gistfile1.py

class FileReader:
    def __init__(self, fp):
        self.fp = fp
    def read_callback(self, size):
        return self.fp.read(size)

def curl_upload(f, u):
    c = pycurl.Curl()
    c.setopt(pycurl.URL, u)
    c.setopt(pycurl.UPLOAD, 1)
    c.setopt(pycurl.READFUNCTION, FileReader(open(f, 'rb')).read_callback)
    filesize = os.path.getsize(f)
    c.setopt(pycurl.INFILESIZE, filesize)
    c.perform()
    status = c.getinfo(pycurl.HTTP_CODE)
    c.close()
    return status