Example of Uniprot REST API (Python)

uniprot_rest_example.py

#!/usr/bin/env python

"""
Queries Uniprot database and retrieves (canonical) sequences.
"""

import argparse
import sys
import urllib.request

ap = argparse.ArgumentParser()
ap.add_argument('seqfile', help='Input file with protein names')
ap.add_argument('-o', dest='output', help='Output file for protein sequences')
args = ap.parse_args()

if args.output:
    ostream = open(args.output, 'w')
else:
    ostream = sys.stdout

with open(args.seqfile) as handle:
    for line in handle:
        line = line.strip()
        if not line:
            continue

        url = f'https://www.uniprot.org/uniprot/?query={line}&format=fasta'
        with urllib.request.urlopen(url) as r:
            fasta = r.read().decode('utf-8').strip()
        print(fasta, file=ostream)

if args.output:
    ostream.close()

Could you suggest how to use your snippet to get other information associated with Uniprot entry such as PDB ID, GO, PFAM ID etc?

Thanks very much.