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@fonnesbeck
Created March 25, 2016 17:04
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{
"cells": [
{
"cell_type": "code",
"execution_count": 1,
"metadata": {
"collapsed": true
},
"outputs": [],
"source": [
"import numpy as np"
]
},
{
"cell_type": "code",
"execution_count": 3,
"metadata": {
"collapsed": true
},
"outputs": [],
"source": [
"treat = 330.8\n",
"treat_se = 99.7\n",
"\n",
"placebo = 188.1\n",
"placebo_se = 55.5\n",
"\n",
"n = 15"
]
},
{
"cell_type": "markdown",
"metadata": {},
"source": [
"Formula for SE of difference:\n",
"\n",
"$$SE = \\sqrt{\\frac{SD_T^2}{n_T} + \\frac{SD_C^2}{n_C}}$$\n",
"\n",
"and $SE = SD/\\sqrt{n}$, so for this example:\n",
"\n",
"$$SE = \\sqrt{SE_T^2 + SE_C^2}$$"
]
},
{
"cell_type": "code",
"execution_count": 6,
"metadata": {
"collapsed": false
},
"outputs": [
{
"data": {
"text/plain": [
"114.10670444807351"
]
},
"execution_count": 6,
"metadata": {},
"output_type": "execute_result"
}
],
"source": [
"SE_diff = np.sqrt(99.7**2 + 55.5**2)\n",
"SE_diff"
]
},
{
"cell_type": "markdown",
"metadata": {},
"source": [
"Hence, a 95% confidence interval for the difference would be:"
]
},
{
"cell_type": "code",
"execution_count": 7,
"metadata": {
"collapsed": false
},
"outputs": [
{
"data": {
"text/plain": [
"(-85.513408896147013, 370.91340889614708)"
]
},
"execution_count": 7,
"metadata": {},
"output_type": "execute_result"
}
],
"source": [
"d = treat-placebo\n",
"d - 2*SE_diff, d + 2*SE_diff"
]
},
{
"cell_type": "markdown",
"metadata": {},
"source": [
"Which, given n=15 and the variability, is pretty unccertain."
]
}
],
"metadata": {
"kernelspec": {
"display_name": "Python 3",
"language": "python",
"name": "python3"
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"codemirror_mode": {
"name": "ipython",
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"file_extension": ".py",
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"name": "python",
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"pygments_lexer": "ipython3",
"version": "3.5.1"
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"nbformat_minor": 1
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