fireworks mistral result for test.py

gistfile1.txt

## Text 1 - part of Text 3
NALP3, also known as cryopyrin, has been implicated in crystal-associated diseases such as gout and silicosis. Mice fed the diet high in soluble oxalate demonstrated increased NALP3 expression in the kidney.

{
    "NALP3": {
        "_ENTITY_TYPE": "Drug"
    },
    "cryopyrin": {
        "_ENTITY_TYPE": "Drug",
        "abbreviation of": "NALP3"
    },
    "gout": {
        "implicated in": [
            "NALP3"
        ],
        "_ENTITY_TYPE": "Disease"
    },
    "silicosis": {
        "implicated in": [
            "NALP3"
        ],
        "_ENTITY_TYPE": "Disease"
    },
    "mice": {
        "_ENTITY_TYPE": "Other"
    },
    "diet": {
        "composition": [
            "soluble oxalate"
        ],
        "_ENTITY_TYPE": "Other"
    },
    "soluble oxalate": {
        "composition of": [
            "diet"
        ],
        "_ENTITY_TYPE": "Other"
    },
    "kidney": {
        "expression of": [
            "NALP3"
        ],
        "_ENTITY_TYPE": "Other"
    }
}

## Text 2
The pandemic of obesity, type 2 diabetes mellitus (T2DM) and nonalcoholic fatty liver disease (NAFLD) has frequently been associated with dietary intake of saturated fats (1) and specifically with dietary palm oil

{
  "obesity": {
    "_ENTITY_TYPE": "Disease"
  },
  "type 2 diabetes mellitus": {
    "_ENTITY_TYPE": "Disease"
  },
  "T2DM": {
    "abbreviation of": "type 2 diabetes mellitus",
    "_ENTITY_TYPE": "Disease"
  },
  "nonalcoholic fatty liver disease": {
    "_ENTITY_TYPE": "Disease"
  },
  "NAFLD": {
    "abbreviation of": "nonalcoholic fatty liver disease",
    "_ENTITY_TYPE": "Disease"
  },
  "dietary intake": {
    "_ENTITY_TYPE": "Other"
  },
  "saturation fats": {
    "_ENTITY_TYPE": "Drug"
  },
  "saturated fats": {
    "synonym of": "saturation fats",
    "_ENTITY_TYPE": "Drug"
  },
  "palm oil": {
    "_ENTITY_TYPE": "Drug"
  }
}
## Text 3
Oxalate nephropathy with renal failure is caused by multiple disorders causing hyperoxaluria due to either overproduction of oxalate (primary hyperoxaluria) or excessive absorption of dietary oxalate (enteric hyperoxaluria). To study the etiology of renal failure in crystal-induced kidney disease, we created a model of progressive oxalate nephropathy by feeding mice a diet high in soluble oxalate (high oxalate in the absence of dietary calcium). Renal histology was characterized by intratubular calcium-oxalate crystal deposition with an inflammatory response in the surrounding interstitium. Oxalate nephropathy was not found in mice fed a high oxalate diet that also contained calcium. NALP3, also known as cryopyrin, has been implicated in crystal-associated diseases such as gout and silicosis. Mice fed the diet high in soluble oxalate demonstrated increased NALP3 expression in the kidney. Nalp3-null mice were completely protected from the progressive renal failure and death that occurred in wild-type mice fed the diet high in soluble oxalate. NALP3-deficiency did not affect oxalate homeostasis, thereby excluding differences in intestinal oxalate handling to explain the observed phenotype. Thus, progressive renal failure in oxalate nephropathy results primarily from NALP3-mediated inflammation.

{
    "Multiple disorders": {
        "_ENTITY_TYPE": "Other"
    },
    "Hyperoxaluria": {
        "_ENTITY_TYPE": "Disease"
    },
    "Primary hyperoxaluria": {
        "_ENTITY_TYPE": "Disease"
    },
    "Enteric hyperoxaluria": {
        "_ENTITY_TYPE": "Disease"
    },
    "Oxalate nephropathy with renal failure": {
        "caused by": [
            "Multiple disorders causing hyperoxaluria"
        ],
        "_ENTITY_TYPE": "Disease"
    },
    "Oxalate": {
        "overproduction of": [
            "Primary hyperoxaluria"
        ],
        "excessive absorption of": [
            "Enteric hyperoxaluria"
        ],
        "_ENTITY_TYPE": "Drug"
    },
    "Mice": {
        "created a model of": [
            "Progressive oxalate nephropathy"
        ],
        "_ENTITY_TYPE": "Other"
    },
    "Diet high in soluble oxalate": {
        "caused by": [
            "Hyperoxaluria"
        ],
        "_ENTITY_TYPE": "Other"
    },
    "High oxalate": {
        "in the absence of": [
            "Dietary calcium"
        ],
        "_ENTITY_TYPE": "Other"
    },
    "Intratubular calcium-oxalate crystal deposition": {
        "characterized renal histology": [
            "Oxalate nephropathy"
        ],
        "_ENTITY_TYPE": "Disease"
    },
    "NALP3": {
        "implicated in": [
            "Crystal-associated diseases"
        ],
        "expression increased in": [
            "Kidney"
        ],
        "_ENTITY_TYPE": "Drug"
    },
    "Gout": {
        "crystal-associated diseases": [
            "NALP3"
        ],
        "_ENTITY_TYPE": "Disease"
    },
    "Silicosis": {
        "crystal-associated diseases": [
            "NALP3"
        ],
        "_ENTITY_TYPE": "Disease"
    },
    "Nalp3-null mice": {
        "protected from": [
            "Progressive renal failure",
            "Death"
        ],
        "_ENTITY_TYPE": "Other"
    },
    "NALP3-deficiency": {
        "did not affect": [
            "Oxalate homeostasis"
        ],
        "_ENTITY_TYPE": "Other"
    },
    "Intestinal oxalate handling": {
        "excluded": [
            "NALP3-mediated inflammation"
        ],
        "_ENTITY_TYPE": "Other"
    },
    "Progressive renal failure": {
        "resulted primarily from": [
            "NALP3-mediated inflammation"
        ],
        "_ENTITY_TYPE": "Disease"
    }
}