python_local_dynamodb_connection.py

import boto3

# For a Boto3 client.
ddb = boto3.client('dynamodb', endpoint_url='http://localhost:8000')
response = ddb.list_tables()
print(response)

# For a Boto3 service resource
ddb = boto3.resource('dynamodb', endpoint_url='http://localhost:8000')
print(list(ddb.tables.all()))