Simple setup.py that also checks if cython exists or not. Also allows for extra .c files.

setup.py

sources = [
    ("test1.pyx", []),
    ("test2.pyx", ["extra.c"])
]

import os
import sys

def main():
    if cython_exists():
        cythonize_paths()
    compile_c()

def cythonize_paths():
    pyx_sources = [source[0] for source in sources]

    from Cython.Build import cythonize
    for path in pyx_sources:
        cythonize(path)

def cython_exists():
    try:
        import Cython
        return True
    except:
        return False

def compile_c():
    c_source_groups = {}
    for source in sources:
        module_name = get_file_name_without_extension(source[0])
        source_files = [change_file_extension(source[0], ".c")] + source[1]
        c_source_groups[module_name] = source_files

    from distutils.core import Extension
    for module_name, c_file_paths in c_source_groups.items():
        extension = Extension(module_name, sources = c_file_paths)
        compile_extension(extension)

def compile_extension(extension):
    from distutils.core import setup
    old_args = sys.argv
    sys.argv = [old_args[0], "build_ext", "--inplace"]
    setup(ext_modules = [extension])
    sys.argv = old_args

def change_file_extension(path, newExtension):
    return os.path.splitext(path)[0] + newExtension

def get_file_name_without_extension(path):
    return os.path.basename(os.path.splitext(path)[0])

if __name__ == '__main__':
    main()