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Stoltzman et al. PNAS 2008 Figure S1

This Github gist contains a CSV file of manually transcribed gene names from Figure S1 of Stoltzman et al. 2008 PNAS paper.

Another file containing the ENSEMBL gene identifiers matched to these ids has been produced via mygene.info API (Xin,2016)

References

  • Stoltzman, C., Peterson, C., Breen, K., Muoio, D., Billin, A., Ayer, D. (2008). Glucose sensing by MondoA:Mlx complexes: A role for hexokinases and direct regulation of thioredoxin-interacting protein expression Proceedings of the National Academy of Sciences 105(19), 6912-6917. https://dx.doi.org/10.1073/pnas.0712199105
  • Xin, J., Mark, A., Afrasiabi, C., Tsueng, G., Juchler, M., Gopal, N., Stupp, G., Putman, T., Ainscough, B., Griffith, O., Torkamani, A., Whetzel, P., Mungall, C., Mooney, S., Su, A., Wu, C. (2016). High-performance web services for querying gene and variant annotation Genome Biology 17(1), 91. https://dx.doi.org/10.1186/s13059-016-0953-9
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{
"cells": [
{
"cell_type": "code",
"execution_count": 1,
"metadata": {},
"outputs": [],
"source": [
"import pandas as pd\n",
"import mygene"
]
},
{
"cell_type": "code",
"execution_count": 2,
"metadata": {},
"outputs": [],
"source": [
"data = pd.read_csv('figure-s1.tsv', sep='\\t')"
]
},
{
"cell_type": "code",
"execution_count": 3,
"metadata": {},
"outputs": [],
"source": [
"symbols = data.stack().unique()"
]
},
{
"cell_type": "code",
"execution_count": 4,
"metadata": {},
"outputs": [
{
"data": {
"text/plain": [
"array(['ADAMTS15', 'ABL2', 'ANGPTL4', 'ADRA1B', 'ANKRD1', 'BBC3', 'ALS2',\n",
" 'C1orf79', 'BMP8A', 'ANGPT1', 'C3orf52', 'C10orf137', 'AQP10',\n",
" 'CCL3', 'CNOT2', 'ARC', 'CRYAB', 'CXCL14', 'ARHGAP6', 'CSF2',\n",
" 'CYR61', 'ARHGEF3', 'DST', 'DEFB103B', 'ARID3B', 'DUSP6', 'DGCR8',\n",
" 'ARID5B', 'EBI2', 'DRD4', 'ARRDC4', 'EDN1', 'DUSP1', 'AVPI1',\n",
" 'EPC1', 'DUX4', 'AXUD1', 'EYA3', 'ETS2', 'BACH1', 'FAM46C',\n",
" 'FLJ10404', 'BAMBI', 'FBN2', 'FTMT', 'BCL2A1', 'FGFR3', 'GLI4',\n",
" 'BCL6', 'GEM', 'GSX2', 'BHLHB2', 'GNPTAB', 'HCN2', 'BIRC3',\n",
" 'GRASP', 'HNRPDL', 'C11orf17', 'ID1', 'HS2ST1', 'C12orf42', 'IER3',\n",
" 'INSIG1', 'C13orf15', 'IL11', 'KCNQ10T1', 'C1orf63', 'IL1RL1',\n",
" 'KRTAP2-4', 'C1orf71', 'KBTBD8', 'KRTAP4-12', 'C21orf135',\n",
" 'KIAA0999', 'MMP10', 'C3orf50', 'LFNG', 'MMP12', 'CCL26', 'LUZP1',\n",
" 'MMP3', 'CCL3L3', 'MMP1', 'MOGAT1', 'CCRN4L', 'NFKBIA', 'MYC',\n",
" 'CD274', 'NFKBIE', 'PARP10', 'CD69', 'NPPC', 'PFKFB3', 'CD83',\n",
" 'PHLDB2', 'PLK3', 'CDKN1A', 'PTGER4', 'POLD3', 'CECR1', 'PTGS2',\n",
" 'PTPRC', 'CIB3', 'RRAD', 'SPINK1', 'CLCF1', 'SAT1', 'TMPRSS9',\n",
" 'CLK4', 'SEC24A', 'UBE1L2', 'CNNM4', 'SERPINA3', 'CREBBP',\n",
" 'SLC2A3', 'CTGF', 'SPRY2', 'CYP2E1', 'SYNE1', 'DENND2C', 'TBX3',\n",
" 'DEPDC2', 'TMCC3', 'DIRAS3', 'TNFAIP3', 'DMXL1', 'TRIB1', 'DUSP10',\n",
" 'YOD1', 'DUSP2', 'DUSP8', 'EGR1', 'ERN1', 'ERRFI1', 'FA2H', 'FGD4',\n",
" 'FOSL1', 'FOSL2', 'GADD45A', 'GATA6', 'GNB5', 'GNRH1', 'GNRHR',\n",
" 'GREM2', 'HBEGF', 'HDAC4', 'ID2', 'ID3', 'ID4', 'IL12A', 'IL3RA',\n",
" 'IL6', 'IL8', 'IRF8', 'JAG2', 'JARID2', 'JUNB', 'KCNJ14',\n",
" 'KIAA1754', 'KITLG', 'KLF10', 'KLF11', 'KLF5', 'LGI2', 'LIPG',\n",
" 'LOC341346', 'LRCH1', 'MEX3B', 'MGEA5', 'MIDN', 'MLLT1', 'MYLIP',\n",
" 'N4BP3', 'NFIL3', 'NFYA', 'NLRP3', 'NR4A1', 'NR4A2', 'NR4A3',\n",
" 'OBSCN', 'OR11H12', 'OSR1', 'PCNXL2', 'PDE4D', 'PDE4DIP', 'PDXDC2',\n",
" 'PER1', 'PIM1', 'PLA2G3', 'PPP1R14C', 'PPP1R3B', 'PRDM1', 'PTGIS',\n",
" 'PTPRE', 'RASL11B', 'RBM15', 'RBM25', 'RICTOR', 'RIPK4', 'RNF152',\n",
" 'RP13-36C9.6', 'RREB1', 'RSRC2', 'SERPINB9', 'SERTAD1', 'SETX',\n",
" 'SGK269', 'SLC19A2', 'SLC22A16', 'SLC25A25', 'SLC2A14', 'SNF1LK',\n",
" 'SOD2', 'SOX9', 'SPSB1', 'STK17B', 'TAGLN3', 'TANC2', 'TCL6',\n",
" 'TLE3', 'TNF', 'TNFSF9', 'TRAF1', 'TRIM36', 'TRIM49', 'TXNIP',\n",
" 'UBE3A', 'USP36', 'VASN', 'VNN3', 'ZC3H12A', 'ZCCHC6', 'ZFP36L2',\n",
" 'ZNF462', 'ZSCAN4'], dtype=object)"
]
},
"execution_count": 4,
"metadata": {},
"output_type": "execute_result"
}
],
"source": [
"symbols"
]
},
{
"cell_type": "code",
"execution_count": 5,
"metadata": {},
"outputs": [],
"source": [
"import mygene\n",
"mg = mygene.MyGeneInfo()\n"
]
},
{
"cell_type": "code",
"execution_count": 6,
"metadata": {},
"outputs": [
{
"name": "stdout",
"output_type": "stream",
"text": [
"querying 1-235...done.\n",
"Finished.\n",
"15 input query terms found dup hits:\n",
"\t[('ARC', 2), ('DUSP1', 2), ('DUX4', 7), ('BACH1', 2), ('GEM', 2), ('KRTAP2-4', 2), ('SAT1', 3), ('JU\n",
"4 input query terms found no hit:\n",
"\t['FLJ10404', 'KIAA0999', 'LOC341346', 'RP13-36C9.6']\n",
"Pass \"returnall=True\" to return complete lists of duplicate or missing query terms.\n"
]
}
],
"source": [
"mappings = mg.querymany(symbols, \n",
" fields='symbol,ensembl.gene',\n",
" scopes='symbol,alias', \n",
" species='human',\n",
" as_dataframe=True)\n",
"\n",
"mappings['notfound'] = mappings['notfound'].fillna(False)"
]
},
{
"cell_type": "code",
"execution_count": 7,
"metadata": {},
"outputs": [],
"source": [
"# deduplicate by taking the best scoring result\n",
"mappings = mappings.groupby(mappings.index).apply(lambda x: x.sort_values(by='_score', ascending=False).iloc[0])"
]
},
{
"cell_type": "code",
"execution_count": 8,
"metadata": {},
"outputs": [],
"source": [
"mappings_processed = []\n",
"\n",
"for ix, row in mappings.iterrows():\n",
" ensembl = row['ensembl']\n",
" ensembl_gene = row['ensembl.gene']\n",
"\n",
" if not isinstance(ensembl, list) and pd.isnull(ensembl):\n",
" mappings_processed.append(row)\n",
" else:\n",
" \n",
" new_row = row.copy()\n",
" if not pd.isnull(ensembl_gene):\n",
" raise Exception(f'Both non null for {ix}')\n",
" \n",
" gene_ids = set()\n",
" for annot in ensembl:\n",
" gene_ids.add(annot['gene'])\n",
" \n",
" new_row['ensembl.gene'] = '/'.join(sorted(gene_ids))\n",
" new_row['ensembl'] = None\n",
" \n",
" mappings_processed.append(new_row)\n",
"\n",
"mappings_processed = pd.DataFrame(mappings_processed, index=mappings.index)\n",
"\n",
"del mappings_processed['ensembl']\n"
]
},
{
"cell_type": "code",
"execution_count": 9,
"metadata": {},
"outputs": [],
"source": [
"# Mygene.info gets most but this is some extra\n",
"MANUAL_MAPPINGS = {\n",
" 'C1orf79': 'ENSG00000197989',\n",
" 'C21orf135': 'ENSG00000261706',\n",
" 'C3orf50': 'ENSG00000206120',\n",
" 'FLJ10404': 'ENSG00000146067',\n",
" 'KCNQ10T1': 'ENSG00000269821',\n",
" 'KIAA0999': 'ENSG00000160584',\n",
" 'LOC341346': 'ENSG00000165935',\n",
" 'PDXDC2': 'ENSG00000255185',\n",
" 'RP13-36C9.6': 'ENSG00000228836',\n",
"}\n",
"\n"
]
},
{
"cell_type": "code",
"execution_count": 10,
"metadata": {},
"outputs": [],
"source": [
"for ix, ensembl_gene in MANUAL_MAPPINGS.items():\n",
" \n",
" current_gene = mappings_processed.loc[ix, 'ensembl.gene']\n",
" \n",
" if not pd.isnull(current_gene) and current_gene != ensembl_gene:\n",
" raise Exception(f'Trying to assing {ensembl_gene} to {ix} but it already has {current_gene} assigned')\n",
" \n",
" mappings_processed.loc[ix, 'ensembl.gene'] = ensembl_gene"
]
},
{
"cell_type": "code",
"execution_count": 11,
"metadata": {},
"outputs": [
{
"data": {
"text/html": [
"<div>\n",
"<style scoped>\n",
" .dataframe tbody tr th:only-of-type {\n",
" vertical-align: middle;\n",
" }\n",
"\n",
" .dataframe tbody tr th {\n",
" vertical-align: top;\n",
" }\n",
"\n",
" .dataframe thead th {\n",
" text-align: right;\n",
" }\n",
"</style>\n",
"<table border=\"1\" class=\"dataframe\">\n",
" <thead>\n",
" <tr style=\"text-align: right;\">\n",
" <th></th>\n",
" <th>_id</th>\n",
" <th>_score</th>\n",
" <th>symbol</th>\n",
" <th>ensembl.gene</th>\n",
" <th>notfound</th>\n",
" </tr>\n",
" <tr>\n",
" <th>query</th>\n",
" <th></th>\n",
" <th></th>\n",
" <th></th>\n",
" <th></th>\n",
" <th></th>\n",
" </tr>\n",
" </thead>\n",
" <tbody>\n",
" </tbody>\n",
"</table>\n",
"</div>"
],
"text/plain": [
"Empty DataFrame\n",
"Columns: [_id, _score, symbol, ensembl.gene, notfound]\n",
"Index: []"
]
},
"execution_count": 11,
"metadata": {},
"output_type": "execute_result"
}
],
"source": [
"mappings_processed[mappings_processed['ensembl.gene'].isnull()]"
]
},
{
"cell_type": "code",
"execution_count": 12,
"metadata": {},
"outputs": [
{
"data": {
"text/html": [
"<div>\n",
"<style scoped>\n",
" .dataframe tbody tr th:only-of-type {\n",
" vertical-align: middle;\n",
" }\n",
"\n",
" .dataframe tbody tr th {\n",
" vertical-align: top;\n",
" }\n",
"\n",
" .dataframe thead th {\n",
" text-align: right;\n",
" }\n",
"</style>\n",
"<table border=\"1\" class=\"dataframe\">\n",
" <thead>\n",
" <tr style=\"text-align: right;\">\n",
" <th></th>\n",
" <th>_id</th>\n",
" <th>_score</th>\n",
" <th>symbol</th>\n",
" <th>ensembl.gene</th>\n",
" <th>notfound</th>\n",
" </tr>\n",
" <tr>\n",
" <th>query</th>\n",
" <th></th>\n",
" <th></th>\n",
" <th></th>\n",
" <th></th>\n",
" <th></th>\n",
" </tr>\n",
" </thead>\n",
" <tbody>\n",
" <tr>\n",
" <th>ABL2</th>\n",
" <td>27</td>\n",
" <td>85.996160</td>\n",
" <td>ABL2</td>\n",
" <td>ENSG00000143322</td>\n",
" <td>False</td>\n",
" </tr>\n",
" <tr>\n",
" <th>ADAMTS15</th>\n",
" <td>170689</td>\n",
" <td>88.832230</td>\n",
" <td>ADAMTS15</td>\n",
" <td>ENSG00000166106</td>\n",
" <td>False</td>\n",
" </tr>\n",
" <tr>\n",
" <th>ADRA1B</th>\n",
" <td>147</td>\n",
" <td>88.841980</td>\n",
" <td>ADRA1B</td>\n",
" <td>ENSG00000170214</td>\n",
" <td>False</td>\n",
" </tr>\n",
" <tr>\n",
" <th>ALS2</th>\n",
" <td>57679</td>\n",
" <td>87.331290</td>\n",
" <td>ALS2</td>\n",
" <td>ENSG00000003393</td>\n",
" <td>False</td>\n",
" </tr>\n",
" <tr>\n",
" <th>ANGPT1</th>\n",
" <td>284</td>\n",
" <td>87.895485</td>\n",
" <td>ANGPT1</td>\n",
" <td>ENSG00000154188</td>\n",
" <td>False</td>\n",
" </tr>\n",
" </tbody>\n",
"</table>\n",
"</div>"
],
"text/plain": [
" _id _score symbol ensembl.gene notfound\n",
"query \n",
"ABL2 27 85.996160 ABL2 ENSG00000143322 False\n",
"ADAMTS15 170689 88.832230 ADAMTS15 ENSG00000166106 False\n",
"ADRA1B 147 88.841980 ADRA1B ENSG00000170214 False\n",
"ALS2 57679 87.331290 ALS2 ENSG00000003393 False\n",
"ANGPT1 284 87.895485 ANGPT1 ENSG00000154188 False"
]
},
"execution_count": 12,
"metadata": {},
"output_type": "execute_result"
}
],
"source": [
"mappings_processed.head()"
]
},
{
"cell_type": "code",
"execution_count": 13,
"metadata": {},
"outputs": [],
"source": [
"mappings_processed = mappings_processed[['symbol', 'ensembl.gene']]\n",
"mappings_processed = mappings_processed.rename(columns={\n",
" 'symbol': 'updated_symbol',\n",
" 'ensembl.gene': 'ensembl_gene_id'\n",
"})\n",
"\n",
"mappings_processed.index.name = 'stoltzman_symbol'"
]
},
{
"cell_type": "code",
"execution_count": 14,
"metadata": {},
"outputs": [],
"source": [
"long_data = data.stack().reset_index()\n",
"del long_data['level_0']\n",
"\n",
"long_data.columns = ['stoltzman_classification', 'stoltzman_symbol']\n",
"long_data = long_data.join(mappings_processed, on='stoltzman_symbol')\n",
"long_data = long_data.sort_values(by=['stoltzman_classification', 'stoltzman_symbol'])"
]
},
{
"cell_type": "code",
"execution_count": 15,
"metadata": {},
"outputs": [],
"source": [
"long_data.to_csv('figure-s1-processed.tsv',\n",
" index=False,\n",
" sep='\\t')"
]
},
{
"cell_type": "code",
"execution_count": 16,
"metadata": {},
"outputs": [
{
"name": "stdout",
"output_type": "stream",
"text": [
"stoltzman_classification\tstoltzman_symbol\tupdated_symbol\tensembl_gene_id\r\n",
"Compensation\tANGPTL4\tANGPTL4\tENSG00000167772\r\n",
"Compensation\tBBC3\tBBC3\tENSG00000105327\r\n",
"Compensation\tBMP8A\tBMP8A\tENSG00000183682\r\n",
"Compensation\tC10orf137\tEDRF1\tENSG00000107938\r\n",
"Compensation\tCNOT2\tCNOT2\tENSG00000111596\r\n",
"Compensation\tCXCL14\tCXCL14\tENSG00000145824\r\n",
"Compensation\tCYR61\tCCN1\tENSG00000142871\r\n",
"Compensation\tDEFB103B\tDEFB103B\tENSG00000177243/ENSG00000273641\r\n",
"Compensation\tDGCR8\tDGCR8\tENSG00000128191\r\n"
]
}
],
"source": [
"!head figure-s1-processed.tsv"
]
},
{
"cell_type": "code",
"execution_count": 17,
"metadata": {},
"outputs": [
{
"name": "stdout",
"output_type": "stream",
"text": [
"3.1.0\n"
]
}
],
"source": [
"print(mygene.__version__)"
]
},
{
"cell_type": "code",
"execution_count": null,
"metadata": {},
"outputs": [],
"source": []
},
{
"cell_type": "code",
"execution_count": null,
"metadata": {},
"outputs": [],
"source": []
}
],
"metadata": {
"kernelspec": {
"display_name": "Python 3",
"language": "python",
"name": "python3"
},
"language_info": {
"codemirror_mode": {
"name": "ipython",
"version": 3
},
"file_extension": ".py",
"mimetype": "text/x-python",
"name": "python",
"nbconvert_exporter": "python",
"pygments_lexer": "ipython3",
"version": "3.7.5"
}
},
"nbformat": 4,
"nbformat_minor": 4
}
stoltzman_classification stoltzman_symbol updated_symbol ensembl_gene_id
Compensation ANGPTL4 ANGPTL4 ENSG00000167772
Compensation BBC3 BBC3 ENSG00000105327
Compensation BMP8A BMP8A ENSG00000183682
Compensation C10orf137 EDRF1 ENSG00000107938
Compensation CNOT2 CNOT2 ENSG00000111596
Compensation CXCL14 CXCL14 ENSG00000145824
Compensation CYR61 CCN1 ENSG00000142871
Compensation DEFB103B DEFB103B ENSG00000177243/ENSG00000273641
Compensation DGCR8 DGCR8 ENSG00000128191
Compensation DRD4 DRD4 ENSG00000069696/ENSG00000276825
Compensation DUSP1 DUSP1 ENSG00000120129
Compensation DUX4 DUX4 ENSG00000260596/ENSG00000283949
Compensation ETS2 ETS2 ENSG00000157557
Compensation FLJ10404 ENSG00000146067
Compensation FTMT FTMT ENSG00000181867
Compensation GLI4 GLI4 ENSG00000250571
Compensation GSX2 GSX2 ENSG00000180613
Compensation HCN2 HCN2 ENSG00000099822
Compensation HNRPDL HNRNPDL ENSG00000152795
Compensation HS2ST1 HS2ST1 ENSG00000153936
Compensation INSIG1 INSIG1 ENSG00000186480
Compensation KCNQ10T1 KCNQ1OT1 ENSG00000269821
Compensation KRTAP2-4 KRTAP2-4 ENSG00000213417/ENSG00000263091
Compensation KRTAP4-12 KRTAP4-12 ENSG00000213416/ENSG00000263236
Compensation MMP10 MMP10 ENSG00000166670
Compensation MMP12 MMP12 ENSG00000262406
Compensation MMP3 MMP3 ENSG00000149968
Compensation MOGAT1 MOGAT1 ENSG00000124003
Compensation MYC MYC ENSG00000136997
Compensation PARP10 PARP10 ENSG00000178685
Compensation PFKFB3 PFKFB3 ENSG00000170525
Compensation PLK3 PLK3 ENSG00000173846
Compensation POLD3 POLD3 ENSG00000077514
Compensation PTPRC PTPRC ENSG00000081237/ENSG00000262418
Compensation SPINK1 SPINK1 ENSG00000164266
Compensation TMPRSS9 TMPRSS9 ENSG00000178297
Compensation UBE1L2 UBA6 ENSG00000033178
DG-Dependent/MondoA independent ABL2 ABL2 ENSG00000143322
DG-Dependent/MondoA independent ANKRD1 ANKRD1 ENSG00000148677
DG-Dependent/MondoA independent C1orf79 SNHG12 ENSG00000197989
DG-Dependent/MondoA independent C3orf52 C3orf52 ENSG00000114529/ENSG00000285394
DG-Dependent/MondoA independent CCL3 CCL3 ENSG00000274221/ENSG00000277632/ENSG00000278567
DG-Dependent/MondoA independent CRYAB CRYAB ENSG00000109846
DG-Dependent/MondoA independent CSF2 CSF2 ENSG00000164400
DG-Dependent/MondoA independent DST DST ENSG00000151914
DG-Dependent/MondoA independent DUSP6 DUSP6 ENSG00000139318
DG-Dependent/MondoA independent EBI2 GPR183 ENSG00000169508
DG-Dependent/MondoA independent EDN1 EDN1 ENSG00000078401
DG-Dependent/MondoA independent EPC1 EPC1 ENSG00000120616
DG-Dependent/MondoA independent EYA3 EYA3 ENSG00000158161
DG-Dependent/MondoA independent FAM46C TENT5C ENSG00000183508
DG-Dependent/MondoA independent FBN2 FBN2 ENSG00000138829
DG-Dependent/MondoA independent FGFR3 FGFR3 ENSG00000068078
DG-Dependent/MondoA independent GEM GEM ENSG00000164949
DG-Dependent/MondoA independent GNPTAB GNPTAB ENSG00000111670
DG-Dependent/MondoA independent GRASP TAMALIN ENSG00000161835
DG-Dependent/MondoA independent ID1 ID1 ENSG00000125968
DG-Dependent/MondoA independent IER3 IER3 ENSG00000137331/ENSG00000206478/ENSG00000227231/ENSG00000230128/ENSG00000235030/ENSG00000237155
DG-Dependent/MondoA independent IL11 IL11 ENSG00000095752
DG-Dependent/MondoA independent IL1RL1 IL1RL1 ENSG00000115602
DG-Dependent/MondoA independent KBTBD8 KBTBD8 ENSG00000163376
DG-Dependent/MondoA independent KIAA0999 ENSG00000160584
DG-Dependent/MondoA independent LFNG LFNG ENSG00000106003
DG-Dependent/MondoA independent LUZP1 LUZP1 ENSG00000169641
DG-Dependent/MondoA independent MMP1 MMP1 ENSG00000196611
DG-Dependent/MondoA independent NFKBIA NFKBIA ENSG00000100906
DG-Dependent/MondoA independent NFKBIE NFKBIE ENSG00000146232
DG-Dependent/MondoA independent NPPC NPPC ENSG00000163273
DG-Dependent/MondoA independent PHLDB2 PHLDB2 ENSG00000144824
DG-Dependent/MondoA independent PTGER4 PTGER4 ENSG00000171522
DG-Dependent/MondoA independent PTGS2 PTGS2 ENSG00000073756
DG-Dependent/MondoA independent RRAD RRAD ENSG00000166592
DG-Dependent/MondoA independent SAT1 SAT1 ENSG00000130066
DG-Dependent/MondoA independent SEC24A SEC24A ENSG00000113615
DG-Dependent/MondoA independent SERPINA3 SERPINA3 ENSG00000196136
DG-Dependent/MondoA independent SLC2A3 SLC2A3 ENSG00000059804
DG-Dependent/MondoA independent SPRY2 SPRY2 ENSG00000136158
DG-Dependent/MondoA independent SYNE1 SYNE1 ENSG00000131018
DG-Dependent/MondoA independent TBX3 TBX3 ENSG00000135111
DG-Dependent/MondoA independent TMCC3 TMCC3 ENSG00000057704
DG-Dependent/MondoA independent TNFAIP3 TNFAIP3 ENSG00000118503
DG-Dependent/MondoA independent TRIB1 TRIB1 ENSG00000173334
DG-Dependent/MondoA independent YOD1 YOD1 ENSG00000180667
DG-dependent/MondoA-dependent ADAMTS15 ADAMTS15 ENSG00000166106
DG-dependent/MondoA-dependent ADRA1B ADRA1B ENSG00000170214
DG-dependent/MondoA-dependent ALS2 ALS2 ENSG00000003393
DG-dependent/MondoA-dependent ANGPT1 ANGPT1 ENSG00000154188
DG-dependent/MondoA-dependent AQP10 AQP10 ENSG00000143595
DG-dependent/MondoA-dependent ARC ARC ENSG00000198576
DG-dependent/MondoA-dependent ARHGAP6 ARHGAP6 ENSG00000047648
DG-dependent/MondoA-dependent ARHGEF3 ARHGEF3 ENSG00000163947
DG-dependent/MondoA-dependent ARID3B ARID3B ENSG00000179361
DG-dependent/MondoA-dependent ARID5B ARID5B ENSG00000150347
DG-dependent/MondoA-dependent ARRDC4 ARRDC4 ENSG00000140450
DG-dependent/MondoA-dependent AVPI1 AVPI1 ENSG00000119986
DG-dependent/MondoA-dependent AXUD1 CSRNP1 ENSG00000144655
DG-dependent/MondoA-dependent BACH1 BACH1 ENSG00000156273
DG-dependent/MondoA-dependent BAMBI BAMBI ENSG00000095739
DG-dependent/MondoA-dependent BCL2A1 BCL2A1 ENSG00000140379
DG-dependent/MondoA-dependent BCL6 BCL6 ENSG00000113916
DG-dependent/MondoA-dependent BHLHB2 BHLHE40 ENSG00000134107
DG-dependent/MondoA-dependent BIRC3 BIRC3 ENSG00000023445
DG-dependent/MondoA-dependent C11orf17 AKIP1 ENSG00000166452
DG-dependent/MondoA-dependent C12orf42 C12orf42 ENSG00000179088
DG-dependent/MondoA-dependent C13orf15 RGCC ENSG00000102760
DG-dependent/MondoA-dependent C1orf63 RSRP1 ENSG00000117616
DG-dependent/MondoA-dependent C1orf71 CNST ENSG00000162852
DG-dependent/MondoA-dependent C21orf135 LINC00165 ENSG00000261706
DG-dependent/MondoA-dependent C3orf50 EGFEM1P ENSG00000206120
DG-dependent/MondoA-dependent CCL26 CCL26 ENSG00000006606
DG-dependent/MondoA-dependent CCL3L3 CCL3L3 ENSG00000276085
DG-dependent/MondoA-dependent CCRN4L NOCT ENSG00000151014
DG-dependent/MondoA-dependent CD274 CD274 ENSG00000120217
DG-dependent/MondoA-dependent CD69 CD69 ENSG00000110848
DG-dependent/MondoA-dependent CD83 CD83 ENSG00000112149
DG-dependent/MondoA-dependent CDKN1A CDKN1A ENSG00000124762
DG-dependent/MondoA-dependent CECR1 ADA2 ENSG00000093072
DG-dependent/MondoA-dependent CIB3 CIB3 ENSG00000141977
DG-dependent/MondoA-dependent CLCF1 CLCF1 ENSG00000175505
DG-dependent/MondoA-dependent CLK4 CLK4 ENSG00000113240
DG-dependent/MondoA-dependent CNNM4 CNNM4 ENSG00000158158
DG-dependent/MondoA-dependent CREBBP CREBBP ENSG00000005339
DG-dependent/MondoA-dependent CTGF CCN2 ENSG00000118523
DG-dependent/MondoA-dependent CYP2E1 CYP2E1 ENSG00000130649
DG-dependent/MondoA-dependent DENND2C DENND2C ENSG00000175984
DG-dependent/MondoA-dependent DEPDC2 PREX2 ENSG00000046889
DG-dependent/MondoA-dependent DIRAS3 DIRAS3 ENSG00000162595
DG-dependent/MondoA-dependent DMXL1 DMXL1 ENSG00000172869
DG-dependent/MondoA-dependent DUSP10 DUSP10 ENSG00000143507
DG-dependent/MondoA-dependent DUSP2 DUSP2 ENSG00000158050
DG-dependent/MondoA-dependent DUSP8 DUSP8 ENSG00000184545/ENSG00000273793/ENSG00000278165
DG-dependent/MondoA-dependent EGR1 EGR1 ENSG00000120738
DG-dependent/MondoA-dependent ERN1 ERN1 ENSG00000178607
DG-dependent/MondoA-dependent ERRFI1 ERRFI1 ENSG00000116285
DG-dependent/MondoA-dependent FA2H FA2H ENSG00000103089
DG-dependent/MondoA-dependent FGD4 FGD4 ENSG00000139132
DG-dependent/MondoA-dependent FOSL1 FOSL1 ENSG00000175592
DG-dependent/MondoA-dependent FOSL2 FOSL2 ENSG00000075426
DG-dependent/MondoA-dependent GADD45A GADD45A ENSG00000116717
DG-dependent/MondoA-dependent GATA6 GATA6 ENSG00000141448
DG-dependent/MondoA-dependent GNB5 GNB5 ENSG00000069966
DG-dependent/MondoA-dependent GNRH1 GNRH1 ENSG00000147437
DG-dependent/MondoA-dependent GNRHR GNRHR ENSG00000109163
DG-dependent/MondoA-dependent GREM2 GREM2 ENSG00000180875
DG-dependent/MondoA-dependent HBEGF HBEGF ENSG00000113070
DG-dependent/MondoA-dependent HDAC4 HDAC4 ENSG00000068024
DG-dependent/MondoA-dependent ID2 ID2 ENSG00000115738
DG-dependent/MondoA-dependent ID3 ID3 ENSG00000117318/ENSG00000283060
DG-dependent/MondoA-dependent ID4 ID4 ENSG00000172201
DG-dependent/MondoA-dependent IL12A IL12A ENSG00000168811
DG-dependent/MondoA-dependent IL3RA IL3RA ENSG00000185291
DG-dependent/MondoA-dependent IL6 IL6 ENSG00000136244
DG-dependent/MondoA-dependent IL8 CXCL8 ENSG00000169429
DG-dependent/MondoA-dependent IRF8 IRF8 ENSG00000140968
DG-dependent/MondoA-dependent JAG2 JAG2 ENSG00000184916
DG-dependent/MondoA-dependent JARID2 JARID2 ENSG00000008083
DG-dependent/MondoA-dependent JUNB JUNB ENSG00000171223
DG-dependent/MondoA-dependent KCNJ14 KCNJ14 ENSG00000182324
DG-dependent/MondoA-dependent KIAA1754 ITPRIP ENSG00000148841
DG-dependent/MondoA-dependent KITLG KITLG ENSG00000049130
DG-dependent/MondoA-dependent KLF10 KLF10 ENSG00000155090
DG-dependent/MondoA-dependent KLF11 KLF11 ENSG00000172059
DG-dependent/MondoA-dependent KLF5 KLF5 ENSG00000102554
DG-dependent/MondoA-dependent LGI2 LGI2 ENSG00000153012
DG-dependent/MondoA-dependent LIPG LIPG ENSG00000101670
DG-dependent/MondoA-dependent LOC341346 ENSG00000165935
DG-dependent/MondoA-dependent LRCH1 LRCH1 ENSG00000136141
DG-dependent/MondoA-dependent MEX3B MEX3B ENSG00000183496
DG-dependent/MondoA-dependent MGEA5 OGA ENSG00000198408
DG-dependent/MondoA-dependent MIDN MIDN ENSG00000167470
DG-dependent/MondoA-dependent MLLT1 MLLT1 ENSG00000130382
DG-dependent/MondoA-dependent MYLIP MYLIP ENSG00000007944
DG-dependent/MondoA-dependent N4BP3 N4BP3 ENSG00000145911
DG-dependent/MondoA-dependent NFIL3 NFIL3 ENSG00000165030
DG-dependent/MondoA-dependent NFYA NFYA ENSG00000001167
DG-dependent/MondoA-dependent NLRP3 NLRP3 ENSG00000162711
DG-dependent/MondoA-dependent NR4A1 NR4A1 ENSG00000123358
DG-dependent/MondoA-dependent NR4A2 NR4A2 ENSG00000153234
DG-dependent/MondoA-dependent NR4A3 NR4A3 ENSG00000119508
DG-dependent/MondoA-dependent OBSCN OBSCN ENSG00000154358
DG-dependent/MondoA-dependent OR11H12 OR11H12 ENSG00000257115
DG-dependent/MondoA-dependent OSR1 OSR1 ENSG00000143867
DG-dependent/MondoA-dependent PCNXL2 PCNX2 ENSG00000135749
DG-dependent/MondoA-dependent PDE4D PDE4D ENSG00000113448
DG-dependent/MondoA-dependent PDE4DIP PDE4DIP ENSG00000178104
DG-dependent/MondoA-dependent PDXDC2 PDXDC2P ENSG00000255185
DG-dependent/MondoA-dependent PER1 PER1 ENSG00000179094
DG-dependent/MondoA-dependent PIM1 PIM1 ENSG00000137193
DG-dependent/MondoA-dependent PLA2G3 PLA2G3 ENSG00000100078
DG-dependent/MondoA-dependent PPP1R14C PPP1R14C ENSG00000198729
DG-dependent/MondoA-dependent PPP1R3B PPP1R3B ENSG00000173281/ENSG00000285343
DG-dependent/MondoA-dependent PRDM1 PRDM1 ENSG00000057657
DG-dependent/MondoA-dependent PTGIS PTGIS ENSG00000124212
DG-dependent/MondoA-dependent PTPRE PTPRE ENSG00000132334
DG-dependent/MondoA-dependent RASL11B RASL11B ENSG00000128045
DG-dependent/MondoA-dependent RBM15 RBM15 ENSG00000162775
DG-dependent/MondoA-dependent RBM25 RBM25 ENSG00000119707
DG-dependent/MondoA-dependent RICTOR RICTOR ENSG00000164327
DG-dependent/MondoA-dependent RIPK4 RIPK4 ENSG00000183421
DG-dependent/MondoA-dependent RNF152 RNF152 ENSG00000176641
DG-dependent/MondoA-dependent RP13-36C9.6 ENSG00000228836
DG-dependent/MondoA-dependent RREB1 RREB1 ENSG00000124782
DG-dependent/MondoA-dependent RSRC2 RSRC2 ENSG00000111011
DG-dependent/MondoA-dependent SERPINB9 SERPINB9 ENSG00000170542
DG-dependent/MondoA-dependent SERTAD1 SERTAD1 ENSG00000197019
DG-dependent/MondoA-dependent SETX SETX ENSG00000107290
DG-dependent/MondoA-dependent SGK269 PEAK1 ENSG00000173517
DG-dependent/MondoA-dependent SLC19A2 SLC19A2 ENSG00000117479
DG-dependent/MondoA-dependent SLC22A16 SLC22A16 ENSG00000004809
DG-dependent/MondoA-dependent SLC25A25 SLC25A25 ENSG00000148339
DG-dependent/MondoA-dependent SLC2A14 SLC2A14 ENSG00000173262
DG-dependent/MondoA-dependent SNF1LK SIK1 ENSG00000142178
DG-dependent/MondoA-dependent SOD2 SOD2 ENSG00000112096/ENSG00000285441
DG-dependent/MondoA-dependent SOX9 SOX9 ENSG00000125398
DG-dependent/MondoA-dependent SPSB1 SPSB1 ENSG00000171621
DG-dependent/MondoA-dependent STK17B STK17B ENSG00000081320
DG-dependent/MondoA-dependent TAGLN3 TAGLN3 ENSG00000144834
DG-dependent/MondoA-dependent TANC2 TANC2 ENSG00000170921
DG-dependent/MondoA-dependent TCL6 TCL6 ENSG00000187621
DG-dependent/MondoA-dependent TLE3 TLE3 ENSG00000140332
DG-dependent/MondoA-dependent TNF TNF ENSG00000204490/ENSG00000206439/ENSG00000223952/ENSG00000228321/ENSG00000228849/ENSG00000228978/ENSG00000230108/ENSG00000232810
DG-dependent/MondoA-dependent TNFSF9 TNFSF9 ENSG00000125657
DG-dependent/MondoA-dependent TRAF1 TRAF1 ENSG00000056558
DG-dependent/MondoA-dependent TRIM36 TRIM36 ENSG00000152503
DG-dependent/MondoA-dependent TRIM49 TRIM49 ENSG00000168930
DG-dependent/MondoA-dependent TXNIP TXNIP ENSG00000265972
DG-dependent/MondoA-dependent UBE3A UBE3A ENSG00000114062
DG-dependent/MondoA-dependent USP36 USP36 ENSG00000055483
DG-dependent/MondoA-dependent VASN VASN ENSG00000168140/ENSG00000274334
DG-dependent/MondoA-dependent VNN3 VNN3 ENSG00000093134
DG-dependent/MondoA-dependent ZC3H12A ZC3H12A ENSG00000163874
DG-dependent/MondoA-dependent ZCCHC6 TUT7 ENSG00000083223
DG-dependent/MondoA-dependent ZFP36L2 ZFP36L2 ENSG00000152518
DG-dependent/MondoA-dependent ZNF462 ZNF462 ENSG00000148143
DG-dependent/MondoA-dependent ZSCAN4 ZSCAN4 ENSG00000180532
DG-dependent/MondoA-dependent DG-Dependent/MondoA independent Compensation
ADAMTS15 ABL2 ANGPTL4
ADRA1B ANKRD1 BBC3
ALS2 C1orf79 BMP8A
ANGPT1 C3orf52 C10orf137
AQP10 CCL3 CNOT2
ARC CRYAB CXCL14
ARHGAP6 CSF2 CYR61
ARHGEF3 DST DEFB103B
ARID3B DUSP6 DGCR8
ARID5B EBI2 DRD4
ARRDC4 EDN1 DUSP1
AVPI1 EPC1 DUX4
AXUD1 EYA3 ETS2
BACH1 FAM46C FLJ10404
BAMBI FBN2 FTMT
BCL2A1 FGFR3 GLI4
BCL6 GEM GSX2
BHLHB2 GNPTAB HCN2
BIRC3 GRASP HNRPDL
C11orf17 ID1 HS2ST1
C12orf42 IER3 INSIG1
C13orf15 IL11 KCNQ10T1
C1orf63 IL1RL1 KRTAP2-4
C1orf71 KBTBD8 KRTAP4-12
C21orf135 KIAA0999 MMP10
C3orf50 LFNG MMP12
CCL26 LUZP1 MMP3
CCL3L3 MMP1 MOGAT1
CCRN4L NFKBIA MYC
CD274 NFKBIE PARP10
CD69 NPPC PFKFB3
CD83 PHLDB2 PLK3
CDKN1A PTGER4 POLD3
CECR1 PTGS2 PTPRC
CIB3 RRAD SPINK1
CLCF1 SAT1 TMPRSS9
CLK4 SEC24A UBE1L2
CNNM4 SERPINA3
CREBBP SLC2A3
CTGF SPRY2
CYP2E1 SYNE1
DENND2C TBX3
DEPDC2 TMCC3
DIRAS3 TNFAIP3
DMXL1 TRIB1
DUSP10 YOD1
DUSP2
DUSP8
EGR1
ERN1
ERRFI1
FA2H
FGD4
FOSL1
FOSL2
GADD45A
GATA6
GNB5
GNRH1
GNRHR
GREM2
HBEGF
HDAC4
ID2
ID3
ID4
IL12A
IL3RA
IL6
IL8
IRF8
JAG2
JARID2
JUNB
KCNJ14
KIAA1754
KITLG
KLF10
KLF11
KLF5
LGI2
LIPG
LOC341346
LRCH1
MEX3B
MGEA5
MIDN
MLLT1
MYLIP
N4BP3
NFIL3
NFYA
NLRP3
NR4A1
NR4A2
NR4A3
OBSCN
OR11H12
OSR1
PCNXL2
PDE4D
PDE4DIP
PDXDC2
PER1
PIM1
PLA2G3
PPP1R14C
PPP1R3B
PRDM1
PTGIS
PTPRE
RASL11B
RBM15
RBM25
RICTOR
RIPK4
RNF152
RP13-36C9.6
RREB1
RSRC2
SERPINB9
SERTAD1
SETX
SGK269
SLC19A2
SLC22A16
SLC25A25
SLC2A14
SNF1LK
SOD2
SOX9
SPSB1
STK17B
TAGLN3
TANC2
TCL6
TLE3
TNF
TNFSF9
TRAF1
TRIM36
TRIM49
TXNIP
UBE3A
USP36
VASN
VNN3
ZC3H12A
ZCCHC6
ZFP36L2
ZNF462
ZSCAN4
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