Sublime REPL settings for Anaconda distribution of Python. Included are REPL settings for python and ipython running under python 2.7 and python 3.3. Be sure to provide the appropriate path to your Anaconda Python 2.7 and Python 3.3 executables within the lines that start with "cmd" .

Main.sublime-menu

[
{
        "id": "tools",
        "children":
        [{
            "caption": "SublimeREPL",
            "mnemonic": "r",
            "id": "SublimeREPL",
            "children":
            [
                {
                    "caption": "Python",
                    "id": "Python",

                    "children":[
                        {
                            "command": "repl_open",
                            "caption": "Python 2.7 - Anaconda",
                            "id": "repl_python",
                            "mnemonic": "p",
                            "args": {
                                "type": "subprocess",
                                "encoding": "utf8",
                                "cmd": ["/anaconda/bin/python2.7", "-i", "-u"],
                                "cwd": "$file_path",
                                "syntax": "Packages/Python/Python.tmLanguage",
                                "external_id": "python",
                                "extend_env": {"PYTHONIOENCODING": "utf-8"}
                            }
                        },
                              {
                            "command": "repl_open",
                            "caption": "Python 3.3 - Anaconda",
                            "id": "repl_python",
                            "mnemonic": "p",
                            "args": {
                                "type": "subprocess",
                                "encoding": "utf8",
                                "cmd": ["/anaconda/envs/py3k/bin/python3.3", "-i", "-u"],
                                "cwd": "$file_path",
                                "syntax": "Packages/Python/Python.tmLanguage",
                                "external_id": "python",
                                "extend_env": {"PYTHONIOENCODING": "utf-8"}
                            }
                        },
                        {
                            "command": "repl_open",
                            "caption": "IPython 2.7 - Anaconda",
                            "id": "repl_python_ipython",
                            "mnemonic": "p",
                            "args": {
                                "type": "subprocess",
                                "encoding": "utf8",
                                "autocomplete_server": true,
                                "cmd": ["/anaconda/bin/python2.7", "-u", "${packages}/SublimeREPL/config/Python/ipy_repl.py"],
                                "cwd": "$file_path",
                                "syntax": "Packages/Python/Python.tmLanguage",
                                "external_id": "python",
                                "extend_env": {
                                    "PYTHONIOENCODING": "utf-8",
                                    "SUBLIMEREPL_EDITOR": "$editor"
                                }
                            }
                        },
                          {
                            "command": "repl_open",
                            "caption": "IPython 3.3 - Anaconda",
                            "id": "repl_python_ipython",
                            "mnemonic": "p",
                            "args": {
                                "type": "subprocess",
                                "encoding": "utf8",
                                "autocomplete_server": true,
                                "cmd": ["/anaconda/envs/py3k/bin/python3.3", "-u", "${packages}/SublimeREPL/config/Python/ipy_repl.py"],
                                "cwd": "$file_path",
                                "syntax": "Packages/Python/Python.tmLanguage",
                                "external_id": "python",
                                "extend_env": {
                                    "PYTHONIOENCODING": "utf-8",
                                    "SUBLIMEREPL_EDITOR": "$editor"
                                }
                            }
                        }

                    ]
                }
            ]
        }]
    }
    ]

Go to your ST3 packages directory and inside create a folder titled User, then inside of this folder, create the directory of folders as follows: SublimeREPL>config>Python. Inside of the Python folder create a text file with the contents of this gist and name it Main.sublime-menu.

Excellent gist, thank you very much

Hi, I did all as you mentioned. Either way, I am getting the following error when trying to run python3 from sublime repl

PermissionError(13, 'Permission denied')

Hi amarting,

If you are on Windows then you need to change the path to your Python executable to something like this:
"cmd": ["C:/Anaconda/python.exe", "-i", "-u"],