IsEnabled binding of a user control

gistfile1.txt

Instead of modifying a binding in some way (for example you can make it dependent on other control name as it is proposed in other answer) I would move separate the control which will be disabled and control where DataContext will be changed. For example:

<ContentControl IsEnabled="{Binding CanModify}" Grid.Row="1" Grid.Column="0" Grid.ColumnSpan="2">
    <localControls:TeamEmployeeSelector DataContext="{Binding Confidentiality}"/>
</ContentControl>

From http://stackoverflow.com/a/5444979/1260257