-content=\"rdkit/molecule\" src=\"data:image/png;base64,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\" alt=\"Mol\"/></td>\n",
       "      <td><img data-content=\"rdkit/molecule\" src=\"data:image/png;base64,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\" alt=\"Mol\"/></td>\n",
       "      <td><img data-content=\"rdkit/molecule\" src=\"data:image/png;base64,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\" alt=\"Mol\"/></td>\n",
       "      <td>AAK1</td>\n",
       "      <td>NAK</td>\n",
       "      <td>Other</td>\n",
       "      <td>5te0</td>\n",
       "      <td>XIN</td>\n",
       "      <td></td>\n",
       "      <td>A</td>\n",
       "      <td>AP AP AP AP AP AP AP AP AP AP AP AP AP AP AP A...</td>\n",
       "      <td>7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 ...</td>\n",
       "      <td>N/C(=C1\\C(=O)Nc2ccccc21)c1ccccc1</td>\n",
       "      <td>[12*]N/C(=C1\\C(=O)Nc2cc([20*])ccc21)c1ccccc1</td>\n",
       "      <td>AP</td>\n",
       "    </tr>\n",
       "  </tbody>\n",
       "</table>\n",
       "</div>"
      ],
      "text/plain": [
       "                                               ROMol  \\\n",
       "0  <img data-content=\"rdkit/molecule\" src=\"data:i...   \n",
       "1  <img data-content=\"rdkit/molecule\" src=\"data:i...   \n",
       "\n",
       "                                         ROMol_dummy  \\\n",
       "0  <img data-content=\"rdkit/molecule\" src=\"data:i...   \n",
       "1  <img data-content=\"rdkit/molecule\" src=\"data:i...   \n",
       "\n",
       "                                      ROMol_original kinase family  group  \\\n",
       "0  <img data-content=\"rdkit/molecule\" src=\"data:i...   AAK1    NAK  Other   \n",
       "1  <img data-content=\"rdkit/molecule\" src=\"data:i...   AAK1    NAK  Other   \n",
       "\n",
       "  complex_pdb ligand_pdb alt chain  \\\n",
       "0        5l4q        LKB   B     A   \n",
       "1        5te0        XIN         A   \n",
       "\n",
       "                                     atom_subpockets  \\\n",
       "0  AP AP AP AP AP AP AP AP AP AP AP AP AP AP AP F...   \n",
       "1  AP AP AP AP AP AP AP AP AP AP AP AP AP AP AP A...   \n",
       "\n",
       "                                   atom_environments  \\\n",
       "0   16 16 16 16 16 16 16 16 16 16 16 16 16 5 5 na na   \n",
       "1  7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 ...   \n",
       "\n",
       "                             smiles  \\\n",
       "0                 Nc1c[nH]c2ncccc12   \n",
       "1  N/C(=C1\\C(=O)Nc2ccccc21)c1ccccc1   \n",
       "\n",
       "                                   smiles_dummy subpocket  \n",
       "0                 [11*]c1cnc2[nH]cc(N[27*])c2c1        AP  \n",
       "1  [12*]N/C(=C1\\C(=O)Nc2cc([20*])ccc21)c1ccccc1        AP  "
      ]
     },
     "execution_count": 5,
     "metadata": {},
     "output_type": "execute_result"
    }
   ],
   "source": [
    "ap_fragments.head(2)"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {
    "slideshow": {
     "slide_type": "subslide"
    }
   },
   "source": [
    "### Draw AP fragment examples"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 6,
   "metadata": {
    "slideshow": {
     "slide_type": "-"
    }
   },
   "outputs": [],
   "source": [
    "ap_fragments_examples = ap_fragments[:5]\n",
    "legends = ap_fragments_examples[\"complex_pdb\"].to_list() \n",
    "mols_wo_dummy = ap_fragments_examples[\"ROMol\"].to_list()\n",
    "mols_w_dummy = ap_fragments_examples[\"ROMol_dummy\"].to_list()"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 7,
   "metadata": {
    "slideshow": {
     "slide_type": "-"
    }
   },
   "outputs": [
    {
     "data": {
      "image/png": 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\n",
      "text/plain": [
       "<PIL.PngImagePlugin.PngImageFile image mode=RGB size=1000x200 at 0x7F60A07DDDF0>"
      ]
     },
     "execution_count": 7,
     "metadata": {},
     "output_type": "execute_result"
    }
   ],
   "source": [
    "Draw.MolsToGridImage(mols=mols_wo_dummy, legends=legends, molsPerRow=5)"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 8,
   "metadata": {
    "slideshow": {
     "slide_type": "-"
    }
   },
   "outputs": [
    {
     "data": {
      "image/png": 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\n",
      "text/plain": [
       "<PIL.PngImagePlugin.PngImageFile image mode=RGB size=1000x200 at 0x7F61046315E0>"
      ]
     },
     "execution_count": 8,
     "metadata": {},
     "output_type": "execute_result"
    }
   ],
   "source": [
    "Draw.MolsToGridImage(mols=mols_w_dummy, molsPerRow=5)"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {
    "slideshow": {
     "slide_type": "slide"
    }
   },
   "source": [
    "## 2. View all fragments for Gefitinib (IRE)\n",
    "\n",
    "Investigate how different orientations/binding modes of the same molecules co-crystallized to different structures affect the subpocket assignment."
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {
    "slideshow": {
     "slide_type": "subslide"
    }
   },
   "source": [
    "### Find IRE fragments in each subpocket"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 9,
   "metadata": {
    "slideshow": {
     "slide_type": "-"
    }
   },
   "outputs": [
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      "Number of fragments from IRE ligands: 30\n"
     ]
    }
   ],
   "source": [
    "ire_fragments = get_fragments_by_ligand(\"IRE\", fragment_library)\n",
    "print(f\"Number of fragments from IRE ligands: {ire_fragments.shape[0]}\")"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 10,
   "metadata": {
    "slideshow": {
     "slide_type": "-"
    }
   },
   "outputs": [
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      "Kinases the ligand bind to:\n",
      "EGFR GAK\n"
     ]
    }
   ],
   "source": [
    "ire_kinases = ire_fragments[\"kinase\"].unique()\n",
    "print(\"Kinases the ligand bind to:\")\n",
    "print(*ire_kinases)"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 11,
   "metadata": {
    "slideshow": {
     "slide_type": "-"
    }
   },
   "outputs": [
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      "Ligand co-crystallized in structures with PDB IDs:\n",
      "2ito 2ity 2itz 3ug2 4i22 4wkq 5y7z 5y80\n"
     ]
    }
   ],
   "source": [
    "ire_pdbs = ire_fragments[\"complex_pdb\"].unique()\n",
    "print(\"Ligand co-crystallized in structures with PDB IDs:\")\n",
    "print(*ire_pdbs)"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {
    "slideshow": {
     "slide_type": "subslide"
    }
   },
   "source": [
    "### Draw example ligand fragmentation"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 12,
   "metadata": {
    "slideshow": {
     "slide_type": "-"
    }
   },
   "outputs": [
    {
     "data": {
      "image/png": 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BNjY2XC5XdaNoL9FfBtLHIOOYWCxms9lnzpyRSCRaVedwOH5+foh4QuMUZufOtQQFBVVWVgYEBJiamgoEgsbGRuId61X6uYRnzpzx9PSUSqVnzpzRrQUNb2bHjsGUKZYuLknTpgX7+/u/9957LBYrPT193rx52p5Xa3p7pDYUVVVVAGBjY0OSvHz00UfatiAUCkGz3Nl5eUiSDCxahALBEQAwMzM70DdrM/1nRvoYPB7Pycmpvr6ePOFpPjMsKyubPXt2Y2PjpEmTKIo6fvx4Xl6e+nH41i1obYXISGhuhi1bZs+YkZCfnx8WFtYD3dCEvrlSDALJnf3BBx8AwLBhwzSpUlRURPxQAoEgISGBxWKR9W7l+zfq6joP5f7uOwwORgDkcvH48R7tRnf0Zwk/+ugjAIiMjCQJQ6qqqtSXz8/PJ2/jmTt37ssvvwwApqamCxcu9PPzU75/IzDwMp+PKSl448bfFe/exXHjHjiYyst7t1OP058lLC4uBgAfH5/o6OjIyEj1CV9ycnLIIkB4ePj8+fMBwNLS8siRI+SvN2/e3L59+/TpM+zt5WRRlqLQzw9JgoG2Npw9G0ePxuvX+6BbHenPEkokEjMzMxaL1a3PLy0tjTgr1q1bR3JscbncTnNsNTTggQO4fPnfSa5IpJNYjCoL7H1Kf5ZQJpM5Ozubm5uPHTs2JSXlcWcTYcOGDQBAXhRCcmw5Ojp2u8Dd2opCIaam9mmkU6f0WwklEgkZD5WRuywWKyAgYMuWLR3SkOXl5ZmZmSUnJ48aNQoA3NzcNE/R2MeRTp3SPyVUjRwsKCggvkAytyR0CF87evTo8OHDAcDX17erOafR0g8llN+5MzkggIyH58+fVx5vbm4+ePBgeHi4jUq+dycnp/nz55OcjEFBQU1NTQa0XDdoIOG9e/e0eM+mSIQ+PpV8voe7e1eRgzKZrKioSCAQKMPXhg4dGhoaStP3Z9JAwszMTADw8vISCATqI3fx4kUcPhwBcNy41lu3NGm8tLQ0NTX12rVrRrVlUCtoIOHHH3+sGrk7cfx4jI7GH3/sGL52+jSSzQ2Bgah95CB9oYGE+HDoi46OdnZ2jgwMfBDyNGQIhodjbi6SH1BsLAJgaGiX6Yj7KT2QRq8vQcTms2etcnPh0CEoLwcAcHSEXbuAxYJbtwAAVqwATv/0Y3cFzSR8hCtX4JtvgM0GDgfeegs++QSiow1tkwGgs4RKDh4EU1O4dQs0fglkf6JfSPjPpt+6fP85MBLSHkZC2sNISHsYCWkPIyHtYSSkPYyEtIeRkPYwEtIeRkLaw0hIexgJaQ8jIe1hJKQ9jIS0h5GQ9jAS0h5GQtrDSEh76Cqhi4tLCXm77j8eo5awra1tzZo17u7ulpaWY8eOJVlECBs3buTxeADg7OyslZZjxozJyclRfqYoiqIoOzu7xYsXK99hqjxOCAkJ6bk+9TxGLaFUKqUoav/+/VVVVatWrVqwYEFFRQX5U3h4uOZ5tdSQlZXV3t5+6tSpyspK8jIYwp49e1ofQl6YZrQYtYQDBw5MS0vz8/MbOnRoVFTUiBEjlEmcyEC6atWq2traOXPmuLi47Nu3DwAqKiqmT5/O5XI9PT0PHDhACufm5n755ZednoLFYnE4HFdX13nz5p09e1Z53MTExPwhuuVS7DOMWkJVamtrq6qqSJJPJTt37nRwcBAKhVVVVeHh4XK5fM6cOQEBAXV1dRkZGStXriSqFBYWqn9LcHV19aFDh0aOHNm7feglDLopR1MkEklQUNDq1auVR3g83unTpxHRycmJfEDEU6dOcbnc9oeb1lauXLl+/foOTXl7e2dnZys/K7+HiRMn3nq4JdHb29vKysrmIRs3buzV3ukJDX6F7e3tCxYssLOzS01NVV+ypqbGycmJ83Bnk4uLi0gkUl8lOztboVCcOHGipqbmFtkbBQAAmzdv/v0hb731lp5d6FWMfR+XTCZbtGgRIn7++edsNvvxAsrk9gAwbNgwkUgkk8mIilVVVU5OTt2egqIof3//mJgYkkCBHORyuc7Ozj3Uid7FqH+Fcrl82bJljY2N2dnZcrlcIpHI5fIOZYYOHaqcpvr6+trb22/atKm9vb24uPjAgQNLliwBtdMZJZGRkeXl5T/++CP5b3t7u+QhbW1tPd2zHsXQI7k6KisrO1i7bds28iflvTA3N9fZ2dna2jojIwMRL1++PHXq1MGDB48aNeqLL74ghaOiopYuXUo+d7gXKj8jYnx8fGBgID56jwSAsWPH9k1/dYPZnEZ7jHogZdAERkLa8z+fGOC5MOVkqgAAAABJRU5ErkJggg==\n",
      "text/plain": [
       "<PIL.PngImagePlugin.PngImageFile image mode=RGB size=150x150 at 0x7F60A05E46D0>"
      ]
     },
     "execution_count": 12,
     "metadata": {},
     "output_type": "execute_result"
    }
   ],
   "source": [
    "draw_ligands_from_pdb_ids(\"2ito\", \"IRE\")"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 13,
   "metadata": {
    "slideshow": {
     "slide_type": "-"
    }
   },
   "outputs": [
    {
     "data": {
      "image/png": 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\n",
      "text/plain": [
       "<PIL.PngImagePlugin.PngImageFile image mode=RGB size=1000x200 at 0x7F60A052BD90>"
      ]
     },
     "execution_count": 13,
     "metadata": {},
     "output_type": "execute_result"
    }
   ],
   "source": [
    "draw_fragmented_ligand(\n",
    "    fragment_library, \"2ito\", \"IRE\", mols_per_row=5, include_dummy=True\n",
    ")"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {
    "slideshow": {
     "slide_type": "subslide"
    }
   },
   "source": [
    "### Compare IRE fragmentation in different complexes"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 14,
   "metadata": {
    "slideshow": {
     "slide_type": "-"
    }
   },
   "outputs": [
    {
     "data": {
      "image/png": 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\n",
      "text/plain": [
       "<PIL.PngImagePlugin.PngImageFile image mode=RGB size=1000x200 at 0x7F60A0543A00>"
      ]
     },
     "execution_count": 14,
     "metadata": {},
     "output_type": "execute_result"
    }
   ],
   "source": [
    "# Examples: 2ito, 2ity, 4i22, 4wkq, 5y80\n",
    "draw_fragmented_ligand(\n",
    "    fragment_library, \"2ito\", \"IRE\", mols_per_row=5, include_dummy=True\n",
    ")"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 15,
   "metadata": {
    "slideshow": {
     "slide_type": "-"
    }
   },
   "outputs": [
    {
     "data": {
      "image/png": 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\n",
      "text/plain": [
       "<PIL.PngImagePlugin.PngImageFile image mode=RGB size=1000x200 at 0x7F60A0543DC0>"
      ]
     },
     "execution_count": 15,
     "metadata": {},
     "output_type": "execute_result"
    }
   ],
   "source": [
    "# Example: 2itz\n",
    "draw_fragmented_ligand(\n",
    "    fragment_library, \"2itz\", \"IRE\", mols_per_row=5, include_dummy=True\n",
    ")"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {
    "slideshow": {
     "slide_type": "slide"
    }
   },
   "source": [
    "## 3. Identify most common fragments in the AP subpocket"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {
    "slideshow": {
     "slide_type": "subslide"
    }
   },
   "source": [
    "### Get most common AP fragments"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 16,
   "metadata": {
    "slideshow": {
     "slide_type": "-"
    }
   },
   "outputs": [],
   "source": [
    "most_common_fragments_df = get_most_common_fragments(ap_fragments, top_x=10)"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 17,
   "metadata": {
    "slideshow": {
     "slide_type": "-"
    }
   },
   "outputs": [
    {
     "data": {
      "image/png": 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\n",
      "text/plain": [
       "<PIL.PngImagePlugin.PngImageFile image mode=RGB size=1000x400 at 0x7F60A04EADF0>"
      ]
     },
     "execution_count": 17,
     "metadata": {},
     "output_type": "execute_result"
    }
   ],
   "source": [
    "mols = most_common_fragments_df[\"ROMol\"]\n",
    "legends = [f\"#{x}\" for x in most_common_fragments_df[\"fragment_count\"]]\n",
    "Draw.MolsToGridImage(mols=mols, legends=legends, molsPerRow=5)"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {
    "slideshow": {
     "slide_type": "subslide"
    }
   },
   "source": [
    "### Analyze the occurences of the most common AP fragment"
   ]
  },
  {
   "cell_type": "markdown",
   "metadata": {
    "slideshow": {
     "slide_type": "-"
    }
   },
   "source": [
    "Select the most common AP fragment."
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 18,
   "metadata": {
    "slideshow": {
     "slide_type": "-"
    }
   },
   "outputs": [
    {
     "data": {
      "image/png": "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\n",
      "text/plain": [
       "<rdkit.Chem.rdchem.Mol at 0x7f60a0544340>"
      ]
     },
     "execution_count": 18,
     "metadata": {},
     "output_type": "execute_result"
    }
   ],
   "source": [
    "query_mol = most_common_fragments_df[\"ROMol\"][0]\n",
    "query_mol"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 19,
   "metadata": {
    "slideshow": {
     "slide_type": "-"
    }
   },
   "outputs": [
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      "Number fragments: 103\n"
     ]
    }
   ],
   "source": [
    "ap_fragments_examples = ap_fragments[\n",
    "    ap_fragments[\"smiles\"] == Chem.MolToSmiles(query_mol)\n",
    "]\n",
    "print(f\"Number fragments: {ap_fragments_examples.shape[0]}\")"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 20,
   "metadata": {
    "slideshow": {
     "slide_type": "subslide"
    }
   },
   "outputs": [
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      "Example kinase-ligand complex:\n",
      "4dce 0JF\n"
     ]
    }
   ],
   "source": [
    "print(\"Example kinase-ligand complex:\")\n",
    "print(*ap_fragments_examples[[\"complex_pdb\", \"ligand_pdb\"]].iloc[0])"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 21,
   "metadata": {
    "slideshow": {
     "slide_type": "-"
    }
   },
   "outputs": [
    {
     "data": {
      "image/png": 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      "text/plain": [
       "<PIL.PngImagePlugin.PngImageFile image mode=RGB size=1200x200 at 0x7F60A0558820>"
      ]
     },
     "execution_count": 21,
     "metadata": {},
     "output_type": "execute_result"
    }
   ],
   "source": [
    "draw_fragmented_ligand(fragment_library, \"4dce\", \"0JF\", mols_per_row=6)"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 22,
   "metadata": {
    "slideshow": {
     "slide_type": "-"
    }
   },
   "outputs": [
    {
     "data": {
      "image/png": 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GLl68OCkpaevWrQcPHrx48WKDcXtZDWceP37cunXr2tranJwcZs/kSZMmbdmypUePHufPn+czGFew5tdff+3fv7+xsfGVK1fo0O8NzlYrePToUXV19c2bN728vCorKw0MDFRsQMrExMQsWrQoNDR00KBBU6dO9fT0vHjxolAoZHgNbO6mTz/9FMCoUaMYn4Hb4TUzpk2bpvqfy9LSksfjHTt27Pz5887Ozv/5z3/UrU4kEtHZa06ePEnPlLIMMc28FT59+tTV1VUsFl+9etXHx4fZSaDu8PrCBZw+/cIZsJGpA3URiUTHjh0LDw9XHoUpD8GUf6akpCxdutTR0XHv3r0BAQE1NTWHDx+m15aoSHx8/Lx583r27DllypRJkyZ5enrm5uayGtAxFn/BggXgKDbylClTAHTp0iU3N/fSpUuHDh3atm1bUlJS/rffklmzyEcfkSFDSM+epF07MnEiIYRkZZFf1I4bxAkURdGpGiZNmsQg80ZNTY2DgwOAw4cP00H8tm3bxtIkhhJWVFTQMUDUCt7TGM+fP7e3t3/1c9Vlf/+/rW0ASGgoIYRkZZEDB9jXy4z8/Hx6GUZqaiod+T8iIkLFsnSCgG7dum3fvh1AmzZtZKzD2TGU8MsvvwQwaNAgNnXX1tZ++OGHJ0+epCiqTZs2fD7f2dm5R48eQUFB9HjsSkICSUoiW7eSgwfJxYvk1i1y4sRfy1NEIja1syEhIQGAvb399evXVc+8IZFI6Af//v37O3XqBGDTpk3sjWEoYWRkJJ/PP378OCGkuLiYWVv87rvvAHh7e+/evRuAi4uLRPWQYPv2ETs7cvgwg3rZQ1GUv78/gHHjxikyb7wxAw2r620chhKOHz8ewJQpU3Jycpo3b96qVavKykq1ziCVSunZjd27d9Ojoe+++06N8itXEoA4OBB2GaAYc//+fUWqBlUyb7C93sZhKOGtW7fowKwHDx6kvzSpm+BRkf1s//79dKdUo1Z0SooiffoQgKj8HOKc//3vfwBsbGyuXr1Kd6eviQ4mk8k2b94cHBzM8Hobh/mIlF6T4ODgkJGRYWpqCuDQoUMqllVkP9u+ffu//vUvAEyWvefnE3NzAhCmGaBYIpfLAwMDAQwfPnzz5s1bt25VpVSvXr2gJV/tFcPriRMnxsfH03I+ffpUlbI//fQTPR47dOgQADs7O7FYzMSI1avlPN76oUOfPHnCpDhrioqK6ACZP//ccGxViUTyxx9/5OXlnT9//pdffomKimJ1vQ3Banbm1eG1KgkeFVnXNm/eTN8EzKdmKGr++PEAwsLCGJ6BNRs2bABgaWn53//+95NPPhk5cmTfvn29vb1dXFwa9Orz9fVdyenCMLbT3IrhtSKx3RsTPO7atYsej6mSde2NKDLQqJsBikOGDBny/vvvNzhzYmRkRKdS7dWr19ChQyMiIi5dusRt7WwlVB5eq5jgkX74JScn01nXvv76a5Y20IN1dTNAcQhFUenp6cuXL39jKtWmgIOv9srD6759+/J4vB9++OE1xz969Ojzzz+nF0lzEnZILpcPGDAA71ZiSdXhxv1p7dq1iuE1/b7/Rui0W19++SUnBhQWFvr7+9+4cYOTs+kW3Lg/EUKCgoKOHTsWEhJC+8XQSKXSBt0I7ty5s2vXLnNz84cPH75rKcrfOtxICODhw4edO3d+/vw5vf6KlqpeantlnJycDA0N7927p5Evve8SnEkIIDg4+MqVK2VlZYo9RkZGr35+EwqFAoFg1apVjx8/jo2NpT9a6WEOVz2yIgtEUlJSVlZWQUHB618VaM+fZs2avTO5kzQFZxIuW7YMQP/+/VUvMn36dABdu3Zl6Uj5D4cbCUUiER3t+syZM6qXqqqqcnNz83NyekwvV9HDCG4kjI+Lg9IqOtW5nZ4ut7QkRkYkK4sTS/6BcCGhWFzl5rbC3//0iRNMis+axTwVmh5uJExIIADp3p1hcToVGkA+/5wDY/55sJawtvbFApODB5mfRJFZUt+dqg/rZTGbNuHRI3TpgsGDmZ/E1xfz56NZM7w2e4+eBmH3ak9RaN0ahYVITcWIEWxtaQI3338C7FaF8fnYswczZyI0lANbzp3D559j9Gi8e8nNmhJGHWltLSgK2dkvGk18PMehsHQllqt20EBHWlFRcfLkSeXPC/1NTcNu3gSdjbC8HNXVmDYNLi747DMuI44fP46MDH1Hqi4NtML79++PHj1aeY91t25hSqGrYWICivrrJyeNJisLI0ZgzhzExHBwtn8SDUhob28/atQoa2trxeeFtu+9BwuLF7HGW7SAQAAAFy5wGXH8668hFmt1Rg9thcuPTczJy0OnTjA2Rn4+HBw0bY2O8bbjFDTMV1+9SHuh1099NN8KRb//bublxePzce8enJw0a4wuovlWODMmxsfd/XpUlF4/Zmi4Fd6/f79du3Y8Hu/OnTssw7j8Y9FwK4yNja2rq/voo4/0+jFGk62wqKjI3d2doqi8vDx6oZMeBmiyFa5Zs0YqlYaFhen1Y4MmW2FNTc33338/YMAAtUKg6amH5l8q9LBE8y8Veliil1Dn0Uuo8+gl1Hn0Euo8egl1Hr2EOo9eQp1HL6HOo5dQ59FLqPPoJdR5dFjCqKgofagFaLmEBQUFAoGADjLUFFRVVYWFhdHp3ZQTaHXs2JGO1Uhv85S4du1aExnDGA5yNjUdkZGRbNInvJFPP/20rKysoKDg9u3bgwcP9vLyoiMz1uOHH36gsxUCaCwpowbR3laYlpbG4/GGDBmivDMvL6979+5WVlZDhw599uyZYn9JScmYMWPs7Oysra0VKa5LS0tHjx793nvvubq60hEbAaSmpqakpACQyWQpKSlLliyxtbXt3bv3mDFjfvzxxwYtMTIyMnkJx/nMuUBLJRSLxdHR0YmJico7KYoKDQ0NDQ0tLy+fNWuWoq+Ty+UhISHW1tb37t0rKSmZNGkSAEJIaGioi4tLYWHh2bNnk5OT6fC1J06coDcKCgrEYjEdqwovs2S8xUvkDo2tL34t8+fPX7JkCSEkNjY2MDCQ3nnlyhVra2tF8tTBgwdHR0cTQjIzM62srGpr/5aJMDs729LSUnHw6tWrJ/w9DXNmZiYARSbTrVu3enl50dteXl6KDCBeXl7m5ubW1tbW1tZ+fn5NcK1s0cZnYV5eXlpa2o0bN+rtLykpcXFxUcRsa926Nb1RVFTk5ORU7yn18OFDiUTi9XLlt1QqVTQ4GjoAblVVlaWlJYDKysrGEmjFxMSEhoYCoLPVaxvaKOG5c+eKi4tdXV0BiMViqVTq6upaUFDg4OCgHOCttLSUVtHZ2bm4uFgqlRobGyv+19nZuXnz5rdu3Wrs6eXq6ioQCHJycvz8/ADcuHHDq5GV/kKh0EmLPc218Vk4YcKE/Pz87Ozs7Ozs2bNn+/r6XrlyBYCPj4+pqenevXsB3L17l36kAejSpUvbtm3nzp1LZwRMT08H4O3t7ebmFh0dLRKJaFfVjIwMKA1njIyMwsPDly1bVlFRcfny5V27dtGJrnUObZTQ1NS05UvMzc2NjY3t7OwA8Pn8ffv2rVy50s/Pb+HChR9++CF9PI/HS0tLKykpcXV1dXBw2LJlCwADAwN6p7u7u42Nzccff0yPYBXDGQAJCQl0CxsxYsSKFSuU3yi0cOTZGHonxAZwdnbeuHFj000pcIs2Pgs1iFQqPXHiRFlZmbe3t6ZtUZX/A3/SWOYYS092AAAAAElFTkSuQmCC\n",
      "text/plain": [
       "<PIL.PngImagePlugin.PngImageFile image mode=RGB size=150x150 at 0x7F60A04EAAC0>"
      ]
     },
     "execution_count": 22,
     "metadata": {},
     "output_type": "execute_result"
    }
   ],
   "source": [
    "draw_ligands_from_pdb_ids(\"4dce\", \"0JF\")"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 23,
   "metadata": {
    "slideshow": {
     "slide_type": "subslide"
    }
   },
   "outputs": [
    {
     "name": "stdout",
     "output_type": "stream",
     "text": [
      "Example kinase-ligand complex:\n",
      "4xv2 P06\n"
     ]
    }
   ],
   "source": [
    "print(\"Example kinase-ligand complex:\")\n",
    "print(*ap_fragments_examples[[\"complex_pdb\", \"ligand_pdb\"]].iloc[3])\n",
    "# Dabrafenib"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 24,
   "metadata": {
    "slideshow": {
     "slide_type": "-"
    }
   },
   "outputs": [
    {
     "data": {
      "image/png": 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\n",
      "text/plain": [
       "<PIL.PngImagePlugin.PngImageFile image mode=RGB size=1200x200 at 0x7F60A05CE400>"
      ]
     },
     "execution_count": 24,
     "metadata": {},
     "output_type": "execute_result"
    }
   ],
   "source": [
    "draw_fragmented_ligand(fragment_library, \"4xv2\", \"P06\", mols_per_row=6)"
   ]
  },
  {
   "cell_type": "code",
   "execution_count": 25,
   "metadata": {
    "slideshow": {
     "slide_type": "-"
    }
   },
   "outputs": [
    {
     "data": {
      "image/png": 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7JhQK8ZAJHa4lFRUVPdZlNBrFYrF5ODx48ODq1avNRy9evGjp0xYTEyORSPCacGNjo3k1bvnyN23vU43Gh1rtbwrF/zU0nDQYHly/7lNRkarTFfeYsaSkZOTIkfBnt4H09HR8srm5uUKh0NKVJDMz07pzaZ9IiK/NlpZrJSVTVKrPekz/zTff4Ony2LFjTSbT5MmTAWDx4sX2jlK5ubnY8SI4OPjixYt6vV4ikeBBCE98EhMTu5x/SiQSFos1efLt4cPRb7/1UItOV1JZKbp61b24OBohpNH8qFZ/bTLZ4Udp6Tbw17/+taGhoa6ubt++fePHjzdP1hITE8+ePWtLaX0iIb42ETIh1MVo1CUtLS3r16/Pz89HCOEmWFJS0ouqzZ0qjUYzP7wODAx89913O/vRWHLjhiwsDAEgDw+0b18XCdraUG5uW2npTIs+c/bDh3trarY0NJzSaM7V1XWKk2WV/fv3Y7cBPz8/c5/p6+u7YcMGuybJfdWR4muzFxnv378PAD4+Pr12zjcajW+99ZanpyeTybTsM3ukqQktWvS7H7pQiMxzkcZGlJGBBg1CAOjnn5OuXRtQUZGq091CCLW3a2trd9fX50qlUFTEf+TuokdKS0uHDh2KZ3ajRo3KzMzsxfS4TySsqztUU7Olvv6kXm+TM6sl2dnZeDxzxID8/HwAGDFiRC/yfvUVYrGQuztavBjl56OUFOTu/ruuQ4ag48er29oazYkrKpZKpVBd/XZxcaxUCmr1Xnur2759O+5Oe2Eqpk8esHE4r3l7L6iq+ntZ2V8A7HsQWlqq5fP9xzkWNBg/UcQeRPayZAnk50N2NkRHQ14ehIRAaytMnAg5OXD7NsyZE0ijeZoT83jLAKC2djePlwIAtcpP7a0O++GZp9+9oK+ekTIYgygURmtrWWPjabsyfvddilJZM2HCW47U7siaAACEh8OcOQAAXC60t4NMBpcuQWIidHJbARYrxt19XHt7PSDT4POzw15WwS+/9Kep0HcSUig0Hu/vAKBSfWx7rpYWKCoCOh1iY10cqb03SxBdkZAAly9Dh6d/1wSw1gz/bIrPHAmnPppSLoNPPrGriidXQgDgclOoVHeN5oxef9vGLPn50NYGUVFguyNEl7Dj4uLffTcsJsaRQlasAFdXOHOmh2Se/nPdfiin5F2ByEhgMODIEaiqsr2WkL/8JXrOnBAHdsX2oYQ0mpePj7Cuzv/YsRwbs1y+DADQcXfUe8qHDKmZNeuZ0aMdKcQyxrw1XFwgNRUA4MABSEgAb28oKbGxCiNCFQKBy6ZNAR0PRXtBX+8NX/XSS18xmdtnz17NZrNLSkpqamrkcrlKpaqv/7tM5lpbCzU1cPQo4EW0+/cBiJBQYTAAgL9jkQssY8z3wLJlsHUrVFfD0aPA40HH3pceURgMJgA/Fxeq/b4Hf9DruayN4F10H374IULIcoo4bNjv8dcB0MWLf6RXKJCDG8f07e2xUun4wkIHN31bxpjvGfyg/Kef0AcfoPfft7GKfI0mRipdWlraC/PM9HmEhpUrV/74448ff/yxSCQaN25cYGBgQECAr69vaGgTi+XGYACNBrW1sHcvXLsGixbBlSuwYoVDNSoMBgTAZzAcuLDtZ8gQgA4v0wMHoKamh1kQAHT0Fn6O9RZ9LqFAIAgNDS0vL1+6dCmPxwMAuVx+48aNkpIVP/zga5lywwbIywOqw6NzS3t7AIMRZHNv1h2rV//xaSt2epnWt7XBky8hlUodO3asTqfbs2eP5e9crppGe9bXF3x9ISAAeDyg0YDLhTt3HK1xuLt7bsej7f4Ge5kiZEsTBIDX+fwkHs/o2Dtz+vydTXV1dWFhYWq1Oj4+fsqUKXw+n8/n+/v7+/qG8Hhsyza3cyekpMDLL/c8j7fOYwzEZC+EmNrnrXDjxo1qtXratGm5ubnWU+Ih0EH9zDyWQEy9w1FTHZkL9cjVq1dpNBqdTic8rIwVsm0O+PLYIcRUuycPCKFt27bZ4k6PEFq9enV7e/uqVatGPK7B6WnA7gsnOxsAvLy8MjIyunRrNCORSACAz+dbD59D4iB2S1hWVvbSSy9h+SMjI7vzStJoNHglk5DICCRW6OVYmJuba3YsFwgEeJOKJf/4xz8AYMKECYRHxiN5hN5PZ7RabXp6OvZPcXd3F4vFev3vbge3bt1ycXGh0WjXrl0jxkyS7nF0RlpVVYXdBgFg6NCh33//PUJo2rRpALB8+XIiLCTpAWJuKk6fPj106FAs5NixYwHA29tbrVYTUjiJdQi7LzQYDBkZGR4eHhQKhUqlxsfH9yI6KkkvIPjWfoXFKsOzzz777bffEls+SWeIlLCsrIzJZFKp1F27dpnv5WfMmIHDSZL0EURKOHv2bABISUlBCBmNxoyMDBznhsFgiESifggB+nRCmITHjh0DAA6HY+n3rlarRSIR3q0SGBgokUiIqo7EDDESarXaQYMGAcAnn3zS+WhBQQGepgJAXFxcPwTIfqogRkKxWAwAERER3T01bWtr++yzz/BeTgaD8emnnxJSLwkiREKZTMZisSgUys8//2w9ZV1dnUgkotPpVvZ7ktgLARLOnTsXABYtWmRjelu2fJLYjqOOF2fPnn3xxRcHDBhQUlISYJvDCAmxOOQvZjAYVq5cCQBisZjU73HhUCu8fPnyCy+8MHDgwKKiIvP2cJJ+xtGOtLKyUq1WR0dHE2UQib30uRMiSV/zGIJZkhALKaHTQ0ro9JASOj2khE4PKaHTQ0ro9JASOj2khE4PKaHTQ0ro9JASOj2khE4PKaHTQ0ro9JASOj2khE4PKaHT84RKWFFRwWKxzG8hsR2DwbBixYrQ0FAWixUZGdldvKKIiAgKhUKhUHg83oIFC/C7KJuampKSktzd3YOCgj7//HPL9FlZWWFhYUwmMywsrKCgoHcn1Vc8XjfW7hAIBJMmTZo5c6a9GTUazYoVKwoKCpRK5eeff85kMsvKyjonCw8Pl0gkRqPxzp07o0aNSk1NRQilpKTExcWpVKoLFy54eHiYXc5PnjzJ5/Nzc3OVSmVBQcH9+/cdOzmCeRIlPHbsWHx8/HvvvWeW8O7duxwOp7CwECH04MEDHx+fc+fOvffee5bvBhCJRCtXrnykqCFDhhw+fBh///e//21+MVN4ePi+jheKpKenjx071mAwuLu7nz9/Hv+YnJycnJyMv48aNWrPnj19caaE8MR1pC0tLWlpaRl/jqccGhr6/vvvL1y4UKvVLl68+G9/+9vUqVPnz59/6tQpjUYDAO3t7Tk5OQsWLLDMpVAoKioqzJtVz549+9133z1SXXNzMw4UUFFR0dLSEhUVhX+Pioq6desWALS2tl6/fl2hUAQGBvr7+4tEIr1e3ydn3mse9zX0KG+//fbmzZsRQpatEBMfHx8RETFixAhzdJSJEyfiPYtnzpwZPHiwZWK9Xj916tTuom6Eh4ez2Ww+n89kMqdOnVpdXX316lUAMEfJycrKCg8PRx2vf5w0aZJCoaisrBw5cuSmTZuIPmmHeLJaYXFx8fHjx9PS0ro8unTp0ps3b65cuZLZES52wYIFBw8eBIADBw5YNkGj0Thv3jwej7djx47u6vrXv/5VVFSk0WjOnTsXGBiIA+g0NTXho42NjfiFSviFgm+++Safzw8ODhaJRKdOnSLmbInicV9Df2LXrl0sFgvHLPXw8GAwGOa3nzY1NQ0ePDg5OTkgIMD8qleVSuXq6lpVVcVms4uLf3/xnNFoTEhIiI+Pt/KqJsuxEGMwGFgs1sWOMOEpKSnmsZDL5Z44cQJ///LLL2NjYwk7YSJ4siTUarXyDtavXx8XF2d+U/OSJUsSExMRQkuXLsVfMLNmzZoxY0ZUVBT+s62t7bXXXouLi2toaNDpdDqdrq2tDR/qbjpjJjk5+YUXXqirq8vLy/P09DTPSN96663JkyfX1tY+ePAgKioK9/NPDk+WhJZYjoXHjx83N76mpqbQ0ND9+/fjQ1lZWQCwbds2/Cd+8ZolH3XEuF+2bNnChQvx9y4l1Gg08+bNY7FY/v7+u3btMv+u1+tTUlI8PT35fP6qVavMI/ETArmnwul5sqYzJL2AlNDpISV0ev4fmekyUM91D7sAAAAASUVORK5CYII=\n",
      "text/plain": [
       "<PIL.PngImagePlugin.PngImageFile image mode=RGB size=150x150 at 0x7F60A051BFD0>"
      ]
     },
     "execution_count": 25,
     "metadata": {},
     "output_type": "execute_result"
    }
   ],
   "source": [
    "draw_ligands_from_pdb_ids(\"4xv2\", \"P06\")  "
   ]
  },
  {
   "attachments": {
    "image.png": {
     "image/png": 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"
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    "## Acknowledgements\n",
    "\n",
    "![image.png](attachment:image.png)\n",
    "\n",
    "\n",
    "## Thank you for your attention!"
   ]
  }
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