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inodb/hotspots_categories.ipynb

Last active April 4, 2018 21:41
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hotspots_categories.ipynb
{
"cells": [
{
"cell_type": "code",
"execution_count": 61,
"metadata": {},
"outputs": [],
"source": [
"import pandas as pd\n",
"import numpy as np\n",
"import re\n",
"import hgvs # https://github.com/biocommons/hgvs"
]
},
{
"cell_type": "code",
"execution_count": 62,
"metadata": {
"collapsed": true
},
"outputs": [],
"source": [
"h = pd.read_csv('hotspots_table_from_website.txt', sep=\"\\t\")"
]
},
{
"cell_type": "code",
"execution_count": 63,
"metadata": {},
"outputs": [
{
"data": {
"text/html": [
"<div>\n",
"<style scoped>\n",
" .dataframe tbody tr th:only-of-type {\n",
" vertical-align: middle;\n",
" }\n",
"\n",
" .dataframe tbody tr th {\n",
" vertical-align: top;\n",
" }\n",
"\n",
" .dataframe thead th {\n",
" text-align: right;\n",
" }\n",
"</style>\n",
"<table border=\"1\" class=\"dataframe\">\n",
" <thead>\n",
" <tr style=\"text-align: right;\">\n",
" <th></th>\n",
" <th>Gene</th>\n",
" <th>Residue</th>\n",
" <th>Type</th>\n",
" <th>Variants</th>\n",
" <th>Q-value</th>\n",
" <th>Samples</th>\n",
" <th>Tumor Type Composition</th>\n",
" </tr>\n",
" </thead>\n",
" <tbody>\n",
" <tr>\n",
" <th>0</th>\n",
" <td>NRAS</td>\n",
" <td>Q61</td>\n",
" <td>single residue</td>\n",
" <td>R:204|K:142|L:46|H:27|P:2|*:1</td>\n",
" <td>0.0</td>\n",
" <td>422</td>\n",
" <td>skin:187|thyroid:71|blood:37|bowel:35|lung:17|...</td>\n",
" </tr>\n",
" <tr>\n",
" <th>1</th>\n",
" <td>PIK3CA</td>\n",
" <td>E545</td>\n",
" <td>single residue</td>\n",
" <td>K:575|G:21|Q:20|A:12|D:5</td>\n",
" <td>0.0</td>\n",
" <td>633</td>\n",
" <td>breast:174|bowel:97|bladder:90|lung:51|head_ne...</td>\n",
" </tr>\n",
" <tr>\n",
" <th>2</th>\n",
" <td>IDH1</td>\n",
" <td>R132</td>\n",
" <td>single residue</td>\n",
" <td>H:570|C:139|G:28|S:16|L:12|I:1</td>\n",
" <td>0.0</td>\n",
" <td>766</td>\n",
" <td>brain:612|biliary_tract:57|skin:25|blood:23|pr...</td>\n",
" </tr>\n",
" <tr>\n",
" <th>3</th>\n",
" <td>PIK3CA</td>\n",
" <td>H1047</td>\n",
" <td>single residue</td>\n",
" <td>R:537|L:85|Y:18|Q:7</td>\n",
" <td>0.0</td>\n",
" <td>647</td>\n",
" <td>breast:361|bowel:54|uterus:51|stomach:28|brain...</td>\n",
" </tr>\n",
" <tr>\n",
" <th>4</th>\n",
" <td>BRAF</td>\n",
" <td>V600</td>\n",
" <td>single residue</td>\n",
" <td>E:833|M:29|K:24|R:4|V:4|G:3</td>\n",
" <td>0.0</td>\n",
" <td>897</td>\n",
" <td>skin:357|thyroid:316|bowel:113|lung:33|unk:21|...</td>\n",
" </tr>\n",
" </tbody>\n",
"</table>\n",
"</div>"
],
"text/plain": [
" Gene Residue Type Variants Q-value \\\n",
"0 NRAS Q61 single residue R:204|K:142|L:46|H:27|P:2|*:1 0.0 \n",
"1 PIK3CA E545 single residue K:575|G:21|Q:20|A:12|D:5 0.0 \n",
"2 IDH1 R132 single residue H:570|C:139|G:28|S:16|L:12|I:1 0.0 \n",
"3 PIK3CA H1047 single residue R:537|L:85|Y:18|Q:7 0.0 \n",
"4 BRAF V600 single residue E:833|M:29|K:24|R:4|V:4|G:3 0.0 \n",
"\n",
" Samples Tumor Type Composition \n",
"0 422 skin:187|thyroid:71|blood:37|bowel:35|lung:17|... \n",
"1 633 breast:174|bowel:97|bladder:90|lung:51|head_ne... \n",
"2 766 brain:612|biliary_tract:57|skin:25|blood:23|pr... \n",
"3 647 breast:361|bowel:54|uterus:51|stomach:28|brain... \n",
"4 897 skin:357|thyroid:316|bowel:113|lung:33|unk:21|... "
]
},
"execution_count": 63,
"metadata": {},
"output_type": "execute_result"
}
],
"source": [
"h.head()"
]
},
{
"cell_type": "code",
"execution_count": 64,
"metadata": {},
"outputs": [
{
"data": {
"text/plain": [
"1165"
]
},
"execution_count": 64,
"metadata": {},
"output_type": "execute_result"
}
],
"source": [
"len(h)"
]
},
{
"cell_type": "code",
"execution_count": 65,
"metadata": {},
"outputs": [
{
"data": {
"text/html": [
"<div>\n",
"<style scoped>\n",
" .dataframe tbody tr th:only-of-type {\n",
" vertical-align: middle;\n",
" }\n",
"\n",
" .dataframe tbody tr th {\n",
" vertical-align: top;\n",
" }\n",
"\n",
" .dataframe thead th {\n",
" text-align: right;\n",
" }\n",
"</style>\n",
"<table border=\"1\" class=\"dataframe\">\n",
" <thead>\n",
" <tr style=\"text-align: right;\">\n",
" <th></th>\n",
" <th>Gene</th>\n",
" <th>Residue</th>\n",
" <th>Type</th>\n",
" <th>Variants</th>\n",
" <th>Q-value</th>\n",
" <th>Samples</th>\n",
" <th>Tumor Type Composition</th>\n",
" </tr>\n",
" </thead>\n",
" <tbody>\n",
" <tr>\n",
" <th>0</th>\n",
" <td>NRAS</td>\n",
" <td>Q61</td>\n",
" <td>single residue</td>\n",
" <td>R:204|K:142|L:46|H:27|P:2|*:1</td>\n",
" <td>0.0</td>\n",
" <td>422</td>\n",
" <td>skin:187|thyroid:71|blood:37|bowel:35|lung:17|...</td>\n",
" </tr>\n",
" <tr>\n",
" <th>1</th>\n",
" <td>PIK3CA</td>\n",
" <td>E545</td>\n",
" <td>single residue</td>\n",
" <td>K:575|G:21|Q:20|A:12|D:5</td>\n",
" <td>0.0</td>\n",
" <td>633</td>\n",
" <td>breast:174|bowel:97|bladder:90|lung:51|head_ne...</td>\n",
" </tr>\n",
" <tr>\n",
" <th>2</th>\n",
" <td>IDH1</td>\n",
" <td>R132</td>\n",
" <td>single residue</td>\n",
" <td>H:570|C:139|G:28|S:16|L:12|I:1</td>\n",
" <td>0.0</td>\n",
" <td>766</td>\n",
" <td>brain:612|biliary_tract:57|skin:25|blood:23|pr...</td>\n",
" </tr>\n",
" <tr>\n",
" <th>3</th>\n",
" <td>PIK3CA</td>\n",
" <td>H1047</td>\n",
" <td>single residue</td>\n",
" <td>R:537|L:85|Y:18|Q:7</td>\n",
" <td>0.0</td>\n",
" <td>647</td>\n",
" <td>breast:361|bowel:54|uterus:51|stomach:28|brain...</td>\n",
" </tr>\n",
" <tr>\n",
" <th>4</th>\n",
" <td>BRAF</td>\n",
" <td>V600</td>\n",
" <td>single residue</td>\n",
" <td>E:833|M:29|K:24|R:4|V:4|G:3</td>\n",
" <td>0.0</td>\n",
" <td>897</td>\n",
" <td>skin:357|thyroid:316|bowel:113|lung:33|unk:21|...</td>\n",
" </tr>\n",
" </tbody>\n",
"</table>\n",
"</div>"
],
"text/plain": [
" Gene Residue Type Variants Q-value \\\n",
"0 NRAS Q61 single residue R:204|K:142|L:46|H:27|P:2|*:1 0.0 \n",
"1 PIK3CA E545 single residue K:575|G:21|Q:20|A:12|D:5 0.0 \n",
"2 IDH1 R132 single residue H:570|C:139|G:28|S:16|L:12|I:1 0.0 \n",
"3 PIK3CA H1047 single residue R:537|L:85|Y:18|Q:7 0.0 \n",
"4 BRAF V600 single residue E:833|M:29|K:24|R:4|V:4|G:3 0.0 \n",
"\n",
" Samples Tumor Type Composition \n",
"0 422 skin:187|thyroid:71|blood:37|bowel:35|lung:17|... \n",
"1 633 breast:174|bowel:97|bladder:90|lung:51|head_ne... \n",
"2 766 brain:612|biliary_tract:57|skin:25|blood:23|pr... \n",
"3 647 breast:361|bowel:54|uterus:51|stomach:28|brain... \n",
"4 897 skin:357|thyroid:316|bowel:113|lung:33|unk:21|... "
]
},
"execution_count": 65,
"metadata": {},
"output_type": "execute_result"
}
],
"source": [
"h.head()"
]
},
{
"cell_type": "code",
"execution_count": 66,
"metadata": {},
"outputs": [
{
"data": {
"text/plain": [
"array(['single residue', 'in-frame indel'], dtype=object)"
]
},
"execution_count": 66,
"metadata": {},
"output_type": "execute_result"
}
],
"source": [
"h.Type.unique()"
]
},
{
"cell_type": "code",
"execution_count": 67,
"metadata": {},
"outputs": [],
"source": [
"import hgvs.parser\n",
"PARSER = hgvs.parser.Parser()\n",
"\n",
"def count_variant_types(row):\n",
" MISSENSE_INDEX = 0\n",
" TRUNC_INDEX = 1\n",
" # FS_INDEX = 2\n",
" INFRAME_INDEX = 2\n",
" SPLICE_INDEX = 3\n",
" TOTAL_INDEX = 4\n",
" INDEX_NAMES = \"missense trunc inframe splice total\".split()\n",
" rv = [0, 0, 0, 0, 0]\n",
" \n",
" for v in row.Variants.split(\"|\"):\n",
" # add total\n",
" rv[TOTAL_INDEX] += int(v.split(\":\")[1])\n",
" \n",
" if \"*\" in v:\n",
" rv[TRUNC_INDEX] += int(v.split(\":\")[1])\n",
" elif \"sp\" in v:\n",
" rv[SPLICE_INDEX] += int(v.split(\":\")[1])\n",
" else:\n",
" # parse hgvs to get protein change length (can always use TP53, don't care about which protein)\n",
" if row.Type == \"in-frame indel\":\n",
" sv = PARSER.parse_hgvs_variant(\"TP53:p.{}\".format(v.split(\":\")[0]))\n",
" elif row.Type == \"single residue\":\n",
" sv = PARSER.parse_hgvs_variant(\"TP53:p.{}{}\".format(row.Residue, v.split(\":\")[0]))\n",
" else:\n",
" raise(Exception(\"unknown Type: {}\".format(row.Type)))\n",
" \n",
" if sv.posedit.pos.start == sv.posedit.pos.end and sv.posedit.length_change() == 0:\n",
" rv[MISSENSE_INDEX] += int(v.split(\":\")[1])\n",
" else:\n",
" rv[INFRAME_INDEX] += int(v.split(\":\")[1])\n",
" \n",
" return pd.Series(rv, index=INDEX_NAMES)"
]
},
{
"cell_type": "code",
"execution_count": 68,
"metadata": {},
"outputs": [],
"source": [
"h_counts = h.apply(count_variant_types, axis=1)"
]
},
{
"cell_type": "code",
"execution_count": 69,
"metadata": {
"collapsed": true
},
"outputs": [],
"source": [
"for c in h_counts.columns:\n",
" h[c + \"_count\"] = h_counts[c]\n",
"for c in h_counts.columns[:-1]:\n",
" h[c+\"_fraction\"] = h_counts[c] / h_counts[\"total\"]"
]
},
{
"cell_type": "code",
"execution_count": 70,
"metadata": {},
"outputs": [
{
"data": {
"text/html": [
"<div>\n",
"<style scoped>\n",
" .dataframe tbody tr th:only-of-type {\n",
" vertical-align: middle;\n",
" }\n",
"\n",
" .dataframe tbody tr th {\n",
" vertical-align: top;\n",
" }\n",
"\n",
" .dataframe thead th {\n",
" text-align: right;\n",
" }\n",
"</style>\n",
"<table border=\"1\" class=\"dataframe\">\n",
" <thead>\n",
" <tr style=\"text-align: right;\">\n",
" <th></th>\n",
" <th>Gene</th>\n",
" <th>Residue</th>\n",
" <th>Type</th>\n",
" <th>Variants</th>\n",
" <th>Q-value</th>\n",
" <th>Samples</th>\n",
" <th>Tumor Type Composition</th>\n",
" <th>missense_count</th>\n",
" <th>trunc_count</th>\n",
" <th>inframe_count</th>\n",
" <th>splice_count</th>\n",
" <th>total_count</th>\n",
" <th>missense_fraction</th>\n",
" <th>trunc_fraction</th>\n",
" <th>inframe_fraction</th>\n",
" <th>splice_fraction</th>\n",
" </tr>\n",
" </thead>\n",
" <tbody>\n",
" <tr>\n",
" <th>0</th>\n",
" <td>NRAS</td>\n",
" <td>Q61</td>\n",
" <td>single residue</td>\n",
" <td>R:204|K:142|L:46|H:27|P:2|*:1</td>\n",
" <td>0.0</td>\n",
" <td>422</td>\n",
" <td>skin:187|thyroid:71|blood:37|bowel:35|lung:17|...</td>\n",
" <td>421</td>\n",
" <td>1</td>\n",
" <td>0</td>\n",
" <td>0</td>\n",
" <td>422</td>\n",
" <td>0.99763</td>\n",
" <td>0.00237</td>\n",
" <td>0.0</td>\n",
" <td>0.0</td>\n",
" </tr>\n",
" <tr>\n",
" <th>1</th>\n",
" <td>PIK3CA</td>\n",
" <td>E545</td>\n",
" <td>single residue</td>\n",
" <td>K:575|G:21|Q:20|A:12|D:5</td>\n",
" <td>0.0</td>\n",
" <td>633</td>\n",
" <td>breast:174|bowel:97|bladder:90|lung:51|head_ne...</td>\n",
" <td>633</td>\n",
" <td>0</td>\n",
" <td>0</td>\n",
" <td>0</td>\n",
" <td>633</td>\n",
" <td>1.00000</td>\n",
" <td>0.00000</td>\n",
" <td>0.0</td>\n",
" <td>0.0</td>\n",
" </tr>\n",
" <tr>\n",
" <th>2</th>\n",
" <td>IDH1</td>\n",
" <td>R132</td>\n",
" <td>single residue</td>\n",
" <td>H:570|C:139|G:28|S:16|L:12|I:1</td>\n",
" <td>0.0</td>\n",
" <td>766</td>\n",
" <td>brain:612|biliary_tract:57|skin:25|blood:23|pr...</td>\n",
" <td>766</td>\n",
" <td>0</td>\n",
" <td>0</td>\n",
" <td>0</td>\n",
" <td>766</td>\n",
" <td>1.00000</td>\n",
" <td>0.00000</td>\n",
" <td>0.0</td>\n",
" <td>0.0</td>\n",
" </tr>\n",
" <tr>\n",
" <th>3</th>\n",
" <td>PIK3CA</td>\n",
" <td>H1047</td>\n",
" <td>single residue</td>\n",
" <td>R:537|L:85|Y:18|Q:7</td>\n",
" <td>0.0</td>\n",
" <td>647</td>\n",
" <td>breast:361|bowel:54|uterus:51|stomach:28|brain...</td>\n",
" <td>647</td>\n",
" <td>0</td>\n",
" <td>0</td>\n",
" <td>0</td>\n",
" <td>647</td>\n",
" <td>1.00000</td>\n",
" <td>0.00000</td>\n",
" <td>0.0</td>\n",
" <td>0.0</td>\n",
" </tr>\n",
" <tr>\n",
" <th>4</th>\n",
" <td>BRAF</td>\n",
" <td>V600</td>\n",
" <td>single residue</td>\n",
" <td>E:833|M:29|K:24|R:4|V:4|G:3</td>\n",
" <td>0.0</td>\n",
" <td>897</td>\n",
" <td>skin:357|thyroid:316|bowel:113|lung:33|unk:21|...</td>\n",
" <td>897</td>\n",
" <td>0</td>\n",
" <td>0</td>\n",
" <td>0</td>\n",
" <td>897</td>\n",
" <td>1.00000</td>\n",
" <td>0.00000</td>\n",
" <td>0.0</td>\n",
" <td>0.0</td>\n",
" </tr>\n",
" </tbody>\n",
"</table>\n",
"</div>"
],
"text/plain": [
" Gene Residue Type Variants Q-value \\\n",
"0 NRAS Q61 single residue R:204|K:142|L:46|H:27|P:2|*:1 0.0 \n",
"1 PIK3CA E545 single residue K:575|G:21|Q:20|A:12|D:5 0.0 \n",
"2 IDH1 R132 single residue H:570|C:139|G:28|S:16|L:12|I:1 0.0 \n",
"3 PIK3CA H1047 single residue R:537|L:85|Y:18|Q:7 0.0 \n",
"4 BRAF V600 single residue E:833|M:29|K:24|R:4|V:4|G:3 0.0 \n",
"\n",
" Samples Tumor Type Composition missense_count \\\n",
"0 422 skin:187|thyroid:71|blood:37|bowel:35|lung:17|... 421 \n",
"1 633 breast:174|bowel:97|bladder:90|lung:51|head_ne... 633 \n",
"2 766 brain:612|biliary_tract:57|skin:25|blood:23|pr... 766 \n",
"3 647 breast:361|bowel:54|uterus:51|stomach:28|brain... 647 \n",
"4 897 skin:357|thyroid:316|bowel:113|lung:33|unk:21|... 897 \n",
"\n",
" trunc_count inframe_count splice_count total_count missense_fraction \\\n",
"0 1 0 0 422 0.99763 \n",
"1 0 0 0 633 1.00000 \n",
"2 0 0 0 766 1.00000 \n",
"3 0 0 0 647 1.00000 \n",
"4 0 0 0 897 1.00000 \n",
"\n",
" trunc_fraction inframe_fraction splice_fraction \n",
"0 0.00237 0.0 0.0 \n",
"1 0.00000 0.0 0.0 \n",
"2 0.00000 0.0 0.0 \n",
"3 0.00000 0.0 0.0 \n",
"4 0.00000 0.0 0.0 "
]
},
"execution_count": 70,
"metadata": {},
"output_type": "execute_result"
}
],
"source": [
"h.head()"
]
},
{
"cell_type": "code",
"execution_count": 71,
"metadata": {
"collapsed": true
},
"outputs": [],
"source": [
"h.to_clipboard(index=False)"
]
},
{
"cell_type": "markdown",
"metadata": {},
"source": [
"results stored at [google docs](https://docs.google.com/spreadsheets/d/1vzcw3jgNsxgya8B7RZTn2Vw_9_Iuuqkj10aCs-S662M/edit#gid=0)"
]
}
],
"metadata": {
"kernelspec": {
"display_name": "Python [conda env:anaconda3]",
"language": "python",
"name": "conda-env-anaconda3-py"
},
"language_info": {
"codemirror_mode": {
"name": "ipython",
"version": 3
},
"file_extension": ".py",
"mimetype": "text/x-python",
"name": "python",
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Raw
hotspots_table_from_website.txt
Gene Residue Type Variants Q-value Samples Tumor Type Composition
NRAS Q61 single residue R:204|K:142|L:46|H:27|P:2|*:1 0 422 skin:187|thyroid:71|blood:37|bowel:35|lung:17|soft_tissue:11|unk:11|testis:9|bladder:8|brain:6|biliary_tract:5|ovary:5|uterus:5|head_neck:3|stomach:3|thymus:3|pancreas:2|adrenal_gland:1|bone:1|kidney:1|liver:1
PIK3CA E545 single residue K:575|G:21|Q:20|A:12|D:5 0 633 breast:174|bowel:97|bladder:90|lung:51|head_neck:48|stomach:35|cervix:34|uterus:30|brain:22|biliary_tract:8|kidney:8|prostate:8|skin:7|ovary:5|pancreas:5|penis:3|thyroid:3|testis:2|liver:1|unk:1|vulva:1
IDH1 R132 single residue H:570|C:139|G:28|S:16|L:12|I:1 0 766 brain:612|biliary_tract:57|skin:25|blood:23|prostate:11|lung:8|bone:6|bowel:5|liver:4|bladder:2|breast:2|head_neck:2|pancreas:2|soft_tissue:2|unk:2|adrenal_gland:1|thymus:1|thyroid:1
PIK3CA H1047 single residue R:537|L:85|Y:18|Q:7 0 647 breast:361|bowel:54|uterus:51|stomach:28|brain:27|head_neck:25|bladder:20|lung:17|soft_tissue:11|ovary:9|pancreas:7|prostate:6|kidney:5|skin:5|thyroid:5|unk:5|cervix:4|biliary_tract:3|liver:3|adrenal_gland:1
BRAF V600 single residue E:833|M:29|K:24|R:4|V:4|G:3 0 897 skin:357|thyroid:316|bowel:113|lung:33|unk:21|brain:20|blood:11|pancreas:10|biliary_tract:4|bladder:2|head_neck:2|ovary:2|breast:1|kidney:1|lymph:1|soft_tissue:1|stomach:1|uterus:1
EGFR L858 single residue R:144 0 144 lung:143|bowel:1
TP53 R175 single residue H:386|G:14|C:8|L:8 0 416 bowel:108|stomach:63|pancreas:39|brain:33|breast:29|lung:28|head_neck:24|ovary:21|prostate:14|uterus:14|soft_tissue:12|bladder:11|biliary_tract:5|unk:4|kidney:2|skin:2|thyroid:2|adrenal_gland:1|blood:1|cervix:1|liver:1|lymph:1
KRAS Q61 single residue H:108|R:37|L:21|K:20|P:2|A:1|E:1 0 190 pancreas:64|bowel:31|lung:28|blood:17|biliary_tract:8|thyroid:8|testis:6|bladder:5|stomach:5|prostate:4|uterus:4|skin:2|unk:2|ampulla_of_vater:1|brain:1|breast:1|liver:1|penis:1|soft_tissue:1
KRAS G13 single residue D:214|C:32|G:6|V:6|E:3|R:2|A:1 0 264 bowel:130|lung:57|stomach:17|blood:12|uterus:12|pancreas:7|unk:5|biliary_tract:4|cervix:4|bladder:3|lymph:3|skin:2|soft_tissue:2|ampulla_of_vater:1|brain:1|breast:1|liver:1|ovary:1|testis:1
TP53 R248 single residue Q:292|W:222|L:21|P:11|G:8|R:6 0 560 bowel:98|stomach:70|brain:54|lung:51|bladder:42|breast:34|uterus:33|ovary:32|pancreas:32|head_neck:28|skin:27|prostate:17|unk:10|soft_tissue:8|lymph:6|liver:5|blood:4|kidney:4|biliary_tract:2|ampulla_of_vater:1|bone:1|thymus:1
KRAS G12 single residue D:757|V:657|C:384|R:166|A:134|S:68|F:6|G:1|I:1|L:1 0 2175 pancreas:745|lung:570|bowel:500|uterus:84|unk:42|stomach:40|bladder:36|ovary:25|biliary_tract:21|testis:19|breast:15|cervix:15|blood:13|ampulla_of_vater:10|soft_tissue:8|brain:6|kidney:5|prostate:4|skin:4|head_neck:3|thyroid:3|lymph:2|thymus:2|bone:1|liver:1|vulva:1
TP53 R273 single residue C:283|H:251|L:56|S:12|P:5|G:2 0 609 brain:113|bowel:105|lung:78|stomach:74|breast:43|ovary:37|uterus:30|head_neck:29|pancreas:27|prostate:18|bladder:11|kidney:7|unk:6|blood:5|soft_tissue:5|biliary_tract:4|bone:3|liver:3|lymph:3|thyroid:3|skin:2|adrenal_gland:1|ampulla_of_vater:1|thymus:1
PIK3CA E542 single residue K:356|A:6|Q:5|V:3|G:2 0 372 breast:112|bladder:46|bowel:45|lung:32|head_neck:31|uterus:22|cervix:16|stomach:16|brain:10|kidney:8|unk:6|prostate:5|skin:4|biliary_tract:3|soft_tissue:3|ovary:2|pancreas:2|testis:2|thyroid:2|ampulla_of_vater:1|liver:1|lymph:1|thymus:1|vulva:1
AKT1 E17 single residue K:148|*:1 1.14602579830599e-288 149 breast:80|bowel:13|lung:8|prostate:8|uterus:8|bladder:6|unk:5|cervix:3|head_neck:3|stomach:3|thyroid:3|brain:2|ovary:2|biliary_tract:1|liver:1|lymph:1|pancreas:1|skin:1
GNAS R201 single residue H:69|C:65|S:3|L:2 7.46750176711196e-257 139 bowel:53|pancreas:35|stomach:17|lung:9|unk:5|liver:4|biliary_tract:3|cervix:3|ovary:2|adrenal_gland:1|ampulla_of_vater:1|bladder:1|bone:1|breast:1|head_neck:1|prostate:1|skin:1
FGFR3 S249 single residue C:114 3.49459925534527e-229 114 bladder:103|head_neck:5|lung:4|cervix:1|kidney:1
PIK3CA N345 single residue K:79|I:7|T:4|H:3|Y:3|D:1|N:1 3.86928187806421e-219 98 breast:51|uterus:11|bowel:9|lung:7|stomach:5|head_neck:4|brain:3|prostate:3|bladder:2|soft_tissue:2|testis:1
PTEN R130 single residue Q:72|G:44|*:38|P:6|L:5|R:2|S:1 1.91658796865309e-210 168 uterus:83|brain:14|breast:14|bowel:13|lung:8|prostate:8|skin:5|cervix:4|head_neck:4|stomach:3|biliary_tract:2|kidney:2|ovary:2|soft_tissue:2|penis:1|pleura:1|thyroid:1|unk:1
HRAS Q61 single residue R:56|K:28|L:16|H:2 8.14542563277525e-210 102 thyroid:22|bladder:19|adrenal_gland:17|head_neck:11|skin:11|prostate:10|lung:3|soft_tissue:3|brain:2|breast:1|stomach:1|thymus:1|vulva:1
TP53 Y220 single residue C:127|S:8|H:6|*:4|D:4|N:3 4.53756860311655e-208 152 brain:22|lung:20|ovary:20|breast:18|head_neck:12|pancreas:11|stomach:11|bowel:7|liver:7|soft_tissue:6|uterus:6|prostate:4|bladder:3|kidney:2|unk:2|skin:1
TP53 G245 single residue S:128|D:50|V:31|C:22|R:7|A:3|N:1 8.54722719468586e-208 242 bowel:49|lung:40|stomach:25|head_neck:19|brain:17|ovary:15|pancreas:15|prostate:14|breast:13|bladder:9|uterus:7|skin:4|kidney:3|liver:3|biliary_tract:2|soft_tissue:2|ampulla_of_vater:1|bone:1|cervix:1|lymph:1|thyroid:1
TP53 R213 single residue *:208|Q:25|L:17|G:4|P:2 1.2909718119355e-203 256 bowel:48|stomach:31|lung:22|breast:20|head_neck:19|skin:18|pancreas:17|bladder:12|brain:10|uterus:10|kidney:8|ovary:7|prostate:7|soft_tissue:7|liver:4|thyroid:3|unk:3|adrenal_gland:2|biliary_tract:2|lymph:2|ampulla_of_vater:1|cervix:1|penis:1|vulva:1
FBXW7 R465 single residue C:64|H:59|S:2|G:1|L:1|P:1 1.92461558472193e-192 128 bowel:53|uterus:25|stomach:15|bladder:7|lung:6|cervix:5|brain:4|head_neck:3|biliary_tract:2|breast:2|ovary:2|blood:1|lymph:1|pancreas:1|pleura:1
PIK3CA Q546 single residue K:35|R:31|P:19|H:5|E:2|L:1 1.38151348550833e-185 93 breast:22|bowel:21|uterus:15|brain:6|bladder:5|head_neck:5|prostate:4|stomach:4|soft_tissue:3|ovary:2|biliary_tract:1|cervix:1|lung:1|skin:1|thyroid:1|unk:1
ERBB2 S310 single residue F:95|Y:17|S:1 1.98484785043436e-185 113 bladder:56|breast:12|stomach:10|cervix:7|bowel:6|skin:6|lung:4|biliary_tract:3|head_neck:3|unk:3|ovary:2|soft_tissue:1
GNA11 Q209 single residue L:57|H:1|P:1 3.53820080128409e-183 59 eye:52|skin:6|bowel:1
GNAQ Q209 single residue P:42|L:22|H:1 4.59257795185295e-172 65 eye:57|skin:6|lung:1|testis:1
GTF2I L424 single residue H:68 3.8165837042307e-165 68 thymus:68
TP53 R282 single residue W:201|G:9|P:4|Q:3|L:1|R:1 5.73631626869356e-160 219 bowel:60|stomach:34|pancreas:22|brain:21|head_neck:18|lung:14|bladder:8|ovary:8|prostate:8|skin:8|breast:4|biliary_tract:2|kidney:2|lymph:2|soft_tissue:2|thymus:2|uterus:2|cervix:1|liver:1
CTNNB1 S37 single residue F:55|C:27|A:9|P:7|Y:5 2.59381163737272e-157 103 uterus:27|lung:25|liver:12|stomach:11|bladder:7|brain:5|prostate:4|pancreas:3|bowel:2|cervix:2|breast:1|head_neck:1|ovary:1|skin:1|unk:1
CTNNB1 D32 single residue Y:22|N:18|G:16|V:16|H:6|A:3 8.30436601169097e-155 81 liver:28|uterus:18|prostate:8|brain:6|lung:4|stomach:4|skin:3|bowel:2|cervix:2|pancreas:2|adrenal_gland:1|biliary_tract:1|bladder:1|ovary:1
SMAD4 R361 single residue H:60|C:54|S:4|G:3|L:2|P:1 1.13407719335173e-154 124 bowel:59|pancreas:22|stomach:17|biliary_tract:7|lung:5|breast:4|bladder:3|cervix:2|ampulla_of_vater:1|head_neck:1|prostate:1|skin:1|uterus:1
TP53 H179 single residue R:63|Y:41|L:14|Q:12|D:8|N:8|P:3 9.18618200580122e-150 149 lung:33|breast:17|brain:16|head_neck:13|pancreas:13|stomach:11|bowel:9|ovary:6|skin:6|uterus:6|prostate:4|bladder:3|liver:3|soft_tissue:3|unk:2|biliary_tract:1|blood:1|bone:1|thyroid:1
CTNNB1 S33 single residue C:32|F:29|P:16|Y:11|A:7|T:1 1.29715714396544e-144 96 uterus:24|liver:23|lung:11|brain:8|prostate:8|bladder:5|stomach:5|bowel:3|ovary:3|cervix:1|head_neck:1|pancreas:1|skin:1|thyroid:1|unk:1
KRAS A146 single residue T:65|V:16|P:5 5.76478689994657e-140 86 bowel:56|blood:6|stomach:6|lung:5|testis:5|unk:4|bladder:2|cervix:1|pancreas:1
CTNNB1 T41 single residue A:45|I:19|N:2 1.16454574986485e-135 66 liver:15|bowel:11|prostate:10|uterus:8|skin:6|lung:5|ampulla_of_vater:2|soft_tissue:2|unk:2|adrenal_gland:1|biliary_tract:1|bladder:1|ovary:1|pancreas:1
EGFR T790 single residue M:59|T:1 1.11200956013873e-133 60 lung:59|ovary:1
NRAS G12 single residue D:41|C:11|S:8|A:6|V:5|R:3 3.67050868081457e-130 74 bowel:30|blood:11|skin:11|testis:4|unk:4|uterus:4|head_neck:3|stomach:2|biliary_tract:1|bladder:1|brain:1|kidney:1|ovary:1
SF3B1 K700 single residue E:57|K:1|R:1 1.51874215150358e-126 59 breast:28|blood:15|pancreas:5|biliary_tract:2|kidney:2|lung:2|brain:1|lymph:1|prostate:1|soft_tissue:1|thymus:1
TP53 H193 single residue R:54|Y:31|L:19|P:8|D:5|N:5|Q:1 1.47914622326681e-124 123 breast:18|lung:18|brain:14|head_neck:10|ovary:9|stomach:9|pancreas:7|uterus:7|bladder:6|liver:6|prostate:4|bowel:3|kidney:3|soft_tissue:3|blood:2|bone:1|cervix:1|thymus:1|unk:1
ESR1 D538 single residue G:46 1.28855707547783e-123 46 breast:42|uterus:2|ovary:1|unk:1
FBXW7 R505 single residue C:41|G:31|H:4|L:4|P:2|S:1 5.90349136748716e-120 83 bowel:23|uterus:14|bladder:10|head_neck:9|stomach:7|lung:5|cervix:4|skin:3|unk:2|biliary_tract:1|blood:1|brain:1|ovary:1|pancreas:1|soft_tissue:1
IDH2 R172 single residue K:33|G:9|S:8|W:7|M:4|R:1|T:1 1.20402527166582e-117 63 brain:34|biliary_tract:9|lymph:8|blood:3|head_neck:2|liver:2|bladder:1|bone:1|bowel:1|kidney:1|unk:1
U2AF1 S34 single residue F:81|Y:4 4.3504059017074e-116 85 lung:41|bladder:9|pancreas:9|blood:8|uterus:7|biliary_tract:2|cervix:2|bowel:1|breast:1|head_neck:1|lymph:1|prostate:1|skin:1|unk:1
EGFR A289 single residue V:37|T:14|D:6|I:1|N:1 5.81115249692553e-116 59 brain:56|lung:2|head_neck:1
ESR1 Y537 single residue S:25|C:11|N:10|D:1 6.21076412839154e-115 47 breast:39|uterus:7|skin:1
CDKN2A R80 single residue *:97|Q:2 1.17629157106748e-111 99 head_neck:26|skin:17|pancreas:12|lung:11|stomach:11|bladder:5|bowel:5|unk:3|kidney:2|uterus:2|biliary_tract:1|brain:1|lymph:1|prostate:1|thymus:1
CTNNB1 S45 single residue F:31|P:29|C:5|Y:4|A:2 2.67102961964491e-111 71 liver:13|bowel:9|skin:8|adrenal_gland:6|bladder:6|prostate:6|lung:5|biliary_tract:4|pancreas:4|uterus:4|ampulla_of_vater:2|brain:1|soft_tissue:1|stomach:1|unk:1
TP53 C176 single residue F:54|Y:30|S:9|W:7|G:5|R:5|*:4|C:1 2.79789123298349e-94 115 bowel:19|lung:16|stomach:16|breast:13|ovary:12|head_neck:9|pancreas:7|prostate:5|brain:4|lymph:4|bone:2|kidney:2|biliary_tract:1|bladder:1|blood:1|liver:1|unk:1|uterus:1
PIK3CA R88 single residue Q:75 7.11268347015126e-94 75 uterus:23|bowel:20|brain:10|stomach:6|breast:5|bladder:3|head_neck:3|biliary_tract:1|lung:1|ovary:1|prostate:1|unk:1
ERBB3 V104 single residue M:40|L:21 2.90075860561392e-90 61 bowel:16|bladder:13|stomach:12|uterus:8|breast:4|cervix:4|biliary_tract:3|pancreas:1
PIK3CA M1043 single residue I:25|V:25|L:4|T:4 1.37438573866737e-88 58 uterus:13|brain:11|breast:11|bowel:7|head_neck:4|lung:4|thyroid:3|stomach:2|bladder:1|pancreas:1|soft_tissue:1
TP53 Y163 single residue C:54|H:11|N:9|D:3|*:2 6.75581008893545e-86 79 lung:21|ovary:11|head_neck:9|brain:7|breast:6|bowel:4|liver:4|stomach:4|prostate:3|pancreas:2|soft_tissue:2|uterus:2|ampulla_of_vater:1|bladder:1|lymph:1|skin:1
ERBB2 L755 single residue S:31|P:5|M:3|A:2|L:2|W:1 1.41038891943129e-85 44 breast:21|lung:6|bowel:4|bladder:3|stomach:3|uterus:3|ampulla_of_vater:1|biliary_tract:1|kidney:1|skin:1
TP53 R342 single residue *:129|P:8 1.47220591463954e-85 137 breast:26|bowel:24|stomach:16|lung:11|pancreas:10|skin:10|head_neck:8|brain:6|ovary:6|soft_tissue:4|uterus:4|bladder:3|biliary_tract:2|unk:2|ampulla_of_vater:1|bone:1|liver:1|prostate:1|thymus:1
TP53 R196 single residue *:131|P:8|L:1|Q:1 4.00457696564295e-85 141 bowel:25|stomach:21|breast:17|head_neck:17|brain:13|pancreas:13|lung:10|skin:8|ovary:6|kidney:2|prostate:2|unk:2|biliary_tract:1|bladder:1|blood:1|lymph:1|uterus:1
H3F3A K28 single residue M:32|R:1 5.3294455724506e-83 33 brain:32|pancreas:1
FGFR3 Y373 single residue C:32 7.46580235069588e-83 32 bladder:31|kidney:1
BRAF G469 single residue A:34|V:11|R:8|E:4|S:2|*:1|G:1 3.65455186277771e-82 61 lung:23|skin:13|bowel:6|blood:3|bladder:2|brain:2|lymph:2|prostate:2|unk:2|adrenal_gland:1|biliary_tract:1|head_neck:1|stomach:1|thyroid:1|uterus:1
PIK3CA C420 single residue R:46 2.5982410627491e-80 46 breast:15|bowel:7|lung:5|head_neck:4|uterus:4|brain:3|prostate:2|stomach:2|biliary_tract:1|ovary:1|soft_tissue:1|unk:1
HRAS G13 single residue R:22|V:15|D:6|C:3|S:2|I:1|N:1 5.5041445937963e-80 50 head_neck:16|bladder:11|skin:7|lung:6|thymus:3|adrenal_gland:2|breast:2|bowel:1|soft_tissue:1|unk:1
CTNNB1 G34 single residue R:28|V:14|E:8|*:1|A:1|L:1 2.2102778557963e-79 53 uterus:15|liver:9|lung:8|brain:4|skin:4|adrenal_gland:3|prostate:2|stomach:2|unk:2|bladder:1|bowel:1|head_neck:1|pancreas:1
TP53 I195 single residue T:42|F:19|N:10|S:4|M:2|I:1|K:1 5.3117975300635e-77 79 breast:16|ovary:13|lung:9|pancreas:7|stomach:7|brain:6|blood:4|bowel:4|head_neck:4|liver:3|uterus:2|ampulla_of_vater:1|bladder:1|pleura:1|soft_tissue:1
CDKN2A H83 single residue Y:48|D:6|R:4|N:2|Q:2 1.3094103357572e-75 62 lung:12|pancreas:12|skin:7|stomach:6|bladder:4|head_neck:4|biliary_tract:3|brain:3|breast:3|bowel:2|ovary:2|soft_tissue:2|liver:1|vulva:1
TP53 X187 single residue sp:100 1.82472984264798e-75 100 lung:20|breast:14|ovary:11|stomach:11|bowel:7|head_neck:7|skin:7|pancreas:6|soft_tissue:5|brain:4|bladder:2|uterus:2|blood:1|kidney:1|liver:1|prostate:1
TP53 G266 single residue R:40|E:35|V:26|*:14|K:1|T:1 1.57992511675724e-74 117 lung:21|bowel:12|pancreas:11|brain:9|breast:9|head_neck:8|ovary:7|skin:7|stomach:6|uterus:5|bladder:4|prostate:3|soft_tissue:3|biliary_tract:2|blood:2|liver:2|ampulla_of_vater:1|kidney:1|lymph:1|pleura:1|unk:1|vulva:1
TP53 R249 single residue S:45|M:17|G:15|T:11|W:11|K:2|I:1 1.28532741635959e-72 102 lung:33|liver:13|breast:7|brain:6|head_neck:6|stomach:6|pancreas:5|prostate:4|uterus:4|bladder:3|bowel:3|skin:3|unk:3|thyroid:2|adrenal_gland:1|lymph:1|ovary:1|soft_tissue:1
SF3B1 R625 single residue H:29|C:25|L:4|G:1 1.5407254801883e-72 59 eye:27|bowel:10|skin:7|head_neck:3|vulva:3|bladder:2|blood:2|breast:1|kidney:1|lymph:1|pancreas:1|soft_tissue:1
BRAF K601 single residue E:32|N:5|T:1 1.94975462848428e-70 38 skin:8|lung:6|prostate:6|lymph:4|bowel:2|stomach:2|thyroid:2|unk:2|uterus:2|biliary_tract:1|blood:1|breast:1|head_neck:1
BRAF D594 single residue N:24|G:21|V:2|Y:2|E:1|H:1 9.78698184667661e-70 51 bowel:12|lung:10|bladder:6|skin:6|blood:3|unk:3|lymph:2|stomach:2|adrenal_gland:1|biliary_tract:1|brain:1|cervix:1|head_neck:1|prostate:1|testis:1
EZH2 Y646 single residue F:13|N:13|H:6|S:4|C:1|Y:1 6.87377238358676e-69 38 lymph:23|skin:10|bone:3|biliary_tract:1|unk:1
TP53 Y234 single residue C:42|H:9|*:6|N:6|S:3|D:2 4.21073846121301e-68 68 lung:11|brain:7|breast:6|ovary:6|pancreas:5|stomach:5|bladder:3|bowel:3|head_neck:3|prostate:3|soft_tissue:3|biliary_tract:2|liver:2|skin:2|unk:2|adrenal_gland:1|ampulla_of_vater:1|bone:1|kidney:1|vulva:1
DNMT3A R882 single residue H:28|C:10|P:1 1.73894288218144e-67 39 blood:30|lymph:4|bowel:1|brain:1|breast:1|lung:1|pleura:1
BCOR N1459 single residue S:36 2.0435075018722e-67 36 uterus:23|lung:8|ovary:2|unk:2|bowel:1
PPP2R1A P179 single residue R:29|L:1 3.79894395598156e-66 30 uterus:27|ovary:1|soft_tissue:1|unk:1
RAC1 P29 single residue S:43|L:7|T:2|F:1 1.55867535683403e-65 53 skin:42|unk:4|head_neck:3|breast:1|soft_tissue:1|thyroid:1|uterus:1
PIK3CA G118 single residue D:40 1.608288709768e-65 40 breast:9|brain:8|uterus:8|bowel:2|head_neck:2|lung:2|stomach:2|ampulla_of_vater:1|bladder:1|cervix:1|kidney:1|pancreas:1|prostate:1|thyroid:1
FBXW7 R479 single residue Q:31|*:8|G:8|P:7|L:2|R:1 4.37689458184735e-63 57 bowel:12|uterus:12|bladder:8|head_neck:5|cervix:4|lung:4|stomach:4|breast:2|brain:1|eye:1|kidney:1|lymph:1|penis:1|skin:1
TP53 X307 single residue sp:77 1.53643954111284e-62 77 lung:16|bowel:9|head_neck:9|breast:7|ovary:6|stomach:6|brain:4|liver:4|bladder:3|unk:3|pancreas:2|prostate:2|soft_tissue:2|adrenal_gland:1|biliary_tract:1|kidney:1|skin:1
TP53 V173 single residue L:42|M:27|A:4|G:4|E:1 7.25981161558513e-62 78 bowel:12|stomach:10|lung:9|head_neck:7|brain:6|breast:6|pancreas:4|bladder:3|bone:3|lymph:3|ovary:3|uterus:3|prostate:2|unk:2|adrenal_gland:1|ampulla_of_vater:1|liver:1|pleura:1|skin:1
TP53 C238 single residue Y:40|F:23|R:5|G:4|S:4|W:1 7.74651843586856e-62 77 lung:11|brain:8|pancreas:8|bladder:6|uterus:6|bowel:5|breast:5|head_neck:5|ovary:5|stomach:5|prostate:3|soft_tissue:3|blood:2|skin:2|cervix:1|liver:1|lymph:1
PPP2R1A R183 single residue W:33|Q:17|G:1 9.6264551563176e-61 51 bowel:12|uterus:11|ovary:6|breast:4|head_neck:3|lung:3|prostate:3|stomach:2|biliary_tract:1|bladder:1|eye:1|pancreas:1|soft_tissue:1|thyroid:1|unk:1
MYD88 L265 single residue P:37 1.26353661666745e-60 37 lymph:19|blood:13|lung:2|bladder:1|bowel:1|peritoneum:1
TP53 X126 single residue sp:75 5.81977745695617e-59 75 lung:14|breast:11|stomach:8|ovary:7|bowel:5|pancreas:5|brain:4|uterus:4|prostate:3|blood:2|liver:2|skin:2|unk:2|biliary_tract:1|bladder:1|bone:1|head_neck:1|kidney:1|soft_tissue:1
NRAS G13 single residue R:18|D:16|S:3|C:2|F:1|V:1 3.59718742726763e-58 41 blood:13|bowel:10|skin:7|biliary_tract:2|brain:2|bladder:1|lung:1|lymph:1|soft_tissue:1|stomach:1|testis:1|unk:1
TP53 Y205 single residue C:35|H:8|F:6|S:6|D:3|N:2|*:1 7.4725061476356e-58 61 lung:9|bowel:7|breast:7|stomach:7|pancreas:6|brain:4|liver:4|lymph:3|head_neck:2|ovary:2|unk:2|uterus:2|biliary_tract:1|bladder:1|blood:1|kidney:1|skin:1|soft_tissue:1
PIK3CA E726 single residue K:53|A:2 1.11290833591147e-57 55 breast:24|bladder:6|lung:6|bowel:5|cervix:3|head_neck:2|prostate:2|stomach:2|bone:1|brain:1|pancreas:1|skin:1|uterus:1
TP53 P151 single residue S:36|H:13|A:11|R:9|T:8|F:1|L:1 1.30026283538923e-57 79 bowel:12|head_neck:8|lung:7|breast:6|pancreas:6|ovary:5|skin:5|stomach:5|bladder:4|brain:4|unk:4|uterus:3|kidney:2|liver:2|prostate:2|soft_tissue:2|blood:1|thyroid:1
CDKN2A R58 single residue *:61|R:1 2.55970323759759e-57 62 skin:16|head_neck:14|pancreas:8|stomach:7|lung:5|bladder:2|lymph:2|soft_tissue:2|unk:2|ampulla_of_vater:1|kidney:1|ovary:1|penis:1
EGFR G598 single residue V:27|A:5|E:1 6.32187956175441e-57 33 brain:31|lung:1|stomach:1
TP53 R158 single residue L:42|H:36|P:11|G:9|C:5|S:2|F:1 8.56420853444971e-57 106 lung:55|brain:14|bowel:7|stomach:5|bladder:4|prostate:4|uterus:4|head_neck:2|liver:2|unk:2|ampulla_of_vater:1|biliary_tract:1|breast:1|kidney:1|ovary:1|skin:1|soft_tissue:1
TP53 Y236 single residue C:40|*:5|D:5|N:5|H:2|S:2 1.29867077765943e-56 59 lung:11|bowel:8|breast:7|head_neck:7|brain:6|pancreas:4|prostate:3|skin:3|bladder:2|lymph:2|ovary:2|ampulla_of_vater:1|soft_tissue:1|stomach:1|thyroid:1
B2M M1 single residue I:11|L:11|V:9|T:4|K:3|R:3 3.76576315904147e-56 41 lymph:11|lung:10|head_neck:3|ovary:3|skin:3|stomach:3|uterus:3|bowel:2|bladder:1|blood:1|pancreas:1
HRAS G12 single residue D:14|S:14|C:4|V:3|A:2|N:1 4.29398355982767e-56 38 head_neck:18|bladder:10|skin:5|soft_tissue:2|breast:1|cervix:1|unk:1
FGFR3 R248 single residue C:31 2.24097601387903e-52 31 bladder:25|head_neck:2|lung:2|blood:1|breast:1
TP53 C275 single residue F:25|Y:24|R:7|S:6|*:3|W:3|G:2 9.26247541784713e-52 70 lung:15|brain:8|bowel:6|stomach:6|ovary:5|head_neck:4|prostate:4|breast:3|liver:3|skin:3|soft_tissue:3|bladder:2|blood:2|adrenal_gland:1|biliary_tract:1|kidney:1|pancreas:1|thyroid:1|uterus:1
TP53 C135 single residue Y:27|F:24|R:9|*:4|S:4|W:4|G:2 3.52776955427228e-50 74 stomach:17|lung:10|bowel:9|breast:9|kidney:5|prostate:5|pancreas:4|bladder:3|ovary:3|brain:2|soft_tissue:2|unk:2|liver:1|lymph:1|thyroid:1
TP53 P278 single residue S:37|L:17|A:13|R:12|T:12|H:6|F:3 5.74722717996462e-50 100 lung:18|skin:12|bowel:10|head_neck:9|stomach:9|ovary:8|bladder:7|breast:7|brain:5|pancreas:5|prostate:4|uterus:2|blood:1|kidney:1|soft_tissue:1|unk:1
IDH2 R140 single residue Q:20|W:2|L:1 1.57907449279138e-48 23 blood:19|bowel:1|head_neck:1|pancreas:1|stomach:1
SPOP F133 single residue L:32|V:19|C:8|S:5|I:3 9.29184493038497e-48 67 prostate:67
PIK3CA K111 single residue E:22|N:14|Q:1|R:1 3.93686007081858e-47 38 breast:8|uterus:8|bowel:6|stomach:5|brain:4|head_neck:2|lung:2|biliary_tract:1|blood:1|cervix:1
TP53 S241 single residue F:51|C:19|Y:15|P:6|S:3|A:2|T:1 7.17889662377449e-46 97 lung:16|bladder:10|bowel:9|ovary:8|skin:8|breast:7|uterus:6|brain:5|pancreas:5|stomach:5|kidney:4|biliary_tract:3|soft_tissue:3|head_neck:2|prostate:2|cervix:1|lymph:1|thyroid:1|unk:1
EGFR G719 single residue A:18|C:7|S:5|D:3 1.15873816487001e-45 33 lung:27|brain:3|bladder:1|breast:1|stomach:1
TP53 M237 single residue I:55|K:5|V:4 8.54847258220565e-45 64 lung:12|stomach:11|brain:9|bowel:8|ovary:5|head_neck:4|breast:3|pancreas:3|uterus:3|soft_tissue:2|bladder:1|eye:1|prostate:1|unk:1
FGFR2 N549 single residue K:21|H:3|S:1|T:1 2.63567113536069e-44 26 breast:9|bladder:6|uterus:6|lung:2|stomach:2|head_neck:1
RXRA S427 single residue F:22|Y:4 4.52406657388826e-44 26 bladder:23|liver:1|pancreas:1|soft_tissue:1
NFE2L2 R34 single residue G:16|Q:11|P:5|*:1|L:1 9.73572135889331e-44 34 lung:12|bladder:8|head_neck:7|uterus:2|cervix:1|kidney:1|pancreas:1|stomach:1|thyroid:1
TP53 V157 single residue F:67|G:4|L:3|A:1|D:1|V:1 1.04043861763858e-43 77 lung:36|ovary:9|head_neck:6|breast:5|brain:4|pancreas:4|bladder:3|bowel:3|liver:3|prostate:2|biliary_tract:1|stomach:1
MAP2K1 K57 single residue N:16|T:7|E:6 1.73493302101363e-43 29 lung:7|bowel:5|lymph:4|biliary_tract:2|prostate:2|skin:2|stomach:2|unk:2|brain:1|breast:1|head_neck:1
AR L702 single residue H:18|L:1 2.56839664672137e-43 19 prostate:18|bowel:1
TP53 V272 single residue M:34|L:20|G:5|E:3|K:2|A:1|V:1 9.58986476133168e-43 66 lung:12|pancreas:8|breast:7|ovary:7|bowel:6|stomach:5|brain:4|head_neck:4|bladder:2|kidney:2|prostate:2|skin:2|biliary_tract:1|blood:1|soft_tissue:1|unk:1|uterus:1
FLT3 D835 single residue Y:11|E:3|H:2|V:1 1.02500063276241e-41 17 blood:17
ATM R337 single residue C:31|H:9 3.53306905480388e-41 40 bowel:17|skin:4|lung:3|bladder:2|breast:2|head_neck:2|pancreas:2|stomach:2|uterus:2|penis:1|prostate:1|soft_tissue:1|unk:1
TP53 K132 single residue N:30|R:27|E:14|M:5|T:4|Q:2|*:1 1.67435535883697e-40 83 lung:17|brain:9|bladder:8|breast:8|bowel:7|ovary:7|pancreas:7|prostate:3|soft_tissue:3|stomach:3|skin:2|uterus:2|adrenal_gland:1|blood:1|cervix:1|head_neck:1|kidney:1|pleura:1|unk:1
CIC R215 single residue W:17|Q:7|R:1 5.57740350592312e-40 25 brain:22|bowel:1|lung:1|skin:1
PIK3CA E453 single residue K:31|Q:10|D:1 3.19949611689526e-39 42 breast:16|bladder:8|brain:6|lung:3|stomach:2|uterus:2|bowel:1|cervix:1|head_neck:1|liver:1|unk:1
CDKN2A W110 single residue *:45 5.2042461618899e-39 45 head_neck:15|skin:11|lung:5|brain:4|pancreas:3|stomach:3|uterus:2|bladder:1|soft_tissue:1
TP53 R280 single residue K:36|T:34|G:17|I:12|S:8|*:2 8.52038865841413e-39 109 bladder:33|lung:20|breast:10|head_neck:9|brain:5|skin:5|stomach:4|ovary:3|pancreas:3|uterus:3|bowel:2|liver:2|soft_tissue:2|thyroid:2|unk:2|biliary_tract:1|blood:1|cervix:1|prostate:1
GTF2I N440 single residue S:19 7.49957559915763e-38 19 stomach:9|soft_tissue:4|bladder:2|biliary_tract:1|lymph:1|prostate:1|testis:1
NFE2L2 E79 single residue Q:17|K:11|*:2|V:2|D:1|G:1 7.468598929185e-37 34 lung:11|head_neck:10|bladder:4|stomach:4|cervix:2|liver:2|brain:1
ERBB2 R678 single residue Q:31|W:1 9.16633419802267e-37 32 bowel:9|stomach:9|bladder:6|uterus:4|breast:2|prostate:1|unk:1
TP53 S215 single residue I:20|R:13|G:8|N:7|C:1|T:1 1.43787287066506e-36 50 lung:14|bowel:6|pancreas:5|prostate:4|stomach:4|liver:3|brain:2|breast:2|ovary:2|uterus:2|bladder:1|blood:1|head_neck:1|kidney:1|soft_tissue:1|thyroid:1
MET X1010 single residue sp:19 3.32303024415133e-36 19 lung:18|brain:1
BRAF N581 single residue S:13|I:3|T:2|D:1|H:1|Y:1 3.87360672866837e-36 21 bowel:5|lung:5|skin:5|ovary:2|blood:1|kidney:1|stomach:1|unk:1
KIT N822 single residue K:14|Y:6|I:1 2.30956061262686e-35 21 testis:10|soft_tissue:5|skin:3|bowel:2|unk:1
RHOA G17 single residue V:16|E:15|A:5 4.09456295032167e-35 36 lymph:14|breast:10|bladder:4|bowel:2|stomach:2|unk:2|ovary:1|skin:1
CDK4 R24 single residue L:10|H:7|C:4|S:2 5.35320558359261e-35 23 skin:11|lung:10|bladder:1|blood:1
BRAF G466 single residue V:17|E:14|A:3 6.72195069896094e-35 34 lung:17|blood:4|skin:4|bowel:3|unk:2|bladder:1|brain:1|head_neck:1|prostate:1
AR T878 single residue A:14|S:1 8.20730580930317e-35 15 prostate:15
PTEN R233 single residue *:45|Q:1 1.42029736852695e-34 46 uterus:16|brain:8|bowel:7|stomach:3|breast:2|lymph:2|prostate:2|bladder:1|cervix:1|kidney:1|lung:1|ovary:1|thyroid:1
TP53 N239 single residue S:19|D:18|K:2|H:1|T:1 3.83729752034833e-34 41 lung:7|uterus:7|breast:6|head_neck:3|kidney:3|prostate:3|bowel:2|lymph:2|pancreas:2|adrenal_gland:1|bladder:1|brain:1|liver:1|ovary:1|stomach:1
AR H875 single residue Y:16 7.63404370123561e-34 16 prostate:16
POLE P286 single residue R:23|H:1|L:1|S:1|T:1 1.11888229227845e-33 27 uterus:11|bowel:9|bladder:2|breast:2|pancreas:1|prostate:1|stomach:1
CREBBP R1446 single residue C:14|H:10|L:6|G:1|P:1|S:1 1.12282141286262e-33 33 lymph:5|bladder:4|bowel:4|head_neck:4|brain:3|lung:3|stomach:3|cervix:2|liver:2|skin:2|pleura:1
TP53 C242 single residue F:27|Y:12|S:9|W:4|G:3|R:2|*:1|C:1 1.17967885828529e-33 59 lung:17|bowel:6|head_neck:6|breast:5|stomach:5|uterus:4|liver:3|pancreas:3|bladder:2|blood:2|brain:2|kidney:1|prostate:1|soft_tissue:1|unk:1
CD79B Y197 single residue H:5|C:2|D:2|F:2|N:2|S:2|R:1 1.2515091895722e-33 16 lymph:16
NFE2L2 E82 single residue D:13|A:3|G:3|Q:2 4.89627732972955e-33 21 uterus:7|liver:4|kidney:2|lung:2|stomach:2|biliary_tract:1|bladder:1|bowel:1|cervix:1
PIK3CA V344 single residue G:13|M:11|A:2 5.84970496650592e-33 26 bowel:6|uterus:6|brain:3|breast:2|skin:2|cervix:1|head_neck:1|lymph:1|prostate:1|soft_tissue:1|stomach:1|unk:1
TP53 X261 single residue sp:51 6.79062733955428e-33 51 lung:13|breast:7|stomach:6|ovary:5|bowel:4|head_neck:4|bladder:2|brain:2|kidney:1|liver:1|lymph:1|pancreas:1|prostate:1|soft_tissue:1|unk:1|uterus:1
MED12 G44 single residue S:8|D:6|C:5|A:4|V:2 1.20697083885738e-32 25 uterus:8|bowel:4|biliary_tract:2|bladder:2|brain:2|breast:2|soft_tissue:2|blood:1|lymph:1|prostate:1
EGFR L861 single residue Q:21 7.90212878554118e-32 21 lung:19|bowel:2
ERBB4 S1289 single residue A:12 8.08817732031978e-32 12 bladder:12
TP53 G244 single residue D:21|C:19|S:15|V:6|A:1|F:1|G:1|R:1 1.00026964688445e-31 65 lung:17|brain:8|ovary:7|stomach:7|bowel:5|bladder:3|lymph:3|uterus:3|breast:2|head_neck:2|soft_tissue:2|biliary_tract:1|cervix:1|kidney:1|liver:1|pancreas:1|unk:1
PIK3CA R93 single residue Q:18|W:12|L:1 1.87724928790338e-31 31 uterus:11|stomach:5|bowel:4|bladder:3|breast:3|brain:2|cervix:2|lung:1
MED12 L1224 single residue F:16|V:2 1.98093425904712e-31 18 prostate:14|breast:1|lung:1|pancreas:1|stomach:1
ERCC2 N238 single residue S:16 2.0595128011563e-31 16 bladder:14|breast:1|kidney:1
FOXL2 C134 single residue W:12 4.37607216698428e-31 12 ovary:12
STK19 D89 single residue N:16|D:2 7.07803453190923e-31 18 skin:18
TP53 V274 single residue F:14|A:12|G:8|D:7|L:5 9.09067281233547e-31 46 lung:11|breast:8|bowel:4|pancreas:4|stomach:4|brain:3|liver:3|prostate:3|bladder:2|ovary:2|skin:1|uterus:1
PIK3CA R108 single residue H:25|L:3|S:1 2.1807379100544e-30 29 bowel:8|uterus:6|lung:3|biliary_tract:2|lymph:2|bladder:1|bone:1|brain:1|breast:1|ovary:1|prostate:1|skin:1|stomach:1
MAPK1 E322 single residue K:24|*:1|A:1 2.78211627645888e-30 26 head_neck:12|cervix:7|bladder:4|lung:1|lymph:1|skin:1
XPO1 E571 single residue K:25|A:1|V:1 3.18647292377788e-30 27 blood:7|lymph:7|breast:4|bowel:3|uterus:3|prostate:2|bladder:1
RHOA Y42 single residue C:14|S:3|F:1|I:1 8.6265832611386e-30 19 stomach:16|ampulla_of_vater:1|head_neck:1|lymph:1
NFE2L2 D29 single residue H:19|Y:7|G:2|N:2 1.19589215959561e-29 30 lung:10|head_neck:6|bladder:5|cervix:3|kidney:3|bowel:1|stomach:1|uterus:1
ERBB2 V777 single residue L:17|M:3 2.19804285674572e-29 20 breast:6|bowel:5|stomach:5|bladder:2|ampulla_of_vater:1|head_neck:1
TP53 X331 single residue sp:49 4.86590998582027e-29 49 bowel:9|breast:9|lung:8|ovary:7|bladder:3|pancreas:3|head_neck:2|biliary_tract:1|blood:1|liver:1|lymph:1|prostate:1|skin:1|soft_tissue:1|unk:1
KIT D816 single residue V:11|H:5|Y:5|A:1 1.55789397481015e-28 22 testis:13|blood:5|unk:4
KRAS G60 single residue G:19|D:2|V:2|S:1 2.36547550250116e-28 24 bowel:9|bladder:2|pancreas:2|skin:2|stomach:2|thyroid:2|unk:2|biliary_tract:1|blood:1|lung:1
ALK R1275 single residue Q:16|*:1|L:1 6.65371720051819e-28 18 brain:15|bowel:1|breast:1|prostate:1
CTNNB1 K335 single residue I:16|T:3 1.26036406875161e-27 19 liver:11|bowel:3|biliary_tract:1|penis:1|prostate:1|skin:1|stomach:1
ALK F1174 single residue L:11|C:2|V:1 1.9674160903607e-27 14 brain:12|kidney:1|lung:1
ERBB2 V842 single residue I:26 2.90199531502456e-27 26 bowel:8|uterus:7|pancreas:3|stomach:3|bladder:2|biliary_tract:1|breast:1|prostate:1
MAP2K1 P124 single residue S:15|L:6|M:1|P:1|Q:1|R:1 5.99241948540617e-27 25 skin:20|unk:2|bladder:1|bowel:1|uterus:1
SMAD4 D537 single residue G:10|H:6|V:5|E:4|Y:4|A:1 6.16661226103394e-27 30 bowel:19|pancreas:5|lung:3|stomach:2|ovary:1
TP53 E285 single residue K:68|*:15|V:9|E:4|Q:3 1.42429549670277e-26 99 bladder:33|lung:15|breast:10|stomach:8|skin:6|bowel:5|head_neck:5|unk:4|biliary_tract:3|cervix:2|prostate:2|adrenal_gland:1|bone:1|lymph:1|pleura:1|thyroid:1|uterus:1
TP53 R306 single residue *:85|Q:1 1.86197213934107e-26 86 stomach:20|bowel:17|breast:10|head_neck:7|brain:6|pancreas:6|ovary:5|liver:3|lung:3|biliary_tract:2|bladder:2|unk:2|kidney:1|soft_tissue:1|uterus:1
TP53 H214 single residue R:35|L:2|Q:2|P:1 3.13070819109956e-26 40 lung:10|pancreas:6|stomach:4|bladder:3|brain:3|bowel:2|liver:2|ovary:2|soft_tissue:2|thyroid:2|blood:1|kidney:1|lymph:1|uterus:1
SMARCA4 T910 single residue M:26|A:1|R:1|T:1 3.37629225284153e-26 29 stomach:6|brain:5|pancreas:3|bone:2|bowel:2|lung:2|uterus:2|bladder:1|breast:1|eye:1|kidney:1|prostate:1|thymus:1|unk:1
PIK3CA G106 single residue V:14|R:6|C:1|S:1 6.87260103192609e-26 22 bladder:4|uterus:4|brain:3|bowel:2|breast:2|lung:2|prostate:2|cervix:1|kidney:1|skin:1
HIST1H3B K28 single residue M:11|E:1 1.52283836674349e-25 12 brain:11|head_neck:1
POLE V411 single residue L:18 2.55791309710685e-25 18 uterus:10|bowel:4|brain:1|penis:1|stomach:1|unk:1
CDH1 Q23 single residue *:19 5.17732153717184e-25 19 breast:16|stomach:2|bladder:1
FGFR1 N577 single residue K:17|D:2 5.27840065160741e-25 19 brain:11|soft_tissue:3|adrenal_gland:2|breast:1|cervix:1|stomach:1
TP53 E286 single residue K:41|*:14|Q:7|G:6|V:3|A:2 7.08380811769577e-25 73 lung:12|skin:10|breast:9|bladder:6|stomach:6|bowel:5|head_neck:4|pancreas:4|soft_tissue:4|brain:3|liver:2|lymph:2|biliary_tract:1|blood:1|ovary:1|prostate:1|unk:1|uterus:1
RAF1 S257 single residue L:24|W:1 3.23332678171542e-24 25 bowel:11|lung:5|skin:3|stomach:3|bladder:1|unk:1|vulva:1
FGFR2 S252 single residue W:18|L:2|S:2 4.17409859833416e-24 22 uterus:16|stomach:2|bladder:1|breast:1|ovary:1|unk:1
KRAS K117 single residue N:17|R:1 5.40950832194339e-24 18 bowel:9|blood:3|stomach:2|liver:1|skin:1|soft_tissue:1|unk:1
EGFR R108 single residue K:17|G:2 5.53217157202984e-24 19 brain:18|stomach:1
PIK3R1 N564 single residue D:17 1.08334499567202e-23 17 brain:6|bowel:5|uterus:2|lung:1|skin:1|soft_tissue:1|stomach:1
NFE2L2 G31 single residue A:9|E:7|R:4|V:1 2.43250010760161e-23 21 lung:8|stomach:4|bladder:2|breast:2|head_neck:2|bowel:1|liver:1|uterus:1
NFE2L2 G81 single residue S:6|V:4|D:3|R:3|C:2|A:1 2.60359287698573e-23 19 lung:5|kidney:4|stomach:3|liver:2|uterus:2|bladder:1|breast:1|head_neck:1
TCEB1 Y79 single residue C:6|*:1|F:1|N:1|S:1 2.66761546087334e-23 10 kidney:10
MAP2K1 F53 single residue L:12|C:2|V:2|I:1 7.28455410553735e-23 17 bladder:3|bowel:3|stomach:3|lung:2|blood:1|kidney:1|lymph:1|skin:1|soft_tissue:1|thymus:1
ERBB3 E928 single residue G:15|K:2 8.04884338962201e-23 17 breast:8|bladder:2|bowel:2|biliary_tract:1|kidney:1|lung:1|stomach:1|uterus:1
ERBB3 D297 single residue Y:18|A:1|H:1|N:1|V:1 8.04884338962201e-23 22 bladder:6|stomach:5|uterus:4|breast:3|bowel:2|biliary_tract:1|lung:1
TP53 X225 single residue sp:46 9.76065282760022e-23 46 lung:10|breast:7|head_neck:5|brain:3|kidney:3|ovary:3|skin:3|stomach:3|uterus:3|bowel:2|blood:1|liver:1|prostate:1|unk:1
TP53 C141 single residue Y:25|W:9|R:5|G:4|*:2|F:1|S:1 1.81124424263192e-22 47 breast:9|bowel:5|lung:4|pancreas:4|prostate:4|brain:3|uterus:3|biliary_tract:2|bladder:2|blood:2|head_neck:2|ovary:2|stomach:2|kidney:1|liver:1|soft_tissue:1
TP53 D281 single residue E:14|N:14|Y:13|H:9|V:9|D:4|G:4|A:1|P:1 3.56196704807636e-22 69 lung:16|brain:10|breast:7|bladder:6|skin:5|uterus:5|ovary:4|pancreas:3|blood:2|kidney:2|soft_tissue:2|biliary_tract:1|bone:1|bowel:1|head_neck:1|liver:1|stomach:1|unk:1
EP300 D1399 single residue N:20|Y:2|E:1 6.88350174669892e-22 23 head_neck:6|cervix:5|lung:3|stomach:3|bladder:2|bowel:1|brain:1|lymph:1|uterus:1
TP53 V216 single residue M:24|L:9|G:5|E:4 7.05793465485541e-22 42 lung:7|breast:6|brain:5|ovary:4|pancreas:3|prostate:3|head_neck:2|lymph:2|skin:2|stomach:2|uterus:2|biliary_tract:1|bowel:1|liver:1|soft_tissue:1
NUP93 Q15 single residue *:15|K:1 7.3825565595655e-22 16 bladder:5|thyroid:4|breast:2|lung:2|cervix:1|ovary:1|uterus:1
SMAD4 G386 single residue D:9|V:6|S:3|R:2|A:1|C:1 8.21942263343406e-22 22 stomach:8|bowel:6|pancreas:5|breast:1|lung:1|prostate:1
TP53 X125 single residue sp:43 8.50379958533421e-22 43 lung:7|stomach:7|brain:4|breast:4|head_neck:4|skin:4|ovary:2|pancreas:2|soft_tissue:2|adrenal_gland:1|biliary_tract:1|bone:1|bowel:1|unk:1|uterus:1|vulva:1
TP53 R337 single residue C:36|L:20|H:4|S:4|P:3|G:1 8.69771954614254e-22 68 lung:17|bowel:11|breast:6|head_neck:5|adrenal_gland:3|pancreas:3|stomach:3|unk:3|brain:2|kidney:2|liver:2|prostate:2|uterus:2|biliary_tract:1|bladder:1|blood:1|cervix:1|ovary:1|skin:1|soft_tissue:1
EGFR S768 single residue I:14|T:1 1.19234002187539e-21 15 lung:14|bowel:1
EIF1AX X113 single residue sp:11 1.63796513654497e-21 11 thyroid:11
PTPN11 A72 single residue T:6|V:6|D:3|G:2|S:1 3.59179236148491e-21 18 brain:14|blood:3|breast:1
MYCN P44 single residue L:19|F:1 7.3609248682335e-21 20 brain:8|skin:4|uterus:4|pancreas:3|head_neck:1
SDHAF2 X87 single residue sp:9 7.98189363303711e-21 9 kidney:9
PDGFRA D842 single residue V:9|D:1|H:1|I:1 1.11042381548794e-20 12 soft_tissue:8|brain:3|lung:1
TP53 Y126 single residue C:11|D:8|*:7|S:3|H:2|N:2 1.53812159511432e-20 33 breast:5|pancreas:5|bowel:4|head_neck:4|stomach:4|lung:3|prostate:3|liver:2|brain:1|lymph:1|soft_tissue:1
NFE2L2 T80 single residue R:5|K:4|A:3|P:2|I:1 2.59468886654441e-20 15 lung:3|uterus:3|bladder:2|kidney:2|head_neck:1|liver:1|ovary:1|stomach:1|thyroid:1
PIK3CA G1049 single residue R:16|A:1 2.7633032404138e-20 17 breast:7|bowel:3|uterus:3|bladder:1|kidney:1|lung:1|ovary:1
ESR1 L536 single residue H:6|P:3|L:2|R:2|Q:1 2.9652701136616e-20 14 breast:12|uterus:2
SF3B1 E902 single residue K:13|Q:3|G:1 3.68985777208901e-20 17 bladder:15|skin:2
TP53 A159 single residue V:27|P:23|A:1|D:1 4.57178660230022e-20 52 lung:20|bladder:5|bowel:4|skin:4|brain:3|head_neck:3|breast:2|ovary:2|pancreas:2|prostate:2|blood:1|bone:1|kidney:1|liver:1|stomach:1
TP53 I255 single residue F:12|N:7|S:6|T:6|I:1 6.05480414387033e-20 32 breast:6|bowel:3|brain:3|lung:3|pancreas:3|prostate:3|stomach:3|head_neck:2|uterus:2|biliary_tract:1|blood:1|liver:1|ovary:1
PPP6C R264 single residue C:19 1.18595587087755e-19 19 skin:17|lung:1|unk:1
PIK3CA Y1021 single residue C:11|H:3 1.32809167941191e-19 14 bowel:4|uterus:4|breast:2|stomach:2|prostate:1|skin:1
KIT K642 single residue E:12|N:1|Q:1 1.33539003985944e-19 14 skin:8|soft_tissue:2|testis:2|bowel:1|stomach:1
TP53 L194 single residue R:30|F:12|H:4|P:3 1.50602327108872e-19 49 lung:11|breast:9|pancreas:5|bladder:4|bowel:3|head_neck:3|ovary:3|brain:2|stomach:2|adrenal_gland:1|cervix:1|liver:1|lymph:1|skin:1|soft_tissue:1|thymus:1
PIK3R1 G376 single residue R:18 1.67548192695841e-19 18 brain:12|stomach:2|bowel:1|lung:1|skin:1|uterus:1
TP53 X224 single residue sp:39 2.23757783098521e-19 39 lung:8|stomach:6|head_neck:5|bowel:3|ovary:3|liver:2|pancreas:2|soft_tissue:2|blood:1|brain:1|breast:1|kidney:1|prostate:1|skin:1|thyroid:1|unk:1
PIK3CA R38 single residue H:11|C:8|G:1|L:1|S:1 3.16459873021845e-19 22 bowel:7|uterus:7|brain:3|stomach:2|cervix:1|lung:1|prostate:1
MET D1010 single residue H:6|N:6|Y:2 3.42669514641377e-19 14 lung:13|unk:1
ARID1A R1989 single residue *:28|Q:1 3.62855909355564e-19 29 uterus:14|bowel:7|lymph:2|bladder:1|cervix:1|head_neck:1|pancreas:1|stomach:1|unk:1
SPOP F102 single residue C:12|V:7|L:2|S:2|I:1 1.62286422111738e-18 24 prostate:22|bladder:1|lymph:1
PIK3CA N1044 single residue K:12|Y:2 1.63185954246621e-18 14 breast:5|kidney:2|prostate:2|unk:2|uterus:2|brain:1
MAX R60 single residue Q:21|R:1|W:1 1.63574150622726e-18 23 bowel:6|brain:6|uterus:3|lung:2|skin:2|blood:1|pancreas:1|stomach:1|unk:1
PPP2R1A S256 single residue F:11|Y:3 3.21769293190453e-18 14 uterus:11|bladder:1|breast:1|ovary:1
PIK3CA E81 single residue K:24|*:1 4.01643559943444e-18 25 breast:7|bowel:4|uterus:4|brain:2|head_neck:2|lung:2|cervix:1|kidney:1|skin:1|thyroid:1
FGFR2 C382 single residue R:14|Y:1 4.7730084036351e-18 15 uterus:7|stomach:3|biliary_tract:2|cervix:1|skin:1|testis:1
CDKN2A P114 single residue L:24|P:2|T:2|F:1|H:1|S:1 6.37256811718714e-18 31 skin:20|head_neck:4|unk:3|lung:2|bladder:1|pancreas:1
ESR1 E380 single residue Q:14 2.06583810918944e-17 14 breast:14
SMAD4 D351 single residue Y:6|N:5|G:3|H:3|V:2|A:1 2.31112791341444e-17 20 lung:6|bowel:5|stomach:4|pancreas:3|biliary_tract:1|prostate:1
ERBB3 K329 single residue E:9|T:2|R:1 3.29864591429092e-17 12 bladder:4|breast:3|bowel:2|head_neck:1|stomach:1|uterus:1
PIK3R1 K567 single residue E:12 3.34660265701711e-17 12 bowel:4|uterus:4|stomach:2|brain:1|lymph:1
CDKN2A D108 single residue Y:14|N:9|H:4|G:1|V:1 5.41040232412513e-17 29 bladder:12|lung:10|head_neck:4|biliary_tract:1|breast:1|ovary:1
KIT V559 single residue A:6|D:5|G:3 5.59843123930108e-17 14 soft_tissue:8|skin:3|bowel:1|breast:1|thymus:1
CDKN2A D84 single residue N:12|Y:6|G:3|V:3|A:1|D:1 6.27026193952657e-17 26 lung:7|stomach:5|bladder:4|biliary_tract:2|head_neck:2|pancreas:2|brain:1|breast:1|skin:1|unk:1
MTOR S2215 single residue Y:12|F:9|T:1 1.24086584913819e-16 22 bowel:5|kidney:4|uterus:4|lung:3|cervix:2|skin:2|brain:1|head_neck:1
TGFBR2 R553 single residue H:10|C:9|L:3|G:1 1.73780438735199e-16 23 bowel:13|pancreas:3|head_neck:2|breast:1|lung:1|skin:1|stomach:1|unk:1
SMAD2 S464 single residue *:21 2.59958573934364e-16 21 bowel:9|breast:4|stomach:3|bladder:1|kidney:1|lung:1|pancreas:1|prostate:1
RHEB Y35 single residue N:5|C:2|H:2|S:2|*:1 4.97821246870288e-16 12 kidney:4|uterus:3|testis:2|bladder:1|bowel:1|pancreas:1
TP53 X33 single residue sp:35 5.09683349058292e-16 35 bowel:7|lung:5|liver:4|head_neck:3|kidney:3|ovary:2|pancreas:2|stomach:2|bladder:1|breast:1|prostate:1|skin:1|soft_tissue:1|unk:1|uterus:1
KIT L576 single residue P:14 6.10110567747655e-16 14 soft_tissue:6|skin:4|testis:2|head_neck:1|vulva:1
KIT V654 single residue A:8 6.35339710250059e-16 8 soft_tissue:8
MTOR T1977 single residue K:7|I:3|R:3|S:1 7.60484276660308e-16 14 kidney:6|bowel:2|bladder:1|blood:1|lung:1|prostate:1|unk:1|uterus:1
TP53 F270 single residue L:8|V:8|S:6|C:4|I:4 1.26152260238551e-15 30 breast:8|lung:7|stomach:4|brain:2|ovary:2|bladder:1|bowel:1|head_neck:1|pancreas:1|prostate:1|skin:1|soft_tissue:1
H3F3A G35 single residue R:9|V:2|W:1 1.61532856518637e-15 12 brain:10|adrenal_gland:1|soft_tissue:1
RRAS2 Q72 single residue L:7|H:2 6.59079770930105e-15 9 uterus:4|lung:3|head_neck:1|prostate:1
PTEN R173 single residue H:17|C:14|P:1 1.02111146115902e-14 32 bowel:8|brain:8|uterus:6|prostate:2|biliary_tract:1|bladder:1|head_neck:1|lung:1|lymph:1|ovary:1|skin:1|soft_tissue:1
CREBBP Y1503 single residue H:4|N:2|C:1|D:1|S:1 1.40143294855795e-14 9 lymph:8|bladder:1
TP53 E258 single residue *:14|K:14|D:5|A:4|G:4|Q:4|E:1|V:1 1.50604967554599e-14 47 lung:11|pancreas:7|bladder:6|bowel:5|breast:4|brain:2|head_neck:2|liver:2|prostate:2|skin:2|stomach:2|ovary:1|unk:1
PIK3CA C901 single residue F:13 1.63044244852762e-14 13 uterus:4|brain:2|breast:2|biliary_tract:1|bone:1|bowel:1|head_neck:1|prostate:1
GATA3 M293 single residue K:8|R:1 1.77835401903853e-14 9 breast:9
CTNNB1 N387 single residue K:9|I:1|Y:1 2.74228910619457e-14 11 liver:4|pancreas:2|bowel:1|lung:1|prostate:1|skin:1|unk:1
ERBB4 Q707 single residue E:6|Q:5 2.78828635378649e-14 11 bladder:11
RET M918 single residue T:11 3.89383943076572e-14 11 thyroid:6|adrenal_gland:4|breast:1
CIC R202 single residue W:11|Q:2 8.48771778696607e-14 13 brain:11|prostate:1|soft_tissue:1
CDKN2A Q50 single residue *:16|H:4|R:3 9.45718518403517e-14 23 skin:13|pancreas:4|stomach:3|lung:2|head_neck:1
FOXA1 F266 single residue L:5|C:2|F:1|I:1|S:1|V:1 1.05845615051602e-13 11 prostate:9|breast:2
ERBB3 A232 single residue V:14|T:1 1.11785460538783e-13 15 bowel:5|stomach:3|biliary_tract:1|breast:1|head_neck:1|lung:1|pancreas:1|prostate:1|unk:1
RB1 X405 single residue sp:19 1.54376720926398e-13 19 bladder:6|lung:5|brain:3|prostate:2|ovary:1|soft_tissue:1|uterus:1
SPOP W131 single residue G:12|C:4|L:3|S:3|R:1 1.9688757329735e-13 23 prostate:21|brain:1|uterus:1
SPOP Y87 single residue N:8|S:3|C:2|D:1 1.9688757329735e-13 14 prostate:14
MTOR I2500 single residue F:5|M:4|N:1 2.29333311583453e-13 10 kidney:2|adrenal_gland:1|breast:1|head_neck:1|lung:1|skin:1|stomach:1|unk:1|uterus:1
SMARCB1 R377 single residue H:11|C:5|L:1 2.32553910162698e-13 17 stomach:4|bowel:3|brain:2|lung:2|biliary_tract:1|breast:1|kidney:1|liver:1|skin:1|soft_tissue:1
PIK3CB D1067 single residue V:8|Y:3|A:1|H:1 2.84754684617547e-13 13 kidney:3|skin:3|lung:2|brain:1|head_neck:1|testis:1|thyroid:1|uterus:1
PIK3R1 X582 single residue sp:14 3.86307734142432e-13 14 brain:5|prostate:3|uterus:3|bowel:2|kidney:1
VHL X114 single residue sp:16 4.1399817297452e-13 16 kidney:16
FGFR3 G370 single residue C:8 4.34020637676127e-13 8 bladder:8
SF3B1 K666 single residue T:5|N:3|E:2|M:2|Q:1 7.28542711318273e-13 13 lung:3|blood:2|eye:2|unk:2|breast:1|liver:1|pancreas:1|skin:1
VHL S65 single residue *:7|L:6|P:2|T:1|W:1 7.40697442383436e-13 17 kidney:15|bladder:1|pancreas:1
CDK4 K22 single residue M:5|Q:2 8.18881825213307e-13 7 skin:6|blood:1
TP53 F134 single residue L:12|V:5|C:4|I:2|S:1 8.60419732135027e-13 24 lung:4|stomach:4|breast:3|pancreas:3|skin:3|bowel:1|head_neck:1|lymph:1|ovary:1|prostate:1|unk:1|uterus:1
KIT W557 single residue R:6|G:3|S:2|C:1 9.16539228195011e-13 12 testis:5|soft_tissue:4|skin:1|thymus:1|unk:1
EGFR R222 single residue C:15|H:1 1.97405001559138e-12 16 brain:13|bowel:1|breast:1|skin:1
EGFR R252 single residue C:9|H:4|P:3 1.97405001559138e-12 16 brain:12|stomach:2|bowel:1|prostate:1
FGFR3 K650 single residue E:7|M:1|N:1|T:1 2.00679702410257e-12 10 bladder:4|brain:2|skin:2|blood:1|kidney:1
SMARCA4 G1232 single residue S:11|C:2|D:2|V:2 2.11467605706404e-12 17 lung:5|brain:3|stomach:3|kidney:2|lymph:1|skin:1|soft_tissue:1|unk:1
ARID2 S297 single residue F:16|S:4 2.22766268353864e-12 20 skin:15|unk:5
HIST1H1C A180 single residue A:21|P:1 3.16251091470805e-12 22 breast:8|bladder:6|lung:5|head_neck:1|lymph:1|thymus:1
ERBB3 G284 single residue R:13 4.0960348053e-12 13 bowel:3|stomach:3|bladder:2|biliary_tract:1|breast:1|cervix:1|unk:1|uterus:1
ERBB2 D769 single residue Y:12|H:6 4.15162464558809e-12 18 stomach:7|breast:5|bladder:3|bowel:1|cervix:1|ovary:1
PTEN X70 single residue sp:15 5.42733937707976e-12 15 breast:4|uterus:4|thyroid:2|brain:1|lung:1|prostate:1|skin:1|unk:1
STK11 E223 single residue *:13|K:1|V:1 5.43755738494477e-12 15 lung:13|ampulla_of_vater:1|unk:1
FGFR1 K687 single residue E:8|*:1|K:1|N:1 6.61101232218435e-12 11 brain:6|bladder:1|blood:1|liver:1|lung:1|soft_tissue:1
SOX17 S403 single residue I:8 7.18958994628799e-12 8 uterus:7|ovary:1
VHL X155 single residue sp:14 7.83200669499252e-12 14 kidney:14
NUP93 E14 single residue K:16 8.46294727163906e-12 16 breast:9|lung:3|bladder:2|head_neck:1|thyroid:1
STK11 X155 single residue sp:14 1.05267328502366e-11 14 lung:13|bowel:1
STK11 X245 single residue sp:13 1.05267328502366e-11 13 lung:12|cervix:1
TP53 M246 single residue V:16|I:10|K:3|L:3|T:3|R:2 1.10580578627633e-11 37 lung:10|brain:5|breast:3|prostate:3|stomach:3|bladder:2|head_neck:2|kidney:2|pancreas:2|soft_tissue:2|biliary_tract:1|bowel:1|thyroid:1
TP53 R110 single residue L:25|P:11|C:6|H:1 1.12989197548727e-11 43 lung:13|head_neck:5|bowel:3|stomach:3|ovary:2|pancreas:2|prostate:2|soft_tissue:2|bladder:1|brain:1|breast:1|kidney:1|liver:1|lymph:1|skin:1|thymus:1|thyroid:1|unk:1|vulva:1
APC Q1429 single residue *:22|R:1 1.21477020884371e-11 23 bowel:22|ovary:1
PTEN C136 single residue R:9|F:2|Y:2|*:1 1.52906668939568e-11 14 uterus:4|brain:3|breast:2|bowel:1|head_neck:1|kidney:1|lung:1|skin:1
PTEN G132 single residue D:8|A:3|S:3|V:3 1.52906668939568e-11 17 brain:8|uterus:3|prostate:2|bowel:1|lung:1|skin:1|soft_tissue:1
CCND1 Y44 single residue D:3|*:1|C:1|F:1|H:1|S:1 1.6522455227078e-11 8 lymph:7|blood:1
SMARCA4 R1192 single residue C:9|H:7|P:1 1.6996864443455e-11 17 brain:4|stomach:3|lung:2|skin:2|bladder:1|breast:1|kidney:1|liver:1|pancreas:1|uterus:1
INPPL1 A1185 single residue D:11 1.76182303850515e-11 11 adrenal_gland:4|prostate:2|bladder:1|brain:1|head_neck:1|soft_tissue:1|stomach:1
SMAD4 P356 single residue L:10|S:3|R:2|H:1 2.1533538671879e-11 16 bowel:9|stomach:4|biliary_tract:1|lung:1|pancreas:1
ERBB3 S846 single residue I:10 2.5930810120753e-11 10 bowel:3|stomach:3|ampulla_of_vater:1|bladder:1|breast:1|lung:1
CDKN2A X51 single residue sp:20 3.09188955285343e-11 20 skin:6|head_neck:4|liver:3|bladder:2|lung:2|biliary_tract:1|bone:1|unk:1
STK11 D194 single residue Y:7|N:3|V:2|G:1|H:1 3.49153886629741e-11 14 lung:11|breast:1|head_neck:1|prostate:1
FBXW7 R658 single residue *:15|Q:4|R:1 3.79187313312857e-11 20 bowel:7|uterus:6|cervix:2|bladder:1|brain:1|head_neck:1|lung:1|skin:1
AR W742 single residue C:6|L:1 4.10229788253528e-11 7 prostate:7
TP53 V143 single residue M:12|A:7|G:5|E:2 5.17740247574383e-11 26 skin:4|bowel:3|lung:3|head_neck:2|liver:2|pancreas:2|bladder:1|brain:1|breast:1|kidney:1|lymph:1|ovary:1|prostate:1|soft_tissue:1|stomach:1|uterus:1
CCND1 P287 single residue S:5|L:4|A:1|R:1|T:1 5.65945826265419e-11 12 uterus:6|head_neck:2|bladder:1|bowel:1|cervix:1|skin:1
CIC R1512 single residue H:5|L:3|C:2|S:1 6.01782827522399e-11 11 brain:9|bladder:1|breast:1
FBXW7 R689 single residue W:14|Q:5 6.54359310325598e-11 19 bowel:6|uterus:6|brain:3|breast:1|head_neck:1|lung:1|unk:1
MAP2K1 E203 single residue K:14|V:2 6.86894927003352e-11 16 skin:6|brain:2|bladder:1|blood:1|bowel:1|breast:1|lung:1|pancreas:1|stomach:1|unk:1
FOXA1 I176 single residue V:7|M:4 7.65741901652142e-11 11 breast:10|lung:1
DICER1 E1813 single residue G:6|Q:3|A:1|K:1 1.03770440524625e-10 11 bowel:3|uterus:3|thyroid:2|brain:1|ovary:1|skin:1
PTPN11 E76 single residue K:7|G:3|A:2|Q:1 1.05060575176458e-10 13 brain:7|blood:2|bowel:2|lung:2
KNSTRN S24 single residue F:13 1.46994689964654e-10 13 skin:13
NF1 R440 single residue *:17|Q:2 1.55777425916696e-10 19 skin:10|unk:3|bowel:2|uterus:2|brain:1|breast:1
EGFR L747 single residue L:3|P:3|F:1|S:1 1.56584028674065e-10 8 lung:8
ACVR1 G328 single residue E:5|V:2 2.17276202583146e-10 7 brain:7
CCND1 T286 single residue I:8|A:1 2.39494812952936e-10 9 uterus:6|bladder:1|bowel:1|stomach:1
VHL L89 single residue H:9|P:5|L:1 2.84655898510653e-10 15 kidney:13|bladder:1|lung:1
NOTCH2 T235 single residue S:10 2.89150962196842e-10 10 lymph:5|biliary_tract:2|kidney:1|soft_tissue:1|thymus:1
CIC R1515 single residue C:5|H:5 3.21216725843384e-10 10 brain:9|bowel:1
NFE2L2 L30 single residue F:7|H:2|P:2|R:1 3.26181329917381e-10 12 head_neck:4|kidney:2|lung:2|liver:1|pancreas:1|soft_tissue:1|stomach:1
TP53 S127 single residue F:31|Y:10|P:4|C:1|S:1|T:1 3.33046155258552e-10 48 bowel:8|lung:8|skin:6|brain:4|head_neck:4|ovary:3|pancreas:3|stomach:3|bladder:2|breast:2|unk:2|uterus:2|prostate:1
SF3B1 N626 single residue Y:4|D:2|H:2 3.34579354448327e-10 8 blood:3|skin:2|breast:1|lung:1|uterus:1
EGFR E709 single residue K:13|A:2|Q:1 3.57278117431548e-10 16 lung:9|brain:3|bladder:1|breast:1|ovary:1|skin:1
TP53 Q136 single residue *:16|E:10|P:3|H:1|L:1 3.67041636006903e-10 31 breast:6|head_neck:6|brain:5|skin:3|liver:2|bladder:1|bowel:1|kidney:1|lung:1|ovary:1|pancreas:1|penis:1|soft_tissue:1|stomach:1
ERBB3 H228 single residue Q:6|R:2 4.40384663213664e-10 8 bladder:6|stomach:2
TP53 C277 single residue F:20|*:3|Y:3|G:1|W:1 5.26918784417401e-10 28 lung:8|brain:3|stomach:3|bladder:2|bone:2|unk:2|biliary_tract:1|blood:1|bowel:1|breast:1|head_neck:1|liver:1|ovary:1|thyroid:1
APC Q1367 single residue *:28|E:1 5.92530901182497e-10 29 bowel:28|lung:1
ERCC2 T484 single residue A:4|M:4 5.94542228261946e-10 8 bladder:7|liver:1
MYOD1 L122 single residue R:5|L:1|M:1 6.09833928477344e-10 7 soft_tissue:5|lung:2
ERG R354 single residue R:6 7.20192472847528e-10 6 prostate:6
TP53 W91 single residue *:35 7.29139525931587e-10 35 lung:6|stomach:6|bladder:3|bowel:3|breast:3|pancreas:3|brain:2|skin:2|soft_tissue:2|biliary_tract:1|head_neck:1|kidney:1|prostate:1|unk:1
ARID1A R693 single residue *:16 8.62350035432213e-10 16 uterus:7|stomach:3|bowel:2|bladder:1|brain:1|breast:1|thyroid:1
FOXA1 H247 single residue Y:4|R:3|Q:2|L:1 8.78143675660237e-10 10 prostate:7|breast:3
GNAS Q227 single residue H:4|L:4|K:3 9.92974560347528e-10 11 lung:6|bowel:1|liver:1|ovary:1|skin:1|thyroid:1
PARP1 G500 single residue G:6 1.14977828803329e-09 6 stomach:6
CTNNB1 H36 single residue P:7|Y:1 1.23306160353623e-09 8 liver:7|skin:1
NFE2L2 W24 single residue R:7|C:3|S:1 1.25844116981492e-09 11 lung:3|head_neck:2|kidney:2|bladder:1|liver:1|skin:1|stomach:1
HRAS K117 single residue N:8|R:1 1.3704997221253e-09 9 bladder:4|thymus:3|breast:1|head_neck:1
KDM6A Q555 single residue *:16 1.37232724382867e-09 16 bladder:16
TP53 E298 single residue *:36|Q:1 1.49796774432529e-09 37 lung:18|head_neck:7|stomach:3|breast:2|prostate:2|unk:2|pancreas:1|skin:1|soft_tissue:1
ARID1A R2158 single residue *:12|Q:2|R:1 1.61815343802636e-09 15 bowel:3|stomach:3|lung:2|skin:2|uterus:2|bladder:1|head_neck:1|liver:1
B2M X23 single residue sp:17 1.71517108741211e-09 17 bowel:9|lymph:3|skin:2|stomach:2|lung:1
ATM R3008 single residue H:7|C:6|L:2 1.74669303192438e-09 15 bowel:6|lung:3|lymph:2|pancreas:2|bladder:1|stomach:1
EGFR L62 single residue R:10 1.90253284860552e-09 10 brain:6|lung:4
KIT D820 single residue Y:4|V:3|E:2|A:1|G:1 1.92130177530644e-09 11 soft_tissue:6|testis:2|unk:2|penis:1
PTEN D92 single residue E:7|G:3|H:2|N:2|V:2|Y:2 2.81113657455673e-09 18 breast:4|uterus:4|brain:3|bowel:2|lung:2|head_neck:1|ovary:1|soft_tissue:1
NFE2L2 Q26 single residue K:4|P:2|H:1|L:1|R:1 2.81197869371358e-09 9 lung:4|liver:2|breast:1|stomach:1|uterus:1
TET1 P1752 single residue P:8|S:2 2.87599149463378e-09 10 skin:10
FGFR4 V550 single residue L:7|M:4 2.94821142153483e-09 11 breast:6|soft_tissue:4|uterus:1
KRAS A59 single residue T:5|G:4|A:2|E:1 3.18311796039066e-09 12 blood:3|lung:3|bowel:2|stomach:2|kidney:1|prostate:1
PTEN X343 single residue sp:15 3.31241208014574e-09 15 lung:4|uterus:3|kidney:2|bladder:1|brain:1|breast:1|cervix:1|ovary:1|unk:1
DIS3 D488 single residue N:7|A:1|G:1|H:1|Y:1 3.46224146992256e-09 11 blood:4|lung:4|brain:1|head_neck:1|kidney:1
CDH1 D254 single residue N:5|Y:4|E:2 3.46819951743406e-09 11 stomach:9|bowel:1|penis:1
CDKN2A E88 single residue *:18|K:8|E:1 3.70241974704799e-09 27 skin:10|head_neck:7|unk:4|pancreas:2|brain:1|cervix:1|lung:1|soft_tissue:1
MYD88 S243 single residue N:7 4.78040181622355e-09 7 lymph:6|breast:1
PIK3CA G1007 single residue R:9|D:1 5.22206675389205e-09 10 bowel:2|breast:2|bladder:1|cervix:1|head_neck:1|kidney:1|lung:1|uterus:1
PTEN Y68 single residue H:6|*:2|C:2|N:1 5.27636707238447e-09 11 bowel:4|brain:3|uterus:2|breast:1|prostate:1
GNAQ T96 single residue S:9 6.19698434219041e-09 9 kidney:2|lymph:2|biliary_tract:1|liver:1|lung:1|pancreas:1|prostate:1
SETD2 R1625 single residue C:6|H:5|L:1|S:1 6.83579094550133e-09 13 kidney:3|lung:3|skin:3|brain:1|breast:1|thyroid:1|uterus:1
SDHA L639 single residue V:7 7.18357325737371e-09 7 lymph:6|brain:1
PIK3CA T1025 single residue A:7|S:1 8.49323741228694e-09 8 uterus:4|bowel:2|breast:2
SOS1 N233 single residue Y:7 9.34176359993697e-09 7 lung:4|uterus:3
PIK3CA C378 single residue F:4|R:3|Y:2 9.90900884246927e-09 9 brain:2|breast:2|uterus:2|ovary:1|pancreas:1|stomach:1
FOXA1 M253 single residue K:4|R:2|T:1 1.06201814393352e-08 7 prostate:6|breast:1
ARID1A R1276 single residue *:14|Q:1 1.08597311260384e-08 15 uterus:4|bowel:3|stomach:2|unk:2|bladder:1|blood:1|lymph:1|pancreas:1
PTEN X212 single residue sp:19 1.13062485515142e-08 19 breast:4|brain:3|uterus:3|bowel:2|cervix:1|head_neck:1|kidney:1|liver:1|lung:1|pancreas:1|prostate:1
EIF1AX G9 single residue D:6|R:3|V:2 1.14561094279715e-08 11 thyroid:4|eye:2|lung:2|bowel:1|head_neck:1|ovary:1
FGFR3 G380 single residue R:11 1.20520209570854e-08 11 bladder:5|head_neck:3|breast:1|skin:1|stomach:1
FBXW7 R367 single residue *:16|P:1 1.29019937681228e-08 17 bowel:9|stomach:2|cervix:1|head_neck:1|lung:1|pancreas:1|soft_tissue:1|uterus:1
TCF7L2 R471 single residue C:8|H:4|S:2 1.30421488952988e-08 14 bowel:13|stomach:1
RHOA R5 single residue Q:8|W:8|L:1 1.52155472277533e-08 17 stomach:8|lymph:6|breast:2|bowel:1
PIK3CA D350 single residue N:6|G:5|V:1 2.16867928564548e-08 12 bowel:2|breast:2|uterus:2|brain:1|head_neck:1|lung:1|pancreas:1|skin:1|stomach:1
MAP2K1 G128 single residue D:5|V:4|R:1 2.50287570681096e-08 10 bowel:4|lung:2|skin:2|biliary_tract:1|stomach:1
PTEN H93 single residue R:6|Y:4|L:1|P:1 2.90249120822907e-08 12 uterus:3|brain:2|breast:2|bladder:1|bowel:1|head_neck:1|skin:1|soft_tissue:1
SF3B1 K741 single residue N:5|E:2|*:1|Q:1|T:1 3.09082474257009e-08 10 liver:3|lung:2|blood:1|breast:1|kidney:1|prostate:1|skin:1
BRAF L597 single residue Q:3|R:3|S:2|L:1|V:1 3.69731390598529e-08 10 skin:6|blood:1|brain:1|prostate:1|uterus:1
RAC1 A178 single residue V:12 4.64277494505764e-08 12 head_neck:6|bowel:2|brain:1|cervix:1|lung:1|soft_tissue:1
VHL S80 single residue R:5|N:4|I:1|S:1 4.73394777910565e-08 11 kidney:10|pancreas:1
NF1 R2450 single residue *:16|Q:1 5.45596275682394e-08 17 uterus:5|brain:4|bowel:3|bladder:2|breast:1|cervix:1|head_neck:1
RB1 R251 single residue *:15|Q:1 5.87879104509438e-08 16 bladder:4|lung:3|head_neck:2|stomach:2|brain:1|breast:1|skin:1|unk:1|uterus:1
RB1 R320 single residue *:14 5.87879104509438e-08 14 lung:2|pancreas:2|uterus:2|bladder:1|breast:1|head_neck:1|kidney:1|ovary:1|skin:1|stomach:1|unk:1
PIK3CB E1051 single residue K:9|G:2 5.95653540276479e-08 11 kidney:2|prostate:2|biliary_tract:1|bladder:1|bowel:1|breast:1|lung:1|soft_tissue:1|stomach:1
ACVR1 R258 single residue G:5|M:1 6.8256854220096e-08 6 brain:5|stomach:1
APC Q1378 single residue *:23 6.87808957232797e-08 23 bowel:23
TP63 R379 single residue C:14|H:2|S:1 8.73352761228577e-08 17 skin:14|blood:1|bowel:1|unk:1
MAX H28 single residue R:6 8.97388616000743e-08 6 uterus:5|testis:1
ERCC2 Y24 single residue C:5 9.89549248621122e-08 5 bladder:5
PTPN11 Q510 single residue L:5|H:3|E:1 1.01220941991159e-07 9 blood:3|brain:3|skin:2|soft_tissue:1
SMAD4 R445 single residue *:16|Q:1 1.11424475801292e-07 17 pancreas:5|bowel:4|stomach:2|biliary_tract:1|bladder:1|breast:1|cervix:1|skin:1|unk:1
RAF1 S259 single residue F:7|P:3|C:1|S:1 1.11523704110657e-07 12 lung:3|skin:3|biliary_tract:1|bladder:1|bowel:1|head_neck:1|lymph:1|unk:1
ARAF S214 single residue F:4|A:3|P:2|C:1|S:1|Y:1 1.11680470351445e-07 12 lung:5|kidney:2|skin:2|biliary_tract:1|blood:1|bowel:1
TP53 G154 single residue V:23|C:1|D:1 1.14503702283721e-07 25 lung:17|bowel:3|bladder:1|liver:1|pancreas:1|stomach:1|unk:1
MYC P74 single residue L:4|S:4|T:2|Q:1|R:1 1.17925450406565e-07 12 lung:4|skin:2|soft_tissue:2|blood:1|head_neck:1|lymph:1|uterus:1
TP53 X332 single residue sp:48 1.24919927952202e-07 48 lung:8|breast:6|head_neck:5|bladder:4|brain:4|uterus:4|bowel:3|liver:3|ovary:3|skin:2|stomach:2|biliary_tract:1|lymph:1|prostate:1|soft_tissue:1
ETV6 X11 single residue sp:5 1.46221405832525e-07 5 lymph:5
PIK3CA P104 single residue L:10|R:1 1.61020365998658e-07 11 breast:3|skin:2|uterus:2|brain:1|head_neck:1|lung:1|ovary:1
CTCF R377 single residue C:9|H:3 1.65354504881555e-07 12 uterus:8|bowel:2|skin:2
TP53 L130 single residue V:13|F:10|R:4|P:2|H:1 2.06448059790326e-07 30 bowel:5|brain:5|pancreas:5|stomach:5|lung:4|ovary:2|breast:1|liver:1|prostate:1|unk:1
STAG2 R216 single residue *:11|Q:2|R:1 2.21331571472827e-07 14 bladder:6|bone:2|biliary_tract:1|brain:1|kidney:1|lung:1|unk:1|uterus:1
FGFR3 S371 single residue C:5 2.53645379864409e-07 5 bladder:5
SF3B1 G742 single residue D:8 2.57040955470615e-07 8 blood:5|cervix:1|kidney:1|lung:1
RB1 X500 single residue sp:10 2.59331922255693e-07 10 bladder:2|lung:2|cervix:1|head_neck:1|kidney:1|liver:1|skin:1|soft_tissue:1
CDK6 L65 single residue L:9 2.88833961402471e-07 9 bladder:8|cervix:1
TP53 Q317 single residue *:32 3.10292683399654e-07 32 lung:7|skin:6|stomach:5|bladder:2|ovary:2|unk:2|blood:1|bone:1|bowel:1|brain:1|breast:1|head_neck:1|pancreas:1|soft_tissue:1
TGFBR1 S241 single residue L:12|S:2|*:1 3.26275109634539e-07 15 bowel:9|ampulla_of_vater:1|biliary_tract:1|ovary:1|pancreas:1|stomach:1|uterus:1
CDKN2A E120 single residue *:16|D:1|K:1 3.4869234152267e-07 18 head_neck:5|lung:4|stomach:3|pancreas:2|brain:1|kidney:1|liver:1|skin:1
PAX5 V26 single residue G:9 3.7223934800935e-07 9 bowel:3|stomach:3|head_neck:1|pleura:1|prostate:1
STAT3 H410 single residue R:4|P:2 3.91618125206497e-07 6 liver:4|breast:1|lung:1
TP63 X194 single residue sp:5 3.99900800749029e-07 5 head_neck:5
FBXW7 S582 single residue L:10|P:1|S:1 4.01507799087038e-07 12 bowel:10|lung:1|stomach:1
RHOA A161 single residue V:5|T:2 4.19520880623079e-07 7 bladder:6|lymph:1
EP300 Y1414 single residue C:6|D:1 4.30606176073522e-07 7 lung:3|bladder:2|head_neck:1|stomach:1
ERBB3 E332 single residue K:13|Q:1 4.75403254856063e-07 14 bladder:10|lung:2|cervix:1|stomach:1
EP300 W1466 single residue L:3|C:2|*:1|G:1|R:1 4.82359795206628e-07 8 bowel:4|stomach:2|head_neck:1|lymph:1
EP300 Y1467 single residue D:2|N:2|C:1|H:1|K:1|S:1 4.82359795206628e-07 8 lymph:3|head_neck:2|bladder:1|brain:1|uterus:1
MET V1070 single residue A:2|E:2|R:1 5.23737105519572e-07 5 kidney:5
MET M1250 single residue T:6 5.23737105519572e-07 6 kidney:5|unk:1
ATM R250 single residue *:14|P:1 5.72626267800822e-07 15 bowel:5|uterus:4|bladder:2|skin:2|kidney:1|prostate:1
PIK3CA M1 single residue V:6 6.05536749909866e-07 6 brain:5|uterus:1
SDHA S445 single residue S:9|L:1 7.30147582086515e-07 10 lymph:6|bladder:1|breast:1|prostate:1|stomach:1
SMAD4 G419 single residue W:4|V:3|R:1 7.34281451772137e-07 8 bowel:7|stomach:1
PIK3R1 R348 single residue *:16 7.67867632604416e-07 16 uterus:8|bowel:7|breast:1
SMARCA4 M781 single residue I:6|V:2|L:1 8.44219689247448e-07 9 brain:3|stomach:3|biliary_tract:1|lung:1|pancreas:1
FOXA1 R261 single residue G:4|C:3|H:1|S:1 8.57798327208341e-07 9 prostate:8|bladder:1
FBXW7 Y545 single residue C:6|*:1 9.29532572203721e-07 7 stomach:3|bowel:1|breast:1|head_neck:1|uterus:1
ERBB4 L798 single residue R:7|P:2|H:1|L:1 1.05290421298124e-06 11 stomach:8|bladder:1|bowel:1|kidney:1
VHL S111 single residue N:6|R:2|P:1|S:1 1.145547139501e-06 10 kidney:10
KIT Y823 single residue D:5|C:1 1.19299853504738e-06 6 soft_tissue:3|testis:2|bowel:1
RB1 X474 single residue sp:9 1.34474780240449e-06 9 lung:4|skin:3|bowel:1|brain:1
BCL6 R594 single residue Q:10|G:2 1.36919837925192e-06 12 bowel:7|bladder:2|uterus:2|head_neck:1
CDH1 X278 single residue sp:6 1.38818265516344e-06 6 breast:6
ARID1A R1721 single residue *:13 1.45530511496136e-06 13 bowel:3|stomach:3|uterus:2|biliary_tract:1|brain:1|liver:1|lung:1|skin:1
U2AF1 Q157 single residue P:2|R:2 1.6150389142363e-06 4 blood:4
ATM N2875 single residue S:5|T:2|K:1 1.70075948226044e-06 8 prostate:3|bowel:2|liver:2|breast:1
PTPN11 E69 single residue K:9|D:2 1.80787202544705e-06 11 brain:6|bowel:2|breast:2|stomach:1
FUBP1 R430 single residue C:11|H:1 1.92218538564378e-06 12 uterus:6|bowel:2|breast:1|cervix:1|prostate:1|stomach:1
MTOR F1888 single residue I:4|L:3|V:1 1.9720024293449e-06 8 kidney:5|uterus:2|bowel:1
MTOR L2427 single residue Q:4|R:3 1.9720024293449e-06 7 kidney:5|brain:1|uterus:1
FBXW7 G423 single residue V:8|*:1|A:1 2.07099491720386e-06 10 uterus:5|bowel:2|blood:1|head_neck:1|skin:1
CDKN2A X153 single residue sp:16 2.19076953414902e-06 16 head_neck:10|stomach:3|skin:2|lung:1
APC E1397 single residue *:19 2.58293837594006e-06 19 bowel:19
APC Y935 single residue *:13 2.58293837594006e-06 13 bowel:13
EPAS1 P531 single residue L:2|A:1|S:1 2.7458396480587e-06 4 adrenal_gland:4
PTEN Y27 single residue D:4|C:2|N:2|*:1|H:1 2.97185296362565e-06 10 brain:3|uterus:2|bowel:1|breast:1|ovary:1|stomach:1|thyroid:1
VHL N78 single residue S:4|D:2|Y:2|K:1 3.06267165122873e-06 9 kidney:8|pancreas:1
ACVR1 R206 single residue H:8 3.09527109977675e-06 8 uterus:6|brain:2
AKT1 L52 single residue R:4|H:1 3.30992340624556e-06 5 breast:4|kidney:1
IL7R K395 single residue R:4|T:3|K:2|N:2|M:1 3.44668089191901e-06 12 stomach:6|skin:2|bladder:1|bowel:1|lung:1|uterus:1
SMARCA4 R1189 single residue Q:7|G:3|*:1|L:1 3.57045753293949e-06 12 bladder:2|brain:2|head_neck:2|unk:2|bowel:1|lung:1|pancreas:1|skin:1
PTPN11 G503 single residue V:8|G:1 3.59243867419399e-06 9 lung:3|stomach:3|bladder:1|blood:1|bowel:1
ARID1A G2087 single residue R:10|E:3 3.82110215304271e-06 13 stomach:5|bowel:2|skin:2|cervix:1|lung:1|pancreas:1|uterus:1
CASP8 R292 single residue W:9|Q:4 4.27696951759218e-06 13 head_neck:4|breast:3|skin:2|bladder:1|lymph:1|unk:1|uterus:1
TP53 P152 single residue L:28|P:2|R:2|S:2|T:2|K:1|Q:1 4.46613497758463e-06 38 bowel:10|lung:8|bladder:3|brain:3|pancreas:3|stomach:3|head_neck:2|breast:1|lymph:1|prostate:1|skin:1|soft_tissue:1|unk:1
STK11 X307 single residue sp:8 4.6367505963321e-06 8 lung:8
RB1 R552 single residue *:13 4.65060954412826e-06 13 stomach:3|brain:2|lung:2|biliary_tract:1|bladder:1|bowel:1|breast:1|liver:1|soft_tissue:1
ARID1A R1335 single residue *:12 4.97635912481126e-06 12 uterus:4|bowel:2|stomach:2|bladder:1|brain:1|breast:1|lung:1
MTOR E1799 single residue K:12 5.32869235354167e-06 12 bowel:3|uterus:2|blood:1|brain:1|breast:1|cervix:1|lymph:1|prostate:1|skin:1
KMT2D R5179 single residue H:5|C:2|L:2|P:1 5.54656680344052e-06 10 bladder:2|lung:2|breast:1|liver:1|skin:1|stomach:1|thyroid:1|uterus:1
EZH2 K515 single residue R:8 5.87241204357667e-06 8 testis:3|brain:2|skin:1|soft_tissue:1|thymus:1
ERBB3 M91 single residue I:12 5.89385412710216e-06 12 bladder:9|breast:1|head_neck:1|uterus:1
PBRM1 R1160 single residue *:11|P:1|Q:1 6.01371567508865e-06 13 kidney:4|bowel:3|uterus:3|prostate:1|skin:1|stomach:1
SPOP M117 single residue V:7 6.81660266090703e-06 7 uterus:6|cervix:1
PIK3CD E1021 single residue K:8 7.49932571758753e-06 8 lymph:4|skin:2|bladder:1|unk:1
TP53 H168 single residue R:12|L:4|P:2|Y:1 7.59679170174124e-06 19 bowel:5|lung:4|stomach:3|brain:2|bone:1|breast:1|head_neck:1|liver:1|pancreas:1
CCND3 I290 single residue K:3|R:1 7.73194808545737e-06 4 lymph:4
TP53 W146 single residue *:24|C:1|G:1|S:1 8.41645737021107e-06 27 brain:4|lung:4|ovary:3|skin:3|stomach:3|bladder:2|breast:2|prostate:2|uterus:2|bowel:1|pancreas:1
TP53 R267 single residue W:15|P:8|L:5|Q:4|G:3|R:1 8.41645737021107e-06 36 lung:10|bowel:8|brain:8|liver:2|stomach:2|blood:1|breast:1|head_neck:1|kidney:1|ovary:1|skin:1
TP53 A161 single residue T:12|D:7|S:4|V:2|P:1 8.6597657861634e-06 26 bladder:6|lung:4|pancreas:4|bowel:3|breast:3|head_neck:2|brain:1|liver:1|ovary:1|prostate:1
SMO L412 single residue F:5|L:1 8.71010004332757e-06 6 brain:5|bladder:1
RB1 X830 single residue sp:11 9.08044118841068e-06 11 bladder:4|brain:3|lung:2|skin:1|uterus:1
PIK3CA E365 single residue K:11|V:2 9.15583894618766e-06 13 bladder:3|breast:3|bowel:2|uterus:2|brain:1|head_neck:1|stomach:1
CTCF R448 single residue *:8 1.11848029874604e-05 8 uterus:6|blood:1|head_neck:1
EP300 X1429 single residue sp:6 1.24478126439434e-05 6 kidney:4|head_neck:1|lung:1
PRKCI R480 single residue C:5|S:3|H:2 1.24954912334541e-05 10 bowel:6|stomach:3|ovary:1
PIK3R2 G373 single residue R:9 1.37716918085153e-05 9 uterus:3|ampulla_of_vater:1|bladder:1|bowel:1|breast:1|lung:1|stomach:1
PIK3R2 D557 single residue Y:5|N:2|G:1|H:1 1.37716918085153e-05 9 breast:2|prostate:2|bladder:1|head_neck:1|lung:1|testis:1|uterus:1
SMAD4 G352 single residue E:3|R:3|A:2|*:1|L:1|V:1 1.37739318604283e-05 11 lung:3|stomach:3|bowel:2|ampulla_of_vater:1|biliary_tract:1|pancreas:1
PTPRT E548 single residue K:11|G:1 1.45349357736284e-05 12 skin:11|ovary:1
TP53 K164 single residue E:9|*:4 1.47223833465579e-05 13 lung:5|bowel:2|ovary:2|bladder:1|brain:1|breast:1|stomach:1
MET F1200 single residue I:3|V:1 1.50401186839176e-05 4 kidney:4
ERCC2 Y72 single residue C:4 1.6086225598154e-05 4 bladder:4
CTCF Y226 single residue C:4 1.65503913101184e-05 4 breast:4
RHOA E47 single residue K:11 1.69502190537709e-05 11 bladder:8|head_neck:1|skin:1|soft_tissue:1
APC Q1406 single residue *:18|H:1 1.71142192081097e-05 19 bowel:17|bladder:1|skin:1
SMAD4 Q534 single residue *:9|P:1 1.79003182508512e-05 10 stomach:3|bowel:2|lung:2|pancreas:2|unk:1
ERBB2 L869 single residue R:4 1.8308455270165e-05 4 breast:4
STK11 S216 single residue F:11|S:1 1.94249168129621e-05 12 lung:8|biliary_tract:1|bladder:1|head_neck:1|skin:1
KNSTRN V12 single residue G:3|V:2 2.11447649416683e-05 5 stomach:4|lung:1
CTNNB1 I35 single residue S:7|I:1 2.1250479736793e-05 8 liver:3|skin:2|uterus:2|lung:1
TP53 Q144 single residue *:17|P:3|L:2|H:1 2.17738171086558e-05 23 lung:12|head_neck:2|bladder:1|bowel:1|breast:1|liver:1|ovary:1|pancreas:1|stomach:1|unk:1|uterus:1
MET Y1230 single residue H:2|C:1|S:1 2.26527320268023e-05 4 kidney:4
TP53 F109 single residue S:6|C:5|V:3|F:1|I:1 2.36567137864909e-05 16 skin:4|brain:3|bowel:2|ovary:2|stomach:2|lung:1|lymph:1|soft_tissue:1
KIT V560 single residue D:3|V:2|A:1|G:1 2.5201075105254e-05 7 soft_tissue:4|lung:1|stomach:1|testis:1
TP53 G105 single residue C:13|V:6|D:4|R:2|S:2|G:1 2.55614724011675e-05 28 lung:12|head_neck:4|ovary:4|bladder:1|bowel:1|brain:1|liver:1|prostate:1|skin:1|stomach:1|testis:1
APC Q1338 single residue *:17 2.62621150209083e-05 17 bowel:16|prostate:1
SMAD4 E330 single residue K:6|G:2|Q:2|*:1 2.64651886505787e-05 11 bowel:4|stomach:3|bladder:1|breast:1|lung:1|unk:1
TP53 T125 single residue M:16|R:6|K:3|P:3|A:2 2.69550487311592e-05 30 bowel:9|lung:6|brain:3|bladder:2|breast:2|head_neck:2|kidney:1|ovary:1|skin:1|stomach:1|thyroid:1|unk:1
PTEN G127 single residue E:5|R:5|V:3|*:1 3.07055801003565e-05 14 uterus:4|lung:3|brain:2|liver:1|skin:1|soft_tissue:1|stomach:1|testis:1
STK11 G242 single residue V:4|W:3|G:1|R:1 3.43165464187048e-05 9 lung:9
MYC S161 single residue L:11 3.61888337278651e-05 11 bowel:3|head_neck:3|skin:2|lung:1|ovary:1|uterus:1
KRAS L19 single residue F:12 3.71800769373073e-05 12 lung:3|bladder:2|bowel:2|biliary_tract:1|blood:1|lymph:1|stomach:1|unk:1
RB1 X654 single residue sp:8 3.72826658507451e-05 8 brain:2|lung:2|bladder:1|skin:1|soft_tissue:1|uterus:1
PIK3CA R115 single residue L:7|P:3|Q:1 3.87074236670905e-05 11 uterus:3|bowel:2|bladder:1|head_neck:1|lung:1|ovary:1|skin:1|thyroid:1
TP53 E294 single residue *:32 4.16264146157168e-05 32 lung:9|stomach:5|ovary:4|bowel:3|breast:3|head_neck:3|pancreas:3|bladder:2
PREX2 L50 single residue V:5|L:4 4.17095917701041e-05 9 stomach:7|bowel:2
HIST1H3C K37 single residue M:5|K:1 4.31460935771132e-05 6 head_neck:4|bladder:1|skin:1
RHOA Y34 single residue C:5|F:1 4.70657536214838e-05 6 stomach:4|bowel:2
SMARCA4 R1243 single residue W:9|G:1|L:1|P:1 4.81608011502394e-05 12 kidney:2|pancreas:2|biliary_tract:1|bone:1|brain:1|breast:1|lymph:1|ovary:1|stomach:1|uterus:1
RB1 X445 single residue sp:7 4.86028548096026e-05 7 lung:4|bladder:1|brain:1|liver:1
TP53 Q167 single residue *:19 4.9172615603644e-05 19 lung:3|stomach:3|bowel:2|breast:2|soft_tissue:2|uterus:2|biliary_tract:1|bladder:1|brain:1|head_neck:1|skin:1
RHOA L57 single residue V:6 5.06876440826244e-05 6 stomach:5|unk:1
PTEN X268 single residue sp:12 5.16990792357805e-05 12 brain:4|bowel:2|breast:2|lung:2|skin:1|uterus:1
VHL D121 single residue Y:6|G:2|V:1 5.25111408060234e-05 9 kidney:9
CDH1 X177 single residue sp:6 5.36416082793524e-05 6 stomach:5|bowel:1
FBXW7 D520 single residue N:6|Y:2|G:1|H:1|V:1 5.41988026669828e-05 11 bowel:5|bladder:3|lung:2|head_neck:1
RUNX1 R201 single residue *:4|Q:2|G:1 5.51149603976628e-05 7 blood:5|bowel:1|lung:1
VHL W88 single residue *:5|L:2|R:2 5.74074593167752e-05 9 kidney:9
PTEN G129 single residue E:4|R:3|G:2|V:2|*:1 5.95070750294617e-05 12 uterus:5|brain:2|lung:2|breast:1|prostate:1|soft_tissue:1
TP53 P250 single residue L:22|P:1|R:1 5.99198048007855e-05 24 lung:5|bowel:4|brain:4|stomach:3|ovary:2|biliary_tract:1|kidney:1|pancreas:1|skin:1|unk:1|uterus:1
CDKN2A L130 single residue Q:4|R:3|V:1 6.02822296383367e-05 8 pancreas:4|skin:3|stomach:1
CDKN2A Y129 single residue *:6|C:3 6.02822296383367e-05 9 lung:3|head_neck:2|pancreas:2|biliary_tract:1|stomach:1
CDH1 X440 single residue sp:7 6.09866366931617e-05 7 stomach:4|bladder:1|breast:1|skin:1
STK11 Q220 single residue *:9|P:1 6.68914447317085e-05 10 lung:7|adrenal_gland:1|stomach:1|thyroid:1
NOTCH2 R2400 single residue *:6 7.27895549355608e-05 6 lymph:4|brain:1|breast:1
EGFR H304 single residue Y:5 7.43524648342889e-05 5 brain:5
EGFR T363 single residue I:4|A:2|N:1 7.43524648342889e-05 7 brain:5|lung:1|lymph:1
TP53 E271 single residue K:27|*:14|Q:7|V:5 7.50411582407331e-05 53 bladder:18|lung:10|breast:4|head_neck:4|bowel:3|prostate:3|stomach:2|biliary_tract:1|brain:1|cervix:1|liver:1|ovary:1|pancreas:1|skin:1|thyroid:1|unk:1
VHL S68 single residue *:7|P:1 7.74714398748904e-05 8 kidney:8
RHOA E40 single residue Q:9|K:2|*:1|D:1|V:1 7.89360770697566e-05 14 head_neck:6|unk:3|lung:2|bladder:1|breast:1|stomach:1
VHL L158 single residue V:4|P:3|L:1|Q:1 8.08917220235343e-05 9 kidney:9
VHL P86 single residue S:4|L:2|T:2|R:1 8.08917220235343e-05 9 kidney:9
VHL V74 single residue D:5|G:1|V:1 8.08917220235343e-05 7 kidney:7
DICER1 D1810 single residue N:3|V:2|Y:2|A:1|H:1 8.22450136351905e-05 9 uterus:4|bowel:2|lung:1|skin:1|thyroid:1
PIK3CA N107 single residue S:3|I:2|N:1 8.25147220432943e-05 6 breast:2|prostate:2|lung:1|uterus:1
ASXL2 E330 single residue K:7|Q:2|D:1 9.4223821280924e-05 10 bladder:8|brain:1|breast:1
PAK7 M173 single residue I:12 9.55412663311122e-05 12 skin:11|unk:1
MAP2K2 F57 single residue L:4|V:2 9.70235389918942e-05 6 skin:2|breast:1|head_neck:1|pancreas:1|stomach:1
IRF4 K123 single residue R:3 9.97106212012724e-05 3 blood:3
PIM1 S97 single residue N:4|S:3|R:2|T:1 0.000100262103792936 10 lymph:9|blood:1
APC E1353 single residue *:15 0.000102562550865421 15 bowel:15
PBRM1 R710 single residue *:10|G:1 0.000109397947270069 11 biliary_tract:2|bowel:2|kidney:2|brain:1|penis:1|prostate:1|skin:1|uterus:1
RUNX1 R162 single residue G:2|K:1|S:1 0.000113108365223981 4 blood:4
B2M L12 single residue P:4|Q:2|L:1 0.000115092463101106 7 lymph:3|bowel:1|lung:1|stomach:1|unk:1
TP53 X32 single residue sp:20 0.000127539579249016 20 brain:4|head_neck:4|kidney:3|liver:2|lung:2|bladder:1|bowel:1|prostate:1|skin:1|testis:1
SUZ12 R101 single residue *:5|Q:1 0.000127918810761813 6 prostate:4|bowel:1|uterus:1
KEAP1 R260 single residue L:4|Q:4|*:2 0.000128688268304168 10 lung:4|kidney:2|liver:2|cervix:1|thyroid:1
MTOR C1483 single residue F:2|R:2|Y:2|W:1 0.000130995916923082 7 kidney:4|brain:1|breast:1|testis:1
EGFR P596 single residue L:4|S:2|P:1|R:1 0.000132911422078455 8 brain:6|bowel:1|skin:1
EIF1AX G15 single residue D:4|G:2|V:1 0.00013328049767376 7 brain:2|eye:2|bowel:1|lung:1|soft_tissue:1
MTOR V2006 single residue F:4|I:1|L:1|V:1 0.000143429913832681 7 kidney:3|brain:2|lymph:1|uterus:1
ERBB3 T355 single residue I:4|A:1|P:1 0.000144623354388927 6 breast:2|biliary_tract:1|bladder:1|bowel:1|stomach:1
NRAS G60 single residue G:5|E:1|V:1 0.00014613533141846 7 lung:3|skin:3|bowel:1
XPO1 R749 single residue Q:10|*:1 0.000146532020311594 11 bowel:4|uterus:4|breast:1|pancreas:1|unk:1
NOTCH1 F853 single residue C:2|I:2 0.00015082022409177 4 lung:4
EIF1AX R13 single residue H:4|L:4|C:2|G:1|P:1 0.000161841956275204 12 brain:3|uterus:3|bowel:1|eye:1|lung:1|prostate:1|skin:1|stomach:1
RB1 X127 single residue sp:7 0.000170187578635711 7 lung:4|brain:1|liver:1|unk:1
RB1 R579 single residue *:11 0.000170187578635711 11 skin:3|lung:2|unk:2|bladder:1|eye:1|head_neck:1|prostate:1
PIM1 G28 single residue D:6|A:1|V:1 0.000171510114503651 8 lymph:8
SF3B1 G740 single residue E:7|V:2 0.000175436453406427 9 lung:4|bladder:2|biliary_tract:1|blood:1|pancreas:1
SPOP F125 single residue L:3|C:1|I:1|V:1 0.00017822188506056 6 prostate:6
KDM6A X1336 single residue sp:6 0.000181209491771618 6 bladder:5|blood:1
ATRX R1426 single residue *:11|R:1 0.000182976033441754 12 brain:8|uterus:3|stomach:1
RB1 X203 single residue sp:9 0.000197456625104954 9 biliary_tract:1|bladder:1|liver:1|lung:1|skin:1|soft_tissue:1|stomach:1|unk:1|uterus:1
TP53 V172 single residue F:12|D:5|G:1 0.000199168992960357 18 lung:7|stomach:3|biliary_tract:1|bowel:1|brain:1|breast:1|head_neck:1|lymph:1|thyroid:1|unk:1
ERBB2 G776 single residue V:4|S:2 0.000214743024488163 6 stomach:3|bowel:2|bladder:1
CTCF H284 single residue Y:4|N:1|P:1 0.000216979970306031 6 breast:6
SMAD4 E526 single residue *:3|K:3|Q:2|A:1|D:1|V:1 0.000220507250911314 11 bowel:3|lung:3|biliary_tract:2|breast:1|pancreas:1|stomach:1
SMAD4 D355 single residue G:4|V:2|Y:1 0.000220507250911314 7 bowel:3|pancreas:2|prostate:1|stomach:1
ERCC2 S246 single residue Y:3|F:2|S:2 0.000220631227265414 7 bladder:6|soft_tissue:1
IRF4 C99 single residue R:4|C:2|Y:1 0.000227652714506587 7 lymph:4|head_neck:1|lung:1|pancreas:1
FGFR2 R203 single residue H:4|C:2 0.000229894911861478 6 bowel:6
STAT3 S614 single residue R:5 0.000238843518230703 5 lymph:4|stomach:1
CIC R201 single residue W:6|R:1 0.000256730145082327 7 brain:5|lymph:1|stomach:1
PDGFRA E229 single residue K:5|*:1|V:1 0.00025793882615122 7 brain:5|skin:2
FOXO1 S22 single residue P:3|W:3|S:1 0.000262158567401401 7 lymph:4|bowel:2|prostate:1
ERBB2 V659 single residue E:2|V:2|D:1 0.000268822656434572 5 lung:4|stomach:1
MAP2K1 C121 single residue S:5|C:1 0.000271001007196765 6 lung:2|biliary_tract:1|bladder:1|lymph:1|stomach:1
TP53 T155 single residue N:8|P:7|I:2|T:1 0.000276203605125193 18 lung:7|brain:5|breast:3|liver:1|pancreas:1|soft_tissue:1
PTPRD S431 single residue L:15|*:1|S:1 0.000280826354999932 17 uterus:5|skin:4|bowel:3|brain:1|lung:1|penis:1|prostate:1|stomach:1
CASP8 R127 single residue Q:8|*:5 0.000302848994448202 13 uterus:5|bladder:2|bowel:2|head_neck:2|breast:1|pancreas:1
RNF43 H86 single residue R:2|Y:2 0.000317636175436398 4 stomach:4
BRAF L485 single residue W:3|*:1|F:1|S:1 0.000333433570458539 6 bladder:2|skin:2|biliary_tract:1|lung:1
BCL2 A131 single residue D:7|T:2|V:1 0.000338355303555859 10 lymph:9|brain:1
STK11 X288 single residue sp:8 0.000339166875807386 8 lung:6|brain:1|stomach:1
CTNNB1 W383 single residue R:3|C:1|G:1|S:1 0.00034738723293938 6 bowel:3|liver:2|pancreas:1
PTEN A126 single residue S:4|D:3|V:3|G:1 0.000355422424396546 11 breast:4|stomach:2|uterus:2|brain:1|soft_tissue:1|unk:1
PTEN C105 single residue Y:2|*:1|G:1|R:1|S:1|W:1 0.000363990202363233 7 brain:3|skin:3|soft_tissue:1
TGFBR2 D471 single residue N:10|V:1|Y:1 0.000365084489940418 12 bowel:4|pancreas:3|lung:2|cervix:1|stomach:1|uterus:1
PTEN C124 single residue S:4|Y:2|G:1|R:1 0.000369460106003662 8 breast:4|bowel:1|prostate:1|thyroid:1|uterus:1
PTPRT L668 single residue V:3|L:2 0.000383122377927383 5 stomach:5
RAC1 N111 single residue K:3|I:1|S:1 0.000384600240645875 5 blood:1|bowel:1|skin:1|soft_tissue:1|thyroid:1
GATA2 C352 single residue *:1|C:1|F:1|R:1 0.000386130527618172 4 lung:4
MAP2K1 Y130 single residue C:3|H:1|N:1 0.000390930809868608 5 lymph:2|bowel:1|liver:1|lung:1
TP53 W53 single residue *:22 0.000393305860576817 22 lung:4|pancreas:4|skin:3|biliary_tract:2|bowel:2|ovary:2|bladder:1|brain:1|breast:1|soft_tissue:1|stomach:1
TP53 Q331 single residue *:39|H:8 0.000393305860576817 47 lung:12|bladder:9|breast:6|head_neck:5|skin:4|bowel:3|ovary:2|biliary_tract:1|brain:1|pancreas:1|stomach:1|thyroid:1|uterus:1
NFE2L2 D77 single residue G:3|H:2|V:1|Y:1 0.000440112681913558 7 liver:2|lung:2|cervix:1|kidney:1|skin:1
EGFR T263 single residue P:3|I:1 0.000443937077361959 4 brain:4
MTOR M2327 single residue I:5|V:1 0.000446236341703313 6 kidney:2|bladder:1|bowel:1|brain:1|uterus:1
DNMT1 E51 single residue K:5 0.000457369167019088 5 uterus:5
SETD2 Y1666 single residue C:4|*:1|H:1 0.000460067179768372 6 kidney:2|lung:2|bone:1|pancreas:1
RHOA G62 single residue E:3|R:3|V:1 0.000460203695335467 7 stomach:4|bowel:1|breast:1|head_neck:1
RB1 X46 single residue sp:7 0.000467623736978692 7 lung:4|bladder:1|prostate:1|uterus:1
BRAF G596 single residue R:4|C:1|D:1|S:1|V:1 0.000495016870209048 8 lung:5|bladder:1|blood:1|brain:1
EP300 C1164 single residue Y:5|S:1 0.000497503425615413 6 bladder:3|head_neck:2|bone:1
PTEN R335 single residue *:12|G:1|P:1 0.000501373788906304 14 brain:4|uterus:3|bowel:2|head_neck:2|bladder:1|lymph:1|unk:1
FGFR2 Y375 single residue C:5 0.000502673004420345 5 uterus:2|biliary_tract:1|bowel:1|cervix:1
MST1 G673 single residue S:6 0.000504582989691505 6 lymph:2|breast:1|head_neck:1|lung:1|ovary:1
MAP2K1 T386 single residue T:3 0.000512968367623452 3 bladder:3
MAP3K1 S1330 single residue L:8|W:2 0.000515913573968169 10 bowel:2|breast:2|stomach:2|brain:1|ovary:1|unk:1|uterus:1
FOXA1 S250 single residue F:5|Y:1 0.000517133957868793 6 breast:6
SMAD4 W524 single residue C:6|L:1|R:1|S:1 0.000523513784646524 9 pancreas:3|bowel:2|stomach:2|breast:1|lung:1
TP53 L257 single residue Q:7|P:4|R:4|L:1|V:1 0.000534067822950071 17 bowel:6|prostate:3|bladder:2|breast:1|liver:1|ovary:1|pancreas:1|unk:1|uterus:1
STK11 X97 single residue sp:8 0.000549663500781769 8 lung:6|stomach:1|unk:1
VHL R161 single residue *:7|Q:2|L:1 0.000554684648130705 10 kidney:7|adrenal_gland:1|breast:1|stomach:1
KEAP1 R470 single residue C:7|H:2|S:1 0.000575237923548754 10 lung:7|head_neck:2|skin:1
ARAF P216 single residue L:3|R:1 0.000593515828701691 4 biliary_tract:3|soft_tissue:1
GNAQ R183 single residue Q:6|*:4 0.000622969148509286 10 eye:4|bowel:3|pancreas:1|penis:1|skin:1
RB1 X702 single residue sp:6 0.000627863387091009 6 bladder:2|eye:1|head_neck:1|lung:1|soft_tissue:1
EP300 H1451 single residue H:1|L:1|P:1|Q:1|R:1 0.000628378364028597 5 bladder:1|brain:1|breast:1|lung:1|uterus:1
PTEN G165 single residue E:6|R:5|*:1 0.000639515145732353 12 brain:3|uterus:3|lung:2|blood:1|bowel:1|kidney:1|skin:1
PTEN X85 single residue sp:8 0.000639515145732353 8 brain:3|prostate:2|cervix:1|unk:1|uterus:1
RHOA T37 single residue I:4|A:1|S:1 0.00065068897287312 6 bowel:3|head_neck:1|lymph:1|thyroid:1
SMAD4 C363 single residue F:2|R:2|S:1|Y:1 0.00065164187004951 6 stomach:2|bladder:1|bowel:1|breast:1|lung:1
RAC1 G12 single residue R:3|V:3 0.000661400410008793 6 testis:4|unk:2
ARID1A R1722 single residue *:10 0.000675573097921338 10 uterus:4|bowel:3|biliary_tract:1|lung:1|stomach:1
FOXO1 S205 single residue N:2|S:2|Y:1 0.00070080979931149 5 lymph:4|bowel:1
KRAS A11 single residue A:6|T:2 0.000725138589585693 8 lung:4|pancreas:3|vulva:1
APC E1408 single residue *:13 0.000733406551801644 13 bowel:13
GSK3B X239 single residue sp:3 0.000748704539069988 3 kidney:3
RB1 X605 single residue sp:7 0.000771125042778052 7 bladder:2|lung:2|brain:1|breast:1|prostate:1
CIC S231 single residue N:2|G:1|I:1 0.000799845943361296 4 brain:4
FAT1 R1627 single residue *:7|Q:5 0.000802593850312719 12 uterus:4|head_neck:3|bowel:2|pancreas:1|skin:1|stomach:1
SOCS1 A3 single residue T:3|E:1|P:1|R:1 0.000842046934360504 6 lymph:6
AKT1 Q79 single residue K:6 0.000879321560858086 6 breast:2|prostate:2|uterus:2
FBXW7 R278 single residue *:10 0.000882677384534049 10 bowel:6|stomach:2|bladder:1|brain:1
PTEN Q171 single residue *:13|R:2|K:1 0.000888705070997375 16 breast:3|lung:3|head_neck:2|stomach:2|bladder:1|brain:1|cervix:1|liver:1|prostate:1|uterus:1
VHL I151 single residue N:2|T:2|F:1|S:1 0.000898333934521553 6 kidney:6
U2AF1 I24 single residue T:4|V:1 0.000965907644734733 5 adrenal_gland:1|pancreas:1|stomach:1|unk:1|uterus:1
BCL2 K22 single residue K:8|*:1|R:1 0.0009664695729283 10 lymph:9|head_neck:1
PIK3CA M1004 single residue I:8|V:1 0.000967541604830105 9 breast:3|uterus:2|bladder:1|bowel:1|head_neck:1|lung:1
ASXL2 M1 single residue T:5|I:1 0.000968286986342165 6 bowel:3|stomach:2|skin:1
ALK F1245 single residue I:2|V:1 0.000975062354863964 3 brain:3
PTEN Y155 single residue C:4|H:1 0.00100344772445177 5 uterus:4|biliary_tract:1
HNF1A G288 single residue G:3 0.00100775596981065 3 lymph:3
FBXW7 R224 single residue *:5|Q:5 0.00102350502188112 10 bowel:3|uterus:3|cervix:1|lung:1|penis:1|thyroid:1
TP53 N131 single residue I:8|S:3|K:1|N:1 0.00103631572883874 13 lung:6|pancreas:2|bowel:1|brain:1|liver:1|prostate:1|skin:1
TP53 L265 single residue P:8|L:6|R:4|M:1 0.00103631572883874 19 brain:3|head_neck:3|bowel:2|breast:2|pancreas:2|prostate:2|unk:2|bladder:1|lung:1|ovary:1
CUL3 M299 single residue R:4|V:1 0.00104496519960921 5 prostate:3|brain:1|stomach:1
TP53 Q192 single residue *:43|H:1|L:1 0.00106690268651275 45 bladder:8|lung:8|breast:5|head_neck:5|ovary:5|pancreas:3|bowel:2|stomach:2|thyroid:2|biliary_tract:1|liver:1|skin:1|unk:1|uterus:1
CHEK2 R346 single residue C:3|G:2|S:2|H:1 0.00106946994093738 8 lung:3|bowel:1|breast:1|head_neck:1|ovary:1|soft_tissue:1
PIK3CA E39 single residue K:5|G:1 0.00110112193556633 6 uterus:4|brain:1|breast:1
STK11 H174 single residue H:2|D:1|L:1|R:1|Y:1 0.00114520467593057 6 kidney:3|lung:3
EGFR A750 single residue A:2|P:2 0.00114853660633903 4 lung:4
FBXW7 T532 single residue P:2|I:1 0.00116715416078893 3 bladder:3
CREBBP D1435 single residue G:3|H:2|N:2|Y:2 0.00117499563003119 9 bladder:4|lung:3|lymph:1|ovary:1
SRSF2 P95 single residue L:3|H:2|R:1 0.00121973194958252 6 blood:3|lymph:1|skin:1|stomach:1
VHL C162 single residue Y:3|R:2|*:1|F:1|W:1 0.00122944432376974 8 kidney:7|pancreas:1
CARD11 K215 single residue T:3|M:1|N:1 0.0013161682155681 5 lymph:4|uterus:1
DIS3 R780 single residue K:2|T:2|G:1|S:1 0.00133003215812735 6 blood:4|kidney:1|thyroid:1
PDPK1 P499 single residue S:3|L:2 0.00133636572478297 5 skin:5
ARID1A R1461 single residue *:9|Q:1 0.00133954357898348 10 stomach:3|bowel:2|head_neck:1|lymph:1|prostate:1|skin:1|uterus:1
PIK3CA C604 single residue R:5 0.00134821997922493 5 uterus:2|bowel:1|head_neck:1|pancreas:1
FOXA1 Y259 single residue C:2|S:2|F:1 0.00135085457803862 5 breast:2|prostate:2|skin:1
TP53 E198 single residue *:26 0.00141363825086011 26 lung:8|stomach:5|bowel:3|breast:3|ovary:2|bladder:1|liver:1|pancreas:1|prostate:1|uterus:1
PTEN X342 single residue sp:8 0.00142850248666773 8 brain:5|skin:2|uterus:1
STK11 N181 single residue I:1|S:1|T:1|Y:1 0.001605169956216 4 lung:4
PTEN M35 single residue I:4|V:3|L:1 0.00168869830239239 8 brain:3|bowel:2|biliary_tract:1|kidney:1|lung:1
MYC T73 single residue I:3|P:2|A:1 0.00170415109295424 6 lymph:3|brain:1|lung:1|stomach:1
CDH1 D288 single residue V:4|N:1 0.0017736054696059 5 stomach:4|breast:1
DNMT3B V229 single residue M:3|V:3|L:1 0.00184129930922227 7 lung:4|breast:2|uterus:1
ERCC2 Y14 single residue C:3 0.00185831947498718 3 bladder:3
FOXP1 R514 single residue H:6|C:3 0.00189103885682882 9 bowel:4|bladder:3|breast:1|soft_tissue:1
KRAS Q22 single residue K:5|H:1 0.0019130164353186 6 bowel:3|blood:1|lung:1|lymph:1
RICTOR S1101 single residue L:9|S:1 0.00198059525742831 10 skin:4|uterus:2|brain:1|ovary:1|penis:1|unk:1
PTPRT L695 single residue F:6|L:2|R:1 0.0020269285120102 9 skin:8|bowel:1
TP53 G262 single residue V:17 0.00203376888510967 17 uterus:4|ovary:3|breast:2|lung:2|bowel:1|head_neck:1|lymph:1|prostate:1|skin:1|stomach:1
EIF1AX G6 single residue D:4|C:1|R:1|S:1 0.00204928105723417 7 eye:2|lung:2|soft_tissue:1|thymus:1|unk:1
PTEN S170 single residue N:6|G:1|I:1 0.00205793039150722 8 brain:4|kidney:1|lung:1|ovary:1|uterus:1
FOXA1 S242 single residue C:3|F:1|Y:1 0.00206253182693294 5 breast:5
DNAJB1 L190 single residue L:4 0.00208705078434093 4 brain:1|head_neck:1|lymph:1|prostate:1
TP53 F113 single residue C:6|V:6|S:2|F:1|L:1|P:1 0.00211656002293528 17 breast:7|bowel:2|stomach:2|brain:1|liver:1|lung:1|lymph:1|prostate:1|skin:1
RAD50 D69 single residue Y:4|N:2 0.00212729720788355 6 lung:4|bladder:1|bowel:1
GNAS R160 single residue C:7|H:1|P:1 0.00218412256499689 9 bowel:2|stomach:2|breast:1|lung:1|pancreas:1|prostate:1|uterus:1
FGFR4 N535 single residue K:3 0.00224497777269147 3 breast:3
PPP6C S270 single residue L:7 0.00226807160027759 7 skin:6|head_neck:1
PIK3CA P471 single residue L:5|A:2 0.0022910753942165 7 bladder:1|bowel:1|brain:1|breast:1|liver:1|skin:1|uterus:1
CREBBP Y1450 single residue D:2|N:2|C:1 0.00236925569277985 5 head_neck:2|lymph:2|lung:1
RB1 X89 single residue sp:8 0.00238216671696255 8 lung:7|brain:1
KMT2D L1375 single residue L:2|I:1 0.00240632662871761 3 kidney:3
ERCC2 P463 single residue L:4|Q:1|S:1 0.00240750708339393 6 bladder:4|kidney:1|liver:1
APC E1379 single residue *:11 0.00245822451409422 11 bowel:11
CYSLTR2 L129 single residue Q:3 0.00248880623374966 3 eye:3
IL7R I241 single residue V:2|F:1|L:1|M:1 0.00254942980031351 5 lung:5
SMARCA4 R1135 single residue W:5|Q:4 0.00257748951777747 9 bladder:3|brain:2|stomach:2|head_neck:1|lymph:1
KEAP1 G480 single residue W:7|G:1|V:1 0.00262221927300804 9 lung:8|skin:1
VHL G114 single residue A:4|R:2|C:1 0.00271531464293943 7 kidney:7
KMT2D R1903 single residue *:4|R:1 0.00273839857417312 5 bladder:4|bowel:1
MAP3K1 L380 single residue S:3 0.00275840785948893 3 breast:3
PDGFRA N659 single residue K:4|S:1|Y:1 0.00278269713630747 6 brain:4|soft_tissue:2
ERCC2 D609 single residue E:2|G:1 0.00281270456279724 3 bladder:3
ERCC2 E606 single residue Q:4|G:2 0.00281270456279724 6 bladder:5|prostate:1
BCL10 L174 single residue *:3 0.00283328439617831 3 lymph:3
PIK3CA D939 single residue G:4 0.00289242577603165 4 breast:2|uterus:2
MAP2K1 Q56 single residue P:5 0.00292307151816356 5 bowel:2|lung:2|uterus:1
CDH1 X722 single residue sp:4 0.00296596686937428 4 breast:4
CDH1 R335 single residue *:6|Q:1 0.00296596686937428 7 breast:5|bowel:1|stomach:1
CIC N205 single residue S:3 0.00300209188506545 3 brain:3
KDM6A X1293 single residue sp:5 0.00305903400488818 5 bladder:2|lung:1|skin:1|stomach:1
SOX17 A96 single residue G:4 0.0031058778949461 4 uterus:3|cervix:1
SMAD4 L536 single residue P:2|Q:1|R:1 0.00311073967452292 4 bowel:2|pancreas:2
PIK3CA T1052 single residue K:5 0.00312237313750376 5 bowel:2|stomach:2|liver:1
PTEN Y178 single residue *:3|C:1|H:1 0.00335970330625585 5 brain:2|skin:2|lung:1
KEAP1 M110 single residue I:3|V:3 0.00338070344003822 6 lung:6
KEAP1 R272 single residue C:3|H:2|P:2|L:1 0.00338070344003822 8 lung:7|head_neck:1
NF1 R1241 single residue *:7 0.00343576164649043 7 skin:6|uterus:1
GATA3 R364 single residue S:2|T:2|G:1 0.00354740691184041 5 breast:5
JUN E112 single residue K:5|Q:2 0.00366249429213643 7 bladder:4|lung:2|breast:1
CTCF S354 single residue F:9|Y:1 0.00367325788101451 10 bladder:3|skin:3|biliary_tract:1|blood:1|head_neck:1|uterus:1
RB1 R455 single residue *:9 0.00379431585215353 9 uterus:2|bladder:1|brain:1|breast:1|prostate:1|skin:1|soft_tissue:1|unk:1
ALK R401 single residue *:9|L:1|Q:1 0.0038099485803712 11 bowel:6|bladder:1|head_neck:1|lung:1|skin:1|uterus:1
ARID2 R314 single residue C:8|S:1 0.00383083238325229 9 skin:6|bowel:1|pancreas:1|unk:1
MED12 V1223 single residue L:2|V:1 0.00387330885595878 3 prostate:3
KLF4 K409 single residue Q:5|N:2 0.0040215756215764 7 breast:2|pancreas:2|bladder:1|brain:1|prostate:1
STK11 E165 single residue *:6|Q:2|K:1 0.00404178594646078 9 lung:6|breast:2|unk:1
AKT3 E17 single residue K:9|*:1 0.00407836413892336 10 skin:3|soft_tissue:2|bladder:1|brain:1|kidney:1|penis:1|prostate:1
CARD11 L251 single residue P:3 0.00409188109411549 3 lymph:3
STK11 P221 single residue L:6|P:1|S:1 0.00419615615814037 8 lung:2|bladder:1|bowel:1|breast:1|kidney:1|stomach:1|unk:1
TP53 L111 single residue P:7|R:6|Q:4|M:1 0.00420150034956331 18 breast:3|liver:3|brain:2|lung:2|stomach:2|adrenal_gland:1|bladder:1|blood:1|bowel:1|prostate:1|skin:1
TP53 Q104 single residue *:22|H:1 0.00440344845895086 23 lung:9|bowel:3|stomach:3|skin:2|biliary_tract:1|head_neck:1|ovary:1|pancreas:1|soft_tissue:1|uterus:1
SESN2 I425 single residue V:2 0.00451586263584824 2 bladder:2
MAP2K4 S184 single residue L:7|S:1|W:1 0.00461638383133961 9 breast:6|brain:1|head_neck:1|stomach:1
SMARCA4 R973 single residue Q:5|W:5 0.00471444398662183 10 lymph:3|bowel:2|stomach:2|cervix:1|thymus:1|uterus:1
ERBB2 G660 single residue D:3|G:1|R:1 0.00493020193582609 5 bladder:3|cervix:1|uterus:1
NCOA3 R80 single residue C:2|H:1 0.00503087688152371 3 bladder:3
FOXA1 D226 single residue N:5|G:4 0.00504815371636297 9 breast:5|prostate:3|bladder:1
FOXP1 X511 single residue sp:11 0.00505681355917067 11 breast:5|bladder:4|lung:2
PIK3R1 K379 single residue E:2|N:2 0.0051280355068743 4 brain:3|soft_tissue:1
ERBB2 R103 single residue Q:6 0.00522897959822954 6 bladder:5|pancreas:1
PIM1 K24 single residue N:4|K:3 0.00528607615357521 7 lymph:7
PTEN D24 single residue G:3|E:2|H:2|V:2|N:1 0.00530937503240004 10 breast:2|kidney:2|stomach:2|uterus:2|soft_tissue:1|thyroid:1
KRAS D33 single residue E:4 0.00545510994623059 4 bowel:2|lung:1|testis:1
PTEN Y336 single residue *:7 0.0055022798880087 7 brain:2|uterus:2|breast:1|head_neck:1|prostate:1
PTEN P38 single residue S:7|L:3|F:1 0.00565128852492496 11 skin:9|kidney:1|uterus:1
AXL A273 single residue V:3|P:1 0.0057559976089476 4 bladder:3|bowel:1
KDR R1032 single residue Q:8|*:4 0.00584924439117527 12 skin:5|bowel:3|brain:1|prostate:1|unk:1|uterus:1
KDR S1037 single residue S:6|L:4|T:1 0.00584924439117527 11 skin:4|bowel:2|brain:1|lung:1|pancreas:1|stomach:1|thyroid:1
TP53 D259 single residue Y:19|V:7|H:2|N:2|D:1 0.00592807649110612 31 bladder:5|bowel:5|lung:5|ovary:4|pancreas:3|biliary_tract:2|head_neck:2|adrenal_gland:1|kidney:1|liver:1|skin:1|soft_tissue:1
GNA11 R183 single residue C:5|H:1|R:1 0.00595910002721709 7 skin:2|adrenal_gland:1|breast:1|eye:1|lung:1|prostate:1
CDKN2A P48 single residue L:10|R:2 0.00610553972408702 12 skin:6|pancreas:2|brain:1|head_neck:1|soft_tissue:1|stomach:1
RB1 X776 single residue sp:6 0.00618941093976789 6 lung:2|bladder:1|bowel:1|pancreas:1|prostate:1
DIS3 D479 single residue Y:2|G:1|H:1|V:1 0.00626223765902431 5 lung:4|breast:1
KMT2D R2685 single residue *:7|R:1 0.00628779581431989 8 bladder:3|bowel:1|brain:1|cervix:1|lung:1|skin:1
RB1 R467 single residue *:9 0.00629917353625844 9 uterus:2|bladder:1|bowel:1|brain:1|breast:1|prostate:1|skin:1|stomach:1
PIK3CA H1065 single residue Y:4|L:1 0.00632321990539015 5 bladder:1|bowel:1|breast:1|kidney:1|lung:1
PIK3R1 D560 single residue G:3|H:2|Y:2|N:1 0.00650808905211078 8 brain:3|bowel:1|breast:1|head_neck:1|lung:1|lymph:1
MGA R1242 single residue *:9 0.00652467442006238 9 skin:3|bladder:2|uterus:2|bowel:1|breast:1
TP63 E609 single residue K:11 0.00654115661493069 11 skin:9|unk:1|uterus:1
TP53 I251 single residue F:5|N:5|S:3|I:1|M:1 0.00655470239847348 15 head_neck:3|ovary:3|pancreas:2|bowel:1|breast:1|lung:1|prostate:1|skin:1|soft_tissue:1|stomach:1
PIK3CA G364 single residue R:5|A:1 0.00666202370596311 6 bowel:2|bladder:1|breast:1|lung:1|uterus:1
CDKN2A N42 single residue H:2|I:1|K:1|Y:1 0.00666274404041663 5 head_neck:1|lung:1|pancreas:1|stomach:1|unk:1
DIS3 R689 single residue Q:8|G:1 0.00674087265617022 9 bowel:5|blood:1|breast:1|prostate:1|uterus:1
DIS3 L767 single residue F:4 0.00674087265617022 4 bladder:1|brain:1|liver:1|lung:1
DIS3 R382 single residue Q:8|G:1 0.00674087265617022 9 bowel:3|uterus:2|bladder:1|prostate:1|stomach:1|thyroid:1
HIST1H3B E51 single residue K:4|E:3|Q:3|D:2 0.00676671353335492 12 lung:3|bladder:2|breast:2|skin:2|ovary:1|stomach:1|unk:1
PTEN Y16 single residue *:3|D:1|Y:1 0.00677821009113384 5 uterus:2|bowel:1|brain:1|lung:1
GLI1 R380 single residue Q:6|*:1|R:1 0.0067835673540912 8 bowel:5|lung:2|uterus:1
ATM L2890 single residue P:2|I:1|R:1|V:1 0.0068729555794163 5 bladder:1|lung:1|skin:1|stomach:1|unk:1
JAK1 L910 single residue L:1|P:1|S:1 0.00697986479202836 3 liver:3
EGFR L838 single residue M:2|P:1 0.00715263397573601 3 kidney:3
RAC1 Q61 single residue K:2|R:2 0.00720141225078055 4 unk:2|prostate:1|testis:1
EIF1AX P2 single residue L:4|S:2|P:1 0.0072542682644841 7 unk:2|eye:1|lung:1|skin:1|soft_tissue:1|uterus:1
CASP8 R491 single residue *:9|Q:1 0.00730591712309491 10 bowel:3|head_neck:3|bladder:1|cervix:1|pancreas:1|skin:1
VHL H115 single residue N:4|Y:2|Q:1 0.00743191624202421 7 kidney:7
MAP2K4 X297 single residue sp:6 0.00744286485556026 6 breast:3|lung:1|stomach:1|thyroid:1
MAP2K4 R134 single residue W:9|L:1|Q:1 0.00744286485556026 11 bowel:4|breast:3|pancreas:2|lung:1|prostate:1
BCL6 R618 single residue C:6|H:1 0.00748624177672911 7 skin:3|bowel:2|breast:1|lung:1
ERBB2 D277 single residue Y:4|H:2|G:1|V:1 0.00753448990574709 8 bladder:6|bowel:1|lung:1
PTEN Y346 single residue *:2|D:2|C:1|H:1 0.00758644893706279 6 brain:2|bowel:1|breast:1|kidney:1|lung:1
PTEN Y177 single residue *:2|C:1|D:1|F:1 0.00758644893706279 5 skin:2|bladder:1|brain:1|thyroid:1
B2M L7 single residue *:3|S:2 0.00770415024339667 5 lymph:3|skin:2
FBXW7 E287 single residue D:2|Q:2|V:2|K:1 0.00774127307000243 7 bowel:2|lung:2|stomach:2|ovary:1
STK11 K84 single residue *:4 0.00790318256508381 4 breast:1|lung:1|pancreas:1|thyroid:1
FOXL2 E118 single residue K:6|Q:1 0.00808298632412623 7 bladder:2|lung:2|breast:1|cervix:1|skin:1
APC R213 single residue *:51 0.00809179351097399 51 bowel:50|thyroid:1
APC Q1303 single residue *:10 0.00828700389539349 10 bowel:10
APC Q1294 single residue *:7 0.00828700389539349 7 bowel:7
APC Q1328 single residue *:8 0.00828700389539349 8 bowel:7|uterus:1
EGFR K754 single residue E:1|I:1|K:1 0.00841607903718246 3 lung:3
TP63 S365 single residue L:7|S:3|*:2 0.00847835763366027 12 skin:5|bowel:1|brain:1|kidney:1|lung:1|pancreas:1|prostate:1|testis:1
EPHB1 R743 single residue W:4|Q:3|R:2 0.00851534342722432 9 skin:6|brain:1|prostate:1|stomach:1
PTPN11 N308 single residue D:2|S:1 0.00866741098637617 3 brain:3
PTPN11 F285 single residue S:3|V:1 0.00866741098637617 4 brain:3|blood:1
PIK3CA C90 single residue G:1|R:1|S:1|Y:1 0.00868121273346674 4 brain:2|bladder:1|cervix:1
SF3B1 D894 single residue G:2|N:2|A:1|Y:1 0.00868422598732493 6 blood:3|skin:2|kidney:1
RB1 R787 single residue *:9|Q:2 0.00888303132578564 11 uterus:3|skin:2|bladder:1|bowel:1|cervix:1|ovary:1|prostate:1|soft_tissue:1
SDHA V644 single residue M:6|L:1 0.00891411211670894 7 lymph:3|lung:2|brain:1|head_neck:1
PIM1 Q37 single residue H:3|Q:2 0.00912235538516294 5 lymph:5
CIC W238 single residue *:2|R:1 0.00939318796151452 3 brain:3
RIT1 M90 single residue I:11 0.00949362579637069 11 bladder:4|lung:3|biliary_tract:1|blood:1|breast:1|cervix:1
ERBB2 T862 single residue A:4 0.00960995949933103 4 bladder:2|breast:1|stomach:1
SMAD4 D493 single residue N:3|G:2|A:1|H:1 0.00966195161579594 7 lung:3|bowel:2|biliary_tract:1|prostate:1
MTOR A1971 single residue T:4|P:1|S:1 0.00966713792920051 6 bladder:1|blood:1|brain:1|kidney:1|liver:1|prostate:1
HLA-B E69 single residue A:3|K:2 0.00998841609209048 5 lymph:4|bowel:1
PTEN W111 single residue *:6|G:1|R:1|S:1 0.0100439635759994 9 lung:2|bowel:1|brain:1|lymph:1|prostate:1|skin:1|thyroid:1|uterus:1
PTEN C71 single residue Y:5|*:1|F:1 0.0100439635759994 7 brain:5|kidney:1|uterus:1
TNFRSF14 M1 single residue I:2|K:1|T:1 0.0100655869328098 4 lymph:4
RB1 R445 single residue *:10 0.0101372969926842 10 brain:3|lung:2|soft_tissue:2|biliary_tract:1|bladder:1|stomach:1
HIST1H3B E106 single residue K:8|Q:5|E:1 0.0101928202808917 14 lung:6|skin:4|bladder:1|breast:1|head_neck:1|prostate:1
EGFR L833 single residue F:2|V:2|M:1 0.0101972498092972 5 lung:4|breast:1
FOXO1 T24 single residue I:2|M:1 0.0102244267593044 3 lymph:3
CDKN2A S12 single residue *:8|L:4 0.0102315474126578 12 bladder:4|lung:3|breast:2|skin:1|thymus:1|unk:1
EP300 X1539 single residue sp:5 0.0102558590758561 5 stomach:2|bladder:1|bowel:1|lung:1
CREBBP W1502 single residue C:3|*:1|L:1|R:1 0.0102805884281454 6 lymph:3|bladder:2|lung:1
ERBB3 F219 single residue L:4|C:1 0.0103410425708807 5 bladder:1|cervix:1|head_neck:1|stomach:1|uterus:1
HLA-A L180 single residue L:7 0.0104831562927601 7 bowel:5|lymph:2
CTNNB1 K292 single residue E:3|T:1 0.0105287083300164 4 biliary_tract:1|bowel:1|lung:1|skin:1
FOXP1 S448 single residue L:8|S:2 0.0106173709484405 10 skin:5|bowel:4|uterus:1
MTOR L1460 single residue P:4 0.0109744673866623 4 kidney:3|thyroid:1
RNF43 R371 single residue *:9 0.0109768899642112 9 pancreas:5|bowel:2|biliary_tract:1|stomach:1
KDM6A G526 single residue *:1|E:1|G:1|V:1 0.0113277605529172 4 kidney:3|head_neck:1
ATM R1466 single residue *:4|Q:3|P:2 0.0114010066702172 9 bladder:3|bowel:3|blood:1|lung:1|stomach:1
CARD11 D357 single residue V:3|N:1 0.0114332958492849 4 lymph:3|lung:1
PRDM14 F204 single residue F:5|V:1 0.011513819119626 6 skin:5|stomach:1
IGF1R G129 single residue A:1|G:1|R:1 0.011524838515816 3 breast:3
ERBB4 K1002 single residue T:5|R:1 0.0116020936023758 6 stomach:5|bowel:1
ERBB4 K1223 single residue T:3|R:2|M:1 0.0116020936023758 6 stomach:5|bowel:1
SMO W535 single residue L:3 0.0116503765899911 3 brain:3
GPS2 X242 single residue sp:2 0.0118955414082871 2 liver:2
NSD1 F392 single residue F:7 0.0119254817879873 7 bowel:5|uterus:2
RARA F286 single residue S:2|C:1|I:1 0.0121887973685868 4 lung:2|breast:1|skin:1
FBXW7 R14 single residue Q:6|*:3 0.0122075449025547 9 bowel:4|bladder:2|uterus:2|stomach:1
FBXW7 G437 single residue V:3|*:1|E:1|G:1 0.0122075449025547 6 bladder:1|blood:1|bowel:1|lung:1|stomach:1|uterus:1
TP53 D208 single residue V:7|G:2|N:2|E:1 0.0123251218508829 12 breast:4|lung:3|brain:2|bladder:1|ovary:1|uterus:1
PIK3CA P539 single residue R:6 0.0127676568720805 6 breast:2|lung:2|pancreas:1|unk:1
DICER1 D1709 single residue N:10 0.0129764974536984 10 uterus:4|bladder:1|bowel:1|brain:1|lung:1|skin:1|soft_tissue:1
CRLF2 S128 single residue L:4|S:3 0.0130680865115582 7 skin:3|lung:2|bowel:1|breast:1
RIT1 F82 single residue L:3|C:1 0.0131232804958808 4 lung:2|bowel:1|skin:1
MYD88 M232 single residue T:3 0.0134687878326664 3 blood:2|lymph:1
PIK3R1 Y452 single residue C:2|H:1|N:1 0.0137524642529949 4 uterus:2|head_neck:1|stomach:1
KEAP1 G333 single residue C:4|S:2|F:1 0.0137807717512058 7 lung:7
BCL2 G33 single residue R:5|G:1 0.0137911686286346 6 lymph:6
RBM10 R153 single residue *:7|G:1 0.014058743321404 8 bladder:2|lung:2|bowel:1|breast:1|head_neck:1|pancreas:1
GATA3 R366 single residue *:4|Q:1 0.0141725794141758 5 breast:4|unk:1
TP53 N247 single residue I:8|N:7 0.0141746189488235 15 skin:7|lung:3|soft_tissue:2|breast:1|ovary:1|stomach:1
TP53 R181 single residue C:9|H:9|P:8 0.0141746189488235 26 lung:7|bowel:3|brain:3|skin:3|bladder:2|prostate:2|stomach:2|ovary:1|pancreas:1|soft_tissue:1|uterus:1
RHOA L22 single residue R:3|L:1|P:1 0.0143875675561847 5 stomach:3|bladder:1|pancreas:1
STK11 P179 single residue L:3|Q:2|R:2 0.0144151536030241 7 lung:3|adrenal_gland:1|cervix:1|pancreas:1|skin:1
ATRX X199 single residue sp:4 0.0145598381914334 4 brain:3|uterus:1
PTEN L140 single residue *:3|F:1 0.0146528812265087 4 uterus:2|breast:1|soft_tissue:1
STAT3 F384 single residue L:2|V:1|Y:1 0.014884260303677 4 uterus:2|breast:1|prostate:1
TP53 Y107 single residue *:8|D:6|Y:1 0.014979632693567 15 breast:5|bowel:2|lung:2|liver:1|lymph:1|prostate:1|skin:1|stomach:1|uterus:1
STAT3 D661 single residue V:3|Y:2 0.0151718798921814 5 head_neck:2|blood:1|lymph:1|stomach:1
KNSTRN P28 single residue L:3|S:2 0.0151833562317312 5 skin:5
PIK3R1 X475 single residue sp:5 0.0153614035834394 5 stomach:2|brain:1|prostate:1|skin:1
EIF1AX K10 single residue E:3|T:1 0.0159902632702165 4 bowel:2|brain:1|skin:1
ERBB3 M60 single residue K:3|R:1 0.0162084155769783 4 bladder:1|bowel:1|stomach:1|uterus:1
TGFBR2 E544 single residue K:5 0.016266709218872 5 head_neck:5
KMT2D R5432 single residue W:4|Q:3|R:1 0.0163159021207786 8 skin:3|lung:2|bowel:1|brain:1|head_neck:1
KEAP1 G417 single residue V:4|E:1|R:1|W:1 0.0163931870611199 7 lung:7
PTEN L146 single residue *:4 0.0164604834364009 4 uterus:2|lung:1|stomach:1
MYC V7 single residue M:4 0.0166440841859353 4 lymph:4
CREBBP L1499 single residue P:2|Q:1|R:1 0.0171122100701789 4 lymph:3|bowel:1
TRAF7 N520 single residue S:3|Y:1 0.0171380664656178 4 peritoneum:2|bowel:1|soft_tissue:1
CARD11 D401 single residue N:3 0.017237006488171 3 lymph:3
ASXL2 R357 single residue *:9 0.0174219164329083 9 skin:3|bowel:2|bladder:1|breast:1|prostate:1|unk:1
TP53 K120 single residue E:5|N:2|*:1|M:1 0.0176054406780031 9 brain:4|lung:2|head_neck:1|skin:1|stomach:1
MYD88 P166 single residue L:3|P:1 0.0177532694963659 4 skin:4
PIK3CD C416 single residue R:2 0.0177652807514415 2 testis:2
GNAQ G48 single residue *:1|L:1|V:1 0.0178075460389295 3 eye:3
ATM I2888 single residue T:3|L:1 0.0178317087176485 4 bladder:1|breast:1|lung:1|skin:1
PTEN H61 single residue R:4|N:1|Y:1 0.0179437943852943 6 brain:2|breast:1|lung:1|pancreas:1|uterus:1
CARD11 E93 single residue D:2|K:1|Q:1 0.0182330764776687 4 lymph:3|skin:1
TP53 I254 single residue S:7|V:2|F:1|L:1|M:1|N:1 0.0184452967314114 13 bowel:3|lung:3|liver:2|pancreas:2|brain:1|breast:1|stomach:1
ERBB3 R103 single residue H:2|R:2|G:1 0.0184874894301309 5 bladder:3|bowel:1|uterus:1
FAM58A X141 single residue sp:4 0.0186113922627832 4 skin:2|breast:1|lung:1
CDH1 R63 single residue *:6|G:1|P:1 0.0187372466896063 8 breast:5|bladder:2|brain:1
PIK3CA E970 single residue K:9 0.0189638488402124 9 breast:4|bowel:2|bladder:1|head_neck:1|stomach:1
EP300 Q1455 single residue H:4|Q:1|R:1 0.0189801339276453 6 bladder:6
HNF1A S591 single residue S:2|Y:1 0.0197331659963799 3 stomach:3
AKT1 D323 single residue G:2|Y:2|N:1 0.0198991094867804 5 bladder:1|breast:1|kidney:1|lung:1|prostate:1
FBXW7 S546 single residue L:7|*:1|P:1 0.0203093632196684 9 bladder:6|head_neck:1|kidney:1|prostate:1
ERBB2 R138 single residue Q:2|W:1 0.0204568143885468 3 skin:3
ANKRD11 K369 single residue R:5 0.0204755008151429 5 skin:2|testis:2|brain:1
MTOR A1459 single residue D:4|P:1|V:1 0.0209022099858904 6 kidney:2|bowel:1|brain:1|lung:1|soft_tissue:1
GTF2I F641 single residue F:3|C:1 0.0209524305200254 4 skin:3|pancreas:1
TGFBR1 T375 single residue I:1|K:1|R:1 0.0210047882793745 3 bowel:3
PIK3CB R321 single residue Q:9 0.0210357822915523 9 bowel:5|breast:1|skin:1|stomach:1|uterus:1
ERRFI1 K409 single residue N:2|Q:1 0.0212231821625514 3 bowel:3
INPPL1 R70 single residue H:4 0.0222950140334926 4 stomach:4
ARID1B G966 single residue D:4 0.0223082832237321 4 pancreas:3|head_neck:1
ERBB2 T733 single residue I:4 0.0223243040785117 4 bladder:2|bowel:1|uterus:1
CBFB M1 single residue T:2|I:1|K:1 0.0223684139186518 4 breast:4
ETV6 R369 single residue W:6|L:1|Q:1|R:1 0.0227397135597969 9 bowel:5|bladder:1|brain:1|lung:1|uterus:1
TGFBR2 R520 single residue *:8|R:1 0.0229676164484648 9 pancreas:4|skin:2|bowel:1|lung:1|stomach:1
NF1 R461 single residue *:7|Q:2 0.0230323354914211 9 uterus:4|lung:2|adrenal_gland:1|brain:1|stomach:1
PTPN11 T468 single residue M:6|T:1 0.0231427297174703 7 bowel:3|skin:2|stomach:2
EIF1AX N4 single residue S:2|I:1|Y:1 0.0232127972275248 4 bowel:1|eye:1|ovary:1|thymus:1
EIF1AX X6 single residue sp:5 0.0232127972275248 5 bowel:2|eye:1|ovary:1|prostate:1
CDK12 R890 single residue H:5 0.0234944216172339 5 bowel:5
PTEN L247 single residue *:3|F:1 0.0240582123723414 4 brain:1|lung:1|pancreas:1|uterus:1
CTLA4 T17 single residue A:5 0.0243721545716862 5 pancreas:2|bowel:1|liver:1|lymph:1
BCL10 N173 single residue H:2 0.0244964388236978 2 pancreas:2
SMO V414 single residue A:1|G:1|V:1 0.024540518150126 3 cervix:2|lung:1
LYN I364 single residue L:1|N:1 0.0246336640316435 2 bladder:2
MSH2 E580 single residue *:6 0.0248537133655945 6 bowel:5|uterus:1
MET H1094 single residue Y:3|R:1 0.0248978857348268 4 kidney:3|lung:1
PBRM1 X856 single residue sp:4 0.0256762205674686 4 kidney:4
CTNNB1 R535 single residue *:5|Q:2 0.0258177624043666 7 stomach:4|breast:1|head_neck:1|uterus:1
TP53 I232 single residue S:4|F:3|N:3|T:3|I:1 0.0262978898298508 14 bowel:4|breast:2|blood:1|brain:1|lung:1|lymph:1|ovary:1|prostate:1|skin:1|uterus:1
SMARCD1 R183 single residue Q:5|*:1|L:1 0.0268785172725617 7 bowel:2|uterus:2|biliary_tract:1|skin:1|thyroid:1
PIM1 L2 single residue F:5|V:1 0.0269741273167823 6 lymph:6
FOXA1 R219 single residue C:3|S:3|G:1|R:1 0.0270600943919014 8 prostate:4|bowel:2|brain:1|skin:1
IL7R R206 single residue *:8|Q:1 0.0272338648312328 9 skin:8|stomach:1
PIM1 E79 single residue D:4|E:2 0.0274181876571439 6 lymph:6
RAC1 P34 single residue R:3|H:1|S:1 0.0277542866088587 5 testis:3|skin:1|stomach:1
DICER1 S1344 single residue L:6|I:1 0.0280566878520535 7 skin:4|uterus:2|biliary_tract:1
PPM1D E525 single residue *:8 0.0280916443660421 8 uterus:5|brain:2|bowel:1
NOTCH1 R365 single residue C:6|S:2 0.0280924657963512 8 stomach:3|skin:2|bladder:1|brain:1|lung:1
CDKN2A D74 single residue N:3|Y:3|G:1|V:1 0.0289475395986871 8 lung:3|head_neck:2|breast:1|skin:1|stomach:1
DNMT1 E432 single residue K:7 0.0293011171345867 7 bowel:5|bladder:1|stomach:1
MET Y1003 single residue *:1|C:1|F:1 0.0296559961244166 3 lung:3
AXIN1 X652 single residue sp:3 0.0296833082515064 3 liver:3
KEAP1 V155 single residue F:4|A:1 0.0299449285971264 5 lung:5
STK11 W239 single residue C:3|*:1|S:1 0.0302867868500955 5 lung:5
FGFR3 L8 single residue L:4 0.0302990211029827 4 lung:3|skin:1
RNF43 R145 single residue *:9 0.030502281384959 9 pancreas:4|bowel:3|bladder:1|stomach:1
RNF43 R132 single residue *:11 0.030502281384959 11 bowel:6|pancreas:3|stomach:1|uterus:1
EPAS1 Y532 single residue C:2 0.0308917177568844 2 adrenal_gland:2
CD79B X185 single residue sp:3 0.031280397627826 3 lymph:3
POLE E18 single residue K:7 0.0316821444512517 7 breast:3|bladder:2|lung:2
CARD11 R337 single residue Q:3|*:2 0.0317184527354723 5 lymph:3|bowel:1|soft_tissue:1
CARD11 E626 single residue K:4|*:1|Q:1 0.0317184527354723 6 lymph:3|lung:2|cervix:1
RBM10 X91 single residue sp:5 0.0317436063416975 5 lung:5
PTPN11 T507 single residue K:3 0.0318523642648974 3 brain:3
PTPN11 D61 single residue Y:3|N:1 0.0318523642648974 4 brain:3|blood:1
NOTCH1 C440 single residue F:2|R:1|S:1|W:1 0.0322228079201374 5 head_neck:3|brain:1|stomach:1
NOTCH1 G310 single residue R:6|E:1 0.0322228079201374 7 brain:3|skin:3|head_neck:1
ERBB3 R475 single residue W:8 0.0325525423143691 8 bowel:3|stomach:2|bladder:1|skin:1|uterus:1
SMAD3 R268 single residue C:7|H:4 0.0327038445077706 11 bowel:7|lung:1|pancreas:1|stomach:1|uterus:1
SMAD3 R287 single residue W:6|Q:2 0.0327038445077706 8 bowel:3|bladder:1|breast:1|pancreas:1|skin:1|stomach:1
HNF1A I27 single residue L:4 0.0328297064281064 4 lymph:2|bladder:1|bowel:1
PRDM14 R505 single residue H:4|C:2 0.0330881832795661 6 bowel:4|skin:1|uterus:1
CDKN1B X159 single residue sp:8 0.0331705164414828 8 brain:2|breast:2|kidney:2|bladder:1|liver:1
CDKN1B G72 single residue D:3|G:2|A:1 0.0331705164414828 6 bladder:1|bowel:1|lymph:1|prostate:1|stomach:1|thyroid:1
ETV6 S284 single residue S:4|F:2 0.0332331004976096 6 skin:5|breast:1
CASP8 X243 single residue sp:7 0.0339327707674888 7 head_neck:3|skin:2|lung:1|uterus:1
MAP2K4 X347 single residue sp:5 0.0340442289468374 5 breast:2|bladder:1|bowel:1|stomach:1
SMARCA4 E821 single residue K:7|D:1 0.0348588465012058 8 bladder:4|brain:1|kidney:1|skin:1|testis:1
ALK R395 single residue H:6|R:1 0.035124603778631 7 bowel:2|head_neck:1|lung:1|skin:1|soft_tissue:1|stomach:1
CIC X151 single residue sp:6 0.0353206266313835 6 brain:3|lung:1|lymph:1|stomach:1
NOTCH1 E455 single residue K:6|E:1 0.0354105169074645 7 head_neck:4|lung:1|skin:1|stomach:1
TP53 Q165 single residue *:15|H:1 0.0355589841732736 16 lung:3|prostate:3|breast:2|lymph:2|pancreas:2|bladder:1|soft_tissue:1|stomach:1|unk:1
PIK3CA R357 single residue Q:4|*:1|G:1|L:1 0.036188804599893 7 bowel:5|kidney:1|uterus:1
STK11 G251 single residue V:3|C:2|R:1 0.0363127834198724 6 lung:5|bowel:1
ARID1B Q1179 single residue *:4|P:1 0.0366275919271872 5 skin:4|lung:1
ARID1A Q1142 single residue *:6 0.0366563874985603 6 liver:2|bone:1|kidney:1|stomach:1|unk:1
RPTOR R139 single residue H:8 0.0367985047325461 8 uterus:2|bladder:1|bowel:1|cervix:1|pancreas:1|prostate:1|skin:1
SF3B1 Y623 single residue C:2|H:1|S:1 0.0377723571915572 4 bone:1|breast:1|liver:1|pleura:1
BRCA2 S2303 single residue S:3|F:2 0.0384535851439601 5 skin:5
RB1 X463 single residue sp:5 0.038464461387127 5 lung:2|liver:1|soft_tissue:1|thyroid:1
PTPRT R364 single residue Q:6|*:4|R:2 0.0388462009711605 12 skin:5|brain:2|bowel:1|kidney:1|lung:1|unk:1|uterus:1
SETD2 H1603 single residue R:3|Y:2 0.0393590702541361 5 skin:3|brain:1|head_neck:1
MAX R36 single residue W:2 0.039885672997618 2 blood:2
AXL T443 single residue T:2 0.0400800119264523 2 bladder:2
RB1 Y606 single residue *:2|C:2 0.040781933771183 4 head_neck:2|bladder:1|breast:1
CCND3 Q276 single residue *:4 0.0408951890448411 4 stomach:2|bowel:1|lymph:1
SMARCB1 R374 single residue Q:5|W:3 0.0409234978178552 8 bowel:2|stomach:2|brain:1|breast:1|pancreas:1|unk:1
CUL3 A20 single residue A:5 0.0414950238120077 5 skin:4|brain:1
BCL10 E178 single residue E:2|D:1 0.0416290007485654 3 pancreas:2|prostate:1
KDM6A X1246 single residue sp:4 0.0416332513899781 4 bladder:1|cervix:1|head_neck:1|lung:1
TGFBR1 R487 single residue Q:5|W:3 0.0420025722530218 8 pancreas:2|bladder:1|bowel:1|lung:1|skin:1|stomach:1|uterus:1
PTPN11 A461 single residue T:4|G:1 0.0426694130573166 5 brain:3|skin:1|uterus:1
PTEN G251 single residue V:4|A:1|D:1 0.043019639792546 6 skin:2|uterus:2|brain:1|stomach:1
PTEN T277 single residue I:3|*:1|A:1|N:1 0.043019639792546 6 brain:3|bowel:1|ovary:1|uterus:1
FGFR2 F276 single residue C:2|I:1 0.0435896107854571 3 biliary_tract:2|bladder:1
STK11 X125 single residue sp:5 0.0436726212124469 5 lung:2|bladder:1|stomach:1|unk:1
NSD1 C1710 single residue *:1|S:1|Y:1 0.0438691837339285 3 head_neck:3
SMAD4 A118 single residue V:11 0.0442845520213532 11 bowel:4|pancreas:3|ampulla_of_vater:1|breast:1|head_neck:1|stomach:1
CTCF H288 single residue D:1|R:1|Y:1 0.0444979719260984 3 breast:3
PIK3R1 X434 single residue sp:5 0.0447131965725729 5 brain:1|breast:1|ovary:1|prostate:1|skin:1
VHL L169 single residue P:5 0.0448753895749222 5 kidney:5
KNSTRN C22 single residue Y:3|S:1 0.0449961288692079 4 lung:2|skin:1|stomach:1
PPP2R1A R182 single residue W:6|R:1 0.0450904673732307 7 uterus:2|bladder:1|breast:1|lung:1|stomach:1|thyroid:1
ERRFI1 K116 single residue *:2 0.0452215429932304 2 liver:2
SMAD4 Y353 single residue N:2|C:1|D:1 0.0453956226948068 4 biliary_tract:1|lung:1|prostate:1|stomach:1
SMAD4 Y95 single residue C:2|*:1|H:1 0.0453956226948068 4 lung:2|biliary_tract:1|pancreas:1
TCF3 N551 single residue K:2 0.04594352537914 2 lymph:2
RPS6KA4 R629 single residue C:4|H:2|R:1 0.0462995364318378 7 skin:3|bowel:2|lung:1|prostate:1
RPS6KA4 S236 single residue L:5|S:1 0.0462995364318378 6 lung:2|bladder:1|bowel:1|skin:1|unk:1
CBFB W73 single residue *:4 0.0469416259904556 4 breast:4
PTEN L320 single residue *:2|S:1|V:1 0.0469972383599729 4 biliary_tract:1|lung:1|prostate:1|uterus:1
CREBBP W1472 single residue C:2|R:2|G:1|S:1 0.0475077738779973 6 head_neck:2|lymph:2|bladder:1|lung:1
CREBBP Y1482 single residue C:1|D:1|H:1|N:1 0.0475077738779973 4 bladder:2|lymph:2
FH M336 single residue I:1|L:1 0.0475803468275849 2 liver:2
NUP93 A733 single residue A:2 0.0475973579366498 2 lymph:2
RECQL4 X766 single residue sp:6 0.0477088999412308 6 bowel:4|lymph:2
EIF1AX G8 single residue R:5|E:1 0.0479490680133651 6 eye:2|cervix:1|ovary:1|skin:1|thyroid:1
RAD52 R396 single residue H:1|R:1 0.0481336856829914 2 skin:2
VHL L135 single residue *:2|F:2 0.0482434197400611 4 kidney:4
HNF1A R114 single residue H:3|C:1|L:1 0.049626346636423 5 uterus:3|bladder:1|lung:1
HGF G229 single residue A:2|D:1 0.0500918154904944 3 cervix:2|brain:1
HNF1A G338 single residue G:3|A:1 0.0514682162685184 4 prostate:3|stomach:1
TP53 P190 single residue L:12|T:3|R:1|S:1 0.0517990181016758 17 bowel:6|brain:3|prostate:3|kidney:1|liver:1|lung:1|lymph:1|pancreas:1
KEAP1 R320 single residue L:3|Q:2|M:1|P:1|W:1 0.0522547519433849 8 lung:6|breast:1|thyroid:1
FBXW7 X195 single residue sp:5 0.052851995591814 5 stomach:2|bowel:1|head_neck:1|lung:1
FBXW7 R441 single residue W:3|G:2|L:1|Q:1 0.052851995591814 7 lung:2|uterus:2|bowel:1|breast:1|soft_tissue:1
CDKN1A M1 single residue V:2|I:1|R:1 0.0534198544524845 4 liver:3|brain:1
IRF4 Y428 single residue *:1|H:1 0.0553803010201321 2 skin:2
TBX3 W113 single residue *:3|R:1 0.0557812775205636 4 breast:3|stomach:1
KDR C482 single residue R:2|*:1 0.0557974190648336 3 lymph:2|lung:1
KMT2A R1264 single residue *:5 0.0567129807987362 5 bladder:3|head_neck:1|stomach:1
ERBB3 N126 single residue K:3|I:1 0.0570727711745951 4 bladder:1|bowel:1|prostate:1|stomach:1
TP53 V197 single residue L:5|V:5|E:3|M:3|G:1 0.057198430388418 17 lung:5|stomach:3|breast:2|liver:2|bladder:1|bowel:1|brain:1|ovary:1|pancreas:1
SMAD4 G510 single residue *:2|R:2|A:1|E:1 0.0574589531183325 6 bowel:3|lung:1|pancreas:1|stomach:1
ATRX R907 single residue *:6 0.0576614283782519 6 brain:5|prostate:1
TSC1 X797 single residue sp:4 0.0580126611145658 4 uterus:2|bladder:1|skin:1
PLK2 L208 single residue P:2|V:1 0.0580752072255424 3 stomach:2|breast:1
PTEN X267 single residue sp:5 0.0584505522716062 5 bowel:1|brain:1|lung:1|thyroid:1|uterus:1
STK11 W308 single residue L:3|C:2|*:1 0.0593665276447652 6 lung:5|biliary_tract:1
TP53 M133 single residue K:5|R:3|I:1|T:1 0.0598449339561851 10 breast:4|bowel:1|head_neck:1|lung:1|pancreas:1|skin:1|stomach:1
KRAS K5 single residue E:3 0.060055464862559 3 blood:1|bowel:1|brain:1
NF1 R1870 single residue Q:7|W:1 0.0602895567764422 8 skin:3|brain:2|bowel:1|stomach:1|uterus:1
EPHA7 G656 single residue E:6|G:3|R:1|W:1 0.0608812153658397 11 skin:9|brain:1|head_neck:1
ERBB2 V697 single residue L:4 0.0611219878744376 4 bowel:1|breast:1|unk:1|uterus:1
PTPRS Y398 single residue Y:4 0.0611495944281989 4 pancreas:3|uterus:1
HIST1H3H K37 single residue M:3|E:1 0.0613363986989126 4 bladder:1|head_neck:1|lung:1|skin:1
KEAP1 R601 single residue L:4|W:2 0.0615590624356438 6 lung:6
RAD51C Y224 single residue H:2 0.0615844369795179 2 bladder:2
RAD51C P21 single residue S:2|A:1|T:1 0.0616334079268701 4 breast:3|bladder:1
BCL2L11 G156 single residue R:3|E:2|*:1 0.061848349524064 6 uterus:2|cervix:1|lung:1|stomach:1|unk:1
EZH2 K665 single residue E:1|R:1 0.0620628563514022 2 lymph:2
MAP2K4 R110 single residue *:4|Q:2|L:1|P:1 0.0625969845163816 8 uterus:2|breast:1|lung:1|ovary:1|pancreas:1|stomach:1|thyroid:1
TP53 H178 single residue D:5|P:3|Q:2|H:1|N:1 0.0627913608262321 12 uterus:3|brain:2|ovary:2|unk:2|biliary_tract:1|kidney:1|skin:1
SPRED1 R349 single residue S:1|W:1 0.0638652407183754 2 bladder:2
TP53 V218 single residue G:5|E:1|L:1|M:1|V:1 0.0643906580986468 9 bladder:2|head_neck:2|skin:2|lung:1|lymph:1|unk:1
SETD2 X1572 single residue sp:6 0.0645658226264237 6 kidney:3|bowel:1|lung:1|stomach:1
CIC P203 single residue S:2|A:1|L:1 0.0647601453800692 4 brain:3|uterus:1
KMT2C R56 single residue Q:6|*:4 0.0649389721368166 10 uterus:4|bowel:3|breast:1|head_neck:1|lung:1
KMT2C R4549 single residue C:7|H:1|S:1 0.0649389721368166 9 bladder:2|skin:2|bowel:1|breast:1|pancreas:1|prostate:1|unk:1
MEF2B K4 single residue E:4 0.065125088740109 4 lymph:4
RIT1 A77 single residue T:3|P:1|S:1 0.0651692609390733 5 lung:2|biliary_tract:1|bowel:1|uterus:1
PTEN I67 single residue T:2|K:1|V:1 0.0651819173076579 4 breast:1|ovary:1|soft_tissue:1|uterus:1
PPP4R2 *418 single residue L:1|Y:1 0.0652217461803095 2 skin:2
PIK3CD R894 single residue R:4|Q:1 0.0656422395683915 5 stomach:3|prostate:2
KDM6A X76 single residue sp:3 0.0657879846054171 3 bladder:3
ERBB4 F1102 single residue C:4|F:1 0.0659327405024936 5 stomach:3|bladder:1|bowel:1
ATM R2832 single residue C:6|S:1 0.066057625068094 7 lung:2|brain:1|breast:1|skin:1|stomach:1|thyroid:1
TET2 R550 single residue *:7 0.0664756506292094 7 blood:2|bowel:1|head_neck:1|lymph:1|unk:1|uterus:1
SMAD2 R182 single residue *:7|R:1 0.068135086582833 8 bowel:4|uterus:2|head_neck:1|prostate:1
BCL2 N172 single residue S:3|N:2|Q:1 0.0692871398183635 6 lymph:5|bowel:1
FGFR2 P253 single residue R:4|L:2 0.0694872697601985 6 lung:2|bowel:1|breast:1|ovary:1|uterus:1
PTEN Y174 single residue *:2|D:1|H:1 0.07120415463729 4 breast:2|brain:1|skin:1
MET T222 single residue T:7 0.0714242435038856 7 skin:5|uterus:2
BRAF X327 single residue sp:3 0.0717947351386339 3 skin:2|lung:1
TGFBR1 I259 single residue I:2|N:1 0.0725830208046979 3 cervix:2|skin:1
ERBB4 S774 single residue G:2|N:1|R:1 0.0732416810636865 4 stomach:4
CCND1 C47 single residue S:3|G:1 0.0733365452924601 4 lymph:3|blood:1
ARID1A X911 single residue sp:5 0.0734346156772229 5 lung:2|biliary_tract:1|bladder:1|skin:1
ERBB2 A293 single residue T:4|P:1|V:1 0.0736415328665745 6 bowel:2|lung:1|ovary:1|skin:1|unk:1
ERBB2 I767 single residue M:9 0.074155571453423 9 bladder:4|breast:3|bowel:1|head_neck:1
BRD4 P1065 single residue P:3|R:1 0.0743406064704526 4 skin:3|stomach:1
KDM6A X129 single residue sp:5 0.0772719082059661 5 bladder:3|head_neck:1|kidney:1
PGR R836 single residue Q:8|*:1 0.0776186817443919 9 skin:5|bowel:2|brain:1|uterus:1
PTPRS R1492 single residue W:4|Q:3|R:1 0.0779048132747687 8 bowel:3|stomach:2|bladder:1|head_neck:1|kidney:1
CBL C384 single residue R:3|W:1 0.0780706952247139 4 brain:2|skin:1|soft_tissue:1
EPHA3 R136 single residue *:11 0.0785022930658572 11 skin:7|unk:3|uterus:1
PBRM1 R921 single residue *:7 0.0788067006506364 7 adrenal_gland:1|bowel:1|brain:1|head_neck:1|kidney:1|lung:1|uterus:1
HIST1H1C E115 single residue K:4 0.079068457929701 4 breast:4
KDM6A Q1003 single residue *:2|P:1 0.0794831369685882 3 bladder:3
MAP3K13 X502 single residue sp:4 0.0818345274306637 4 stomach:3|prostate:1
PDGFRA C235 single residue Y:2|R:1|S:1 0.0823670577038415 4 brain:3|skin:1
ERCC3 L713 single residue L:2 0.083015618806217 2 blood:2
PTEN I101 single residue T:4 0.083264069890969 4 brain:2|soft_tissue:1|unk:1
NFE2L2 I28 single residue T:3 0.0834734884151312 3 head_neck:1|lung:1|pancreas:1
CDH1 Y190 single residue C:3 0.0839076552994752 3 stomach:3
APC S1315 single residue *:8 0.0850521110220947 8 bowel:8
IRS2 G1057 single residue D:3 0.0854265037781273 3 lymph:2|bowel:1
PIM1 N7 single residue N:4 0.0854284093090971 4 lymph:4
SMAD2 C463 single residue *:3|F:1 0.0862675631729402 4 bowel:4
SMAD2 R321 single residue Q:5|*:4 0.0862675631729402 9 bowel:6|stomach:3
SPOP K129 single residue E:3 0.086449492395681 3 prostate:3
CARD11 R423 single residue Q:3|W:2|R:1 0.0866304024478113 6 bowel:5|lung:1
TRAF7 R189 single residue L:1|P:1|R:1|W:1 0.086969413826998 4 lung:3|bladder:1
KIT R888 single residue Q:3|W:3|R:1 0.0873753872499497 7 bowel:2|adrenal_gland:1|liver:1|ovary:1|soft_tissue:1|uterus:1
IKZF1 E304 single residue K:7|Q:1 0.0875564839666501 8 skin:6|bladder:1|unk:1
RHOA L69 single residue P:2|R:2|M:1 0.0884860446408663 5 lymph:2|stomach:2|bowel:1
CASP8 R494 single residue *:8 0.0886117863611851 8 head_neck:3|bladder:1|cervix:1|lung:1|stomach:1|uterus:1
TNFRSF14 C111 single residue W:2|Y:1 0.0888304463274096 3 bladder:2|lymph:1
PMS2 K651 single residue R:4 0.089408084970774 4 testis:2|brain:1|soft_tissue:1
MAP2K1 N122 single residue D:3 0.089479789390335 3 lung:1|lymph:1|stomach:1
SDHAF2 S10 single residue L:3|*:1|A:1 0.090116860936781 5 lung:3|cervix:1|kidney:1
RAC1 K135 single residue N:1|R:1 0.0909173130305242 2 head_neck:2
CCND1 E9 single residue E:3|D:1|K:1 0.0910705118800777 5 blood:2|bowel:1|breast:1|lymph:1
EIF4A2 M1 single residue I:1|K:1|R:1|V:1 0.0913429534541545 4 breast:1|lung:1|prostate:1|skin:1
CREBBP I1431 single residue I:1|N:1|S:1|V:1 0.0936694562481603 4 bladder:2|head_neck:1|lymph:1
ARID1B T1652 single residue M:3|A:1|T:1 0.0938231260288271 5 skin:2|bladder:1|bowel:1|stomach:1
VHL W117 single residue L:3|*:2|C:1 0.094271768237484 6 kidney:5|pancreas:1
VHL Y112 single residue *:2|C:1|D:1|Y:1 0.094271768237484 5 kidney:3|brain:1|pancreas:1
WHSC1 T1150 single residue A:3 0.0946426518532276 3 lymph:2|brain:1
SMAD4 S178 single residue *:9 0.0946588953701679 9 pancreas:3|bowel:2|stomach:2|bladder:1|cervix:1
SOS1 A90 single residue A:3|T:1|V:1 0.0949773985392201 5 skin:2|brain:1|kidney:1|lung:1
SMAD2 T303 single residue R:2|I:1 0.0953428440091016 3 bowel:3
RB1 X406 single residue sp:9 0.0953651983533237 9 breast:2|bladder:1|brain:1|liver:1|lung:1|ovary:1|pancreas:1|prostate:1
EP300 L415 single residue P:3 0.0954266946248702 3 lymph:2|bladder:1
SMARCA4 R1157 single residue W:4|Q:3 0.09557979887796 7 bladder:2|bowel:2|lymph:1|skin:1|thymus:1
PTEN W274 single residue *:6|S:1 0.0955805982587405 7 brain:3|uterus:2|breast:1|skin:1
PTEN Y65 single residue *:5 0.0955805982587405 5 uterus:2|brain:1|cervix:1|kidney:1
SMAD2 P305 single residue L:2|Q:1|T:1 0.0969117927764253 4 bowel:3|prostate:1
SF3B1 V701 single residue F:2|A:1|I:1 0.0969151861465262 4 blood:1|lung:1|lymph:1|skin:1
NOTCH1 I471 single residue T:4 0.098353622293025 4 stomach:2|head_neck:1|pancreas:1
RAC1 C18 single residue Y:2|F:1|S:1 0.0992431503740995 4 head_neck:2|bowel:1|lung:1
CTCF M1 single residue V:2|I:1|T:1 0.0997648063724961 4 breast:1|pancreas:1|soft_tissue:1|stomach:1
STK11 G196 single residue V:4|G:1|R:1 0.0999093296754989 6 lung:3|bowel:1|skin:1|unk:1
STK11 X200 single residue sp:5 0.0999093296754989 5 lung:4|unk:1
FBXW7 T385 single residue K:2|I:1|P:1 0.0999935786199138 4 bladder:1|blood:1|stomach:1|uterus:1
FBXW7 R393 single residue *:4|Q:3 0.0999935786199138 7 bowel:2|biliary_tract:1|head_neck:1|pancreas:1|stomach:1|uterus:1
SMARCA4 546 in-frame indel K546del:5 0.000230672905611517 5 brain:4|lymph:1
CDKN2A 27-42 in-frame indel V28_E33del:4|L32_L37del:3|A36_N39delinsD:1|E27del:1|G35_A36del:1|N39_N42del:1|R29_A34del:1 8.77193090544841e-05 12 lung:3|stomach:3|skin:2|bladder:1|cervix:1|head_neck:1|pancreas:1
SMAD4 357-377 in-frame indel R361_G365del:2|C363del:1|F362_H371del:1|G358_D360del:1|G365_E377del:1|R361_L364del:1|S357_G365del:1 3.6822392551777e-06 8 pancreas:3|stomach:3|bowel:2
SMAD4 536-546 in-frame indel L536_E538delinsQ:2|D537_E538dup:1|L540del:1|V539_A546del:1 0.0247790280835321 5 stomach:2|biliary_tract:1|bladder:1|bowel:1
BAP1 25-34 in-frame indel E31del:2|K25_D34delinsN:1|K25_Q28del:1|Y33del:1 0.0475318811088585 5 brain:1|eye:1|kidney:1|pleura:1|skin:1
SMARCB1 364 in-frame indel K364del:5 0.000385365731765089 5 brain:2|stomach:2|biliary_tract:1
FOXA1 249-409 in-frame indel F254_N256delinsY:6|E255_N256del:2|G251_F254del:2|G251_G257del:2|S250_Y259del:2|A323_P326del:1|C258_R261del:1|D249_F254del:1|D249_N252del:1|F254_E255del:1|F254_G257delinsC:1|F254_L260del:1|G284_G290del:1|K264_K267del:1|K264dup:1|K267dup:1|M253_N256del:1|M253_Y259del:1|N252_C258del:1|N252_G257del:1|N252_S408del:1|N397_F400del:1|Q263_C268del:1|Q263_D296delinsH:1|Q263_G281del:1|Q263del:1|R265_K270del:1|S250_F254del:1|S250_N252del:1|S282_G283dup:1|S409del:1 6.25580148545088e-73 40 prostate:34|breast:6
MED12 41-55 in-frame indel G44_F45del:1|K42_N46del:1|N46_S52del:1|P49_E55del:1|V41_S52del:1 7.95052431352778e-07 5 breast:3|bladder:1|bowel:1
CEBPA 307-311 in-frame indel N307_E309delinsK:1|T310_Q311insKQNP:1|T310_Q311insW:1|V308dup:1 0.00506139021814322 4 blood:4
PIK3R1 439-470 in-frame indel E451_Y452del:6|D464_Y467del:4|F456_Q457del:3|K459del:3|L449del:3|N441_T454del:3|E458del:2|E462_R465del:2|H450_E451insVH:2|K448_N453del:2|N453del:2|Q455_F456insL:2|Q457_S460del:2|R461_E462delinsQ:2|Y452_Q457del:2|Y452dup:2|D440_E451del:1|D440_K448del:1|D440del:1|D464_E468dup:1|D464_Y470dup:1|E439del:1|E451del:1|E458_K459del:1|E458_Y463dup:1|E462_Y463delinsD:1|E462dup:1|E468_E469insGEYDRLYE:1|E468_E469insGLYE:1|E468_Y470dup:1|F456_K459del:1|G446_E451del:1|G446_L449delinsV:1|H450_E451del:1|H450_E451dup:1|H450_E451insD:1|H450_K459del:1|H450_Q455dup:1|H450_T454del:1|H450del:1|I442_E443delinsK:1|I442_N453del:1|K448_Y452del:1|L449_H450insQ:1|L449_K459del:1|L449_Q455del:1|L466_E469del:1|L466_Y470delinsF:1|L466del:1|N453_D464dup:1|N453_Q455delinsK:1|N453_Q457del:1|N453_Y463del:1|Q455_K459del:1|Q455_S460dup:1|Q457_E462del:1|R465_Y467del:1|R465dup:1|S460_D464del:1|Y452_N453insF:1|Y463_E468dup:1|Y467_Y470del:1 9.34522866603558e-183 88 uterus:31|brain:29|breast:11|bowel:4|lung:4|head_neck:3|stomach:3|ovary:2|soft_tissue:1
PIK3R1 558-582 in-frame indel T576del:6|K567_L570del:4|R574del:4|K567del:3|K575_R577del:2|R577del:2|D569_L570delinsV:1|D569_L581delinsE:1|D569dup:1|D578_M582delinsE:1|E558_K561del:1|E558_R562del:1|I566_P568delinsT:1|I571_K575del:1|I571_L581del:1|I571_Q572insR:1|I571_R574del:1|K567_I571del:1|K575_L581delinsM:1|K575_R577dup:1|K575_T576del:1|L570_D578del:1|L570_I571insY:1|L573_K575del:1|L573_R574del:1|L573del:1|M563_L570delinsI:1|M563_N564delinsI:1|N564_P568delinsT:1|P568_L573del:1|Q579_Y580delinsH:1|R577_D578del:1|R577_L581del:1|Y580_L581insF:1 8.12893453430381e-89 49 uterus:22|brain:7|breast:6|prostate:3|bowel:2|cervix:2|head_neck:2|lung:2|kidney:1|liver:1|stomach:1
PIK3R1 397-420 in-frame indel I405del:2|E403_L404del:1|E403_L404delinsV:1|I405_L420del:1|S399_L404del:1|T397_V401del:1|V401_H407del:1|V401_N406del:1|V402_L413del:1 4.95223936988698e-10 10 brain:4|uterus:4|bowel:1|breast:1
PIK3R1 378-380 in-frame indel L380del:3|K379del:1|N378del:1 0.00935831892553836 5 brain:3|breast:2
TP53 229-292 in-frame indel I255del:9|L252del:3|L265del:3|E286_E287del:2|N235del:2|N239_S240del:2|N239_S241del:2|N239dup:2|S241dup:2|T253dup:2|T256_S260del:2|V274_C275dup:2|A276_C277dup:1|A276_E285del:1|C229_H233del:1|C229_T230del:1|C238_M243del:1|C238_N239delinsY:1|C238_S240del:1|C275_R282delinsW:1|C277dup:1|D281_R282insP:1|E285_K292del:1|F270del:1|G244_M246delinsV:1|G245_P250delinsA:1|G262del:1|I254_T256del:1|I255dup:1|L252_I254del:1|L252dup:1|L264_N268del:1|M237_N239del:1|M243_I255del:1|N235_Y236dup:1|N263_N268del:1|N268_R273del:1|P250_I251delinsL:1|P250_L252del:1|R282_R283del:1|S240_C242del:1|S240_S241del:1|S260_L264dup:1|S269_E271del:1|S269_E271delinsK:1|T231_I232del:1|T231_I232insTDCTT:1|T253_L257del:1|T256del:1|V272_R273insL:1|V274_G279del:1|V274dup:1|Y234_M237del:1|Y234del:1|Y236_M237delinsL:1 1.46521691051924e-64 76 lung:14|bowel:12|stomach:11|brain:8|ovary:6|head_neck:5|unk:4|breast:3|pancreas:3|soft_tissue:3|uterus:3|lymph:1|prostate:1|skin:1|thyroid:1
TP53 128-163 in-frame indel N131del:4|R156del:2|V157_R158del:2|A138_L145del:1|A138_P142del:1|A159del:1|A161_I162del:1|C135_L137delinsW:1|C141_P142del:1|D148_T150del:1|D148_T155dup:1|D148del:1|G154_T155del:1|I162_Y163delinsN:1|I162dup:1|K139_P142delinsT:1|L130_A138dup:1|L130del:1|P128_L130del:1|P128del:1|P142dup:1|P153_G154del:1|P153del:1|Q136_C141del:1|Q136del:1|R158_A159del:1|R158_A159dup:1|T150_R158del:1|T155_A161del:1|T155_R156del:1|T155_R158del:1|V143_P153del:1|V147_D148dup:1|V157_R158dup:1 2.55825013475141e-22 39 lung:8|brain:6|breast:6|ovary:4|stomach:4|bowel:2|head_neck:2|ampulla_of_vater:1|bladder:1|liver:1|pancreas:1|prostate:1|soft_tissue:1|uterus:1
TP53 173-187 in-frame indel P177_C182del:10|H178_S183del:2|C176_H179del:1|C176dup:1|E180_D184del:1|H179_D184del:1|H179del:1|P177_H178del:1|S183_G187delinsC:1|V173_R175del:1|V173dup:1 8.83278816666912e-07 21 stomach:4|breast:3|head_neck:3|bowel:2|adrenal_gland:1|brain:1|lung:1|ovary:1|pancreas:1|prostate:1|skin:1|soft_tissue:1|thyroid:1
TP53 191-206 in-frame indel P191del:11|G199_E204del:3|E204_L206del:1|I195_G199del:1|P191_L201del:1|Q192del:1|R202_L206del:1|V197_N200del:1 3.4723699042568e-06 20 brain:4|stomach:3|lung:2|ovary:2|prostate:2|soft_tissue:2|bowel:1|cervix:1|head_neck:1|pancreas:1|testis:1
PIK3CA 110-114 in-frame indel E110del:17|K111del:4|E110_K111dup:1|I112_L113del:1|K111_I112del:1|L113del:1|N114del:1 2.94617710868453e-59 26 brain:7|breast:6|uterus:5|bowel:4|head_neck:1|lung:1|prostate:1|soft_tissue:1
PIK3CA 436-466 in-frame indel E453del:4|E453_D454del:1|E453_P466del:1|E453_T462del:1|G451_D454del:1|G463_N465delinsD:1|H450_L455del:1|L436_P449dup:1|L452_G460del:1|L452_P458del:1|L455_G460delinsF:1|P447_L455del:1|P449_L452del:1|P449_L456del:1 4.11312718295531e-35 17 brain:7|breast:3|uterus:3|bowel:2|bone:1|stomach:1
PIK3CA 102-108 in-frame indel G106_R108del:3|G106_N107del:1|I102_E103delinsK:1|I102del:1|P104_V105del:1|R108del:1 5.94659702796749e-13 8 bowel:3|breast:3|uterus:2
PIK3CA 419-422 in-frame indel H419_C420del:3|H419_L422del:1 0.00024116143603727 4 breast:2|prostate:1|uterus:1
PIK3CA 10-18 in-frame indel L10_M16del:1|W11_H14delinsY:1|W11_P18del:1 0.0184009618681251 3 bladder:1|brain:1|uterus:1
ERBB2 772-775 in-frame indel Y772_A775dup:33|M774dup:1 1.41703102521153e-86 34 lung:25|breast:3|bladder:2|bowel:1|ovary:1|stomach:1|unk:1
ERBB2 778-780 in-frame indel G778_P780dup:12 7.40770850939387e-24 12 breast:6|lung:6
EGFR 745-759 in-frame indel E746_A750del:123|L747_T751del:9|L747_P753delinsS:8|E746_T751delinsA:3|L747_E749del:3|S752_I759del:3|L747_S752del:2|K745_E746insVPVAIK:1|K754_I759del:1|T751_A755del:1|T751_E758del:1 0 155 lung:155
EGFR 764-774 in-frame indel N771_H773dup:7|A767_V769dup:5|H773dup:5|S768_D770dup:4|D770_N771insG:1|D770_N771insGF:1|D770_N771insGL:1|D770_N771insY:1|D770_P772dup:1|H773_V774dup:1|N771_P772insH:1|N771_P772insHH:1|N771_P772insV:1|P772_H773dup:1|P772_H773insTPNP:1|Y764_D770dup:1 1.49808764272147e-72 33 lung:22|brain:6|bladder:4|uterus:1
EGFR 709-710 in-frame indel E709_T710delinsD:9 2.4645533400901e-13 9 lung:9
NOTCH1 356-359 in-frame indel F357del:17|S356del:2|C359del:1|Y358del:1 3.46745075162572e-40 21 brain:19|head_neck:2
NOTCH1 338 in-frame indel D338del:4 0.0110220456602372 4 brain:4
MDC1 1020-1028 in-frame indel K1025del:2|I1020_R1028del:1 0.0133207140057804 3 stomach:2|liver:1
SOX9 152-167 in-frame indel K167del:3|R152_K167del:1|R152del:1 0.0645000415402425 5 bowel:3|biliary_tract:1|stomach:1
CTNNB1 23-71 in-frame indel S45del:6|Y30_S33del:2|A43_P44dup:1|D32_I35delinsV:1|D32_S33del:1|D32_S37delinsA:1|G34_S71del:1|G38_P44del:1|L31_I35del:1|L31_S33del:1|P44_S60del:1|Q26_D32delinsH:1|Q28_D32delinsH:1|S23_S33del:1|S33_A39del:1|S45_P52del:1|T41_S45del:1|T41_S47del:1|T42_K49del:1|W25_D32del:1|W25_H36del:1 6.5334508895157e-60 27 liver:9|bowel:5|skin:4|adrenal_gland:3|lung:2|breast:1|ovary:1|prostate:1|stomach:1
MAP2K1 99-107 in-frame indel E102_I103del:4|I103_K104del:1|I99_K104del:1|P105_A106del:1|P105_I107delinsL:1 3.29106622127611e-12 8 skin:4|lung:2|blood:1|bowel:1
CREBBP 1680 in-frame indel S1680del:16 3.38918085369556e-29 16 lymph:7|bladder:2|bowel:2|brain:1|lung:1|penis:1|stomach:1|uterus:1
HIST1H1C 23 in-frame indel K23del:4 0.0155813440448199 4 bowel:3|breast:1
MTOR 1450-1468 in-frame indel A1459_D1468del:1|E1455_D1458dup:1|E1455_E1457dup:1|W1456_L1460delinsC:1|Y1450_W1456del:1 4.14767933010376e-08 5 bowel:2|kidney:2|uterus:1
KIT 550-580 in-frame indel W557_K558del:10|D579del:7|N566_P573del:2|Q556_D572del:2|V559_E561del:2|G565_T574delinsA:1|K550_P551del:1|K558_V560del:1|K558_V560delinsN:1|L576_H580dup:1|L576del:1|M552_E554delinsI:1|M552_V555del:1|M552_V555delinsI:1|M552_W557del:1|M552_Y570del:1|P551_M552delinsL:1|P551_V555del:1|P551_Y553delinsH:1|Q556_V560delinsH:1|Q575del:1|T574_H580dup:1|V559_G565del:1|V559_N566delinsD:1|V559_P573del:1|V560del:1|W557_E561del:1|W557_V559delinsF:1|Y553_E554del:1|Y570_L576del:1|Y578_D579insEQQLPY:1 1.9774818328683e-126 49 soft_tissue:39|skin:3|bowel:2|testis:2|breast:1|lung:1|vulva:1
KIT 502-503 in-frame indel A502_Y503dup:8 1.06961034696328e-12 8 soft_tissue:8
LATS2 479-480 in-frame indel P479_A480dup:12|P479_A480insPP:1 5.22537914260909e-29 13 stomach:4|lung:2|bladder:1|bowel:1|breast:1|kidney:1|prostate:1|testis:1|thymus:1
NFE2L2 21-42 in-frame indel D21_I22delinsE:1|D27del:1|E35_R42del:1|F37del:1|G31del:1|I22_D29del:1|I28dup:1|L30_S33del:1|R34_F37delinsL:1|R34_S40del:1|S33_R34del:1|W24_D29delinsY:1 7.43864692260498e-23 12 lung:8|stomach:2|bladder:1|liver:1
NFE2L2 73-87 in-frame indel E79del:1|L74_Q87del:1|L76_E82del:1|Q73_T80del:1 0.00016858469436721 4 breast:1|liver:1|lung:1|unk:1
ESR1 422 in-frame indel V422del:3 0.0451045963756131 3 breast:2|uterus:1
BRAF 592-604 in-frame indel T599dup:3|V600_K601delinsE:2|I592_A598dup:1|K601_W604del:1|V600_R603del:1 6.86065772143357e-11 8 bowel:2|lung:2|thyroid:2|prostate:1|skin:1
BRAF 486-494 in-frame indel N486_P490del:3|N486_A489delinsK:1|P490_Q494del:1|T488_P492del:1|T488_Q493delinsK:1 3.95006537267761e-09 7 pancreas:3|thyroid:2|blood:1|prostate:1
MYC 298 in-frame indel S298del:3 0.0205825305218148 3 bowel:1|head_neck:1|prostate:1
AKT2 60-84 in-frame indel C60_I75dup:1|L78_Q79insHANTFVIRCL:1|R67_L78dup:1|R76_I84dup:1 2.07162746898975e-05 4 breast:2|kidney:1|prostate:1
VHL 70-80 in-frame indel F76del:4|E70_R79dup:1|I75_C77del:1|R79_S80del:1 0.0935986091028419 7 kidney:6|pancreas:1
DAXX 457 in-frame indel E457del:4|E457dup:1 8.61079815107147e-06 5 pancreas:3|biliary_tract:1|lung:1
U2AF1 222-223 in-frame indel G222_G223del:1|G223del:1|G223dup:1 0.006574587762757 3 bladder:1|bowel:1|head_neck:1
ANKRD11 1461 in-frame indel K1461del:4 0.000507033000622495 4 bowel:1|skin:1|soft_tissue:1|uterus:1
ANKRD11 1008-1015 in-frame indel K1012del:2|E1008_P1015del:1 0.0372217722530266 3 head_neck:1|prostate:1|stomach:1
AKT1 65-77 in-frame indel P68_C77dup:1|T65_I75dup:1 0.0899335437451499 2 breast:2
STAT3 616 in-frame indel E616del:6 1.28595780031276e-08 6 lymph:3|lung:1|skin:1|stomach:1
SRSF2 92-117 in-frame indel P95_H99del:1|P95_R102del:1|P95_R117del:1|Y92_H100del:1|Y92_H99del:1 0.000120846881165768 5 eye:2|lymph:2|blood:1
FLT3 578-613 in-frame indel F594_D600dup:5|D586_E596dup:1|D593_F594insSPEDNEYFYVD:1|E598_F612dup:1|E598_Y599insSGSSDNEYFYVDFREYE:1|E598_Y599insVAYVDFREYE:1|E604_F605insSPRGGNEYFYVDFREYEYDLKWE:1|F594_R595insGTGSSDNEYFYVDF:1|F612_G613insQGFYVDFREYEYDLKWEFPRENLEF:1|L601_K602insNVDFREYEYDL:1|M578_E598dup:1|N587_D600dup:1|R595_E596insDYVDFR:1|R595_L601dup:1|S584_D600dup:1|S584_F605dup:1|S585_F594dup:1|Y597_E598insAGSSDNEYFYVDFREY:1|Y597_E598insDEYFYVDFREY:1|Y597_K602dup:1|Y599_D600insEYEYEYEY:1|Y599_D600insPAPQIMSTSTLISENMNIA:1|Y599_E604dup:1 9.64508469262637e-58 27 blood:27
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