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@MarkDunne
Created April 10, 2018 21:00
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NCG List
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entrez symbol description locus hprd hgnc mim refpro refdna ensembl uniprot cancer cancer_type cancer_dom cancer_rec duplicability origin mirna function chromosome tstart tend aliases main_refseq duplicability_main_refseq potential_false_positive primary_sites degree betweenness clustering complexes
25 ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase 9q34.1 1809 76 189980 NP_005148;NP_009297 NM_005157;NM_007313 ENSP00000361423 P00519 TRUE cgc 1 0 0 Eukaryotes 3 Cell cycle,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction chr9 133589707 133761067 |JTK7|bcr/abl|c-ABL|c-ABL1|v-abl| NP_009297 0 FALSE 1 337 583638 0.0440 9
27 ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase 1q25.2 1259 77 164690 NP_001129472;NP_001129473;NP_001161708;NP_001161709;NP_001161710;NP_001161711;NP_005149;NP_009298;XP_005245145 NM_001136000;NM_001136001;NM_001168236;NM_001168237;NM_001168238;NM_001168239;NM_005158;NM_007314;XM_005245088 ENSP00000427562 P42684 TRUE cgc 1 0 0 Eukaryotes 5 Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism,Signal transduction chr1 179076856 179198532 |ABLL| NP_009298 0 FALSE 1 43 14338 0.2290 4
60 ACTB actin, beta 7p22 32 132 102630 NP_001092;XP_006715827 NM_001101;XM_006715764 ENSP00000224784;ENSP00000295137;ENSP00000326022;ENSP00000331514;ENSP00000350052;ENSP00000392718;ENSP00000439189;ENSP00000452296;ENSP00000469921 P60709 TRUE can 0 0 39 Last Universal Common Ancestor 2 Cell response to stimuli chr7 5567382 5569288 |BRWS1|PS1TP5BP1| NP_001092 39 FALSE 1 337 472339 0.0700 47
90 ACVR1 activin A receptor, type I 2q23-q24 21 171 102576 NP_001096;NP_001104537;XP_005246996;XP_005246997;XP_006712888 NM_001105;NM_001111067;XM_005246939;XM_005246940;XM_006712825 ENSP00000263640 Q04771 TRUE can 0 0 0 Metazoans 8 Cell cycle,Cell motility and interactions,Cell response to stimuli,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Immune system response,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction chr2 158594046 158656005 |ACTRI|ACVR1A|ACVRLK2|ALK2|SKR1|TSRI| NP_001096 0 FALSE 1 72 36125 0.0610 2
91 ACVR1B activin A receptor, type IB 12q13 3193 172 601300 NP_004293;NP_064732;NP_064733;XP_006719748 NM_004302;NM_020327;NM_020328;XM_006719685 ENSP00000442656 P36896 TRUE can 0 0 0 Metazoans 6 Cell cycle,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction chr12 52345528 52387891 |ACTRIB|ALK4|SKR2| NP_064733 0 FALSE 2 31 27232 0.1680 6
92 ACVR2A activin A receptor, type IIA 2q22.3 25 173 102581 NP_001265508;NP_001265509;NP_001607;XP_005263900 NM_001278579;NM_001278580;NM_001616;XM_005263843 ENSP00000241416 P27037 TRUE can 0 0 0 Metazoans 5 Cellular metabolism,Cellular processes,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Signal transduction chr2 148602722 148684840 |ACTRII|ACVR2| NP_001265508 0 FALSE 3 22 4534 0.1470 14
102 ADAM10 ADAM metallopeptidase domain 10 15q22 - 188 602192 NP_001101;XP_005254174 NM_001110;XM_005254117 ENSP00000260408 O14672 TRUE can 0 0 0 Opisthokonts 2 Cell motility and interactions,Cellular metabolism,Cellular processes,Development,Regulation of intracellular processes and metabolism,Signal transduction chr15 58889749 59041733 |AD18|CD156c|HsT18717|kuz| NP_001101 0 FALSE 1 24 37150 0.0470
107 ADCY1 adenylate cyclase 1 (brain) 7p13-p12 53 232 103072 NP_001268697;NP_066939;XP_005249641;XP_005249642 NM_001281768;NM_021116;XM_005249584;XM_005249585 ENSP00000297323 Q08828 TRUE can 0 0 0 Last Universal Common Ancestor 0 Cellular metabolism,DNA/RNA metabolism and transcription,Signal transduction chr7 45614143 45753591 |AC1| NP_066939 0 FALSE 1 2 267 0.0000 5
114 ADCY8 adenylate cyclase 8 (brain) 8q24 51 239 103070 NP_001106;XP_005250826;XP_006716564 NM_001115;XM_005250769;XM_006716501 ENSP00000260600;ENSP00000286355 P40145 TRUE can 0 0 0 Last Universal Common Ancestor 0 Cellular metabolism,DNA/RNA metabolism and transcription,Signal transduction chr8 131792639 132052579 |AC8|HBAC1| NP_001106 0 FALSE 1 3 64 0.3330 5
125 ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide 4q23 - 250 103720 NP_000659;NP_001273579;XP_006714142 NM_000668;NM_001286650;XM_006714079 ENSP00000306606 P00325 TRUE can 0 0 2 Last Universal Common Ancestor 0 Cellular metabolism chr4 100231924 100240043 |ADH2|HEL-S-117| NP_000659 2 FALSE 1 6 148 0.0000
173 AFM afamin 4q13.3 73 316 104145 NP_001124;XP_006714185 NM_001133;XM_006714122 ENSP00000226355 P43652 TRUE can 0 0 0 Vertebrates 0 -1 chr4 74347493 74367636 |ALB2|ALBA| NP_001124 0 FALSE 1
182 JAG1 jagged 1 20p12.1-p11.23 3562 6188 601920 NP_000205 NM_000214 ENSP00000254958 P78504 TRUE can 0 0 0 Eukaryotes 7 Cell cycle,Cell motility and interactions,Cellular processes,Development,Regulation of intracellular processes and metabolism,Signal transduction chr20 10620149 10654178 |AGS|AHD|AWS|CD339|HJ1|JAGL1| NP_000205 0 FALSE 1 13 1075 0.0900 9
187 APLNR apelin receptor 11q12 2503 339 600052 NP_005152 NM_005161;NR_027991 ENSP00000257254 P35414 TRUE can 0 0 0 Vertebrates 0 Signal transduction chr11 57003339 57004478 |AGTRL1|APJ|APJR|HG11| NP_005152 0 FALSE 1 1 0 0.0000 3
207 AKT1 v-akt murine thymoma viral oncogene homolog 1 14q32.32 1261 391 164730 NP_001014431;NP_001014432;NP_005154;XP_005267458 NM_001014431;NM_001014432;NM_005163;XM_005267401 ENSP00000270202 P31749 TRUE cgc 1 0 2 Last Universal Common Ancestor 11 Cell cycle,Cell response to stimuli,Cellular metabolism,Cellular processes,Development,Immune system response,Multicellular activities,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction chr14 105236681 105258980 |AKT|CWS6|PKB-ALPHA|PRKBA|RAC|RAC-ALPHA| NP_001014431 2 FALSE 5 329 499050 0.0440 20
208 AKT2 v-akt murine thymoma viral oncogene homolog 2 19q13.1-q13.2 1262 392 164731 NP_001229956;NP_001229957;NP_001617;XP_006723144;XP_006723145;XP_006723146;XP_006723147;XP_006723148 NM_001243027;NM_001243028;NM_001626;XM_006723081;XM_006723082;XM_006723083;XM_006723084;XM_006723085 ENSP00000375892 P31751 TRUE cgc 1 0 1 Last Universal Common Ancestor 5 Cellular metabolism,Cellular processes chr19 40739782 40771174 |HIHGHH|PKBB|PKBBETA|PRKBB|RAC-BETA| NP_001617 1 FALSE 3 54 40392 0.0930 2
213 ALB albumin 4q13.3 62 399 103600 NP_000468 NM_000477 ENSP00000295897;ENSP00000324292 P02768 TRUE can 0 0 0 Metazoans 0 Cell cycle,Cell motility and interactions,Cell response to stimuli,Cellular processes,Development,Other,Regulation of intracellular processes and metabolism chr4 74270045 74286012 |ANALBA|FDAH|PRO0883|PRO0903|PRO1341| NP_000468 0 FALSE 1 155 443620 0.0140 4
217 ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) 12q24.2 3 404 100650 NP_000681;NP_001191818 NM_000690;NM_001204889 ENSP00000261733 P05091 TRUE cgc 1 0 1 Last Universal Common Ancestor 5 Signal transduction chr12 112204787 112241786 |ALDH-E2|ALDHI|ALDM| NP_000681 1 FALSE 1 17 17852 0.0810 1
238 ALK anaplastic lymphoma receptor tyrosine kinase 2p23 104 427 105590 NP_004295 NM_004304 ENSP00000373700 Q9UM73 TRUE cgc 1 0 0 Eukaryotes 1 Cellular metabolism,Cellular processes,Development,Signal transduction chr2 29416093 30143525 |CD246|NBLST3| NP_004295 0 FALSE 3 67 30723 0.0790 1
239 ALOX12 arachidonate 12-lipoxygenase 17p13.1 1066 429 152391 NP_000688;XP_005256645;XP_006721559;XP_006721560 NM_000697;XM_005256588;XM_006721496;XM_006721497 ENSP00000251535 P18054 TRUE can 0 0 0 Last Universal Common Ancestor 0 Cell cycle,Cell motility and interactions,Cellular metabolism,Cellular processes,Development,Regulation of intracellular processes and metabolism chr17 6899437 6913739 |12S-LOX|LOG12| NP_000688 0 FALSE 1 8 231 0.0360
273 AMPH amphiphysin 7p14-p13 2687 471 600418 NP_001626;NP_647477;XP_006715752;XP_006715753;XP_006715754 NM_001635;NM_139316;XM_006715689;XM_006715690;XM_006715691 ENSP00000348602 P49418 TRUE can 0 0 0 Eukaryotes 0 Cellular processes,Multicellular activities chr7 38424422 38670951 |AMPH1| NP_001626 0 FALSE 1 40 12015 0.0970 7
280 AMY2B amylase, alpha 2B (pancreatic) 1p21 95 478 104660 NP_066188 NM_020978 ENSP00000397582 P19961 TRUE can 0 0 5 Last Universal Common Ancestor 0 -1 chr1 104114225 104122119 |AMY3|HXA| NP_066188 5 FALSE 1 2 6 0.0000
284 ANGPT1 angiopoietin 1 8q23.1 3392 484 601667 NP_001137;NP_001186788 NM_001146;NM_001199859;NM_139290 ENSP00000428340 Q15389 TRUE can 0 0 0 Eukaryotes 0 Development,Signal transduction chr8 108264086 108509786 |AGPT| NP_001137 0 FALSE 1 4 64 0.1670 9
287 ANK2 ankyrin 2, neuronal 4q25-q27 110 493 106410 NP_001120965;NP_001139;NP_066187;XP_005262999;XP_005263002;XP_005263005;XP_006714250;XP_006714251;XP_006714252;XP_006714253;XP_006714254;XP_006714255;XP_006714256;XP_006714257 NM_001127493;NM_001148;NM_020977;XM_005262942;XM_005262945;XM_005262948;XM_006714187;XM_006714188;XM_006714189;XM_006714190;XM_006714191;XM_006714192;XM_006714193;XM_006714194 ENSP00000349588 Q01484 TRUE can 0 0 0 Last Universal Common Ancestor 2 Signal transduction chr4 114067025 114302793 |ANK-2|LQT4|brank-2| XP_005262999 0 FALSE 1 23 14007 0.0360 2
288 ANK3 ankyrin 3, node of Ranvier (ankyrin G) 10q21 2715 494 600465 NP_001140;NP_001191332;NP_001191333;NP_066267;XP_005269772;XP_005269773;XP_006717845;XP_006717846;XP_006717847;XP_006717848;XP_006717849;XP_006717850;XP_006717851;XP_006717852;XP_006717853;XP_006717854;XP_006717855;XP_006717856;XP_006717857;XP_006717858;XP_006717859;XP_006717860;XP_006717861;XP_006717862;XP_006717863;XP_006717864;XP_006717865;XP_006717866 NM_001149;NM_001204403;NM_001204404;NM_020987;XM_005269715;XM_005269716;XM_006717782;XM_006717783;XM_006717784;XM_006717785;XM_006717786;XM_006717787;XM_006717788;XM_006717789;XM_006717790;XM_006717791;XM_006717792;XM_006717793;XM_006717794;XM_006717795;XM_006717796;XM_006717797;XM_006717798;XM_006717799;XM_006717800;XM_006717801;XM_006717802;XM_006717803 ENSP00000280772 Q12955 TRUE can 0 0 0 Last Universal Common Ancestor 0 Cellular processes,Signal transduction chr10 61802452 62149296 |ANKYRIN-G|MRT37| NP_066267 0 FALSE 2 18 21918 0.0390
290 ANPEP alanyl (membrane) aminopeptidase 15q25-q26 1055 500 151530 NP_001141;XP_005254949 NM_001150;XM_005254892 ENSP00000300060 P15144 TRUE can 0 0 0 Last Universal Common Ancestor 11 Cellular metabolism,Development chr15 90328583 90349814 |APN|CD13|GP150|PEPN| NP_001141 0 FALSE 1 1 0 0.0000
324 APC adenomatous polyposis coli 5q21-q22 1439 583 611731 NP_000029;NP_001120982;NP_001120983 NM_000038;NM_001127510;NM_001127511 ENSP00000234071;ENSP00000257430 P25054 TRUE cgc 0 1 0 Last Universal Common Ancestor 8 Cell cycle,Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism,Signal transduction chr5 112090588 112179820 |BTPS2|DP2.5|PPP1R46| NP_000029 0 FALSE 7 171 210940 0.0260 26
330 BIRC3 baculoviral IAP repeat containing 3 11q22 3426 591 601721 NP_001156;NP_892007 NM_001165;NM_182962 ENSP00000263464 Q13489 TRUE cgc 1 0 0 Eukaryotes 3 Cell cycle,Development,Regulation of intracellular processes and metabolism,Signal transduction chr11 102195241 102207830 |API2|CIAP2|HAIP1|HIAP1|MALT2|RNF49|c-IAP2| NP_001156 0 FALSE 1 74 13562 0.1400 14
338 APOB apolipoprotein B 2p24-p23 133 603 107730 NP_000375 NM_000384 ENSP00000233242 P04114 TRUE can 0 0 0 Metazoans 0 Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism chr2 21224605 21265346 |FLDB|LDLCQ4| NP_000375 0 FALSE 2 33 18547 0.0890 30
355 FAS Fas cell surface death receptor 10q24.1 609 11920 134637 NP_000034;NP_690610;NP_690611;XP_006717882 NM_000043;NM_152871;NM_152872;NM_152873;NM_152874;NM_152875;NM_152876;NM_152877;NR_028033;NR_028034;NR_028035;NR_028036;XM_006717819 ENSP00000304592 P25445 TRUE cgc 0 1 0 Last Universal Common Ancestor 4 Cell cycle,Development,Regulation of intracellular processes and metabolism,Signal transduction chr10 90762786 90774204 |ALPS1A|APO-1|CD95|FAS1|FASTM|TNFRSF6| NP_000034 0 FALSE 2 71 28419 0.1040 16
367 AR androgen receptor Xq12 2437 644 313700 NP_000035;NP_001011645 NM_000044;NM_001011645 ENSP00000285930 P10275 TRUE can 0 0 0 Last Universal Common Ancestor 5 Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction chrX 66764989 66943680 |DHTR|HUMARA|HYSP1|KD|NR3C4|SBMA|SMAX1|TFM| NP_000035 0 FALSE 1 326 408371 0.0540 13
387 RHOA ras homolog family member A 3p21.3 1323 667 165390 NP_001655 NM_001664 ENSP00000400175 P61586 TRUE can 0 0 3 Eukaryotes 9 Cellular processes,Regulation of intracellular processes and metabolism,Signal transduction chr3 49397645 49413022 |ARH12|ARHA|RHO12|RHOH12| NP_001655 3 FALSE 3 131 104020 0.0350 35
388 RHOB ras homolog family member B 2p24 1321 668 165370 NP_004031 NM_004040 ENSP00000272233 P62745 TRUE can 0 0 2 Eukaryotes 5 Cell cycle,Cellular processes,Development,Regulation of intracellular processes and metabolism,Signal transduction chr2 20647227 20647814 |ARH6|ARHB|MST081|MSTP081|RHOH6| NP_004031 2 FALSE 1 33 16308 0.0360 11
399 RHOH ras homolog family member H 4p13 - 686 602037 NP_001265288;NP_001265289;NP_001265290;NP_001265291;NP_001265292;NP_001265293;NP_001265294;NP_001265295;NP_001265296;NP_001265297;NP_001265298;NP_004301;XP_006714076 NM_001278359;NM_001278360;NM_001278361;NM_001278362;NM_001278363;NM_001278364;NM_001278365;NM_001278366;NM_001278367;NM_001278368;NM_001278369;NM_004310;XM_006714013 ENSP00000371219 Q15669 TRUE cgc 1 0 0 Eukaryotes 0 Cellular metabolism,DNA/RNA metabolism and transcription,Development,Immune system response,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction chr4 40245007 40245579 |ARHH|TTF| NP_001265288 0 FALSE 1 10 468 0.0000 1
405 ARNT aryl hydrocarbon receptor nuclear translocator 1q21 524 700 126110 NP_001184254;NP_001272964;NP_001272965;NP_001659;NP_848514;XP_005245208;XP_005245210;XP_005245211;XP_005245214 NM_001197325;NM_001286035;NM_001286036;NM_001668;NM_178426;NM_178427;XM_005245151;XM_005245153;XM_005245154;XM_005245157 ENSP00000340900 P27540 TRUE cgc 1 0 0 Eukaryotes 1 Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction chr1 150784500 150830937 |HIF-1-beta|HIF-1beta|HIF1-beta|HIF1B|HIF1BETA|bHLHe2| NP_001659 0 FALSE 1 44 22083 0.1260 10
435 ASL argininosuccinate lyase 7q11.21 1948 746 608310 NP_000039;NP_001020114;NP_001020115;NP_001020117 NM_000048;NM_001024943;NM_001024944;NM_001024946 ENSP00000216194 P04424 TRUE can 0 0 0 Last Universal Common Ancestor 0 Cell response to stimuli,Cellular metabolism,Cellular processes,Development chr7 65546790 65557896 |ASAL| NP_000039 0 FALSE 1 14 1733 0.0550
460 ASTN1 astrotactin 1 1q25.2 9019 773 600904 NP_001273093;NP_004310;NP_996991 NM_001286164;NM_004319;NM_207108 ENSP00000354536 O14525 TRUE can 0 0 0 Metazoans 1 Cell motility and interactions chr1 176833423 177133812 |ASTN| NP_004310 0 FALSE 1
463 ZFHX3 zinc finger homeobox 3 16q22.3 75 777 104155 NP_001158238;NP_008816;XP_005256014 NM_001164766;NM_006885;XM_005255957 ENSP00000268489 Q15911 TRUE can 0 0 0 Metazoans 6 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr16 72821066 72994044 |ATBF1|ATBT|ZNF927| NP_008816 0 FALSE 3 9 1444 0.1390
466 ATF1 activating transcription factor 1 12q13 440 783 123803 NP_005162 NM_005171 ENSP00000264110;ENSP00000409007 P18846 TRUE cgc 1 0 0 Vertebrates 2 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr12 51173929 51213559 |EWS-ATF1|FUS/ATF-1|TREB36| NP_005162 0 FALSE 1 22 1755 0.2120
471 ATIC 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase 2q35 3434 794 601731 NP_004035;XP_006712608 NM_004044;XM_006712545 ENSP00000236959 P31939 TRUE cgc 1 0 0 Last Universal Common Ancestor 0 Cellular metabolism,DNA/RNA metabolism and transcription,Development chr2 216177220 216214375 |AICAR|AICARFT|HEL-S-70p|IMPCHASE|PURH| NP_004035 0 FALSE 1 48 12642 0.1190
472 ATM ATM serine/threonine kinase 11q22-q23 6347 795 607585 NP_000042;XP_005271618;XP_005271619;XP_005271621;XP_006718906;XP_006718907;XP_006718908 NM_000051;NM_138292;NM_138293;XM_005271561;XM_005271562;XM_005271564;XM_006718843;XM_006718844;XM_006718845 ENSP00000278616 Q13315 TRUE cgc 0 1 0 Eukaryotes 10 Cell cycle,Cell response to stimuli,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Signal transduction chr11 108098352 108236232 |ATA|ATC|ATE|TEL1|TELO1| NP_000042 0 FALSE 8 143 120036 0.0770 15
476 ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide 1p21 1662 799 182310 NP_000692;NP_001153705;NP_001153706;XP_006710718 NM_000701;NM_001001586;NM_001160233;NM_001160234;XM_006710655 ENSP00000295598;ENSP00000357060 P05023 TRUE cgc 1 0 3 Last Universal Common Ancestor 3 Cell motility and interactions,Cellular processes,Regulation of intracellular processes and metabolism chr1 116926636 116946599 |NA| NP_000692 3 FALSE 1 58 20245 0.0620
488 ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 12q24.11 161 812 108740 NP_001672;NP_733765;XP_005253945 NM_001135765;NM_001681;NM_170665;XM_005253888;XR_243009 ENSP00000440045 P16615 TRUE can 0 0 2 Last Universal Common Ancestor 4 Cellular processes,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Signal transduction chr12 110719595 110784272 |ATP2B|SERCA2| NP_733765 2 FALSE 1 50 26871 0.0660
492 ATP2B3 ATPase, Ca++ transporting, plasma membrane 3 Xq28 2057 816 300014 NP_001001344;NP_068768;XP_005274746;XP_005274747;XP_005274748;XP_005274749;XP_005274750;XP_006724886 NM_001001344;NM_021949;XM_005274689;XM_005274690;XM_005274691;XM_005274692;XM_005274693;XM_006724823 ENSP00000263519;ENSP00000461370 Q16720 TRUE cgc 1 0 3 Last Universal Common Ancestor 0 Cellular processes chrX 152801706 152845753 |CFAP39|CLA2|OPCA|PMCA3|PMCA3a|SCAX1| XP_005274746 3 FALSE 1 3 41 0.0000
495 ATP4A ATPase, H+/K+ exchanging, alpha polypeptide 19q13.1 668 819 137216 NP_000695 NM_000704 ENSP00000262623 P20648 TRUE can 0 0 0 Last Universal Common Ancestor 0 Cellular processes chr19 36041734 36054429 |ATP6A| NP_000695 0 FALSE 1 74 98173 0.0120
545 ATR ATR serine/threonine kinase 3q23 8369 882 601215 NP_001175 NM_001184;XR_241498 ENSP00000445920 Q13535 TRUE can 0 0 0 Eukaryotes 0 Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction chr3 142168274 142297546 |FCTCS|MEC1|SCKL|SCKL1| NP_001175 0 FALSE 2 86 21093 0.1110 5
546 ATRX alpha thalassemia/mental retardation syndrome X-linked Xq21.1 2069 886 300032 NP_000480;NP_612114;XP_005262210;XP_005262211;XP_005262212;XP_005262213;XP_005262214;XP_006724729;XP_006724730;XP_006724731 NM_000489;NM_138270;NM_138271;XM_005262153;XM_005262154;XM_005262155;XM_005262156;XM_005262157;XM_006724666;XM_006724667;XM_006724668 ENSP00000362441;ENSP00000472963 P46100 TRUE cgc 0 1 0 Last Universal Common Ancestor 2 Cell response to stimuli,Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chrX 76763832 76972722 |ATR2|JMS|MRXHF1|RAD54|SFM1|XH2|XNP|ZNF-HX| NP_000480 0 FALSE 5 41 4909 0.1270 2
567 B2M beta-2-microglobulin 15q21-q22.2 - 914 109700 NP_004039;XP_005254606;XP_006725245 NM_004048;XM_005254549;XM_006725182 ENSP00000460997 P61769 TRUE can 0 0 0 Vertebrates 1 Immune system response chr15 45003745 45007919 |NA| XP_005254606 0 FALSE 2 28 39964 0.0850 28
577 BAI3 brain-specific angiogenesis inhibitor 3 6q12 4064 945 602684 NP_001695;XP_005248809;XP_005248810;XP_006715597 NM_001704;XM_005248752;XM_005248753;XM_006715534 ENSP00000359630 O60242 TRUE can 0 0 0 Metazoans 1 Signal transduction chr6 69348568 70098780 |NA| NP_001695 0 FALSE 4 3 210 0.0000
595 CCND1 cyclin D1 11q13 1346 1582 168461 NP_444284;XP_006718716 NM_053056;XM_006718653 ENSP00000227507 P24385 TRUE cgc 1 0 0 Eukaryotes 31 Cell cycle,Cell response to stimuli,Cellular metabolism,Cellular processes,Development,Regulation of intracellular processes and metabolism,Signal transduction chr11 69456082 69466047 |BCL1|D11S287E|PRAD1|U21B31| NP_444284 0 FALSE 7 101 52556 0.1040 23
596 BCL2 B-cell CLL/lymphoma 2 18q21.3 - 990 151430 NP_000624;NP_000648;XP_006722586 NM_000633;NM_000657;XM_006722523;XR_430082 ENSP00000329623 P10415 TRUE cgc 1 0 0 Metazoans 44 Cell cycle,Cell response to stimuli,Cellular processes,Development,Immune system response,Multicellular activities,Other,Regulation of intracellular processes and metabolism,Signal transduction chr18 60795861 60985899 |Bcl-2|PPP1R50| NP_000624 0 FALSE 1 112 80689 0.0670 8
602 BCL3 B-cell CLL/lymphoma 3 19q13.1-q13.2 179 998 109560 NP_005169;XP_005259186 NM_005178;XM_005259129 ENSP00000164227 P20749 TRUE cgc 1 0 0 Last Universal Common Ancestor 1 Cell cycle,Cell motility and interactions,Cell response to stimuli,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Immune system response,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction chr19 45246074 45262869 |BCL4|D19S37| XP_005259186 0 FALSE 1 49 7811 0.1930 2
603 BCL5 B-cell CLL/lymphoma 5 17q22 - - 151441 - - ENSP00000232014 NA TRUE cgc 1 0 -1 Eukaryotes 0 -1 - 0 0 |NA| - -1 FALSE 1
604 BCL6 B-cell CLL/lymphoma 6 3q27 180 1001 109565 NP_001124317;NP_001128210;NP_001697;XP_005247751 NM_001130845;NM_001134738;NM_001706;NM_138931;XM_005247694 ENSP00000232014 P41182 TRUE cgc 1 0 0 Eukaryotes 8 Cell cycle,Cell motility and interactions,Cell response to stimuli,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Immune system response,Multicellular activities,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction chr3 187440249 187451481 |BCL6A|LAZ3|ZBTB27|ZNF51| NP_001124317 0 FALSE 1 113 146591 0.0540 6
605 BCL7A B-cell CLL/lymphoma 7A 12q24.13 - 1004 601406 NP_001019979;NP_066273 NM_001024808;NM_020993 ENSP00000445868 Q4VC05 TRUE cgc 1 0 0 Metazoans 2 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr12 122459998 122497066 |BCL7| NP_066273 0 FALSE 1 7 200 0.3810
607 BCL9 B-cell CLL/lymphoma 9 1q21 4000 1008 602597 NP_004317;XP_005273028;XP_005277474;XP_005277475;XP_006711546 NM_004326;XM_005272971;XM_005277417;XM_005277418;XM_006711483 ENSP00000234739;ENSP00000464022 O00512 TRUE cgc 1 0 0 Vertebrates 3 Signal transduction chr1 147083636 147096757 |NA| NP_004317 0 FALSE 1 7 878 0.3330 3
608 TNFRSF17 tumor necrosis factor receptor superfamily, member 17 16p13.1 144 11913 109545 NP_001183 NM_001192 ENSP00000053243 Q02223 TRUE cgc 1 0 0 Vertebrates 1 Signal transduction chr16 12059182 12061701 |BCM|BCMA|CD269|TNFRSF13A| NP_001183 0 FALSE 1 6 148 0.5330 1
613 BCR breakpoint cluster region 22q11.23 1044 1014 151410 NP_004318;NP_067585 NM_004327;NM_021574 ENSP00000303507 P11274 TRUE cgc 1 0 0 Eukaryotes 0 Cellular metabolism,Cellular processes,Signal transduction chr22 23523148 23657706 |ALL|BCR1|CML|D22S11|D22S662|PHL| NP_004318 0 FALSE 1 76 37159 0.1480 10
639 PRDM1 PR domain containing 1, with ZNF domain 6q21 4572 9346 603423 NP_001189;NP_878911;XP_005267151;XP_006715613 NM_001198;NM_182907;XM_005267094;XM_006715550 ENSP00000358092 O75626 TRUE cgc 0 1 0 Metazoans 12 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr6 106534429 106555358 |BLIMP1|PRDI-BF1| NP_001189 0 FALSE 1 23 5872 0.1110
641 BLM Bloom syndrome, RecQ helicase-like 15q26.1 5211 1058 604610 NP_000048;NP_001274175;NP_001274176;NP_001274177;XP_006720695 NM_000057;NM_001287246;NM_001287247;NM_001287248;XM_006720632 ENSP00000347232 P54132 TRUE cgc 0 1 0 Last Universal Common Ancestor 3 Cell cycle,Cell response to stimuli,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Immune system response,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction chr15 91290623 91358506 |RECQ2| NP_000048 0 FALSE 1 69 22417 0.1510 22
657 BMPR1A bone morphogenetic protein receptor, type IA 10q22.3 - 1076 601299 NP_004320 NM_004329 ENSP00000224764 P36894 TRUE cgc 0 1 2 Last Universal Common Ancestor 3 Cell cycle,Cellular metabolism,Cellular processes,Development,Other,Regulation of intracellular processes and metabolism,Signal transduction chr10 88635776 88683473 |ACVRLK3|ALK3|CD292|SKR5| NP_004320 2 FALSE 1 54 39908 0.0640 7
667 DST dystonin 6p12.1 222 1090 113810 NP_001138241;NP_001138242;NP_001714;NP_056363;NP_899236;XP_005249367;XP_005249368;XP_005249369;XP_005249370;XP_005249371;XP_005249372;XP_005249373;XP_005249374;XP_005249375;XP_005249376;XP_005249377;XP_005249379;XP_005249380;XP_005249381;XP_005249382;XP_005249383;XP_006715232 NM_001144769;NM_001144770;NM_001144771;NM_001723;NM_015548;NM_020388;NM_183380;XM_005249310;XM_005249311;XM_005249312;XM_005249313;XM_005249314;XM_005249315;XM_005249316;XM_005249317;XM_005249318;XM_005249319;XM_005249320;XM_005249322;XM_005249323;XM_005249324;XM_005249325;XM_005249326;XM_006715169 ENSP00000354573 Q03001 TRUE can 0 0 0 Eukaryotes 4 Cell cycle,Cellular processes,Signal transduction chr6 56323806 56819385 |BP240|BPA|BPAG1|CATX-15|CATX15|D6S1101|DMH|DT|EBSB2|HSAN6|MACF2| XP_005249367 0 FALSE 1 52 16980 0.0410 1
668 FOXL2 forkhead box L2 3q23 5723 1092 605597 NP_075555 NM_023067 ENSP00000333188 P58012 TRUE cgc 1 0 0 Eukaryotes 0 Cell cycle,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction chr3 138664437 138665564 |BPES|BPES1|PFRK|PINTO|POF3| NP_075555 0 FALSE 1 5 194 0.0000
672 BRCA1 breast cancer 1, early onset 17q21 218 1100 113705 NP_009225;NP_009228;NP_009229;NP_009230;NP_009231;XP_006722092;XP_006722093;XP_006722094;XP_006722095;XP_006722096;XP_006722097;XP_006722098;XP_006722099;XP_006722100;XP_006722101;XP_006722102;XP_006722103;XP_006722104 NM_007294;NM_007295;NM_007296;NM_007297;NM_007298;NM_007299;NM_007300;NM_007301;NM_007302;NM_007303;NM_007305;NM_007306;NR_027676;XM_006722029;XM_006722030;XM_006722031;XM_006722032;XM_006722033;XM_006722034;XM_006722035;XM_006722036;XM_006722037;XM_006722038;XM_006722039;XM_006722040;XM_006722041 ENSP00000418960 P38398 TRUE cgc 0 1 0 Eukaryotes 11 Cell cycle,Cell response to stimuli,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction chr17 41197698 41276113 |BRCAI|BROVCA1|IRIS|PNCA4|PPP1R53|PSCP|RNF53| NP_009231 0 FALSE 4 523 1042415 0.0320 52
673 BRAF B-Raf proto-oncogene, serine/threonine kinase 7q34 1264 1097 164757 NP_004324;XP_005250102;XP_005250103 NM_004333;XM_005250045;XM_005250046;XR_242190 ENSP00000288602 P15056 TRUE cgc 1 0 1 Eukaryotes 0 Cell cycle,Cellular metabolism,Cellular processes,Development,Regulation of intracellular processes and metabolism,Signal transduction chr7 140434409 140624503 |B-RAF1|BRAF1|NS7|RAFB1| XP_005250102 1 FALSE 9 55 10211 0.1620 25
675 BRCA2 breast cancer 2, early onset 13q12.3 2554 1101 600185 NP_000050 NM_000059 ENSP00000326819;ENSP00000369497 P51587 TRUE cgc 0 1 0 Eukaryotes 6 Cell cycle,Cell response to stimuli,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction chr13 32890598 32972904 |BROVCA2|FANCD1|GLM3|PNCA2| NP_000050 0 FALSE 5 58 21834 0.1130 10
677 ZFP36L1 ZFP36 ring finger protein-like 1 14q22-q24 3041 1107 601064 NP_001231627;NP_001231630;NP_004917 NM_001244698;NM_001244701;NM_004926 ENSP00000337386;ENSP00000448323 Q07352 TRUE can 0 0 0 Eukaryotes 4 Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription chr14 69256253 69262866 |Berg36|ERF-1|RNF162B|TIS11B|cMG1| NP_001231630 0 FALSE 2 12 2036 0.1970 3
688 KLF5 Kruppel-like factor 5 (intestinal) 13q22.1 4212 6349 602903 NP_001273747;NP_001721;XP_005266566;XP_006719925 NM_001286818;NM_001730;XM_005266509;XM_006719862 ENSP00000264001;ENSP00000366915 Q13887 TRUE can 0 0 0 Eukaryotes 7 Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription chr13 73633466 73650021 |BTEB2|IKLF| NP_001721 0 FALSE 1 30 3015 0.2300
694 BTG1 B-cell translocation gene 1, anti-proliferative 12q22 15912 1130 109580 NP_001722 NM_001731 ENSP00000256015 P62324 TRUE cgc 1 0 0 Eukaryotes 1 Cell cycle,Cell motility and interactions,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Regulation of transcription chr12 92537859 92539311 |NA| NP_001722 0 FALSE 1 21 1398 0.1330
701 BUB1B BUB1 mitotic checkpoint serine/threonine kinase B 15q15 4176 1149 602860 NP_001202 NM_001211 ENSP00000287598 O60566 TRUE cgc 0 1 0 Eukaryotes 3 Cell cycle,Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism,Signal transduction chr15 40457252 40512957 |BUB1beta|BUBR1|Bub1A|MAD3L|MVA1|SSK1|hBUBR1| NP_001202 0 FALSE 1 73 22716 0.0960 18
718 C3 complement component 3 19p13.3-p13.2 400 1318 120700 NP_000055 NM_000064 ENSP00000245907 P01024 TRUE can 0 0 0 Metazoans 2 Cell response to stimuli,Cellular metabolism,Cellular processes,Immune system response,Regulation of intracellular processes and metabolism,Signal transduction chr19 6677896 6720600 |AHUS5|ARMD9|C3a|C3b|CPAMD1|HEL-S-62p| NP_000055 0 FALSE 1 31 56783 0.0300 21
776 CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit 3p14.3 247 1391 114206 NP_000711;NP_001122311;NP_001122312;XP_005265505;XP_006713388 NM_000720;NM_001128839;NM_001128840;XM_005265448;XM_006713325 ENSP00000288139 Q01668 TRUE cgc 1 0 0 Eukaryotes 0 Cell response to stimuli,Cellular processes,Signal transduction chr3 53529194 53845430 |CACH3|CACN4|CACNL1A2|CCHL1A2|Cav1.3|PASNA|SANDD| NP_000711 0 FALSE 1 4 191 0.0000
777 CACNA1E calcium channel, voltage-dependent, R type, alpha 1E subunit 1q25.3 3006 1392 601013 NP_000712;NP_001192222;NP_001192223 NM_000721;NM_001205293;NM_001205294 ENSP00000356545 Q15878 TRUE can 0 0 0 Eukaryotes 0 Cellular processes,Multicellular activities chr1 181452881 181767967 |BII|CACH6|CACNL1A6|Cav2.3| NP_001192222 0 FALSE 1 3 134 0.0000
781 CACNA2D1 calcium channel, voltage-dependent, alpha 2/delta subunit 1 7q21-q22 245 1399 114204 NP_000713;XP_005250627;XP_005250629;XP_005250630;XP_005250631;XP_006716181;XP_006716182;XP_006716183;XP_006716184 NM_000722;XM_005250570;XM_005250572;XM_005250573;XM_005250574;XM_006716118;XM_006716119;XM_006716120;XM_006716121 ENSP00000349320 P54289 TRUE can 0 0 0 Eukaryotes 4 Cellular processes chr7 81579711 82072775 |CACNA2|CACNL2A|CCHL2A| XP_005250627 0 FALSE 2 4 72 0.0000
799 CALCR calcitonin receptor 7q21.3 239 1440 114131 NP_001158209;NP_001158210;NP_001733 NM_001164737;NM_001164738;NM_001742 ENSP00000352561 P30988 TRUE can 0 0 0 Metazoans 0 Cell response to stimuli,Regulation of intracellular processes and metabolism,Signal transduction chr7 93055671 93116320 |CT-R|CTR| NP_001158209 0 FALSE 1 16 9807 0.0500 4
811 CALR calreticulin 19p13.3-p13.2 169 1455 109091 NP_004334 NM_004343 ENSP00000320866 P27797 TRUE cgc 1 0 0 Eukaryotes 8 Cell cycle,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr19 13049494 13054724 |HEL-S-99n|RO|cC1qR| NP_004334 0 FALSE 1 91 99091 0.0730 14
833 CARS cysteinyl-tRNA synthetase 11p15.5 464 1493 123859 NP_001014437;NP_001181926;NP_001742;NP_644802;XP_006718403;XP_006718404;XP_006725192;XP_006725193 NM_001014437;NM_001014438;NM_001194997;NM_001751;NM_139273;NR_036542;XM_006718340;XM_006718341;XM_006725129;XM_006725130;XR_428857;XR_430701 ENSP00000369897 P49589 TRUE cgc 1 0 0 Last Universal Common Ancestor 1 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of transcription chr11 3022347 3069232 |CARS1|CYSRS|MGC:11246| NP_001014437 0 FALSE 1 30 5473 0.1890
841 CASP8 caspase 8, apoptosis-related cysteine peptidase 2q33-q34 3459 1509 601763 NP_001073593;NP_001073594;NP_001219;NP_203519;NP_203520;NP_203522;XP_005246942;XP_005246943;XP_005246944;XP_005246945;XP_005246946;XP_005246947;XP_005246948;XP_005246949;XP_005246950;XP_005246951;XP_005246952;XP_005246953;XP_006712852;XP_006712853;XP_006712854;XP_006712855;XP_006712856 NM_001080124;NM_001080125;NM_001228;NM_033355;NM_033356;NM_033357;NM_033358;XM_005246885;XM_005246886;XM_005246887;XM_005246888;XM_005246889;XM_005246890;XM_005246891;XM_005246892;XM_005246893;XM_005246894;XM_005246895;XM_005246896;XM_006712789;XM_006712790;XM_006712791;XM_006712792;XM_006712793;XR_241323 ENSP00000351273 Q14790 TRUE cgc 0 1 0 Metazoans 2 Cell cycle,Cellular metabolism,Development,Regulation of intracellular processes and metabolism,Signal transduction chr2 202122955 202151314 |ALPS2B|CAP4|Casp-8|FLICE|MACH|MCH5| NP_001073594 0 FALSE 4 167 161353 0.0590 39
861 RUNX1 runt-related transcription factor 1 21q22.3 1043 10471 151385 NP_001001890;NP_001116079;NP_001745;XP_005261125;XP_005261126 NM_001001890;NM_001122607;NM_001754;XM_005261068;XM_005261069 ENSP00000300305 Q01196 TRUE cgc 1 0 0 Metazoans 3 Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription chr21 36164435 36421196 |AML1|AMLCR1|CBFA2|EVI-1|PEBP2aB| NP_001745 0 FALSE 2 77 27315 0.1470 2
862 RUNX1T1 runt-related transcription factor 1; translocated to, 1 (cyclin D-related) 8q22 590 1535 133435 NP_001185554;NP_001185555;NP_001185556;NP_001185557;NP_001185558;NP_001185559;NP_001185560;NP_001185561;NP_001185562;NP_001185563;NP_001185608;NP_004340;NP_783552;NP_783553;NP_783554;XP_006716739 NM_001198625;NM_001198626;NM_001198627;NM_001198628;NM_001198629;NM_001198630;NM_001198631;NM_001198632;NM_001198633;NM_001198634;NM_001198679;NM_004349;NM_175634;NM_175635;NM_175636;XM_006716676 ENSP00000402257 Q06455 TRUE cgc 1 0 0 Metazoans 5 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr8 92972473 93107695 |AML1T1|CBFA2T1|ETO|MTG8|ZMYND2| NP_001185608 0 FALSE 2 63 25091 0.0790
863 CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3 16q24 4847 1537 603870 NP_005178;NP_787127;XP_005256380;XP_006721382;XP_006721383 NM_005187;NM_175931;XM_005256323;XM_006721319;XM_006721320 ENSP00000268679 O75081 TRUE cgc 1 0 0 Metazoans 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr16 88943387 89043215 |ETO2|MTG16|MTGR2|ZMYND4| NP_005178 0 FALSE 1 25 17598 0.1470 1
865 CBFB core-binding factor, beta subunit 16q22.1 418 1539 121360 NP_001746;NP_074036;XP_005256269;XP_006721384 NM_001755;NM_022845;XM_005256212;XM_006721321 ENSP00000415151 Q13951 TRUE cgc 1 0 0 Metazoans 7 Cellular metabolism,DNA/RNA metabolism and transcription chr16 67063311 67132678 |PEBP2B| NP_074036 0 FALSE 3 32 15294 0.0580 1
867 CBL Cbl proto-oncogene, E3 ubiquitin protein ligase 11q23.3 1320 1541 165360 NP_005179 NM_005188 ENSP00000264033 P22681 TRUE cgc 1 1 0 Metazoans 0 Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism,Signal transduction chr11 119077128 119170488 |C-CBL|CBL2|FRA11B|NSLL|RNF55| NP_005179 0 FALSE 3 234 207734 0.0730 78
868 CBLB Cbl proto-oncogene B, E3 ubiquitin protein ligase 3q13.11 5136 1542 604491 NP_733762;XP_005247909;XP_005247910;XP_006713859;XP_006713860 NM_170662;XM_005247852;XM_005247853;XM_006713796;XM_006713797;XR_427384;XR_427385 ENSP00000264122 Q13191 TRUE cgc 0 1 0 Metazoans 0 Cellular processes,Signal transduction chr3 105377817 105587082 |Cbl-b|RNF56| XP_005247909 0 FALSE 1 63 9131 0.2010 7
887 CCKBR cholecystokinin B receptor 11p15.4 323 1571 118445 NP_795344;XP_005253267 NM_176875;XM_005253210 ENSP00000335544 P32239 TRUE can 0 0 0 Metazoans 2 Cell cycle,Cell response to stimuli,Regulation of intracellular processes and metabolism,Signal transduction chr11 6281159 6292770 |CCK-B|CCK2R|GASR| XP_005253267 0 FALSE 1 12 11876 0.1670 4
894 CCND2 cyclin D2 12p13 451 1583 123833 NP_001750;XP_005253870 NM_001759;XM_005253813 ENSP00000261254 P30279 TRUE cgc 1 0 1 Eukaryotes 21 Cell cycle,Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism,Signal transduction chr12 4383207 4409172 |KIAK0002|MPPH3| NP_001750 1 FALSE 2 21 1000 0.1670 6
896 CCND3 cyclin D3 6p21 452 1585 123834 NP_001129489;NP_001129597;NP_001129598;NP_001274356;NP_001274363;NP_001751 NM_001136017;NM_001136125;NM_001136126;NM_001287427;NM_001287434;NM_001760 ENSP00000362082 P30281 TRUE cgc 1 0 0 Eukaryotes 4 Cell cycle,Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism,Signal transduction chr6 41903681 41909387 |NA| NP_001751 0 FALSE 4 44 17962 0.0780 6
898 CCNE1 cyclin E1 19q12 455 1589 123837 NP_001229;XP_005259427;XP_006723520 NM_001238;NM_057182;XM_005259370;XM_006723457 ENSP00000262643 P24864 TRUE cgc 1 0 0 Eukaryotes 13 Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction chr19 30303594 30314681 |CCNE| NP_001229 0 FALSE 1 69 11224 0.1240 18
910 CD1B CD1b molecule 1q23.1 1775 1635 188360 NP_001755 NM_001764 ENSP00000289429;ENSP00000357149;ENSP00000357150;ENSP00000357152;ENSP00000357153 P29016 TRUE can 0 0 0 Mammals 0 -1 chr1 158298710 158301213 |NA| NP_001755 0 FALSE 1 2 22 0.0000 1
940 CD28 CD28 molecule 2q33 1727 1653 186760 NP_001230006;NP_001230007;NP_006130;XP_006712925 NM_001243077;NM_001243078;NM_006139;XM_006712862 ENSP00000303939 P10747 TRUE can 0 0 0 Vertebrates 1 Cell cycle,Cell response to stimuli,Cellular metabolism,Development,Immune system response,Other,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction chr2 204571420 204599632 |Tp44| NP_006130 0 FALSE 1 20 20510 0.1790 12
944 TNFSF8 tumor necrosis factor (ligand) superfamily, member 8 9q33 - 11938 603875 NP_001235;NP_001239219;XP_006717388 NM_001244;NM_001252290;XM_006717325 ENSP00000223795 P32971 TRUE can 0 0 0 Vertebrates 0 Cell cycle,Development,Regulation of intracellular processes and metabolism,Signal transduction chr9 117666214 117692583 |CD153|CD30L|CD30LG| NP_001235 0 FALSE 1 2 7 0.0000
948 CD36 CD36 molecule (thrombospondin receptor) 7q11.2 1430 1663 173510 NP_000063;NP_001001547;NP_001001548;NP_001120915;NP_001120916;XP_005250770;XP_005250771;XP_005250772 NM_000072;NM_001001547;NM_001001548;NM_001127443;NM_001127444;XM_005250713;XM_005250714;XM_005250715 ENSP00000308165 P16671 TRUE can 0 0 0 Eukaryotes 3 Cellular processes,Multicellular activities chr7 80276057 80303460 |BDPLT10|CHDS7|GP3B|GP4|PASIV|SCARB3| NP_000063 0 FALSE 1 19 15551 0.1170 19
965 CD58 CD58 molecule 1p13 1081 1688 153420 NP_001138294;NP_001770 NM_001144822;NM_001779;NR_026665 ENSP00000358501 P19256 TRUE can 0 0 0 Vertebrates 0 -1 chr1 117064526 117113594 |LFA-3|LFA3|ag3| NP_001770 0 FALSE 1 4 376 0.1670 1
970 CD70 CD70 molecule 19p13 18515 11937 602840 NP_001243 NM_001252 ENSP00000245903 P32970 TRUE can 0 0 0 Mammals 0 Cell cycle,Development,Regulation of intracellular processes and metabolism,Signal transduction chr19 6586034 6591013 |CD27L|CD27LG|TNFSF7| NP_001243 0 FALSE 1 2 0 1.0000 1
972 CD74 CD74 molecule, major histocompatibility complex, class II invariant chain 5q32 825 1697 142790 NP_001020329;NP_001020330;NP_004346;XP_006714874 NM_001025158;NM_001025159;NM_004355;XM_006714811 ENSP00000009530 P04233 TRUE cgc 1 0 0 Eukaryotes 0 Cell cycle,Cellular metabolism,Cellular processes,Development,Immune system response,Regulation of intracellular processes and metabolism,Signal transduction chr5 149782127 149792312 |DHLAG|HLADG|Ia-GAMMA| NP_001020330 0 FALSE 1 16 23189 0.0420 14
973 CD79A CD79a molecule, immunoglobulin-associated alpha 19q13.2 203 1698 112205 NP_001774;NP_067612 NM_001783;NM_021601 ENSP00000221972 P11912 TRUE cgc 1 0 0 Vertebrates 1 Cell response to stimuli,Development,Immune system response,Signal transduction chr19 42381375 42385044 |IGA|MB-1| NP_001774 0 FALSE 1 19 19669 0.1990 5
974 CD79B CD79b molecule, immunoglobulin-associated beta 17q23 922 1699 147245 NP_000617;NP_001035022;NP_067613;XP_005257915 NM_000626;NM_001039933;NM_021602;XM_005257858 ENSP00000376544 P40259 TRUE cgc 1 0 0 Vertebrates 0 Signal transduction chr17 62006589 62009621 |AGM6|IGB| NP_001035022 0 FALSE 1 16 3539 0.3330 5
995 CDC25C cell division cycle 25C 5q31 1146 1727 157680 NP_001274511;NP_001274512;NP_001781;NP_073720;XP_005272202;XP_005272203;XP_006714802;XP_006714803 NM_001287582;NM_001287583;NM_001790;NM_022809;XM_005272145;XM_005272146;XM_006714739;XM_006714740 ENSP00000321656 P30307 TRUE can 0 0 0 Eukaryotes 1 Cell cycle,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Signal transduction chr5 137621384 137673844 |PPP1R60| NP_001274512 0 FALSE 1 38 23012 0.1790 2
996 CDC27 cell division cycle 27 17q21.32 304 1728 116946 NP_001107563;NP_001247;XP_005257949;XP_005257952;XP_006722280;XP_006722281;XP_006722282;XP_006722283;XP_006722284 NM_001114091;NM_001256;XM_005257892;XM_005257895;XM_006722217;XM_006722218;XM_006722219;XM_006722220;XM_006722221;XR_429935 ENSP00000434614 P30260 TRUE can 0 0 2 Last Universal Common Ancestor 6 Cell cycle,Cellular metabolism,Regulation of intracellular processes and metabolism chr17 45198304 45259006 |ANAPC3|APC3|CDC27Hs|D0S1430E|D17S978E|H-NUC|HNUC|NUC2| NP_001107563 2 FALSE 1 82 46381 0.1190 27
998 CDC42 cell division cycle 42 1p36.1 309 1736 116952 NP_001034891;NP_001782;NP_426359 NM_001039802;NM_001791;NM_044472 ENSP00000314458 P60953 TRUE can 0 0 10 Last Universal Common Ancestor 12 Cellular processes,Development,Regulation of intracellular processes and metabolism,Signal transduction chr1 22404972 22418007 |CDC42Hs|G25K| NP_001034891 10 FALSE 1 173 207119 0.0320 32
999 CDH1 cadherin 1, type 1, E-cadherin (epithelial) 16q22.1 1885 1748 192090 NP_004351 NM_004360 ENSP00000378529 P12830 TRUE cgc 0 1 0 Eukaryotes 7 Cell motility and interactions,Cellular processes,Regulation of intracellular processes and metabolism chr16 68771319 68867399 |Arc-1|CD324|CDHE|ECAD|LCAM|UVO| NP_004351 0 FALSE 5 132 75318 0.0510 20
1007 CDH9 cadherin 9, type 2 (T1-cadherin) 5p14 13021 1768 609974 NP_057363 NM_016279 ENSP00000231021 Q9ULB4 TRUE can 0 0 1 Eukaryotes 1 Cell motility and interactions chr5 26881248 26988440 |NA| NP_057363 1 FALSE 2 8 4822 0.3570 1
1008 CDH10 cadherin 10, type 2 (T2-cadherin) 5p14.2 5187 1749 604555 NP_006718 NM_001190450;NM_006727;XR_427656 ENSP00000264463 Q9Y6N8 TRUE can 0 0 0 Eukaryotes 0 Cell motility and interactions chr5 24487775 24593599 |NA| NP_006718 0 FALSE 3 6 362 0.3330 1
1009 CDH11 cadherin 11, type 2, OB-cadherin (osteoblast) 16q21 - 1750 600023 NP_001788;XP_005255818;XP_005255819;XP_005255820;XP_005255821;XP_005255823;XP_005255824 NM_001797;XM_005255761;XM_005255762;XM_005255763;XM_005255764;XM_005255766;XM_005255767 ENSP00000268603 P55287 TRUE cgc 1 0 0 Eukaryotes 4 Cell motility and interactions,Development chr16 64981509 65038772 |CAD11|CDHOB|OSF-4| NP_001788 0 FALSE 1 4 95 0.1670 1
1010 CDH12 cadherin 12, type 2 (N-cadherin 2) 5p14.3 11081 1751 600562 NP_004052 NM_004061 ENSP00000371689 P55289 TRUE can 0 0 0 Eukaryotes 3 Cell motility and interactions chr5 21751849 22078785 |CDHB| NP_004052 0 FALSE 1 2 1 0.0000 1
1016 CDH18 cadherin 18, type 2 5p14.3 4314 1757 603019 NP_001161139;NP_004925;XP_005248285;XP_006714498;XP_006714499;XP_006714500 NM_001167667;NM_004934;XM_005248228;XM_006714435;XM_006714436;XM_006714437 ENSP00000274170 Q13634 TRUE can 0 0 0 Eukaryotes 0 Cell motility and interactions chr5 19473338 19839095 |CDH14L| NP_004925 0 FALSE 1 5 7363 0.3000 1
1019 CDK4 cyclin-dependent kinase 4 12q14 447 1773 123829 NP_000066 NM_000075;NM_052984 ENSP00000257904 P11802 TRUE cgc 1 0 0 Eukaryotes 13 Cell cycle,Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism,Regulation of transcription chr12 58142311 58145500 |CMM3|PSK-J3| NP_000066 0 FALSE 2 140 104782 0.0610 26
1021 CDK6 cyclin-dependent kinase 6 7q21-q22 4533 1777 603368 NP_001138778;NP_001250;XP_006715898;XP_006715899 NM_001145306;NM_001259;XM_006715835;XM_006715836 ENSP00000265734 Q00534 TRUE cgc 1 0 0 Last Universal Common Ancestor 28 Cell cycle,Cell motility and interactions,Cellular metabolism,Cellular processes,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Regulation of transcription chr7 92244457 92462637 |PLSTIRE| NP_001138778 0 FALSE 2 109 79644 0.0480 9
1026 CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 6p21.2 298 1784 116899 NP_000380;NP_001207706;NP_001207707;NP_510867 NM_000389;NM_001220777;NM_001220778;NM_078467;NR_037150 ENSP00000244741;ENSP00000353864 P38936 TRUE can 0 0 0 Last Universal Common Ancestor 44 Cell cycle,Cell response to stimuli,Cellular metabolism,Development,Immune system response,Regulation of intracellular processes and metabolism,Signal transduction chr6 36651879 36653574 |CAP20|CDKN1|MDA-6|SDI1|WAF1|p21CIP1| NP_000380 0 FALSE 2 271 301145 0.0470 27
1027 CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 12p13.1-p12 2867 1785 600778 NP_004055 NM_004064 ENSP00000228872 P46527 TRUE can 0 0 0 Metazoans 13 Cell cycle,Cell motility and interactions,Cell response to stimuli,Cellular metabolism,Cellular processes,Development,Regulation of intracellular processes and metabolism,Signal transduction chr12 12870774 12871877 |CDKN4|MEN1B|MEN4|P27KIP1| NP_004055 0 FALSE 3 81 23389 0.1280 17
1029 CDKN2A cyclin-dependent kinase inhibitor 2A 9p21 2542 1787 600160 NP_000068;NP_001182061;NP_478102;NP_478104;XP_005251400 NM_000077;NM_001195132;NM_058195;NM_058196;NM_058197;XM_005251343 ENSP00000394932 Q8N726 TRUE cgc 0 1 0 Eukaryotes 13 Cell cycle,Cell motility and interactions,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Immune system response,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction chr9 21968727 21974826 |ARF|CMM2|INK4|INK4A|MTS-1|P14ARF|P16|P16-INK4A|P16INK4|P16INK4A|P19ARF|TP16| NP_001182061 0 FALSE 14 175 148881 0.0600 4
1030 CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) 9p21 2696 1788 600431 NP_004927;NP_511042 NM_004936;NM_078487 ENSP00000276925 P42772 TRUE can 0 0 0 Eukaryotes 3 Cell cycle,Cell response to stimuli,Cellular metabolism,Regulation of intracellular processes and metabolism,Signal transduction chr9 22005989 22008952 |INK4B|MTS2|TP15|p15INK4b| NP_004927 0 FALSE 4 18 3088 0.0390 1
1031 CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) 1p32 4534 1789 603369 NP_001253;NP_523240 NM_001262;NM_078626 ENSP00000262662 P42773 TRUE cgc 0 1 0 Last Universal Common Ancestor 1 Cell cycle,Cellular metabolism,Development,Regulation of intracellular processes and metabolism,Signal transduction chr1 51436041 51439939 |INK4C|p18-INK4C| NP_001253 0 FALSE 1 35 12203 0.0570 1
1045 CDX2 caudal type homeobox 2 13q12.3 - 1806 600297 NP_001256 NM_001265 ENSP00000231656 Q99626 TRUE cgc 1 0 0 Metazoans 10 Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription chr13 28537255 28543143 |CDX-3|CDX2/AS|CDX3| NP_001256 0 FALSE 1 15 597 0.2290
1046 CDX4 caudal type homeobox 4 Xq13.2 - 1808 300025 NP_005184 NM_005193 ENSP00000362613 O14627 TRUE can 0 0 0 Metazoans 1 Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription chrX 72667090 72674418 |NA| NP_005184 0 FALSE 1 7 94 0.0480
1050 CEBPA CCAAT/enhancer binding protein (C/EBP), alpha 19q13.1 296 1833 116897 NP_001272758;NP_001274353;NP_001274364;NP_004355 NM_001285829;NM_001287424;NM_001287435;NM_004364 ENSP00000427514 P49715 TRUE cgc 1 0 0 Metazoans 7 Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction chr19 33792247 33793422 |C/EBP-alpha| NP_001274353 0 FALSE 1 106 72020 0.0920 4
1105 CHD1 chromodomain helicase DNA binding protein 1 5q15-q21 3668 1915 602118 NP_001261;XP_005271923;XP_005271924 NM_001270;XM_005271866;XM_005271867;XR_427702 ENSP00000284049 O14646 TRUE can 0 0 0 Last Universal Common Ancestor 4 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr5 98192087 98262090 |NA| XP_005271923 0 FALSE 1 21 1980 0.1570
1106 CHD2 chromodomain helicase DNA binding protein 2 15q26 - 1917 602119 NP_001036037;NP_001262 NM_001042572;NM_001271 ENSP00000284049 O14647 TRUE can 0 0 0 Last Universal Common Ancestor 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr15 93444468 93567932 |EEOC| NP_001262 0 FALSE 2 10 957 0.0440 1
1107 CHD3 chromodomain helicase DNA binding protein 3 17p13.1 9071 1918 602120 NP_001005271;NP_001005273;NP_005843;XP_005256484;XP_005256485;XP_005256486;XP_005256488;XP_006721486;XP_006721487;XP_006721488;XP_006721489;XP_006721490;XP_006721491;XP_006721492;XP_006721493 NM_001005271;NM_001005273;NM_005852;XM_005256427;XM_005256428;XM_005256429;XM_005256431;XM_006721423;XM_006721424;XM_006721425;XM_006721426;XM_006721427;XM_006721428;XM_006721429;XM_006721430 ENSP00000369716 Q12873 TRUE can 0 0 0 Last Universal Common Ancestor 1 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr17 7788125 7815019 |Mi-2a|Mi2-ALPHA|ZFH| XP_005256484 0 FALSE 1 136 92134 0.0750 10
1108 CHD4 chromodomain helicase DNA binding protein 4 12p13 4472 1919 603277 NP_001264;XP_005253725;XP_006719021;XP_006719022;XP_006719023;XP_006719024;XP_006719025 NM_001273;XM_005253668;XM_006718958;XM_006718959;XM_006718960;XM_006718961;XM_006718962 ENSP00000349508 Q14839 TRUE can 0 0 0 Last Universal Common Ancestor 4 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr12 6680032 6715539 |CHD-4|Mi-2b|Mi2-BETA| NP_001264 0 FALSE 1 102 72654 0.1330 16
1113 CHGA chromogranin A (parathyroid secretory protein 1) 14q32 7170 1929 118910 NP_001266;XP_005267349;XP_006725223 NM_001275;XM_005267292;XM_006725160 ENSP00000216492;ENSP00000358595 P10645 TRUE can 0 0 0 Vertebrates 0 Multicellular activities chr14 93389705 93401226 |NA| NP_001266 0 FALSE 1 7 1393 0.0480
1123 CHN1 chimerin 1 2q31.1 319 1943 118423 NP_001020372;NP_001193531;NP_001813 NM_001025201;NM_001206602;NM_001822;NR_038133 ENSP00000386741 P15882 TRUE cgc 1 0 0 Eukaryotes 0 Signal transduction chr2 175664847 175809669 |ARHGAP2|DURS2|NC|RHOGAP2| NP_001813 0 FALSE 1 13 3192 0.0770
1183 CLCN4 chloride channel, voltage-sensitive 4 Xp22.3 2362 2022 302910 NP_001243873;NP_001821 NM_001256944;NM_001830 ENSP00000370213 P51793 TRUE can 0 0 2 Last Universal Common Ancestor 0 Cellular processes chrX 10153073 10201621 |CLC4|ClC-4|ClC-4A| NP_001821 2 FALSE 1
1198 CLK3 CDC-like kinase 3 15q24 4290 2071 602990 NP_001123500;NP_003983;XP_005254208;XP_005254209;XP_005254210;XP_005254211;XP_006720446;XP_006720447 NM_001130028;NM_001292;NM_003992;XM_005254151;XM_005254152;XM_005254153;XM_005254154;XM_006720383;XM_006720384 ENSP00000378505 P49761 TRUE can 0 0 0 Eukaryotes 3 Cellular metabolism,Cellular processes chr15 74907796 74922221 |PHCLK3|PHCLK3/152| XP_005254208 0 FALSE 1 51 23954 0.1000 1
1213 CLTC clathrin, heavy chain (Hc) 17q23.1 350 2092 118955 NP_001275582;NP_004850;XP_005257069 NM_001288653;NM_004859;XM_005257012 ENSP00000269122 Q00610 TRUE cgc 1 0 1 Eukaryotes 3 Cellular processes chr17 57721637 57771210 |CHC|CHC17|CLH-17|CLTCL2|Hc| XP_005257069 1 FALSE 1 161 128506 0.0740 7
1234 CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene) 3p21.31 - 1606 601373 NP_000570;NP_001093638 NM_000579;NM_001100168 ENSP00000292303 P51681 TRUE can 0 0 1 Vertebrates 0 Cell motility and interactions,Cell response to stimuli,Immune system response,Other,Regulation of intracellular processes and metabolism,Signal transduction chr3 46414394 46415449 |CC-CKR-5|CCCKR5|CCR-5|CD195|CKR-5|CKR5|CMKBR5|IDDM22| NP_000570 1 FALSE 1 43 44693 0.0610 8
1240 CMKLR1 chemokine-like receptor 1 12q24.1 3829 2121 602351 NP_001135815;NP_001135816;NP_001135817;NP_004063 NM_001142343;NM_001142344;NM_001142345;NM_004072 ENSP00000311733 Q99788 TRUE can 0 0 0 Vertebrates 0 Cell motility and interactions,Development,Signal transduction chr12 108685621 108686736 |CHEMERINR|ChemR23|DEZ|RVER1| NP_001135815 0 FALSE 1 2 1 0.0000
1262 CNGA4 cyclic nucleotide gated channel alpha 4 11p15.4 18724 2152 609472 NP_001032406;XP_005252850;XP_006718207;XP_006718208;XP_006718209 NM_001037329;XM_005252793;XM_006718144;XM_006718145;XM_006718146 ENSP00000369268 Q8IV77 TRUE can 0 0 0 Last Universal Common Ancestor 0 Cell response to stimuli,Cellular processes chr11 6260266 6265636 |CNCA2|CNG-4|CNG5|CNGB2|OCNC2|OCNCBETA|OCNCb| XP_005252850 0 FALSE 1 7
1272 CNTN1 contactin 1 12q11-q12 7189 2171 600016 NP_001242992;NP_001242993;NP_001834;NP_778203;XP_005268708;XP_006719304 NM_001256063;NM_001256064;NM_001843;NM_175038;XM_005268651;XM_006719241 ENSP00000325660 Q12860 TRUE can 0 0 0 Metazoans 0 Signal transduction chr12 41302235 41463834 |GP135|MYPCN| NP_001834 0 FALSE 1 16 5894 0.0750 3
1277 COL1A1 collagen, type I, alpha 1 17q21.33 362 2197 120150 NP_000079;XP_005257115;XP_005257116;XP_006721766 NM_000088;XM_005257058;XM_005257059;XM_006721703 ENSP00000225964 P02452 TRUE cgc 1 0 0 Eukaryotes 9 Cell response to stimuli,Cellular processes,Development chr17 48262866 48278874 |NA| NP_000079 0 FALSE 1 48 36955 0.0700 5
1278 COL1A2 collagen, type I, alpha 2 7q22.1 363 2198 120160 NP_000080 NM_000089 ENSP00000297268 P08123 TRUE can 0 0 0 Last Universal Common Ancestor 2 Cell response to stimuli,Cellular processes,Development,Signal transduction chr7 94024344 94059702 |NA| NP_000080 0 FALSE 2 30 27451 0.0990 4
1280 COL2A1 collagen, type II, alpha 1 12q13.11 361 2200 120140 NP_001835;NP_149162;XP_006719305 NM_001844;NM_033150;XM_006719242 ENSP00000369889 P02458 TRUE can 0 0 0 Last Universal Common Ancestor 3 Cell response to stimuli,Cellular processes,Development chr12 48367193 48398104 |ANFH|AOM|COL11A3|SEDC|STL1| NP_001835 0 FALSE 1 34 48775 0.0500 2
1281 COL3A1 collagen, type III, alpha 1 2q31 365 2201 120180 NP_000081 NM_000090 ENSP00000304408 P02461 TRUE can 0 0 0 Eukaryotes 4 Cell motility and interactions,Cell response to stimuli,Cellular metabolism,Cellular processes,Development,Immune system response,Multicellular activities,Regulation of transcription,Signal transduction chr2 189839216 189876497 |EDS4A| NP_000081 0 FALSE 1 16 2156 0.0580 2
1284 COL4A2 collagen, type IV, alpha 2 13q34 355 2203 120090 NP_001837 NM_001846 ENSP00000353654 P08572 TRUE can 0 0 0 Last Universal Common Ancestor 4 Cell motility and interactions,Cellular processes,Development chr13 110960251 111164535 |POREN2| NP_001837 0 FALSE 1 25 15250 0.0870 5
1289 COL5A1 collagen, type V, alpha 1 9q34.2-q34.3 368 2209 120215 NP_000084;NP_001265003 NM_000093;NM_001278074 ENSP00000360882 P20908 TRUE can 0 0 0 Eukaryotes 1 Cellular processes chr9 137534034 137734146 |NA| NP_000084 0 FALSE 1 11 3278 0.1090 3
1298 COL9A2 collagen, type IX, alpha 2 1p33-p32 373 2218 120260 NP_001843;XP_005270537;XP_006710428 NM_001852;XM_005270480;XM_006710365 ENSP00000361834 Q14055 TRUE can 0 0 0 Eukaryotes 1 Cellular processes,Development chr1 40766857 40782869 |DJ39G22.4|EDM2|STL5| NP_001843 0 FALSE 1 6 256 0.1330 6
1301 COL11A1 collagen, type XI, alpha 1 1p21 375 2186 120280 NP_001177638;NP_001845;NP_542196;NP_542197 NM_001190709;NM_001854;NM_080629;NM_080630 ENSP00000359114 P12107 TRUE can 0 0 0 Eukaryotes 1 Cell motility and interactions,Cell response to stimuli,Cellular processes,Development chr1 103343578 103573734 |CO11A1|COLL6|STL2| NP_542196 0 FALSE 3 2 9 0.0000 1
1316 KLF6 Kruppel-like factor 6 10p15 3632 2235 602053 NP_001153596;NP_001153597;NP_001291 NM_001008490;NM_001160124;NM_001160125;NM_001300;NR_027653 ENSP00000419923 Q99612 TRUE cgc 0 1 0 Eukaryotes 5 Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Immune system response,Regulation of intracellular processes and metabolism,Regulation of transcription chr10 3821734 3827206 |CBA1|COPEB|CPBP|GBF|ST12|ZF9| NP_001291 0 FALSE 1 19 12076 0.1640
1345 COX6C cytochrome c oxidase subunit VIc 8q22.2 494 2285 124090 NP_004365 NM_004374 ENSP00000297564 P09669 TRUE cgc 1 0 3 Metazoans 0 -1 chr8 100899736 100904249 |NA| NP_004365 3 FALSE 1 5 105 0.0000
1373 CPS1 carbamoyl-phosphate synthase 1, mitochondrial 2q35 1995 2323 608307 NP_001116105;NP_001116106;NP_001866 NM_001122633;NM_001122634;NM_001875 ENSP00000372812;ENSP00000402608;ENSP00000416598 P31327 TRUE can 0 0 0 Last Universal Common Ancestor 0 Cellular metabolism chr2 211421443 211542706 |CPSASE1|PHN| NP_001116105 0 FALSE 1 20 2075 0.1630
1385 CREB1 cAMP responsive element binding protein 1 2q34 - 2345 123810 NP_004370;NP_604391 NM_004379;NM_134442;XR_241289;XR_241290;XR_241292;XR_427071 ENSP00000387699 P16220 TRUE cgc 1 0 0 - 5 Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction chr2 208420360 208461779 |CREB| NP_604391 0 FALSE 1 101 59458 0.0760 5
1387 CREBBP CREB binding protein 16p13.3 2534 2348 600140 NP_001073315;NP_004371;XP_005255181;XP_005255182;XP_006720911 NM_001079846;NM_004380;XM_005255124;XM_005255125;XM_006720848 ENSP00000262367;ENSP00000263253 Q92793 TRUE cgc 1 1 0 Eukaryotes 1 Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction chr16 3777722 3929917 |KAT3A|RSTS| NP_004371 0 FALSE 4 340 420282 0.0550 43
1441 CSF3R colony stimulating factor 3 receptor (granulocyte) 1p35-p34.3 737 2439 138971 NP_000751;NP_724781;NP_758519;XP_005270549;XP_005270550;XP_005270552 NM_000760;NM_156038;NM_156039;NM_172313;XM_005270492;XM_005270493;XM_005270495 ENSP00000362195 Q99062 TRUE cgc 0 0 0 Vertebrates 0 Signal transduction chr1 36931961 36945097 |CD114|GCSFR| NP_724781 0 FALSE 1 24 16876 0.1630
1442 CSH1 chorionic somatomammotropin hormone 1 (placental lactogen) 17q24.2 8350 2440 150200 NP_001308 NM_001317;NM_022640;NM_022641 ENSP00000316416;ENSP00000376623 P0DML2 TRUE can 0 0 3 Vertebrates 0 Signal transduction chr17 61972385 61973599 |CSMT|hCS-1|hCS-A| NP_001308 3 FALSE 1 6 129 0.2000 5
1460 CSNK2B casein kinase 2, beta polypeptide 6p21.3 278 2460 115441 NP_001269314;NP_001311 NM_001282385;NM_001320 ENSP00000365025;ENSP00000382984;ENSP00000395546;ENSP00000396772;ENSP00000410942;ENSP00000413092;ENSP00000415615 P67870 TRUE can 0 0 0 Eukaryotes 0 Signal transduction chr6 31634609 31637700 |CK2B|CK2N|CSK2B|G5A| NP_001311 0 FALSE 1 242 356463 0.0310 8
1496 CTNNA2 catenin (cadherin-associated protein), alpha 2 2p12-p11.1 228 2510 114025 NP_001158355;NP_001269526;NP_001269527;NP_001269528;NP_001269529;NP_004380;XP_006712012 NM_001164883;NM_001282597;NM_001282598;NM_001282599;NM_001282600;NM_004389;XM_006711949 ENSP00000418191 P26232 TRUE can 0 0 2 Metazoans 0 -1 chr2 79878683 80874994 |CAP-R|CAPR|CT114|CTNR| NP_001269526 2 FALSE 2 6 17 0.5330 1
1499 CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 3p21 286 2514 116806 NP_001091679;NP_001091680;NP_001895;XP_005264943;XP_006713046;XP_006713047;XP_006713048 NM_001098209;NM_001098210;NM_001904;XM_005264886;XM_006712983;XM_006712984;XM_006712985 ENSP00000344456 P35222 TRUE cgc 1 0 0 Eukaryotes 9 Cell cycle,Cell motility and interactions,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Multicellular activities,Other,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction chr3 41266016 41280830 |CTNNB|MRD19|armadillo| NP_001091679 0 FALSE 13 358 820745 0.0460 74
1540 CYLD cylindromatosis (turban tumor syndrome) 16q12.1 5427 2584 605018 NP_001035814;NP_001035877;NP_056062;XP_005255869;XP_006721211;XP_006721212;XP_006721213;XP_006721214;XP_006721215 NM_001042355;NM_001042412;NM_015247;XM_005255812;XM_006721148;XM_006721149;XM_006721150;XM_006721151;XM_006721152;XR_429714 ENSP00000308928 Q9NQC7 TRUE cgc 0 1 0 Metazoans 4 Cell cycle,Cellular metabolism,Regulation of intracellular processes and metabolism,Regulation of transcription chr16 50783610 50830416 |BRSS|CDMT|CYLD1|CYLDI|EAC|MFT1|SBS|USPL2| NP_056062 0 FALSE 2 43 37057 0.1100 1
1549 CYP2A7 cytochrome P450, family 2, subfamily A, polypeptide 7 19q13.2 7453 2611 608054 NP_000755;NP_085079 NM_000764;NM_030589 ENSP00000301141;ENSP00000301146;ENSP00000332679 P20853 TRUE can 0 0 3 Last Universal Common Ancestor 0 -1 chr19 41381601 41388115 |CPA7|CYPIIA7|P450-IIA4| NP_000755 3 FALSE 1
1559 CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9 10q24 3084 2623 601130 NP_000762;XP_006717707 NM_000771;XM_006717644 ENSP00000260682 P11712 TRUE can 0 0 3 Last Universal Common Ancestor 0 -1 chr10 96698440 96748782 |CPC9|CYP2C10|CYPIIC9|P450IIC9| NP_000762 3 FALSE 1 9 4047 0.2220
1571 CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 10q26.3 11813 2631 124040 NP_000764 NM_000773 ENSP00000252945 P05181 TRUE can 0 0 0 Last Universal Common Ancestor 2 -1 chr10 135340900 135352465 |CPE1|CYP2E|P450-J|P450C2E| NP_000764 0 FALSE 1 15 20301 0.0100
1602 DACH1 dachshund family transcription factor 1 13q22 16031 2663 603803 NP_004383;NP_542937;NP_542938 NM_004392;NM_080759;NM_080760 ENSP00000304994 Q9UI36 TRUE can 0 0 0 Metazoans 1 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr13 72049274 72440907 |DACH| NP_542937 0 FALSE 1 21 2750 0.1670
1616 DAXX death-domain associated protein 6p21.3 4424 2681 603186 NP_001135441;NP_001135442;NP_001241646;NP_001341;XP_005248917;XP_005275275;XP_005275411 NM_001141969;NM_001141970;NM_001254717;NM_001350;XM_005248860;XM_005275218;XM_005275354 ENSP00000266000;ENSP00000372539;ENSP00000372681;ENSP00000394108;ENSP00000404376 Q9UER7 TRUE cgc 0 1 0 Metazoans 1 Cell cycle,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction chr6 33286523 33290691 |BING2|DAP6| NP_001135442 0 FALSE 5 111 63127 0.0760 13
1630 DCC DCC netrin 1 receptor 18q21.3 391 2701 120470 NP_005206;XP_005258261 NM_005215;XM_005258204 ENSP00000389140 P43146 TRUE can 0 0 0 Eukaryotes 3 Cell cycle,Cell motility and interactions,Development,Regulation of intracellular processes and metabolism chr18 49867158 51057020 |CRC18|CRCR1|IGDCC1|MRMV1|NTN1R1| NP_005206 0 FALSE 1 57 20673 0.0460 15
1636 ACE angiotensin I converting enzyme 17q23.3 108 2707 106180 NP_000780;NP_001171528;NP_690043;XP_005257167;XP_006721800 NM_000789;NM_001178057;NM_152830;NM_152831;XM_005257110;XM_006721737 ENSP00000290866;ENSP00000464149 P12821 TRUE can 0 0 0 Last Universal Common Ancestor 1 Cell cycle,Cell motility and interactions,Cellular metabolism,Cellular processes,Development,Multicellular activities,Regulation of intracellular processes and metabolism chr17 61554456 61574724 |ACE1|CD143|DCP|MVCD3| NP_000780 0 FALSE 1 8 534 0.1790
1639 DCTN1 dynactin 1 2p13 7206 2711 601143 NP_001128512;NP_001128513;NP_001177765;NP_001177766;NP_004073;NP_075408 NM_001135040;NM_001135041;NM_001190836;NM_001190837;NM_004082;NM_023019;NR_033935 ENSP00000354791 Q14203 TRUE can 0 0 0 Eukaryotes 0 Cell cycle,Development chr2 74588629 74605372 |DAP-150|DP-150|P135| NP_004073 0 FALSE 1 82 34805 0.0550 22
1643 DDB2 damage-specific DNA binding protein 2, 48kDa 11p12-p11 2886 2718 600811 NP_000098;XP_005252865;XP_006718224 NM_000107;XM_005252808;XM_006718161;XR_242780 ENSP00000256996 Q92466 TRUE cgc 0 1 0 Last Universal Common Ancestor 2 Cell response to stimuli,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription chr11 47236688 47260397 |DDBB|UV-DDB2| NP_000098 0 FALSE 1 48 6404 0.1770 8
1649 DDIT3 DNA-damage-inducible transcript 3 12q13.1-q13.2 529 2726 126337 NP_001181982;NP_001181983;NP_001181984;NP_001181985;NP_001181986;NP_004074 NM_001195053;NM_001195054;NM_001195055;NM_001195056;NM_001195057;NM_004083 ENSP00000234170;ENSP00000447803 P35638 TRUE cgc 1 0 0 Vertebrates 2 Cell cycle,Cell response to stimuli,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction chr12 57910595 57911258 |CHOP|CHOP-10|CHOP10|GADD153| NP_001181982 0 FALSE 1 68 56634 0.0800 1
1654 DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked Xp11.3-p11.23 2154 2745 300160 NP_001180345;NP_001180346;NP_001347 NM_001193416;NM_001193417;NM_001356;NM_024005 ENSP00000382840 O00571 TRUE can 0 0 3 Last Universal Common Ancestor 12 -1 chrX 41193506 41206969 |CAP-Rf|DBX|DDX14|DDX3| NP_001347 3 FALSE 4 136 50043 0.1520 5
1655 DDX5 DEAD (Asp-Glu-Ala-Asp) box helicase 5 17q21 1615 2746 180630 NP_004387;XP_005257168;XP_006721801 NM_004396;XM_005257111;XM_006721738;XR_429871;XR_429872 ENSP00000225792 P17844 TRUE cgc 1 0 0 Last Universal Common Ancestor 6 Cell cycle,DNA/RNA metabolism and transcription,Regulation of transcription chr17 62496044 62502237 |G17P1|HLR1|HUMP68| NP_004387 0 FALSE 1 190 80242 0.1330 8
1656 DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6 11q23.3 - 2747 600326 NP_001244120;NP_004388;XP_005271474;XP_005271475 NM_001257191;NM_004397;XM_005271417;XM_005271418 ENSP00000264018;ENSP00000469200 P26196 TRUE cgc 1 0 2 Last Universal Common Ancestor 10 -1 chr11 118625424 118656960 |HLR2| NP_001244120 2 FALSE 1 63 45583 0.0640 7
1657 DMXL1 Dmx-like 1 5q22 9294 2937 605671 NP_005500;XP_005271966;XP_005271967;XP_005271968;XP_005271969;XP_005271970;XP_006714623 NM_005509;XM_005271909;XM_005271910;XM_005271911;XM_005271912;XM_005271913;XM_006714560 ENSP00000309690 Q9Y485 TRUE can 0 0 0 Eukaryotes 5 -1 chr5 118407265 118582911 |NA| XP_005271966 0 FALSE 1
1662 DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 11q22-q23 3138 2735 601235 NP_004389 NM_004398 ENSP00000314348 Q13206 TRUE cgc 1 0 1 Last Universal Common Ancestor 5 -1 chr11 108535881 108811147 |HRH-J8| NP_004389 1 FALSE 1 5 147 0.2000
1729 DIAPH1 diaphanous-related formin 1 5q31 3670 2876 602121 NP_001073280;NP_005210;XP_005268441 NM_001079812;NM_005219;XM_005268384 ENSP00000381565 O60610 TRUE can 0 0 0 Eukaryotes 1 Cell response to stimuli,Cellular processes chr5 140896421 140998481 |DFNA1|LFHL1|hDIA1| NP_005210 0 FALSE 1 37 5659 0.0650 4
1741 DLG3 discs, large homolog 3 (Drosophila) Xq13.1 2177 2902 300189 NP_001159750;NP_065781;NP_066943;XP_005262305;XP_006724688;XP_006724689;XP_006724690 NM_001166278;NM_020730;NM_021120;XM_005262248;XM_006724625;XM_006724626;XM_006724627;XR_430518 ENSP00000363480;ENSP00000381425 Q92796 TRUE can 0 0 0 Last Universal Common Ancestor 1 Cell cycle,Regulation of intracellular processes and metabolism chrX 69665052 69722116 |MRX90|NEDLG|PPP1R82|SAP102|XLMR| NP_066943 0 FALSE 1 56 47171 0.0650 3
1756 DMD dystrophin Xp21.2 2303 2928 300377 NP_000100;NP_003997;NP_004000;NP_004001;NP_004002;NP_004003;NP_004004;NP_004005;NP_004006;NP_004007;NP_004008;NP_004009;NP_004010;NP_004011;NP_004012;NP_004013;NP_004014;XP_006724531;XP_006724532;XP_006724533;XP_006724534;XP_006724535;XP_006724536;XP_006724537;XP_006724538;XP_006724539 NM_000109;NM_004006;NM_004007;NM_004009;NM_004010;NM_004011;NM_004012;NM_004013;NM_004014;NM_004015;NM_004016;NM_004017;NM_004018;NM_004019;NM_004020;NM_004021;NM_004022;NM_004023;XM_006724468;XM_006724469;XM_006724470;XM_006724471;XM_006724472;XM_006724473;XM_006724474;XM_006724475;XM_006724476;XR_430491 ENSP00000354923 P11532 TRUE can 0 0 0 Opisthokonts 6 Cellular metabolism,Cellular processes,Development chrX 31152217 33038315 |CMD3B|DXS142|DXS164|DXS206|DXS230|DXS239|DXS268|DXS269|DXS270|DXS272| NP_003997 0 TRUE 2 38 39950 0.0650 6
1767 DNAH5 dynein, axonemal, heavy chain 5 5p15.2 4514 2950 603335 NP_001360;XP_005248319 NM_001369;XM_005248262 ENSP00000265104 Q8TE73 TRUE can 0 0 0 Eukaryotes 3 Cell motility and interactions,Cellular processes chr5 13692096 13944547 |CILD3|DNAHC5|KTGNR| NP_001360 0 TRUE 1 1 0 0.0000
1770 DNAH9 dynein, axonemal, heavy chain 9 17p12 4511 2953 603330 NP_001363;NP_004653;XP_006721528;XP_006721529;XP_006721530 NM_001372;NM_004662;XM_006721465;XM_006721466;XM_006721467 ENSP00000262442 Q9NYC9 TRUE can 0 0 0 Eukaryotes 0 Cellular processes,Development,Multicellular activities chr17 11501816 11872841 |DNAH17L|DNEL1|DYH9|Dnahc9|HL-20|HL20| NP_001363 0 FALSE 2 1 0 0.0000
1780 DYNC1I1 dynein, cytoplasmic 1, intermediate chain 1 7q21.3 4798 2963 603772 NP_001129028;NP_001129029;NP_001265350;NP_001265351;NP_004402;XP_006715933 NM_001135556;NM_001135557;NM_001278421;NM_001278422;NM_004411;XM_006715870 ENSP00000320130 O14576 TRUE can 0 0 0 Eukaryotes 1 Cellular processes chr7 95434042 95726902 |DNCI1|DNCIC1| NP_004402 0 FALSE 1 47 18643 0.0750 1
1785 DNM2 dynamin 2 19p13.2 3852 2974 602378 NP_001005360;NP_001005361;NP_001005362;NP_001177645;NP_004936 NM_001005360;NM_001005361;NM_001005362;NM_001190716;NM_004945 ENSP00000347890 P50570 TRUE cgc 0 1 2 Last Universal Common Ancestor 4 Cell cycle,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction chr19 10828919 10941720 |CMT2M|CMTDI1|CMTDIB|DI-CMTB|DYN2|DYNII|LCCS5| NP_001005360 2 FALSE 1 94 78861 0.0670 4
1786 DNMT1 DNA (cytosine-5-)-methyltransferase 1 19p13.2 532 2976 126375 NP_001124295;NP_001370;XP_006722744 NM_001130823;NM_001379;XM_006722681 ENSP00000352516 P26358 TRUE can 0 0 0 Last Universal Common Ancestor 10 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr19 10244894 10305575 |ADCADN|CXXC9|DNMT|HSN1E|MCMT| NP_001124295 0 FALSE 1 75 15325 0.1600 18
1788 DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha 2p23 4141 2978 602769 NP_072046;NP_715640;NP_783328;NP_783329;XP_005264232;XP_005264233;XP_005264234;XP_006712020;XP_006712021 NM_022552;NM_153759;NM_175629;NM_175630;XM_005264175;XM_005264176;XM_005264177;XM_006711957;XM_006711958 ENSP00000264709 Q9Y6K1 TRUE cgc 0 1 0 Last Universal Common Ancestor 11 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of transcription chr2 25457151 25536853 |DNMT3A2|M.HsaIIIA|TBRS| NP_072046 0 FALSE 1 49 8792 0.1560 10
1794 DOCK2 dedicator of cytokinesis 2 5q35.1 9121 2988 603122 NP_004937;XP_005265887 NM_004946;XM_005265830 ENSP00000256935 Q92608 TRUE can 0 0 0 Eukaryotes 0 Cell motility and interactions,Cellular processes,Immune system response chr5 169064331 169509859 |NA| NP_004937 0 FALSE 2 23 5355 0.0790 2
1804 DPP6 dipeptidyl-peptidase 6 7q36.2 525 3010 126141 NP_001034439;NP_001927;NP_570629;XP_006715934;XP_006715935 NM_001039350;NM_001936;NM_130797;XM_006715871;XM_006715872 ENSP00000367001 P42658 TRUE can 0 0 0 Last Universal Common Ancestor 0 Cellular metabolism chr7 153749906 154684187 |DPPX|VF2| NP_570629 0 FALSE 2 3 73 0.0000
1806 DPYD dihydropyrimidine dehydrogenase 1p22 2036 3012 612779 NP_000101;NP_001153773;XP_005270619;XP_006710460 NM_000110;NM_001160301;XM_005270562;XM_006710397 ENSP00000359211 Q12882 TRUE can 0 0 0 Last Universal Common Ancestor 3 Cellular metabolism,DNA/RNA metabolism and transcription chr1 97544535 98386478 |DHPDHASE|DPD| NP_000101 0 FALSE 1 3 124 0.0000
1811 SLC26A3 solute carrier family 26 (anion exchanger), member 3 7q31 544 3018 126650 NP_000102;XP_006715936 NM_000111;XM_006715873 ENSP00000345873 P40879 TRUE can 0 0 0 Last Universal Common Ancestor 4 Cellular processes chr7 107408021 107434954 |CLD|DRA| NP_000102 0 FALSE 1 2 2 0.0000
1816 DRD5 dopamine receptor D5 4p16.1 542 3026 126453 NP_000789 NM_000798 ENSP00000306129 P21918 TRUE can 0 0 2 Metazoans 1 Cell response to stimuli,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Signal transduction chr4 9783654 9785084 |DBDR|DRD1B|DRD1L2| NP_000789 2 FALSE 1 5 64 0.1000 2
1823 DSC1 desmocollin 1 18q12.1 511 3035 125643 NP_004939;NP_077739 NM_004948;NM_024421 ENSP00000257198;ENSP00000320768;ENSP00000353608 Q08554 TRUE can 0 0 0 Eukaryotes 1 Cell motility and interactions chr18 28710480 28742557 |CDHF1|DG2/DG3| NP_077739 0 FALSE 1 21 1025 0.1670
1825 DSC3 desmocollin 3 18q12.1 2604 3037 600271 NP_001932;NP_077741 NM_001941;NM_024423 ENSP00000257198;ENSP00000320768;ENSP00000353608 Q14574 TRUE can 0 0 0 Eukaryotes 2 Cell motility and interactions chr18 28574144 28622626 |CDHF3|DSC|DSC4|HT-CP| NP_001932 0 FALSE 1 7 147 0.1900
1828 DSG1 desmoglein 1 18q12.1 515 3048 125670 NP_001933 NM_001942 ENSP00000257192 Q02413 TRUE can 0 0 0 Eukaryotes 1 Cell motility and interactions,Cellular processes chr18 28898264 28935306 |CDHF4|DG1|DSG|EPKHE|EPKHIA|PPKS1|SPPK1| NP_001933 0 FALSE 1 25 2367 0.1230
1837 DTNA dystrobrevin, alpha 18q12 3141 3057 601239 NP_001121647;NP_001185867;NP_001185868;NP_001185869;NP_001185870;NP_001185871;NP_001185872;NP_001185873;NP_001185874;NP_001381;NP_001382;NP_001383;NP_116757;NP_116760;NP_116761;NP_116762;NP_116763;XP_005258264;XP_005258269;XP_005258273;XP_005258274;XP_005258275;XP_005258276;XP_005258277;XP_005258278;XP_005258279;XP_005258280;XP_005258281;XP_006722458;XP_006722459;XP_006722460;XP_006722461;XP_006722462;XP_006722463;XP_006722464;XP_006722465;XP_006722466;XP_006722467;XP_006722468;XP_006722469;XP_006722470;XP_006722471;XP_006722472;XP_006722473;XP_006722474;XP_006722475;XP_006722476;XP_006722477;XP_006722478 NM_001128175;NM_001198938;NM_001198939;NM_001198940;NM_001198941;NM_001198942;NM_001198943;NM_001198944;NM_001198945;NM_001390;NM_001391;NM_001392;NM_032975;NM_032978;NM_032979;NM_032980;NM_032981;XM_005258207;XM_005258212;XM_005258216;XM_005258217;XM_005258218;XM_005258219;XM_005258220;XM_005258221;XM_005258222;XM_005258223;XM_005258224;XM_006722395;XM_006722396;XM_006722397;XM_006722398;XM_006722399;XM_006722400;XM_006722401;XM_006722402;XM_006722403;XM_006722404;XM_006722405;XM_006722406;XM_006722407;XM_006722408;XM_006722409;XM_006722410;XM_006722411;XM_006722412;XM_006722413;XM_006722414;XM_006722415 ENSP00000382064 Q9Y4J8 TRUE can 0 0 0 Metazoans 0 Multicellular activities,Signal transduction chr18 32335941 32470401 |D18S892E|DTN|DTN-A|LVNC1| XP_005258264 0 FALSE 1 25 9431 0.0830 3
1844 DUSP2 dual specificity phosphatase 2 2q11 4348 3068 603068 NP_004409 NM_004418 ENSP00000288943 Q05923 TRUE can 0 0 0 Last Universal Common Ancestor 6 Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism,Signal transduction chr2 96809565 96811093 |NA| NP_004409 0 FALSE 1 3 5 0.6670
1849 DUSP7 dual specificity phosphatase 7 3p21 4125 3073 602749 NP_001938 NM_001947 ENSP00000417183 Q16829 TRUE can 0 0 0 Last Universal Common Ancestor 1 Cellular metabolism,Cellular processes chr3 52084834 52090382 |PYST2| NP_001938 0 FALSE 1 7 524 0.1900
1852 DUSP9 dual specificity phosphatase 9 Xq28 2136 3076 300134 NP_001386;XP_005274712 NM_001395;XM_005274655 ENSP00000345853;ENSP00000472478 Q99956 TRUE can 0 0 0 Last Universal Common Ancestor 1 Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism,Signal transduction chrX 152913408 152915757 |MKP-4|MKP4| NP_001386 0 FALSE 1 9 306 0.2780
1879 EBF1 early B-cell factor 1 5q34 1256 3126 164343 NP_076870;XP_005265889;XP_005265890;XP_005265891;XP_006714890 NM_024007;XM_005265832;XM_005265833;XM_005265834;XM_006714827 ENSP00000322898 Q9UH73 TRUE cgc 1 0 1 Metazoans 1 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr5 158134988 158526486 |COE1|EBF|O/E-1| XP_005265889 1 FALSE 2 7 158 0.0950 1
1880 GPR183 G protein-coupled receptor 183 13q32.3 12040 3128 605741 NP_004942 NM_004951 ENSP00000365596 P32249 TRUE can 0 0 0 Vertebrates 1 Signal transduction chr13 99947317 99948399 |EBI2| NP_004942 0 FALSE 1 1 0 0.0000
1910 EDNRB endothelin receptor type B 13q22 8834 3180 131244 NP_000106;NP_001116131;NP_001188326;NP_003982;XP_005266332 NM_000115;NM_001122659;NM_001201397;NM_003991;NR_047024;XM_005266275 ENSP00000366416 P24530 TRUE can 0 0 0 Metazoans 0 Cell cycle,Cell motility and interactions,Cell response to stimuli,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Signal transduction chr13 78472338 78493750 |ABCDS|ET-B|ET-BR|ETB|ETBR|ETRB|HSCR|HSCR2|WS4A| NP_001188326 0 FALSE 1 9 2930 0.0560 3
1912 PHC2 polyhomeotic homolog 2 (Drosophila) 1p34.3 10340 3183 602979 NP_004418;NP_932157;XP_005270625;XP_005270627;XP_005270628;XP_005270629;XP_006710464;XP_006710465;XP_006710466 NM_004427;NM_198040;XM_005270568;XM_005270570;XM_005270571;XM_005270572;XM_006710401;XM_006710402;XM_006710403 ENSP00000257118 Q8IXK0 TRUE can 0 0 0 Metazoans 9 -1 chr1 33790469 33841140 |EDR2| NP_932157 0 FALSE 1 81 54659 0.0610 7
1956 EGFR epidermal growth factor receptor 7p12 579 3236 131550 NP_005219;NP_958439;NP_958440;NP_958441 NM_005228;NM_201282;NM_201283;NM_201284 ENSP00000275493 P00533 TRUE cgc 1 0 0 Metazoans 21 Cell cycle,Cell motility and interactions,Cellular metabolism,Cellular processes,Development,Regulation of intracellular processes and metabolism,Signal transduction chr7 55086971 55273307 |ERBB|ERBB1|HER1|PIG61|mENA| NP_005219 0 FALSE 4 867 2449691 0.0170 76
1959 EGR2 early growth response 2 10q21.1 551 3239 129010 NP_000390;NP_001129649;NP_001129650;NP_001129651;XP_005269647 NM_000399;NM_001136177;NM_001136178;NM_001136179;XM_005269590 ENSP00000242480 P11161 TRUE can 0 0 0 Eukaryotes 7 Cell response to stimuli,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Regulation of transcription chr10 64572970 64578399 |AT591|CMT1D|KROX20| XP_005269647 0 FALSE 1 17 1194 0.0150
1964 EIF1AX eukaryotic translation initiation factor 1A, X-linked Xp22.12 2174 3250 300186 NP_001403 NM_001412 ENSP00000368927 P47813 TRUE can 0 0 2 Last Universal Common Ancestor 1 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of transcription chr1 17012119 17012550 |EIF4C|eIF-1A| NP_001403 2 FALSE 1 18 3419 0.0980 8
1974 EIF4A2 eukaryotic translation initiation factor 4A2 3q28 3062 3284 601102 NP_001958 NM_001967 ENSP00000326381 Q14240 TRUE cgc 1 0 11 Last Universal Common Ancestor 2 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr3 186502219 186507055 |BM-010|DDX2B|eIF-4A-II|eIF4A-II| NP_001958 11 FALSE 1 62 30886 0.0620 9
1993 ELAVL2 ELAV like neuron-specific RNA binding protein 2 9p21 3396 3313 601673 NP_001164666;NP_001164668;NP_004423;XP_005251447;XP_005251448;XP_005251449;XP_005251450;XP_005251451;XP_005251452;XP_006716796;XP_006716797;XP_006716798;XP_006716799;XP_006716800;XP_006716801 NM_001171195;NM_001171197;NM_004432;XM_005251390;XM_005251391;XM_005251392;XM_005251393;XM_005251394;XM_005251395;XM_006716733;XM_006716734;XM_006716735;XM_006716736;XM_006716737;XM_006716738 ENSP00000369460 Q12926 TRUE can 0 0 2 Eukaryotes 4 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr9 23692558 23765099 |HEL-N1|HELN1|HUB| XP_005251447 2 FALSE 1 11 2069 0.1820 1
1999 ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific ) 1q32.2 3722 3318 602191 NP_001107781;NP_004424;XP_005244999 NM_001114309;NM_004433;XM_005244942 ENSP00000352673 P78545 TRUE can 0 0 0 Metazoans 6 Cell motility and interactions,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Immune system response,Regulation of intracellular processes and metabolism,Regulation of transcription chr1 201980265 201984448 |ERT|ESE-1|ESX| NP_001107781 0 FALSE 3 46 16423 0.0650
2000 ELF4 E74-like factor 4 (ets domain transcription factor) Xq26 6499 3319 300775 NP_001120669;NP_001412;XP_005262446 NM_001127197;NM_001421;XM_005262389 ENSP00000311280 Q99607 TRUE cgc 1 0 0 Metazoans 4 Cellular metabolism,DNA/RNA metabolism and transcription,Immune system response,Regulation of intracellular processes and metabolism,Regulation of transcription chrX 129200699 129215304 |ELFR| NP_001120669 0 FALSE 1 10 176 0.0670
2005 ELK4 ELK4, ETS-domain protein (SRF accessory protein 1) 1q32 2592 3326 600246 NP_001964;NP_068567;XP_005245007;XP_005245008 NM_001973;NM_021795;XM_005244950;XM_005244951;XR_426764;XR_426765;XR_426766;XR_426767 ENSP00000350681 P28324 TRUE cgc 1 0 0 Metazoans 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr1 205585677 205593010 |NA| NP_001964 0 FALSE 1 12 1362 0.0910 2
2006 ELN elastin 7q11.23 556 3327 130160 NP_000492;NP_001075221;NP_001075222;NP_001075223;NP_001075224;NP_001265841;NP_001265842;NP_001265843;NP_001265844;NP_001265845;NP_001265846;NP_001265847;NP_001265868;XP_005250244;XP_005250245;XP_006715937;XP_006715938;XP_006715939;XP_006715940;XP_006715941 NM_000501;NM_001081752;NM_001081753;NM_001081754;NM_001081755;NM_001278912;NM_001278913;NM_001278914;NM_001278915;NM_001278916;NM_001278917;NM_001278918;NM_001278939;XM_005250187;XM_005250188;XM_006715874;XM_006715875;XM_006715876;XM_006715877;XM_006715878 ENSP00000252034;ENSP00000461753 P15502 TRUE cgc 1 0 0 Mammals 0 DNA/RNA metabolism and transcription,Development,Multicellular activities chr7 73449693 73483027 |SVAS| NP_001265868 0 FALSE 2 23 8178 0.0550 1
2033 EP300 E1A binding protein p300 22q13.2 4078 3373 602700 NP_001420;XP_006724228 NM_001429;XM_006724165 ENSP00000262367;ENSP00000263253 Q09472 TRUE cgc 0 1 0 Eukaryotes 11 Cell cycle,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction chr22 41489009 41574957 |KAT3B|RSTS2|p300| NP_001420 0 FALSE 7 476 916117 0.0410 46
2041 EPHA1 EPH receptor A1 7q34 1554 3385 179610 NP_005223;XP_006715942;XP_006715943 NM_005232;XM_006715879;XM_006715880;XR_428169 ENSP00000275815 P21709 TRUE can 0 0 0 Last Universal Common Ancestor 1 Cellular metabolism,Cellular processes,Signal transduction chr7 143088553 143105898 |EPH|EPHT|EPHT1| NP_005223 0 FALSE 1 7 224 0.3810 5
2042 EPHA3 EPH receptor A3 3p11.2 1555 3387 179611 NP_005224;NP_872585;XP_005264772;XP_005264773 NM_005233;NM_182644;XM_005264715;XM_005264716 ENSP00000337451 P29320 TRUE can 0 0 0 Last Universal Common Ancestor 0 Cellular metabolism,Cellular processes,Signal transduction chr3 89156899 89528649 |EK4|ETK1|HEK|HEK4| NP_005224 0 FALSE 1 21 24682 0.1100 5
2044 EPHA5 EPH receptor A5 4q13.1 2474 3389 600004 NP_001268694;NP_001268695;NP_001268696;NP_004430;NP_872272;XP_005265710 NM_001281765;NM_001281766;NM_001281767;NM_004439;NM_182472;XM_005265653 ENSP00000273854 P54756 TRUE can 0 0 0 Last Universal Common Ancestor 2 Cellular metabolism,Cellular processes,Signal transduction chr4 66189835 66535460 |CEK7|EHK-1|EK7|HEK7| NP_001268694 0 FALSE 2 7 662 0.0000 5
2045 EPHA7 EPH receptor A7 6q16.1 3721 3390 602190 NP_001275558;NP_001275559;NP_004431;XP_005248726;XP_005248728;XP_006715432 NM_001288629;NM_001288630;NM_004440;XM_005248669;XM_005248671;XM_006715369 ENSP00000358309 Q15375 TRUE can 0 0 0 Last Universal Common Ancestor 3 Cellular metabolism,Cellular processes,Signal transduction chr6 93953147 94129059 |EHK-3|EHK3|EK11|HEK11| NP_004431 0 FALSE 3 11 4148 0.1820 5
2047 EPHB1 EPH receptor B1 3q21-q23 2790 3392 600600 NP_004432 NM_004441 ENSP00000381097 P54762 TRUE can 0 0 0 Eukaryotes 0 Cellular metabolism,Cellular processes,Development,Signal transduction chr3 134514474 134977959 |EPHT2|Hek6| NP_004432 0 FALSE 1 18 1768 0.1370 22
2050 EPHB4 EPH receptor B4 7q22 2481 3395 600011 NP_004435 NM_004444 ENSP00000350896 P54760 TRUE can 0 0 0 Eukaryotes 1 Cellular metabolism,Cellular processes,Development,Signal transduction chr7 100401086 100424652 |HTK|MYK1|TYRO11| NP_004435 0 FALSE 1 7 2628 0.0950 22
2060 EPS15 epidermal growth factor receptor pathway substrate 15 1p32 8968 3419 600051 NP_001153441;NP_001972;XP_005270675;XP_006710509 NM_001159969;NM_001981;XM_005270618;XM_006710446 ENSP00000360798 P42566 TRUE cgc 1 0 0 Eukaryotes 0 Cellular processes,Signal transduction chr1 51822375 51946995 |AF-1P|AF1P|MLLT5| NP_001972 0 FALSE 1 114 84393 0.0800 9
2064 ERBB2 v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2 17q12 1281 3430 164870 NP_001005862;NP_004439;XP_005257197;XP_006721828;XP_006721829;XP_006721830;XP_006721831 NM_001005862;NM_004448;XM_005257140;XM_006721765;XM_006721766;XM_006721767;XM_006721768 ENSP00000269571;ENSP00000448818 P04626 TRUE cgc 1 0 0 Metazoans 15 Cell cycle,Cell motility and interactions,Cellular metabolism,Cellular processes,Development,Immune system response,Multicellular activities,Regulation of intracellular processes and metabolism,Signal transduction chr17 37856492 37884294 |CD340|HER-2|HER-2/neu|HER2|MLN 19|NGL|TKR1| NP_004439 0 FALSE 7 190 209833 0.0560 30
2065 ERBB3 v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3 12q13 1820 3431 190151 NP_001005915;NP_001973 NM_001005915;NM_001982 ENSP00000267101 P21860 TRUE can 0 0 0 Metazoans 6 Cell cycle,Cell motility and interactions,Cellular metabolism,Cellular processes,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Signal transduction chr12 56474085 56495836 |ErbB-3|HER3|LCCS2|MDA-BF-1|c-erbB-3|c-erbB3|erbB3-S|p180-ErbB3|p45-sErbB3|p85-sErbB3| NP_001973 0 FALSE 5 75 32527 0.1640 16
2066 ERBB4 v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 4 2q33.3-q34 2767 3432 600543 NP_001036064;NP_005226;XP_005246432;XP_005246433;XP_005246434;XP_006712427 NM_001042599;NM_005235;XM_005246375;XM_005246376;XM_005246377;XM_006712364 ENSP00000342235 Q15303 TRUE can 0 0 0 Metazoans 4 Cellular metabolism,Cellular processes,Signal transduction chr2 212248343 213403254 |HER4|p180erbB4| NP_005226 0 FALSE 3 62 47818 0.1150 30
2068 ERCC2 excision repair cross-complementation group 2 19q13.3 530 3434 126340 NP_000391;NP_001124339;XP_005258696 NM_000400;NM_001130867;XM_005258639 ENSP00000375809 P18074 TRUE cgc 0 1 0 Last Universal Common Ancestor 0 Cell cycle,Cell response to stimuli,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription chr19 45854890 45873489 |COFS2|EM9|XPD| NP_000391 0 FALSE 3 32 8483 0.1530 26
2070 EYA4 EYA transcriptional coactivator and phosphatase 4 6q23 4648 3522 603550 NP_004091;NP_742101;NP_742103;XP_005266907;XP_005266908;XP_005266909;XP_005266910;XP_006715436 NM_004100;NM_172103;NM_172104;NM_172105;XM_005266850;XM_005266851;XM_005266852;XM_005266853;XM_006715373 ENSP00000347294 O95677 TRUE can 0 0 0 Eukaryotes 12 Cell response to stimuli,Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr6 133595919 133849940 |CMD1J|DFNA10| XP_005266907 0 FALSE 1 1 0 0.0000
2071 ERCC3 excision repair cross-complementation group 3 2q21 593 3435 133510 NP_000113;XP_005263675 NM_000122;XM_005263618 ENSP00000285398 P19447 TRUE cgc 0 1 0 Last Universal Common Ancestor 2 Cell cycle,Cell response to stimuli,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription chr2 128015175 128051295 |GTF2H|RAD25|XPB| NP_000113 0 FALSE 1 45 24097 0.1420 29
2072 ERCC4 excision repair cross-complementation group 4 16p13.12 594 3436 133520 NP_005227 NM_005236;XR_243267;XR_429638 ENSP00000310520 Q92889 TRUE cgc 0 1 0 Last Universal Common Ancestor 1 Cell response to stimuli,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr16 14014023 14042201 |ERCC11|FANCQ|XPF| NP_005227 0 FALSE 1 20 955 0.1470 10
2073 ERCC5 excision repair cross-complementation group 5 13q33 595 3437 133530 NP_000114 NM_000123 ENSP00000347978 P28715 TRUE cgc 0 1 0 Last Universal Common Ancestor 3 Cell cycle,Cell response to stimuli,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism chr13 103459618 103528250 |COFS3|ERCC5-201|ERCM2|UVDR|XPG|XPGC| NP_001191354 0 FALSE 1 15 694 0.2290 4
2074 ERCC6 excision repair cross-complementation group 6 10q11.23 596 3438 609413 NP_000115 NM_000124 ENSP00000387966 Q03468 TRUE can 0 0 0 Eukaryotes 0 Cell response to stimuli,Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr10 50666864 50741010 |ARMD5|CKN2|COFS|COFS1|RAD26|UVSS1| NP_000115 0 FALSE 1 41 4985 0.1940 1
2077 ERF Ets2 repressor factor 19q13 9942 3444 611888 NP_006485;XP_005258700;XP_005258701;XP_006723142;XP_006723143 NM_006494;XM_005258643;XM_005258644;XM_006723079;XM_006723080 ENSP00000222329;ENSP00000353741 P50548 TRUE can 0 0 0 Last Universal Common Ancestor 3 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr19 42752620 42755493 |CRS4|PE-2|PE2| XP_005258700 0 FALSE 1 6 139 0.1330
2078 ERG v-ets avian erythroblastosis virus E26 oncogene homolog 21q22.3 1298 3446 165080 NP_001129626;NP_001129627;NP_001230357;NP_001230358;NP_001230361;NP_004440;NP_891548 NM_001136154;NM_001136155;NM_001243428;NM_001243429;NM_001243432;NM_001243433;NM_004449;NM_182918 ENSP00000381891 P11308 TRUE cgc 1 0 0 Metazoans 2 Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction chr21 39755328 39947624 |erg-3| NP_001129626 0 FALSE 2 85 13468 0.1080 3
2099 ESR1 estrogen receptor 1 6q25.1 589 3467 133430 NP_000116;NP_001116212;NP_001116213;NP_001116214;XP_006715437;XP_006715438 NM_000125;NM_001122740;NM_001122741;NM_001122742;XM_006715374;XM_006715375 ENSP00000206249;ENSP00000343925 P03372 TRUE can 0 0 0 Eukaryotes 18 Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction chr6 152129048 152420098 |ESR|ESRA|ESTRR|Era|NR3A1| NP_000116 0 FALSE 2 621 959803 0.0420 15
2113 ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1 11q23.3 1260 3488 164720 NP_001137292;NP_001155894;NP_005229;XP_005271485 NM_001143820;NM_001162422;NM_005238;XM_005271428 ENSP00000376436 P14921 TRUE can 0 0 0 Metazoans 9 Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Regulation of transcription chr11 128332259 128443025 |ETS-1| NP_001137292 0 FALSE 1 97 122471 0.0690 1
2115 ETV1 ets variant 1 7p21.3 2765 3490 600541 NP_001156619;NP_001156620;NP_001156621;NP_001156622;NP_001156623;NP_001156624;NP_004947;XP_005249692;XP_005249693 NM_001163147;NM_001163148;NM_001163149;NM_001163150;NM_001163151;NM_001163152;NM_004956;XM_005249635;XM_005249636 ENSP00000385551 P50549 TRUE cgc 1 0 0 Metazoans 1 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr7 13935494 14028677 |ER81| NP_004947 0 FALSE 1 20 1312 0.2000
2118 ETV4 ets variant 4 17q21 2833 3493 600711 NP_001073143;NP_001248366;NP_001248367;NP_001248368;NP_001977 NM_001079675;NM_001261437;NM_001261438;NM_001261439;NM_001986 ENSP00000321835 P43268 TRUE cgc 1 0 0 Vertebrates 1 Cell cycle,Cell motility and interactions,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription chr17 41605890 41622985 |E1A-F|E1AF|PEA3|PEAS3| NP_001073143 0 FALSE 1 14 2588 0.1320 1
2119 ETV5 ets variant 5 3q28 9035 3494 601600 NP_004445 NM_004454 ENSP00000306894 P41161 TRUE cgc 1 0 0 Metazoans 1 Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription chr3 185766431 185823657 |ERM| NP_004445 0 FALSE 1 17 40446 0.0150
2120 ETV6 ets variant 6 12p13 15976 3495 600618 NP_001978 NM_001987 ENSP00000379658 P41212 TRUE cgc 1 0 0 Metazoans 1 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr12 11905384 12043977 |TEL|TEL/ABL| NP_001978 0 FALSE 2 27 5972 0.1000 2
2122 MECOM MDS1 and EVI1 complex locus 3q26.2 1310 3498 165215 NP_001098547;NP_001098548;NP_001157471;NP_001157472;NP_001192123;NP_004982;NP_005232;XP_005247270;XP_005247271;XP_005247272;XP_005247273;XP_005247276;XP_005247277;XP_005247278;XP_005247280;XP_005247281;XP_005247282;XP_005247283;XP_006713599;XP_006713600 NM_001105077;NM_001105078;NM_001163999;NM_001164000;NM_001205194;NM_004991;NM_005241;XM_005247213;XM_005247214;XM_005247215;XM_005247216;XM_005247219;XM_005247220;XM_005247221;XM_005247223;XM_005247224;XM_005247225;XM_005247226;XM_006713536;XM_006713537 ENSP00000264674 Q03112 TRUE cgc 1 0 0 Eukaryotes 0 -1 chr3 168802700 169099322 |EVI1|MDS1|MDS1-EVI1|PRDM3| XP_005247270 0 FALSE 2 28 4782 0.2620
2125 EVPL envoplakin 17q25 3352 3503 601590 NP_001979 NM_001988 ENSP00000301607 Q92817 TRUE can 0 0 0 Eukaryotes 0 Cellular metabolism,Cellular processes,Development chr17 74003187 74023279 |EVPK| NP_001979 0 FALSE 1 18 15819 0.1310
2130 EWSR1 EWS RNA-binding protein 1 22q12.2 592 3508 133450 NP_001156757;NP_001156758;NP_001156759;NP_005234;NP_053733;XP_005261446;XP_005261447;XP_006724229;XP_006724230 NM_001163285;NM_001163286;NM_001163287;NM_005243;NM_013986;XM_005261389;XM_005261390;XM_006724166;XM_006724167;XR_430403 ENSP00000400142 Q01844 TRUE cgc 1 0 1 Eukaryotes 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr22 29668370 29696148 |EWS|bK984G1.4| XP_005261446 1 FALSE 1 234 515857 0.0360 8
2131 EXT1 exostosin glycosyltransferase 1 8q24.11 - 3512 608177 NP_000118 NM_000127 ENSP00000367446 Q16394 TRUE cgc 0 1 0 Eukaryotes 1 Cell cycle,Cellular metabolism,Development,Regulation of intracellular processes and metabolism,Signal transduction chr8 118811954 119123285 |EXT|TRPS2|TTV| NP_000118 0 FALSE 1 5 30 0.2000
2132 EXT2 exostosin glycosyltransferase 2 11p12-p11 599 3513 608210 NP_000392;NP_001171554;NP_997005 NM_000401;NM_001178083;NM_207122 ENSP00000379032 Q93063 TRUE cgc 0 1 0 Eukaryotes 1 Cell cycle,Cellular metabolism,Development,Regulation of intracellular processes and metabolism,Signal transduction chr11 44117803 44265834 |SOTV| NP_000392 0 FALSE 2 20 21623 0.0370
2146 EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit 7q35-q36 3342 3527 601573 NP_001190176;NP_001190177;NP_001190178;NP_004447;NP_694543;XP_005250019;XP_005250020;XP_005250021;XP_006715946;XP_006715947;XP_006715948;XP_006715949;XP_006715950 NM_001203247;NM_001203248;NM_001203249;NM_004456;NM_152998;XM_005249962;XM_005249963;XM_005249964;XM_006715883;XM_006715884;XM_006715885;XM_006715886;XM_006715887 ENSP00000320147;ENSP00000404658 Q15910 TRUE cgc 0 1 0 Last Universal Common Ancestor 15 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr7 148504741 148544399 |ENX-1|ENX1|EZH2b|KMT6|KMT6A|WVS|WVS2| XP_005250019 0 FALSE 2 239 148277 0.0480 16
2153 F5 coagulation factor V (proaccelerin, labile factor) 1q23 - 3542 612309 NP_000121 NM_000130 ENSP00000356771 P12259 TRUE can 0 0 0 Metazoans 1 Multicellular activities chr1 169483554 169555624 |FVL|PCCF|RPRGL1|THPH2| NP_000121 0 FALSE 1 12 2528 0.0910 1
2157 F8 coagulation factor VIII, procoagulant component Xq28 2384 3546 300841 NP_000123;NP_063916 NM_000132;NM_019863 ENSP00000353393;ENSP00000470549;ENSP00000471364 P00451 TRUE can 0 0 0 Eukaryotes 0 Cell response to stimuli,Immune system response,Multicellular activities chrX 154065875 154250827 |AHF|DXS1253E|F8B|F8C|FVIII|HEMA| NP_000123 0 FALSE 1 17 9300 0.1030 3
2175 FANCA Fanconi anemia, complementation group A 16q24.3 6186 3582 607139 NP_000126;NP_001018122;NP_001273096;XP_005256351;XP_006721230;XP_006721231 NM_000135;NM_001018112;NM_001286167;XM_005256294;XM_006721167;XM_006721168 ENSP00000373952 O15360 TRUE cgc 0 1 0 Metazoans 1 DNA/RNA metabolism and transcription chr16 89805165 89883023 |FA-H|FAA|FACA|FANCH| XP_005256351 0 FALSE 2 73 51891 0.0860 17
2176 FANCC Fanconi anemia, complementation group C 9q22.3 1967 3584 613899 NP_000127;NP_001230672;NP_001230673;XP_005251859;XP_006717064;XP_006717065;XP_006717066;XP_006717067 NM_000136;NM_001243743;NM_001243744;XM_005251802;XM_006717001;XM_006717002;XM_006717003;XM_006717004 ENSP00000289081 Q00597 TRUE cgc 0 1 0 Vertebrates 1 DNA/RNA metabolism and transcription chr9 97863992 98011573 |FA3|FAC|FACC| NP_000127 0 FALSE 1 56 17650 0.0890 14
2177 FANCD2 Fanconi anemia, complementation group D2 3p26 1968 3585 613984 NP_001018125;NP_149075;XP_005265003;XP_005265004;XP_006713084;XP_006713085;XP_006713086;XP_006713087;XP_006713088 NM_001018115;NM_033084;XM_005264946;XM_005264947;XM_006713021;XM_006713022;XM_006713023;XM_006713024;XM_006713025 ENSP00000287647 Q9BXW9 TRUE cgc 0 1 0 Eukaryotes 1 Cell response to stimuli,DNA/RNA metabolism and transcription chr3 10070342 10140631 |FA-D2|FA4|FAD2| NP_149075 0 FALSE 1 46 12202 0.1540 4
2178 FANCE Fanconi anemia, complementation group E 6p22-p21 2943 3586 613976 NP_068741;XP_005248942;XP_005248943;XP_005248944;XP_005248945 NM_021922;XM_005248885;XM_005248886;XM_005248887;XM_005248888 ENSP00000229769 Q9HB96 TRUE cgc 0 1 0 Vertebrates 1 DNA/RNA metabolism and transcription chr6 35420323 35434119 |NA| NP_068741 0 FALSE 1 13 1646 0.4490 13
2181 ACSL3 acyl-CoA synthetase long-chain family member 3 2q34-q35 - 3570 602371 NP_004448;NP_976251 NM_004457;NM_203372 ENSP00000350012 O95573 TRUE cgc 1 0 0 Last Universal Common Ancestor 4 Cellular metabolism chr2 223773491 223806369 |FACL3|PRO2194| NP_004448 0 FALSE 1 18 2571 0.1310
2185 PTK2B protein tyrosine kinase 2 beta 8p21.1 3131 9612 601212 NP_004094;NP_775266;NP_775267;NP_775268;XP_005273504;XP_005273505 NM_004103;NM_173174;NM_173175;NM_173176;XM_005273447;XM_005273448 ENSP00000332816 Q14289 TRUE can 0 0 0 Eukaryotes 2 Cell cycle,Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism,Signal transduction chr8 27255102 27316023 |CADTK|CAKB|FADK2|FAK2|PTK|PYK2|RAFTK| NP_004094 0 FALSE 1 88 48427 0.1300 9
2186 BPTF bromodomain PHD finger transcription factor 17q24.3 3490 3581 601819 NP_004450;NP_872579;XP_005257207;XP_005257208;XP_005257209;XP_005257210;XP_005257211;XP_005257212;XP_005257213;XP_005257214;XP_005257215;XP_005257216;XP_005257217;XP_005257218;XP_005257219;XP_006721833;XP_006721834 NM_004459;NM_182641;XM_005257150;XM_005257151;XM_005257152;XM_005257153;XM_005257154;XM_005257155;XM_005257156;XM_005257157;XM_005257158;XM_005257159;XM_005257160;XM_005257161;XM_005257162;XM_006721770;XM_006721771 ENSP00000307208;ENSP00000461014 Q12830 TRUE can 0 0 0 Eukaryotes 1 Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription chr17 65821841 65978401 |FAC1|FALZ|NURF301| XP_005257207 0 FALSE 2 24 1348 0.2140 2
2188 FANCF Fanconi anemia, complementation group F 11p15 - 3587 613897 NP_073562 NM_022725 ENSP00000330875 Q9NPI8 TRUE cgc 0 1 0 Vertebrates 0 DNA/RNA metabolism and transcription chr11 22646235 22647356 |NA| NP_073562 0 FALSE 1 14 300 0.4180 15
2189 FANCG Fanconi anemia, complementation group G 9p13 4262 3588 602956 NP_004620 NM_004629 ENSP00000367910 O15287 TRUE cgc 0 1 0 Vertebrates 2 Cell cycle,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Signal transduction chr9 35074108 35079521 |FAG|XRCC9| NP_004620 0 FALSE 1 41 35556 0.1170 15
2195 FAT1 FAT atypical cadherin 1 4q35 2986 3595 600976 NP_005236;XP_005262891;XP_005262892;XP_006714202 NM_005245;XM_005262834;XM_005262835;XM_006714139 ENSP00000406229 Q14517 TRUE can 0 0 0 Last Universal Common Ancestor 0 Cell motility and interactions,Cellular processes,Development chr4 187509749 187630981 |CDHF7|CDHR8|ME5|hFat1| XP_005262891 0 FALSE 2 11 504 0.0550
2196 FAT2 FAT atypical cadherin 2 5q33.1 5041 3596 604269 NP_001438;XP_006714824 NM_001447;XM_006714761 ENSP00000261800 Q9NYQ8 TRUE can 0 0 0 Eukaryotes 0 Cell motility and interactions chr5 150885129 150948492 |CDHF8|CDHR9|HFAT2|MEGF1| NP_001438 0 FALSE 4
2205 FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide 1q23 917 3609 147140 NP_001992 NM_002001 ENSP00000357097 P12319 TRUE can 0 0 0 Mammals 0 Cell response to stimuli,Cellular metabolism,Cellular processes,Immune system response,Regulation of intracellular processes and metabolism,Signal transduction chr1 159272155 159277719 |FCE1A|FcERI| NP_001992 0 FALSE 1 6 74 0.2000
2213 FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32) 1q23 6849 3618 604590 NP_001002273;NP_001002274;NP_001002275;NP_001177757;NP_003992 NM_001002273;NM_001002274;NM_001002275;NM_001190828;NM_004001 ENSP00000351497 P31994 TRUE cgc 1 0 2 Mammals 0 Signal transduction chr1 161633032 161647340 |CD32B| NP_003992 2 FALSE 1 19 7514 0.3040 1
2243 FGA fibrinogen alpha chain 4q28 619 3661 134820 NP_000499;NP_068657 NM_000508;NM_021871 ENSP00000306361 P02671 TRUE can 0 0 0 Eukaryotes 6 Cellular metabolism,Cellular processes,Development,Multicellular activities,Signal transduction chr4 155505279 155511839 |Fib2| NP_000499 0 FALSE 1 23 3861 0.1580 18
2250 FGF5 fibroblast growth factor 5 4q21 1307 3683 165190 NP_004455;NP_149134 NM_004464;NM_033143 ENSP00000311697 P12034 TRUE can 0 0 0 Metazoans 3 Development,Signal transduction chr4 81187979 81207823 |HBGF-5|Smag-82|TCMGLY| NP_004455 0 FALSE 1 6 106 0.0000 86
2260 FGFR1 fibroblast growth factor receptor 1 8p11.23-p11.22 634 3688 136350 NP_001167534;NP_001167535;NP_001167536;NP_001167537;NP_001167538;NP_056934;NP_075593;NP_075594;NP_075598;XP_006716366;XP_006716367;XP_006716368;XP_006716369;XP_006716370;XP_006716371;XP_006716372;XP_006716373;XP_006716374;XP_006716375;XP_006716376;XP_006716377 NM_001174063;NM_001174064;NM_001174065;NM_001174066;NM_001174067;NM_015850;NM_023105;NM_023106;NM_023107;NM_023108;NM_023109;NM_023110;NM_023111;NM_032191;XM_006716303;XM_006716304;XM_006716305;XM_006716306;XM_006716307;XM_006716308;XM_006716309;XM_006716310;XM_006716311;XM_006716312;XM_006716313;XM_006716314 ENSP00000393312 P11362 TRUE cgc 1 0 0 Eukaryotes 7 Cell cycle,Cellular metabolism,Cellular processes,Development,Signal transduction chr8 38271149 38315054 |BFGFR|CD331|CEK|FGFBR|FGFR-1|FLT-2|FLT2|HBGFR|HH2|HRTFDS|KAL2|N-SAM|OGD|bFGF-R-1| NP_001167538 0 FALSE 2 64 100763 0.0710 38
2261 FGFR3 fibroblast growth factor receptor 3 4p16.3 624 3690 134934 NP_000133;NP_001156685;NP_075254;XP_006713931;XP_006713932;XP_006713933;XP_006713934;XP_006713935;XP_006713936 NM_000142;NM_001163213;NM_022965;XM_006713868;XM_006713869;XM_006713870;XM_006713871;XM_006713872;XM_006713873 ENSP00000339824 P22607 TRUE cgc 1 0 0 Eukaryotes 3 Cell cycle,Cell response to stimuli,Cellular metabolism,Cellular processes,Development,Signal transduction chr4 1795662 1808986 |ACH|CD333|CEK2|HSFGFR3EX|JTK4| NP_001156685 0 FALSE 4 47 50232 0.0350 28
2262 GPC5 glypican 5 13q32 3902 4453 602446 NP_004457 NM_004466 ENSP00000366267 P78333 TRUE can 0 0 0 Metazoans 0 -1 chr13 92051301 92797241 |NA| NP_004457 0 FALSE 1 1 0 0.0000 4
2263 FGFR2 fibroblast growth factor receptor 2 10q26 1492 3689 176943 NP_000132;NP_001138385;NP_001138386;NP_001138387;NP_001138388;NP_001138389;NP_001138390;NP_001138391;NP_075259;NP_075418;XP_006717771;XP_006717772;XP_006717773;XP_006717774;XP_006717775;XP_006717776 NM_000141;NM_001144913;NM_001144914;NM_001144915;NM_001144916;NM_001144917;NM_001144918;NM_001144919;NM_022970;NM_022971;NM_022972;NM_022973;NM_022974;NM_022975;NM_022976;NM_023028;NM_023029;NM_023030;NR_073009;XM_006717708;XM_006717709;XM_006717710;XM_006717711;XM_006717712;XM_006717713 ENSP00000410294 P21802 TRUE cgc 1 0 0 Eukaryotes 2 Cell cycle,Cellular metabolism,Cellular processes,Signal transduction chr10 123239374 123353331 |BBDS|BEK|BFR-1|CD332|CEK3|ECT1|JWS|K-SAM|KGFR|TK14|TK25| NP_075259 0 FALSE 5 48 74942 0.0470 32
2264 FGFR4 fibroblast growth factor receptor 4 5q35.2 625 3691 134935 NP_002002;NP_075252;NP_998812;XP_005265894;XP_005265895 NM_002011;NM_022963;NM_213647;XM_005265837;XM_005265838;XR_427801 ENSP00000292408 P22455 TRUE can 0 0 0 Last Universal Common Ancestor 0 Cellular metabolism,Cellular processes,Signal transduction chr5 176514594 176524674 |CD334|JTK2|TKF| XP_005265894 0 FALSE 2 37 13328 0.0060 30
2271 FH fumarate hydratase 1q42.1 652 3700 136850 NP_000134 NM_000143 ENSP00000355518;ENSP00000356399;ENSP00000454071 P07954 TRUE cgc 0 1 0 Last Universal Common Ancestor 0 Cell cycle,Cellular metabolism,Multicellular activities,Regulation of intracellular processes and metabolism chr1 241661131 241683022 |HLRCC|LRCC|MCUL1| NP_000134 0 FALSE 2 39 4996 0.1320
2272 FHIT fragile histidine triad 3p14.2 3096 3701 601153 NP_001159715;NP_002003;XP_005265008;XP_005265009;XP_005265010;XP_006713090 NM_001166243;NM_002012;XM_005264951;XM_005264952;XM_005264953;XM_006713027 ENSP00000342087;ENSP00000458888 P49789 TRUE cgc 1 0 0 Last Universal Common Ancestor 0 Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism chr3 59737955 60522713 |AP3Aase|FRA3B| XP_005265008 0 FALSE 1 14 4122 0.1320 2
2304 FOXE1 forkhead box E1 (thyroid transcription factor 2) 9q22 4014 3806 602617 NP_004464 NM_004473 ENSP00000364265 O00358 TRUE can 0 0 0 Eukaryotes 1 Cell motility and interactions,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Regulation of transcription chr9 100616197 100617315 |FKHL15|FOXE2|HFKH4|HFKL5|TITF2|TTF-2| NP_004464 0 FALSE 1 1 0 0.0000
2308 FOXO1 forkhead box O1 13q14.1 645 3819 136533 NP_002006 NM_002015 ENSP00000368880 Q12778 TRUE cgc 1 0 0 Eukaryotes 12 Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction chr13 41133663 41240349 |FKH1|FKHR|FOXO1A| NP_002006 0 FALSE 2 48 18362 0.1790 2
2309 FOXO3 forkhead box O3 6q21 4061 3821 602681 NP_001446;NP_963853;XP_005266924;XP_005266925 NM_001455;NM_201559;XM_005266867;XM_005266868 ENSP00000339527 O43524 TRUE cgc 1 0 1 Eukaryotes 10 Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Regulation of transcription chr6 108882412 108986055 |AF6q21|FKHRL1|FKHRL1P2|FOXO2|FOXO3A| NP_001446 1 FALSE 1 52 11344 0.2000 6
2313 FLI1 Fli-1 proto-oncogene, ETS transcription factor 11q24.1-q24.3 1901 3749 193067 NP_001161153;NP_001257939;NP_001257941;NP_002008 NM_001167681;NM_001271010;NM_001271012;NM_002017 ENSP00000399985 Q01543 TRUE cgc 1 0 0 Metazoans 5 Cellular metabolism,DNA/RNA metabolism and transcription,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Regulation of transcription chr11 128628010 128680880 |SIC-1| NP_002008 0 FALSE 1 21 1523 0.1240 2
2321 FLT1 fms-related tyrosine kinase 1 13q12 1297 3763 165070 NP_001153392;NP_001153502;NP_001153503;NP_002010 NM_001159920;NM_001160030;NM_001160031;NM_002019 ENSP00000282397 P17948 TRUE can 0 0 0 Eukaryotes 3 Cell cycle,Cell motility and interactions,Cellular metabolism,Cellular processes,Development,Regulation of intracellular processes and metabolism,Signal transduction chr13 28877307 29068980 |FLT|FLT-1|VEGFR-1|VEGFR1| NP_002010 0 FALSE 1 33 13974 0.2250 2
2322 FLT3 fms-related tyrosine kinase 3 13q12 635 3765 136351 NP_004110 NM_004119 ENSP00000241453 P36888 TRUE cgc 1 0 0 Eukaryotes 2 Cell cycle,Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism,Signal transduction chr13 28578192 28674647 |CD135|FLK-2|FLK2| NP_004110 0 FALSE 2 20 20202 0.2000
2324 FLT4 fms-related tyrosine kinase 4 5q35.3 636 3767 136352 NP_002011;NP_891555 NM_002020;NM_182925 ENSP00000261937 P35916 TRUE can 0 0 0 Eukaryotes 0 Cell cycle,Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism,Signal transduction chr5 180030195 180076545 |FLT41|LMPH1A|VEGFR3| NP_891555 0 FALSE 1 17 9079 0.2130 2
2334 AFF2 AF4/FMR2 family, member 2 Xq28 2397 3776 300806 NP_001162593;NP_001162594;NP_001162595;NP_001162596;NP_001164099;NP_002016 NM_001169122;NM_001169123;NM_001169124;NM_001169125;NM_001170628;NM_002025 ENSP00000359489;ENSP00000472279 P51816 TRUE can 0 0 0 Metazoans 0 Development chrX 147582618 148072859 |FMR2P|OX19| NP_002016 0 FALSE 1 4 2 0.8330
2475 MTOR mechanistic target of rapamycin (serine/threonine kinase) 1p36.2 3134 3942 601231 NP_004949;XP_005263495;XP_005263496 NM_004958;XM_005263438;XM_005263439;XR_244786 ENSP00000354558 P42345 TRUE can 0 0 0 Eukaryotes 7 Cell cycle,Cell response to stimuli,Cellular metabolism,Signal transduction chr1 11168237 11319466 |FRAP|FRAP1|FRAP2|RAFT1|RAPT1| NP_004949 0 FALSE 3 112 83557 0.0870 26
2515 ADAM2 ADAM metallopeptidase domain 2 8p11.2 3322 198 601533 NP_001265042;NP_001265043;NP_001455;XP_005273525;XP_006725182 NM_001278113;NM_001278114;NM_001464;XM_005273468;XM_006725119 ENSP00000265708 Q99965 TRUE can 0 0 0 Eukaryotes 1 Cellular metabolism,Cellular processes,Development chr8 39603990 39695704 |CRYN1|CRYN2|CT15|FTNB|PH-30b|PH30|PH30-beta| NP_001455 0 FALSE 1 4 133 0.0000 3
2521 FUS FUS RNA binding protein 16p11.2 660 4010 137070 NP_001164105;NP_001164408;NP_004951;XP_005255290 NM_001010850;NM_001170634;NM_001170937;NM_004960;NR_028388;XM_005255233 ENSP00000254108 P35637 TRUE cgc 1 0 0 Eukaryotes 1 DNA/RNA metabolism and transcription,Regulation of transcription chr16 31193832 31202432 |ETM4|HNRNPP2|POMP75|TLS| NP_004951 0 FALSE 1 298 388794 0.0760 8
2531 KDSR 3-ketodihydrosphingosine reductase 18q21.3 640 4021 136440 NP_002026;XP_005266734;XP_006722496 NM_002035;XM_005266677;XM_006722433 ENSP00000385083 Q06136 TRUE cgc 1 0 0 Last Universal Common Ancestor 6 -1 chr18 60999018 61034351 |DHSR|FVT1|SDR35C1| NP_002026 0 FALSE 1 2 0 1.0000
2534 FYN FYN proto-oncogene, Src family tyrosine kinase 6q21 655 4037 137025 NP_002028;NP_694592;NP_694593;XP_005266944;XP_005266945;XP_005266946;XP_005266947;XP_005266949;XP_006715492 NM_001242779;NM_002037;NM_153047;NM_153048;XM_005266887;XM_005266888;XM_005266889;XM_005266890;XM_005266892;XM_006715429 ENSP00000346671 P06241 TRUE can 0 0 1 Last Universal Common Ancestor 2 Cell response to stimuli,Cellular metabolism,Cellular processes,Immune system response,Multicellular activities,Signal transduction chr6 111982945 112041254 |p59-FYN| NP_002028 1 FALSE 1 344 513963 0.0350 88
2538 G6PC glucose-6-phosphatase, catalytic subunit 17q21 - 4056 613742 NP_000142;NP_001257326 NM_000151;NM_001270397 ENSP00000253801 P35575 TRUE can 0 0 0 Metazoans 0 Cell response to stimuli,Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism chr17 41052894 41063440 |G6PC1|G6PT|GSD1|GSD1a| NP_000142 0 FALSE 1 4 85 0.0000
2554 GABRA1 gamma-aminobutyric acid (GABA) A receptor, alpha 1 5q34 662 4075 137160 NP_000797;NP_001121115;NP_001121116;NP_001121117;NP_001121120 NM_000806;NM_001127643;NM_001127644;NM_001127645;NM_001127646;NM_001127647;NM_001127648 ENSP00000023897 P14867 TRUE can 0 0 2 Metazoans 1 Cellular processes,Signal transduction chr5 161277817 161324425 |ECA4|EIEE19|EJM5| NP_000797 2 FALSE 2 5 255 0.0000 7
2559 GABRA6 gamma-aminobutyric acid (GABA) A receptor, alpha 6 5q34 8841 4080 137143 NP_000802 NM_000811 ENSP00000274545 Q16445 TRUE can 0 0 1 Metazoans 0 Cellular processes,Signal transduction chr5 161112996 161128776 |NA| NP_000802 1 FALSE 2 1 0 0.0000 1
2561 GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2 5q34 2578 4082 600232 NP_000804;NP_068711 NM_000813;NM_021911 ENSP00000274547 P47870 TRUE can 0 0 2 Last Universal Common Ancestor 0 Cellular processes,Multicellular activities,Signal transduction chr5 160721091 160973649 |NA| NP_068711 2 FALSE 2 5 230 0.0000 6
2565 GABRG1 gamma-aminobutyric acid (GABA) A receptor, gamma 1 4p12 15923 4086 137166 NP_775807 NM_173536 ENSP00000295452 Q8N1C3 TRUE can 0 0 0 Metazoans 0 Cellular processes,Multicellular activities,Signal transduction chr4 46043008 46125930 |NA| NP_775807 0 FALSE 1 1 0 0.0000 2
2623 GATA1 GATA binding protein 1 (globin transcription factor 1) Xp11.23 2372 4170 305371 NP_002040 NM_002049 ENSP00000365858;ENSP00000469059 P15976 TRUE cgc 1 0 0 Eukaryotes 1 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chrX 48649517 48652568 |ERYF1|GATA-1|GF-1|NFE1|XLANP|XLTDA|XLTT| NP_002040 0 FALSE 1 65 22493 0.0810 4
2624 GATA2 GATA binding protein 2 3q21.3 673 4171 137295 NP_001139133;NP_001139134;NP_116027 NM_001145661;NM_001145662;NM_032638 ENSP00000345681 P23769 TRUE cgc 1 0 0 Eukaryotes 1 Cell cycle,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription chr3 128199865 128205874 |DCML|IMD21|MONOMAC|NFE1B| NP_001139133 0 FALSE 1 37 14878 0.1730 4
2625 GATA3 GATA binding protein 3 10p15 572 4172 131320 NP_001002295;NP_002042;XP_005252499;XP_005252500 NM_001002295;NM_002051;XM_005252442;XM_005252443 ENSP00000368632 P23771 TRUE cgc 0 1 0 Eukaryotes 3 Cell response to stimuli,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Regulation of transcription chr10 8097619 8115983 |HDR|HDRS| NP_001002295 0 FALSE 2 23 1419 0.1030 1
2719 GPC3 glypican 3 Xq26.1 2074 4451 300037 NP_001158089;NP_001158090;NP_001158091;NP_004475 NM_001164617;NM_001164618;NM_001164619;NM_004484 ENSP00000377836 P51654 TRUE cgc 0 1 0 Metazoans 0 -1 chrX 132670155 133119476 |DGSX|GTR2-2|MXR7|OCI-5|SDYS|SGB|SGBS|SGBS1| NP_001158089 0 FALSE 1 5 275 0.0000 2
2737 GLI3 GLI family zinc finger 3 7p13 1313 4319 165240 NP_000159;XP_005249760;XP_005249761 NM_000168;XM_005249703;XM_005249704 ENSP00000379258 P10071 TRUE can 0 0 0 Eukaryotes 0 Cell cycle,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction chr7 42003931 42262852 |GCPS|GLI3-190|GLI3FL|PAP-A|PAPA1|PAPB|PPDIV| NP_000159 0 FALSE 2 19 7816 0.1640 10
2765 GML glycosylphosphatidylinositol anchored molecule like 8q24.3 3844 4375 602370 NP_002057 NM_002066 ENSP00000220940 Q99445 TRUE can 0 0 0 Mammals 0 Cell cycle,Regulation of intracellular processes and metabolism,Signal transduction chr8 143921854 143928103 |LY6DL| NP_002057 0 FALSE 1
2767 GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) 19p13.3 759 4379 139313 NP_002058 NM_002067 ENSP00000078429 P29992 TRUE cgc 1 0 3 Eukaryotes 0 Cellular metabolism,Cellular processes,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Signal transduction chr19 3094650 3121174 |FBH|FBH2|FHH2|GNA-11|HHC2|HYPOC2| NP_002058 3 FALSE 1 24 10203 0.0580 17
2769 GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class) 19p13.3 760 4383 139314 NP_002059 NM_002068 ENSP00000262958 P30679 TRUE can 0 0 0 Eukaryotes 0 Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism,Signal transduction chr19 3136449 3163014 |GNA16| NP_002059 0 FALSE 1 24 19786 0.0620 14
2771 GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 3p21.31 764 4385 139360 NP_001159897;NP_001269546;NP_001269547;NP_001269548;NP_001269549;NP_002061 NM_001166425;NM_001282617;NM_001282618;NM_001282619;NM_001282620;NM_002070 ENSP00000312999;ENSP00000350005;ENSP00000460235 P04899 TRUE can 0 0 2 Eukaryotes 4 Cell response to stimuli,Regulation of intracellular processes and metabolism,Signal transduction chr3 50273768 50295119 |GNAI2B|H_LUCA15.1|H_LUCA16.1| NP_002061 2 FALSE 1 94 149916 0.0450 12
2776 GNAQ guanine nucleotide binding protein (G protein), q polypeptide 9q21 2998 4390 600998 NP_002063 NM_002072 ENSP00000078429 P50148 TRUE cgc 1 0 3 Eukaryotes 4 Cell cycle,Cellular metabolism,Cellular processes,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Signal transduction chr9 80336242 80646151 |G-ALPHA-q|GAQ| NP_002063 3 FALSE 1 64 64402 0.0190 18
2778 GNAS GNAS complex locus 20q13.3 761 4392 139320 NP_000507;NP_001070956;NP_001070957;NP_001070958;NP_057676;NP_536350;NP_536351;XP_005260458;XP_005260459;XP_006723844;XP_006723845 NM_000516;NM_001077488;NM_001077489;NM_001077490;NM_016592;NM_080425;NM_080426;NR_003259;XM_005260401;XM_005260402;XM_006723781;XM_006723782 ENSP00000360141 P84996 TRUE cgc 1 0 0 Metazoans 1 Cell response to stimuli,Cellular processes,Regulation of intracellular processes and metabolism,Signal transduction chr20 57415162 57415896 |AHO|GNAS1|GPSA|GSA|NESP|PHP1A|PHP1B|PHP1C|POH| NP_057676 0 FALSE 7 51 62931 0.0420 12
2779 GNAT1 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1 3p21 - 4393 139330 NP_000163;NP_653082 NM_000172;NM_144499 ENSP00000232461 P11488 TRUE can 0 0 2 Eukaryotes 0 Cell response to stimuli,Signal transduction chr3 50229159 50232385 |CSNBAD3|GBT1|GNATR| NP_000163 2 FALSE 1 5 127 0.0000 6
2847 MCHR1 melanin-concentrating hormone receptor 1 22q13.2 11874 4479 601751 NP_005288;XP_005261638 NM_005297;XM_005261581 ENSP00000249016 Q99705 TRUE can 0 0 0 Metazoans 0 Regulation of intracellular processes and metabolism,Signal transduction chr22 41075450 41077929 |GPR24|MCH-1R|MCH1R|SLC-1|SLC1| NP_005288 0 FALSE 1 2 66 0.0000 5
2854 GPR32 G protein-coupled receptor 32 19q13.33 4430 4487 603195 NP_001497 NM_001506 ENSP00000270590 O75388 TRUE can 0 0 1 Mammals 0 Signal transduction chr19 51273858 51274925 |RVDR1| NP_001497 1 FALSE 1
2874 GPS2 G protein pathway suppressor 2 17p13 11878 4550 601935 NP_004480 NM_004489 ENSP00000370104;ENSP00000382390;ENSP00000468772 Q13227 TRUE can 0 0 1 Metazoans 0 Regulation of intracellular processes and metabolism,Signal transduction chr17 7216078 7218371 |AMF-1| NP_004480 1 FALSE 2 34 10705 0.1320 10
2880 GPX5 glutathione peroxidase 5 6p22.1 11941 4557 603435 NP_001500;NP_003987 NM_001509;NM_003996 ENSP00000392398;ENSP00000450365 O75715 TRUE can 0 0 0 Last Universal Common Ancestor 0 -1 chr6 28493791 28501941 |HEL-S-75p| NP_001500 0 FALSE 1
2885 GRB2 growth factor receptor-bound protein 2 17q24-q25 150 4566 108355 NP_002077;NP_987102 NM_002086;NM_203506 ENSP00000339007 P62993 TRUE can 0 0 0 Eukaryotes 11 Signal transduction chr17 73316452 73389709 |ASH|EGFRBP-GRB2|Grb3-3|MST084|MSTP084|NCKAP2| NP_002077 0 FALSE 1 722 2378436 0.0220 176
2892 GRIA3 glutamate receptor, ionotropic, AMPA 3 Xq25 2378 4573 305915 NP_000819;NP_001243672;NP_015564 NM_000828;NM_001256743;NM_007325;NM_181894 ENSP00000264357 P42263 TRUE can 0 0 0 Eukaryotes 0 Cellular processes,Signal transduction chrX 122318388 122616892 |GLUR-C|GLUR-K3|GLURC|GluA3|MRX94| NP_000819 0 FALSE 1 12 997 0.1520 1
2899 GRIK3 glutamate receptor, ionotropic, kainate 3 1p34.3 691 4581 138243 NP_000822 NM_000831 ENSP00000362183 Q13003 TRUE can 0 0 1 Eukaryotes 0 Cellular processes,Regulation of intracellular processes and metabolism,Signal transduction chr1 37267455 37499709 |EAA5|GLR7|GluK3|GluR7a| NP_000822 1 FALSE 1 5 255 0.1000 1
2903 GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A 16p13.2 698 4585 138253 NP_000824;NP_001127879;NP_001127880;XP_005255324;XP_005255325 NM_000833;NM_001134407;NM_001134408;XM_005255267;XM_005255268 ENSP00000332549 Q12879 TRUE can 0 0 0 Metazoans 1 Cellular processes,Development,Multicellular activities,Signal transduction chr16 9857009 10274424 |EPND|FESD|GluN2A|LKS|NMDAR2A|NR2A| XP_005255324 0 FALSE 1 30 6754 0.1520 5
2911 GRM1 glutamate receptor, metabotropic 1 6q24 5129 4593 604473 NP_000829;NP_001264993;NP_001264994;NP_001264995;NP_001264996;XP_006715530;XP_006715531 NM_000838;NM_001114329;NM_001278064;NM_001278065;NM_001278066;NM_001278067;XM_006715467;XM_006715468 ENSP00000282753 Q13255 TRUE can 0 0 0 Eukaryotes 3 Multicellular activities,Signal transduction chr6 146350654 146755929 |GPRC1A|MGLU1|MGLUR1|PPP1R85|SCAR13| NP_001264993 0 FALSE 2 16 3500 0.0920 3
2913 GRM3 glutamate receptor, metabotropic 3 7q21.1-q21.2 3070 4595 601115 NP_000831;XP_005250347;XP_006716000 NM_000840;XM_005250290;XM_006715937 ENSP00000355316 Q14832 TRUE can 0 0 1 Eukaryotes 1 Multicellular activities,Regulation of intracellular processes and metabolism,Signal transduction chr7 86394462 86493668 |GPRC1C|MGLUR3|mGlu3| NP_000831 1 FALSE 2 5 394 0.1000 2
2918 GRM8 glutamate receptor, metabotropic 8 7q31.3-q32.1 3071 4600 601116 NP_000836;NP_001120795;XP_006716001 NM_000845;NM_001127323;NR_028041;XM_006715938 ENSP00000344173 O00222 TRUE can 0 0 2 Eukaryotes 1 Cell response to stimuli,Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction chr7 126079176 126883258 |GLUR8|GPRC1H|MGLUR8|mGlu8| NP_000836 2 FALSE 3 4 172 0.1670 2
2956 MSH6 mutS homolog 6 2p16 - 7329 600678 NP_000170;NP_001268421;NP_001268422;NP_001268423;XP_005264328 NM_000179;NM_001281492;NM_001281493;NM_001281494;XM_005264271 ENSP00000234420 P52701 TRUE cgc 0 1 0 Last Universal Common Ancestor 7 Cellular metabolism,DNA/RNA metabolism and transcription chr2 48010373 48033996 |GTBP|GTMBP|HNPCC5|HSAP|p160| NP_000170 0 FALSE 1 58 6513 0.1920 25
2969 GTF2I general transcription factor IIi 7q11.23 3399 4659 601679 NP_001157108;NP_001267729;NP_001509;NP_127492;NP_127493;NP_127494;XP_005250348;XP_005250353;XP_006716002;XP_006716003;XP_006716004;XP_006716005;XP_006716006;XP_006716007;XP_006716008;XP_006716009 NM_001163636;NM_001280800;NM_001518;NM_032999;NM_033000;NM_033001;XM_005250291;XM_005250296;XM_006715939;XM_006715940;XM_006715941;XM_006715942;XM_006715943;XM_006715944;XM_006715945;XM_006715946 ENSP00000322542;ENSP00000460070 P78347 TRUE can 0 0 2 Vertebrates 2 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction chr7 74103460 74173165 |BAP135|BTKAP1|DIWS|GTFII-I|IB291|TFII-I|WBSCR6| XP_005250348 2 FALSE 1 90 44866 0.0780 6
2977 GUCY1A2 guanylate cyclase 1, soluble, alpha 2 11q21-q22 3146 4684 601244 NP_000846;NP_001243353 NM_000855;NM_001256424 ENSP00000431245 P33402 TRUE can 0 0 0 Last Universal Common Ancestor 1 Cellular metabolism,DNA/RNA metabolism and transcription,Signal transduction chr11 106558278 106888781 |GC-SA2|GUC1A2| NP_001243353 0 FALSE 1 10 863 0.2440 1
3006 HIST1H1C histone cluster 1, H1c 6p21.3 7514 4716 142710 NP_005310 NM_005319 ENSP00000339566 P16403 TRUE can 0 0 3 Metazoans 2 DNA/RNA metabolism and transcription chr6 26056018 26056656 |H1.2|H1C|H1F2|H1s-1| NP_005310 3 FALSE 1 75 30432 0.1400 3
3007 HIST1H1D histone cluster 1, H1d 6p21.3 6764 4717 142210 NP_005311 NM_005320 ENSP00000244534 P16402 TRUE can 0 0 3 Metazoans 3 DNA/RNA metabolism and transcription chr6 26234499 26235161 |H1.3|H1D|H1F3|H1s-2| NP_005311 3 FALSE 1 25 1855 0.1370 1
3008 HIST1H1E histone cluster 1, H1e 6p21.3 7513 4718 142220 NP_005312 NM_005321 ENSP00000307705 P10412 TRUE can 0 0 3 Metazoans 1 DNA/RNA metabolism and transcription chr6 26156619 26157275 |H1.4|H1E|H1F4|H1s-4|dJ221C16.5| NP_005312 3 FALSE 1 26 2019 0.1290
3009 HIST1H1B histone cluster 1, H1b 6p22.1 821 4719 142711 NP_005313 NM_005322 ENSP00000330074 P16401 TRUE can 0 0 3 Metazoans 3 DNA/RNA metabolism and transcription,Development chr6 27834630 27835307 |H1.5|H1B|H1F5|H1s-3| NP_005313 3 FALSE 1 43 7563 0.0910 2
3013 HIST1H2AD histone cluster 1, H2ad 6p21.3 - 4729 602792 NP_066409 NM_021065 ENSP00000341094 P20671 TRUE can 0 0 19 Eukaryotes 1 DNA/RNA metabolism and transcription chr6 26199082 26199471 |H2A.3|H2A/g|H2AFG| NP_066409 19 FALSE 1 20 119 0.4890
3017 HIST1H2BD histone cluster 1, H2bd 6p21.3 7535 4747 602799 NP_066407;NP_619790;XP_005249096 NM_021063;NM_138720;XM_005249039 ENSP00000289316 P58876 TRUE can 0 0 24 Eukaryotes 1 DNA/RNA metabolism and transcription chr6 26158326 26158775 |H2B.1B|H2B/b|H2BFB|HIRIP2|dJ221C16.6| XP_005249096 24 FALSE 1 27 2865 0.0400
3020 H3F3A H3 histone, family 3A 1q42.12 3082 4764 601128 NP_002098 NM_002107 ENSP00000254810 NA TRUE cgc 1 0 36 Last Universal Common Ancestor 1 -1 chr1 226252053 226259177 |H3.3A|H3F3| NP_002098 36 FALSE 2 101 37883 0.0670 27
3021 H3F3B H3 histone, family 3B (H3.3B) 17q25.1 3036 4765 601058 NP_005315 NM_005324 ENSP00000254810 NA TRUE can 0 0 -1 Last Universal Common Ancestor 10 DNA/RNA metabolism and transcription - 0 0 |H3.3B| - -1 FALSE 1
3080 CFHR2 complement factor H-related 2 1q31.3 2933 4890 600889 NP_005657;XP_005245170;XP_006711348 NM_005666;XM_005245113;XM_006711285 ENSP00000356385 P36980 TRUE can 0 0 1 Mammals 1 -1 chr1 196913011 196928207 |CFHL2|FHR2|HFL3| NP_005657 1 FALSE 1 1 0 0.0000
3092 HIP1 huntingtin interacting protein 1 7q11.23 3461 4913 601767 NP_001230127;NP_005329;XP_005250361;XP_005250362 NM_001243198;NM_005338;XM_005250304;XM_005250305 ENSP00000336747;ENSP00000460815 O00291 TRUE cgc 1 0 0 Eukaryotes 0 Cell cycle,Cellular processes,Regulation of intracellular processes and metabolism,Signal transduction chr7 75167496 75368238 |HIP-I| NP_005329 0 FALSE 1 25 2721 0.0830 2
3105 HLA-A major histocompatibility complex, class I, A 6p21.3 826 4931 142800 NP_001229687;NP_002107;XP_005275388;XP_006725813;XP_006725814;XP_006725920;XP_006725921;XP_006725922;XP_006726009;XP_006726109;XP_006726110;XP_006726198;XP_006726199;XP_006726200 NM_001242758;NM_002116;XM_005275331;XM_006725750;XM_006725751;XM_006725857;XM_006725858;XM_006725859;XM_006725946;XM_006726046;XM_006726047;XM_006726135;XM_006726136;XM_006726137;XR_430999 ENSP00000365394;ENSP00000383179;ENSP00000394553;ENSP00000400842;ENSP00000402134;ENSP00000416941 P30443 TRUE can 0 0 6 Vertebrates 8 Immune system response chr6 29910340 29913147 |HLAA| XP_005275388 6 FALSE 3 45 37997 0.1050 13
3106 HLA-B major histocompatibility complex, class I, B 6p21.3 828 4932 142830 NP_005505;XP_005249100;XP_005275157;XP_005275295;XP_005275433;XP_005275434;XP_005275592;XP_006725967;XP_006725968 NM_005514;XM_005249043;XM_005275100;XM_005275238;XM_005275376;XM_005275377;XM_005275535;XM_006725904;XM_006725905;XR_246962;XR_427830 ENSP00000365394;ENSP00000383179;ENSP00000394553;ENSP00000400842;ENSP00000402134;ENSP00000416941 P01889 TRUE can 0 0 6 Vertebrates 0 Immune system response chr6 31322263 31324852 |HLAB|SPDA1| XP_005275157 6 FALSE 2 32 22441 0.0380 10
3110 MNX1 motor neuron and pancreas homeobox 1 7q36 874 4979 142994 NP_001158727;NP_005506;XP_006716020 NM_001165255;NM_005515;XM_006715957 ENSP00000252971 P50219 TRUE cgc 1 0 0 Vertebrates 2 Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription chr7 156798217 156803044 |HB9|HLXB9|HOXHB9|SCRA1| NP_005506 0 FALSE 1 1 0 0.0000
3131 HLF hepatic leukemia factor 17q22 797 4977 142385 NP_002117;XP_005257326 NM_002126;XM_005257269 ENSP00000263734 Q16534 TRUE cgc 1 0 0 Metazoans 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr17 53342846 53398237 |NA| XP_005257326 0 FALSE 1 5 57 0.2000 1
3132 HLA-DRB9 major histocompatibility complex, class II, DR beta 9 (pseudogene) 6p21.3 - - - - - - NA TRUE can 0 0 -1 - 0 -1 - 0 0 |D6S206|D6S206E|HLA-DR1BL|HLA-DRB1L| - -1 FALSE 1
3146 HMGB1 high mobility group box 1 13q12 1228 4983 163905 NP_002119;XP_005266420;XP_005266422;XP_005266425 NM_002128;XM_005266363;XM_005266365;XM_005266368 ENSP00000343040 P09429 TRUE can 0 0 24 Eukaryotes 3 Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction chr13 31035497 31037817 |HMG1|HMG3|SBP-1| NP_002119 24 FALSE 1 94 110896 0.0500 7
3159 HMGA1 high mobility group AT-hook 1 6p21 2829 5010 600701 NP_002122;NP_665906;NP_665908;NP_665909;NP_665910;NP_665912;XP_005249118 NM_002131;NM_145899;NM_145901;NM_145902;NM_145903;NM_145904;NM_145905;XM_005249061 ENSP00000308227 P17096 TRUE cgc 1 0 5 Mammals 10 Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Multicellular activities,Other,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction chr12 110867767 110868087 |HMG-R|HMGA1A|HMGIY| NP_665906 5 FALSE 1 78 22708 0.1330 12
3169 FOXA1 forkhead box A1 14q12-q13 3801 5021 602294 NP_004487 NM_004496 ENSP00000250448 P55317 TRUE cgc 1 0 0 Metazoans 3 Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription chr14 38060573 38064177 |HNF3A|TCF3A| NP_004487 0 FALSE 4 9 2233 0.1390
3177 SLC29A2 solute carrier family 29 (equilibrative nucleoside transporter), member 2 11q13 3662 11004 602110 NP_001523;XP_006718586;XP_006718587;XP_006718588;XP_006718589;XP_006718590;XP_006718591 NM_001532;XM_006718523;XM_006718524;XM_006718525;XM_006718526;XM_006718527;XM_006718528;XR_428912 ENSP00000350024 Q14542 TRUE can 0 0 0 Eukaryotes 0 DNA/RNA metabolism and transcription chr11 66130910 66138798 |DER12|ENT2|HNP36| NP_001523 0 FALSE 1 2 918 0.0000
3181 HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 7p15 2526 5033 600124 NP_002128;NP_112533;XP_005249786;XP_006715777 NM_002137;NM_031243;XM_005249729;XM_006715714;XR_242076;XR_242077;XR_428077;XR_428078 ENSP00000346694 P22626 TRUE cgc 1 0 0 Eukaryotes 4 Cellular processes,DNA/RNA metabolism and transcription,Regulation of transcription chr7 26232139 26237486 |HNRNPA2|HNRNPB1|HNRPA2|HNRPA2B1|HNRPB1|IBMPFD2|RNPA2| NP_112533 0 FALSE 2 154 54414 0.1440 9
3190 HNRNPK heterogeneous nuclear ribonucleoprotein K 9q21.32-q21.33 2834 5044 600712 NP_002131;NP_112552;NP_112553;XP_005252017;XP_005252018;XP_005252020;XP_005252021;XP_005252022;XP_005252023 NM_002140;NM_031262;NM_031263;XM_005251960;XM_005251961;XM_005251963;XM_005251964;XM_005251965;XM_005251966 ENSP00000365439 P61978 TRUE can 0 0 3 - 3 DNA/RNA metabolism and transcription,Regulation of transcription,Signal transduction chr9 86585079 86593167 |HNRPK|TUNP| NP_002131 3 FALSE 1 227 190125 0.1160 12
3195 TLX1 T-cell leukemia homeobox 1 10q24 1728 5056 186770 NP_001182446;NP_005512 NM_001195517;NM_005521 ENSP00000359215 P31314 TRUE cgc 1 0 0 Vertebrates 2 Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription chr10 102891299 102896667 |HOX11|TCL3| NP_005512 0 FALSE 1 14 1101 0.1210
3204 HOXA7 homeobox A7 7p15.2 838 5108 142950 NP_008827 NM_006896 ENSP00000242159 P31268 TRUE can 0 0 0 Metazoans 2 Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription chr7 27194531 27196164 |ANTP|HOX1.1|HOX1A| NP_008827 0 FALSE 1 5 505 0.1000
3205 HOXA9 homeobox A9 7p15.2 844 5109 142956 NP_689952 NM_152739 ENSP00000343619 P31269 TRUE cgc 1 0 0 Metazoans 12 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr7 27203225 27205076 |ABD-B|HOX1.7|HOX1G| NP_689952 0 FALSE 1 17 2454 0.1470 2
3207 HOXA11 homeobox A11 7p15.2 846 5101 142958 NP_005514 NM_005523 ENSP00000006015 P31270 TRUE cgc 1 0 0 Vertebrates 3 Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction chr7 27222418 27224763 |HOX1I| NP_005514 0 FALSE 1 7 160 0.3810
3209 HOXA13 homeobox A13 7p15.2 - 5102 142959 NP_000513 NM_000522 ENSP00000222753 P31271 TRUE cgc 1 0 0 Metazoans 3 Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription chr7 27237820 27239696 |HOX1J| NP_000513 0 FALSE 1 6 14719 0.2000
3227 HOXC11 homeobox C11 12q13.3 9275 5123 605559 NP_055027 NM_014212 ENSP00000446680 O43248 TRUE cgc 1 0 0 Opisthokonts 0 Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction chr12 54367026 54369194 |HOX3H| NP_055027 0 FALSE 1 12 2385 0.1060
3229 HOXC13 homeobox C13 12q13.3 862 5125 142976 NP_059106 NM_017410 ENSP00000243056 P31276 TRUE cgc 1 0 0 Vertebrates 1 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr12 54332691 54339037 |ECTD9|HOX3G| NP_059106 0 FALSE 1 7 265 0.0000
3237 HOXD11 homeobox D11 2q31.1 869 5134 142986 NP_067015 NM_021192;XR_241309 ENSP00000249504 P31277 TRUE cgc 1 0 0 Vertebrates 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr2 176972084 176973867 |HOX4F| NP_067015 0 FALSE 1 2 16 0.0000
3239 HOXD13 homeobox D13 2q31.1 872 5136 142989 NP_000514 NM_000523 ENSP00000376322 P35453 TRUE cgc 1 0 0 Vertebrates 2 Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription chr2 176957619 176959455 |BDE|BDSD|HOX4I|SPD| NP_000514 0 FALSE 1 6 172 0.4000
3242 HPD 4-hydroxyphenylpyruvate dioxygenase 12q24.31 2041 5147 609695 NP_001165464;NP_002141 NM_001171993;NM_002150 ENSP00000289004 P32754 TRUE can 0 0 0 Last Universal Common Ancestor 0 Cellular metabolism chr12 122277637 122295725 |4-HPPD|4HPPD|GLOD3|HPPDASE| NP_002141 0 FALSE 1 4 50 0.3330
3265 HRAS Harvey rat sarcoma viral oncogene homolog 11p15.5 1813 5173 190020 NP_001123914;NP_005334;NP_789765;XP_006718280;XP_006725199 NM_001130442;NM_005343;NM_176795;XM_006718217;XM_006725136;XR_242795;XR_430702 ENSP00000309845 P01112 TRUE cgc 1 0 2 Last Universal Common Ancestor 6 Cell motility and interactions,Development,Signal transduction chr11 532639 534322 |C-BAS/HAS|C-H-RAS|C-HA-RAS1|CTLO|H-RASIDX|HAMSV|RASH1|p21ras| NP_001123914 2 FALSE 6 117 88405 0.0390 22
3320 HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 14q32.33 777 5253 140571 NP_001017963;NP_005339 NM_001017963;NM_005348 ENSP00000335153 P07900 TRUE cgc 1 0 6 Last Universal Common Ancestor 3 Cell response to stimuli,Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism,Signal transduction chr14 102548052 102605741 |EL52|HSP86|HSP89A|HSP90A|HSP90N|HSPC1|HSPCAL4|HSPN|Hsp89|Hsp90|LAP-2| NP_001017963 6 FALSE 1 756 1866248 0.0280 88
3326 HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 6p12 6763 5258 140572 NP_001258898;NP_001258899;NP_001258900;NP_001258901;NP_031381;XP_005249132 NM_001271969;NM_001271970;NM_001271971;NM_001271972;NM_007355;NR_073528;XM_005249075 ENSP00000325875 P08238 TRUE cgc 1 0 9 Last Universal Common Ancestor 1 Cell response to stimuli,Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism chr6 44216367 44221332 |D6S182|HSP84|HSP90B|HSPC2|HSPCB| NP_001258898 9 FALSE 1 618 1202175 0.0300 29
3354 HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled 6q14-q15 1635 5291 182132 NP_000856 NM_000865 ENSP00000307766 P28566 TRUE can 0 0 0 Metazoans 0 Multicellular activities,Signal transduction chr6 87725053 87726147 |5-HT1E| NP_000856 0 FALSE 1 3 19 0.3330 2
3371 TNC tenascin C 9q33 1756 5318 187380 NP_002151;XP_005252029;XP_005252030;XP_005252031;XP_005252032;XP_006717159;XP_006717160;XP_006717161;XP_006717162;XP_006717163;XP_006717164 NM_002160;XM_005251972;XM_005251973;XM_005251974;XM_005251975;XM_006717096;XM_006717097;XM_006717098;XM_006717099;XM_006717100;XM_006717101 ENSP00000232975;ENSP00000265131 P24821 TRUE can 0 0 0 Last Universal Common Ancestor 1 Cell cycle,Development,Multicellular activities,Signal transduction chr9 117783439 117853297 |150-225|DFNA56|GMEM|HXB|JI| NP_002151 0 FALSE 1 6 1426 0.2670 9
3394 IRF8 interferon regulatory factor 8 16q24.1 3336 5358 601565 NP_002154;XP_006721250 NM_002163;XM_006721187 ENSP00000268638 Q02556 TRUE can 0 0 0 Metazoans 0 Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription chr16 85936622 85954885 |H-ICSBP|ICSBP|ICSBP1|IMD32A|IMD32B|IRF-8| NP_002154 0 FALSE 1 22 3262 0.1390
3399 ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein 1p36.13-p36.12 2608 5362 600277 NP_002158 NM_002167 ENSP00000363689 Q02535 TRUE can 0 0 0 Vertebrates 5 Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription chr1 23885454 23885917 |HEIR-1|bHLHb25| NP_002158 0 FALSE 1 39 7947 0.0490
3417 IDH1 isocitrate dehydrogenase 1 (NADP+), soluble 2q33.3 984 5382 147700 NP_001269315;NP_001269316;NP_005887 NM_001282386;NM_001282387;NM_005896 ENSP00000260985 O75874 TRUE cgc 1 0 1 Last Universal Common Ancestor 2 Cellular metabolism chr2 209101806 209116275 |HEL-216|HEL-S-26|IDCD|IDPC|PICD| NP_001269315 1 FALSE 6 33 13152 0.1420 1
3418 IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial 15q26.1 - 5383 147650 NP_001276839;NP_002159 NM_001289910;NM_002168 ENSP00000331897 P48735 TRUE cgc 1 0 0 Last Universal Common Ancestor 2 Cellular metabolism chr15 90627501 90645622 |D2HGA2|ICD-M|IDHM|IDPM|mNADP-IDH| NP_002159 0 FALSE 3 7 421 0.0950
3437 IFIT3 interferon-induced protein with tetratricopeptide repeats 3 10q24 5228 5411 604650 NP_001026853;NP_001276687;NP_001276688;NP_001540 NM_001031683;NM_001289758;NM_001289759;NM_001549 ENSP00000360876 O14879 TRUE can 0 0 0 Eukaryotes 6 -1 chr10 91098416 91099882 |CIG-49|GARG-49|IFI60|IFIT4|IRG2|ISG60|RIG-G| NP_001026853 0 FALSE 1 55 32841 0.1600
3481 IGF2 insulin-like growth factor 2 11p15.5 939 5466 147470 NP_000603;NP_001007140;NP_001121070 NM_000612;NM_001007139;NM_001127598 ENSP00000391826 P01344 TRUE can 0 0 0 Vertebrates 6 Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction chr11 2154220 2161526 |C11orf43|IGF-II|PP9974| NP_001121070 0 FALSE 1 24 22964 0.0470 13
3482 IGF2R insulin-like growth factor 2 receptor 6q26 928 5467 147280 NP_000867 NM_000876 ENSP00000349437 P11717 TRUE can 0 0 0 Opisthokonts 8 Cellular processes,Signal transduction chr6 160390279 160526113 |CD222|CIMPR|M6P-R|MPR1|MPRI| NP_000867 0 FALSE 2 26 17373 0.0770 2
3492 IGH immunoglobulin heavy locus 14q32.33 - - 146910 - - - NA TRUE cgc 1 0 -1 - 0 -1 - 0 0 |IGD1|IGH.1@|IGH@|IGHD@|IGHDY1|IGHJ|IGHJ@|IGHV|IGHV@| - -1 FALSE 1
3535 IGL immunoglobulin lambda locus 22q11.2 - - - - - - NA TRUE cgc 1 0 -1 - 0 -1 - 0 0 |IGL@| - -1 FALSE 1
3552 IL1A interleukin 1, alpha 2q14 - 5991 147760 NP_000566 NM_000575 ENSP00000263339 P01583 TRUE can 0 0 0 Mammals 2 Cell cycle,Cell response to stimuli,Development,Immune system response,Regulation of intracellular processes and metabolism chr2 113532647 113541347 |IL-1A|IL1|IL1-ALPHA|IL1F1| NP_000566 0 FALSE 1 10 1121 0.0440 11
3553 IL1B interleukin 1, beta 2q14 985 5992 147720 NP_000567;XP_006712559 NM_000576;XM_006712496 ENSP00000263341 P01584 TRUE can 0 0 0 Vertebrates 1 Cell cycle,Cell motility and interactions,Cell response to stimuli,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Immune system response,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction chr2 113587941 113593806 |IL-1|IL1-BETA|IL1F2| NP_000567 0 FALSE 1 18 18869 0.0780 11
3558 IL2 interleukin 2 4q26-q27 - 6001 147680 NP_000577 NM_000586 ENSP00000226730 P60568 TRUE cgc 1 0 0 Mammals 1 Cell cycle,Development,Immune system response,Regulation of intracellular processes and metabolism chr4 123372910 123377595 |IL-2|TCGF|lymphokine| NP_000577 0 FALSE 1 10 1187 0.1110 15
3561 IL2RG interleukin 2 receptor, gamma Xq13.1 2391 6010 308380 NP_000197 NM_000206 ENSP00000363318 P31785 TRUE can 0 0 0 Vertebrates 0 Signal transduction chrX 70327589 70331389 |CD132|CIDX|IL-2RG|IMD4|P64|SCIDX|SCIDX1| NP_000197 0 FALSE 1 26 3853 0.1450 15
3572 IL6ST interleukin 6 signal transducer 5q11.2 2824 6021 600694 NP_001177910;NP_002175;NP_786943;XP_005248553 NM_001190981;NM_002184;NM_175767;XM_005248496 ENSP00000338799 P40189 TRUE cgc 1 0 0 Vertebrates 4 Signal transduction chr5 55236913 55272106 |CD130|CDW130|IL-6RB| NP_002175 0 FALSE 1 37 44374 0.1400 20
3575 IL7R interleukin 7 receptor 5p13 893 6024 146661 NP_002176;XP_005248356;XP_005248357 NM_002185;XM_005248299;XM_005248300 ENSP00000306157 P16871 TRUE cgc 1 0 0 Vertebrates 1 DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction chr5 35857080 35876585 |CD127|CDW127|IL-7R-alpha|IL7RA|ILRA| NP_002176 0 FALSE 1 103 23628 0.0980 3
3597 IL13RA1 interleukin 13 receptor, alpha 1 Xq24 2125 5974 300119 NP_001551;XP_005262468 NM_001560;XM_005262411 ENSP00000360730 P78552 TRUE can 0 0 0 Vertebrates 0 Signal transduction chrX 117861602 117925814 |CD213A1|IL-13Ra|NR4| NP_001551 0 FALSE 1 9 4189 0.1670
3624 INHBA inhibin, beta A 7p15-p13 - 6066 147290 NP_002183 NM_002192 ENSP00000242208 P08476 TRUE can 0 0 0 Metazoans 1 Cell cycle,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Immune system response,Multicellular activities,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction chr7 41729251 41739972 |NA| NP_002183 0 FALSE 1 17 1776 0.2500 4
3631 INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa 2q11.2 2949 6074 600916 NP_001127696;NP_001127697;NP_001557;NP_004018;XP_006712562;XP_006712563;XP_006712564;XP_006712565;XP_006712566;XP_006712567;XP_006712568;XP_006712569;XP_006712570;XP_006712571;XP_006712572 NM_001134224;NM_001134225;NM_001566;NM_004027;XM_006712499;XM_006712500;XM_006712501;XM_006712502;XM_006712503;XM_006712504;XM_006712505;XM_006712506;XM_006712507;XM_006712508;XM_006712509 ENSP00000074304 Q96PE3 TRUE can 0 0 0 Eukaryotes 0 Signal transduction chr2 99136512 99204068 |INPP4|TVAS1| NP_001127696 0 FALSE 1 4 81 0.0000
3660 IRF2 interferon regulatory factor 2 4q34.1-q35.1 962 6117 147576 NP_002190;XP_005263041;XP_005263043 NM_002199;XM_005262984;XM_005262986 ENSP00000377218 P14316 TRUE can 0 0 0 Metazoans 1 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr4 185309915 185350218 |IRF-2| NP_002190 0 FALSE 1 31 13121 0.1270
3662 IRF4 interferon regulatory factor 4 6p25-p23 3543 6119 601900 NP_001182215;NP_002451;XP_006715153 NM_001195286;NM_002460;NR_036585;NR_046000;XM_006715090 ENSP00000370343 Q15306 TRUE cgc 1 0 0 Metazoans 1 Cellular metabolism,DNA/RNA metabolism and transcription,Development,Immune system response,Regulation of intracellular processes and metabolism,Regulation of transcription chr6 393153 407595 |LSIRF|NF-EM5| NP_002451 0 FALSE 1 23 2751 0.0160
3664 IRF6 interferon regulatory factor 6 1q32.3-q41 6227 6121 607199 NP_001193625;NP_006138 NM_001206696;NM_006147 ENSP00000355988 O14896 TRUE can 0 0 0 - 1 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr1 209961768 209974758 |LPS|OFC6|PIT|PPS1|VWS| NP_006138 0 FALSE 1 7 187 0.0000
3667 IRS1 insulin receptor substrate 1 2q36 943 6125 147545 NP_005535;XP_005246591;XP_006712575 NM_005544;XM_005246534;XM_006712512 ENSP00000304895 P35568 TRUE can 0 0 0 Metazoans 7 Cell response to stimuli,Regulation of intracellular processes and metabolism,Signal transduction chr2 227659729 227663454 |HIRS-1| NP_005535 0 FALSE 1 96 45693 0.1390 9
3676 ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) 2q31.3 - 6140 192975 NP_000876 NM_000885 ENSP00000380227 P13612 TRUE can 0 0 0 Last Universal Common Ancestor 2 Cell motility and interactions,Development,Immune system response,Signal transduction chr2 182322382 182400251 |CD49D| NP_000876 0 FALSE 1 470 356323 0.0450 28
3702 ITK IL2-inducible T-cell kinase 5q31-q32 1746 6171 186973 NP_005537 NM_005546 ENSP00000398655 Q08881 TRUE cgc 1 0 0 Eukaryotes 0 Cell response to stimuli,Cellular metabolism,Cellular processes,Signal transduction chr5 156607989 156679685 |LPFS1|LYK| NP_005537 0 FALSE 2 39 4117 0.2520 5
3707 ITPKB inositol-trisphosphate 3-kinase B 1q42.13 942 6179 147522 NP_002212;XP_005273177 NM_002221;XM_005273120 ENSP00000272117 P27987 TRUE can 0 0 0 Opisthokonts 0 Signal transduction chr1 226822375 226925159 |IP3-3KB|IP3K|IP3K-B|IP3KB|PIG37| NP_002212 0 FALSE 1 5 491 0.1000
3716 JAK1 Janus kinase 1 1p32.3-p31.3 992 6190 147795 NP_002218;XP_005270898;XP_006710687 NM_002227;XM_005270841;XM_006710624 ENSP00000343204 P23458 TRUE cgc 1 0 0 Eukaryotes 4 Cellular metabolism,Cellular processes,Signal transduction chr1 65300248 65349161 |JAK1A|JAK1B|JTK3| NP_002218 0 FALSE 1 97 60965 0.1150 45
3717 JAK2 Janus kinase 2 9p24 993 6192 147796 NP_004963;XP_005251512 NM_004972;XM_005251455 ENSP00000371067 O60674 TRUE cgc 1 0 0 Last Universal Common Ancestor 4 Cell cycle,Cellular metabolism,Cellular processes,Development,Regulation of intracellular processes and metabolism,Signal transduction chr9 5021988 5126788 |JTK10|THCYT3| NP_004963 0 FALSE 2 118 62912 0.1150 58
3718 JAK3 Janus kinase 3 19p13.1 2547 6193 600173 NP_000206;XP_005259953;XP_006722808 NM_000215;XM_005259896;XM_006722745;XR_430137 ENSP00000391676 P52333 TRUE cgc 1 0 0 Eukaryotes 1 Cellular metabolism,Cellular processes chr19 17937555 17958870 |JAK-3|JAK3_HUMAN|JAKL|L-JAK|LJAK| XP_005259953 0 FALSE 1 61 12749 0.1150 18
3725 JUN jun proto-oncogene 1p32-p31 1302 6204 165160 NP_002219 NM_002228 ENSP00000360266 P05412 TRUE cgc 1 0 0 Metazoans 7 Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription chr1 59247750 59248742 |AP1|c-Jun| NP_002219 0 FALSE 1 223 226710 0.0720 17
3742 KCNA6 potassium voltage-gated channel, shaker-related subfamily, member 6 12p13 - 6225 176257 NP_002226;XP_005253743 NM_002235;XM_005253686 ENSP00000280684 P17658 TRUE can 0 0 1 Last Universal Common Ancestor 0 Cellular processes chr12 4919208 4920794 |HBK2|KV1.6|PPP1R96| NP_002226 1 FALSE 1 2 0 1.0000
3762 KCNJ5 potassium inwardly-rectifying channel, subfamily J, member 5 11q24 - 6266 600734 NP_000881;XP_005271600 NM_000890;XM_005271543 ENSP00000339960 P48544 TRUE cgc 1 0 1 Last Universal Common Ancestor 0 Cellular processes chr11 128781169 128786623 |GIRK4|KATP1|KIR3.4|LQT13| NP_000881 1 FALSE 1 4 38 0.5000 1
3791 KDR kinase insert domain receptor (a type III receptor tyrosine kinase) 4q11-q12 1867 6307 191306 NP_002244 NM_002253 ENSP00000263923 P35968 TRUE cgc 1 0 0 Eukaryotes 3 Cellular metabolism,Cellular processes,Development,Signal transduction chr4 55946111 55991460 |CD309|FLK1|VEGFR|VEGFR2| NP_002244 0 FALSE 2 64 45150 0.1090 42
3792 KEL Kell blood group, metallo-endopeptidase 7q33 194 6308 613883 NP_000411;XP_005250050;XP_005250051;XP_005250052;XP_005277045;XP_005277046;XP_005277047 NM_000420;XM_005249993;XM_005249994;XM_005249995;XM_005276988;XM_005276989;XM_005276990 ENSP00000347409;ENSP00000457677 P23276 TRUE can 0 0 0 Last Universal Common Ancestor 0 Cellular metabolism,Cellular processes,Development,Multicellular activities,Regulation of intracellular processes and metabolism chr7 142638342 142659160 |CD238|ECE3| XP_005250050 0 FALSE 1 8 9096 0.1430
3799 KIF5B kinesin family member 5B 10p11.22 7214 6324 602809 NP_004512 NM_004521 ENSP00000307078 P33176 TRUE cgc 1 0 0 Eukaryotes 12 Cellular processes chr10 32304460 32344901 |HEL-S-61|KINH|KNS|KNS1|UKHC| NP_004512 0 FALSE 1 84 28365 0.0730 5
3815 KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog 4q12 1287 6342 164920 NP_000213;NP_001087241;XP_005265797;XP_005265798;XP_005265799;XP_006714101 NM_000222;NM_001093772;XM_005265740;XM_005265741;XM_005265742;XM_006714038 ENSP00000288135 P10721 TRUE cgc 1 0 0 Eukaryotes 5 Cell cycle,Cellular metabolism,Cellular processes,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Signal transduction chr4 55524182 55604720 |C-Kit|CD117|PBT|SCFR| XP_005265797 0 FALSE 4 95 32717 0.1260 28
3817 KLK2 kallikrein-related peptidase 2 19q13.41 1006 6363 147960 NP_001002231;NP_001243009;NP_005542;XP_006723269;XP_006723270;XP_006723271;XP_006723272 NM_001002231;NM_001002232;NM_001256080;NM_005551;NR_045762;NR_045763;XM_006723206;XM_006723207;XM_006723208;XM_006723209 ENSP00000313581 P20151 TRUE cgc 1 0 1 Last Universal Common Ancestor 0 Cellular metabolism chr19 51376730 51381812 |KLK2A2|hGK-1|hK2| NP_005542 1 FALSE 1 16 11199 0.0670
3845 KRAS Kirsten rat sarcoma viral oncogene homolog 12p12.1 1817 6407 190070 NP_004976;NP_203524;XP_006719132 NM_004985;NM_033360;XM_006719069 ENSP00000309845 P01116 TRUE cgc 1 0 2 Last Universal Common Ancestor 14 Cell cycle,Cell response to stimuli,Cellular processes,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Signal transduction chr12 25368378 25398318 |C-K-RAS|CFC2|K-RAS2A|K-RAS2B|K-RAS4A|K-RAS4B|KI-RAS|KRAS1|KRAS2|NS3|RASK2| NP_203524 2 FALSE 16 58 49674 0.0240 17
3895 KTN1 kinectin 1 (kinesin receptor) 14q22.1 2661 6467 600381 NP_001072989;NP_001072990;NP_001257943;NP_004977;XP_006720201;XP_006720202;XP_006720203;XP_006720204 NM_001079521;NM_001079522;NM_001271014;NM_004986;NM_182926;NR_073128;NR_073129;XM_006720138;XM_006720139;XM_006720140;XM_006720141 ENSP00000378720 Q86UP2 TRUE cgc 1 0 0 Vertebrates 1 Cellular processes chr14 56078767 56146402 |KNT|MU-RMS-40.19| NP_001072989 0 FALSE 1 29 10410 0.0760 4
3899 AFF3 AF4/FMR2 family, member 3 2q11.2-q12 3272 6473 601464 NP_001020279;NP_002276;XP_005263999;XP_005264000;XP_005264002;XP_006712586 NM_001025108;NM_002285;XM_005263942;XM_005263943;XM_005263945;XM_006712523 ENSP00000348793 P51826 TRUE cgc 1 0 0 Metazoans 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr2 100167939 100722045 |LAF4|MLLT2-like| XP_005263999 0 FALSE 1 2 0 1.0000
3908 LAMA2 laminin, alpha 2 6q22-q23 1125 6482 156225 NP_000417;NP_001073291;XP_005267038;XP_005267039 NM_000426;NM_001079823;XM_005266981;XM_005266982 ENSP00000400365 P24043 TRUE can 0 0 0 Eukaryotes 0 Cell motility and interactions,Development chr6 129204391 129837489 |LAMM| XP_005267038 0 FALSE 1 4 34 0.1670 4
3910 LAMA4 laminin, alpha 4 6q21 2532 6484 600133 NP_001098676;NP_001098677;NP_001098678;NP_001098679;NP_002281;XP_005267040;XP_005267041;XP_006715543;XP_006715544 NM_001105206;NM_001105207;NM_001105208;NM_001105209;NM_002290;XM_005266983;XM_005266984;XM_006715480;XM_006715481 ENSP00000324532;ENSP00000462974 Q16363 TRUE can 0 0 0 Eukaryotes 3 Cell motility and interactions,Development chr6 112430643 112575352 |CMD1JJ|LAMA4*-1| NP_001098676 0 FALSE 2 18 1006 0.0980 5
3927 LASP1 LIM and SH3 protein 1 17q11-q21.3 4229 6513 602920 NP_001258537;NP_006139 NM_001271608;NM_006148;NR_073384 ENSP00000325240 Q14847 TRUE cgc 1 0 0 Eukaryotes 7 Cellular processes chr17 37026443 37075028 |Lasp-1|MLN50| NP_006139 0 FALSE 1 42 23177 0.0480
3932 LCK LCK proto-oncogene, Src family tyrosine kinase 1p34.3 1080 6524 153390 NP_001036236;NP_005347;XP_005270919;XP_005270920;XP_005270921 NM_001042771;NM_005356;XM_005270862;XM_005270863;XM_005270864 ENSP00000337825 P06239 TRUE cgc 1 0 0 Eukaryotes 1 Cell cycle,Cell response to stimuli,Cellular metabolism,Cellular processes,Development,Immune system response,Regulation of intracellular processes and metabolism,Signal transduction chr1 32739931 32751314 |IMD22|LSK|YT16|p56lck|pp58lck| XP_005270919 0 FALSE 1 141 90242 0.0830 45
3936 LCP1 lymphocyte cytosolic protein 1 (L-plastin) 13q14.3 1082 6528 153430 NP_002289;XP_005266431 NM_002298;XM_005266374 ENSP00000262709;ENSP00000315757 P13796 TRUE cgc 1 0 1 Eukaryotes 2 Cellular processes chr13 46701729 46733797 |CP64|HEL-S-37|L-PLASTIN|LC64P|PLS2| NP_002289 1 FALSE 1 8 1802 0.0360 1
3954 LETM1 leucine zipper-EF-hand containing transmembrane protein 1 4p16.3 5101 6556 604407 NP_036450;XP_005248027;XP_006713947 NM_012318;XM_005247970;XM_006713884 ENSP00000305653 O95202 TRUE can 0 0 2 Eukaryotes 4 Signal transduction chr4 1816154 1850937 |NA| NP_036450 2 FALSE 1 10 1383 0.1110
3977 LIFR leukemia inhibitory factor receptor alpha 5p13-p12 1048 6597 151443 NP_001121143;NP_002301 NM_001127671;NM_002310 ENSP00000263409 P42702 TRUE cgc 1 0 0 Vertebrates 10 Cell cycle,Regulation of intracellular processes and metabolism,Signal transduction chr5 38481700 38530749 |CD118|LIF-R|SJS2|STWS| NP_001121143 0 FALSE 1 13 7914 0.1410 3
4004 LMO1 LIM domain only 1 (rhombotin 1) 11p15 1738 6641 186921 NP_001257357;NP_002306;XP_006718291 NM_001270428;NM_002315;NR_073006;XM_006718228 ENSP00000338207 P25800 TRUE cgc 1 0 1 Eukaryotes 0 -1 chr11 8246166 8252052 |RBTN1|RHOM1| NP_002306 1 FALSE 1 37 7094 0.0410
4005 LMO2 LIM domain only 2 (rhombotin-like 1) 11p13 1586 6642 180385 NP_001135787;NP_001135788;NP_005565;XP_005252977;XP_005252978;XP_006718292 NM_001142315;NM_001142316;NM_005574;XM_005252920;XM_005252921;XM_006718229 ENSP00000257818 P25791 TRUE cgc 1 0 0 Eukaryotes 1 -1 chr11 33880905 33892633 |RBTN2|RBTNL1|RHOM2|TTG2| XP_005252977 0 FALSE 1 99 84715 0.0330 7
4009 LMX1A LIM homeobox transcription factor 1, alpha 1q24.1 2623 6653 600298 NP_001167540;NP_796372;XP_006711382 NM_001033507;NM_001174069;NM_177398;NM_177399;XM_006711319 ENSP00000294816 Q8TE12 TRUE can 0 0 0 Eukaryotes 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr1 165173120 165324796 |LMX1|LMX1.1| NP_001167540 0 FALSE 1 6 1626 0.2670
4026 LPP LIM domain containing preferred translocation partner in lipoma 3q28 2828 6679 600700 NP_001161143;NP_001161144;NP_005569;XP_005247501;XP_005247502;XP_005247503;XP_005247504;XP_005247505;XP_005247507;XP_005247508;XP_005247510;XP_006713700 NM_001167671;NM_001167672;NM_005578;XM_005247444;XM_005247445;XM_005247446;XM_005247447;XM_005247448;XM_005247450;XM_005247451;XM_005247453;XM_006713637 ENSP00000318089 Q93052 TRUE cgc 1 0 0 Eukaryotes 3 -1 chr3 187964917 188592264 |NA| XP_005247501 0 FALSE 1 46 11758 0.1200
4036 LRP2 low density lipoprotein receptor-related protein 2 2q31.1 2509 6694 600073 NP_004516;XP_006712589;XP_006712590;XP_006712591 NM_004525;XM_006712526;XM_006712527;XM_006712528 ENSP00000263816 P98164 TRUE can 0 0 0 Metazoans 0 Cellular metabolism,Cellular processes,Development chr2 169985176 170218909 |GP330| NP_004516 0 TRUE 3 48 32003 0.0370
4048 LTA4H leukotriene A4 hydrolase 12q22 1056 6710 151570 NP_000886;NP_001243572;NP_001243573;XP_005268928 NM_000895;NM_001256643;NM_001256644;XM_005268871 ENSP00000228740 P09960 TRUE can 0 0 0 Last Universal Common Ancestor 4 Cellular metabolism,Immune system response chr12 96394770 96429297 |NA| NP_000886 0 FALSE 1 13 2628 0.0380
4058 LTK leukocyte receptor tyrosine kinase 15q15.1-q21.1 1052 6721 151520 NP_001129157;NP_002335;NP_996844;XP_005254438;XP_005254439;XP_006720568 NM_001135685;NM_002344;NM_206961;XM_005254381;XM_005254382;XM_006720505 ENSP00000263800 P29376 TRUE can 0 0 0 Eukaryotes 1 Cellular metabolism,Cellular processes,Signal transduction chr15 41796197 41805907 |TYK1| NP_002335 0 FALSE 2 9 57 0.2220 1
4060 LUM lumican 12q21.33 - 6724 600616 NP_002336 NM_002345 ENSP00000266718 P51884 TRUE can 0 0 0 Eukaryotes 0 Cell motility and interactions,Cell response to stimuli,Cellular processes chr12 91497945 91502756 |LDC|SLRR2D| NP_002336 0 FALSE 1 5 665 0.1000 2
4066 LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1 19p13.2 1046 6734 151440 NP_005574;XP_005259969;XP_006722815;XP_006722816;XP_006722817 NM_005583;XM_005259912;XM_006722752;XM_006722753;XM_006722754 ENSP00000264824 P12980 TRUE cgc 1 0 0 Metazoans 1 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr19 13210136 13211985 |bHLHa18| NP_005574 0 FALSE 1 9 103 0.3060
4087 SMAD2 SMAD family member 2 18q21.1 3221 6768 601366 NP_001003652;NP_001129409;NP_005892;XP_005258316;XP_006722514 NM_001003652;NM_001135937;NM_005901;XM_005258259;XM_006722451 ENSP00000262160 Q15796 TRUE can 0 0 1 Metazoans 3 Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction chr18 45368201 45423127 |JV18|JV18-1|MADH2|MADR2|hMAD-2|hSMAD2| NP_001003652 1 FALSE 2 369 543610 0.0300 47
4089 SMAD4 SMAD family member 4 18q21.1 2995 6770 600993 NP_005350 NM_005359 ENSP00000341551 Q13485 TRUE cgc 0 1 0 Metazoans 19 Cell cycle,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction chr18 48573417 48604834 |DPC4|JIP|MADH4|MYHRS| NP_005350 0 FALSE 8 241 309758 0.0400 57
4094 MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog 16q22-q23 1518 6776 177075 NP_001026974;NP_005351 NM_001031804;NM_005360 ENSP00000327048 O75444 TRUE cgc 1 0 0 Metazoans 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr16 79628360 79633799 |CCA4|c-MAF| NP_005351 0 FALSE 1 22 1860 0.2640
4105 MAGEA6 melanoma antigen family A, 6 Xq28 2168 6804 300176 NP_005354;NP_787064 NM_005363;NM_175868 ENSP00000333487;ENSP00000359307;ENSP00000470872;ENSP00000472505 P43360 TRUE can 0 0 6 Eukaryotes 2 -1 chrX 151869311 151870252 |CT1.6|MAGE-3b|MAGE3B|MAGE6| NP_005354 6 FALSE 1 74 52413 0.0110
4149 MAX MYC associated factor X 14q23 1113 6913 154950 NP_001257997;NP_001257998;NP_002373;NP_660087;NP_660088;NP_660089;NP_932061 NM_001271068;NM_001271069;NM_002382;NM_145112;NM_145113;NM_145114;NM_145116;NM_197957;NR_073137;NR_073138;XR_429315 ENSP00000351490 P61244 TRUE cgc 0 0 0 Metazoans 1 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr14 65543197 65560533 |bHLHd4| NP_002373 0 FALSE 1 89 57587 0.0510 7
4193 MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 12q14.3-q15 - 6973 164785 NP_001138809;NP_001138811;NP_001138812;NP_001265391;NP_002383;XP_005268929;XP_006719462;XP_006719463 NM_001145336;NM_001145337;NM_001145339;NM_001145340;NM_001278462;NM_002392;NM_006878;NM_006879;NM_006880;NM_006881;NM_006882;NM_032739;XM_005268872;XM_006719399;XM_006719400 ENSP00000417281 Q00987 TRUE cgc 1 0 0 Metazoans 7 Cell cycle,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr12 69202986 69233626 |ACTFS|hdm2| NP_002383 0 FALSE 1 749 1400662 0.0290 21
4194 MDM4 MDM4, p53 regulator 1q32 4082 6974 602704 NP_001191100;NP_001191101;NP_001265445;NP_001265446;NP_001265447;NP_001265448;NP_002384;XP_006711391;XP_006711392 NM_001204171;NM_001204172;NM_001278516;NM_001278517;NM_001278518;NM_001278519;NM_002393;XM_006711328;XM_006711329;XR_241079;XR_426774;XR_426775 ENSP00000356150 O15151 TRUE cgc 1 0 0 Vertebrates 7 Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr1 204494647 204518807 |MDMX| NP_002384 0 FALSE 1 58 22447 0.1740 2
4208 MEF2C myocyte enhancer factor 2C 5q14.3 2809 6996 600662 NP_001124477;NP_001180276;NP_001180277;NP_001180278;NP_001180279;NP_002388;XP_005248568;XP_006714681;XP_006714682;XP_006714683;XP_006714684;XP_006714685;XP_006714686;XP_006714687;XP_006714688 NM_001131005;NM_001193347;NM_001193348;NM_001193349;NM_001193350;NM_002397;XM_005248511;XM_006714618;XM_006714619;XM_006714620;XM_006714621;XM_006714622;XM_006714623;XM_006714624;XM_006714625 ENSP00000346389 Q06413 TRUE can 0 0 0 Eukaryotes 3 Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription chr5 88018424 88119605 |C5DELq14.3|DEL5q14.3| NP_001180276 0 FALSE 2 35 18026 0.1290 3
4214 MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase 5q11.2 - 6848 600982 NP_005912;XP_005248576;XP_005248577 NM_005921;XM_005248519;XM_005248520 ENSP00000382423 Q13233 TRUE can 0 0 0 Eukaryotes 2 Cellular metabolism,Cellular processes,Signal transduction chr5 56111401 56189504 |MAPKKK1|MEKK|MEKK 1|MEKK1|SRXY6| NP_005912 0 FALSE 1 203 124410 0.0560 2
4216 MAP3K4 mitogen-activated protein kinase kinase kinase 4 6q26 3886 6856 602425 NP_005913;NP_006715;XP_005267045;XP_005267046 NM_005922;NM_006724;XM_005266988;XM_005266989;XR_245517 ENSP00000375986 Q9Y6R4 TRUE can 0 0 0 Eukaryotes 3 Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism,Signal transduction chr6 161412964 161536337 |MAPKKK4|MEKK 4|MEKK4|MTK1|PRO0412| NP_005913 0 FALSE 1 32 3972 0.0890 2
4217 MAP3K5 mitogen-activated protein kinase kinase kinase 5 6q22.33 3904 6857 602448 NP_005914;XP_005267047;XP_005267048;XP_005267049;XP_006715545 NM_005923;XM_005266990;XM_005266991;XM_005266992;XM_006715482 ENSP00000351908 Q99683 TRUE can 0 0 0 Last Universal Common Ancestor 0 Cell cycle,Cellular metabolism,Cellular processes,Development,Regulation of intracellular processes and metabolism,Signal transduction chr6 136878899 137113295 |ASK1|MAPKKK5|MEKK5| XP_005267048 0 FALSE 1 88 44195 0.0890 3
4221 MEN1 multiple endocrine neoplasia I 11q13 564 7010 613733 NP_000235;NP_570711;NP_570712;NP_570713;NP_570714;NP_570715;NP_570716;XP_005274058;XP_005274059;XP_005274060;XP_006718620 NM_000244;NM_130799;NM_130800;NM_130801;NM_130802;NM_130803;NM_130804;XM_005274001;XM_005274002;XM_005274003;XM_006718557 ENSP00000337088 O00255 TRUE cgc 0 1 0 Metazoans 0 Cell cycle,Cell response to stimuli,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction chr11 64571809 64577581 |MEAI| NP_000235 0 FALSE 4 58 19848 0.1500 6
4224 MEP1A meprin A, alpha (PABA peptide hydrolase) 6p12-p11 2666 7015 600388 NP_005579 NM_005588 ENSP00000230588 Q16819 TRUE can 0 0 0 Eukaryotes 1 Cellular metabolism chr6 46761136 46806870 |PPHA| NP_005579 0 FALSE 1 20 34503 0.0680 1
4233 MET MET proto-oncogene, receptor tyrosine kinase 7q31 1280 7029 164860 NP_000236;NP_001120972;XP_006716051;XP_006716052;XP_006716053;XP_006716054 NM_000245;NM_001127500;XM_006715988;XM_006715989;XM_006715990;XM_006715991 ENSP00000262173;ENSP00000317272;ENSP00000369887 P08581 TRUE cgc 1 0 0 Last Universal Common Ancestor 17 Cell cycle,Cell motility and interactions,Cellular metabolism,Cellular processes,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Signal transduction chr7 116339139 116436175 |AUTS9|HGFR|c-Met| NP_001120972 0 FALSE 5 114 68508 0.0960 7
4261 CIITA class II, major histocompatibility complex, transactivator 16p13 2475 7067 600005 NP_000237;NP_001273331;NP_001273332;XP_005255377;XP_005255378;XP_005255380;XP_006720943;XP_006720944;XP_006720945;XP_006720946 NM_000246;NM_001286402;NM_001286403;NR_104444;XM_005255320;XM_005255321;XM_005255323;XM_006720880;XM_006720881;XM_006720882;XM_006720883 ENSP00000316328 P33076 TRUE cgc 1 0 0 Eukaryotes 1 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr16 10972803 11017157 |C2TA|CIITAIV|MHC2TA|NLRA| XP_005255377 0 FALSE 1 28 9928 0.1510
4286 MITF microphthalmia-associated transcription factor 3p14.2-p14.1 1138 7105 156845 NP_000239;NP_001171896;NP_001171897;NP_006713;NP_937801;NP_937802;NP_937820;NP_937821;XP_005264811;XP_005264812;XP_006713227 NM_000248;NM_001184967;NM_001184968;NM_006722;NM_198158;NM_198159;NM_198177;NM_198178;XM_005264754;XM_005264755;XM_006713164 ENSP00000295600 O75030 TRUE cgc 1 0 0 Metazoans 5 Cell response to stimuli,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription chr3 69788749 70014396 |MI|WS2|WS2A|bHLHe32| XP_005264811 0 FALSE 1 30 13794 0.1200 1
4288 MKI67 marker of proliferation Ki-67 10q26.2 8902 7107 176741 NP_001139438;NP_002408;XP_006717927 NM_001145966;NM_002417;XM_006717864 ENSP00000357643 P46013 TRUE can 0 0 0 Metazoans 7 -1 chr10 129897457 129923931 |KIA|MIBMIB-1|PPP1R105| NP_002408 0 FALSE 1 29 6571 0.1820 1
4291 MLF1 myeloid leukemia factor 1 3q25.1 3239 7125 601402 NP_001123628;NP_001123629;NP_001182361;NP_001182362;NP_001182363;NP_071888;XP_005247536;XP_005247537;XP_006713708 NM_001130156;NM_001130157;NM_001195432;NM_001195433;NM_001195434;NM_022443;XM_005247479;XM_005247480;XM_006713645 ENSP00000376568 P58340 TRUE cgc 1 0 0 Metazoans 0 Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Development chr3 158310221 158322988 |NA| NP_001182361 0 FALSE 1 67 18575 0.0900
4292 MLH1 mutL homolog 1 3p21.3 390 7127 120436 NP_000240;NP_001161089;NP_001161090;NP_001161091;NP_001245200;NP_001245202;NP_001245203;XP_005265218;XP_005265220;XP_005265221;XP_005265223 NM_000249;NM_001167617;NM_001167618;NM_001167619;NM_001258271;NM_001258273;NM_001258274;XM_005265161;XM_005265163;XM_005265164;XM_005265166;XR_427268 ENSP00000231790 P40692 TRUE cgc 0 1 0 Last Universal Common Ancestor 3 Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism chr3 37035039 37092141 |COCA2|FCC2|HNPCC2|hMLH1| NP_000240 0 FALSE 2 152 184705 0.0270 27
4293 MAP3K9 mitogen-activated protein kinase kinase kinase 9 14q24.2 15965 6861 600136 NP_001271159;NP_001271160;NP_001271161;NP_149132;XP_005267740;XP_006720212;XP_006720213 NM_001284230;NM_001284231;NM_001284232;NM_033141;XM_005267683;XM_006720149;XM_006720150 ENSP00000451263 P80192 TRUE can 0 0 0 Eukaryotes 1 Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism,Signal transduction chr14 71197100 71275888 |MEKK9|MLK1|PRKE1| NP_149132 0 FALSE 1 3 35 0.3330
4297 KMT2A lysine (K)-specific methyltransferase 2A 11q23 1162 7132 159555 NP_001184033;NP_005924;XP_006718902;XP_006718903 NM_001197104;NM_005933;NM_024891;XM_006718839;XM_006718840 ENSP00000472616 Q03164 TRUE cgc 1 0 0 Last Universal Common Ancestor 5 Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription chr11 118307228 118392884 |ALL-1|CXXC7|HTRX1|MLL|MLL1|MLL1A|TET1-MLL|WDSTS| NP_001184033 0 FALSE 5 76 23149 0.1050 5
4298 MLLT1 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1 19p13.3 15933 7134 159556 NP_005925;XP_005259618 NM_005934;XM_005259561 ENSP00000252674 Q03111 TRUE cgc 1 0 0 Eukaryotes 3 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr19 6213056 6270773 |ENL|LTG19|YEATS1| NP_005925 0 FALSE 1 28 1314 0.2060 4
4299 AFF1 AF4/FMR2 family, member 1 4q21 8871 7135 159557 NP_001160165;NP_005926;XP_005263064;XP_005263065;XP_005263066;XP_005263067;XP_005263068;XP_005263069;XP_005263070 NM_001166693;NM_005935;XM_005263007;XM_005263008;XM_005263009;XM_005263010;XM_005263011;XM_005263012;XM_005263013 ENSP00000378578 P51825 TRUE cgc 1 0 0 Metazoans 1 -1 chr4 87967313 88056850 |AF4|MLLT2|PBM1| NP_001160165 0 FALSE 1 26 2430 0.2060 1
4300 MLLT3 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 9p22 1163 7136 159558 NP_001273620;NP_004520 NM_001286691;NM_004529 ENSP00000369695 P42568 TRUE cgc 1 0 0 Eukaryotes 3 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr9 20346444 20620833 |AF9|YEATS3| NP_004520 0 FALSE 1 37 13797 0.1140
4301 MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 6q27 1164 7137 159559 NP_001035089;NP_001193937;XP_005267053;XP_005267054;XP_006715546;XP_006715547;XP_006715548;XP_006715549;XP_006715550;XP_006715551;XP_006715552;XP_006715553;XP_006715554;XP_006715555;XP_006715556;XP_006715557 NM_001040000;NM_001040001;NM_001207008;NM_005936;XM_005266996;XM_005266997;XM_006715483;XM_006715484;XM_006715485;XM_006715486;XM_006715487;XM_006715488;XM_006715489;XM_006715490;XM_006715491;XM_006715492;XM_006715493;XM_006715494;XR_427971 ENSP00000375956 P55196 TRUE cgc 1 0 0 Metazoans 4 Signal transduction chr6 168227813 168370612 |AF6| XP_005267053 0 FALSE 1 58 47990 0.1010 1
4302 MLLT6 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6 17q21 8978 7138 600328 NP_005928;XP_005257436;XP_005257437;XP_005257438;XP_006721973;XP_006721974;XP_006725387;XP_006725388;XP_006725389;XP_006725390;XP_006725391 NM_005937;XM_005257379;XM_005257380;XM_005257381;XM_006721910;XM_006721911;XM_006725324;XM_006725325;XM_006725326;XM_006725327;XM_006725328;XR_429892;XR_430782 ENSP00000316426 P55198 TRUE cgc 1 0 0 Eukaryotes 5 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr17 36861886 36881848 |AF17| XP_005257436 0 FALSE 1 23 14110 0.0590
4303 FOXO4 forkhead box O4 Xq13.1 2070 7139 300033 NP_001164402;NP_005929 NM_001170931;NM_005938 ENSP00000363377 P98177 TRUE cgc 1 0 0 Eukaryotes 1 Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction chrX 70316379 70321589 |AFX|AFX1|MLLT7| NP_005929 0 FALSE 1 20 1150 0.2580 1
4306 NR3C2 nuclear receptor subfamily 3, group C, member 2 4q31.1 2991 7979 600983 NP_000892;NP_001159576;XP_005263071;XP_006714285 NM_000901;NM_001166104;XM_005263014;XM_006714222 ENSP00000341390 P08235 TRUE can 0 0 0 Eukaryotes 9 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction chr4 149002498 149358012 |MCR|MLR|MR|NR3C2VIT| NP_000892 0 FALSE 1 28 2616 0.2060 3
4322 MMP13 matrix metallopeptidase 13 (collagenase 3) 11q22.3 2522 7159 600108 NP_002418 NM_002427 ENSP00000260302;ENSP00000460695 P45452 TRUE can 0 0 0 Eukaryotes 10 Cellular metabolism chr11 102814998 102826434 |CLG3|MANDP1|MMP-13| NP_002418 0 FALSE 1 8 7006 0.1430 1
4330 MN1 meningioma (disrupted in balanced translocation) 1 22q12.1 8862 7180 156100 NP_002421 NM_002430 ENSP00000304956 Q10571 TRUE cgc 1 0 0 Vertebrates 4 Cell cycle,Regulation of intracellular processes and metabolism chr22 28146906 28196531 |MGCR|MGCR1|MGCR1-PEN| NP_002421 0 FALSE 1 2 0 1.0000
4331 MNAT1 MNAT CDK-activating kinase assembly factor 1 14q23 4042 7181 602659 NP_001171434;NP_002422;XP_005267744;XP_005267745 NM_001177963;NM_002431;XM_005267687;XM_005267688 ENSP00000261245 P51948 TRUE can 0 0 0 Eukaryotes 1 Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction chr14 61201581 61435064 |CAP35|RNF66|TFB3| NP_002422 0 FALSE 1 52 8080 0.1090 30
4342 MOS v-mos Moloney murine sarcoma viral oncogene homolog 8q11 1816 7199 190060 NP_005363 NM_005372 ENSP00000261326;ENSP00000357754 P00540 TRUE can 0 0 0 Last Universal Common Ancestor 0 Cellular metabolism,Cellular processes chr8 57025504 57026541 |MSV| NP_005363 0 FALSE 1 48 21922 0.0870
4352 MPL MPL proto-oncogene, thrombopoietin receptor 1p34 - 7217 159530 NP_005364 NM_005373 ENSP00000361548 P40238 TRUE cgc 1 0 0 Vertebrates 0 Signal transduction chr1 43803520 43818440 |C-MPL|CD110|MPLV|THCYT2|TPOR| NP_005364 0 FALSE 1 10 816 0.2440 1
4430 MYO1B myosin IB 2q12-q34 8407 7596 606537 NP_001123630;NP_001155291;NP_036355;XP_005246626;XP_005246629;XP_005246632;XP_005246634;XP_006712599;XP_006712600 NM_001130158;NM_001161819;NM_012223;XM_005246569;XM_005246572;XM_005246575;XM_005246577;XM_006712536;XM_006712537 ENSP00000306382 O43795 TRUE can 0 0 0 Eukaryotes 2 -1 chr2 192112684 192288683 |myr1| XP_005246626 0 FALSE 2 26 1895 0.1080
4436 MSH2 mutS homolog 2 2p21 389 7325 609309 NP_000242;NP_001245210;XP_005264389 NM_000251;NM_001258281;XM_005264332 ENSP00000233146 P43246 TRUE cgc 0 1 0 Last Universal Common Ancestor 8 Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism chr2 47630331 47710085 |COCA1|FCC1|HNPCC1|LCFS2| NP_000242 0 FALSE 2 109 27295 0.1000 33
4437 MSH3 mutS homolog 3 5q11-q12 2931 7326 600887 NP_002430 NM_002439 ENSP00000265081 P20585 TRUE can 0 0 0 Last Universal Common Ancestor 1 Cellular metabolism,DNA/RNA metabolism and transcription,Development,Immune system response chr5 79950547 80171678 |NA| NP_002430 0 FALSE 1 22 1565 0.2940 5
4478 MSN moesin Xq11.1 2399 7373 309845 NP_002435;XP_005262326 NM_002444;XM_005262269 ENSP00000353408 P26038 TRUE cgc 1 0 2 Eukaryotes 2 Cell motility and interactions,Immune system response chrX 64936680 64959752 |HEL70| XP_005262326 2 FALSE 1 83 35704 0.0940 1
4481 MSR1 macrophage scavenger receptor 1 8p22 1092 7376 153622 NP_002436;NP_619729;NP_619730 NM_002445;NM_138715;NM_138716 ENSP00000262101 P21757 TRUE can 0 0 0 Metazoans 0 Cellular processes chr8 15967597 16035497 |CD204|SCARA1|SR-A|phSR1|phSR2| NP_619729 0 FALSE 2 9 3609 0.0000 2
4485 MST1 macrophage stimulating 1 (hepatocyte growth factor-like) 3p21 798 7380 142408 NP_066278;XP_006713229;XP_006713230;XP_006713231;XP_006713232 NM_020998;XM_006713166;XM_006713167;XM_006713168;XM_006713169;XR_427269;XR_427270;XR_427271;XR_427272;XR_427273;XR_427274;XR_427275;XR_427276 ENSP00000414287 P26927 TRUE can 0 0 2 Eukaryotes 1 Cellular metabolism,Multicellular activities chr3 49721464 49726124 |NF15S2| NP_066278 2 FALSE 1 12 977 0.0450
4486 MST1R macrophage stimulating 1 receptor (c-met-related tyrosine kinase) 3p21.3 2545 7381 600168 NP_001231866;NP_002438;XP_005265227 NM_001244937;NM_002447;XM_005265170;XR_245136 ENSP00000296474 Q04912 TRUE can 0 0 0 Eukaryotes 0 Cell cycle,Cellular metabolism,Cellular processes,Development,Regulation of intracellular processes and metabolism,Signal transduction chr3 49924743 49941042 |CD136|CDw136|PTK8|RON| XP_005265227 0 FALSE 1 28 10680 0.2940
4513 COX2 cytochrome c oxidase subunit II - - - 516040 YP_003024029 - ENSP00000354876;ENSP00000356438 P00403 TRUE can 0 0 -1 Last Universal Common Ancestor 3 Cellular metabolism,Cellular processes - 0 0 |COII|MTCO2|MT-CO2| - -1 FALSE 1
4515 MTCP1 mature T-cell proliferation 1 Xq28 2122 7423 300116 NP_001018025 NM_001018025;NM_014221 ENSP00000358491;ENSP00000471104 P56278 TRUE cgc 1 0 0 Eukaryotes 1 -1 chrX 154293768 154294285 |P13MTCP1| NP_001018025 0 FALSE 1 5 913 0.4000
4582 MUC1 mucin 1, cell surface associated 1q21 1152 7508 158340 NP_001018016;NP_001018017;NP_001037855;NP_001037856;NP_001037857;NP_001037858;NP_001191214;NP_001191215;NP_001191216;NP_001191217;NP_001191218;NP_001191219;NP_001191220;NP_001191221;NP_001191222;NP_001191223;NP_001191224;NP_001191225;NP_001191226;NP_002447 NM_001018016;NM_001018017;NM_001018021;NM_001044390;NM_001044391;NM_001044392;NM_001044393;NM_001204285;NM_001204286;NM_001204287;NM_001204288;NM_001204289;NM_001204290;NM_001204291;NM_001204292;NM_001204293;NM_001204294;NM_001204295;NM_001204296;NM_001204297;NM_002456;NM_182741 ENSP00000255389;ENSP00000357380 P15941 TRUE cgc 1 0 0 Vertebrates 9 -1 chr1 155158614 155162634 |ADMCKD|ADMCKD1|CA 15-3|CD227|H23AG|KL-6|MAM6|MCKD|MCKD1|MUC-1|MUC-1/SEC|MUC-1/X|MUC1/ZD|PEM| NP_001191215 0 FALSE 1 40 29949 0.1740
4583 MUC2 mucin 2, oligomeric mucus/gel-forming 11p15.5 - 7512 158370 NP_002448 NM_002457 ENSP00000415183 Q02817 TRUE can 0 0 0 Eukaryotes 0 Multicellular activities chr11 1074902 1104260 |MUC-2| NP_002448 0 FALSE 1 5 4491 0.1000
4585 MUC4 mucin 4, cell surface associated 3q29 11829 7514 158372 NP_004523;NP_060876;NP_612154 NM_004532;NM_018406;NM_138297;NM_138298;NM_138299 ENSP00000417498 Q99102 TRUE can 0 0 0 Metazoans 2 Cell motility and interactions chr3 195474050 195518372 |ASGP|HSA276359|MUC-4| NP_060876 0 TRUE 1 2 14562 0.0000
4588 MUC6 mucin 6, oligomeric mucus/gel-forming 11p15.5 - 7517 158374 NP_005952;XP_006725595;XP_006725823 NM_005961;XM_006725532;XM_006725760 ENSP00000406861 Q6W4X9 TRUE can 0 0 0 Eukaryotes 1 Multicellular activities chr11 1013459 1036655 |MUC-6| NP_005952 0 FALSE 1 1 0 0.0000
4595 MUTYH mutY homolog 1p34.1 5380 7527 604933 NP_001041636;NP_001041637;NP_001041638;NP_001041639;NP_001121897;NP_036354;XP_005270937;XP_005270938;XP_005270941;XP_005270942;XP_006710711;XP_006710712;XP_006710713;XP_006710714;XP_006710715 NM_001048171;NM_001048172;NM_001048173;NM_001048174;NM_001128425;NM_012222;XM_005270880;XM_005270881;XM_005270884;XM_005270885;XM_006710648;XM_006710649;XM_006710650;XM_006710651;XM_006710652 ENSP00000361170 Q9UIF7 TRUE cgc 0 1 0 Last Universal Common Ancestor 0 Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism chr1 45794981 45800183 |MYH| NP_001121897 0 FALSE 1 19 1445 0.0940
4602 MYB v-myb avian myeloblastosis viral oncogene homolog 6q22-q23 1810 7545 189990 NP_001123644;NP_001123645;NP_001155128;NP_001155129;NP_001155130;NP_001155131;NP_001155132;NP_005366;XP_006715558 NM_001130172;NM_001130173;NM_001161656;NM_001161657;NM_001161658;NM_001161659;NM_001161660;NM_005375;XM_006715495 ENSP00000339992 P10242 TRUE cgc 1 0 0 Eukaryotes 14 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr6 135507039 135539115 |Cmyb|c-myb|c-myb_CDS|efg| NP_001123645 0 FALSE 2 73 38133 0.0830
4603 MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1 8q13.1 - 7547 159405 NP_001073885;NP_001138227;XP_005251308;XP_006716513;XP_006716514;XP_006716515 NM_001080416;NM_001144755;XM_005251251;XM_006716450;XM_006716451;XM_006716452 ENSP00000429633 P10243 TRUE can 0 0 0 Eukaryotes 5 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr8 67476935 67514760 |A-MYB|AMYB| NP_001073885 0 FALSE 1 7 82 0.2860
4609 MYC v-myc avian myelocytomatosis viral oncogene homolog 8q24.21 1818 7553 190080 NP_002458 NM_002467 ENSP00000367207 P01106 TRUE cgc 1 0 0 Metazoans 24 Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr8 128750491 128753201 |MRTL|MYCC|bHLHe39|c-Myc| NP_002458 0 FALSE 3 560 863288 0.0270 8
4610 MYCL v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog 1p34.2 1279 7555 164850 NP_001028253;NP_001028254;NP_005367 NM_001033081;NM_001033082;NM_005376 ENSP00000380494 P12524 TRUE cgc 1 0 1 Vertebrates 1 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr1 40363047 40367560 |LMYC|MYCL1| NP_001028254 1 FALSE 1 2 0 1.0000
4613 MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog 2p24.3 1278 7559 164840 NP_005369;XP_006711949 NM_005378;XM_006711886 ENSP00000281043 P04198 TRUE cgc 1 0 0 Metazoans 12 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr2 16082187 16086216 |MODED|N-myc|NMYC|ODED|bHLHe37| NP_005369 0 FALSE 2 24 1561 0.1630
4615 MYD88 myeloid differentiation primary response 88 3p22 3703 7562 602170 NP_001166037;NP_001166038;NP_001166039;NP_001166040;NP_002459;XP_005265229;XP_006713233 NM_001172566;NM_001172567;NM_001172568;NM_001172569;NM_002468;XM_005265172;XM_006713170 ENSP00000401399 Q99836 TRUE cgc 1 0 0 Metazoans 1 Cell cycle,Cell response to stimuli,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Immune system response,Multicellular activities,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction chr3 38180153 38182774 |MYD88D| NP_001166038 0 FALSE 1 60 25987 0.0750 44
4620 MYH2 myosin, heavy chain 2, skeletal muscle, adult 17p13.1 1173 7572 160740 NP_001093582;NP_060004 NM_001100112;NM_017534 ENSP00000245503 Q9UKX2 TRUE can 0 0 7 Eukaryotes 1 Cellular processes,Multicellular activities chr17 10424600 10451237 |IBM3|MYH2A|MYHSA2|MYHas8|MyHC-2A|MyHC-IIa| NP_001093582 7 FALSE 1 12 596 0.0300 1
4622 MYH4 myosin, heavy chain 4, skeletal muscle 17p13.1 8873 7574 160742 NP_060003;XP_005256707 NM_017533;XM_005256650 ENSP00000255381 Q9Y623 TRUE can 0 0 7 Eukaryotes 1 Cellular processes,Multicellular activities chr17 10346695 10370062 |MYH2B|MyHC-2B|MyHC-IIb| XP_005256707 7 FALSE 1 6 68 0.0000
4627 MYH9 myosin, heavy chain 9, non-muscle 22q13.1 1177 7579 160775 NP_002464 NM_002473 ENSP00000216181 P35579 TRUE cgc 1 0 2 Eukaryotes 6 Cell motility and interactions,Cell response to stimuli,Cellular metabolism,Cellular processes,Development,Immune system response,Regulation of intracellular processes and metabolism,Signal transduction chr22 36678717 36745281 |BDPLT6|DFNA17|EPSTS|FTNS|MHA|NMHC-II-A|NMMHC-IIA|NMMHCA| NP_002464 2 FALSE 1 120 74350 0.1080 6
4629 MYH11 myosin, heavy chain 11, smooth muscle 16p13.11 1174 7569 160745 NP_001035202;NP_001035203;NP_002465;NP_074035 NM_001040113;NM_001040114;NM_002474;NM_022844 ENSP00000379616 P35749 TRUE cgc 1 0 2 Eukaryotes 0 Cell cycle,Cell motility and interactions,Cellular processes,Development,Multicellular activities chr16 15797851 15932109 |AAT4|FAA4|SMHC|SMMHC| NP_001035203 2 FALSE 1 22 3100 0.1650 5
4649 MYO9A myosin IXA 15q22-q23 5341 7608 604875 NP_008832;XP_005254461;XP_006720602;XP_006720603;XP_006720604 NM_006901;XM_005254404;XM_006720539;XM_006720540;XM_006720541 ENSP00000348349 B2RTY4 TRUE can 0 0 0 Eukaryotes 6 Cell response to stimuli,Signal transduction chr15 72118924 72338904 |NA| XP_005254461 0 FALSE 1 6 298 0.0000
4654 MYOD1 myogenic differentiation 1 11p15.4 1166 7611 159970 NP_002469 NM_002478 ENSP00000250003 P15172 TRUE can 0 0 0 Metazoans 1 Cell cycle,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription chr11 17741330 17743052 |MYF3|MYOD|bHLHc1| NP_002469 0 FALSE 1 82 46274 0.1100 5
4666 NACA nascent polypeptide-associated complex alpha subunit 12q23-q24.1 3137 7629 601234 NP_001106673;NP_001106674;XP_006719475;XP_006719476;XP_006719477;XP_006719478;XP_006719479;XP_006719480;XP_006719481;XP_006719482;XP_006719483;XP_006719484 NM_001113201;NM_001113202;NM_001113203;NM_005594;NR_045277;XM_006719412;XM_006719413;XM_006719414;XM_006719415;XM_006719416;XM_006719417;XM_006719418;XM_006719419;XM_006719420;XM_006719421 ENSP00000427802 Q13765 TRUE cgc 1 0 0 Last Universal Common Ancestor 2 Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Regulation of transcription chr12 57106570 57118305 |NACA1|skNAC| NP_001106674 0 FALSE 1 33 6840 0.0810
4683 NBN nibrin 8q21 4050 7652 602667 NP_002476;XP_005250980 NM_001024688;NM_002485;XM_005250923;XR_242390;XR_242391 ENSP00000265433;ENSP00000387435 O60934 TRUE cgc 0 1 0 Metazoans 3 Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction chr8 90949253 90996789 |AT-V1|AT-V2|ATV|P95| NP_002476 0 FALSE 1 72 9313 0.1590 27
4685 NCAM2 neural cell adhesion molecule 2 21q21.1 - 7657 602040 NP_004531;XP_005261045;XP_006724070;XP_006724071;XP_006724072 NM_004540;XM_005260988;XM_006724007;XM_006724008;XM_006724009 ENSP00000298231 O15394 TRUE can 0 0 0 Metazoans 2 Cell motility and interactions chr21 22370882 22910275 |NCAM21| NP_004531 0 FALSE 1 3 52 0.0000
4703 NEB nebulin 2q22 1196 7720 161650 NP_001157979;NP_001157980;NP_001258137;NP_004534;XP_005246647;XP_005246648;XP_005246649;XP_005246650;XP_005246651;XP_005246652;XP_005246653;XP_005246654;XP_005246655;XP_005246656;XP_005246657;XP_005246658;XP_005246659;XP_005246660;XP_005246661;XP_005246663;XP_005246665;XP_005246667;XP_005246668;XP_005246669;XP_005246670;XP_005246672;XP_005246673;XP_005246674;XP_005246675;XP_006712604;XP_006712605 NM_001164507;NM_001164508;NM_001271208;NM_004543;XM_005246590;XM_005246591;XM_005246592;XM_005246593;XM_005246594;XM_005246595;XM_005246596;XM_005246597;XM_005246598;XM_005246599;XM_005246600;XM_005246601;XM_005246602;XM_005246603;XM_005246604;XM_005246606;XM_005246608;XM_005246610;XM_005246611;XM_005246612;XM_005246613;XM_005246615;XM_005246616;XM_005246617;XM_005246618;XM_006712541;XM_006712542 ENSP00000380505 P20929 TRUE can 0 0 0 Eukaryotes 0 Cellular processes,Development,Regulation of intracellular processes and metabolism chr2 152359307 152584420 |NEB177D| NP_001258137 0 FALSE 1 36 9967 0.0510 2
4715 NDUFB9 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 9, 22kDa 8q13.3 3264 7704 601445 NP_001265574;NP_001265575;NP_004996 NM_001278645;NM_001278646;NM_005005 ENSP00000276689 Q9Y6M9 TRUE can 0 0 1 Eukaryotes 0 Cell response to stimuli,Cellular metabolism,Cellular processes chr8 125551428 125562130 |B22|CI-B22|LYRM3|UQOR22| NP_004996 1 FALSE 1 33 6588 0.0830 2
4751 NEK2 NIMA-related kinase 2 1q32.3 4953 7745 604043 NP_001191111;NP_001191112;NP_002488;XP_005273204 NM_001204182;NM_001204183;NM_002497;XM_005273147 ENSP00000355966 P51955 TRUE can 0 0 4 Eukaryotes 2 Cell cycle,Cellular metabolism,Cellular processes chr1 211836771 211848821 |HsPK21|NEK2A|NLK1|PPP1R111|RP67| NP_002488 4 FALSE 1 31 20886 0.0540 14
4763 NF1 neurofibromin 1 17q11.2 1203 7765 613113 NP_000258;NP_001035957;NP_001121619;XP_005258040;XP_005258041;XP_006721985;XP_006721986;XP_006721987;XP_006721988;XP_006721989;XP_006721990;XP_006721991 NM_000267;NM_001042492;NM_001128147;XM_005257983;XM_005257984;XM_006721922;XM_006721923;XM_006721924;XM_006721925;XM_006721926;XM_006721927;XM_006721928 ENSP00000351015 P21359 TRUE cgc 0 1 0 Eukaryotes 2 Cell cycle,Cell motility and interactions,Cell response to stimuli,Cellular processes,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Signal transduction chr17 29422328 29701170 |NFNS|VRNF| XP_005258040 0 FALSE 8 27 5176 0.1230 5
4771 NF2 neurofibromin 2 (merlin) 22q12.2 6980 7773 607379 NP_000259;NP_057502;NP_861546;NP_861966;NP_861967;NP_861968;NP_861969;NP_861970;NP_861971 NM_000268;NM_016418;NM_181825;NM_181826;NM_181827;NM_181828;NM_181829;NM_181830;NM_181831;NM_181832;NM_181833;NM_181834;NM_181835 ENSP00000344666 P35240 TRUE cgc 0 1 0 Eukaryotes 4 Cell cycle,Cell motility and interactions,Cell response to stimuli,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction chr22 29999988 30090788 |BANF|SCH| NP_000259 0 FALSE 3 41 10189 0.0900 2
4780 NFE2L2 nuclear factor, erythroid 2-like 2 2q31 2732 7782 600492 NP_001138884;NP_001138885;NP_006155 NM_001145412;NM_001145413;NM_006164 ENSP00000380252 Q16236 TRUE cgc 1 0 0 Metazoans 6 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr2 178095516 178129304 |NA| NP_006155 0 FALSE 10 63 18736 0.1010 1
4781 NFIB nuclear factor I/B 9p24.1 9008 7785 600728 NP_001177666;NP_001177667;NP_001269716;NP_005587;XP_005251524;XP_005251525;XP_005251526;XP_005251527;XP_005251528;XP_006716836;XP_006716837;XP_006716838 NM_001190737;NM_001190738;NM_001282787;NM_005596;XM_005251467;XM_005251468;XM_005251469;XM_005251470;XM_005251471;XM_006716773;XM_006716774;XM_006716775 ENSP00000370340 O00712 TRUE cgc 1 0 0 Metazoans 9 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr9 14088199 14307540 |HMGIC/NFIB|NF-I/B|NF1-B|NFI-B|NFI-RED|NFIB2|NFIB3| XP_005251524 0 FALSE 1 7 1053 0.2380
4791 NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) 10q24 1239 7795 164012 NP_001070962;NP_001248332;NP_001275653;NP_002493;XP_005269917;XP_005269918;XP_006717932 NM_001077494;NM_001261403;NM_001288724;NM_002502;XM_005269860;XM_005269861;XM_006717869 ENSP00000358983 Q00653 TRUE cgc 1 0 0 Last Universal Common Ancestor 2 Cell motility and interactions,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Immune system response,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction chr10 104156004 104162130 |CVID10|H2TF1|LYT-10|LYT10|NF-kB2| NP_001070962 0 FALSE 1 120 18505 0.1440 21
4792 NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 14q13 1235 7797 164008 NP_065390 NM_020529 ENSP00000216797 P25963 TRUE can 0 0 0 Last Universal Common Ancestor 4 Cell cycle,Cell response to stimuli,Cellular processes,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Signal transduction chr14 35871222 35873850 |IKBA|MAD-3|NFKBI| NP_065390 0 FALSE 1 134 72119 0.0960 22
4841 NONO non-POU domain containing, octamer-binding Xq13.1 2098 7871 300084 NP_001138880;NP_001138881;NP_001138882;NP_031389 NM_001145408;NM_001145409;NM_001145410;NM_007363 ENSP00000276079 Q15233 TRUE cgc 1 0 1 Metazoans 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chrX 70510488 70519923 |NMT55|NRB54|P54NRB|PPP1R114| NP_001138880 1 FALSE 1 132 69219 0.1000 11
4849 CNOT3 CCR4-NOT transcription complex, subunit 3 19q13.4 5368 7879 604910 NP_055331;XP_005259013;XP_005259014;XP_005259015;XP_005259016;XP_005277133;XP_005277134;XP_005277135;XP_005277136;XP_005277323;XP_005277324;XP_005277325;XP_005277326;XP_005278336;XP_005278337;XP_005278338;XP_005278339;XP_006725834;XP_006725835;XP_006725836;XP_006725837;XP_006725935;XP_006725936;XP_006725937;XP_006725938;XP_006726023;XP_006726024;XP_006726025;XP_006726026;XP_006726122;XP_006726123;XP_006726124;XP_006726125;XP_006726223;XP_006726224;XP_006726225;XP_006726226;XP_006726260;XP_006726261;XP_006726262;XP_006726263 NM_014516;XM_005258956;XM_005258957;XM_005258958;XM_005258959;XM_005277076;XM_005277077;XM_005277078;XM_005277079;XM_005277266;XM_005277267;XM_005277268;XM_005277269;XM_005278279;XM_005278280;XM_005278281;XM_005278282;XM_006725771;XM_006725772;XM_006725773;XM_006725774;XM_006725872;XM_006725873;XM_006725874;XM_006725875;XM_006725960;XM_006725961;XM_006725962;XM_006725963;XM_006726059;XM_006726060;XM_006726061;XM_006726062;XM_006726160;XM_006726161;XM_006726162;XM_006726163;XM_006726197;XM_006726198;XM_006726199;XM_006726200;XR_243935;XR_243936;XR_254258;XR_254259;XR_254309;XR_254310;XR_254515;XR_254516;XR_430951;XR_430952;XR_430984;XR_430985;XR_431004;XR_431005;XR_431023;XR_431024;XR_431054;XR_431055;XR_431065;XR_431066 ENSP00000221232;ENSP00000458623;ENSP00000458908;ENSP00000459928;ENSP00000469506;ENSP00000469667;ENSP00000469789;ENSP00000470121;ENSP00000472864 O75175 TRUE cgc 1 0 0 Eukaryotes 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr19 54646854 54659142 |LENG2|NOT3|NOT3H| XP_005259013 0 FALSE 1 21 6974 0.1620 1
4851 NOTCH1 notch 1 9q34.3 1827 7881 190198 NP_060087 NM_017617 ENSP00000277541 P46531 TRUE cgc 1 0 0 Last Universal Common Ancestor 13 Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction chr9 139390526 139440238 |AOS5|AOVD1|TAN1|hN1| NP_060087 0 FALSE 7 191 244548 0.0370 38
4853 NOTCH2 notch 2 1p13-p11 2606 7882 600275 NP_001186930;NP_077719;XP_005270958;XP_005270959;XP_006710730 NM_001200001;NM_024408;XM_005270901;XM_005270902;XM_006710667 ENSP00000256646;ENSP00000464488 Q04721 TRUE cgc 1 0 0 Last Universal Common Ancestor 12 Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction chr1 120457932 120612020 |HJCYS|hN2| NP_077719 0 FALSE 4 41 9219 0.0400 10
4854 NOTCH3 notch 3 19p13.2-p13.1 2607 7883 600276 NP_000426;XP_005259981 NM_000435;XM_005259924 ENSP00000263388;ENSP00000364163;ENSP00000403447 Q9UM47 TRUE can 0 0 0 Last Universal Common Ancestor 3 Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction chr19 15271476 15311716 |CADASIL|CASIL|IMF2| NP_000426 0 FALSE 3 51 86115 0.0310 1
4869 NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) 5q35.1 1246 7910 164040 NP_001032827;NP_002511;NP_954654;XP_005265977;XP_006714932 NM_001037738;NM_002520;NM_199185;XM_005265920;XM_006714869 ENSP00000296930 P06748 TRUE cgc 1 0 31 Vertebrates 0 Cell cycle,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction chr5 170814953 170834778 |B23|NPM| NP_001032827 31 FALSE 1 390 595229 0.0670 18
4893 NRAS neuroblastoma RAS viral (v-ras) oncogene homolog 1p13.2 1273 7989 164790 NP_002515 NM_002524 ENSP00000358548 P01111 TRUE cgc 1 0 2 Last Universal Common Ancestor 9 Cell cycle,Cell response to stimuli,Cellular processes,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Signal transduction chr1 115251159 115258781 |ALPS4|CMNS|N-ras|NCMS|NRAS1|NS6| NP_002515 2 FALSE 9 48 17813 0.0360 17
4914 NTRK1 neurotrophic tyrosine kinase, receptor, type 1 1q21-q22 1869 8031 191315 NP_001007793;NP_001012331;NP_002520 NM_001007792;NM_001012331;NM_002529 ENSP00000431418 P04629 TRUE cgc 1 0 0 Eukaryotes 0 Cellular metabolism,Cellular processes,Development,Regulation of intracellular processes and metabolism,Signal transduction chr1 156830727 156851431 |TRKA|Trk-A|p140-TrkA| NP_002520 0 FALSE 4 54 15335 0.1200 13
4915 NTRK2 neurotrophic tyrosine kinase, receptor, type 2 9q22.1 2712 8032 600456 NP_001007098;NP_001018074;NP_001018075;NP_001018076;NP_006171;XP_005252058;XP_005252060;XP_005252061;XP_005252063;XP_005252064;XP_006717183 NM_001007097;NM_001018064;NM_001018065;NM_001018066;NM_006180;XM_005252001;XM_005252003;XM_005252004;XM_005252006;XM_005252007;XM_006717120 ENSP00000277120 Q16620 TRUE can 0 0 0 Eukaryotes 1 Cellular metabolism,Cellular processes,Development,Regulation of intracellular processes and metabolism,Signal transduction chr9 87285664 87636349 |GP145-TrkB|TRKB|trk-B| NP_006171 0 FALSE 1 37 9925 0.1040 1
4916 NTRK3 neurotrophic tyrosine kinase, receptor, type 3 15q25 1870 8033 191316 NP_001007157;NP_001012338;NP_001230030;NP_002521;XP_006720605;XP_006720606;XP_006720607;XP_006720608;XP_006720609;XP_006720610;XP_006720611;XP_006720612;XP_006720613;XP_006720614;XP_006720615 NM_001007156;NM_001012338;NM_001243101;NM_002530;XM_006720542;XM_006720543;XM_006720544;XM_006720545;XM_006720546;XM_006720547;XM_006720548;XM_006720549;XM_006720550;XM_006720551;XM_006720552 ENSP00000354207 Q16288 TRUE cgc 1 0 0 Eukaryotes 18 Cellular metabolism,Cellular processes,Development,Signal transduction chr15 88420169 88799384 |TRKC|gp145(trkC)| NP_001012338 0 FALSE 4 24 6217 0.1270 1
4926 NUMA1 nuclear mitotic apparatus protein 1 11q13 1236 8059 164009 NP_001273490;NP_006176;XP_006718625;XP_006718626;XP_006718627;XP_006718628;XP_006718629;XP_006718630;XP_006718631;XP_006718632;XP_006718633 NM_001286561;NM_006185;NR_104476;XM_006718562;XM_006718563;XM_006718564;XM_006718565;XM_006718566;XM_006718567;XM_006718568;XM_006718569;XM_006718570 ENSP00000377298 Q14980 TRUE cgc 1 0 0 Vertebrates 1 Cell cycle,Cellular processes chr11 71714933 71746989 |NUMA| NP_006176 0 FALSE 1 68 30157 0.1260 5
4928 NUP98 nucleoporin 98kDa 11p15.5 3012 8068 601021 NP_005378;NP_057404;NP_624357;NP_624358;XP_005253007;XP_006718303;XP_006718304;XP_006718305 NM_005387;NM_016320;NM_139131;NM_139132;XM_005252950;XM_006718240;XM_006718241;XM_006718242;XR_428845 ENSP00000316032 P52948 TRUE cgc 1 0 0 Eukaryotes 2 Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription chr11 3697392 3803347 |NUP196|NUP96| XP_005253007 0 FALSE 1 46 12176 0.1520 12
4958 OMD osteomodulin 9q22.31 10128 8134 - NP_005005 NM_005014 ENSP00000364700 Q99983 TRUE cgc 1 0 0 Last Universal Common Ancestor 0 -1 chr9 95177437 95179840 |OSAD|SLRR2C| NP_005005 0 FALSE 1
5018 OXA1L oxidase (cytochrome c) assembly 1-like 14q11.2 3043 8526 601066 NP_005006 NM_005015 ENSP00000285848 Q15070 TRUE can 0 0 0 Last Universal Common Ancestor 3 Cellular metabolism,Cellular processes chr14 23235731 23240764 |OXA1| NP_005006 0 FALSE 1 19 1602 0.1460
5046 PCSK6 proprotein convertase subtilisin/kexin type 6 15q26.3 1329 8569 167405 NP_002561;NP_612192;NP_612193;NP_612194;NP_612195;NP_612196;NP_612197;NP_612198 NM_002570;NM_138319;NM_138320;NM_138321;NM_138322;NM_138323;NM_138324;NM_138325 ENSP00000305056 P29122 TRUE can 0 0 0 Last Universal Common Ancestor 0 Cell cycle,Cellular metabolism,Cellular processes,Development,Regulation of intracellular processes and metabolism,Signal transduction chr15 101853355 102029686 |PACE4|SPC4| NP_612193 0 FALSE 1 5 687 0.0000
5049 PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa) 11q23 3940 8575 602508 NP_001171675;NP_001171676;NP_001171677;NP_002563 NM_001184746;NM_001184747;NM_001184748;NM_002572;NR_110268;NR_110269;NR_110282 ENSP00000435289 P68402 TRUE cgc 1 0 2 Last Universal Common Ancestor 3 Cellular metabolism,Development,Multicellular activities chr11 117023164 117038412 |HEL-S-303| NP_002563 2 FALSE 1 45 10538 0.1110
5063 PAK3 p21 protein (Cdc42/Rac)-activated kinase 3 Xq23 2142 8592 300142 NP_001121638;NP_001121639;NP_001121640;NP_001121644;NP_001121645;NP_002569;XP_005262189;XP_005262190;XP_006724717;XP_006724718;XP_006724719 NM_001128166;NM_001128167;NM_001128168;NM_001128172;NM_001128173;NM_002578;XM_005262132;XM_005262133;XM_006724654;XM_006724655;XM_006724656;XR_244474 ENSP00000244741;ENSP00000353864 O75914 TRUE can 0 0 0 Last Universal Common Ancestor 1 Cellular metabolism,Cellular processes chrX 110366332 110463672 |MRX30|MRX47|OPHN3|PAK3beta|bPAK|hPAK3| NP_001121640 0 FALSE 1 14 269 0.2420 7
5077 PAX3 paired box 3 2q35 9421 8617 606597 NP_000429;NP_001120838;NP_039230;NP_852122;NP_852123;NP_852124;NP_852125;NP_852126;XP_006712622 NM_000438;NM_001127366;NM_013942;NM_181457;NM_181458;NM_181459;NM_181460;NM_181461;XM_006712559 ENSP00000375921 P23760 TRUE cgc 1 0 0 Metazoans 5 Cell cycle,Cell response to stimuli,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription chr2 223065896 223163334 |CDHS|HUP2|WS1| NP_852124 0 FALSE 1 24 10197 0.0760 5
5079 PAX5 paired box 5 9p13 1334 8619 167414 NP_001267476;NP_001267477;NP_001267478;NP_001267479;NP_001267480;NP_001267481;NP_001267482;NP_001267483;NP_001267484;NP_001267485;NP_057953;XP_005251538 NM_001280547;NM_001280548;NM_001280549;NM_001280550;NM_001280551;NM_001280552;NM_001280553;NM_001280554;NM_001280555;NM_001280556;NM_016734;NR_103999;NR_104000;XM_005251481 ENSP00000396259 Q02548 TRUE cgc 1 0 0 Metazoans 0 Cellular metabolism,DNA/RNA metabolism and transcription,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Regulation of transcription chr9 36840560 37034028 |ALL3|BSAP| NP_057953 0 FALSE 2 15 532 0.2000
5081 PAX7 paired box 7 1p36.13 1331 8621 167410 NP_001128726;NP_002575;NP_039236;XP_005245941 NM_001135254;NM_002584;NM_013945;XM_005245884 ENSP00000364524 P23759 TRUE cgc 1 0 0 Metazoans 1 Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription chr1 18958098 19062530 |HUP1|PAX7B|RMS2| NP_002575 0 FALSE 1 12 696 0.1360
5087 PBX1 pre-B-cell leukemia homeobox 1 1q23 8889 8632 176310 NP_001191890;NP_001191892;NP_002576;XP_005245285;XP_005245286;XP_005245287;XP_006711410 NM_001204961;NM_001204963;NM_002585;XM_005245228;XM_005245229;XM_005245230;XM_006711347 ENSP00000405890 P40424 TRUE cgc 1 0 1 Eukaryotes 4 Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription chr1 164529060 164815910 |NA| XP_005245285 1 FALSE 1 34 17087 0.1140 9
5101 PCDH9 protocadherin 9 13q21.32 4661 8661 603581 NP_065136;NP_982354;XP_005266463;XP_005266464;XP_005266465 NM_020403;NM_203487;XM_005266406;XM_005266407;XM_005266408 ENSP00000367096 Q9HC56 TRUE can 0 0 0 Metazoans 1 Cell motility and interactions chr13 66878790 67802572 |NA| NP_982354 0 FALSE 1 4 1004 0.1670
5108 PCM1 pericentriolar material 1 8p22-p21.3 - 8727 600299 NP_006188;XP_005273566;XP_005273569;XP_005273576;XP_005273577;XP_005273578;XP_006716399;XP_006716400;XP_006716401;XP_006716402;XP_006716403;XP_006716404;XP_006716405;XP_006716406;XP_006716407;XP_006716408;XP_006716409;XP_006716410;XP_006716411;XP_006716412;XP_006716413 NM_006197;XM_005273509;XM_005273512;XM_005273519;XM_005273520;XM_005273521;XM_006716336;XM_006716337;XM_006716338;XM_006716339;XM_006716340;XM_006716341;XM_006716342;XM_006716343;XM_006716344;XM_006716345;XM_006716346;XM_006716347;XM_006716348;XM_006716349;XM_006716350;XR_428310 ENSP00000405268 Q15154 TRUE cgc 1 0 0 Opisthokonts 0 Cellular processes,Development chr8 17793120 17883166 |PTC4| XP_005273566 0 FALSE 1 40 14930 0.0860 11
5148 PDE6G phosphodiesterase 6G, cGMP-specific, rod, gamma 17q25 8914 8789 180073 NP_002593;XP_006722005 NM_002602;NR_026872;XM_006721942 - P18545 TRUE can 0 0 0 - 1 Cell response to stimuli,Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism,Signal transduction chr17 79618107 79620335 |PDEG|RP57| NP_002593 0 FALSE 1 10 556 0.2000 2
5155 PDGFB platelet-derived growth factor beta polypeptide 22q13.1 1815 8800 190040 NP_002599;NP_148937 NM_002608;NM_033016 ENSP00000330382 P01127 TRUE cgc 1 0 0 Vertebrates 2 Cell cycle,Cell motility and interactions,Cell response to stimuli,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Immune system response,Multicellular activities,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction chr22 39621731 39639968 |IBGC5|PDGF-2|PDGF2|SIS|SSV|c-sis| NP_002599 0 FALSE 1 24 21645 0.1340 19
5156 PDGFRA platelet-derived growth factor receptor, alpha polypeptide 4q12 1429 8803 173490 NP_006197;XP_005265800;XP_006714102;XP_006714103;XP_006714104 NM_006206;XM_005265743;XM_006714039;XM_006714040;XM_006714041 ENSP00000257290 P16234 TRUE cgc 1 0 0 Eukaryotes 2 Cell cycle,Cell motility and interactions,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction chr4 55124936 55161436 |CD140A|PDGFR-2|PDGFR2|RHEPDGFRA| NP_006197 0 FALSE 3 36 39138 0.1980 21
5159 PDGFRB platelet-derived growth factor receptor, beta polypeptide 5q33.1 1423 8804 173410 NP_002600;XP_005268521 NM_002609;XM_005268464 ENSP00000261799;ENSP00000286301 P09619 TRUE cgc 1 0 0 Eukaryotes 1 Cell cycle,Cell motility and interactions,Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism,Signal transduction chr5 149495329 149515445 |CD140B|IBGC4|IMF1|JTK12|PDGFR|PDGFR-1|PDGFR1| NP_002600 0 FALSE 2 83 46188 0.1380 19
5162 PDHB pyruvate dehydrogenase (lipoamide) beta 3p21.1-p14.2 1530 8808 179060 NP_000916;NP_001166939 NM_000925;NM_001173468;NR_033384 ENSP00000307241 P11177 TRUE can 0 0 0 Last Universal Common Ancestor 1 Cellular metabolism chr3 58413764 58419536 |PDHBD|PDHE1-B|PHE1B| NP_000916 0 FALSE 1 42 10799 0.0880 3
5173 PDYN prodynorphin 20p13 8838 8820 131340 NP_001177821;NP_001177827;NP_001177828;NP_001177829;NP_077722 NM_001190892;NM_001190898;NM_001190899;NM_001190900;NM_024411 ENSP00000217305 P01213 TRUE can 0 0 0 Vertebrates 0 Multicellular activities,Signal transduction chr20 1960972 1963730 |ADCA|PENKB|SCA23| NP_001177821 0 FALSE 1 2 279 0.0000 6
5178 PEG3 paternally expressed 3 19q13.4 3285 8826 601483 NP_001139656;NP_001139657;NP_001139658;NP_001139659;NP_006201 NM_001146184;NM_001146185;NM_001146186;NM_001146187;NM_006210 ENSP00000221722;ENSP00000326581 Q9GZU2 TRUE can 0 0 -1 Eukaryotes 1 Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription - 0 0 |PW1|ZKSCAN22|ZNF904|ZSCAN24| - -1 FALSE 1
5187 PER1 period circadian clock 1 17p13.1 3774 8845 602260 NP_002607;XP_005256746;XP_005256747 NM_002616;XM_005256689;XM_005256690 ENSP00000300658;ENSP00000314420 O15534 TRUE cgc 1 0 0 Eukaryotes 1 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction chr17 8044389 8054024 |PER|RIGUI|hPER| NP_002607 0 FALSE 1 17 3065 0.1470 4
5214 PFKP phosphofructokinase, platelet 10p15.3-p15.2 1384 8878 171840 NP_001229268;NP_002618;XP_005252522;XP_005252523;XP_005252524;XP_006717512 NM_001242339;NM_002627;XM_005252465;XM_005252466;XM_005252467;XM_006717449 ENSP00000370517 Q01813 TRUE can 0 0 0 Last Universal Common Ancestor 4 Cellular metabolism chr10 3109788 3178768 |PFK-C|PFK-P|PFKF| XP_005252522 0 FALSE 1 48 8857 0.1140
5243 ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 7q21.12 1370 40 171050 NP_000918 NM_000927 ENSP00000265724 P08183 TRUE can 0 0 1 Last Universal Common Ancestor 1 -1 chr7 87133562 87229500 |ABC20|CD243|CLCS|GP170|P-GP|PGY1| NP_000918 1 FALSE 2 16 3064 0.0330
5265 SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 14q32.1 2463 8941 107400 NP_000286;NP_001002235;NP_001002236;NP_001121172;NP_001121173;NP_001121174;NP_001121175;NP_001121176;NP_001121177;NP_001121178;NP_001121179 NM_000295;NM_001002235;NM_001002236;NM_001127700;NM_001127701;NM_001127702;NM_001127703;NM_001127704;NM_001127705;NM_001127706;NM_001127707 ENSP00000348068 P01009 TRUE can 0 0 0 Last Universal Common Ancestor 1 Cell response to stimuli,Immune system response,Multicellular activities chr14 94844789 94849574 |A1A|A1AT|AAT|PI1|PRO2275|alpha1AT| NP_000286 0 FALSE 1 35 31458 0.0340 3
5286 PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha 11p15.5-p14 4672 8971 603601 NP_002636;XP_005253034;XP_005253035;XP_005253036;XP_005253037 NM_002645;XM_005252977;XM_005252978;XM_005252979;XM_005252980 ENSP00000265970 O00443 TRUE can 0 0 0 Eukaryotes 6 Cellular metabolism,Cellular processes,Signal transduction chr11 17111288 17191288 |CPK|PI3-K-C2(ALPHA)|PI3-K-C2A| NP_002636 0 FALSE 1 22 1892 0.0690 1
5287 PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta 1q32 4160 8972 602838 NP_002637;XP_005245314;XP_005245315;XP_006711447 NM_002646;XM_005245257;XM_005245258;XM_006711384;XR_241085;XR_241086 ENSP00000356155 O00750 TRUE can 0 0 0 Eukaryotes 3 Cellular metabolism,Cellular processes,Signal transduction chr1 204393983 204438930 |C2-PI3K| NP_002637 0 FALSE 2 16 914 0.3670 1
5288 PIK3C2G phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 gamma 12p12 16416 8973 609001 NP_001275701;NP_001275703;NP_004561;XP_005253450;XP_006719151 NM_001288772;NM_001288774;NM_004570;XM_005253393;XM_006719088 ENSP00000266497 O75747 TRUE can 0 0 0 Eukaryotes 0 Cellular metabolism,Cellular processes,Signal transduction chr12 18435016 18800959 |PI3K-C2-gamma|PI3K-C2GAMMA| NP_001275701 0 FALSE 1
5290 PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 3q26.3 - 8975 171834 NP_006209;XP_006713721 NM_006218;XM_006713658 ENSP00000263967 P42336 TRUE cgc 1 0 0 Eukaryotes 2 Cellular metabolism,Cellular processes,Signal transduction chr3 178916614 178952149 |CLOVE|CWS5|MCMTC|p110-alpha| NP_006209 0 FALSE 17 74 28392 0.0660 40
5291 PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta 3q22.3 - 8976 602925 NP_001242974;NP_006210;XP_005247587;XP_005247588;XP_005247589;XP_006713722 NM_001256045;NM_006219;XM_005247530;XM_005247531;XM_005247532;XM_006713659 ENSP00000289153 P42338 TRUE can 0 0 0 Eukaryotes 3 Cell motility and interactions,Cellular metabolism,Cellular processes,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Signal transduction chr3 138374234 138478185 |P110BETA|PI3KBETA|PIK3C1| NP_006210 0 FALSE 1 22 3829 0.2120 12
5292 PIM1 Pim-1 proto-oncogene, serine/threonine kinase 6p21.2 1292 8986 164960 NP_001230115;NP_002639 NM_001243186;NM_002648 ENSP00000353826;ENSP00000362608 P11309 TRUE cgc 1 0 0 Last Universal Common Ancestor 9 Cell cycle,Cellular metabolism,Cellular processes,Development,Regulation of intracellular processes and metabolism chr6 37138082 37141864 |PIM| NP_001230115 0 FALSE 1 43 15539 0.0840 1
5293 PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta 1p36.2 - 8977 602839 NP_005017;XP_005263530;XP_006710749;XP_006710750;XP_006710751;XP_006710752;XP_006710753 NM_005026;XM_005263473;XM_006710686;XM_006710687;XM_006710688;XM_006710689;XM_006710690 ENSP00000366513 O00329 TRUE can 0 0 0 Eukaryotes 1 Cellular metabolism,Cellular processes,Signal transduction chr1 9770514 9787101 |APDS|IMD14|P110DELTA|p110D| NP_005017 0 FALSE 1 18 3808 0.0980 6
5294 PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma 7q22.3 3135 8978 601232 NP_001269355;NP_001269356;NP_002640;XP_005250500;XP_006716090 NM_001282426;NM_001282427;NM_002649;XM_005250443;XM_006716027 ENSP00000352121 P48736 TRUE can 0 0 0 Eukaryotes 2 Cell cycle,Cellular metabolism,Cellular processes,Development,Regulation of intracellular processes and metabolism,Signal transduction chr7 106508007 106545829 |PI3CG|PI3Kgamma|PIK3|p110gamma|p120-PI3K| NP_001269355 0 FALSE 2 33 37970 0.0530 1
5295 PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 5q13.1 1381 8979 171833 NP_001229395;NP_852556;NP_852664;NP_852665;XP_005248599 NM_001242466;NM_181504;NM_181523;NM_181524;XM_005248542 ENSP00000274335 P27986 TRUE cgc 0 1 0 Metazoans 6 Cellular metabolism,Cellular processes,Signal transduction chr5 67522504 67593426 |AGM7|GRB1|IMD36|p85-ALPHA| NP_852664 0 FALSE 7 284 393774 0.0530 82
5297 PI4KA phosphatidylinositol 4-kinase, catalytic, alpha 22q11.21 8972 8983 600286 NP_002641;NP_477352;XP_005261691;XP_005261692 NM_002650;NM_058004;XM_005261634;XM_005261635 ENSP00000458238 Q4LE69 TRUE can 0 0 0 Eukaryotes 0 Cellular metabolism,Cellular processes,Multicellular activities,Signal transduction chr22 21062338 21213013 |PI4K-ALPHA|PIK4CA|pi4K230| NP_477352 0 FALSE 1 14 1872 0.0330 2
5314 PKHD1 polycystic kidney and hepatic disease 1 (autosomal recessive) 6p12.2 5987 9016 606702 NP_619639;NP_733842 NM_138694;NM_170724 ENSP00000360158 P08F94 TRUE can 0 0 0 Eukaryotes 0 Cell motility and interactions,Regulation of intracellular processes and metabolism chr6 51483882 51949731 |ARPKD|FCYT|TIGM1| NP_619639 0 FALSE 3 2 42 0.0000 1
5324 PLAG1 pleiomorphic adenoma gene 1 8q12 4321 9045 603026 NP_001108106;NP_001108107;NP_002646;XP_005251317 NM_001114634;NM_001114635;NM_002655;XM_005251260 ENSP00000325546 Q6DJT9 TRUE cgc 1 0 0 Eukaryotes 23 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr8 57078805 57080828 |SGPA|ZNF912| NP_001108106 0 FALSE 1 6 212 0.3330 1
5332 PLCB4 phospholipase C, beta 4 20p12 2885 9059 600810 NP_000924;NP_001166117;NP_877949;XP_005260781;XP_005260785;XP_006723631;XP_006723632;XP_006723633;XP_006723634;XP_006723635 NM_000933;NM_001172646;NM_182797;XM_005260724;XM_005260728;XM_006723568;XM_006723569;XM_006723570;XM_006723571;XM_006723572 ENSP00000334105 Q15147 TRUE can 0 0 0 Opisthokonts 4 Cellular metabolism,Signal transduction chr20 9288462 9459653 |ARCND2| XP_005260781 0 FALSE 1 2 22 0.0000 1
5335 PLCG1 phospholipase C, gamma 1 20q12-q13.1 1398 9065 172420 NP_002651;NP_877963;XP_005260495 NM_002660;NM_182811;XM_005260438;XR_244143 ENSP00000244007 P19174 TRUE can 0 0 0 Eukaryotes 1 Cellular metabolism,Development,Signal transduction chr20 39766282 39802952 |NCKAP3|PLC-II|PLC1|PLC148|PLCgamma1| XP_005260495 0 FALSE 2 201 157484 0.0650 58
5336 PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific) 16q24.1 - 9066 600220 NP_002652 NM_002661 ENSP00000352336 P16885 TRUE can 0 0 0 Eukaryotes 1 Cellular metabolism,Signal transduction chr16 81819595 81991600 |APLAID|FCAS3|PLC-IV|PLC-gamma-2| NP_002652 0 FALSE 1 64 19275 0.1700 26
5362 PLXNA2 plexin A2 1q32.2 3033 9100 601054 NP_079455;XP_005273221;XP_005273222;XP_006711450 NM_025179;XM_005273164;XM_005273165;XM_006711387 ENSP00000356000 O75051 TRUE can 0 0 0 Last Universal Common Ancestor 4 Signal transduction chr1 208200591 208391312 |OCT|PLXN2| XP_005273221 0 FALSE 1 8 14930 0.0000 10
5371 PML promyelocytic leukemia 15q22 23 9113 102578 NP_002666;NP_150241;NP_150242;NP_150243;NP_150247;NP_150249;NP_150250;NP_150252;NP_150253 NM_002675;NM_033238;NM_033239;NM_033240;NM_033244;NM_033246;NM_033247;NM_033249;NM_033250 ENSP00000268058 P29590 TRUE cgc 1 0 0 Eukaryotes 1 Cell cycle,Cell response to stimuli,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction chr15 74287154 74337346 |MYL|PP8675|RNF71|TRIM19| NP_150241 0 FALSE 1 185 127999 0.0860 11
5378 PMS1 PMS1 postmeiotic segregation increased 1 (S. cerevisiae) 2q31.1 2597 9121 600258 NP_000525;NP_001121615;NP_001121616;NP_001276337;NP_001276338;XP_005246704;XP_005246706;XP_006712659 NM_000534;NM_001128143;NM_001128144;NM_001289408;NM_001289409;NR_110332;XM_005246647;XM_005246649;XM_006712596 ENSP00000406490 P54277 TRUE cgc 0 1 0 Last Universal Common Ancestor 2 Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr2 190656536 190742159 |HNPCC3|PMSL1|hPMS1| NP_000525 0 FALSE 2 48 15308 0.0760 3
5387 PMS2P3 postmeiotic segregation increased 2 pseudogene 3 7q11.23 - 9128 - - NM_001003686;NM_005395;NR_028059 ENSP00000265849 NA TRUE can 0 0 -1 Last Universal Common Ancestor 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription - 0 0 |PMS2L3|PMS2L9|PMS5|PMSR3| - -1 FALSE 1
5395 PMS2 PMS2 postmeiotic segregation increased 2 (S. cerevisiae) 7p22.2 2598 9122 600259 NP_000526;XP_006715805;XP_006715806;XP_006715807 NM_000535;NR_003085;XM_006715742;XM_006715743;XM_006715744 ENSP00000265849 P54278 TRUE cgc 0 1 0 Last Universal Common Ancestor 0 Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism chr7 6013033 6045667 |HNPCC4|PMSL2| NP_000526 0 FALSE 1 53 15510 0.0940 16
5396 PRRX1 paired related homeobox 1 1q24 1337 9142 167420 NP_008833;NP_073207;XP_006711451 NM_006902;NM_022716;XM_006711388 ENSP00000239461 P54821 TRUE cgc 1 0 0 Eukaryotes 3 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr1 170633360 170705324 |AGOTC|PHOX1|PMX1|PRX-1| NP_073207 0 FALSE 1 5 50 0.2000
5411 PNN pinin, desmosome associated protein 14q21.1 4401 9162 603154 NP_002678 NM_002687 ENSP00000216832 Q9H307 TRUE can 0 0 0 Eukaryotes 7 Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr14 39644484 39651064 |DRSP|SDK3|memA| NP_002678 0 FALSE 1 44 14532 0.1800 1
5413 SEPT5 septin 5 22q11.21 4100 9164 602724 NP_001009939;NP_002679 NM_001009939;NM_002688 ENSP00000391311 Q99719 TRUE cgc 1 0 0 Eukaryotes 0 Cellular processes,Multicellular activities,Regulation of intracellular processes and metabolism,Signal transduction chr22 19702112 19710004 |CDCREL|CDCREL-1|CDCREL1|HCDCREL-1|PNUTL1| NP_002679 0 FALSE 1 20 5890 0.1000 1
5426 POLE polymerase (DNA directed), epsilon, catalytic subunit 12q24.3 7177 9177 174762 NP_006222 NM_006231 ENSP00000322570 Q07864 TRUE can 0 0 0 Last Universal Common Ancestor 1 Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription chr12 133201286 133257867 |CRCS12|FILS|POLE1| NP_006222 0 FALSE 1 19 2777 0.1750 8
5450 POU2AF1 POU class 2 associating factor 1 11q23.1 3126 9211 601206 NP_006226;XP_005271650;XP_005271651;XP_006718922;XP_006718923 NM_006235;XM_005271593;XM_005271594;XM_006718859;XM_006718860 ENSP00000376786 Q16633 TRUE cgc 1 0 0 Vertebrates 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr11 111224989 111234060 |BOB1|OBF-1|OBF1|OCAB| XP_005271650 0 FALSE 1 16 6637 0.0080 4
5452 POU2F2 POU class 2 homeobox 2 19q13.2 1251 9213 164176 NP_001193954;NP_001193955;NP_001234923;NP_002689;XP_005259066;XP_005259067;XP_005259068;XP_005259069 NM_001207025;NM_001207026;NM_001247994;NM_002698;XM_005259009;XM_005259010;XM_005259011;XM_005259012 ENSP00000431603 P09086 TRUE can 0 0 0 Metazoans 1 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr19 42595412 42626732 |OTF2|Oct-2| XP_005259066 0 FALSE 1 14 353 0.2420 2
5460 POU5F1 POU class 5 homeobox 1 6p21.31 1252 9221 164177 NP_001167002;NP_001272915;NP_001272916;NP_002692;NP_976034 NM_001173531;NM_001285986;NM_001285987;NM_002701;NM_203289 ENSP00000259915;ENSP00000373016;ENSP00000375557;ENSP00000388842;ENSP00000391681;ENSP00000392877;ENSP00000400047;ENSP00000405041 Q01860 TRUE cgc 1 0 3 Vertebrates 1 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr6 31132381 31138397 |OCT4|OTF-3|OTF3|OTF4|Oct-3|Oct-4| NP_002692 3 FALSE 1 64 34912 0.0550 18
5468 PPARG peroxisome proliferator-activated receptor gamma 3p25 3288 9236 601487 NP_005028;NP_056953;NP_619725;NP_619726;XP_006713271 NM_005037;NM_015869;NM_138711;NM_138712;XM_006713208 ENSP00000287820 P37231 TRUE cgc 1 0 0 Eukaryotes 8 Cell cycle,Cell response to stimuli,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Immune system response,Multicellular activities,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction chr3 12393092 12475641 |CIMT1|NR1C3|PPARG1|PPARG2|PPARgamma| NP_056953 0 FALSE 1 152 122162 0.0780 6
5469 MED1 mediator complex subunit 1 17q12 5055 9234 604311 NP_004765;XP_005257522;XP_006722020 NM_004774;XM_005257465;XM_006721957 ENSP00000249910;ENSP00000300651 Q15648 TRUE can 0 0 0 Eukaryotes 2 Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction chr17 37563731 37604158 |CRSP1|CRSP200|DRIP205|DRIP230|PPARBP|PPARGBP|RB18A|TRAP220|TRIP2| NP_004765 0 FALSE 1 96 29710 0.2030 44
5506 PPP1R3A protein phosphatase 1, regulatory subunit 3A 7q31.1 2950 9291 600917 NP_002702;XP_005250530 NM_002711;XM_005250473 ENSP00000284601 Q16821 TRUE can 0 0 0 Opisthokonts 1 Cellular metabolism chr7 113517781 113559051 |GM|PP1G|PPP1R3| NP_002702 0 FALSE 2 3 234 0.0000
5518 PPP2R1A protein phosphatase 2, regulatory subunit A, alpha 19q13.41 - 9302 605983 NP_055040 NM_014225;NR_033500 ENSP00000324804 P30153 TRUE cgc 1 0 1 Eukaryotes 2 Cell cycle,Cell motility and interactions,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction chr19 52693350 52729060 |PP2A-Aalpha|PP2AAALPHA|PR65A| NP_055040 1 FALSE 4 180 168164 0.0660 26
5525 PPP2R5A protein phosphatase 2, regulatory subunit B, alpha 1q32.2-q32.3 3384 9309 601643 NP_001186685;NP_006234 NM_001199756;NM_006243 ENSP00000261461 Q15172 TRUE can 0 0 0 Eukaryotes 3 Signal transduction chr1 212459453 212534109 |B56A|PR61A| NP_006234 0 FALSE 1 31 3918 0.1330 2
5537 PPP6C protein phosphatase 6, catalytic subunit 9q33.3 2141 9323 612725 NP_001116827;NP_001116841;NP_002712;XP_006717238 NM_001123355;NM_001123369;NM_002721;XM_006717175 ENSP00000392147 O00743 TRUE can 0 0 0 Eukaryotes 4 Cell cycle,Cellular metabolism,Cellular processes chr9 127911955 127951997 |PP6|PP6C| NP_001116827 0 FALSE 1 37 6181 0.1520 7
5545 PRB4 proline-rich protein BstNI subfamily 4 12p13.2 1624 9340 180990 NP_001248328;NP_002714 NM_001261399;NM_002723 - P10163 TRUE can 0 0 7 - 0 -1 chr12 11461176 11463332 |Po| NP_002714 7 FALSE 1 1 0 0.0000
5546 PRCC papillary renal cell carcinoma (translocation-associated) 1q21.1 1562 9343 179755 NP_005964;XP_005245370;XP_005245371 NM_005973;NM_199416;XM_005245313;XM_005245314 ENSP00000271526 Q92733 TRUE cgc 1 0 0 Eukaryotes 0 -1 chr1 156737564 156770249 |RCCP1|TPRC| XP_005245370 0 FALSE 1 11 333 0.1450
5551 PRF1 perforin 1 (pore forming protein) 10q22 1362 9360 170280 NP_001076585;NP_005032 NM_001083116;NM_005041 ENSP00000225655;ENSP00000316746 P14222 TRUE cgc 0 1 0 Metazoans 0 Cell cycle,Cell response to stimuli,Cellular processes,Other chr10 72357812 72360658 |FLH2|HPLH2|PFP| NP_001076585 0 FALSE 1 7 592 0.0480
5565 PRKAB2 protein kinase, AMP-activated, beta 2 non-catalytic subunit 1q21.1 4117 9379 602741 NP_005390 NM_005399;NR_103870;NR_103871 ENSP00000254101;ENSP00000463518 O43741 TRUE can 0 0 0 Eukaryotes 6 Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism,Signal transduction chr1 146631147 146643723 |NA| NP_005390 0 FALSE 1 82 51830 0.0350 10
5566 PRKACA protein kinase, cAMP-dependent, catalytic, alpha 19p13.1 3382 9380 601639 NP_002721;NP_997401;XP_005260041 NM_002730;NM_207518;XM_005259984 ENSP00000309591;ENSP00000408695 P17612 TRUE can 0 0 2 Last Universal Common Ancestor 1 Cellular metabolism,Cellular processes,Signal transduction chr19 14203927 14218796 |PKACA| XP_005260041 2 FALSE 1 238 425150 0.0210 18
5573 PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha 17q24.2 1786 9388 188830 NP_001263218;NP_001263219;NP_001265362;NP_002725;NP_997636;NP_997637 NM_001276289;NM_001276290;NM_001278433;NM_002734;NM_212471;NM_212472 ENSP00000351410;ENSP00000353415 P10644 TRUE cgc 1 1 2 Last Universal Common Ancestor 5 Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction chr17 66511541 66526587 |ACRDYS1|ADOHR|CNC1|PPNAD1|TSE1| NP_001263218 2 FALSE 2 99 134668 0.0500 2
5579 PRKCB protein kinase C, beta 16p11.2 1499 9395 176970 NP_002729;NP_997700 NM_002738;NM_212535 ENSP00000305355 P05771 TRUE can 0 0 1 Last Universal Common Ancestor 3 Cellular metabolism,Cellular processes,Signal transduction chr16 23847497 24226134 |PKC-beta|PKCB|PRKCB1|PRKCB2| NP_002729 1 FALSE 1 106 75459 0.0540
5582 PRKCG protein kinase C, gamma 19q13.4 1502 9402 176980 NP_002730 NM_002739 ENSP00000263431 P05129 TRUE can 0 0 0 Eukaryotes 1 Cell response to stimuli,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction chr19 54385749 54410146 |PKC-gamma|PKCC|PKCG|SCA14| NP_002730 0 FALSE 1 63 32706 0.0370
5587 PRKD1 protein kinase D1 14q11 5668 9407 605435 NP_002733;XP_005267916 NM_002742;XM_005267859 ENSP00000333568 Q15139 TRUE can 0 0 0 Eukaryotes 1 Cellular metabolism,Cellular processes,Signal transduction chr14 30046447 30396718 |PKC-MU|PKCM|PKD|PRKCM| XP_005267916 0 FALSE 1 35 3503 0.1970
5594 MAPK1 mitogen-activated protein kinase 1 22q11.21 1496 6871 176948 NP_002736;NP_620407 NM_002745;NM_138957 ENSP00000215832 P28482 TRUE can 0 0 1 Eukaryotes 5 Cell cycle,Cell motility and interactions,Cell response to stimuli,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Signal transduction chr22 22123496 22221730 |ERK-2|ERK2|ERT1|MAPK2|P42MAPK|PRKM1|PRKM2|p41|p41mapk|p42-MAPK| NP_002736 1 FALSE 2 276 293528 0.0440 28
5598 MAPK7 mitogen-activated protein kinase 7 17p11.2 3952 6880 602521 NP_002740;NP_620601;NP_620602;NP_620603;XP_005256776;XP_006721620;XP_006721621;XP_006721622;XP_006721623 NM_002749;NM_139032;NM_139033;NM_139034;XM_005256719;XM_006721557;XM_006721558;XM_006721559;XM_006721560 ENSP00000311005 Q13164 TRUE can 0 0 0 Eukaryotes 1 Cellular metabolism,Cellular processes,Signal transduction chr17 19282214 19286541 |BMK1|ERK5|PRKM7| NP_002740 0 FALSE 1 59 35346 0.1090
5604 MAP2K1 mitogen-activated protein kinase kinase 1 15q22.1-q22.33 - 6840 176872 NP_002746;XP_005254598;XP_006720671 NM_002755;XM_005254541;XM_006720608 ENSP00000302486 Q02750 TRUE cgc 1 0 3 Last Universal Common Ancestor 9 Cell cycle,Cell motility and interactions,Cell response to stimuli,Cellular metabolism,Cellular processes,Development,Signal transduction chr15 66679686 66782950 |CFC3|MAPKK1|MEK1|MKK1|PRKMK1| NP_002746 3 FALSE 2 86 36529 0.0940 23
5605 MAP2K2 mitogen-activated protein kinase kinase 2 19p13.3 3164 6842 601263 NP_109587;XP_006722862 NM_030662;XM_006722799 ENSP00000262948 P36507 TRUE cgc 1 0 2 Last Universal Common Ancestor 4 Cellular metabolism,Cellular processes,Signal transduction chr19 4090599 4123872 |CFC4|MAPKK2|MEK2|MKK2|PRKMK2| NP_109587 2 FALSE 2 29 5120 0.1430 16
5606 MAP2K3 mitogen-activated protein kinase kinase 3 17q11.2 3816 6843 602315 NP_002747;NP_659731;XP_005256778;XP_005256779;XP_005256780 NM_002756;NM_145109;NM_145110;XM_005256721;XM_005256722;XM_005256723 ENSP00000345083 P46734 TRUE can 0 0 1 Eukaryotes 5 Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction chr17 21188233 21217539 |MAPKK3|MEK3|MKK3|PRKMK3|SAPKK-2|SAPKK2| NP_659731 1 FALSE 1 28 5411 0.1160
5613 PRKX protein kinase, X-linked Xp22.3 2097 9441 300083 NP_005035;XP_005274617;XP_005274618 NM_005044;XM_005274560;XM_005274561 ENSP00000262848 P51817 TRUE can 0 0 2 Last Universal Common Ancestor 1 Cellular metabolism,Cellular processes chrX 3530244 3631294 |PKX1| NP_005035 2 FALSE 1 9 405 0.0830
5618 PRLR prolactin receptor 5p13.2 1457 9446 176761 NP_000940;NP_001191243;NP_001191244;NP_001191245;NP_001191246;NP_001191247;XP_006714547 NM_000949;NM_001204314;NM_001204315;NM_001204316;NM_001204317;NM_001204318;NR_037910;XM_006714484 ENSP00000371432 P16471 TRUE can 0 0 0 Vertebrates 2 Cell cycle,Cellular metabolism,Cellular processes,Development,Immune system response,Multicellular activities,Regulation of intracellular processes and metabolism,Signal transduction chr5 35065194 35089722 |HPRL|MFAB|hPRLrI| NP_000940 0 FALSE 1 21 3539 0.0810 9
5649 RELN reelin 7q22 2742 9957 600514 NP_005036;NP_774959 NM_005045;NM_173054 ENSP00000392423 P78509 TRUE can 0 0 0 Opisthokonts 4 Cell cycle,Cell motility and interactions,Cell response to stimuli,Cellular metabolism,Cellular processes,Development,Regulation of intracellular processes and metabolism,Signal transduction chr7 103113262 103629803 |PRO1598|RL| NP_005036 0 FALSE 2 5 446 0.2000
5727 PTCH1 patched 1 9q22.3 3200 9585 601309 NP_000255;NP_001077071;NP_001077072;NP_001077073;NP_001077074;NP_001077075;NP_001077076;XP_005252159 NM_000264;NM_001083602;NM_001083603;NM_001083604;NM_001083605;NM_001083606;NM_001083607;XM_005252102;XR_242599 ENSP00000332353 Q13635 TRUE cgc 0 1 0 Eukaryotes 0 Cell cycle,Cellular metabolism,Cellular processes,Development,Regulation of intracellular processes and metabolism,Signal transduction chr9 98209197 98270643 |BCNS|HPE7|NBCCS|PTC1|PTCH|PTCH11| NP_000255 0 FALSE 5 19 22810 0.0470 7
5728 PTEN phosphatase and tensin homolog 10q23.3 - 9588 601728 NP_000305;XP_006717989;XP_006717990 NM_000314;XM_006717926;XM_006717927 ENSP00000361021 P60484 TRUE cgc 0 1 1 Last Universal Common Ancestor 22 Cell cycle,Cell motility and interactions,Cellular metabolism,Cellular processes,Development,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction chr10 89624227 89725226 |BZS|CWS1|DEC|GLM2|MHAM|MMAC1|PTEN1| NP_000305 1 FALSE 16 101 100268 0.0470 1
5737 PTGFR prostaglandin F receptor (FP) 1p31.1 8988 9600 600563 NP_000950;NP_001034674;XP_006710844 NM_000959;NM_001039585;XM_006710781;XR_426624 ENSP00000359793 P43088 TRUE can 0 0 0 Vertebrates 1 Signal transduction chr1 78958429 79002369 |NA| NP_000950 0 FALSE 1 4 40 0.3330 2
5764 PTN pleiotrophin 7q33 1199 9630 162095 NP_002816;XP_005250572;XP_005250573 NM_002825;XM_005250515;XM_005250516 ENSP00000341170 P21246 TRUE can 0 0 0 Vertebrates 0 Cell cycle,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Signal transduction chr7 136935978 136939720 |HBGF8|HBNF|NEGF1| NP_002816 0 FALSE 1 95 95388 0.0160
5770 PTPN1 protein tyrosine phosphatase, non-receptor type 1 20q13.1-q13.2 1477 9642 176885 NP_001265547;NP_002818 NM_001278618;NM_002827 ENSP00000360683 P18031 TRUE can 0 0 0 Last Universal Common Ancestor 7 Cellular metabolism,Cellular processes,Signal transduction chr20 49127065 49197997 |PTP1B| NP_002818 0 FALSE 1 78 33040 0.0650 3
5781 PTPN11 protein tyrosine phosphatase, non-receptor type 11 12q24 1470 9644 176876 NP_002825;NP_542168;XP_006719589;XP_006719590 NM_002834;NM_080601;XM_006719526;XM_006719527 ENSP00000340944 Q06124 TRUE cgc 1 0 5 Last Universal Common Ancestor 7 Cell response to stimuli,Cellular metabolism,Cellular processes,Signal transduction chr12 112884078 112942565 |BPTP3|NS1|PTP-1D|PTP2C|SH-PTP2|SH-PTP3|SHP2| NP_002825 5 FALSE 2 150 183432 0.0890 55
5782 PTPN12 protein tyrosine phosphatase, non-receptor type 12 7q11.23 2513 9645 600079 NP_001124480;NP_001124481;NP_002826;XP_005250575;XP_006716136;XP_006716137 NM_001131008;NM_001131009;NM_002835;XM_005250518;XM_006716073;XM_006716074 ENSP00000248594 Q05209 TRUE can 0 0 0 Last Universal Common Ancestor 7 Cellular metabolism,Cellular processes chr7 77166864 77268594 |PTP-PEST|PTPG1| NP_002826 0 FALSE 1 61 45367 0.0840 1
5784 PTPN14 protein tyrosine phosphatase, non-receptor type 14 1q32.2 4402 9647 603155 NP_005392 NM_005401;XR_247032 ENSP00000355923 Q15678 TRUE can 0 0 0 Last Universal Common Ancestor 2 Cellular metabolism,Cellular processes chr1 214531268 214638146 |PEZ|PTP36| NP_005392 0 FALSE 1 36 4581 0.1760
5787 PTPRB protein tyrosine phosphatase, receptor type, B 12q15-q21 1474 9665 176882 NP_001103224;NP_001193900;NP_001193901;NP_002828;XP_006719591;XP_006719592;XP_006719593 NM_001109754;NM_001206971;NM_001206972;NM_002837;XM_006719528;XM_006719529;XM_006719530;XR_245948;XR_245949 ENSP00000334928 P23467 TRUE can 0 0 0 Last Universal Common Ancestor 3 Cellular metabolism,Cellular processes chr12 70918252 71031175 |HPTP-BETA|HPTPB|PTPB|R-PTP-BETA|VEPTP| NP_001103224 0 FALSE 1 11 469 0.0360 1
5788 PTPRC protein tyrosine phosphatase, receptor type, C 1q31-q32 1050 9666 151460 NP_001254727;NP_002829;NP_563578;XP_006711535;XP_006711536;XP_006711537;XP_006711538 NM_001267798;NM_002838;NM_080921;NM_080922;NR_052021;XM_006711472;XM_006711473;XM_006711474;XM_006711475 ENSP00000356346;ENSP00000458322 P08575 TRUE cgc 0 0 0 Last Universal Common Ancestor 0 Cell cycle,Cell response to stimuli,Cellular metabolism,Cellular processes,Development,Immune system response,Regulation of intracellular processes and metabolism,Signal transduction chr1 198608399 198725307 |B220|CD45|CD45R|L-CA|LY5|T200| NP_002829 0 FALSE 2 50 16674 0.1000 2
5789 PTPRD protein tyrosine phosphatase, receptor type, D 9p23-p24.3 3358 9668 601598 NP_001035802;NP_001164496;NP_002830;NP_569075;NP_569076;NP_569077;XP_006716876;XP_006716877;XP_006716878;XP_006716879;XP_006716880;XP_006716881;XP_006716882;XP_006716883;XP_006716884;XP_006716885;XP_006716886;XP_006716887;XP_006716888;XP_006716889;XP_006716890;XP_006716891;XP_006716892;XP_006716893;XP_006716894;XP_006716895;XP_006716896;XP_006716897;XP_006716898;XP_006716899;XP_006716900;XP_006716901;XP_006716902 NM_001040712;NM_001171025;NM_002839;NM_130391;NM_130392;NM_130393;XM_006716813;XM_006716814;XM_006716815;XM_006716816;XM_006716817;XM_006716818;XM_006716819;XM_006716820;XM_006716821;XM_006716822;XM_006716823;XM_006716824;XM_006716825;XM_006716826;XM_006716827;XM_006716828;XM_006716829;XM_006716830;XM_006716831;XM_006716832;XM_006716833;XM_006716834;XM_006716835;XM_006716836;XM_006716837;XM_006716838;XM_006716839 ENSP00000348812 P23468 TRUE can 0 0 0 Last Universal Common Ancestor 7 Cellular metabolism,Cellular processes,Signal transduction chr9 8317877 8733843 |HPTP|HPTPD|HPTPDELTA|PTPD|RPTPDELTA| NP_002830 0 FALSE 3 9 417 0.3330
5796 PTPRK protein tyrosine phosphatase, receptor type, K 6q22.2-q22.3 3968 9674 602545 NP_001129120;NP_002835;XP_005267139;XP_005267142;XP_005267143;XP_006715598;XP_006715599;XP_006715600;XP_006715601;XP_006715602;XP_006715603;XP_006715604;XP_006725082;XP_006725083;XP_006725084;XP_006725085;XP_006725086;XP_006725087;XP_006725088;XP_006725089;XP_006725090 NM_001135648;NM_002844;XM_005267082;XM_005267085;XM_005267086;XM_006715535;XM_006715536;XM_006715537;XM_006715538;XM_006715539;XM_006715540;XM_006715541;XM_006725019;XM_006725020;XM_006725021;XM_006725022;XM_006725023;XM_006725024;XM_006725025;XM_006725026;XM_006725027 ENSP00000357196 Q15262 TRUE can 0 0 0 Last Universal Common Ancestor 5 Cellular metabolism,Cellular processes chr6 128291375 128841503 |R-PTP-kappa| XP_005267139 0 FALSE 1 11 378 0.0910
5800 PTPRO protein tyrosine phosphatase, receptor type, O 12p13.3-p13.2|12p13-p12 2784 9678 600579 NP_002839;NP_109592;NP_109593;NP_109594;NP_109595;NP_109596 NM_002848;NM_030667;NM_030668;NM_030669;NM_030670;NM_030671 ENSP00000334941 Q16827 TRUE can 0 0 0 Last Universal Common Ancestor 2 Cellular metabolism,Cellular processes chr12 15475661 15747972 |GLEPP1|NPHS6|PTP-OC|PTP-U2|PTPROT|R-PTP-O| NP_109592 0 FALSE 1 13 3252 0.1790
5879 RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 7p22 3627 9801 602048 NP_008839;NP_061485 NM_006908;NM_018890;NM_198829 ENSP00000304283;ENSP00000348461 P63000 TRUE cgc 1 0 17 Eukaryotes 5 Cellular metabolism,Cellular processes,Development,Immune system response,Multicellular activities,Regulation of intracellular processes and metabolism,Signal transduction chr4 46725850 46726425 |Rac-1|TC-25|p21-Rac1| NP_008839 9 FALSE 1 196 224541 0.0290 45
5885 RAD21 RAD21 homolog (S. pombe) 8q24 5924 9811 606462 NP_006256 NM_006265 ENSP00000297338 O60216 TRUE cgc 0 0 1 Eukaryotes 2 Cell cycle,DNA/RNA metabolism and transcription chr8 117859742 117878968 |CDLS4|HR21|HRAD21|MCD1|NXP1|hHR21| NP_006256 1 FALSE 2 222 278883 0.0460 33
5890 RAD51B RAD51 paralog B 14q23-q24.2 4255 9822 602948 NP_002868;NP_598193;NP_598194;XP_005268018;XP_005268019;XP_005268020 NM_002877;NM_133509;NM_133510;XM_005267961;XM_005267962;XM_005267963 ENSP00000419471 O15315 TRUE cgc 1 0 0 Last Universal Common Ancestor 0 Cell cycle,DNA/RNA metabolism and transcription chr14 68290261 68934966 |R51H2|RAD51L1|REC2| NP_598193 0 FALSE 1 11 802 0.2360 9
5894 RAF1 Raf-1 proto-oncogene, serine/threonine kinase 3p25 1265 9829 164760 NP_002871;XP_005265412;XP_005265414;XP_005265415;XP_005265416;XP_005265417 NM_002880;XM_005265355;XM_005265357;XM_005265358;XM_005265359;XM_005265360 ENSP00000251849 P04049 TRUE cgc 1 0 0 Eukaryotes 5 Cell cycle,Cellular metabolism,Cellular processes,Signal transduction chr3 12626016 12660220 |CMD1NN|CRAF|NS5|Raf-1|c-Raf| NP_002871 0 FALSE 2 176 165473 0.0690 35
5897 RAG2 recombination activating gene 2 11p13 8913 9832 179616 NP_000527;NP_001230714;NP_001230715 NM_000536;NM_001243785;NM_001243786;NR_033666 ENSP00000308620 P55895 TRUE can 0 0 0 Vertebrates 0 Cellular metabolism,DNA/RNA metabolism and transcription,Development,Immune system response chr11 36614138 36615718 |RAG-2| NP_000527 0 FALSE 1 6 13 0.4000 1
5900 RALGDS ral guanine nucleotide dissociation stimulator 9q34.3 3371 9842 601619 NP_001035827;NP_001258703;NP_001258704;NP_001258705;NP_006257 NM_001042368;NM_001271774;NM_001271775;NM_001271776;NM_006266 ENSP00000361120 Q12967 TRUE cgc 1 0 0 Metazoans 1 Signal transduction chr9 135973977 135996541 |RGDS|RGF|RalGEF| NP_006257 0 FALSE 1 28 2992 0.1080 1
5910 RAP1GDS1 RAP1, GTP-GDP dissociation stimulator 1 4q23-q25 11763 9859 179502 NP_001093896;NP_001093897;NP_001093898;NP_001093899;NP_001093900;NP_066982;XP_006714347;XP_006714348 NM_001100426;NM_001100427;NM_001100428;NM_001100429;NM_001100430;NM_021159;XM_006714284;XM_006714285 ENSP00000340454 P52306 TRUE cgc 1 0 0 Metazoans 0 -1 chr4 99214555 99363265 |GDS1|SmgGDS| NP_001093896 0 FALSE 1 41 11862 0.1370
5914 RARA retinoic acid receptor, alpha 17q21 6769 9864 180240 NP_000955;NP_001019980;NP_001138773;NP_001138774;XP_005257609;XP_005257610;XP_005257611;XP_005257612 NM_000964;NM_001024809;NM_001033603;NM_001145301;NM_001145302;XM_005257552;XM_005257553;XM_005257554;XM_005257555 ENSP00000254066 P10276 TRUE cgc 1 0 1 Eukaryotes 3 Cell response to stimuli,Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction chr17 38497642 38512475 |NR1B1| XP_005257609 1 FALSE 1 138 75911 0.0780 9
5921 RASA1 RAS p21 protein activator (GTPase activating protein) 1 5q13.3 745 9871 139150 NP_002881;NP_072179 NM_002890;NM_022650 ENSP00000274376;ENSP00000378033 P20936 TRUE can 0 0 0 Eukaryotes 5 Cell cycle,Cell motility and interactions,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction chr5 86564269 86686697 |CM-AVM|CMAVM|PKWS|RASA|RASGAP|p120GAP|p120RASGAP| NP_002881 0 FALSE 2 101 39256 0.0990 11
5925 RB1 retinoblastoma 1 13q14.2 1574 9884 614041 NP_000312 NM_000321 ENSP00000267163 P06400 TRUE cgc 0 1 0 Eukaryotes 16 Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction chr13 48878049 49054204 |OSRC|PPP1R130|RB|p105-Rb|pRb|pp110| NP_000312 0 FALSE 12 241 199008 0.0570 30
5927 KDM5A lysine (K)-specific demethylase 5A 12p11 8915 9886 180202 NP_001036068 NM_001042603;NM_005056 ENSP00000382688 P29375 TRUE cgc 1 0 0 Eukaryotes 1 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr12 394625 498257 |RBBP-2|RBBP2| NP_001036068 0 FALSE 1 22 517 0.2770
5930 RBBP6 retinoblastoma binding protein 6 16p12.2 2964 9889 600938 NP_008841;NP_061173;NP_116015;XP_005255518;XP_005255519 NM_006910;NM_018703;NM_032626;XM_005255461;XM_005255462 ENSP00000317872 Q7Z6E9 TRUE can 0 0 0 Eukaryotes 0 Cellular metabolism,Cellular processes chr16 24551948 24583763 |MY038|P2P-R|RBQ-1|SNAMA| XP_005255518 0 FALSE 1 53 30582 0.0440
5966 REL v-rel avian reticuloendotheliosis viral oncogene homolog 2p13-p12 1286 9954 164910 NP_002899;XP_005264527;XP_005264528;XP_005264529 NM_002908;XM_005264470;XM_005264471;XM_005264472 ENSP00000295025 Q04864 TRUE cgc 1 0 0 Metazoans 1 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction chr2 61118814 61149667 |C-Rel| NP_002899 0 FALSE 1 222 377253 0.0150 21
5979 RET ret proto-oncogene 10q11.2 1266 9967 164761 NP_065681;NP_066124;XP_006717999 NM_000323;NM_020629;NM_020630;NM_020975;XM_006717936 ENSP00000347942 P07949 TRUE cgc 1 0 0 Eukaryotes 3 Cell motility and interactions,Cellular metabolism,Cellular processes,Development,Signal transduction chr10 43595894 43623714 |CDHF12|CDHR16|HSCR1|MEN2A|MEN2B|MTC1|RET-ELE1|RET51| NP_066124 0 FALSE 4 42 23200 0.1970 4
5987 TRIM27 tripartite motif containing 27 6p22 15996 9975 602165 NP_006501 NM_006510;NM_030950 ENSP00000366404;ENSP00000383555;ENSP00000392787;ENSP00000396844;ENSP00000405229;ENSP00000407959;ENSP00000414793 P14373 TRUE cgc 1 0 0 Eukaryotes 0 Cellular metabolism,DNA/RNA metabolism and transcription,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Regulation of transcription chr6 28871850 28891409 |RFP|RNF76| NP_006501 0 FALSE 1 267 314332 0.0190 1
6002 RGS12 regulator of G-protein signaling 12 4p16.3 3943 9994 602512 NP_002917;NP_937870;NP_937872;XP_006713968;XP_006713969;XP_006713970 NM_002926;NM_198227;NM_198229;NM_198230;NM_198430;NM_198432;NM_198587;XM_006713905;XM_006713906;XM_006713907;XR_427479 ENSP00000339381 O14924 TRUE can 0 0 0 Eukaryotes 0 Regulation of intracellular processes and metabolism,Signal transduction chr4 3317898 3441408 |NA| NP_937872 0 FALSE 1 18 14614 0.0720
6009 RHEB Ras homolog enriched in brain 7q36 3188 10011 601293 NP_005605;XP_006716144 NM_005614;XM_006716081 ENSP00000262187 Q15382 TRUE can 0 0 2 Eukaryotes 1 Signal transduction chr7 151164208 151216597 |RHEB2| NP_005605 2 FALSE 1 29 5716 0.0760 10
6014 RIT2 Ras-like without CAAX 2 18q12.3 15253 10017 609592 NP_001259006;NP_002921 NM_001272077;NM_002930 ENSP00000321805 Q99578 TRUE can 0 0 0 Eukaryotes 0 Multicellular activities,Signal transduction chr18 40323461 40695484 |RIBA|RIN| NP_002921 0 FALSE 1 12 4406 0.1670
6016 RIT1 Ras-like without CAAX 1 1q22 10195 10023 609591 NP_001243749;NP_001243750;NP_008843 NM_001256820;NM_001256821;NM_006912 ENSP00000349723 Q92963 TRUE can 0 0 0 Eukaryotes 3 Signal transduction chr1 155870182 155880597 |NS8|RIBB|RIT| NP_001243750 0 FALSE 1 19 3671 0.0760 2
6092 ROBO2 roundabout, axon guidance receptor, homolog 2 (Drosophila) 3p12.3 - 10250 602431 NP_001122401;NP_002933;XP_005264825;XP_005264826;XP_006713342 NM_001128929;NM_002942;XM_005264768;XM_005264769;XM_006713279 ENSP00000417335 Q9HCK4 TRUE can 0 0 0 Last Universal Common Ancestor 1 Cell cycle,Cell motility and interactions,Development,Regulation of intracellular processes and metabolism chr3 77089937 77694054 |NA| XP_005264825 0 FALSE 1 18 5202 0.0260
6098 ROS1 ROS proto-oncogene 1 , receptor tyrosine kinase 6q22 1295 10261 165020 NP_002935;XP_006715611 NM_002944;XM_006715548 ENSP00000357494 P08922 TRUE cgc 1 0 0 Eukaryotes 1 Cellular metabolism,Cellular processes,Signal transduction chr6 117609658 117746819 |MCF3|ROS|c-ros-1| NP_002935 0 FALSE 3 7 233 0.3330
6103 RPGR retinitis pigmentosa GTPase regulator Xp21.1 2425 10295 312610 NP_000319;NP_001030025;XP_005272690;XP_006724601 NM_000328;NM_001023582;NM_001034853;XM_005272633;XM_006724538 ENSP00000367766 Q92834 TRUE can 0 0 0 Last Universal Common Ancestor 1 Cell response to stimuli,Cellular processes chrX 38144796 38182778 |CORDX1|PCDX|RP15|XLRP3|orf15| NP_001030025 0 FALSE 1 15 3677 0.0670
6125 RPL5 ribosomal protein L5 1p22.1 4699 10360 603634 NP_000960 NM_000969 ENSP00000359345 P46777 TRUE cgc 0 0 27 Last Universal Common Ancestor 2 Cellular metabolism,Regulation of transcription chr1 93298946 93307419 |DBA6|PPP1R135| NP_000960 27 FALSE 2 160 29543 0.3130 14
6134 RPL10 ribosomal protein L10 Xq28 2421 10298 312173 NP_001243506;NP_001243509;NP_006004 NM_001256577;NM_001256580;NM_006013 ENSP00000259526;ENSP00000377061;ENSP00000469329 P27635 TRUE cgc 0 0 15 Last Universal Common Ancestor 2 Cellular metabolism,Regulation of transcription chrX 153627680 153629361 |AUTSX5|DXS648|QM| NP_001243506 6 FALSE 1 82 9035 0.3850 11
6146 RPL22 ribosomal protein L22 1p36.31 1602 10315 180474 NP_000974 NM_000983 ENSP00000346088 P35268 TRUE cgc 1 0 17 Eukaryotes 0 Cellular metabolism,Regulation of transcription chr1 6246735 6257816 |EAP|HBP15|HBP15/L22| NP_000974 17 FALSE 4 103 11815 0.3720 11
6184 RPN1 ribophorin I 3q21.3 1598 10381 180470 NP_002941 NM_002950 ENSP00000296255 P04843 TRUE cgc 1 0 0 Eukaryotes 2 Cellular metabolism,Cellular processes chr3 128339257 128369643 |OST1|RBPH1| NP_002941 0 FALSE 1 67 40946 0.1170 2
6197 RPS6KA3 ribosomal protein S6 kinase, 90kDa, polypeptide 3 Xp22.2-p22.1 2092 10432 300075 NP_004577;XP_005274630;XP_005274632;XP_005274633;XP_005274634;XP_006724568;XP_006724569;XP_006724570 NM_004586;XM_005274573;XM_005274575;XM_005274576;XM_005274577;XM_006724505;XM_006724506;XM_006724507 ENSP00000368884 P51812 TRUE can 0 0 2 Last Universal Common Ancestor 3 Cellular metabolism,Cellular processes,Development,Signal transduction chrX 20173519 20284750 |HU-3|ISPK-1|MAPKAPK1B|MRX19|RSK2|S6K-alpha3|p90-RSK2|pp90RSK2| NP_004577 2 FALSE 1 52 22049 0.0840
6232 RPS27 ribosomal protein S27 1q21 4744 10416 603702 NP_001021 NM_001030 ENSP00000357555 P42677 TRUE can 0 0 21 Last Universal Common Ancestor 2 Cellular metabolism,Regulation of transcription,Signal transduction chr12 3320832 3321083 |MPS-1|S27| NP_001021 21 FALSE 1 76 27007 0.2730 23
6249 CLIP1 CAP-GLY domain containing linker protein 1 12q24.3 1568 10461 179838 NP_001234926;NP_002947;NP_937883;XP_005253650;XP_005253651;XP_005253652;XP_006719614;XP_006719615;XP_006719616;XP_006719617;XP_006719618 NM_001247997;NM_002956;NM_198240;XM_005253593;XM_005253594;XM_005253595;XM_006719551;XM_006719552;XM_006719553;XM_006719554;XM_006719555 ENSP00000303585 P30622 TRUE can 0 0 0 Eukaryotes 5 Cell cycle chr12 122757425 122864999 |CLIP-170|CLIP170|CYLN1|RSN| XP_005253650 0 FALSE 1 28 1609 0.0930 8
6256 RXRA retinoid X receptor, alpha 9q34.3 - 10477 180245 NP_002948;XP_005263466;XP_006717295 NM_002957;XM_005263409;XM_006717232 ENSP00000419692;ENSP00000470812 P19793 TRUE can 0 0 0 Eukaryotes 0 Cell response to stimuli,Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction chr9 137293477 137328457 |NR2B1| NP_002948 0 FALSE 1 125 57383 0.0960 18
6261 RYR1 ryanodine receptor 1 (skeletal) 19q13.1 1618 10483 180901 NP_000531;NP_001036188;XP_006723380;XP_006723381;XP_006723382 NM_000540;NM_001042723;XM_006723317;XM_006723318;XM_006723319 ENSP00000352608 P21817 TRUE can 0 0 0 Last Universal Common Ancestor 0 Cellular processes,Multicellular activities,Regulation of intracellular processes and metabolism chr19 38924470 39078057 |CCO|MHS|MHS1|PPP1R137|RYDR|RYR|RYR-1|SKRR| NP_000531 0 FALSE 1 18 5639 0.0460 1
6262 RYR2 ryanodine receptor 2 (cardiac) 1q43 1619 10484 180902 NP_001026;XP_006711865;XP_006711866;XP_006711867;XP_006711868;XP_006711869;XP_006711870;XP_006711871;XP_006711872;XP_006711873 NM_001035;XM_006711802;XM_006711803;XM_006711804;XM_006711805;XM_006711806;XM_006711807;XM_006711808;XM_006711809;XM_006711810 ENSP00000355533 Q92736 TRUE can 0 0 0 Last Universal Common Ancestor 1 Cell cycle,Cellular processes,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Signal transduction chr1 237205822 237995944 |ARVC2|RYR-2|RyR|VTSIP| NP_001026 0 TRUE 2 24 8652 0.0760 1
6331 SCN5A sodium channel, voltage-gated, type V, alpha subunit 3p21 2543 10593 600163 NP_000326;NP_001092874;NP_001092875;NP_001153632;NP_001153633;NP_932173;XP_006713345;XP_006713346;XP_006713347 NM_000335;NM_001099404;NM_001099405;NM_001160160;NM_001160161;NM_198056;XM_006713282;XM_006713283;XM_006713284 ENSP00000328968 Q14524 TRUE can 0 0 0 Eukaryotes 0 Cellular processes,Multicellular activities chr3 38591815 38674798 |CDCD2|CMD1E|HBBD|ICCD|IVF|LQT3|Nav1.5|VF1| NP_001092874 0 FALSE 1 26 8871 0.0280 1
6335 SCN9A sodium channel, voltage-gated, type IX, alpha subunit 2q24 4565 10597 603415 NP_002968;XP_005246814 NM_002977;XM_005246757 ENSP00000386306 Q15858 TRUE can 0 0 3 Eukaryotes 1 Cellular processes chr2 167055185 167168266 |ETHA|FEB3B|GEFSP7|NE-NA|NENA|Nav1.7|SFNP| XP_005246814 3 FALSE 1
6336 SCN10A sodium channel, voltage-gated, type X, alpha subunit 3p22.2 9188 10582 604427 NP_006505;XP_005265428 NM_006514;XM_005265371 ENSP00000390600 Q9Y5Y9 TRUE can 0 0 0 Eukaryotes 0 Cell response to stimuli,Cellular processes chr3 38738843 38835501 |FEPS2|Nav1.8|PN3|SNS|hPN3| XP_005265428 0 FALSE 1 2 54 0.0000
6385 SDC4 syndecan 4 20q12 8366 10661 600017 NP_002990 NM_002999 ENSP00000361818 P31431 TRUE cgc 1 0 0 Vertebrates 5 -1 chr20 43955907 43977024 |SYND4| NP_002990 0 FALSE 1 20 3491 0.1160 5
6390 SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip) 1p36.1-p35 1707 10681 185470 NP_002991 NM_003000 ENSP00000364649 P21912 TRUE cgc 0 1 0 Last Universal Common Ancestor 1 Cellular metabolism chr1 17345379 17380514 |CWS2|PGL4|SDHIP| NP_002991 0 FALSE 1 46 11886 0.0700
6391 SDHC succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa 1q23.3 - 10682 602413 NP_001030588;NP_001030589;NP_001030590;NP_001265101;NP_002992 NM_001035511;NM_001035512;NM_001035513;NM_001278172;NM_003001;NR_103459 ENSP00000356953 Q99643 TRUE cgc 0 1 8 Last Universal Common Ancestor 3 Cellular metabolism chr17 1761336 1761740 |CYB560|CYBL|PGL3|QPS1|SDH3| NP_001030589 4 FALSE 1 3 4 0.6670
6392 SDHD succinate dehydrogenase complex, subunit D, integral membrane protein 11q23 4069 10683 602690 NP_001263432;NP_001263433;NP_001263435;NP_002993 NM_001276503;NM_001276504;NM_001276506;NM_003002;NR_077060 ENSP00000364699;ENSP00000456434 O14521 TRUE cgc 0 1 7 Opisthokonts 0 Cellular metabolism chr11 111957632 111965691 |CBT1|CII-4|CWS3|PGL|PGL1|QPs3|SDH4|cybS| NP_002993 7 FALSE 1
6406 SEMG1 semenogelin I 20q12-q13.2 1641 10742 182140 NP_002998 NM_003007;NM_198139 ENSP00000361867 P04279 TRUE can 0 0 1 Primates 0 Multicellular activities chr20 43835695 43837324 |CT103|SEMG|SGI|dJ172H20.2| NP_002998 1 FALSE 1 9 938 0.1390
6416 MAP2K4 mitogen-activated protein kinase kinase 4 17p12 3213 6844 601335 NP_001268364;NP_003001;XP_005256810;XP_005256812;XP_006721631 NM_001281435;NM_003010;XM_005256753;XM_005256755;XM_006721568 ENSP00000262445 P45985 TRUE cgc 0 1 1 Eukaryotes 2 Cellular metabolism,Cellular processes,Signal transduction chr17 11924204 12044574 |JNKK|JNKK1|MAPKK4|MEK4|MKK4|PRKMK4|SAPKK-1|SAPKK1|SEK1|SERK1|SKK1| NP_001268364 1 FALSE 3 46 10581 0.1330 7
6418 SET SET nuclear proto-oncogene 9q34 9023 10760 600960 NP_001116293;NP_001234929;NP_001234930;NP_003002 NM_001122821;NM_001248000;NM_001248001;NM_003011 ENSP00000361777 Q01105 TRUE cgc 1 0 11 Eukaryotes 3 Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism chr3 155705093 155705962 |2PP2A|I2PP2A|IGAAD|IPP2A2|PHAPII|TAF-I|TAF-IBETA| NP_001116293 11 FALSE 1 116 86322 0.0690 5
6421 SFPQ splicing factor proline/glutamine-rich 1p34.3 7284 10774 605199 NP_005057;XP_005271168;XP_005271169;XP_005271170;XP_005271172;XP_005271173 NM_005066;XM_005271111;XM_005271112;XM_005271113;XM_005271115;XM_005271116 ENSP00000349748 P23246 TRUE cgc 1 0 0 Metazoans 3 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr1 35650060 35658650 |POMP100|PPP1R140| NP_005057 0 FALSE 2 141 58473 0.1360 13
6426 SRSF1 serine/arginine-rich splicing factor 1 17q22 - 10780 600812 NP_001071634;NP_008855;XP_006722075 NM_001078166;NM_006924;NR_034041;XM_006722012;XR_429911;XR_429912 ENSP00000258962 Q07955 TRUE can 0 0 0 Eukaryotes 10 DNA/RNA metabolism and transcription,Regulation of transcription chr17 56082770 56084498 |SF2|SF2p33|SFRS1|SRp30a| NP_008855 0 FALSE 1 151 93424 0.1740 14
6427 SRSF2 serine/arginine-rich splicing factor 2 17q25.1 2888 10783 600813 NP_001182356;NP_003007 NM_001195427;NM_003016;NR_036608;XR_429913;XR_429914 ENSP00000353089 Q01130 TRUE cgc 1 0 1 Eukaryotes 6 DNA/RNA metabolism and transcription,Regulation of transcription chr17 74732246 74733242 |PR264|SC-35|SC35|SFRS2|SFRS2A|SRp30b| NP_001182356 1 FALSE 1 89 32015 0.1470 10
6428 SRSF3 serine/arginine-rich splicing factor 3 6p21 - 10785 603364 NP_003008 NM_003017;NR_036610 ENSP00000362820 P84103 TRUE cgc 1 0 4 Eukaryotes 2 DNA/RNA metabolism and transcription,Regulation of transcription chr11 18686597 18687095 |SFRS3|SRp20| NP_003008 4 FALSE 1 109 59196 0.1500 7
6446 SGK1 serum/glucocorticoid regulated kinase 1 6q23 4264 10810 602958 NP_001137148;NP_001137149;NP_001137150;NP_005618 NM_001143676;NM_001143677;NM_001143678;NM_005627 ENSP00000356832 O00141 TRUE can 0 0 0 Last Universal Common Ancestor 3 Cell cycle,Cellular metabolism,Cellular processes chr6 134491409 134638598 |SGK| NP_001137148 0 FALSE 2 91 65979 0.0570
6455 SH3GL1 SH3-domain GRB2-like 1 19p13.3 3462 10830 601768 NP_001186872;NP_001186873;NP_003016 NM_001199943;NM_001199944;NM_003025 ENSP00000269886 Q99961 TRUE cgc 1 0 3 Opisthokonts 1 Cellular processes,Development,Signal transduction chr19 4361600 4400365 |CNSA1|EEN|SH3D2B|SH3P8| NP_003016 3 FALSE 1 58 30865 0.1130
6476 SI sucrase-isomaltase (alpha-glucosidase) 3q25.2-q26.2 1962 10856 609845 NP_001032 NM_001041 ENSP00000264382;ENSP00000402758 P14410 TRUE can 0 0 0 Last Universal Common Ancestor 1 -1 chr3 164697153 164793800 |NA| NP_001032 0 FALSE 2 1 0 0.0000
6491 STIL SCL/TAL1 interrupting locus 1p32 1627 10879 181590 NP_001041631;NP_001269865;NP_001269866;NP_001269867;NP_001269868;NP_003026;XP_006710897;XP_006710898 NM_001048166;NM_001282936;NM_001282937;NM_001282938;NM_001282939;NM_003035;XM_006710834;XM_006710835 ENSP00000360944 Q15468 TRUE cgc 1 0 0 Eukaryotes 3 -1 chr1 47716811 47775991 |MCPH7| NP_001041631 0 FALSE 1 3 120 0.0000
6502 SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase 5p13 3256 10901 601436 NP_001230049;NP_005974;NP_116026;XP_006714550 NM_001243120;NM_005983;NM_032637;XM_006714487 ENSP00000274255 Q13309 TRUE can 0 0 0 Opisthokonts 2 Cell cycle chr5 36152871 36182130 |FBL1|FBXL1|FLB1| NP_005974 0 FALSE 1 113 55317 0.1040 20
6511 SLC1A6 solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6 19p13.12 9005 10944 600637 NP_001259016;NP_001259017;NP_005062;XP_006722905;XP_006722906;XP_006722907 NM_001272087;NM_001272088;NM_005071;NR_073589;XM_006722842;XM_006722843;XM_006722844 ENSP00000221742 P48664 TRUE can 0 0 0 Last Universal Common Ancestor 1 Cellular processes,Multicellular activities chr19 15061010 15083722 |EAAT4| NP_005062 0 FALSE 1 2 4 0.0000
6526 SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 21q22.12 2708 11038 600444 NP_008864 NM_006933 ENSP00000370543 NA TRUE can 0 0 0 Last Universal Common Ancestor 7 Cellular processes,Development,Multicellular activities chr21 35467498 35469651 |BCW2|SMIT|SMIT1| NP_008864 0 FALSE 1 2 13 0.0000
6530 SLC6A2 solute carrier family 6 (neurotransmitter transporter), member 2 16q12.2 1232 11048 163970 NP_001034;NP_001165972;NP_001165973;NP_001165975;XP_006721326 NM_001043;NM_001172501;NM_001172502;NM_001172504;XM_006721263 ENSP00000219833;ENSP00000347134;ENSP00000359042;ENSP00000434364 P23975 TRUE can 0 0 0 Last Universal Common Ancestor 0 Cell response to stimuli,Cellular processes,Multicellular activities chr16 55690607 55739181 |NA| NP_001165975 0 FALSE 1 5 140 0.1000
6538 SLC6A11 solute carrier family 6 (neurotransmitter transporter), member 11 3p25.3 - 11044 607952 NP_055044 NM_014229 ENSP00000254488 P48066 TRUE can 0 0 0 Last Universal Common Ancestor 0 Cellular processes chr3 10857951 10980085 |GAT-3|GAT4| NP_055044 0 FALSE 1
6564 SLC15A1 solute carrier family 15 (oligopeptide transporter), member 1 13q32.3 2768 10920 600544 NP_005064 NM_005073 ENSP00000365686 P46059 TRUE can 0 0 0 Last Universal Common Ancestor 1 Cellular processes chr13 99336981 99378703 |HPECT1|HPEPT1|PEPT1| NP_005064 0 FALSE 1 1 0 0.0000
6565 SLC15A2 solute carrier family 15 (oligopeptide transporter), member 2 3q13.33 9088 10921 602339 NP_001139470;NP_066568;XP_005247779;XP_005247780;XP_006713799 NM_001145998;NM_021082;XM_005247722;XM_005247723;XM_006713736 ENSP00000417085 Q16348 TRUE can 0 0 0 Last Universal Common Ancestor 1 Cellular processes chr3 121613324 121659851 |PEPT2| NP_066568 0 FALSE 1 2 17 0.0000
6594 SMARCA1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 Xq25 2055 11097 300012 NP_001269803;NP_001269804;NP_003060;XP_005262518;XP_005262519;XP_006724845 NM_001282874;NM_001282875;NM_003069;NM_139035;XM_005262461;XM_005262462;XM_006724782 ENSP00000360163 P28370 TRUE can 0 0 1 Eukaryotes 8 Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription chrX 128581142 128657347 |NURF140|SNF2L|SNF2L1|SNF2LT|SWI| NP_001269803 1 FALSE 1 22 396 0.2770 4
6597 SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 19p13.2 4459 11100 603254 NP_001122316;NP_001122317;NP_001122318;NP_001122319;NP_001122320;NP_001122321;NP_003063;XP_005260085;XP_005260087;XP_005260088;XP_005260089;XP_005260090;XP_005260091;XP_005260092;XP_006722908;XP_006722909;XP_006722910 NM_001128844;NM_001128845;NM_001128846;NM_001128847;NM_001128848;NM_001128849;NM_003072;XM_005260028;XM_005260030;XM_005260031;XM_005260032;XM_005260033;XM_005260034;XM_005260035;XM_006722845;XM_006722846;XM_006722847 ENSP00000350720 P51532 TRUE cgc 0 1 0 Eukaryotes 4 Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription chr19 11094828 11170875 |BAF190A|BRG1|MRD16|RTPS2|SNF2L4|hSNF2b| NP_001122321 0 FALSE 6 183 103549 0.0980 52
6598 SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 22q11.23|22q11 3364 11103 601607 NP_001007469;NP_003064 NM_001007468;NM_003073 ENSP00000263121 Q12824 TRUE cgc 0 1 0 Eukaryotes 4 Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Other,Regulation of intracellular processes and metabolism,Regulation of transcription chr22 24129357 24176364 |BAF47|INI1|MRD15|PPP1R144|RDT|RTPS1|SNF5|SNF5L1|SWNTS1|Sfh1p|Snr1|hSNFS| NP_003064 0 FALSE 2 104 42442 0.1320 53
6602 SMARCD1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1 12q13-q14 3438 11106 601735 NP_003067;NP_620710;XP_005269164 NM_003076;NM_139071;XM_005269107 ENSP00000378414 Q96GM5 TRUE can 0 0 0 Last Universal Common Ancestor 6 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr12 50478781 50492780 |BAF60A|CRACD1| XP_005269164 0 FALSE 1 81 26432 0.1160 34
6605 SMARCE1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 17q21.2 - 11109 603111 NP_003070 NM_003079 ENSP00000323967 Q969G3 TRUE cgc 0 0 6 Metazoans 4 Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr17 38785040 38798811 |BAF57| NP_003070 6 FALSE 1 107 58263 0.0970 38
6608 SMO smoothened, frizzled class receptor 7q32.3 3294 11119 601500 NP_005622 NM_005631 ENSP00000307252 Q99835 TRUE cgc 1 0 0 Eukaryotes 5 Cell cycle,Cell motility and interactions,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Signal transduction chr7 128828993 128852289 |FZD11|SMOH| NP_005622 0 FALSE 3 7 565 0.3330 7
6614 SIGLEC1 sialic acid binding Ig-like lectin 1, sialoadhesin 20p13 2854 11127 600751 NP_075556;XP_006723673;XP_006723674;XP_006723675;XP_006723676 NM_023068;XM_006723610;XM_006723611;XM_006723612;XM_006723613 ENSP00000341141 Q9BZZ2 TRUE can 0 0 0 Eukaryotes 0 Cell motility and interactions,Immune system response chr20 3669210 3687775 |CD169|SIGLEC-1|dJ1009E24.1| NP_075556 0 FALSE 1 3 31 0.0000
6626 SNRPA small nuclear ribonucleoprotein polypeptide A 19q13.1 1658 11151 182285 NP_004587 NM_004596 ENSP00000243563 P09012 TRUE can 0 0 0 Eukaryotes 0 DNA/RNA metabolism and transcription,Regulation of transcription chr19 41257314 41271069 |Mud1|U1-A|U1A| NP_004587 0 FALSE 1 84 19437 0.1600 10
6651 SON SON DNA binding protein 21q22.11 1678 11183 182465 NP_115571;NP_620305;XP_006724106;XP_006724107;XP_006724108 NM_003103;NM_032195;NM_138925;NM_138927;NR_103796;NR_103797;NR_103798;XM_006724043;XM_006724044;XM_006724045;XR_430355 ENSP00000348984 P18583 TRUE can 0 0 0 Metazoans 10 Cell cycle,Development,Regulation of intracellular processes and metabolism chr21 34915399 34948727 |BASS1|C21orf50|DBP-5|NREBP|SON3| NP_620305 0 FALSE 1 67 11815 0.1950
6657 SOX2 SRY (sex determining region Y)-box 2 3q26.3-q27 8921 11195 184429 NP_003097 NM_003106 ENSP00000323588 P48431 TRUE cgc 1 0 0 Eukaryotes 6 Cell response to stimuli,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Regulation of transcription chr3 181430149 181431099 |ANOP3|MCOPS3| NP_003097 0 FALSE 1 331 363709 0.0160 20
6660 SOX5 SRY (sex determining region Y)-box 5 12p12.1 18086 11201 604975 NP_001248343;NP_001248344;NP_008871;NP_694534;NP_821078;XP_006719212;XP_006719213 NM_001261414;NM_001261415;NM_006940;NM_152989;NM_178010;XM_006719149;XM_006719150 ENSP00000398273 P35711 TRUE can 0 0 0 Eukaryotes 5 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr12 23687156 24102535 |L-SOX5|L-SOX5B|L-SOX5F| NP_008871 0 FALSE 1 27 9919 0.0510
6662 SOX9 SRY (sex determining region Y)-box 9 17q24.3 6427 11204 608160 NP_000337 NM_000346 ENSP00000245479;ENSP00000324549;ENSP00000337513;ENSP00000353769;ENSP00000439856 P48436 TRUE can 0 0 0 Eukaryotes 6 Cell cycle,Cell motility and interactions,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Regulation of transcription chr17 70117533 70120525 |CMD1| NP_000337 0 FALSE 1 18 1459 0.1760 1
6701 SPRR2B small proline-rich protein 2B 1q21-q22 - - 182268 NP_001017418 NM_001017418 - P35325 TRUE can 0 0 6 - 0 Development chr1 153043100 153043315 |NA| NP_001017418 6 FALSE 1
6708 SPTA1 spectrin, alpha, erythrocytic 1 1q21 1685 11272 182860 NP_003117 NM_003126 ENSP00000357130 P02549 TRUE can 0 0 0 Metazoans 3 Cellular metabolism,Cellular processes,Development,Regulation of intracellular processes and metabolism chr1 158581057 158655137 |EL2|HS3|SPH3|SPTA| NP_003117 0 FALSE 3 27 1601 0.1200 5
6741 SSB Sjogren syndrome antigen B (autoantigen La) 2q31.1 168 11316 109090 NP_003133;XP_005246868 NM_003142;XM_005246811 ENSP00000260956 P05455 TRUE can 0 0 4 Eukaryotes 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of transcription chr2 170657471 170668263 |LARP3|La|La/SSB| NP_003133 4 FALSE 1 63 42411 0.1380 3
6756 SSX1 synovial sarcoma, X breakpoint 1 Xp11.23 2428 11335 312820 NP_001265620;NP_005626 NM_001278691;NM_005635 ENSP00000472663 Q16384 TRUE cgc 1 0 2 Mammals 3 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chrX 48116677 48125819 |CT5.1|SSRC| NP_001265620 2 FALSE 1 3 35 0.0000 1
6757 SSX2 synovial sarcoma, X breakpoint 2 Xp11.22 2180 11336 300192 NP_001265626;NP_003138;NP_783629 NM_001278697;NM_003147;NM_175698 ENSP00000364665;ENSP00000470740 NA TRUE cgc 1 0 2 Mammals 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chrX 52727082 52734799 |CT5.2A|HD21| NP_001265630 2 FALSE 1 20 2177 0.1580
6759 SSX4 synovial sarcoma, X breakpoint 4 Xp11.23 2266 11338 300326 NP_005627;NP_783856;XP_006726907 NM_005636;NM_175729;XM_006726844 ENSP00000366081;ENSP00000366083;ENSP00000469394 NA TRUE cgc 1 0 3 Mammals 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chrX 48262901 48270814 |NA| NP_001030004 3 FALSE 1 4 73 0.1670
6760 SS18 synovial sarcoma translocation, chromosome 18 18q11.2 2559 11340 600192 NP_001007560;NP_005628;XP_005258391;XP_006722590 NM_001007559;NM_005637;XM_005258334;XM_006722527 ENSP00000414516 Q15532 TRUE cgc 1 0 0 Eukaryotes 3 -1 chr18 23612363 23670533 |SSXT| NP_001007560 0 FALSE 1 28 22604 0.1880 2
6774 STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 17q21.31 26 11364 102582 NP_003141;NP_644805;NP_998827;XP_005257673;XP_005257674;XP_005257675 NM_003150;NM_139276;NM_213662;XM_005257616;XM_005257617;XM_005257618 ENSP00000264657 P40763 TRUE cgc 1 0 0 Eukaryotes 7 Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction chr17 40467766 40540577 |ADMIO|APRF|HIES| XP_005257673 0 FALSE 2 253 439647 0.0500 17
6775 STAT4 signal transducer and activator of transcription 4 2q32.2-q32.3 2779 11365 600558 NP_001230764;NP_003142;XP_005246874;XP_006712782 NM_001243835;NM_003151;XM_005246817;XM_006712719 ENSP00000351255 Q14765 TRUE can 0 0 0 Eukaryotes 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction chr2 191895683 192012929 |SLEB11| XP_005246874 0 FALSE 1 17 5242 0.1030
6777 STAT5B signal transducer and activator of transcription 5B 17q11.2 5037 11367 604260 NP_036580;XP_005257682;XP_005257683 NM_012448;XM_005257625;XM_005257626 ENSP00000293328 P51692 TRUE cgc 1 0 1 Eukaryotes 1 Cell cycle,Cell motility and interactions,Cell response to stimuli,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Immune system response,Multicellular activities,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction chr17 40353759 40384145 |NA| NP_036580 1 FALSE 1 65 25863 0.1460 11
6778 STAT6 signal transducer and activator of transcription 6, interleukin-4 induced 12q13 3302 11368 601512 NP_001171549;NP_001171550;NP_001171551;NP_001171552;NP_003144;XP_006719636;XP_006719637;XP_006719638 NM_001178078;NM_001178079;NM_001178080;NM_001178081;NM_003153;NR_033659;XM_006719573;XM_006719574;XM_006719575 ENSP00000300134 P42226 TRUE can 0 0 0 Eukaryotes 2 Cell cycle,Cell response to stimuli,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Immune system response,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction chr12 57490358 57502061 |D12S1644|IL-4-STAT|STAT6B|STAT6C| NP_001171549 0 FALSE 1 63 33249 0.0720 4
6781 STC1 stanniocalcin 1 8p21-p11.2 3115 11373 601185 NP_003146 NM_003155 ENSP00000290271 P52823 TRUE can 0 0 0 Metazoans 0 Cell response to stimuli,Regulation of intracellular processes and metabolism,Signal transduction chr8 23702286 23712036 |STC| NP_003146 0 FALSE 1
6794 STK11 serine/threonine kinase 11 19p13.3 - 11389 602216 NP_000446;XP_005259674;XP_005259675 NM_000455;XM_005259617;XM_005259618 ENSP00000324856 Q15831 TRUE cgc 0 1 0 Eukaryotes 2 Cell cycle,Cellular metabolism,Cellular processes chr19 1206913 1228078 |LKB1|PJS|hLKB1| XP_005259674 0 FALSE 4 113 108333 0.0370 5
6850 SYK spleen tyrosine kinase 9q22 2514 11491 600085 NP_001128524;NP_001167638;NP_001167639;NP_003168;XP_005252204 NM_001135052;NM_001174167;NM_001174168;NM_003177;XM_005252147 ENSP00000364898 P43405 TRUE cgc 1 0 0 Last Universal Common Ancestor 0 Cell cycle,Cell motility and interactions,Cell response to stimuli,Cellular metabolism,Cellular processes,Development,Immune system response,Regulation of intracellular processes and metabolism,Signal transduction chr9 93606181 93657879 |p72-Syk| NP_001167638 0 FALSE 2 129 173716 0.1110 30
6854 SYN2 synapsin II 3p25 2857 11495 600755 NP_003169;NP_598328;XP_006713374;XP_006713375;XP_006713376 NM_003178;NM_133625;XM_006713311;XM_006713312;XM_006713313 - Q92777 TRUE can 0 0 0 - 0 Cellular processes,Multicellular activities,Signal transduction chr3 12046026 12232122 |SYNII| NP_598328 0 FALSE 1 10 2806 0.1330 2
6860 SYT4 synaptotagmin IV 18q12.3 2519 11512 600103 NP_065834 NM_020783 ENSP00000255224 Q9H2B2 TRUE can 0 0 0 Eukaryotes 2 Cellular processes,Multicellular activities,Signal transduction chr18 40850309 40854360 |HsT1192| NP_065834 0 FALSE 1 10 1157 0.1560
6867 TACC1 transforming, acidic coiled-coil containing protein 1 8p11.22 10391 11522 605301 NP_001116296;NP_001139688;NP_006274;XP_005273679;XP_005273681;XP_005273682;XP_005273683;XP_005273684;XP_005273685;XP_005273686;XP_005273687;XP_005273688 NM_001122824;NM_001146216;NM_006283;XM_005273622;XM_005273624;XM_005273625;XM_005273626;XM_005273627;XM_005273628;XM_005273629;XM_005273630;XM_005273631 ENSP00000321703 O75410 TRUE can 0 0 0 Metazoans 2 -1 chr8 38645074 38705538 |Ga55| XP_005273679 0 FALSE 1 23 4351 0.0400 3
6872 TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa Xq13.1 2436 11535 313650 NP_001273003;NP_004597;NP_620278;XP_005262352;XP_005262353;XP_005262354;XP_005262357;XP_006724743;XP_006724744;XP_006724745 NM_001286074;NM_004606;NM_138923;NR_104387;NR_104388;NR_104389;NR_104390;NR_104391;NR_104392;NR_104393;NR_104394;NR_104395;NR_104396;XM_005262295;XM_005262296;XM_005262297;XM_005262300;XM_006724680;XM_006724681;XM_006724682 ENSP00000276072 P21675 TRUE can 0 0 1 Eukaryotes 5 Cell cycle,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chrX 70586165 70683893 |BA2R|CCG1|CCGS|DYT3|DYT3/TAF1|N-TAF1|P250|TAF(II)250|TAFII-250|TAFII250|XDP| XP_005262352 1 FALSE 1 71 24177 0.1190 26
6886 TAL1 T-cell acute lymphocytic leukemia 1 1p32 1753 11556 187040 NP_001274276;NP_003180;XP_005271215;XP_005271216;XP_005271217;XP_006710925;XP_006710926 NM_001287347;NM_003189;XM_005271158;XM_005271159;XM_005271160;XM_006710862;XM_006710863 ENSP00000294339 P17542 TRUE cgc 1 0 0 Metazoans 0 Cellular metabolism,DNA/RNA metabolism and transcription,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Regulation of transcription chr1 47685395 47691560 |TCL5|bHLHa17|tal-1| NP_001274276 0 FALSE 1 53 9149 0.1280 5
6887 TAL2 T-cell acute lymphocytic leukemia 2 9q32 1735 11557 186855 NP_005412 NM_005421 ENSP00000334547 Q16559 TRUE cgc 1 0 0 Vertebrates 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr9 108424778 108425101 |NA| NP_005412 0 FALSE 1 9 174 0.2500
6917 TCEA1 transcription elongation factor A (SII), 1 8q11.2 3252 11612 601425 NP_006747;NP_958845;XP_006716530 NM_006756;NM_201437;NR_109901;NR_109902;XM_006716467 ENSP00000428426 P23193 TRUE cgc 1 0 2 Last Universal Common Ancestor 1 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr8 54882952 54934685 |GTF2S|SII|TCEA|TF2S| NP_006747 2 FALSE 1 51 8923 0.1110 4
6921 TCEB1 transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C) 8q21.11 2875 11617 600788 NP_001191786;NP_001191787;NP_001191788;NP_001191789;NP_001191790;NP_001191791;NP_001191792;NP_001191793;NP_005639;XP_005251347 NM_001204857;NM_001204858;NM_001204859;NM_001204860;NM_001204861;NM_001204862;NM_001204863;NM_001204864;NM_005648;XM_005251290 ENSP00000284811 Q15369 TRUE can 0 0 9 Eukaryotes 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr8 74858868 74868290 |eloC| NP_001191786 9 FALSE 1 105 71078 0.0630 33
6926 TBX3 T-box 3 12q24.21 3373 11602 601621 NP_005987;NP_057653 NM_005996;NM_016569 ENSP00000257566 O15119 TRUE can 0 0 0 Metazoans 3 Cell cycle,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Multicellular activities,Other,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction chr12 115109649 115121005 |TBX3-ISO|UMS|XHL| NP_057653 0 FALSE 1 10 982 0.2890
6927 HNF1A HNF1 homeobox A 12q24.2 800 11621 142410 NP_000536;XP_005253988 NM_000545;XM_005253931 ENSP00000257555 P20823 TRUE cgc 0 1 0 Metazoans 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr12 121416572 121438992 |HNF-1A|HNF1|LFB1|MODY3|TCF1| XP_005253988 0 FALSE 1 49 25683 0.0840
6928 HNF1B HNF1 homeobox B 17q12 8926 11630 189907 NP_000449;NP_001159395 NM_000458;NM_001165923;NM_006481 ENSP00000225893 P35680 TRUE can 0 0 0 Metazoans 2 Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription chr17 36059082 36104875 |HNF-1B|HNF1beta|HNF2|HPC11|LF-B3|LFB3|MODY5|TCF-2|TCF2|VHNF1| NP_000449 0 FALSE 1 6 64 0.4000
6929 TCF3 transcription factor 3 19p13.3 918 11633 147141 NP_001129611;NP_003191;XP_005259677;XP_006722915;XP_006722916;XP_006722917;XP_006722918;XP_006722919;XP_006722920;XP_006722921;XP_006722922;XP_006722923;XP_006722924;XP_006722925;XP_006722926 NM_001136139;NM_003200;XM_005259620;XM_006722852;XM_006722853;XM_006722854;XM_006722855;XM_006722856;XM_006722857;XM_006722858;XM_006722859;XM_006722860;XM_006722861;XM_006722862;XM_006722863;XR_430150;XR_430151;XR_430152;XR_430153 ENSP00000375639;ENSP00000458632;ENSP00000470149;ENSP00000470971;ENSP00000471904;ENSP00000472186;ENSP00000472539;ENSP00000472608;ENSP00000473133 P15923 TRUE cgc 1 0 1 Metazoans 4 Cellular metabolism,DNA/RNA metabolism and transcription,Development,Immune system response,Regulation of intracellular processes and metabolism,Regulation of transcription chr19 1611709 1650247 |E2A|E47|ITF1|VDIR|bHLHb21| XP_005259677 1 FALSE 1 153 175838 0.0360 16
6934 TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box) 10q25.3 3751 11641 602228 NP_001139746;NP_001139755;NP_001139756;NP_001139757;NP_001139758;NP_001185454;NP_001185455;NP_001185456;NP_001185457;NP_001185458;NP_001185459;NP_001185460;NP_110383;XP_005270128;XP_005270130;XP_005270131;XP_005270132;XP_005270133;XP_005270134;XP_005270135;XP_005270136;XP_005270137;XP_005270139;XP_005270140;XP_005270141;XP_005270142;XP_005270143;XP_005270145;XP_005270146;XP_005270148;XP_005270149;XP_005270150;XP_005270151;XP_005270152;XP_005270153;XP_005270154;XP_005270155;XP_005270156;XP_005270157;XP_005270158;XP_005270159;XP_005270160;XP_005270161;XP_005270162;XP_006718018;XP_006718019;XP_006718020;XP_006718021 NM_001146274;NM_001146283;NM_001146284;NM_001146285;NM_001146286;NM_001198525;NM_001198526;NM_001198527;NM_001198528;NM_001198529;NM_001198530;NM_001198531;NM_030756;XM_005270071;XM_005270073;XM_005270074;XM_005270075;XM_005270076;XM_005270077;XM_005270078;XM_005270079;XM_005270080;XM_005270082;XM_005270083;XM_005270084;XM_005270085;XM_005270086;XM_005270088;XM_005270089;XM_005270091;XM_005270092;XM_005270093;XM_005270094;XM_005270095;XM_005270096;XM_005270097;XM_005270098;XM_005270099;XM_005270100;XM_005270101;XM_005270102;XM_005270103;XM_005270104;XM_005270105;XM_006717955;XM_006717956;XM_006717957;XM_006717958 ENSP00000346440;ENSP00000444972 Q9NQB0 TRUE cgc 1 0 0 Metazoans 0 Cell cycle,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction chr10 114710516 114925728 |NA| XP_005270128 0 FALSE 1 24 2400 0.1740 12
6938 TCF12 transcription factor 12 15q21 2725 11623 600480 NP_003196;NP_996919;NP_996920;NP_996921;NP_996923;XP_005254670;XP_006720721;XP_006720722 NM_003205;NM_207036;NM_207037;NM_207038;NM_207040;XM_005254613;XM_006720658;XM_006720659 ENSP00000331057 Q99081 TRUE cgc 1 0 0 Metazoans 3 Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription chr15 57212112 57574782 |HEB|HTF4|HsT17266|bHLHb20| NP_996919 0 FALSE 2 65 77800 0.0470 1
6955 TRA T cell receptor alpha locus 14q11.2 - - - - - - NA TRUE cgc 1 0 -1 - 0 Cell response to stimuli - 0 0 |TRA@| - -1 FALSE 1
6957 TRB T cell receptor beta locus 7q34 - - - - - - NA TRUE cgc 1 0 -1 - 0 -1 - 0 0 |TRB@| - -1 FALSE 1
6964 TRD T cell receptor delta locus 14q11.2 - - - - - - NA TRUE cgc 1 0 -1 - 0 -1 - 0 0 |TCRDV1|TRD@| - -1 FALSE 1
6996 TDG thymine-DNA glycosylase 12q24.1 3251 11700 601423 NP_003202;XP_005269182 NM_001008411;NM_003211;XM_005269125;XR_429113 ENSP00000376611 Q13569 TRUE can 0 0 1 Last Universal Common Ancestor 3 Cellular metabolism,DNA/RNA metabolism and transcription chr12 104370694 104380865 |hTDG| NP_003202 1 FALSE 1 39 3647 0.2040 2
7015 TERT telomerase reverse transcriptase 5p15.33 1754 11730 187270 NP_001180305;NP_937983 NM_001193376;NM_198253;NM_198254;NM_198255;XR_241712;XR_241713 ENSP00000309572 O14746 TRUE cgc 1 0 0 Eukaryotes 5 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism chr5 1253846 1295104 |CMM9|DKCA2|DKCB4|EST2|PFBMFT1|TRT|hEST2|hTRT| NP_937983 0 FALSE 2 70 43143 0.0890 4
7027 TFDP1 transcription factor Dp-1 13q34 1792 11749 189902 NP_009042;XP_005268383;XP_005268384;XP_005268385;XP_005268387;XP_005268388;XP_006720040;XP_006720041 NM_007111;NR_026580;XM_005268326;XM_005268327;XM_005268328;XM_005268330;XM_005268331;XM_006719977;XM_006719978 ENSP00000364519 Q14186 TRUE can 0 0 4 Eukaryotes 0 Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription chr13 114265311 114294579 |DRTF1|Dp-1| NP_009042 4 FALSE 1 35 4762 0.1950 21
7030 TFE3 transcription factor binding to IGHM enhancer 3 Xp11.22 2439 11752 314310 NP_001269071;NP_006512;XP_006724612 NM_001282142;NM_006521;XM_006724549 ENSP00000314129;ENSP00000470141 P19532 TRUE cgc 1 0 0 Metazoans 1 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chrX 48887672 48900752 |RCCX1|TFEA|bHLHe33| NP_006512 0 FALSE 1 45 5284 0.0430
7037 TFRC transferrin receptor 3q29 1812 11763 190010 NP_001121620;NP_003225 NM_001128148;NM_003234 ENSP00000353224 P02786 TRUE cgc 1 0 0 Last Universal Common Ancestor 4 Cellular processes,Regulation of intracellular processes and metabolism chr3 195778816 195802231 |CD71|TFR|TFR1|TRFR| NP_001121620 0 FALSE 1 57 46156 0.0570 4
7048 TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 3p22 1823 11773 190182 NP_001020018;NP_003233;XP_006713379 NM_001024847;NM_003242;XM_006713316 ENSP00000351905 P37173 TRUE can 0 0 0 Metazoans 15 Cell cycle,Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism,Signal transduction chr3 30648376 30733088 |AAT3|FAA3|LDS1B|LDS2|LDS2B|MFS2|RIIC|TAAD2|TGFR-2|TGFbeta-RII| NP_001020018 0 FALSE 4 67 84868 0.0880 45
7057 THBS1 thrombospondin 1 15q15 - 11785 188060 NP_003237 NM_003246 ENSP00000260356 P07996 TRUE can 0 0 0 Last Universal Common Ancestor 14 -1 chr15 39874059 39886640 |THBS|THBS-1|TSP|TSP-1| NP_003237 0 FALSE 1 49 33217 0.0820 11
7062 TCHH trichohyalin 1q21.3 - 11791 190370 NP_009044 NM_007113 ENSP00000357794 Q07283 TRUE can 0 0 0 Vertebrates 0 Development chr1 152079864 152086556 |THH|THL|TRHY| NP_009044 0 FALSE 1 2 186 0.0000
7080 NKX2-1 NK2 homeobox 1 14q13 2798 11825 600635 NP_001073136;NP_003308 NM_001079668;NM_003317 ENSP00000346879 P43699 TRUE cgc 1 0 0 Metazoans 2 Cell cycle,Cell motility and interactions,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription chr14 36986486 36989334 |BHC|NK-2|NKX2.1|NKX2A|T/EBP|TITF1| NP_001073136 0 FALSE 1 21 1642 0.1810
7091 TLE4 transducin-like enhancer of split 4 9q21.31 - 11840 605132 NP_001269677;NP_001269678;NP_001269682;NP_001269689;NP_008936;XP_005252224;XP_005252226;XP_005252230;XP_005252231;XP_005252232;XP_005252234;XP_006717327;XP_006717328;XP_006717329;XP_006717330;XP_006717331;XP_006717332;XP_006717333 NM_001282748;NM_001282749;NM_001282753;NM_001282760;NM_007005;NR_104239;XM_005252167;XM_005252169;XM_005252173;XM_005252174;XM_005252175;XM_005252177;XM_006717264;XM_006717265;XM_006717266;XM_006717267;XM_006717268;XM_006717269;XM_006717270 ENSP00000365735 Q04727 TRUE can 0 0 1 Eukaryotes 10 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction chr9 82187706 82340056 |BCE-1|BCE1|E(spI)|ESG4|GRG4|Grg-4| XP_005252224 1 FALSE 1 14 1668 0.0550 11
7092 TLL1 tolloid-like 1 4q32-q33 7074 11843 606742 NP_001191689;NP_036596;XP_005263249;XP_006714356 NM_001204760;NM_012464;XM_005263192;XM_006714293 ENSP00000061240 O43897 TRUE can 0 0 1 Eukaryotes 1 Cellular metabolism,Development chr4 166795057 167022025 |ASD6| NP_036596 1 FALSE 1 2 187 0.0000
7093 TLL2 tolloid-like 2 10q23-q24 5993 11844 606743 NP_036597 NM_012465 ENSP00000350630 Q9Y6L7 TRUE can 0 0 1 Eukaryotes 0 Cellular metabolism chr10 98127848 98273442 |NA| NP_036597 1 FALSE 1
7097 TLR2 toll-like receptor 2 4q32 - 11848 603028 NP_003255;XP_005263250;XP_005263251;XP_005263252;XP_005263253;XP_005263254 NM_003264;XM_005263193;XM_005263194;XM_005263195;XM_005263196;XM_005263197 ENSP00000260010 O60603 TRUE can 0 0 0 Eukaryotes 5 Cell cycle,Cell response to stimuli,Cellular processes,Development,Immune system response,Regulation of intracellular processes and metabolism,Signal transduction chr4 154624060 154626411 |CD282|TIL4| NP_003255 0 FALSE 1 35 14249 0.0620 17
7099 TLR4 toll-like receptor 4 9q33.1 4325 11850 603030 NP_003257;NP_612564;NP_612567 NM_003266;NM_138554;NM_138556;NM_138557 ENSP00000363089 O00206 TRUE can 0 0 0 Eukaryotes 5 Cell response to stimuli,Cellular metabolism,Development,Immune system response,Regulation of intracellular processes and metabolism,Signal transduction chr9 120466751 120476923 |ARMD10|CD284|TLR-4|TOLL| NP_612564 0 FALSE 3 40 39678 0.1180 37
7113 TMPRSS2 transmembrane protease, serine 2 21q22.3 3637 11876 602060 NP_001128571;NP_005647;XP_005261099;XP_005261100;XP_005261101;XP_006724111 NM_001135099;NM_005656;XM_005261042;XM_005261043;XM_005261044;XM_006724048 ENSP00000381588 O15393 TRUE cgc 1 0 0 Last Universal Common Ancestor 0 Cellular metabolism chr21 42839661 42879931 |PP9284|PRSS10| NP_001128571 0 FALSE 1
7117 TMSB4XP8 thymosin beta 4, X-linked pseudogene 8 4q22.1 - 11885 - - NM_183049 - NA TRUE can 0 0 -1 - 0 Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism - 0 0 |TMSL3| - -1 FALSE 1
7124 TNF tumor necrosis factor 6p21.3 1855 11892 191160 NP_000585 NM_000594 ENSP00000365290;ENSP00000372988;ENSP00000389265;ENSP00000389490;ENSP00000389492;ENSP00000392858;ENSP00000398698;ENSP00000410668 P01375 TRUE can 0 0 0 Vertebrates 1 Cell cycle,Cell motility and interactions,Cell response to stimuli,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Immune system response,Multicellular activities,Other,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction chr6 31543519 31545311 |DIF|TNF-alpha|TNFA|TNFSF2| NP_000585 0 FALSE 1 73 49166 0.0840 6
7128 TNFAIP3 tumor necrosis factor, alpha-induced protein 3 6q23 1857 11896 191163 NP_001257436;NP_001257437;NP_006281;XP_005267176;XP_006715618 NM_001270507;NM_001270508;NM_006290;XM_005267119;XM_006715555 ENSP00000237289 P21580 TRUE cgc 0 1 0 Metazoans 3 Cell cycle,Development,Regulation of intracellular processes and metabolism,Signal transduction chr6 138192365 138202453 |OTUD7C|TNFA1P2| NP_001257436 0 FALSE 1 77 29521 0.1190 1
7130 TNFAIP6 tumor necrosis factor, alpha-induced protein 6 2q23.3 2680 11898 600410 NP_009046 NM_007115 ENSP00000243347 P98066 TRUE can 0 0 0 Eukaryotes 0 Immune system response,Signal transduction chr2 152214181 152236044 |TSG-6|TSG6| NP_009046 0 FALSE 1 3 2527 0.0000
7143 TNR tenascin R 1q24 - 11953 601995 NP_003276 NM_003285 ENSP00000263525 Q92752 TRUE can 0 0 0 Eukaryotes 0 Cell cycle,Cell motility and interactions,Development,Signal transduction chr1 175292496 175375850 |TN-R| NP_003276 0 FALSE 1 15 4683 0.0190 1
7150 TOP1 topoisomerase (DNA) I 20q12-q13.1 535 11986 126420 NP_003277 NM_003286 ENSP00000354522 P11387 TRUE cgc 1 0 0 Last Universal Common Ancestor 5 Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription chr20 39690033 39751934 |TOPI| NP_003277 0 FALSE 1 135 67807 0.1460 15
7157 TP53 tumor protein p53 17p13.1 1859 11998 191170 NP_000537;NP_001119584;NP_001119585;NP_001119586;NP_001119587;NP_001119588;NP_001119589;NP_001119590;NP_001263624;NP_001263625;NP_001263626;NP_001263627;NP_001263628;NP_001263689;NP_001263690 NM_000546;NM_001126112;NM_001126113;NM_001126114;NM_001126115;NM_001126116;NM_001126117;NM_001126118;NM_001276695;NM_001276696;NM_001276697;NM_001276698;NM_001276699;NM_001276760;NM_001276761 ENSP00000269305 P04637 TRUE cgc 0 1 0 Opisthokonts 16 Cell cycle,Cell response to stimuli,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction chr17 7572930 7579912 |BCC7|LFS1|P53|TRP53| NP_000537 0 FALSE 22 859 1922407 0.0330 43
7170 TPM3 tropomyosin 3 1q21.2 1840 12012 191030 NP_001036816;NP_001036817;NP_001036818;NP_001265117;NP_001265118;NP_001265119;NP_001265120;NP_689476;NP_705935;XP_006711578;XP_006711579;XP_006711580;XP_006711581;XP_006711582;XP_006711583;XP_006711584;XP_006711585;XP_006711586 NM_001043351;NM_001043352;NM_001043353;NM_001278188;NM_001278189;NM_001278190;NM_001278191;NM_152263;NM_153649;NR_103460;NR_103461;XM_006711515;XM_006711516;XM_006711517;XM_006711518;XM_006711519;XM_006711520;XM_006711521;XM_006711522;XM_006711523 ENSP00000267996;ENSP00000357516 P06753 TRUE cgc 1 0 2 Metazoans 6 Multicellular activities chr1 154141783 154164494 |CAPM1|HEL-189|HEL-S-82p|OK/SW-cl.5|TM-5|TM3|TM30|TM30nm|TM5|TPMsk3|hscp30| NP_689476 2 FALSE 1 95 91834 0.0770 5
7171 TPM4 tropomyosin 4 19p13.1 11734 12013 600317 NP_001138632;NP_003281;XP_005260099;XP_006722928 NM_001145160;NM_003290;XM_005260042;XM_006722865 ENSP00000267996;ENSP00000357516 P67936 TRUE cgc 1 0 5 Metazoans 4 -1 chr19 16178435 16212153 |HEL-S-108| NP_001138632 5 FALSE 1 46 6925 0.1290 4
7173 TPO thyroid peroxidase 2p25 6000 12015 606765 NP_000538;NP_001193673;NP_001193674;NP_783650;NP_783652;NP_783653;XP_005264755;XP_005264756;XP_005264757;XP_005264758;XP_005264759;XP_005264761;XP_005264762 NM_000547;NM_001206744;NM_001206745;NM_175719;NM_175720;NM_175721;NM_175722;XM_005264698;XM_005264699;XM_005264700;XM_005264701;XM_005264702;XM_005264704;XM_005264705;XR_426959 ENSP00000204615 P07202 TRUE can 0 0 0 Last Universal Common Ancestor 2 Cell response to stimuli,Cellular metabolism chr2 1418181 1544684 |MSA|TDH2A|TPX| XP_005264755 0 FALSE 1 2 0 1.0000
7175 TPR translocated promoter region, nuclear basket protein 1q25 8927 12017 189940 NP_003283;XP_005245528 NM_003292;XM_005245471 ENSP00000356448 P12270 TRUE cgc 1 0 0 Eukaryotes 1 Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Regulation of transcription chr1 186283106 186344760 |NA| XP_005245528 0 FALSE 1 70 8824 0.1580 2
7187 TRAF3 TNF receptor-associated factor 3 14q32.32 3539 12033 601896 NP_001186356;NP_003291;NP_663777;NP_663778;XP_006720307 NM_001199427;NM_003300;NM_145725;NM_145726;XM_006720244 ENSP00000376500 Q13114 TRUE can 0 0 0 Eukaryotes 1 Cell cycle,Development,Regulation of intracellular processes and metabolism,Signal transduction chr14 103336539 103372118 |CAP-1|CD40bp|CRAF1|IIAE5| NP_003291 0 FALSE 1 107 55329 0.0650 22
7188 TRAF5 TNF receptor-associated factor 5 1q32 3834 12035 602356 NP_001029082;NP_004610;NP_665702;XP_005273306;XP_006711587 NM_001033910;NM_004619;NM_145759;XM_005273249;XM_006711524 ENSP00000261464 O00463 TRUE can 0 0 0 Eukaryotes 0 Cell cycle,Regulation of intracellular processes and metabolism,Signal transduction chr1 211500041 211546041 |MGC:39780|RNF84| XP_005273306 0 FALSE 1 56 20615 0.0930 1
7216 TRO trophinin Xp11.22-p11.21 2134 12326 300132 NP_001034794;NP_001258112;NP_001258113;NP_057241;NP_808224;NP_808225;XP_006724662;XP_006724663;XP_006724664;XP_006724665;XP_006724666;XP_006724667;XP_006724668 NM_001039705;NM_001271183;NM_001271184;NM_016157;NM_177556;NM_177557;NR_073148;NR_073149;XM_006724599;XM_006724600;XM_006724601;XM_006724602;XM_006724603;XM_006724604;XM_006724605 ENSP00000173898 Q12816 TRUE can 0 0 0 Eukaryotes 0 Cell motility and interactions,Development chrX 54948680 54957450 |MAGE-d3|MAGED3| NP_001034794 0 FALSE 1 9 911 0.1390 1
7227 TRPS1 trichorhinophalangeal syndrome I 8q24.12 5091 12340 604386 NP_001269831;NP_001269832;NP_054831;XP_005251106;XP_006716687;XP_006716688 NM_001282902;NM_001282903;NM_014112;XM_005251049;XM_006716624;XM_006716625 ENSP00000379065 Q9UHF7 TRUE can 0 0 0 Eukaryotes 8 Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription chr8 116426254 116632285 |GC79| NP_054831 0 FALSE 1 5 31 0.5000
7248 TSC1 tuberous sclerosis 1 9q34 5594 12362 605284 NP_000359;NP_001155898;NP_001155899;XP_005272268;XP_006717334;XP_006717335 NM_000368;NM_001008567;NM_001162426;NM_001162427;XM_005272211;XM_006717271;XM_006717272 ENSP00000298552 Q92574 TRUE cgc 0 1 0 Opisthokonts 2 Cell cycle,Cell motility and interactions,Cell response to stimuli,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction chr9 135771625 135804259 |NA| NP_000359 0 FALSE 5 59 28940 0.0680 17
7249 TSC2 tuberous sclerosis 2 16p13.3 1850 12363 191092 NP_000539;NP_001070651;NP_001107854;XP_005255584;XP_005255585;XP_005255586;XP_005255587;XP_005255588;XP_005255589 NM_000548;NM_001077183;NM_001114382;NM_021055;NM_021056;XM_005255527;XM_005255528;XM_005255529;XM_005255530;XM_005255531;XM_005255532 ENSP00000219476 P49815 TRUE cgc 0 1 0 Eukaryotes 0 Cell cycle,Cell motility and interactions,Cellular processes,Development,Regulation of intracellular processes and metabolism,Signal transduction chr16 2097823 2138608 |PPP1R160|TSC4| XP_005255584 0 FALSE 5 54 22639 0.1210 17
7253 TSHR thyroid stimulating hormone receptor 14q31 4537 12373 603372 NP_000360;NP_001018046;NP_001136098;XP_005268094;XP_005268096;XP_006720308 NM_000369;NM_001018036;NM_001142626;XM_005268037;XM_005268039;XM_006720245 ENSP00000298171 P16473 TRUE cgc 1 0 0 Metazoans 5 Cell cycle,Regulation of intracellular processes and metabolism,Signal transduction chr14 81422025 81610694 |CHNG1|LGR3|hTSHR-I| NP_000360 0 FALSE 1 24 17858 0.1050 4
7272 TTK TTK protein kinase 6q14.1 4973 12401 604092 NP_001160163;NP_003309 NM_001166691;NM_003318 ENSP00000358813 P33981 TRUE can 0 0 0 Last Universal Common Ancestor 4 Cell cycle,Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism chr6 80715561 80751916 |CT96|ESK|MPH1|MPS1L1|PYT| NP_003309 0 FALSE 1 23 11822 0.1230
7273 TTN titin 2q31 1787 12403 188840 NP_001243779;NP_001254479;NP_003310;NP_596869;NP_596870;NP_597676;NP_597681;XP_005246888;XP_006712786;XP_006712787;XP_006712788 NM_001256850;NM_001267550;NM_003319;NM_133378;NM_133379;NM_133432;NM_133437;XM_005246831;XM_006712723;XM_006712724;XM_006712725 ENSP00000343764 Q8WZ42 TRUE can 0 0 0 Eukaryotes 0 Cell cycle,Cellular metabolism,Cellular processes,Development,Multicellular activities,Signal transduction chr2 179583892 179669369 |CMD1G|CMH9|CMPD4|EOMFC|HMERF|LGMD2J|MYLK5|TMD| NP_001254479 0 TRUE 4 104 77962 0.0580 3
7278 TUBA3C tubulin, alpha 3c 13q11 3958 12408 602528 NP_005992 NM_006001;NM_079836 ENSP00000326042;ENSP00000382982 NA TRUE can 0 0 16 Eukaryotes 0 Cellular metabolism,Cellular processes chr13 19748006 19753703 |TUBA2|bA408E5.3| NP_005992 16 FALSE 1 58 9554 0.1630 2
7307 U2AF1 U2 small nuclear RNA auxiliary factor 1 21q22.3 1871 12453 191317 NP_001020374;NP_001020375;NP_006749 NM_001025203;NM_001025204;NM_006758 ENSP00000246532;ENSP00000291552;ENSP00000292879;ENSP00000472696 Q7Z780 TRUE cgc 1 0 2 Eukaryotes 0 DNA/RNA metabolism and transcription,Regulation of transcription chr21 44513215 44527604 |FP793|RNU2AF1|U2AF35|U2AFBP| NP_001020374 2 FALSE 2 108 16193 0.1920 15
7314 UBB ubiquitin B 17p12-p11.2 6771 12463 191339 NP_001268645;NP_001268646;NP_001268647;NP_001268648;NP_001268649;NP_061828 NM_001281716;NM_001281717;NM_001281718;NM_001281719;NM_001281720;NM_018955 ENSP00000272317;ENSP00000304697;ENSP00000388107 P0CG47 TRUE can 0 0 17 Last Universal Common Ancestor 1 Cell cycle,Cell motility and interactions,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Regulation of transcription chr17 16285222 16285908 |NA| NP_001268645 17 FALSE 1 134 61491 0.0890 97
7319 UBE2A ubiquitin-conjugating enzyme E2A Xq24 2422 12472 312180 NP_001269090;NP_003327;NP_861427 NM_001282161;NM_003336;NM_181762;NM_181777 ENSP00000360613 P49459 TRUE can 0 0 1 Eukaryotes 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism chrX 118708675 118717215 |HHR6A|MRXS30|MRXSN|RAD6A| NP_003327 1 FALSE 1 53 23553 0.0690 2
7321 UBE2D1 ubiquitin-conjugating enzyme E2D 1 10q21.1 4267 12474 602961 NP_001191809;NP_003329 NM_001204880;NM_003338 ENSP00000363019 P51668 TRUE can 0 0 4 Eukaryotes 4 Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism,Signal transduction chr10 60121098 60128522 |E2(17)KB1|SFT|UBCH5|UBCH5A| NP_003329 4 FALSE 1 234 213344 0.0290 17
7365 UGT2B10 UDP glucuronosyltransferase 2 family, polypeptide B10 4q13.2 - 12544 600070 NP_001066;NP_001138239 NM_001075;NM_001144767 ENSP00000265403;ENSP00000449012 P36537 TRUE can 0 0 9 Last Universal Common Ancestor 0 -1 chr4 69681738 69696594 |UDPGT2B10| NP_001066 9 FALSE 1 1 0 0.0000
7399 USH2A Usher syndrome 2A (autosomal recessive, mild) 1q41 2042 12601 608400 NP_009054;NP_996816 NM_007123;NM_206933 ENSP00000305941 O75445 TRUE can 0 0 0 Metazoans 4 Cell response to stimuli,Development,Regulation of intracellular processes and metabolism chr1 215799126 216595678 |RP39|US2|USH2|dJ1111A8.1| NP_996816 0 FALSE 4 4 80 0.1670
7403 KDM6A lysine (K)-specific demethylase 6A Xp11.2 2131 12637 300128 NP_066963;XP_005272712;XP_005272713;XP_005272714;XP_005272715;XP_005272716;XP_005272717;XP_005272718 NM_021140;XM_005272655;XM_005272656;XM_005272657;XM_005272658;XM_005272659;XM_005272660;XM_005272661;XR_430507 ENSP00000367203 O15550 TRUE cgc 0 1 1 Eukaryotes 0 DNA/RNA metabolism and transcription chrX 44732798 44969494 |KABUK2|UTX|bA386N14.2| XP_005272712 1 FALSE 9 27 20240 0.1880 2
7428 VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase 3p25.3 - 12687 608537 NP_000542;NP_937799 NM_000551;NM_198156 ENSP00000256474 P40337 TRUE cgc 0 1 1 Metazoans 4 Cell cycle,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription chr3 10183532 10191646 |VHL1|pVHL| NP_000542 1 FALSE 3 411 629008 0.0340 17
7430 EZR ezrin 6q25.3 475 12691 123900 NP_001104547;NP_003370;XP_006715624 NM_001111077;NM_003379;XM_006715561 ENSP00000338934;ENSP00000342830 P15311 TRUE cgc 1 0 0 Eukaryotes 3 Cell motility and interactions,Cellular processes,Development,Regulation of intracellular processes and metabolism chr6 159187949 159210403 |CVIL|CVL|HEL-S-105|VIL2| NP_001104547 0 FALSE 1 117 144774 0.0590 7
7450 VWF von Willebrand factor 12p13.3 1906 12726 613160 NP_000543 NM_000552 ENSP00000261405 P04275 TRUE can 0 0 0 Eukaryotes 0 Cellular metabolism,Multicellular activities chr12 6058184 6232362 |F8VWF|VWD| NP_000543 0 FALSE 1 20 11047 0.0530 19
7454 WAS Wiskott-Aldrich syndrome Xp11.4-p11.21 2314 12731 300392 NP_000368 NM_000377 ENSP00000365891;ENSP00000469374 P42768 TRUE cgc 0 1 0 Eukaryotes 0 Cellular metabolism,Cellular processes,Development,Immune system response,Multicellular activities chrX 48542243 48549550 |SCNX|THC|THC1|WASP| NP_000368 0 FALSE 1 75 20590 0.0900 16
7455 ZAN zonadhesin 7q22 3846 12857 602372 NP_003377;NP_775082 NM_003386;NM_173055;NM_173056;NM_173057;NM_173058;NM_173059 - Q9Y493 TRUE can 0 0 0 - 0 Cell motility and interactions,Development chr7 100331792 100395244 |NA| NP_003377 0 FALSE 1
7468 WHSC1 Wolf-Hirschhorn syndrome candidate 1 4p16.3 4259 12766 602952 NP_001035889;NP_015627;NP_579877;NP_579878;NP_579889;NP_579890;XP_005248058;XP_005248059;XP_005248062;XP_006713977;XP_006713978 NM_001042424;NM_007331;NM_014919;NM_133330;NM_133331;NM_133332;NM_133333;NM_133334;NM_133335;NM_133336;XM_005248001;XM_005248002;XM_005248005;XM_006713914;XM_006713915 ENSP00000372347 O96028 TRUE cgc 1 0 0 Last Universal Common Ancestor 4 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr4 1902382 1980633 |MMSET|NSD2|REIIBP|TRX5|WHS| NP_001035889 0 FALSE 1 136 38535 0.0900
7472 WNT2 wingless-type MMTV integration site family member 2 7q31.2 999 12780 147870 NP_003382;XP_006716172 NM_003391;NR_024047;XM_006716109 ENSP00000265441 P09544 TRUE can 0 0 1 Metazoans 2 Cell cycle,Cell motility and interactions,Cell response to stimuli,Cellular metabolism,Cellular processes,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Signal transduction chr7 116918212 116963043 |INT1L1|IRP| NP_003382 1 FALSE 1 8 1358 0.0360 1
7486 WRN Werner syndrome, RecQ helicase-like 8p12 5212 12791 604611 NP_000544 NM_000553 ENSP00000298139 Q14191 TRUE cgc 0 1 0 Last Universal Common Ancestor 0 Cell cycle,Cell response to stimuli,Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism chr8 30915964 31030615 |RECQ3| NP_000544 0 FALSE 1 39 2417 0.2620 4
7490 WT1 Wilms tumor 1 11p13 6163 12796 607102 NP_000369;NP_001185480;NP_001185481;NP_077742;NP_077744 NM_000378;NM_001198551;NM_001198552;NM_024424;NM_024425;NM_024426 ENSP00000331327 P19544 TRUE cgc 0 1 0 Eukaryotes 3 Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr11 32410607 32456888 |AWT1|EWS-WT1|GUD|NPHS4|WIT-2|WT33| NP_077744 0 FALSE 2 33 8896 0.0620 1
7494 XBP1 X-box binding protein 1 22q12.1|22q12 1908 12801 194355 NP_001073007;NP_005071 NM_001079539;NM_005080 ENSP00000216037 P17861 TRUE can 0 0 0 Metazoans 4 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr22 29191166 29196512 |TREB5|XBP-1|XBP2| NP_001073007 0 FALSE 1 27 5495 0.0680
7507 XPA xeroderma pigmentosum, complementation group A 9q22.3 2045 12814 611153 NP_000371;XP_006717341 NM_000380;NR_027302;XM_006717278;XR_428536 ENSP00000364270 P23025 TRUE cgc 0 1 0 Eukaryotes 3 Cellular metabolism,DNA/RNA metabolism and transcription chr9 100437724 100459574 |XP1|XPAC| NP_000371 0 FALSE 1 41 5669 0.1000 4
7508 XPC xeroderma pigmentosum, complementation group C 3p25.1 2046 12816 613208 NP_001139241;NP_004619 NM_001145769;NM_004628;NR_027299;XR_427290 ENSP00000285021 Q01831 TRUE cgc 0 1 0 Eukaryotes 1 Cell cycle,Cell response to stimuli,Cellular metabolism,DNA/RNA metabolism and transcription,Signal transduction chr3 14187444 14220068 |RAD4|XP3|XPCC|p125| NP_004619 0 FALSE 1 36 4894 0.1250 5
7512 XPNPEP2 X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound Xq25 2144 12823 300145 NP_003390 NM_003399 ENSP00000360147 O43895 TRUE can 0 0 0 Last Universal Common Ancestor 0 Cellular metabolism chrX 128873190 128902458 |AEACEI|APP2| NP_003390 0 FALSE 1
7514 XPO1 exportin 1 2p15 3975 12825 602559 NP_003391;XP_005264601;XP_005264603;XP_006712157;XP_006712158;XP_006712159;XP_006712160 NM_003400;XM_005264544;XM_005264546;XM_006712094;XM_006712095;XM_006712096;XM_006712097 ENSP00000384863 O14980 TRUE cgc 1 0 0 Eukaryotes 6 Cell response to stimuli,Cellular processes,DNA/RNA metabolism and transcription chr2 61705958 61761032 |CRM1|emb|exp1| NP_003391 0 FALSE 1 185 153533 0.0620 22
7531 YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon 17p13.3 5457 12851 605066 NP_006752;XP_005256841;XP_006725361 NM_006761;NR_024058;XM_005256784;XM_006725298 ENSP00000264335 P62258 TRUE cgc 1 0 5 Eukaryotes 1 Signal transduction chr17 1248744 1303404 |14-3-3E|HEL2| NP_006752 5 FALSE 1 347 400732 0.0450 39
7543 ZFX zinc finger protein, X-linked Xp21.3 2445 12869 314980 NP_001171555;NP_001171556;NP_001171557;NP_001171566;NP_003401;XP_005274648;XP_005274649;XP_005274651;XP_006724576;XP_006724577;XP_006724578 NM_001178084;NM_001178085;NM_001178086;NM_001178095;NM_003410;XM_005274591;XM_005274592;XM_005274594;XM_006724513;XM_006724514;XM_006724515 ENSP00000304985 P17010 TRUE can 0 0 1 Last Universal Common Ancestor 3 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chrX 24190860 24229490 |ZNF926| NP_001171555 1 FALSE 1
7547 ZIC3 Zic family member 3 Xq26.2 2225 12874 300265 NP_003404 NM_003413 ENSP00000287538 O60481 TRUE can 0 0 0 Eukaryotes 1 Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription chrX 136648851 136652226 |HTX|HTX1|VACTERLX|ZNF203| NP_003404 0 FALSE 1 5 87 0.2000
7555 CNBP CCHC-type zinc finger, nucleic acid binding protein 3q21 - 13164 116955 NP_001120664;NP_001120665;NP_001120666;NP_001120667;NP_001120668;NP_003409 NM_001127192;NM_001127193;NM_001127194;NM_001127195;NM_001127196;NM_003418 ENSP00000410769 P62633 TRUE cgc 1 0 0 Eukaryotes 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr3 128889299 128890600 |CNBP1|PROMM|RNF163|ZCCHC22|ZNF9| NP_001120664 0 FALSE 1 65 20438 0.1070
7652 ZNF99 zinc finger protein 99 19p12 - - 603981 NP_001073878 NM_001080409 ENSP00000380293 A8MXY4 TRUE can 0 0 -1 Eukaryotes 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription - 0 0 |C19orf9|F8281| - -1 FALSE 1
7681 MKRN3 makorin ring finger protein 3 15q11-q13 4836 7114 603856 NP_005655 NM_005664 ENSP00000313881 Q13064 TRUE can 0 0 0 Eukaryotes 0 -1 chr15 23810930 23812450 |CPPB2|D15S9|RNF63|ZFP127|ZNF127| NP_005655 0 FALSE 1 51 13248 0.0660
7704 ZBTB16 zinc finger and BTB domain containing 16 11q23.1 11762 12930 176797 NP_001018011;NP_005997;XP_005271715;XP_006718962 NM_001018011;NM_006006;XM_005271658;XM_006718899 ENSP00000338157 Q05516 TRUE cgc 1 0 0 Eukaryotes 0 Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription chr11 113934023 114121274 |PLZF|ZNF145| NP_001018011 0 FALSE 2 120 141321 0.0630
7750 ZMYM2 zinc finger, MYM-type 2 13q11-q12 3745 12989 602221 NP_001177893;NP_001177894;NP_003444;NP_932072;XP_005266574;XP_005266575;XP_005266576;XP_005266577;XP_005266578;XP_006719927 NM_001190964;NM_001190965;NM_003453;NM_197968;XM_005266517;XM_005266518;XM_005266519;XM_005266520;XM_005266521;XM_006719864 ENSP00000372322 Q9UBW7 TRUE cgc 1 0 0 Metazoans 3 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr13 20567213 20660151 |FIM|ZNF198| NP_001177893 0 FALSE 2 38 5478 0.1370 11
7757 ZNF208 zinc finger protein 208 19p12 - 12999 603977 NP_009084 NM_007153 ENSP00000380315 O43345 TRUE can 0 0 31 Eukaryotes 1 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr19 22153996 22157610 |PMIDP|ZNF95| NP_009084 31 FALSE 1 1 0 0.0000
7769 ZNF226 zinc finger protein 226 19q13.2 15751 13019 - NP_001027544;NP_001027545;NP_001027546;NP_001139692;NP_057003;XP_005259281;XP_005259282;XP_005259283;XP_005259284;XP_005259285;XP_006723430;XP_006723431;XP_006723432 NM_001032372;NM_001032373;NM_001032374;NM_001032375;NM_001146220;NM_015919;NM_016444;XM_005259224;XM_005259225;XM_005259226;XM_005259227;XM_005259228;XM_006723367;XM_006723368;XM_006723369 ENSP00000336719 Q9NYT6 TRUE can 0 0 0 Last Universal Common Ancestor 3 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr19 44679650 44681824 |NA| NP_001027544 0 FALSE 1 2 9 0.0000
7786 MAP3K12 mitogen-activated protein kinase kinase kinase 12 12q13 2709 6851 600447 NP_001180440;NP_006292;XP_005269195;XP_005269197;XP_006719651;XP_006719652 NM_001193511;NM_006301;XM_005269138;XM_005269140;XM_006719588;XM_006719589 ENSP00000448689 Q12852 TRUE can 0 0 0 Last Universal Common Ancestor 3 Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Signal transduction chr12 53874969 53881175 |MEKK12|MUK|ZPK|ZPKP1| NP_001180440 0 FALSE 1 17 4414 0.1760
7812 CSDE1 cold shock domain containing E1, RNA-binding 1p22 15949 29905 191510 NP_001007554;NP_001123995;NP_001229820;NP_001229821;NP_001229822;NP_009089 NM_001007553;NM_001130523;NM_001242891;NM_001242892;NM_001242893;NM_007158 ENSP00000407724 O75534 TRUE can 0 0 0 Eukaryotes 3 Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription chr1 115260793 115284285 |D1S155E| NP_001229820 0 FALSE 1 40 12131 0.1590 1
7832 BTG2 BTG family, member 2 1q32 3357 1131 601597 NP_006754 NM_006763 ENSP00000290551 P78543 TRUE can 0 0 0 Eukaryotes 9 Cell cycle,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription chr1 203274735 203276563 |TIS21| NP_006754 0 FALSE 2 22 17025 0.1170
7837 PXDN peroxidasin homolog (Drosophila) 2p25 - 14966 605158 NP_036425;XP_005264764;XP_006711959 NM_012293;XM_005264707;XM_006711896 ENSP00000252804;ENSP00000352962 Q92626 TRUE can 0 0 0 Last Universal Common Ancestor 8 Cell response to stimuli,Cellular metabolism chr2 1637979 1748227 |COPOA|D2S448|D2S448E|MG50|VPO| NP_036425 0 FALSE 1 3 358 0.0000
7840 ALMS1 Alstrom syndrome 1 2p13 6023 428 606844 NP_055935 NM_015120 ENSP00000264448 Q8TCU4 TRUE can 0 0 0 Metazoans 3 Cell response to stimuli chr2 73613033 73836736 |ALSS| NP_055935 0 FALSE 1 8 541 0.0710 11
7844 RNF103 ring finger protein 103 2p11.2 3939 12859 602507 NP_001185880;NP_001185881;NP_005658 NM_001198951;NM_001198952;NM_005667 ENSP00000237455 O00237 TRUE can 0 0 0 Eukaryotes 0 Development chr2 86830969 86850009 |HKF-1|KF-1|KF1|ZFP-103|ZFP103| NP_005658 0 FALSE 1 10 141 0.0220 1
7849 PAX8 paired box 8 2q13 1335 8622 167415 NP_003457;NP_039246;NP_039247;NP_054698 NM_003466;NM_013951;NM_013952;NM_013953;NM_013992 ENSP00000395498 Q06710 TRUE cgc 1 0 0 Metazoans 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr2 113976113 114004497 |NA| NP_003457 0 FALSE 1 19 4671 0.0530
7881 KCNAB1 potassium voltage-gated channel, shaker-related subfamily, beta member 1 3q26.1 3089 6228 601141 NP_003462;NP_751891;NP_751892;XP_005247810;XP_005247811 NM_003471;NM_172159;NM_172160;XM_005247753;XM_005247754 ENSP00000419952 Q14722 TRUE can 0 0 0 Last Universal Common Ancestor 0 Cellular processes chr3 155838401 156254533 |AKR6A3|KCNA1B|KV-BETA-1|Kvb1.3|hKvBeta3|hKvb3| NP_751892 0 FALSE 1 12 12444 0.1360 1
7913 DEK DEK proto-oncogene 6p22.3 503 2768 125264 NP_001128181;NP_003463;XP_005249448 NM_001134709;NM_003472;XM_005249391 ENSP00000380414 P35659 TRUE cgc 1 0 0 Eukaryotes 4 Cellular metabolism,DNA/RNA metabolism and transcription,Other,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction chr6 18226405 18264218 |D6S231E| NP_003463 0 FALSE 1 48 21433 0.1550 4
7942 TFEB transcription factor EB 6p21 2847 11753 600744 NP_001161299;NP_001258872;NP_001258873;NP_001258874;NP_009093;XP_005249468;XP_005249469;XP_006715275;XP_006715276 NM_001167827;NM_001271943;NM_001271944;NM_001271945;NM_007162;XM_005249411;XM_005249412;XM_006715212;XM_006715213 ENSP00000230323 P19484 TRUE cgc 1 0 0 Opisthokonts 4 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr6 41652340 41658972 |ALPHATFEB|BHLHE35|TCFEB| NP_001161299 0 FALSE 1 5 170 0.3000
7955 RNF217-AS1 RNF217 antisense RNA 1 (head to head) 6q22.33 - 50866 602532 - NR_026876 - NA TRUE cgc 1 0 -1 - 0 -1 - 0 0 |STL| - -1 FALSE 1
7976 FZD3 frizzled class receptor 3 8p21 5849 4041 606143 NP_059108;NP_665873 NM_017412;NM_145866 ENSP00000240093;ENSP00000461417 Q9NPG1 TRUE can 0 0 0 Eukaryotes 2 Development,Signal transduction chr8 28360531 28420525 |Fz-3| NP_059108 0 FALSE 1 4 251 0.0000 3
7994 KAT6A K(lysine) acetyltransferase 6A 8p11 3244 13013 601408 NP_001092882;NP_001092883;NP_006757;XP_005273706 NM_001099412;NM_001099413;NM_006766;XM_005273649 ENSP00000265713 Q92794 TRUE cgc 1 0 0 Eukaryotes 2 Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription chr8 41789726 41906495 |MOZ|MYST3|RUNXBP2|ZC2HC6A|ZNF220| NP_001092882 0 FALSE 2 25 5560 0.2030 2
8013 NR4A3 nuclear receptor subfamily 4, group A, member 3 9q22 2766 7982 600542 NP_008912;NP_775291;NP_775292;XP_005252294 NM_006981;NM_173198;NM_173199;NM_173200;XM_005252237 ENSP00000333122;ENSP00000370912 Q92570 TRUE cgc 1 0 0 Metazoans 4 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr9 102590322 102626146 |CSMF|MINOR| NP_775292 0 FALSE 1 6 657 0.2000 1
8019 BRD3 bromodomain containing 3 9q34 3327 1104 601541 NP_031397;XP_005272271;XP_006717354 NM_007371;XM_005272214;XM_006717291 ENSP00000305918 Q15059 TRUE cgc 1 0 0 Eukaryotes 3 -1 chr9 136898715 136918599 |ORFX|RING3L| NP_031397 0 FALSE 2 10 2791 0.1330
8021 NUP214 nucleoporin 214kDa 9q34.1 258 8064 114350 NP_005076;XP_005272273;XP_005272274;XP_005272275;XP_005272276;XP_006717355 NM_005085;XM_005272216;XM_005272217;XM_005272218;XM_005272219;XM_006717292 ENSP00000352400 P35658 TRUE cgc 1 0 0 Eukaryotes 1 Cellular processes,DNA/RNA metabolism and transcription chr9 134000969 134106158 |CAN|D9S46E|N214| XP_005272273 0 FALSE 1 46 8924 0.1280 3
8028 MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 10p12 3874 16063 602409 NP_001182555;NP_001182556;NP_001182557;NP_001182559;NP_004632;XP_005252662;XP_005252663;XP_005252665;XP_005252666;XP_005252667;XP_005252668;XP_005252669;XP_006717572 NM_001009569;NM_001195626;NM_001195627;NM_001195628;NM_001195630;NM_004641;XM_005252605;XM_005252606;XM_005252608;XM_005252609;XM_005252610;XM_005252611;XM_005252612;XM_006717509;XR_428648 ENSP00000307411 P55197 TRUE cgc 1 0 0 Eukaryotes 1 -1 chr10 21823574 22030909 |AF10| XP_005252662 0 FALSE 1 12 1943 0.2120
8030 CCDC6 coiled-coil domain containing 6 10q21 9064 18782 601985 NP_005427 NM_005436 ENSP00000263102 Q16204 TRUE cgc 1 0 0 Eukaryotes 4 -1 chr10 61552678 61666182 |D10S170| NP_005427 0 FALSE 2 23 2331 0.2170
8031 NCOA4 nuclear receptor coactivator 4 10q11.2 3584 7671 601984 NP_001138732;NP_001138733;NP_001138734;NP_001138735;NP_005428 NM_001145260;NM_001145261;NM_001145262;NM_001145263;NM_005437 ENSP00000395465;ENSP00000463027 Q13772 TRUE cgc 1 0 3 Metazoans 0 Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction chr10 51568357 51586672 |ARA70|ELE1|PTC3|RFG| NP_001138732 3 FALSE 1 11 87 0.3450
8085 KMT2D lysine (K)-specific methyltransferase 2D 12q13.12 3664 7133 602113 NP_003473;XP_005269219;XP_006719677;XP_006719678;XP_006719679 NM_003482;XM_005269162;XM_006719614;XM_006719615;XM_006719616 ENSP00000301067 O14686 TRUE cgc 0 1 0 Last Universal Common Ancestor 7 Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription chr12 49415566 49449107 |AAD10|CAGL114|KABUK1|TNRC21| NP_003473 0 FALSE 10 26 1489 0.2120 5
8087 FXR1 fragile X mental retardation, autosomal homolog 1 3q28 2892 4023 600819 NP_001013456;NP_001013457;NP_005078;XP_005247870;XP_005247871;XP_005247872;XP_005247873;XP_006713838 NM_001013438;NM_001013439;NM_005087;XM_005247813;XM_005247814;XM_005247815;XM_005247816;XM_006713775 ENSP00000350170 P51114 TRUE can 0 0 1 Eukaryotes 5 Cell cycle,Development chr3 180630096 180694077 |FXR1P| XP_005247870 1 FALSE 1 32 5449 0.1130 2
8091 HMGA2 high mobility group AT-hook 2 12q15 2827 5009 600698 NP_003474;NP_003475;XP_005269221;XP_006719683 NM_001015886;NM_003483;NM_003484;XM_005269164;XM_006719620;XR_245958 ENSP00000384026 P52926 TRUE cgc 1 0 0 Vertebrates 16 Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr12 66219051 66346207 |BABL|HMGI-C|HMGIC|LIPO|STQTL9| XP_005269221 0 FALSE 1 25 1401 0.1600 1
8115 TCL1A T-cell leukemia/lymphoma 1A 14q32.1 1744 11648 186960 NP_001092195;NP_068801 NM_001098725;NM_021966;NR_049726 ENSP00000385036 P56279 TRUE cgc 1 0 0 Mammals 4 -1 chr14 96178095 96180403 |TCL1| NP_001092195 0 FALSE 1 25 6693 0.0470 3
8148 TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa 17q11.1-q11.2 9031 11547 601574 NP_003478;NP_631961 NM_003487;NM_139215 ENSP00000263974 Q92804 TRUE cgc 1 0 0 Eukaryotes 7 -1 chr17 34144719 34172043 |Npl3|RBP56|TAF2N|TAFII68| NP_631961 0 FALSE 1 56 11096 0.1780 2
8178 ELL elongation factor RNA polymerase II 19p13.1 2615 23114 600284 NP_006523 NM_006532 ENSP00000262809 P55199 TRUE cgc 1 0 0 Metazoans 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr19 18555565 18632865 |C19orf17|ELL1|MEN|PPP1R68| NP_006523 0 FALSE 1 21 2757 0.2240 4
8216 LZTR1 leucine-zipper-like transcription regulator 1 22q11.21|22q11.1-q11.2 8992 6742 600574 NP_006758 NM_006767 ENSP00000215739 Q8N653 TRUE can 0 0 0 Last Universal Common Ancestor 0 -1 chr22 21336661 21351634 |BTBD29|LZTR-1|SWNTS2| NP_006758 0 FALSE 1 49 40891 0.0190
8218 CLTCL1 clathrin, heavy chain-like 1 22q11.21 3172 2093 601273 NP_001826;NP_009029;XP_005261338;XP_005277857;XP_005277858;XP_006724389;XP_006724390;XP_006724391 NM_001835;NM_007098;XM_005261281;XM_005277800;XM_005277801;XM_006724326;XM_006724327;XM_006724328 ENSP00000445677;ENSP00000468946 P53675 TRUE cgc 1 0 1 Eukaryotes 0 Cellular processes chr22 19168245 19279164 |CHC22|CLH22|CLTCL|CLTD| XP_005277857 1 FALSE 1 20 2399 0.1740
8233 ZRSR2 zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 2 Xp22.1 2068 23019 300028 NP_005080;XP_005274654;XP_006724582;XP_006724583 NM_005089;XM_005274597;XM_006724519;XM_006724520 ENSP00000303015 Q15696 TRUE cgc 0 1 2 Eukaryotes 0 DNA/RNA metabolism and transcription,Regulation of transcription chrX 15808619 15841362 |U2AF1-RS2|U2AF1L2|U2AF1RS2| NP_005080 2 FALSE 1 10 812 0.4440 2
8239 USP9X ubiquitin specific peptidase 9, X-linked Xp11.4 2091 12632 300072 NP_001034679;NP_001034680;XP_005272732;XP_005272733 NM_001039590;NM_001039591;NM_004652;NM_021906;XM_005272675;XM_005272676 ENSP00000316357 Q93008 TRUE can 0 0 1 Eukaryotes 2 Cellular metabolism,Multicellular activities chrX 40982882 41091774 |DFFRX|FAM| XP_005272732 1 FALSE 1 107 49338 0.0850 8
8241 RBM10 RNA binding motif protein 10 Xp11.23 2095 9896 300080 NP_001191395;NP_001191396;NP_001191397;NP_005667;NP_690595;XP_005272734;XP_005272735;XP_005272736;XP_006724626 NM_001204466;NM_001204467;NM_001204468;NM_005676;NM_152856;XM_005272677;XM_005272678;XM_005272679;XM_006724563 ENSP00000366829 P98175 TRUE can 0 0 0 Eukaryotes 0 -1 chrX 47004846 47045995 |DXS8237E|GPATC9|GPATCH9|S1-1|TARPS|ZRANB5| NP_001191397 0 FALSE 1 55 10734 0.1700
8242 KDM5C lysine (K)-specific demethylase 5C Xp11.22-p11.21 2442 11114 314690 NP_001140174;NP_001269551;NP_004178;XP_005262092;XP_006724672 NM_001146702;NM_001282622;NM_004187;XM_005262035;XM_006724609 ENSP00000364550;ENSP00000471752 P41229 TRUE cgc 0 1 1 Eukaryotes 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chrX 53222152 53254071 |DXS1272E|JARID1C|MRXJ|MRXSCJ|MRXSJ|SMCX|XE169| NP_004178 1 FALSE 1 21 2557 0.1620
8243 SMC1A structural maintenance of chromosomes 1A Xp11.22-p11.21 2077 11111 300040 NP_001268392;NP_006297 NM_001281463;NM_006306 ENSP00000323421;ENSP00000471583 Q14683 TRUE can 0 0 0 Last Universal Common Ancestor 2 Cell cycle,Cellular processes,DNA/RNA metabolism and transcription,Regulation of transcription,Signal transduction chrX 53407027 53449549 |CDLS2|DXS423E|SB1.8|SMC1|SMC1L1|SMC1alpha|SMCB| NP_006297 0 FALSE 2 92 39090 0.1040 38
8289 ARID1A AT rich interactive domain 1A (SWI-like) 1p35.3 4319 11110 603024 NP_006006;NP_624361 NM_006015;NM_018450;NM_139135 ENSP00000320485 O14497 TRUE cgc 0 1 0 Metazoans 6 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction chr1 27022895 27107244 |B120|BAF250|BAF250a|BM029|C1orf4|ELD|MRD14|OSA1|P270|SMARCF1|hELD|hOSA1| NP_006006 0 FALSE 16 45 8190 0.2460 28
8294 HIST1H4I histone cluster 1, H4i 6p21.33 - 4793 602833 NP_003486 NM_003495 ENSP00000289352;ENSP00000343282;ENSP00000346316;ENSP00000347168;ENSP00000348258;ENSP00000350159;ENSP00000350767;ENSP00000352980;ENSP00000353624;ENSP00000358153;ENSP00000358162;ENSP00000366581;ENSP00000366974;ENSP00000367034;ENSP00000462355;ENSP00000462667 NA TRUE cgc 1 0 14 Last Universal Common Ancestor 2 -1 chr1 149804249 149804557 |H4/m|H4FM|H4M| NP_001029249 14 FALSE 1 59 23073 0.1190 38
8295 TRRAP transformation/transcription domain-associated protein 7q21.2-q22.1 4310 12347 603015 NP_001231509;NP_003487 NM_001244580;NM_003496 ENSP00000347733;ENSP00000457834 Q9Y4A5 TRUE cgc 1 0 0 Eukaryotes 5 Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction chr7 98478774 98609975 |PAF350/400|PAF400|STAF40|TR-AP|Tra1| NP_001231509 0 FALSE 3 76 23753 0.1420 40
8301 PICALM phosphatidylinositol binding clathrin assembly protein 11q14 4320 15514 603025 NP_001008660;NP_001193875;NP_001193876;NP_009097;XP_005274379;XP_005274380;XP_005274381;XP_005274382;XP_005274383;XP_005274384;XP_005274385;XP_005274386;XP_005274387;XP_005274388;XP_005274389;XP_005274390;XP_005274391;XP_005274392;XP_005274393;XP_005274394;XP_005274395;XP_005274397;XP_006718762;XP_006718763;XP_006718764;XP_006718765 NM_001008660;NM_001206946;NM_001206947;NM_007166;XM_005274322;XM_005274323;XM_005274324;XM_005274325;XM_005274326;XM_005274327;XM_005274328;XM_005274329;XM_005274330;XM_005274331;XM_005274332;XM_005274333;XM_005274334;XM_005274335;XM_005274336;XM_005274337;XM_005274338;XM_005274340;XM_006718699;XM_006718700;XM_006718701;XM_006718702 ENSP00000377015 Q13492 TRUE cgc 1 0 0 Eukaryotes 8 Cellular processes chr11 85671731 85779822 |CLTH| XP_005274379 0 FALSE 1 30 3989 0.1290
8312 AXIN1 axin 1 16p13.3 4819 903 603816 NP_003493;NP_851393;XP_005255664;XP_005255665;XP_005255666;XP_005255667 NM_003502;NM_181050;XM_005255607;XM_005255608;XM_005255609;XM_005255610 ENSP00000262320 O15169 TRUE cgc 0 1 0 Eukaryotes 1 Cell cycle,Development,Multicellular activities,Other,Regulation of intracellular processes and metabolism,Signal transduction chr16 338125 397106 |AXIN|PPP1R49| XP_005255664 0 FALSE 2 71 23741 0.1070 44
8314 BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) 3p21.31-p21.2 4366 950 603089 NP_004647 NM_004656 ENSP00000356182;ENSP00000385450 Q92560 TRUE cgc 0 1 0 Eukaryotes 5 Cell cycle,Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism chr3 52436307 52443625 |HUCEP-13|UCHL2| NP_004647 0 FALSE 6 49 10086 0.0530
8332 HIST1H2AL histone cluster 1, H2al 6p22.1 9103 4730 602793 NP_003502 NM_003511 ENSP00000330307;ENSP00000349873;ENSP00000351589;ENSP00000352119;ENSP00000352627 NA TRUE can 0 0 19 Eukaryotes 1 -1 chr6 27775988 27776377 |H2A.i|H2A/i|H2AFI|dJ193B12.9| NP_003500 19 FALSE 1 12 487 0.3030
8334 HIST1H2AC histone cluster 1, H2ac 6p22.1 - 4733 602794 NP_003503 NM_003512 ENSP00000321389 Q93077 TRUE can 0 0 19 Eukaryotes 2 DNA/RNA metabolism and transcription chr6 26124461 26124850 |H2A/l|H2AFL|dJ221C16.4| NP_003503 19 FALSE 1 3 60 0.0000
8339 HIST1H2BG histone cluster 1, H2bg 6p21.3 - 4746 602798 NP_003509 NM_003518 ENSP00000244601;ENSP00000321744;ENSP00000348924;ENSP00000353074;ENSP00000366962 NA TRUE can 0 0 -1 Eukaryotes 1 -1 - 0 0 |H2B.1A|H2B/a|H2BFA| - -1 FALSE 1
8343 HIST1H2BF histone cluster 1, H2bf 6p22.1 11900 4752 602804 NP_003513 NM_003522 ENSP00000244601;ENSP00000321744;ENSP00000348924;ENSP00000353074;ENSP00000366962 NA TRUE can 0 0 26 Eukaryotes 1 -1 chr6 26184024 26184401 |H2B/g|H2BFG| NP_003513 26 FALSE 1 2 1 0.0000
8344 HIST1H2BE histone cluster 1, H2be 6p22.1 11901 4753 602805 NP_003514 NM_003523 ENSP00000244601;ENSP00000321744;ENSP00000348924;ENSP00000353074;ENSP00000366962 NA TRUE can 0 0 -1 Eukaryotes 2 -1 - 0 0 |H2B.h|H2B/h|H2BFH| - -1 FALSE 1
8347 HIST1H2BC histone cluster 1, H2bc 6p22.1 - 4757 602847 NP_003517 NM_003526 ENSP00000244601;ENSP00000321744;ENSP00000348924;ENSP00000353074;ENSP00000366962 NA TRUE can 0 0 26 Eukaryotes 2 Cell response to stimuli,DNA/RNA metabolism and transcription chr6 26273204 26273581 |H2B/l|H2BFL|dJ221C16.3| NP_003509 26 FALSE 2 13 379 0.0380
8348 HIST1H2BO histone cluster 1, H2bo 6p22.1 11904 4758 602808 NP_003518 NM_003527 ENSP00000303408 P23527 TRUE can 0 0 26 Eukaryotes 2 DNA/RNA metabolism and transcription chr6 27861241 27861618 |H2B.2|H2B/n|H2BFN|dJ193B12.2| NP_003518 26 FALSE 1 12 619 0.0760
8351 HIST1H3D histone cluster 1, H3d 6p22.1 - 4767 602811 NP_003521 NM_003530 ENSP00000350275;ENSP00000352252;ENSP00000444823 NA TRUE can 0 0 -1 Last Universal Common Ancestor 2 -1 - 0 0 |H3/b|H3FB| - -1 FALSE 1
8352 HIST1H3C histone cluster 1, H3c 6p22.1 11906 4768 602812 NP_003522 NM_003531 ENSP00000350275;ENSP00000352252;ENSP00000444823 NA TRUE can 0 0 -1 Last Universal Common Ancestor 2 -1 - 0 0 |H3/c|H3FC| - -1 FALSE 1
8358 HIST1H3B histone cluster 1, H3b 6p22.1 11913 4776 602819 NP_003528 NM_003537 ENSP00000350275;ENSP00000352252;ENSP00000444823 NA TRUE cgc 1 0 36 Last Universal Common Ancestor 3 -1 chr6 26045639 26046046 |H3/l|H3FL| NP_003528 36 FALSE 3 19 379 0.1580 24
8360 HIST1H4D histone cluster 1, H4d 6p22.1 11914 4782 602823 NP_003530 NM_003539 ENSP00000289352;ENSP00000343282;ENSP00000346316;ENSP00000347168;ENSP00000348258;ENSP00000350159;ENSP00000350767;ENSP00000352980;ENSP00000353624;ENSP00000358153;ENSP00000358162;ENSP00000366581;ENSP00000366974;ENSP00000367034;ENSP00000462355;ENSP00000462667 NA TRUE can 0 0 -1 Last Universal Common Ancestor 1 -1 - 0 0 |H4/b|H4FB|dJ221C16.9| - -1 FALSE 1
8365 HIST1H4H histone cluster 1, H4h 6p22.1 11919 4788 602828 NP_003534 NM_003543 ENSP00000289352;ENSP00000343282;ENSP00000346316;ENSP00000347168;ENSP00000348258;ENSP00000350159;ENSP00000350767;ENSP00000352980;ENSP00000353624;ENSP00000358153;ENSP00000358162;ENSP00000366581;ENSP00000366974;ENSP00000367034;ENSP00000462355;ENSP00000462667 NA TRUE can 0 0 -1 Last Universal Common Ancestor 5 -1 - 0 0 |H4/h|H4FH| - -1 FALSE 1
8366 HIST1H4B histone cluster 1, H4b 6p22.1 11920 4789 602829 NP_003535 NM_003544 ENSP00000289352;ENSP00000343282;ENSP00000346316;ENSP00000347168;ENSP00000348258;ENSP00000350159;ENSP00000350767;ENSP00000352980;ENSP00000353624;ENSP00000358153;ENSP00000358162;ENSP00000366581;ENSP00000366974;ENSP00000367034;ENSP00000462355;ENSP00000462667 NA TRUE can 0 0 -1 Last Universal Common Ancestor 1 -1 - 0 0 |H4/I|H4FI| - -1 FALSE 1
8405 SPOP speckle-type POZ protein 17q21.33 16004 11254 602650 NP_001007227;NP_001007228;NP_001007229;NP_001007230;NP_001007231;NP_003554;XP_005257780;XP_005257781 NM_001007226;NM_001007227;NM_001007228;NM_001007229;NM_001007230;NM_003563;XM_005257723;XM_005257724 ENSP00000240327 O43791 TRUE can 0 0 1 Eukaryotes 0 DNA/RNA metabolism and transcription,Regulation of transcription chr17 47677743 47700172 |BTBD32|TEF2| NP_001007227 1 FALSE 2 34 9231 0.0620 5
8406 SRPX sushi-repeat containing protein, X-linked Xp21.1 2175 11309 300187 NP_001164221;NP_001164222;NP_001164223;NP_006298 NM_001170750;NM_001170751;NM_001170752;NM_006307 ENSP00000367794 P78539 TRUE can 0 0 0 Metazoans 1 -1 chrX 38008967 38037598 |ETX1|HEL-S-83p|SRPX1| NP_006298 0 FALSE 1 3 35 0.3330
8439 NSMAF neutral sphingomyelinase (N-SMase) activation associated factor 8q12-q13 9117 8017 603043 NP_001138244;NP_003571 NM_001144772;NM_003580 ENSP00000411012 Q92636 TRUE can 0 0 0 Eukaryotes 4 Cellular metabolism,Signal transduction chr8 59496668 59571905 |NA| NP_001138244 0 FALSE 1 15 719 0.2000
8481 OFD1 oral-facial-digital syndrome 1 Xp22 2162 2567 300170 NP_003602;XP_005274656;XP_005274657;XP_005274658;XP_005274659;XP_005274660;XP_005274661;XP_005274662;XP_005274663;XP_005274664;XP_005274666 NM_003611;XM_005274599;XM_005274600;XM_005274601;XM_005274602;XM_005274603;XM_005274604;XM_005274605;XM_005274606;XM_005274607;XM_005274609;XR_247288 ENSP00000344314 O75665 TRUE can 0 0 1 Eukaryotes 1 -1 chrX 13753367 13787224 |71-7A|CXorf5|JBTS10|SGBS2| XP_005274656 1 FALSE 1 21 2944 0.1140 11
8493 PPM1D protein phosphatase, Mg2+/Mn2+ dependent, 1D 17q23.2 5482 9277 605100 NP_003611 NM_003620 ENSP00000306682 O15297 TRUE can 0 0 0 Eukaryotes 7 Cell cycle,Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism chr17 58677776 58740910 |WIP1| NP_003611 0 FALSE 2 23 3168 0.0590 3
8502 PKP4 plakophilin 4 2q24.1 5043 9026 604276 NP_001005476;NP_003619 NM_001005476;NM_003628 ENSP00000374409 Q99569 TRUE can 0 0 0 Eukaryotes 2 -1 chr2 159389697 159537186 |p0071| NP_003619 0 FALSE 1 24 7019 0.0540
8506 CNTNAP1 contactin associated protein 1 17q21 3825 8011 602346 NP_003623;XP_005257805;XP_006722204;XP_006722205 NM_003632;XM_005257748;XM_006722141;XM_006722142 ENSP00000264638 P78357 TRUE can 0 0 0 Eukaryotes 1 Cell motility and interactions,Regulation of intracellular processes and metabolism,Signal transduction chr17 40834848 40850925 |CASPR|CNTNAP|P190| NP_003623 0 FALSE 1 15 3808 0.2860 2
8522 GAS7 growth arrest-specific 7 17p13.1 16011 4169 603127 NP_001124303;NP_003635;NP_958836;NP_958839;XP_005256888;XP_005256889;XP_005256890;XP_005256891;XP_005256892 NM_001130831;NM_003644;NM_201432;NM_201433;XM_005256831;XM_005256832;XM_005256833;XM_005256834;XM_005256835 ENSP00000407552 O60861 TRUE cgc 1 0 0 Eukaryotes 2 Cell cycle,Development chr17 9820548 10101707 |NA| NP_958839 0 FALSE 1 25 2177 0.0670 3
8534 CHST1 carbohydrate (keratan sulfate Gal-6) sulfotransferase 1 11p11.2 - 1969 603797 NP_003645;XP_006718419;XP_006718420 NM_003654;XM_006718356;XM_006718357;XR_428858 ENSP00000309270 O43916 TRUE can 0 0 0 Metazoans 0 Cellular metabolism,Immune system response chr11 45671241 45672473 |GST-1|KS6ST|KSGal6ST|KSST| NP_003645 0 FALSE 1 2 3 0.0000
8570 KHSRP KH-type splicing regulatory protein 19p13.3 10350 6316 603445 NP_003676;XP_005259725 NM_003685;XM_005259668 ENSP00000381216 Q92945 TRUE can 0 0 1 Eukaryotes 4 Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr19 6415038 6424712 |FUBP2|KSRP| XP_005259725 1 FALSE 1 68 21419 0.1390 5
8590 OR6A2 olfactory receptor, family 6, subfamily A, member 2 11p15 9771 15301 608495 NP_003687 NM_003696 ENSP00000330384 O95222 TRUE can 0 0 0 Vertebrates 0 Cell response to stimuli,Signal transduction chr11 6815959 6816939 |I7|OR6A1|OR6A2P| NP_003687 0 TRUE 1 1
8621 CDK13 cyclin-dependent kinase 13 7p13 4496 1733 603309 NP_003709;NP_112557 NM_003718;NM_031267 ENSP00000181839 Q14004 TRUE can 0 0 0 Eukaryotes 1 Cell cycle,Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism chr7 39990241 40134576 |CDC2L|CDC2L5|hCDK13| NP_003709 0 FALSE 1 22 2663 0.1340
8626 TP63 tumor protein p63 3q28 4469 15979 603273 NP_001108450;NP_001108451;NP_001108452;NP_001108453;NP_001108454;NP_003713;XP_005247900;XP_005247901;XP_005247903 NM_001114978;NM_001114979;NM_001114980;NM_001114981;NM_001114982;NM_003722;XM_005247843;XM_005247844;XM_005247846 ENSP00000264731 Q9H3D4 TRUE can 0 0 0 Metazoans 8 Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction chr3 189349305 189612288 |B(p51A)|B(p51B)|EEC3|KET|LMS|OFC8|RHS|SHFM4|TP53CP|TP53L|TP73L|p51|p53CP|p73H|p73L| NP_003713 0 FALSE 2 124 90412 0.0620
8633 UNC5C unc-5 homolog C (C. elegans) 4q21-q23 4678 12569 603610 NP_003719;XP_005263378 NM_003728;XM_005263321 ENSP00000406022 O95185 TRUE can 0 0 0 Metazoans 1 Cell cycle,Cell motility and interactions,Development,Signal transduction chr4 96090388 96470008 |UNC5H3| XP_005263378 0 FALSE 1 4 1431 0.0000
8642 DCHS1 dachsous cadherin-related 1 11p15.4 4341 13681 603057 NP_003728;XP_005253264 NM_003737;NM_024542;XM_005253207 ENSP00000299441 Q96JQ0 TRUE can 0 0 0 Last Universal Common Ancestor 0 Cell motility and interactions chr11 6643013 6685320 |CDH25|CDHR6|FIB1|PCDH16|VMLDS1| XP_005253264 0 FALSE 1 1 0 0.0000
8648 NCOA1 nuclear receptor coactivator 1 2p23 4070 7668 602691 NP_003734;NP_671756;NP_671766;XP_005264682;XP_005264683;XP_005264684;XP_005264685;XP_006712189 NM_003743;NM_147223;NM_147233;XM_005264625;XM_005264626;XM_005264627;XM_005264628;XM_006712126 ENSP00000320940 Q15788 TRUE cgc 1 0 0 Eukaryotes 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction chr2 24881547 24991257 |F-SRC-1|KAT13A|RIP160|bHLHe74| NP_003734 0 FALSE 1 84 24782 0.1590 13
8651 SOCS1 suppressor of cytokine signaling 1 16p13.13 4669 19383 603597 NP_003736 NM_003745 ENSP00000329418 O15524 TRUE cgc 0 1 0 Vertebrates 7 Cell cycle,Cellular metabolism,Cellular processes,Development,Regulation of intracellular processes and metabolism,Signal transduction chr16 11348703 11349335 |CIS1|CISH1|JAB|SOCS-1|SSI-1|SSI1|TIP3| NP_003736 0 FALSE 1 63 49964 0.1580 3
8661 EIF3A eukaryotic translation initiation factor 3, subunit A 10q26 - 3271 602039 NP_003741 NM_003750 ENSP00000363559 Q14152 TRUE can 0 0 0 Last Universal Common Ancestor 3 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr10 120795554 120840188 |EIF3|EIF3S10|P167|TIF32|eIF3-p170|eIF3-theta|p185| NP_003741 0 FALSE 1 100 30552 0.1210 16
8726 EED embryonic ectoderm development 11q14.2-q22.3 9343 3188 605984 NP_003788;NP_694536;XP_005274430;XP_006718793;XP_006718794 NM_003797;NM_152991;XM_005274373;XM_006718730;XM_006718731;XR_247215 ENSP00000263360 O75530 TRUE can 0 0 1 Eukaryotes 3 -1 chr11 85956272 85989564 |HEED|WAIT1| NP_003788 1 FALSE 2 451 405115 0.0430 18
8737 RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1 6p25.2 4583 10019 603453 NP_003795;XP_005249514;XP_005249515;XP_006715299;XP_006715300 NM_003804;XM_005249457;XM_005249458;XM_006715236;XM_006715237 ENSP00000259808 Q13546 TRUE can 0 0 0 Eukaryotes 0 Cell cycle,Cellular metabolism,Cellular processes,Development,Regulation of intracellular processes and metabolism,Signal transduction chr6 3068446 3113570 |NA| XP_005249514 0 FALSE 1 88 21732 0.1560 22
8743 TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 3q26 4670 11925 603598 NP_001177871;NP_001177872;NP_003801 NM_001190942;NM_001190943;NM_003810;NR_033994 ENSP00000241261 P50591 TRUE can 0 0 0 Metazoans 3 Cell cycle,Development,Regulation of intracellular processes and metabolism,Signal transduction chr3 172224285 172241174 |APO2L|Apo-2L|CD253|TL2|TRAIL| NP_003801 0 FALSE 1 18 2867 0.2220 8
8756 ADAM7 ADAM metallopeptidase domain 7 8p21.2 7391 214 607310 NP_003808;XP_005273725;XP_005273726;XP_005273727;XP_005273728;XP_005273729;XP_005273730 NM_003817;XM_005273668;XM_005273669;XM_005273670;XM_005273671;XM_005273672;XM_005273673 ENSP00000175238 Q9H2U9 TRUE can 0 0 0 Eukaryotes 0 Cellular metabolism chr8 24298622 24366136 |ADAM 7|ADAM-7|EAPI|GP-83|GP83| XP_005273725 0 FALSE 1
8764 TNFRSF14 tumor necrosis factor receptor superfamily, member 14 1p36.32 4122 11912 602746 NP_003811;XP_006711081;XP_006711082;XP_006711083;XP_006725009;XP_006725010;XP_006725011 NM_003820;XM_006711018;XM_006711019;XM_006711020;XM_006724946;XM_006724947;XM_006724948;XR_426638;XR_430632 ENSP00000347948 Q92956 TRUE cgc 0 1 0 Metazoans 0 Cell cycle,Signal transduction chr1 2488104 2494709 |ATAR|CD270|HVEA|HVEM|LIGHTR| NP_003811 0 FALSE 1 77 69305 0.0290 4
8797 TNFRSF10A tumor necrosis factor receptor superfamily, member 10a 8p21 - 11904 603611 NP_003835 NM_003844 ENSP00000221132 O00220 TRUE can 0 0 0 Vertebrates 3 Cell cycle,Development,Regulation of intracellular processes and metabolism,Signal transduction chr8 23049210 23082574 |APO2|CD261|TRAILR-1|TRAILR1| NP_003835 0 FALSE 1 25 3733 0.1670 10
8805 TRIM24 tripartite motif containing 24 7q32-q34 4556 11812 603406 NP_003843;NP_056989 NM_003852;NM_015905 ENSP00000340507 O15164 TRUE cgc 1 0 0 Eukaryotes 4 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr7 138145294 138269693 |PTC6|RNF82|TF1A|TIF1|TIF1A|TIF1ALPHA|hTIF1| NP_056989 0 FALSE 1 53 8543 0.1300 4
8807 IL18RAP interleukin 18 receptor accessory protein 2q12 5147 5989 604509 NP_003844;XP_005264091 NM_003853;XM_005264034 ENSP00000264260 O95256 TRUE can 0 0 0 Vertebrates 0 Immune system response,Signal transduction chr2 103039738 103068638 |ACPL|CD218b|CDw218b|IL-18R-beta|IL-18RAcP|IL-18Rbeta|IL-1R-7|IL-1R7|IL-1RAcPL|IL18RB| NP_003844 0 FALSE 1 3 2164 0.0000
8833 GMPS guanine monphosphate synthase 3q24 10927 4378 600358 NP_003866 NM_003875 ENSP00000419851 P49915 TRUE cgc 1 0 0 Last Universal Common Ancestor 1 Cellular metabolism,DNA/RNA metabolism and transcription chr3 155611307 155655478 |NA| NP_003866 0 FALSE 1 28 8117 0.1060
8842 PROM1 prominin 1 4p15.32 5079 9454 604365 NP_001139319;NP_001139320;NP_001139321;NP_001139322;NP_001139323;NP_001139324;NP_006008;XP_005248252;XP_005248253;XP_006714036;XP_006714037 NM_001145847;NM_001145848;NM_001145849;NM_001145850;NM_001145851;NM_001145852;NM_006017;XM_005248195;XM_005248196;XM_006713973;XM_006713974 ENSP00000415481 O43490 TRUE can 0 0 0 Metazoans 1 Cell response to stimuli chr4 15981020 16077529 |AC133|CD133|CORD12|PROML1|RP41|STGD4| NP_006008 0 FALSE 1 3 630 0.0000
8847 DLEU2 deleted in lymphocytic leukemia 2 (non-protein coding) 13q14.3 - 13748 605766 - NR_002612 - NA TRUE can 0 0 -1 - 1 -1 - 0 0 |1B4|BCMSUN|DLB2|LINC00022|MIR15AHG|NCRNA00022|RFP2OS|TRIM13OS| - -1 FALSE 1
8848 TSC22D1 TSC22 domain family, member 1 13q14 7414 16826 607715 NP_001230726;NP_001230727;NP_001230728;NP_006013;NP_904358;XP_005266639;XP_005266640;XP_006719950 NM_001243797;NM_001243798;NM_001243799;NM_006022;NM_183422;XM_005266582;XM_005266583;XM_006719887 ENSP00000397435 Q15714 TRUE can 0 0 0 Metazoans 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr13 45008765 45150210 |Ptg-2|TGFB1I4|TSC22| NP_904358 0 FALSE 1 162 112688 0.0200 1
8859 STK19 serine/threonine kinase 19 6p21.3 7281 11398 604977 NP_004188;NP_115830 NM_004197;NM_032454;NR_026717 ENSP00000220676;ENSP00000391798;ENSP00000413766 P49842 TRUE can 0 0 -1 Eukaryotes 0 Cellular metabolism,Cellular processes - 0 0 |D6S60|D6S60E|G11|HLA-RP1| - -1 FALSE 1
8861 LDB1 LIM domain binding 1 10q24-q25 9144 6532 603451 NP_001106878;NP_003884;XP_005270319 NM_001113407;NM_003893;XM_005270262 ENSP00000306772;ENSP00000392466 Q86U70 TRUE can 0 0 0 Metazoans 0 Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Regulation of transcription chr10 103867853 103871294 |CLIM2|NLI| NP_001106878 0 FALSE 1 34 26675 0.0770 7
8877 SPHK1 sphingosine kinase 1 17q25.2 4768 11240 603730 NP_001136073;NP_001136074;NP_068807;NP_892010;XP_005257823 NM_001142601;NM_001142602;NM_021972;NM_182965;XM_005257766 ENSP00000313681 Q9NYA1 TRUE can 0 0 0 Last Universal Common Ancestor 3 Cell cycle,Cell motility and interactions,Cellular metabolism,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Signal transduction chr17 74381187 74383664 |SPHK| NP_892010 0 FALSE 1 14 3502 0.0990 1
8880 FUBP1 far upstream element (FUSE) binding protein 1 1p31.1 10349 4004 603444 NP_003893;XP_005271366;XP_006711084;XP_006711085 NM_003902;XM_005271309;XM_006711021;XM_006711022 ENSP00000359804 Q96AE4 TRUE cgc 0 1 0 Eukaryotes 6 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr1 78414840 78444688 |FUBP| XP_005271366 0 FALSE 2 62 22521 0.0990 1
8912 CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit 16p13.3 7442 1395 607904 NP_001005407;NP_066921;XP_005255709;XP_006721026;XP_006721027;XP_006721028;XP_006721029;XP_006721030;XP_006721031;XP_006721032 NM_001005407;NM_021098;XM_005255652;XM_006720963;XM_006720964;XM_006720965;XM_006720966;XM_006720967;XM_006720968;XM_006720969 ENSP00000334198 O95180 TRUE can 0 0 0 Last Universal Common Ancestor 0 Cell cycle,Cellular processes,Development,Multicellular activities chr16 1203738 1270991 |CACNA1HB|Cav3.2|ECA6|EIG6| NP_066921 0 FALSE 1 6 162 0.0000
8915 BCL10 B-cell CLL/lymphoma 10 1p22 4625 989 603517 NP_003912;XP_005271368 NM_003921;XM_005271311 ENSP00000271015 O95999 TRUE cgc 1 0 0 Metazoans 3 Cell cycle,Cell response to stimuli,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Immune system response,Multicellular activities,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction chr1 85733313 85742035 |CARMEN|CIPER|CLAP|c-E10|mE10| NP_003912 0 FALSE 1 63 38619 0.0810 18
8924 HERC2 HECT and RLD domain containing E3 ubiquitin protein ligase 2 15q13 6905 4868 605837 NP_004658;XP_005268333;XP_005268334;XP_006720789;XP_006720790 NM_004667;XM_005268276;XM_005268277;XM_006720726;XM_006720727 ENSP00000458767 O95714 TRUE can 0 0 0 Last Universal Common Ancestor 3 Cellular metabolism,Cellular processes chr15 28356912 28566579 |D15F37S1|MRT38|jdf2|p528| NP_004658 0 FALSE 1 44 7968 0.0870 1
8925 HERC1 HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 15q22 6894 4867 605109 NP_003913;XP_005254799;XP_005254800;XP_005254803;XP_005254804;XP_006720791 NM_003922;XM_005254742;XM_005254743;XM_005254746;XM_005254747;XM_006720728;XR_243129 ENSP00000390158 Q15751 TRUE can 0 0 0 Last Universal Common Ancestor 0 Cellular metabolism,Cellular processes chr15 63901283 64067822 |p532|p619| NP_003913 0 FALSE 1 18 940 0.0720
8929 PHOX2B paired-like homeobox 2b 4p12 9157 9143 603851 NP_003915 NM_003924 ENSP00000226382 Q99453 TRUE cgc 0 1 0 - 0 Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription chr4 41747827 41750627 |NBLST2|NBPhox|PMX2B| NP_003915 0 FALSE 1 1 0 0.0000
8969 HIST1H2AG histone cluster 1, H2ag 6p22.1 - 4737 615012 NP_066408 NM_021064 ENSP00000330307;ENSP00000349873;ENSP00000351589;ENSP00000352119;ENSP00000352627 B2R5B3 TRUE can 0 0 -1 Eukaryotes 2 DNA/RNA metabolism and transcription - 0 0 |H2A.1b|H2A/p|H2AFP|H2AG| - -1 FALSE 1
8997 KALRN kalirin, RhoGEF kinase 3q21.2 6859 4814 604605 NP_001019831;NP_003938;NP_008995;XP_006713873;XP_006713874;XP_006713875;XP_006713876;XP_006713877;XP_006713878;XP_006713879;XP_006713880 NM_001024660;NM_003947;NM_007064;NR_028136;XM_006713810;XM_006713811;XM_006713812;XM_006713813;XM_006713814;XM_006713815;XM_006713816;XM_006713817 ENSP00000240874;ENSP00000262450;ENSP00000327716;ENSP00000362330 O60229 TRUE can 0 0 0 Eukaryotes 1 Cellular metabolism,Cellular processes,Development,Signal transduction chr3 123813685 124438314 |ARHGEF24|CHDS5|DUET|DUO|HAPIP| NP_001019831 0 FALSE 1 20 3188 0.0370 4
9037 SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A 5p15.2 10219 10736 609297 NP_003957;XP_006714569;XP_006714570;XP_006714571 NM_003966;XM_006714506;XM_006714507;XM_006714508 ENSP00000371936 Q13591 TRUE can 0 0 0 Opisthokonts 1 Development chr5 9043012 9380058 |semF| NP_003957 0 FALSE 1 1
9053 MAP7 microtubule-associated protein 7 6q23.3 4982 6869 604108 NP_001185537;NP_001185538;NP_001185540;NP_001185543;NP_001185544;NP_001185545;NP_001185546;NP_001185547;NP_001185548;NP_003971;XP_005267266;XP_006715661;XP_006715662;XP_006715663;XP_006715664 NM_001198608;NM_001198609;NM_001198611;NM_001198614;NM_001198615;NM_001198616;NM_001198617;NM_001198618;NM_001198619;NM_003980;XM_005267209;XM_006715598;XM_006715599;XM_006715600;XM_006715601 ENSP00000414712 Q14244 TRUE can 0 0 0 Vertebrates 7 Cellular processes,Development chr6 136666995 136847102 |E-MAP-115|EMAP115| NP_001185538 0 FALSE 1 12 887 0.0610
9096 TBX18 T-box 18 6q14-q15 - 11595 604613 NP_001073977;XP_006715665 NM_001080508;XM_006715602 ENSP00000358677 O95935 TRUE can 0 0 0 Metazoans 0 Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Other,Regulation of intracellular processes and metabolism,Regulation of transcription chr6 85446406 85473899 |NA| NP_001073977 0 FALSE 1
9098 USP6 ubiquitin specific peptidase 6 17p13 6827 12629 604334 NP_004496;XP_005256902 NM_004505;NM_005152;XM_005256845 ENSP00000250066 P35125 TRUE cgc 1 0 0 Eukaryotes 1 Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism,Signal transduction chr17 5033663 5076270 |HRP1|TRE2|Tre-2|USP6-short| NP_004496 0 FALSE 1 12 4892 0.0300
9122 SLC16A4 solute carrier family 16, member 4 1p13.3 4855 10925 603878 NP_001188475;NP_001188476;NP_001188477;NP_001188478;NP_004687;XP_005271374;XP_005271375;XP_006711096 NM_001201546;NM_001201547;NM_001201548;NM_001201549;NM_004696;XM_005271317;XM_005271318;XM_006711033;XR_246304;XR_426639 ENSP00000358794 O15374 TRUE can 0 0 0 Eukaryotes 2 Cellular processes chr1 110906391 110931945 |NA| NP_004687 0 FALSE 1 2 106 0.0000
9125 RQCD1 RCD1 required for cell differentiation1 homolog (S. pombe) 2q35 8828 10445 612054 NP_001258563;NP_001258564;NP_005435;XP_005246999;XP_005247000;XP_006712895 NM_001271634;NM_001271635;NM_005444;NR_073390;XM_005246942;XM_005246943;XM_006712832 ENSP00000273064 Q92600 TRUE can 0 0 0 Eukaryotes 2 Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription chr2 219445284 219458996 |CNOT9|CT129|RCD-1| NP_001258563 0 FALSE 1 20 3085 0.2210
9126 SMC3 structural maintenance of chromosomes 3 10q25 5829 2468 606062 NP_005436 NM_005445 ENSP00000354720 Q9UQE7 TRUE can 0 0 0 Last Universal Common Ancestor 3 Cell cycle,Cellular processes,DNA/RNA metabolism and transcription,Signal transduction chr10 112328696 112364057 |CDLS3|CSPG6|SMC3L1| NP_005436 0 FALSE 1 89 62126 0.0940 34
9133 CCNB2 cyclin B2 15q22.2 4131 1580 602755 NP_004692 NM_004701 ENSP00000288207 O95067 TRUE can 0 0 1 Eukaryotes 0 Cell cycle chr15 59399521 59417073 |HsT17299| NP_004692 1 FALSE 1 10 124 0.3560 4
9135 RABEP1 rabaptin, RAB GTPase binding effector protein 1 17p13.2 4684 17677 603616 NP_001077054;NP_004694 NM_001083585;NM_004703 ENSP00000262477 Q15276 TRUE cgc 1 0 0 Metazoans 1 Cell cycle,Cellular processes chr17 5211982 5286515 |RAB5EP|RABPT5| NP_004694 0 FALSE 1 40 8447 0.0670 2
9159 PCSK7 proprotein convertase subtilisin/kexin type 7 11q23-q24 - 8748 604872 NP_004707;XP_006719001;XP_006719002;XP_006719003 NM_004716;XM_006718938;XM_006718939;XM_006718940;XR_428984;XR_428985 ENSP00000325917 Q16549 TRUE cgc 1 0 0 Last Universal Common Ancestor 0 Cellular metabolism,Cellular processes chr11 117076716 117100560 |LPC|PC7|PC8|SPC7| NP_004707 0 FALSE 1 7 8163 0.3810
9172 MYOM2 myomesin 2 8p23.3 4619 7614 603509 NP_003961;XP_006716300 NM_003970;XM_006716237 ENSP00000262113;ENSP00000454232 P54296 TRUE can 0 0 0 Vertebrates 0 Multicellular activities chr8 1998881 2092902 |TTNAP| NP_003961 0 FALSE 1 16 848 0.1330
9175 MAP3K13 mitogen-activated protein kinase kinase kinase 13 3q27 5372 6852 604915 NP_001229243;NP_001229246;NP_004712 NM_001242314;NM_001242317;NM_004721;NR_038322 ENSP00000265026 O43283 TRUE can 0 0 0 Last Universal Common Ancestor 0 Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction chr3 185146370 185200241 |LZK|MEKK13|MLK| NP_001229243 0 FALSE 1 6 89 0.2000
9201 DCLK1 doublecortin-like kinase 1 13q13 9202 2700 604742 NP_001182344;NP_001182345;NP_001182359;NP_004725;XP_005266649;XP_006719956 NM_001195415;NM_001195416;NM_001195430;NM_004734;XM_005266592;XM_006719893 ENSP00000255448 O15075 TRUE can 0 0 0 Eukaryotes 0 Cellular metabolism,Cellular processes,Development,Signal transduction chr13 36348675 36700274 |CLICK1|DCAMKL1|DCDC3A|DCLK| XP_005266649 0 FALSE 1 3 276 0.0000
9203 ZMYM3 zinc finger, MYM-type 3 Xq13.1 2088 13054 300061 NP_001164633;NP_001164634;NP_005087;NP_963893;XP_005262366;XP_005262367;XP_006724778 NM_001171162;NM_001171163;NM_005096;NM_201599;XM_005262309;XM_005262310;XM_006724715 ENSP00000322845 Q14202 TRUE can 0 0 0 Metazoans 0 -1 chrX 70460769 70473105 |DXS6673E|XFIM|ZNF198L2|ZNF261| NP_005087 0 FALSE 2 17 3583 0.2350 4
9294 S1PR2 sphingosine-1-phosphate receptor 2 19p13.2 - 3169 605111 NP_004221;XP_006722999 NM_004230;XM_006722936 ENSP00000466933 O95136 TRUE can 0 0 0 Vertebrates 0 Cell cycle,Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism,Signal transduction chr19 10334523 10335581 |AGR16|EDG-5|EDG5|Gpcr13|H218|LPB2|S1P2| NP_004221 0 FALSE 1 5 124 0.1000 2
9314 KLF4 Kruppel-like factor 4 (gut) 9q31 - 6348 602253 NP_004226;XP_005252362 NM_004235;XM_005252305 ENSP00000363804 O43474 TRUE cgc 1 0 0 Eukaryotes 9 Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription chr9 110248035 110251333 |EZF|GKLF| XP_005252362 0 FALSE 1 25 3041 0.3000 1
9321 TRIP11 thyroid hormone receptor interactor 11 14q31-q32 5143 12305 604505 NP_004230;XP_005268270;XP_005268271;XP_005268272;XP_006720384 NM_004239;XM_005268213;XM_005268214;XM_005268215;XM_006720321 ENSP00000267622 Q15643 TRUE cgc 1 0 0 Metazoans 3 Cellular metabolism,DNA/RNA metabolism and transcription chr14 92436020 92506029 |ACG1A|CEV14|GMAP-210|TRIP-11|TRIP230| NP_004230 0 FALSE 1 11 521 0.1270
9353 SLIT2 slit homolog 2 (Drosophila) 4p15.2 4776 11086 603746 NP_001276064;NP_001276065;NP_004778;XP_005248268;XP_005248271;XP_006714049 NM_001289135;NM_001289136;NM_004787;XM_005248211;XM_005248214;XM_006713986 ENSP00000422591 O94813 TRUE can 0 0 0 Last Universal Common Ancestor 0 Cell cycle,Cell motility and interactions,Cell response to stimuli,Development,Immune system response,Multicellular activities,Regulation of intracellular processes and metabolism,Signal transduction chr4 20255439 20620629 |SLIL3|Slit-2| XP_005248268 0 FALSE 1 8 1373 0.1790 5
9368 SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 17q25.1 5406 11075 604990 NP_004243 NM_004252 ENSP00000262613 O14745 TRUE can 0 0 0 Metazoans 2 Regulation of intracellular processes and metabolism,Signal transduction chr17 72744986 72764792 |EBP50|NHERF|NHERF-1|NHERF1|NPHLOP2| NP_004243 0 FALSE 1 94 141205 0.0440 5
9369 NRXN3 neurexin 3 14q31 8989 8010 600567 NP_001098720;NP_001258949;NP_004787;NP_620426;XP_005268275;XP_006720385;XP_006720386 NM_001105250;NM_001272020;NM_004796;NM_138970;NR_073546;NR_073547;XM_005268218;XM_006720322;XM_006720323 ENSP00000338349 Q9Y4C0 TRUE can 0 0 0 Metazoans 1 Cell cycle,Cell motility and interactions,Development chr14 78709437 80328304 |C14orf60| XP_005268275 0 TRUE 1 6 785 0.0000
9378 NRXN1 neurexin 1 2p16.3 11858 8008 600565 NP_001129131;NP_004792;NP_620072;XP_005264699;XP_005264700;XP_006712196;XP_006712197;XP_006712198;XP_006712199;XP_006712200;XP_006712201;XP_006712202;XP_006712203;XP_006712204;XP_006712205;XP_006712206;XP_006712207 NM_001135659;NM_004801;NM_138735;XM_005264642;XM_005264643;XM_006712133;XM_006712134;XM_006712135;XM_006712136;XM_006712137;XM_006712138;XM_006712139;XM_006712140;XM_006712141;XM_006712142;XM_006712143;XM_006712144 ENSP00000385142 Q9ULB1 TRUE can 0 0 0 Metazoans 0 Cell cycle,Cell motility and interactions,Development chr2 50149085 51255411 |Hs.22998|PTHSL2|SCZD17| NP_001129131 0 TRUE 2 28 48102 0.0080 1
9379 NRXN2 neurexin 2 11q13 11859 8009 600566 NP_055895;NP_620060;NP_620063;XP_005274457;XP_005274458;XP_005274459;XP_005274463;XP_006718805;XP_006718806;XP_006718807;XP_006718808;XP_006718809;XP_006718810;XP_006718811;XP_006718812 NM_015080;NM_138732;NM_138734;XM_005274400;XM_005274401;XM_005274402;XM_005274406;XM_006718742;XM_006718743;XM_006718744;XM_006718745;XM_006718746;XM_006718747;XM_006718748;XM_006718749;XR_428930;XR_428931 ENSP00000265459 Q9P2S2 TRUE can 0 0 0 Metazoans 0 Cellular processes,Development,Multicellular activities,Signal transduction chr11 64374671 64481171 |NA| NP_055895 0 FALSE 1 9 741 0.0280
9401 RECQL4 RecQ protein-like 4 8q24.3 4805 9949 603780 NP_004251 NM_004260 - O94761 TRUE cgc 0 1 0 - 1 Cell cycle,Cellular processes,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism chr8 145736817 145743168 |RECQ4| NP_004251 0 FALSE 1 12 804 0.1520 1
9407 TMPRSS11D transmembrane protease, serine 11D 4q13.2 5642 24059 605369 NP_004253;XP_005265767 NM_004262;XM_005265710 ENSP00000283916 O60235 TRUE can 0 0 0 Last Universal Common Ancestor 1 Cellular metabolism chr4 68688058 68725398 |HAT| NP_004253 0 FALSE 1
9425 CDYL chromodomain protein, Y-like 6p25.1 4803 1811 603778 NP_001137442;NP_001137443;NP_004815;XP_006715335 NM_001143970;NM_001143971;NM_004824;NM_170752;NR_026590;XM_006715272 ENSP00000380718 Q9Y232 TRUE can 0 0 1 Last Universal Common Ancestor 0 Cellular metabolism,DNA/RNA metabolism and transcription,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Regulation of transcription chr6 4891947 4954287 |CDYL1| NP_004815 1 FALSE 1 20 2200 0.3160 2
9444 QKI QKI, KH domain containing, RNA binding 6q26 6691 21100 609590 NP_006766;NP_996735;NP_996736;NP_996737;XP_005267281 NM_006775;NM_206853;NM_206854;NM_206855;XM_005267224;XR_245557;XR_427977;XR_427978 ENSP00000355094 Q96PU8 TRUE can 0 0 0 Eukaryotes 3 Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr6 163836226 163987826 |Hqk|QK|QK1|QK3|hqkI| NP_006766 0 FALSE 1 56 47340 0.1220
9472 AKAP6 A kinase (PRKA) anchor protein 6 14q12 - 376 604691 NP_004265;XP_005268276 NM_004274;XM_005268219 ENSP00000280979 Q13023 TRUE can 0 0 0 Vertebrates 0 Cellular processes chr14 32902700 33293976 |ADAP100|ADAP6|AKAP100|PRKA6|mAKAP| XP_005268276 0 FALSE 2 17 2229 0.2280 1
9500 MAGED1 melanoma antigen family D, 1 Xp11.23 2202 6813 300224 NP_001005332;NP_001005333;NP_008917 NM_001005332;NM_001005333;NM_006986 ENSP00000364847;ENSP00000472440 Q9Y5V3 TRUE can 0 0 0 Eukaryotes 0 Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chrX 51637401 51645023 |DLXIN-1|NRAGE| NP_001005333 0 FALSE 1 104 73794 0.0400
9542 NRG2 neuregulin 2 5q23-q33 - 7998 603818 NP_001171864;NP_004874;NP_053584;NP_053585;NP_053586;XP_005268590;XP_006714871;XP_006714872;XP_006714873 NM_001184935;NM_004883;NM_013981;NM_013982;NM_013983;NM_013984;NM_013985;XM_005268533;XM_006714808;XM_006714809;XM_006714810 ENSP00000354910 O14511 TRUE can 0 0 0 Metazoans 0 Signal transduction chr5 139227505 139422654 |DON1|HRG2|NTAK| NP_053585 0 FALSE 1 2 0 1.0000 12
9577 BRE brain and reproductive organ-expressed (TNFRSF1A modulator) 2p23.2 8498 1106 610497 NP_001248769;NP_004890;NP_954661;NP_954662;NP_954663;NP_954664 NM_001261840;NM_004899;NM_199191;NM_199192;NM_199193;NM_199194 ENSP00000343412 Q9NXR7 TRUE can 0 0 0 Eukaryotes 3 Cell cycle,Development,Regulation of intracellular processes and metabolism,Signal transduction chr2 28117424 28550297 |BRCC4|BRCC45| NP_004890 0 FALSE 1 39 7521 0.1610 1
9578 CDC42BPB CDC42 binding protein kinase beta (DMPK-like) 14q32.3 8516 1738 614062 NP_006026;XP_005268284;XP_005268285;XP_005268286;XP_005268287 NM_006035;XM_005268227;XM_005268228;XM_005268229;XM_005268230 ENSP00000355237 Q9Y5S2 TRUE can 0 0 0 Last Universal Common Ancestor 3 Cellular metabolism,Cellular processes,Development,Signal transduction chr14 103400052 103523510 |MRCKB| XP_005268284 0 FALSE 1 14 608 0.0330
9601 PDIA4 protein disulfide isomerase family A, member 4 7q35 6501 30167 - NP_004902;XP_006716248 NM_004911;XM_006716185 ENSP00000286091 P13667 TRUE can 0 0 0 Last Universal Common Ancestor 1 Cellular processes,Regulation of intracellular processes and metabolism chr7 148700889 148725500 |ERP70|ERP72|ERp-72| NP_004902 0 FALSE 1 57 15713 0.1510 3
9603 NFE2L3 nuclear factor, erythroid 2-like 3 7p15.2 9162 7783 604135 NP_004280 NM_004289 ENSP00000056233 Q9Y4A8 TRUE can 0 0 2 Vertebrates 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr7 26192119 26225400 |NRF3| NP_004280 2 FALSE 2 9 326 0.5000
9611 NCOR1 nuclear receptor corepressor 1 17p11.2 2911 7672 600849 NP_001177367;NP_001177369;NP_006302;XP_005256923;XP_005256924;XP_005256925;XP_005256928;XP_005256929;XP_005256930;XP_005256931;XP_005256932;XP_006721664;XP_006721665;XP_006721666;XP_006721667;XP_006721668 NM_001190438;NM_001190440;NM_006311;XM_005256866;XM_005256867;XM_005256868;XM_005256871;XM_005256872;XM_005256873;XM_005256874;XM_005256875;XM_006721601;XM_006721602;XM_006721603;XM_006721604;XM_006721605 ENSP00000268712 O75376 TRUE can 0 0 0 Eukaryotes 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr17 15935613 16097883 |N-CoR|N-CoR1|PPP1R109|hN-CoR| XP_005256923 0 FALSE 4 148 60905 0.1010 24
9612 NCOR2 nuclear receptor corepressor 2 12q24 2910 7673 600848 NP_001070729;NP_001193583;NP_006303 NM_001077261;NM_001206654;NM_006312 ENSP00000384018 Q9Y618 TRUE can 0 0 0 Eukaryotes 5 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr12 124809951 124979797 |N-CoR2|SMAP270|SMRT|SMRTE|SMRTE-tau| NP_006303 0 FALSE 1 108 26024 0.1480 22
9651 PLCH2 phospholipase C, eta 2 1p36.32 - 29037 612836 NP_055453;XP_006711117;XP_006711118;XP_006725012;XP_006725013;XP_006725014 NM_014638;XM_006711054;XM_006711055;XM_006724949;XM_006724950;XM_006724951 ENSP00000367747 O75038 TRUE can 0 0 0 Eukaryotes 1 Cellular metabolism,Signal transduction chr1 2408028 2436649 |PLC-eta2|PLCL4|PLCeta2| NP_055453 0 FALSE 1
9659 PDE4DIP phosphodiesterase 4D interacting protein 1q12 10482 15580 608117 NP_001002810;NP_001002811;NP_001002812;NP_001182189;NP_001182190;NP_001185761;NP_001185763;NP_055459;NP_071754;XP_005273038;XP_005277499;XP_005277500;XP_005277503;XP_006711705;XP_006711706;XP_006711707;XP_006711708;XP_006711709;XP_006711710;XP_006711711;XP_006711712;XP_006711713;XP_006711714;XP_006711715;XP_006711716;XP_006711717;XP_006711718;XP_006711719 NM_001002810;NM_001002811;NM_001002812;NM_001195260;NM_001195261;NM_001198832;NM_001198834;NM_014644;NM_022359;XM_005272981;XM_005277442;XM_005277443;XM_005277446;XM_006711642;XM_006711643;XM_006711644;XM_006711645;XM_006711646;XM_006711647;XM_006711648;XM_006711649;XM_006711650;XM_006711651;XM_006711652;XM_006711653;XM_006711654;XM_006711655;XM_006711656 ENSP00000462316 Q5VU43 TRUE cgc 1 0 0 Eukaryotes 0 Cellular processes chr1 144852357 144931708 |CMYA2|MMGL| XP_005277499 0 FALSE 1 82 52639 0.0340
9699 RIMS2 regulating synaptic membrane exocytosis 2 8q22.3 - 17283 606630 NP_001093587;NP_001269810;NP_001269811;NP_055492;XP_005251163;XP_005251164;XP_005251165;XP_006716753;XP_006716754;XP_006716755;XP_006716756;XP_006716757;XP_006716758;XP_006716759;XP_006716760;XP_006716761;XP_006716762 NM_001100117;NM_001282881;NM_001282882;NM_014677;XM_005251106;XM_005251107;XM_005251108;XM_006716690;XM_006716691;XM_006716692;XM_006716693;XM_006716694;XM_006716695;XM_006716696;XM_006716697;XM_006716698;XM_006716699 ENSP00000384892 Q9UQ26 TRUE can 0 0 0 Metazoans 2 Cellular processes chr8 104513115 105264045 |OBOE|RAB3IP3|RIM2| XP_005251163 0 FALSE 4 16 4934 0.0420
9700 ESPL1 extra spindle pole bodies homolog 1 (S. cerevisiae) 12q 6825 16856 604143 NP_036423;XP_006719768 NM_012291;XM_006719705 ENSP00000257934 Q14674 TRUE can 0 0 0 Eukaryotes 4 Cell cycle,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism chr12 53662551 53687255 |SEPA| NP_036423 0 FALSE 1 14 1394 0.1430 4
9701 PPP6R2 protein phosphatase 6, regulatory subunit 2 22q13.33 11102 19253 610877 NP_001229827;NP_001229828;NP_001229829;NP_055493;XP_005262013;XP_005262014;XP_005262015;XP_005262016;XP_005262017;XP_006724491;XP_006724492;XP_006724493;XP_006724494;XP_006724495;XP_006724496;XP_006724497;XP_006724498 NM_001242898;NM_001242899;NM_001242900;NM_014678;XM_005261956;XM_005261957;XM_005261958;XM_005261959;XM_005261960;XM_006724428;XM_006724429;XM_006724430;XM_006724431;XM_006724432;XM_006724433;XM_006724434;XM_006724435 ENSP00000379090 O75170 TRUE can 0 0 0 Eukaryotes 4 -1 chr22 50831835 50882673 |KIAA0685|PP6R2|SAPS2| XP_005262013 0 FALSE 1 30 6210 0.1610 3
9709 HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 16q13 7456 13744 608070 NP_001010989;NP_001259032;NP_055500;XP_006721415 NM_001010989;NM_001010990;NM_001272103;NM_014685;XM_006721352 ENSP00000409555 Q15011 TRUE cgc 1 0 0 Metazoans 4 Cell response to stimuli,Cellular metabolism,Cellular processes chr16 56966157 56977199 |HERP|Mif1|SUP| NP_055500 0 FALSE 1 29 20317 0.1450 1
9723 SEMA3E sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E 7q21.11 11545 10727 608166 NP_001171600;NP_036563;XP_006716250 NM_001178129;NM_012431;XM_006716187 ENSP00000303212 O15041 TRUE can 0 0 0 Vertebrates 0 Development chr7 82996905 83277858 |M-SEMAH|M-SemaK|SEMAH|coll-5| NP_036563 0 FALSE 2 1 0 0.0000 1
9730 VPRBP Vpr (HIV-1) binding protein 3p21.2 11674 30911 - NP_001165375;NP_055518;XP_005276808;XP_005276809;XP_005276810;XP_005276811;XP_005276812;XP_006713489;XP_006713490;XP_006713491 NM_001171904;NM_014703;XM_005276751;XM_005276752;XM_005276753;XM_005276754;XM_005276755;XM_006713426;XM_006713427;XM_006713428;XR_254197;XR_254198;XR_427298;XR_427299 ENSP00000393183;ENSP00000454540 Q9Y4B6 TRUE can 0 0 0 Eukaryotes 0 -1 chr3 51436203 51517844 |DCAF1| NP_055518 0 FALSE 1 56 7778 0.1770 1
9732 DOCK4 dedicator of cytokinesis 4 7q31.1 7407 19192 607679 NP_055520;XP_006716251;XP_006716252 NM_014705;XM_006716188;XM_006716189 ENSP00000404179 Q8N1I0 TRUE can 0 0 0 Eukaryotes 2 -1 chr7 111368333 111846193 |NA| NP_055520 0 FALSE 1 10 345 0.2670
9734 HDAC9 histone deacetylase 9 7p21.1 5944 14065 606543 NP_001191073;NP_001191074;NP_001191075;NP_001191076;NP_001191077;NP_055522;NP_478056;NP_848510;NP_848512;XP_006715865;XP_006715866 NM_001204144;NM_001204145;NM_001204146;NM_001204147;NM_001204148;NM_014707;NM_058176;NM_058177;NM_178423;NM_178425;XM_006715802;XM_006715803 ENSP00000080059;ENSP00000408617 Q9UKV0 TRUE can 0 0 0 Last Universal Common Ancestor 0 Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Immune system response,Regulation of intracellular processes and metabolism,Regulation of transcription chr7 18624897 19015577 |HD7|HD7b|HD9|HDAC|HDAC7B|HDAC9B|HDAC9FL|HDRP|MITR| NP_848512 0 FALSE 1 63 8686 0.0960 1
9743 ARHGAP32 Rho GTPase activating protein 32 11q24.3 12257 17399 608541 NP_001136157;NP_055530;XP_005271793;XP_006719010 NM_001142685;NM_014715;XM_005271736;XM_006718947 ENSP00000310561 A7KAX9 TRUE can 0 0 0 Eukaryotes 1 Signal transduction chr11 128838805 129062093 |GC-GAP|GRIT|PX-RICS|RICS|p200RhoGAP|p250GAP| NP_001136157 0 FALSE 1 41 14695 0.1480
9745 ZNF536 zinc finger protein 536 19q12 15825 29025 - NP_055532;XP_005259502;XP_006723575 NM_014717;XM_005259445;XM_006723512 ENSP00000347730 O15090 TRUE can 0 0 0 Eukaryotes 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr19 30934470 31040426 |NA| XP_005259502 0 FALSE 1 3 21 0.6670
9757 KMT2B lysine (K)-specific methyltransferase 2B 19q13.1 6017 15840 606834 NP_055542;XP_006723576;XP_006723577;XP_006723578 NM_014727;XM_006723513;XM_006723514;XM_006723515 ENSP00000222270 Q9UMN6 TRUE can 0 0 0 Last Universal Common Ancestor 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr19 36208921 36229455 |HRX2|MLL1B|WBP-7|WBP7| NP_055542 0 FALSE 1 45 8611 0.0820 2
9758 FRMPD4 FERM and PDZ domain containing 4 Xp22.2 10011 29007 300838 NP_055543;XP_005274689;XP_006724587 NM_014728;XM_005274632;XM_006724524 ENSP00000370057 Q14CM0 TRUE can 0 0 0 Metazoans 0 -1 chrX 12516800 12739974 |PDZD10|PDZK10| XP_005274689 0 FALSE 1 2 64 0.0000
9771 RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5 7p15.3 15208 16862 609527 NP_036426;XP_005249971;XP_005249972;XP_005249973;XP_005249974;XP_006715867 NM_012294;XM_005249914;XM_005249915;XM_005249916;XM_005249917;XM_006715804 ENSP00000343656 Q92565 TRUE can 0 0 0 Eukaryotes 0 Development,Signal transduction chr7 22162027 22396679 |GFR|MR-GEF|REPAC| XP_005249971 0 FALSE 1 8 731 0.0000
9774 BCLAF1 BCL2-associated transcription factor 1 6q23.3 16544 16863 612588 NP_001070908;NP_001070909;NP_055554;XP_005267293;XP_005267294;XP_005267295;XP_005267296 NM_001077440;NM_001077441;NM_014739;XM_005267236;XM_005267237;XM_005267238;XM_005267239;XR_245558;XR_245559 ENSP00000435210 Q9NYF8 TRUE can 0 0 1 Vertebrates 1 Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription chr6 136582403 136601004 |BTF|bK211L9.1| NP_055554 1 FALSE 1 42 8891 0.1600 1
9776 ATG13 autophagy related 13 11p11.2 13809 29091 615088 NP_001136145;NP_001192048;NP_001192049;NP_001192050;NP_001192051;NP_055556;XP_005253319;XP_005253320;XP_005253322;XP_005253323;XP_005253325;XP_006718457;XP_006718458;XP_006718459 NM_001142673;NM_001205119;NM_001205120;NM_001205121;NM_001205122;NM_014741;XM_005253262;XM_005253263;XM_005253265;XM_005253266;XM_005253268;XM_006718394;XM_006718395;XM_006718396 ENSP00000432412 O75143 TRUE can 0 0 0 Metazoans 0 -1 chr11 46665842 46693879 |KIAA0652|PARATARG8| NP_001192048 0 FALSE 1 16 1996 0.4170 8
9794 MAML1 mastermind-like 1 (Drosophila) 5q35 5665 13632 605424 NP_055572 NM_014757 ENSP00000292599 Q92585 TRUE can 0 0 0 Vertebrates 3 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction chr5 179160114 179201875 |Mam-1|Mam1| NP_055572 0 FALSE 1 15 540 0.2760 9
9811 CTIF CBP80/20-dependent translation initiation factor 18q21.1 11083 23925 613178 NP_001135869;NP_055587;XP_005258449;XP_006722646;XP_006722647;XP_006722648;XP_006722649;XP_006722650;XP_006722651;XP_006722652 NM_001142397;NM_014772;XM_005258392;XM_006722583;XM_006722584;XM_006722585;XM_006722586;XM_006722587;XM_006722588;XM_006722589 ENSP00000372459 O43310 TRUE can 0 0 0 Metazoans 0 DNA/RNA metabolism and transcription chr18 46145937 46385927 |Gm672|KIAA0427| XP_005258449 0 FALSE 1 1 0 0.0000
9816 URB2 URB2 ribosome biogenesis 2 homolog (S. cerevisiae) 1q42.13 17178 28967 - NP_055592;XP_005273417 NM_014777;XM_005273360 ENSP00000258243 Q14146 TRUE can 0 0 0 Metazoans 2 -1 chr1 229763381 229795041 |KIAA0133|NET10|NPA2| NP_055592 0 FALSE 1 5 101 0.4000
9817 KEAP1 kelch-like ECH-associated protein 1 19p13.2 12079 23177 606016 NP_036421;NP_987096;XP_005260230;XP_005260231 NM_012289;NM_203500;XM_005260173;XM_005260174 ENSP00000171111 Q14145 TRUE can 0 0 0 Last Universal Common Ancestor 4 Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription chr19 10597331 10610709 |INrf2|KLHL19| NP_036421 0 FALSE 2 87 73041 0.0410 1
9820 CUL7 cullin 7 6p21.1 9901 21024 609577 NP_001161842;NP_055595;XP_005249560;XP_006715348 NM_001168370;NM_014780;XM_005249503;XM_006715285 ENSP00000438788 Q14999 TRUE can 0 0 0 Metazoans 1 Cellular metabolism,Development chr6 43005429 43021596 |3M1|KIAA0076|dJ20C7.5| NP_001161842 0 FALSE 1 611 526710 0.0380 2
9832 JAKMIP2 janus kinase and microtubule interacting protein 2 5q32 - 29067 611197 NP_001257863;NP_001257870;NP_001269211;NP_055605 NM_001270934;NM_001270941;NM_001282282;NM_014790 ENSP00000265272 Q96AA8 TRUE can 0 0 0 Metazoans 3 -1 chr5 146991869 147051369 |JAMIP2| NP_001257870 0 FALSE 1 12 465 0.0300
9844 ELMO1 engulfment and cell motility 1 7p14.1 12102 16286 606420 NP_001034548;NP_001193409;NP_001193411;NP_055615;NP_569709;XP_005249976;XP_005249977;XP_006715868 NM_001039459;NM_001206480;NM_001206482;NM_014800;NM_130442;NR_038120;XM_005249919;XM_005249920;XM_006715805 ENSP00000312185 Q92556 TRUE can 0 0 0 Opisthokonts 0 Cell cycle,Cellular processes,Signal transduction chr7 36895159 37382294 |ELMO-1| NP_001193409 0 FALSE 2 11 1231 0.0550 8
9859 CEP170 centrosomal protein 170kDa 1q44 17172 28920 613023 NP_001035863;NP_001035864;NP_055627;XP_005273418;XP_006711906;XP_006711907;XP_006711908;XP_006711909;XP_006711910;XP_006711911;XP_006711912;XP_006711913;XP_006711914;XP_006711915;XP_006725037;XP_006725038;XP_006725039;XP_006725040;XP_006725041;XP_006725042;XP_006725043;XP_006725044;XP_006725045;XP_006725046;XP_006725047 NM_001042404;NM_001042405;NM_014812;XM_005273361;XM_006711843;XM_006711844;XM_006711845;XM_006711846;XM_006711847;XM_006711848;XM_006711849;XM_006711850;XM_006711851;XM_006711852;XM_006724974;XM_006724975;XM_006724976;XM_006724977;XM_006724978;XM_006724979;XM_006724980;XM_006724981;XM_006724982;XM_006724983;XM_006724984 ENSP00000355500 Q5SW79 TRUE can 0 0 1 Metazoans 0 -1 chr1 243289754 243388582 |FAM68A|KAB|KIAA0470| XP_005273418 1 FALSE 1 21 2148 0.1240
9891 NUAK1 NUAK family, SNF1-like kinase, 1 12q23.3 12171 14311 608130 NP_055655 NM_014840 ENSP00000261402 O60285 TRUE can 0 0 0 Eukaryotes 4 Cellular metabolism,Cellular processes chr12 106460583 106532431 |ARK5| NP_055655 0 FALSE 1 24 5769 0.1520 2
9901 SRGAP3 SLIT-ROBO Rho GTPase activating protein 3 3p25.3 12108 19744 606525 NP_001028289;NP_055665;XP_005265679;XP_006713496 NM_001033116;NM_001033117;NM_014850;XM_005265622;XM_006713433;XR_427300 ENSP00000295713 O43295 TRUE cgc 1 0 0 Eukaryotes 0 Signal transduction chr3 9027206 9290635 |ARHGAP14|MEGAP|WRP| NP_055665 0 FALSE 1 13 1189 0.1030
9914 ATP2C2 ATPase, Ca++ transporting, type 2C, member 2 16q24.1 13812 29103 613082 NP_001273456;NP_055676;XP_006721418 NM_001286527;NM_014861;XM_006721355 ENSP00000262429 O75185 TRUE can 0 0 0 Last Universal Common Ancestor 0 Cellular processes chr16 84402222 84497335 |SPCA2| NP_001273456 0 FALSE 1 1 0 0.0000
9915 ARNT2 aryl-hydrocarbon receptor nuclear translocator 2 15q24 - 16876 606036 NP_055677 NM_014862 ENSP00000307479 Q9HBZ2 TRUE can 0 0 0 Eukaryotes 1 Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction chr15 80743217 80886036 |WEDAS|bHLHe1| NP_055677 0 FALSE 1 60 42905 0.0690
9920 KBTBD11 kelch repeat and BTB (POZ) domain containing 11 8p23.3 17195 29104 - NP_055682;XP_005266100;XP_005266101;XP_005266102;XP_006725175;XP_006725176;XP_006725177 NM_014867;XM_005266043;XM_005266044;XM_005266045;XM_006725112;XM_006725113;XM_006725114 ENSP00000321544 O94819 TRUE can 0 0 0 Eukaryotes 3 -1 chr8 1949359 1951227 |KLHDC7C| NP_055682 0 FALSE 1
9935 MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B 20q11.2-q13.1 7129 6408 608968 NP_005452 NM_005461 ENSP00000362410 Q9Y5Q3 TRUE cgc 1 0 0 Metazoans 4 Cellular metabolism,DNA/RNA metabolism and transcription,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Regulation of transcription chr20 39316522 39317490 |KRML|MCTO| NP_005452 0 FALSE 1 14 6702 0.1430
9940 DLEC1 deleted in lung and esophageal cancer 1 3p21.3 7234 2899 604050 NP_031361;NP_031363;XP_005265687;XP_005265688;XP_006713500;XP_006713501;XP_006713502;XP_006713503;XP_006713504 NM_007335;NM_007336;NM_007337;NM_007338;XM_005265630;XM_005265631;XM_006713437;XM_006713438;XM_006713439;XM_006713440;XM_006713441;XR_427301;XR_427302 ENSP00000242577;ENSP00000276297;ENSP00000308597 Q9Y238 TRUE can 0 0 0 Eukaryotes 0 Cell cycle,Regulation of intracellular processes and metabolism chr3 38080717 38164093 |CFAP81|F56| NP_031363 0 FALSE 1
9947 MAGEC1 melanoma antigen family C, 1 Xq26 2201 6812 300223 NP_005453;XP_003846820 NM_005462;XM_003846772 ENSP00000285879 O60732 TRUE can 0 0 0 Eukaryotes 0 -1 chrX 140993242 140996616 |CT7|CT7.1| XP_003846820 0 FALSE 2 9 732 0.0000
9950 GOLGA5 golgin A5 14q32.12 6079 4428 606918 NP_005104 NM_005113 ENSP00000267731;ENSP00000352111 Q8TBA6 TRUE cgc 1 0 0 Metazoans 3 Cellular metabolism,Cellular processes chr14 93263783 93305788 |GOLIM5|RFG5|ret-II| NP_005104 0 FALSE 1 5 152 0.1000 1
9965 FGF19 fibroblast growth factor 19 11q13.1 4868 3675 603891 NP_005108 NM_005117 ENSP00000294312 O95750 TRUE can 0 0 0 Vertebrates 0 Cell cycle,Cell motility and interactions,Development chr11 69514033 69518644 |NA| NP_005108 0 FALSE 1 2 3 0.0000 23
9967 THRAP3 thyroid hormone receptor associated protein 3 1p34.3 7543 22964 603809 NP_005110;XP_005271428 NM_005119;XM_005271371;XR_246308 ENSP00000346634 Q9Y2W1 TRUE cgc 1 0 1 Vertebrates 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction chr1 36748165 36769615 |TRAP150| NP_005110 1 FALSE 1 88 26522 0.1680 10
9968 MED12 mediator complex subunit 12 Xq13 2176 11957 300188 NP_005111;XP_005262374;XP_005262376 NM_005120;XM_005262317;XM_005262319 ENSP00000354681;ENSP00000363193 Q93074 TRUE cgc 1 0 0 Eukaryotes 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction chrX 70338605 70362065 |ARC240|CAGH45|FGS1|HOPA|MED12S|OHDOX|OKS|TNRC11|TRAP230| XP_005262374 0 FALSE 5 62 14408 0.3180 26
9990 SLC12A6 solute carrier family 12 (potassium/chloride transporter), member 6 15q13 9220 10914 604878 NP_001035959;NP_001035960;NP_001035961;NP_001035962;NP_005126;NP_598408;XP_006720856 NM_001042494;NM_001042495;NM_001042496;NM_001042497;NM_005135;NM_133647;XM_006720793;XR_429476 ENSP00000452776 Q9UHW9 TRUE can 0 0 1 Last Universal Common Ancestor 0 Cellular processes,Multicellular activities,Regulation of intracellular processes and metabolism chr15 34526085 34628881 |ACCPN|KCC3|KCC3A|KCC3B| NP_598408 1 FALSE 1 3 49 0.0000
10006 ABI1 abl-interactor 1 10p11.2 4336 11320 603050 NP_001012768;NP_001012769;NP_001012770;NP_001171587;NP_001171590;NP_001171591;NP_001171592;NP_001171593;NP_001171594;NP_001171595;NP_001171596;NP_005461;XP_005252389;XP_005252390;XP_006717422;XP_006717423;XP_006717424 NM_001012750;NM_001012751;NM_001012752;NM_001178116;NM_001178119;NM_001178120;NM_001178121;NM_001178122;NM_001178123;NM_001178124;NM_001178125;NM_005470;XM_005252332;XM_005252333;XM_006717359;XM_006717360;XM_006717361 ENSP00000365312 Q8IZP0 TRUE cgc 1 0 0 Eukaryotes 0 Cell cycle,Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism,Signal transduction chr10 27037502 27149792 |ABI-1|ABLBP4|E3B1|NAP1BP|SSH3BP|SSH3BP1| NP_005461 0 FALSE 1 75 18695 0.1120 12
10016 PDCD6 programmed cell death 6 5p15.33 3035 8765 601057 NP_001254485;NP_001254486;NP_001254487;NP_001254488;NP_037364 NM_001267556;NM_001267557;NM_001267558;NM_001267559;NM_013232;NR_073609 ENSP00000264933 O75340 TRUE can 0 0 0 Eukaryotes 0 Cell cycle,Cell response to stimuli,Development,Regulation of intracellular processes and metabolism chr5 271836 314627 |ALG-2|PEF1B| NP_037364 0 FALSE 1 53 27131 0.0940 1
10017 BCL2L10 BCL2-like 10 (apoptosis facilitator) 15q21 6071 993 606910 NP_065129;XP_005254160 NM_020396;XM_005254103 ENSP00000260442 Q9HD36 TRUE can 0 0 0 Mammals 0 Cell cycle,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Signal transduction chr15 52402007 52404923 |BCL-B|Boo|Diva| XP_005254160 0 FALSE 1 9 327 0.4170 1
10019 SH2B3 SH2B adaptor protein 3 12q24 5480 29605 605093 NP_005466;XP_005253875;XP_005253876;XP_006719243 NM_005475;XM_005253818;XM_005253819;XM_006719180 ENSP00000345492 Q9UQQ2 TRUE cgc 0 1 0 Vertebrates 8 Development,Signal transduction chr12 111855950 111886103 |LNK| XP_005253875 0 FALSE 1 13 2275 0.4740 2
10057 ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 3q27 6898 56 605251 NP_001018881;NP_005679;XP_005247115;XP_005247116 NM_001023587;NM_005688;XM_005247058;XM_005247059 ENSP00000333926 O15440 TRUE can 0 0 0 Last Universal Common Ancestor 1 -1 chr3 183639091 183732180 |ABC33|EST277145|MOAT-C|MOATC|MRP5|pABC11| NP_005679 0 FALSE 1 7 1823 0.0000
10060 ABCC9 ATP-binding cassette, sub-family C (CFTR/MRP), member 9 12p12.1 3258 60 601439 NP_005682;NP_064693;XP_005253341;XP_005253343;XP_005253344;XP_005253345;XP_005253346;XP_005253347;XP_005253348;XP_006719088 NM_005691;NM_020297;NM_020298;XM_005253284;XM_005253286;XM_005253287;XM_005253288;XM_005253289;XM_005253290;XM_005253291;XM_006719025 ENSP00000261200 O60706 TRUE can 0 0 0 Last Universal Common Ancestor 1 Cell response to stimuli,Cellular processes chr12 21958111 22089608 |ABC37|ATFB12|CANTU|CMD1O| NP_005682 0 FALSE 3 5 2800 0.2000 1
10082 GPC6 glypican 6 13q32 5099 4454 604404 NP_005699;XP_005254074;XP_006719974 NM_005708;XM_005254017;XM_006719911 ENSP00000366246 Q9Y625 TRUE can 0 0 0 Metazoans 0 -1 chr13 93879710 95055468 |OMIMD1| NP_005699 0 FALSE 1 2
10142 AKAP9 A kinase (PRKA) anchor protein 9 7q21-q22 4921 379 604001 NP_005742;NP_671714;XP_005250159;XP_005250160;XP_006715890 NM_005751;NM_147166;NM_147171;NM_147185;XM_005250102;XM_005250103;XM_006715827 ENSP00000348573 Q99996 TRUE cgc 1 0 0 Vertebrates 2 Multicellular activities,Signal transduction chr7 91570414 91737949 |AKAP-9|AKAP350|AKAP450|CG-NAP|HYPERION|LQT11|MU-RMS-40.16A|PPP1R45|PRKA9|YOTIAO| XP_005250159 0 FALSE 2 58 17469 0.0340 14
10146 G3BP1 GTPase activating protein (SH3 domain) binding protein 1 5q33.1 6569 30292 608431 NP_005745;NP_938405;XP_006714812;XP_006714813 NM_005754;NM_198395;XM_006714749;XM_006714750 ENSP00000348578 Q13283 TRUE can 0 0 1 Eukaryotes 7 Signal transduction chr5 151166182 151183649 |G3BP|HDH-VIII| NP_005745 1 FALSE 1 91 36628 0.1170 1
10186 LHFP lipoma HMGIC fusion partner 13q12 9464 6586 606710 NP_005771;XP_006719813 NM_005780;XM_006719750 ENSP00000368908 Q9Y693 TRUE cgc 1 0 0 Metazoans 2 -1 chr13 39918076 40175353 |NA| NP_005771 0 FALSE 1
10215 OLIG2 oligodendrocyte lineage transcription factor 2 21q22.11 7334 9398 606386 NP_005797;XP_005260965 NM_005806;XM_005260908 ENSP00000331040 Q13516 TRUE cgc 1 0 0 Metazoans 2 Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Regulation of transcription chr21 34399171 34400139 |BHLHB1|OLIGO2|PRKCBP2|RACK17|bHLHe19| NP_005797 0 FALSE 1 6 963 0.0670
10216 PRG4 proteoglycan 4 1q25-q31 5047 9364 604283 NP_001121180;NP_001121181;NP_001121182;NP_005798;XP_005244879;XP_006711171 NM_001127708;NM_001127709;NM_001127710;NM_005807;XM_005244822;XM_006711108 ENSP00000251473;ENSP00000399679 Q92954 TRUE can 0 0 0 Eukaryotes 0 -1 chr1 186266008 186282907 |CACP|HAPO|JCAP|SZP|bG174L6.2| NP_005798 0 FALSE 1 1 0 0.0000
10231 RCAN2 regulator of calcineurin 2 6p12.3 5342 3041 604876 NP_001238902;NP_001238903;NP_005813;XP_006715011 NM_001251973;NM_001251974;NM_005822;XM_006714948 ENSP00000329454 Q14206 TRUE can 0 0 0 Metazoans 0 Development,Signal transduction chr6 46190881 46424713 |CSP2|DSCR1L1|MCIP2|ZAKI-4|ZAKI4| NP_001238902 0 FALSE 1 2 9 0.0000
10240 MRPS31 mitochondrial ribosomal protein S31 13q14.11 10098 16632 611992 NP_005821 NM_005830 ENSP00000315397 Q92665 TRUE can 0 0 0 Metazoans 2 -1 chr13 41303511 41345272 |IMOGN38|MRP-S31|S31mt| NP_005821 0 FALSE 1 17 1091 0.0810 6
10243 GPHN gephyrin 14q23.3 4893 15465 603930 NP_001019389;NP_065857;XP_005267307;XP_005267310;XP_005267311;XP_006720066 NM_001024218;NM_020806;XM_005267250;XM_005267253;XM_005267254;XM_006720003 ENSP00000417901 Q9NQX3 TRUE cgc 1 0 0 Last Universal Common Ancestor 0 Cellular metabolism chr14 66975246 67647651 |GEPH|GPH|GPHRYN|MOCODC| XP_005267307 0 FALSE 1 22 18075 0.0350
10251 SPRY3 sprouty homolog 3 (Drosophila) Xq28 and Yq12 3917 11271 300531 NP_005831;XP_005274699;XP_005274700;XP_005274857 NM_005840;XM_005274642;XM_005274643;XM_005274800 ENSP00000302978 O43610 TRUE can 0 0 1 Metazoans 0 Signal transduction chrX 155003534 155004397 |HSPRY3|spry-3| NP_005831 1 FALSE 1 1 0 0.0000
10270 AKAP8 A kinase (PRKA) anchor protein 8 19p13.1 5258 378 604692 NP_005849;XP_005259763 NM_005858;XM_005259706;XR_244062 ENSP00000269701 O43823 TRUE can 0 0 0 Vertebrates 4 Cell cycle,DNA/RNA metabolism and transcription,Signal transduction chr19 15465729 15487826 |AKAP 95|AKAP-8|AKAP-95|AKAP95| NP_005849 0 FALSE 1 32 3946 0.1940
10272 FSTL3 follistatin-like 3 (secreted glycoprotein) 19p13 5632 3973 605343 NP_005851 NM_005860 ENSP00000166139 O95633 TRUE cgc 1 0 0 Eukaryotes 8 Regulation of intracellular processes and metabolism,Signal transduction chr19 676424 681705 |FLRG|FSRP| NP_005851 0 FALSE 1 6 6658 0.0670 1
10301 DLEU1 deleted in lymphocytic leukemia 1 (non-protein coding) 13q14.3 16150 13747 605765 - NM_005887;NR_002605;NR_109973;NR_109974 ENSP00000367422 NA TRUE can 0 0 -1 Mammals 0 -1 - 0 0 |BCMS|BCMS1|DLB1|LINC00021|NCRNA00021|XTP6| - -1 FALSE 1
10320 IKZF1 IKAROS family zinc finger 1 (Ikaros) 7p12.2 4318 13176 603023 NP_001207694;NP_001207695;NP_001207696;NP_001207697;NP_001207698;NP_001207699;NP_001207700;NP_001207701;NP_001207702;NP_001207703;NP_001207704;NP_001207705;NP_006051 NM_001220765;NM_001220766;NM_001220767;NM_001220768;NM_001220769;NM_001220770;NM_001220771;NM_001220772;NM_001220773;NM_001220774;NM_001220775;NM_001220776;NM_006060 ENSP00000331614 Q13422 TRUE cgc 1 1 0 Eukaryotes 1 Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription chr7 50358658 50468322 |Hs.54452|IKAROS|LYF1|LyF-1|PPP1R92|PRO0758|ZNFN1A1| NP_006051 0 FALSE 1 86 27617 0.0510 2
10326 SIRPB1 signal-regulatory protein beta 1 20p13 4866 15928 603889 NP_001077379;NP_001129316;NP_006056;XP_005260698;XP_005260700;XP_005260701;XP_006710313;XP_006723598 NM_001083910;NM_001135844;NM_006065;XM_005260641;XM_005260643;XM_005260644;XM_006710250;XM_006723535 ENSP00000279477;ENSP00000454437 O00241 TRUE can 0 0 4 Vertebrates 0 Signal transduction chr20 1579473 1600590 |CD172b|SIRP-BETA-1| NP_001129316 4 FALSE 1 5 2960 0.1000 1
10335 MRVI1 murine retrovirus integration site 1 homolog 11p15 5242 7237 604673 NP_001092049;NP_001093633;NP_001093637;NP_001193809;NP_001193810;NP_569056 NM_001098579;NM_001100163;NM_001100167;NM_001206880;NM_001206881;NM_130385 ENSP00000412130 Q9Y6F6 TRUE can 0 0 0 Metazoans 0 -1 chr11 10597882 10715149 |IRAG|JAW1L| NP_569056 0 FALSE 1 3 41 0.3330 2
10342 TFG TRK-fused gene 3q12.2 3932 11758 602498 NP_001007566;NP_001182407;NP_001182408;NP_006061;XP_005247123;XP_006713535;XP_006713536 NM_001007565;NM_001195478;NM_001195479;NM_006070;XM_005247066;XM_006713472;XM_006713473 ENSP00000240851 Q92734 TRUE cgc 1 0 1 Metazoans 1 Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism,Signal transduction chr3 100432530 100467372 |SPG57|TF6|TRKT3| NP_001007566 1 FALSE 1 55 40706 0.0880
10347 ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7 19p13.3 9255 37 605414 NP_061985;XP_006722679;XP_006722680;XP_006722681 NM_019112;NM_033308;XM_006722616;XM_006722617;XM_006722618;XR_430126 ENSP00000263094 Q8IZY2 TRUE can 0 0 0 Last Universal Common Ancestor 1 Cellular processes chr19 1041361 1065421 |ABCA-SSN|ABCX| NP_061985 0 FALSE 1
10349 ABCA10 ATP-binding cassette, sub-family A (ABC1), member 10 17q24 12400 30 612508 NP_525021 NM_080282 ENSP00000269081 Q8WWZ4 TRUE can 0 0 0 Last Universal Common Ancestor 0 -1 chr17 67144971 67218851 |EST698739| NP_525021 0 FALSE 1 2 0 1.0000
10365 KLF2 Kruppel-like factor 2 19p13.11 3602 6347 602016 NP_057354 NM_016270 ENSP00000248071 Q9Y5W3 TRUE can 0 0 0 Eukaryotes 3 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr19 16435735 16437839 |LKLF| NP_057354 0 FALSE 1 10 1929 0.1780
10395 DLC1 DLC1 Rho GTPase activating protein 8p22 5035 2897 604258 NP_001157743;NP_006085;NP_079043;NP_872584;XP_005273431;XP_005273432 NM_001164271;NM_006094;NM_024767;NM_182643;XM_005273374;XM_005273375 ENSP00000242577;ENSP00000276297;ENSP00000308597 Q96QB1 TRUE can 0 0 0 Eukaryotes 5 Cell cycle,Cell motility and interactions,Cellular metabolism,Cellular processes,Development,Regulation of intracellular processes and metabolism,Signal transduction chr8 12943323 13357580 |ARHGAP7|STARD12|p122-RhoGAP| NP_872584 0 FALSE 1 41 18967 0.0240
10397 NDRG1 N-myc downstream regulated 1 8q24.3 5586 7679 605262 NP_001128714;NP_001245361;NP_001245362;NP_006087 NM_001135242;NM_001258432;NM_001258433;NM_006096 ENSP00000319977 Q92597 TRUE cgc 1 0 0 Eukaryotes 2 Cell response to stimuli chr8 134251124 134296554 |CAP43|CMT4D|GC4|HMSNL|NMSL|PROXY1|RIT42|RTP|TDD5| NP_001128714 0 FALSE 1 89 38446 0.0760
10403 NDC80 NDC80 kinetochore complex component 18p11.32 6277 16909 607272 NP_006092 NM_006101 ENSP00000261597 O14777 TRUE can 0 0 0 Eukaryotes 1 Cell cycle,Cellular processes,DNA/RNA metabolism and transcription,Signal transduction chr18 2572985 2616570 |HEC|HEC1|HsHec1|KNTC2|TID3|hsNDC80| NP_006092 0 FALSE 1 53 16910 0.0830 11
10404 CPQ carboxypeptidase Q 8q22.2 7140 16910 - NP_057218;XP_005250812;XP_006716561 NM_016134;XM_005250755;XM_006716498;XR_428374 ENSP00000220763 Q9Y646 TRUE can 0 0 0 Last Universal Common Ancestor 0 Cellular metabolism chr8 97797126 98155408 |LDP|PGCP| NP_057218 0 FALSE 1
10430 TMEM147 transmembrane protein 147 19q13.1 17633 30414 613585 NP_001229526;NP_001229527;NP_116024 NM_001242597;NM_001242598;NM_032635 ENSP00000222284 Q9BVK8 TRUE can 0 0 0 Eukaryotes 1 -1 chr19 36036642 36038346 |NIFIE14| NP_116024 0 FALSE 1 9 1955 0.0000
10436 EMG1 EMG1 N1-specific pseudouridine methyltransferase 12p13.3 - 16912 611531 NP_006322 NM_006331 ENSP00000470560 Q92979 TRUE can 0 0 0 Last Universal Common Ancestor 0 DNA/RNA metabolism and transcription,Regulation of transcription chr12 7080087 7084968 |C2F|Grcc2f|NEP1| NP_006322 0 FALSE 1 18 13934 0.0980
10482 NXF1 nuclear RNA export factor 1 11q12-q13 4035 8071 602647 NP_001074960;NP_006353;XP_006718481;XP_006718482;XP_006718483 NM_001081491;NM_006362;XM_006718418;XM_006718419;XM_006718420 ENSP00000294172 Q9UBU9 TRUE can 0 0 0 Eukaryotes 0 Cellular processes,DNA/RNA metabolism and transcription chr11 62560113 62571451 |MEX67| NP_006353 0 FALSE 1 1071 3261825 0.0080 4
10499 NCOA2 nuclear receptor coactivator 2 8q13.3 9066 7669 601993 NP_006531;XP_005251185;XP_005251186;XP_005251187;XP_005251188;XP_005251189;XP_005251190 NM_006540;XM_005251128;XM_005251129;XM_005251130;XM_005251131;XM_005251132;XM_005251133 ENSP00000399968 Q15596 TRUE cgc 1 0 0 Eukaryotes 1 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction chr8 71033537 71128980 |KAT13C|NCoA-2|TIF2|bHLHe75| NP_006531 0 FALSE 1 77 24799 0.1100 10
10512 SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C 7q21-q31 4034 10725 602645 NP_006370;XP_005250170 NM_006379;XM_005250113 ENSP00000265361 Q99985 TRUE can 0 0 0 Vertebrates 3 Signal transduction chr7 80374213 80546097 |SEMAE|SemE| NP_006370 0 FALSE 1 2 0 1.0000
10533 ATG7 autophagy related 7 3p25.3 12293 16935 608760 NP_001129503;NP_001138384;NP_006386;XP_005264860;XP_006712994;XP_006712995;XP_006712996;XP_006712997;XP_006712998;XP_006712999 NM_001136031;NM_001144912;NM_006395;XM_005264803;XM_006712931;XM_006712932;XM_006712933;XM_006712934;XM_006712935;XM_006712936 ENSP00000346437 O95352 TRUE can 0 0 0 Last Universal Common Ancestor 1 Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism chr3 11340170 11468400 |APG7-LIKE|APG7L|GSA7| NP_006386 0 FALSE 1 41 11728 0.1520 4
10568 SLC34A2 solute carrier family 34 (type II sodium/phosphate contransporter), member 2 4p15.2 7251 11020 604217 NP_001171469;NP_001171470;NP_006415 NM_001177998;NM_001177999;NM_006424 ENSP00000371483 O95436 TRUE cgc 1 0 0 Last Universal Common Ancestor 2 Cellular metabolism,Cellular processes chr4 25664123 25678368 |NAPI-3B|NAPI-IIb|NPTIIb| NP_006415 0 FALSE 1 1 0 0.0000
10599 SLCO1B1 solute carrier organic anion transporter family, member 1B1 12p 9214 10959 604843 NP_006437 NM_006446 ENSP00000256958 Q9Y6L6 TRUE can 0 0 2 Metazoans 2 Cellular processes chr12 21294509 21392120 |OATP-C|OATP1B1|OATP2|OATPC|SLC21A6| NP_006437 2 FALSE 2
10600 USP16 ubiquitin specific peptidase 16 21q22.11 6881 12614 604735 NP_001001992;NP_001027582;NP_006438 NM_001001992;NM_001032410;NM_006447 ENSP00000289865;ENSP00000334808 Q9Y5T5 TRUE can 0 0 0 Eukaryotes 0 Cellular metabolism chr21 30400235 30426505 |UBP-M|UBPM| NP_001027582 0 FALSE 1 18 712 0.0780
10605 PAIP1 poly(A) binding protein interacting protein 1 5p12 5539 16945 605184 NP_006442;NP_877590;NP_899152;XP_005248287 NM_006451;NM_182789;NM_183323;XM_005248230 ENSP00000302768 Q9H074 TRUE can 0 0 1 Eukaryotes 1 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr5 43527481 43556948 |NA| NP_006442 1 FALSE 1 15 486 0.2100 3
10620 ARID3B AT rich interactive domain 3B (BRIGHT-like) 15q24 9806 14350 612457 NP_006456;XP_005254186 NM_006465;XM_005254129 ENSP00000343126 Q8IVW6 TRUE can 0 0 1 Eukaryotes 3 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr15 74836278 74888112 |DRIL2| XP_005254186 1 FALSE 1 8 1553 0.1430
10628 TXNIP thioredoxin interacting protein 1q21.1 5964 16952 606599 NP_006463 NM_006472 ENSP00000358323;ENSP00000462521 Q9H3M7 TRUE can 0 0 0 Eukaryotes 6 Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription chr1 145438803 145441056 |EST01027|HHCPA78|THIF|VDUP1| NP_006463 0 FALSE 2 22 3620 0.1210 1
10664 CTCF CCCTC-binding factor (zinc finger protein) 16q21-q22.3 5005 13723 604167 NP_001177951;NP_006556;XP_005255832 NM_001191022;NM_006565;XM_005255775 ENSP00000264010 P49711 TRUE can 0 0 0 Eukaryotes 4 Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr16 67644736 67671772 |MRD21| NP_006556 0 FALSE 3 44 10375 0.0950 6
10672 GNA13 guanine nucleotide binding protein (G protein), alpha 13 17q24.3 - 4381 604406 NP_001269354;NP_006563 NM_001282425;NM_006572 ENSP00000400717 Q14344 TRUE can 0 0 0 Eukaryotes 6 Cell motility and interactions,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Signal transduction chr17 63010378 63052711 |NA| NP_006563 0 FALSE 1 44 58304 0.0490 10
10693 CCT6B chaperonin containing TCP1, subunit 6B (zeta 2) 17q12 9873 1621 610730 NP_001180458;NP_001180459;NP_006575;XP_006721704;XP_006721705 NM_001193529;NM_001193530;NM_006584;XM_006721641;XM_006721642 ENSP00000327191 Q92526 TRUE can 0 0 2 Eukaryotes 2 Cellular metabolism,Cellular processes,Development,Multicellular activities chr17 33255070 33288412 |CCT-zeta-2|CCTZ-2|Cctz2|TCP-1-zeta-2|TSA303| NP_006575 2 FALSE 1 14 126 0.4400
10718 NRG3 neuregulin 3 10q22-q23 16115 7999 605533 NP_001010848;NP_001159444;NP_001159445;XP_005269501 NM_001010848;NM_001165972;NM_001165973;XM_005269444 ENSP00000361214 P56975 TRUE can 0 0 0 Vertebrates 0 Cell cycle,Development,Regulation of intracellular processes and metabolism,Signal transduction chr10 83635097 84745358 |HRG3|pro-NRG3| XP_005269501 0 FALSE 1 1 0 0.0000
10735 STAG2 stromal antigen 2 Xq25 5077 11355 300826 NP_001036214;NP_001036215;NP_001036216;NP_001269347;NP_006594;XP_005262414;XP_005262415;XP_005262416;XP_005262417;XP_005262418;XP_006724790;XP_006724791 NM_001042749;NM_001042750;NM_001042751;NM_001282418;NM_006603;XM_005262357;XM_005262358;XM_005262359;XM_005262360;XM_005262361;XM_006724727;XM_006724728 ENSP00000218089 Q8N3U4 TRUE cgc 0 1 0 Eukaryotes 3 Cell cycle chrX 123156478 123229302 |SA-2|SA2|SCC3B|bA517O1.1| NP_001036214 0 FALSE 5 24 1837 0.3120 25
10801 SEPT9 septin 9 17q25 10360 7323 604061 NP_001106963;NP_001106964;NP_001106965;NP_001106966;NP_001106967;NP_001106968;NP_006631;XP_005257016;XP_005257017;XP_005257018;XP_005257019;XP_006721706;XP_006721707 NM_001113491;NM_001113492;NM_001113493;NM_001113494;NM_001113495;NM_001113496;NM_006640;XM_005256959;XM_005256960;XM_005256961;XM_005256962;XM_006721643;XM_006721644 ENSP00000391249;ENSP00000461549 Q9UHD8 TRUE cgc 1 0 0 Opisthokonts 3 Cell cycle,Cellular metabolism,Regulation of intracellular processes and metabolism chr17 75303222 75494737 |AF17q25|MSF1|PNUTL4|SINT1|SeptD1| NP_001106963 0 FALSE 2 45 16121 0.0820 3
10841 FTCD formimidoyltransferase cyclodeaminase 21q22.3 8430 3974 606806 NP_006648;NP_996848;XP_006724023;XP_006724024;XP_006724025 NM_006657;NM_206965;XM_006723960;XM_006723961;XM_006723962 ENSP00000291670 O95954 TRUE can 0 0 0 Last Universal Common Ancestor 1 Cellular metabolism chr21 47556904 47575437 |LCHC1| NP_006648 0 FALSE 1 4 177 0.1670
10847 SRCAP Snf2-related CREBBP activator protein 16p11.2 18103 16974 611421 NP_006653 NM_006662 ENSP00000262518 Q6ZRS2 TRUE can 0 0 0 Last Universal Common Ancestor 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr16 30715385 30751051 |DOMO1|FLHS|SWR1| NP_006653 0 FALSE 1 25 1303 0.2200 6
10849 CD3EAP CD3e molecule, epsilon associated protein 19q13.3 125 24219 107325 NP_036231;XP_005258482 NM_012099;XM_005258425 ENSP00000310966 O15446 TRUE can 0 0 0 Vertebrates 1 Cellular metabolism,DNA/RNA metabolism and transcription,Signal transduction chr19 45910351 45912756 |ASE-1|PAF49| XP_005258482 0 FALSE 1 19 570 0.2510 4
10859 LILRB1 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1 19q13.4 7273 6605 604811 NP_001075106;NP_001075107;NP_001075108;NP_001265327;NP_001265328;NP_006660;XP_005277104;XP_006726309;XP_006726310;XP_006726311;XP_006726312;XP_006726313;XP_006726314;XP_006726315;XP_006726344;XP_006726345;XP_006726346;XP_006726347;XP_006726348;XP_006726349;XP_006726350 NM_001081637;NM_001081638;NM_001081639;NM_001278398;NM_001278399;NM_006669;NR_103518;XM_005277047;XM_006726246;XM_006726247;XM_006726248;XM_006726249;XM_006726250;XM_006726251;XM_006726252;XM_006726281;XM_006726282;XM_006726283;XM_006726284;XM_006726285;XM_006726286;XM_006726287;XR_254255;XR_431086;XR_431087;XR_431094;XR_431095;XR_431096 ENSP00000315997;ENSP00000459143;ENSP00000461579 Q8NHL6 TRUE can 0 0 3 Vertebrates 0 Cell response to stimuli chr19 55085542 55148326 |CD85J|ILT-2|ILT2|LIR-1|LIR1|MIR-7|MIR7| NP_001075106 3 FALSE 1 8 854 0.1790 1
10880 ACTL7B actin-like 7B 9q31 - 162 604304 NP_006677 NM_006686 ENSP00000363799 Q9Y614 TRUE can 0 0 0 Last Universal Common Ancestor 0 -1 chr9 111616966 111618210 |Tact1| NP_006677 0 FALSE 1 1 0 0.0000
10892 MALT1 mucosa associated lymphoid tissue lymphoma translocation gene 1 18q21 6892 6819 604860 NP_006776;NP_776216;XP_005266701 NM_006785;NM_173844;XM_005266644 ENSP00000319279 Q9UDY8 TRUE cgc 1 0 0 Last Universal Common Ancestor 1 Cell cycle,Cell response to stimuli,Cellular metabolism,Cellular processes,Development,Immune system response,Regulation of intracellular processes and metabolism,Signal transduction chr18 56338876 56415071 |IMD12|MLT1| NP_006776 0 FALSE 1 33 3310 0.2010 18
10902 BRD8 bromodomain containing 8 5q31 4166 19874 602848 NP_001157798;NP_006687;NP_631938;XP_005271912;XP_005271913;XP_005271914;XP_005271916;XP_005271917;XP_005271918;XP_005271921;XP_005271922;XP_006714587;XP_006714588 NM_001164326;NM_006696;NM_139199;NM_183359;XM_005271855;XM_005271856;XM_005271857;XM_005271859;XM_005271860;XM_005271861;XM_005271864;XM_005271865;XM_006714524;XM_006714525;XR_427701 ENSP00000254900 Q9H0E9 TRUE can 0 0 0 Eukaryotes 3 Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction chr5 137475766 137513354 |NA| XP_005271912 0 FALSE 1 22 2130 0.2600 12
10915 TCERG1 transcription elongation regulator 1 5q31 10393 15630 605409 NP_001035095;NP_006697;XP_005268422;XP_005268423;XP_005268424;XP_006714817 NM_001040006;NM_006706;XM_005268365;XM_005268366;XM_005268367;XM_006714754;XR_245850 ENSP00000296702 O14776 TRUE can 0 0 0 Eukaryotes 1 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr5 145826913 145890202 |CA150|TAF2S|Urn1| XP_005268422 0 FALSE 1 72 10806 0.1560 4
10917 BTNL3 butyrophilin-like 3 5q35.3 8393 1143 606192 NP_932079;XP_005265858 NM_006707;NM_197975;XM_005265801 ENSP00000341787 Q6UXE8 TRUE can 0 0 0 Vertebrates 1 -1 chr5 180416029 180432869 |BTN9.1|BTNLR| NP_932079 0 FALSE 1
10930 APOBEC2 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2 6p21 - 605 604797 NP_006780 NM_006789 ENSP00000244669 Q9Y235 TRUE can 0 0 0 Vertebrates 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of transcription chr6 41021087 41029607 |ARCD1| NP_006780 0 FALSE 1 1 0 0.0000
10957 PNRC1 proline-rich nuclear receptor coactivator 1 6q15 8412 17278 606714 NP_006804 NM_006813 ENSP00000336931 Q12796 TRUE can 0 0 0 Vertebrates 2 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr6 89790614 89793912 |B4-2|PNAS-145|PROL2| NP_006804 0 FALSE 1 18 3095 0.0460
10962 MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 1q21 - 16997 604684 NP_006809 NM_006818 ENSP00000357917 Q13015 TRUE cgc 1 0 0 Vertebrates 4 -1 chr1 151039701 151039970 |AF1Q| NP_006809 0 FALSE 1 3 37 0.3330
10978 CLP1 cleavage and polyadenylation factor I subunit 1 11q12 16382 16999 608757 NP_001136069;NP_006822;XP_006718488 NM_001142597;NM_006831;XM_006718425 ENSP00000328773 Q92989 TRUE cgc 1 0 0 Eukaryotes 1 DNA/RNA metabolism and transcription,Regulation of transcription chr11 57426949 57428905 |HEAB|hClp1| NP_006822 0 FALSE 1 12 6682 0.1670 7
10991 SLC38A3 solute carrier family 38, member 3 3p21.3 11980 18044 604437 NP_006832;XP_006713017 NM_006841;XM_006712954 - Q99624 TRUE can 0 0 0 - 0 Cellular processes chr3 50251633 50257606 |SN1| NP_006832 0 FALSE 1 4 145 0.0000
11059 WWP1 WW domain containing E3 ubiquitin protein ligase 1 8q21 3811 17004 602307 NP_008944;XP_005250817;XP_005250818 NM_007013;XM_005250760;XM_005250761 ENSP00000265428 Q9H0M0 TRUE can 0 0 1 Eukaryotes 0 Cell motility and interactions,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Other,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction chr8 87386280 87479119 |AIP5|Tiul1|hSDRP1| NP_008944 1 FALSE 1 69 40237 0.0430 2
11064 CNTRL centriolin 9q33.2 5691 1858 605496 NP_008949;XP_005251736;XP_006717003;XP_006717004;XP_006717005;XP_006717006;XP_006717007 NM_007018;XM_005251679;XM_006716940;XM_006716941;XM_006716942;XM_006716943;XM_006716944 ENSP00000238341 Q7Z7A1 TRUE cgc 1 0 0 Eukaryotes 2 -1 chr9 123850605 123937502 |CEP110|bA165P4.1| NP_008949 0 FALSE 1 4 43 0.1670 15
11086 ADAM29 ADAM metallopeptidase domain 29 4q34 5306 207 604778 NP_001124175;NP_001124176;NP_001124177;NP_001265054;NP_001265055;NP_001265056;NP_055084;XP_005262761;XP_005262762 NM_001130703;NM_001130704;NM_001130705;NM_001278125;NM_001278126;NM_001278127;NM_014269;XM_005262704;XM_005262705 ENSP00000352177 Q9UKF5 TRUE can 0 0 0 Eukaryotes 1 Cellular metabolism,Development,Multicellular activities chr4 175896677 175899136 |CT73|svph1| NP_001124175 0 FALSE 1
11116 FGFR1OP FGFR1 oncogene partner 6q27 - 17012 605392 NP_001265619;NP_008976;NP_919410 NM_001278690;NM_007045;NM_194429 ENSP00000355812 O95684 TRUE cgc 1 0 0 Metazoans 1 Cell cycle,Regulation of intracellular processes and metabolism chr6 167412901 167453463 |NA| NP_008976 0 FALSE 1 13 697 0.1670 15
11122 PTPRT protein tyrosine phosphatase, receptor type, T 20q12-q13 6690 9682 608712 NP_008981;NP_573400;XP_006723748;XP_006723749;XP_006723750;XP_006723751;XP_006723752 NM_007050;NM_133170;XM_006723685;XM_006723686;XM_006723687;XM_006723688;XM_006723689 ENSP00000362283 O14522 TRUE can 0 0 0 Last Universal Common Ancestor 1 Cellular metabolism,Cellular processes,Signal transduction chr20 40709522 41818373 |RPTPrho| NP_573400 0 FALSE 2 5 594 0.2000
11168 PSIP1 PC4 and SFRS1 interacting protein 1 9p22.3 4688 9527 603620 NP_001121689;NP_066967;NP_150091;XP_005251412;XP_005251413;XP_005251414;XP_005251415 NM_001128217;NM_021144;NM_033222;XM_005251355;XM_005251356;XM_005251357;XM_005251358 ENSP00000370109 O75475 TRUE cgc 1 0 0 Eukaryotes 5 Cellular metabolism,DNA/RNA metabolism and transcription,Multicellular activities,Other,Regulation of intracellular processes and metabolism,Regulation of transcription chr9 15465521 15510186 |DFS70|LEDGF|PAIP|PSIP2| NP_001121689 0 FALSE 1 43 2518 0.1280 8
11197 WIF1 WNT inhibitory factor 1 12q14.3 5541 18081 605186 NP_009122 NM_007191 ENSP00000286574 Q9Y5W5 TRUE cgc 1 0 0 Eukaryotes 1 Signal transduction chr12 65445132 65514971 |WIF-1| NP_009122 0 FALSE 1 9 31257 0.0000 1
11200 CHEK2 checkpoint kinase 2 22q12.1 5084 16627 604373 NP_001005735;NP_001244316;NP_009125;NP_665861;XP_006724177;XP_006724178;XP_006724179 NM_001005735;NM_001257387;NM_007194;NM_145862;XM_006724114;XM_006724115;XM_006724116;XR_244350 ENSP00000295887;ENSP00000372023 O96017 TRUE cgc 0 1 0 Last Universal Common Ancestor 0 Cell cycle,Cellular metabolism,Cellular processes,Development,Regulation of intracellular processes and metabolism,Signal transduction chr22 29083888 29130709 |CHK2|HuCds1|LFS2|PP1425|RAD53|hCds1| NP_001005735 0 FALSE 5 88 71051 0.0630 2
11214 AKAP13 A kinase (PRKA) anchor protein 13 15q24-q25 5253 371 604686 NP_001257475;NP_006729;NP_009131;XP_005254896;XP_005254897;XP_005254898;XP_005254899;XP_005254900;XP_005254901;XP_005254902;XP_005254903;XP_005254904;XP_005254905;XP_005254906;XP_005254907;XP_005254908;XP_005254909;XP_005254910;XP_005254911;XP_005254912;XP_005254913;XP_006720439;XP_006720440;XP_006720441 NM_001270546;NM_006738;NM_007200;NM_144767;XM_005254839;XM_005254840;XM_005254841;XM_005254842;XM_005254843;XM_005254844;XM_005254845;XM_005254846;XM_005254847;XM_005254848;XM_005254849;XM_005254850;XM_005254851;XM_005254852;XM_005254853;XM_005254854;XM_005254855;XM_005254856;XM_006720376;XM_006720377;XM_006720378 ENSP00000354718 Q12802 TRUE can 0 0 0 Eukaryotes 1 Signal transduction chr15 86064659 86287905 |AKAP-13|AKAP-Lbc|ARHGEF13|HA-3|Ht31|LBC|PRKA13|PROTO-LB|PROTO-LBC|c-lbc| XP_005254896 0 FALSE 2 21 3556 0.1000
11215 AKAP11 A kinase (PRKA) anchor protein 11 13q14.11 5261 369 604696 NP_057332;XP_005266304;XP_005266305;XP_005266306;XP_005266307 NM_016248;NM_144490;XM_005266247;XM_005266248;XM_005266249;XM_005266250 ENSP00000025301 Q9UKA4 TRUE can 0 0 0 Vertebrates 13 Signal transduction chr13 42860485 42893361 |AKAP-11|AKAP220|PPP1R44|PRKA11| NP_057332 0 FALSE 1 15 1119 0.2670
11228 RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 12p12.3 7084 13232 608231 NP_001158218;NP_001158219;NP_001158220;NP_009142;XP_006719090;XP_006719091 NM_001164746;NM_001164747;NM_001164748;NM_007211;XM_006719027;XM_006719028 ENSP00000282884 Q8NHQ8 TRUE can 0 0 0 Metazoans 8 Signal transduction chr12 26208277 26221748 |HOJ1| NP_001158218 0 FALSE 1 13 2374 0.2560
11280 SCN11A sodium channel, voltage-gated, type XI, alpha subunit 3p22.2 5090 10583 604385 NP_001274152;NP_054858 NM_001287223;NM_014139 ENSP00000307599 Q9UI33 TRUE can 0 0 0 Eukaryotes 0 Cellular processes chr3 38888188 38991853 |FEPS3|HSAN7|NAV1.9|NaN|PN5|SCN12A|SNS-2| NP_001274152 0 FALSE 1
11338 U2AF2 U2 small nuclear RNA auxiliary factor 2 19q13.42 1872 23156 191318 NP_001012496;NP_009210;XP_006723057 NM_001012478;NM_007279;XM_006722994 ENSP00000307863 P26368 TRUE can 0 0 0 Eukaryotes 0 DNA/RNA metabolism and transcription,Regulation of transcription chr19 56166471 56185431 |U2AF65| NP_009210 0 FALSE 1 141 46824 0.1550 16
22806 IKZF3 IKAROS family zinc finger 3 (Aiolos) 17q21 - 13178 606221 NP_001244337;NP_001244338;NP_001244339;NP_001244340;NP_001244341;NP_001244342;NP_001244343;NP_001271443;NP_001271444;NP_001271445;NP_036613;NP_899051;NP_899052;NP_899053;NP_899054;NP_899055 NM_001257408;NM_001257409;NM_001257410;NM_001257411;NM_001257412;NM_001257413;NM_001257414;NM_001284514;NM_001284515;NM_001284516;NM_012481;NM_183228;NM_183229;NM_183230;NM_183231;NM_183232 ENSP00000344544 Q9UKT9 TRUE can 0 0 0 Eukaryotes 0 Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription chr17 37922046 37988405 |AIO|AIOLOS|ZNFN1A3| NP_036613 0 FALSE 1 85 37179 0.0400 2
22807 IKZF2 IKAROS family zinc finger 2 (Helios) 2q34 - 13177 606234 NP_001072994;NP_057344;XP_005246440;XP_005246441;XP_005246442;XP_005246443;XP_006712429;XP_006712430;XP_006712431 NM_001079526;NM_016260;XM_005246383;XM_005246384;XM_005246385;XM_005246386;XM_006712366;XM_006712367;XM_006712368 ENSP00000410447 Q9UKS7 TRUE can 0 0 0 Eukaryotes 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr2 213872087 214013368 |ANF1A2|HELIOS|ZNF1A2|ZNFN1A2| XP_005246440 0 FALSE 1 17 893 0.3820
22852 ANKRD26 ankyrin repeat domain 26 10p12.1 16491 29186 610855 NP_001242982;NP_055730;XP_006717486;XP_006717487;XP_006717488;XP_006717489;XP_006717490;XP_006717491;XP_006717492;XP_006717493;XP_006717494;XP_006717495 NM_001256053;NM_014915;XM_006717423;XM_006717424;XM_006717425;XM_006717426;XM_006717427;XM_006717428;XM_006717429;XM_006717430;XM_006717431;XM_006717432 ENSP00000365255 Q9UPS8 TRUE can 0 0 0 Last Universal Common Ancestor 0 -1 chr10 27294522 27389255 |bA145E8.1| NP_055730 0 FALSE 1 5 64 0.2000
22859 LPHN1 latrophilin 1 19p13.2 14305 20973 - NP_001008701;NP_055736;XP_005259875;XP_005259876;XP_006722751;XP_006722752;XP_006722753 NM_001008701;NM_014921;XM_005259818;XM_005259819;XM_006722688;XM_006722689;XM_006722690 ENSP00000340688 O94910 TRUE can 0 0 0 Opisthokonts 4 Signal transduction chr19 14261688 14294414 |CIRL1|LEC2| XP_005259876 0 FALSE 1 10 2932 0.1330
22861 NLRP1 NLR family, pyrin domain containing 1 17p13.2 7364 14374 606636 NP_001028225;NP_055737;NP_127497;NP_127499;NP_127500 NM_001033053;NM_014922;NM_033004;NM_033006;NM_033007 ENSP00000460475 Q9C000 TRUE can 0 0 0 Vertebrates 1 Cell cycle,Development,Regulation of intracellular processes and metabolism,Signal transduction chr17 5418077 5487277 |CARD7|CIDED|CLR17.1|DEFCAP|DEFCAP-L/S|NALP1|PP1044|SLEV1|VAMAS1| NP_127497 0 FALSE 1 16 4876 0.1500 3
22865 SLITRK3 SLIT and NTRK-like family, member 3 3q26.1 18064 23501 609679 NP_055741;XP_005247287 NM_014926;XM_005247230 ENSP00000241274 O94933 TRUE can 0 0 0 Metazoans 0 Cell cycle,Development chr3 164905688 164908618 |NA| NP_055741 0 FALSE 1 1 0 0.0000
22882 ZHX2 zinc fingers and homeoboxes 2 8q24.13 16458 18513 609185 NP_055758;XP_005250893;XP_005250894 NM_014943;XM_005250836;XM_005250837 ENSP00000314709 Q9Y6X8 TRUE can 0 0 0 Metazoans 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr8 123963751 123966261 |AFR1|RAF| NP_055758 0 FALSE 1 14 5566 0.1540
22894 DIS3 DIS3 exosome endoribonuclease and 3-5 exoribonuclease 13q22.1 - 20604 607533 NP_001121698;NP_055768;XP_005266351;XP_006719841 NM_001128226;NM_014953;XM_005266294;XM_006719778 ENSP00000366997 Q9Y2L1 TRUE can 0 0 0 Last Universal Common Ancestor 1 DNA/RNA metabolism and transcription,Regulation of transcription chr13 73333936 73355970 |2810028N01Rik|EXOSC11|KIAA1008|RRP44|dis3p| NP_055768 0 FALSE 1 25 2597 0.2630 6
22906 TRAK1 trafficking protein, kinesin binding 1 3p22.1 9732 29947 608112 NP_001036111;NP_001252537;NP_001252538;NP_001252539;NP_055780;XP_005265013;XP_005265014;XP_005265015;XP_005265016;XP_005265017;XP_005265019;XP_005265020;XP_005265021;XP_006713091;XP_006713092;XP_006713093;XP_006713094 NM_001042646;NM_001265608;NM_001265609;NM_001265610;NM_014965;XM_005264956;XM_005264957;XM_005264958;XM_005264959;XM_005264960;XM_005264962;XM_005264963;XM_005264964;XM_006713028;XM_006713029;XM_006713030;XM_006713031 ENSP00000328998 Q9UPV9 TRUE can 0 0 0 Metazoans 1 Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr3 42132962 42265226 |MILT1|OIP106| NP_001036111 0 FALSE 1 11 447 0.0550 3
22947 DUX4L1 double homeobox 4 like 1 4q35 16189 3082 - NP_149418 NM_033178 - NA TRUE cgc 1 0 20 - 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr4 191012160 191013431 |NA| NP_001120858 20 FALSE 1
22978 NT5C2 5-nucleotidase, cytosolic II 10q24.32 2686 8022 600417 NP_001127845;NP_036361;XP_005269689;XP_005269690;XP_005269691;XP_005269692;XP_005269693;XP_005269694;XP_005269695;XP_005269696;XP_005269697;XP_005269698;XP_005269699;XP_005269700;XP_005269701;XP_005269702;XP_005269703;XP_006717784;XP_006717785;XP_006717786;XP_006717787 NM_001134373;NM_012229;XM_005269632;XM_005269633;XM_005269634;XM_005269635;XM_005269636;XM_005269637;XM_005269638;XM_005269639;XM_005269640;XM_005269641;XM_005269642;XM_005269643;XM_005269644;XM_005269645;XM_005269646;XM_006717721;XM_006717722;XM_006717723;XM_006717724 ENSP00000339479 P49902 TRUE cgc 0 0 0 Last Universal Common Ancestor 3 Cellular metabolism,DNA/RNA metabolism and transcription chr10 104849432 104934715 |GMP|NT5B|PNT5|SPG65|cN-II| XP_005269689 0 FALSE 1 21 1441 0.0760
22982 DIP2C DIP2 disco-interacting protein 2 homolog C (Drosophila) 10p15.3 17200 29150 611380 NP_055789;XP_005252483;XP_005252484;XP_005252485;XP_005252486;XP_005252487 NM_014974;XM_005252426;XM_005252427;XM_005252428;XM_005252429;XM_005252430 ENSP00000280886 Q9Y2E4 TRUE can 0 0 0 Last Universal Common Ancestor 2 -1 chr10 323268 735518 |KIAA0934| XP_005252485 0 FALSE 1 1 0 0.0000
22992 KDM2A lysine (K)-specific demethylase 2A 11q13.2 5741 13606 605657 NP_001243334;NP_036440;XP_006718542;XP_006718543;XP_006718544 NM_001256405;NM_012308;NR_027473;XM_006718479;XM_006718480;XM_006718481 ENSP00000432786 Q9Y2K7 TRUE can 0 0 0 Eukaryotes 5 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr11 66888788 67022523 |CXXC8|FBL11|FBXL11|JHDM1A|LILINA| NP_036440 0 FALSE 1 17 2356 0.1030 3
22998 LIMCH1 LIM and calponin homology domains 1 4p13 11125 29191 - NP_001106188;NP_001106189;NP_001106190;NP_001106191;NP_001276051;NP_001276053;NP_055803;XP_005248114;XP_005248115;XP_005248116;XP_005248117;XP_005248118;XP_005248119;XP_005248120;XP_005248121;XP_005248122;XP_005248123;XP_005248124;XP_005248125;XP_005248126;XP_005248127;XP_005248128;XP_005248129;XP_005248130;XP_005248131;XP_005248132;XP_006714059;XP_006714060;XP_006714061 NM_001112717;NM_001112718;NM_001112719;NM_001112720;NM_001289122;NM_001289124;NM_014988;XM_005248057;XM_005248058;XM_005248059;XM_005248060;XM_005248061;XM_005248062;XM_005248063;XM_005248064;XM_005248065;XM_005248066;XM_005248067;XM_005248068;XM_005248069;XM_005248070;XM_005248071;XM_005248072;XM_005248073;XM_005248074;XM_005248075;XM_006713996;XM_006713997;XM_006713998 ENSP00000316891 Q9UPQ0 TRUE can 0 0 0 Eukaryotes 6 Cellular processes chr4 41362858 41694403 |LIMCH1A|LMO7B| XP_005248114 0 FALSE 1 14 3261 0.2750
22999 RIMS1 regulating synaptic membrane exocytosis 1 6q12-q13 9435 17282 606629 NP_001161879;NP_001161880;NP_001161881;NP_001161882;NP_001161883;NP_055804;XP_005248742;XP_005248743;XP_005248744;XP_005248745;XP_005248747;XP_005248748;XP_006715446;XP_006715447;XP_006715448;XP_006715449;XP_006715450;XP_006715451;XP_006715452;XP_006715453;XP_006715454;XP_006715455 NM_001168407;NM_001168408;NM_001168409;NM_001168410;NM_001168411;NM_014989;XM_005248685;XM_005248686;XM_005248687;XM_005248688;XM_005248690;XM_005248691;XM_006715383;XM_006715384;XM_006715385;XM_006715386;XM_006715387;XM_006715388;XM_006715389;XM_006715390;XM_006715391;XM_006715392 ENSP00000428417 Q86UR5 TRUE can 0 0 0 Metazoans 0 Cell response to stimuli,Cellular metabolism,Cellular processes,Multicellular activities,Signal transduction chr6 72596727 73110413 |CORD7|RAB3IP2|RIM1| NP_055804 0 FALSE 1 25 8770 0.0770 7
23001 WDFY3 WD repeat and FYVE domain containing 3 4q21.23 10304 20751 - NP_055806;XP_005262915;XP_006714214;XP_006714215 NM_014991;NM_178583;NM_178585;XM_005262858;XM_006714151;XM_006714152 ENSP00000295888 Q8IZQ1 TRUE can 0 0 0 Eukaryotes 0 -1 chr4 85594024 85781744 |ALFY|ZFYVE25| XP_005262915 0 FALSE 1 29 11851 0.1580
23024 PDZRN3 PDZ domain containing ring finger 3 3p13 15115 17704 609729 NP_055824;XP_005264775 NM_015009;XM_005264718 ENSP00000263666 Q9UPQ7 TRUE can 0 0 0 Metazoans 0 -1 chr3 73432519 73673976 |LNX3|SEMACAP3| NP_055824 0 FALSE 1 5 470 0.1000
23037 PDZD2 PDZ domain containing 2 5p13.3 10142 18486 610697 NP_835260;XP_005248326;XP_005248327;XP_005248328;XP_005248329;XP_006714519;XP_006714520;XP_006714521;XP_006714522;XP_006714523 NM_015022;NM_178140;XM_005248269;XM_005248270;XM_005248271;XM_005248272;XM_006714456;XM_006714457;XM_006714458;XM_006714459;XM_006714460 ENSP00000282493 O15018 TRUE can 0 0 0 Metazoans 1 -1 chr5 31799356 32108238 |AIPC|PAPIN|PDZK3| XP_005248326 0 FALSE 1 8 1714 0.1070
23042 PDXDC1 pyridoxal-dependent decarboxylase domain containing 1 16p13.11 13789 28995 614244 NP_001272373;NP_001272374;NP_001272376;NP_001272377;NP_001272378;NP_001272379;NP_055842;XP_005255230;XP_005255231;XP_005255233;XP_006720928;XP_006720929 NM_001285444;NM_001285445;NM_001285447;NM_001285448;NM_001285449;NM_001285450;NM_015027;XM_005255173;XM_005255174;XM_005255176;XM_006720865;XM_006720866 ENSP00000379691 Q86XE2 TRUE can 0 0 0 Metazoans 1 Cellular metabolism chr16 15068587 15130129 |LP8165| XP_005255230 0 FALSE 1 15 1292 0.0860
23046 KIF21B kinesin family member 21B 1q32.1 - 29442 608322 NP_001239029;NP_001239031;NP_001239032;NP_060066 NM_001252100;NM_001252102;NM_001252103;NM_017596 ENSP00000328494 O75037 TRUE can 0 0 0 Eukaryotes 1 Cellular processes chr1 200943226 200992511 |NA| NP_001239029 0 FALSE 1 4 218 0.0000
23048 FNBP1 formin binding protein 1 9q34 10446 17069 606191 NP_055848;XP_005251872;XP_005251873;XP_005251874;XP_005251875;XP_005251876;XP_005251877;XP_005251878;XP_005251879;XP_005251880;XP_005251881;XP_005251882;XP_005251883;XP_005251884;XP_005251885;XP_005251886;XP_005251887;XP_005251888;XP_005251889;XP_005251890;XP_005251891;XP_006717079;XP_006717080 NM_015033;XM_005251815;XM_005251816;XM_005251817;XM_005251818;XM_005251819;XM_005251820;XM_005251821;XM_005251822;XM_005251823;XM_005251824;XM_005251825;XM_005251826;XM_005251827;XM_005251828;XM_005251829;XM_005251830;XM_005251831;XM_005251832;XM_005251833;XM_005251834;XM_006717016;XM_006717017 ENSP00000413625 Q96RU3 TRUE cgc 1 0 0 Eukaryotes 7 Cellular processes chr9 132658100 132757237 |FBP17| XP_005251872 0 FALSE 1 29 10883 0.0710
23072 HECW1 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1 7p13 - 22195 610384 NP_001273988;NP_055867;XP_005249722;XP_006715733;XP_006715734;XP_006715735;XP_006715736 NM_001287059;NM_015052;XM_005249665;XM_006715670;XM_006715671;XM_006715672;XM_006715673 ENSP00000379228 Q76N89 TRUE can 0 0 0 Eukaryotes 0 Cellular metabolism,Cellular processes chr7 43351362 43601522 |NEDL1| XP_005249722 0 FALSE 1 13 1116 0.0900 2
23077 MYCBP2 MYC binding protein 2, E3 ubiquitin protein ligase 13q22 10104 23386 610392 NP_055872;XP_005266356;XP_005266357;XP_006719842;XP_006719843;XP_006719844;XP_006719845;XP_006719846;XP_006719847;XP_006719848;XP_006719849;XP_006719850;XP_006719851;XP_006719852 NM_015057;XM_005266299;XM_005266300;XM_006719779;XM_006719780;XM_006719781;XM_006719782;XM_006719783;XM_006719784;XM_006719785;XM_006719786;XM_006719787;XM_006719788;XM_006719789 ENSP00000384288 O75592 TRUE can 0 0 0 Eukaryotes 1 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr13 77619516 77900910 |NA| XP_005266356 0 FALSE 1 27 4579 0.1250
23085 ERC1 ELKS/RAB6-interacting/CAST family member 1 12p13.3 6181 17072 607127 NP_829883;NP_829884 NM_178039;NM_178040;NR_027946;NR_027948;NR_027949 ENSP00000354158 Q8IUD2 TRUE cgc 1 0 0 Eukaryotes 5 Cell cycle,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction chr12 1137070 1599393 |Cast2|ELKS|ERC-1|RAB6IP2| NP_829884 0 FALSE 1 33 10018 0.0870 1
23086 EXPH5 exophilin 5 11q22.3 8341 30578 612878 NP_055880;XP_005271518;XP_005271519;XP_005271520 NM_001144763;NM_001144765;NM_015065;XM_005271461;XM_005271462;XM_005271463 ENSP00000265843 Q149M6 TRUE can 0 0 0 Vertebrates 0 Cellular processes chr11 108380267 108464263 |SLAC2-B|SLAC2B| NP_055880 0 FALSE 1 4 994 0.0000
23092 ARHGAP26 Rho GTPase activating protein 26 5q31 5643 17073 605370 NP_001129080;NP_055886;XP_005268455;XP_005268456;XP_005268457;XP_005268459;XP_005268460;XP_006714831;XP_006714832;XP_006714833;XP_006714834;XP_006714835;XP_006714836;XP_006714837 NM_001135608;NM_015071;XM_005268398;XM_005268399;XM_005268400;XM_005268402;XM_005268403;XM_006714768;XM_006714769;XM_006714770;XM_006714771;XM_006714772;XM_006714773;XM_006714774 ENSP00000274498 Q9UNA1 TRUE cgc 1 0 0 Opisthokonts 0 Cellular processes,Development,Signal transduction chr5 142150658 142602008 |GRAF|GRAF1|OPHN1L|OPHN1L1| XP_005268455 0 FALSE 1 10 930 0.1110
23095 KIF1B kinesin family member 1B 1p36.2 5818 16636 605995 NP_055889;NP_904325 NM_015074;NM_183416 ENSP00000263934 O60333 TRUE can 0 0 0 Eukaryotes 10 Cellular processes,Multicellular activities chr1 10292387 10436642 |CMT2A1|HMSNII|KLP|NBLST1| NP_055889 0 FALSE 1 32 21861 0.0580
23111 SPG20 spastic paraplegia 20 (Troyer syndrome) 13q13.3 6170 18514 607111 NP_001135766;NP_001135767;NP_001135768;NP_055902;XP_005266370;XP_005266371;XP_005266372;XP_005266373;XP_005266374 NM_001142294;NM_001142295;NM_001142296;NM_015087;XM_005266313;XM_005266314;XM_005266315;XM_005266316;XM_005266317 ENSP00000347314 Q8N0X7 TRUE can 0 0 0 Eukaryotes 3 -1 chr13 36878505 36909967 |SPARTIN|TAHCCP1| NP_001135766 0 FALSE 1 32 3190 0.1390 1
23122 CLASP2 cytoplasmic linker associated protein 2 3p22.3 12054 17078 605853 NP_001193973;NP_055912;XP_006713099;XP_006713100;XP_006713101;XP_006713102;XP_006713103;XP_006713104;XP_006713105;XP_006713106;XP_006713107;XP_006713108;XP_006713109;XP_006713110;XP_006713111;XP_006713112;XP_006713113;XP_006713114;XP_006713115;XP_006713116;XP_006713117;XP_006713118;XP_006713119;XP_006713120;XP_006713121;XP_006713122;XP_006713123 NM_001207044;NM_015097;XM_006713036;XM_006713037;XM_006713038;XM_006713039;XM_006713040;XM_006713041;XM_006713042;XM_006713043;XM_006713044;XM_006713045;XM_006713046;XM_006713047;XM_006713048;XM_006713049;XM_006713050;XM_006713051;XM_006713052;XM_006713053;XM_006713054;XM_006713055;XM_006713056;XM_006713057;XM_006713058;XM_006713059;XM_006713060 ENSP00000419974 O75122 TRUE can 0 0 0 Eukaryotes 1 Cell cycle,Cellular metabolism,Cellular processes,Development,Regulation of intracellular processes and metabolism chr3 33540126 33759494 |NA| NP_055912 0 FALSE 1 23 9008 0.0870 7
23129 PLXND1 plexin D1 3q22.1 5046 9107 604282 NP_055918 NM_015103 ENSP00000317128 Q9Y4D7 TRUE can 0 0 0 Eukaryotes 2 Signal transduction chr3 129275158 129325482 |PLEXD1| NP_055918 0 FALSE 1 4 14853 0.0000 4
23130 ATG2A autophagy related 2A 11q13.1 17186 29028 - NP_055919;XP_005273906;XP_005273907 NM_015104;XM_005273849;XM_005273850 ENSP00000366475 Q2TAZ0 TRUE can 0 0 0 Eukaryotes 0 -1 chr11 64662448 64684607 |NA| NP_055919 0 FALSE 1 15 1475 0.0760
23136 EPB41L3 erythrocyte membrane protein band 4.1-like 3 18p11.32 5622 3380 605331 NP_001268462;NP_001268463;NP_001268464;NP_036439;XP_005258142;XP_005258143;XP_005258144;XP_005258145;XP_005258146;XP_005258147;XP_005258148;XP_006722364;XP_006722365;XP_006722366;XP_006722367;XP_006722368;XP_006722369;XP_006722370;XP_006722371;XP_006722372;XP_006722373;XP_006722374;XP_006722375;XP_006722376;XP_006722377;XP_006722378;XP_006722379 NM_001281533;NM_001281534;NM_001281535;NM_012307;XM_005258085;XM_005258086;XM_005258087;XM_005258088;XM_005258089;XM_005258090;XM_005258091;XM_006722301;XM_006722302;XM_006722303;XM_006722304;XM_006722305;XM_006722306;XM_006722307;XM_006722308;XM_006722309;XM_006722310;XM_006722311;XM_006722312;XM_006722313;XM_006722314;XM_006722315;XM_006722316 ENSP00000341138 Q9Y2J2 TRUE can 0 0 0 Metazoans 1 Cellular processes chr18 5394685 5489182 |4.1B|DAL-1|DAL1| NP_036439 0 FALSE 1 34 18134 0.1530
23140 ZZEF1 zinc finger, ZZ-type with EF-hand domain 1 17p13.2 15906 29027 - NP_055928;XP_005256617;XP_005256618;XP_005256619;XP_006721548;XP_006721549 NM_015113;XM_005256560;XM_005256561;XM_005256562;XM_006721485;XM_006721486;XR_429813 ENSP00000371051 O43149 TRUE can 0 0 0 Eukaryotes 0 Cell cycle chr17 3912087 4046189 |ZZZ4| XP_005256617 0 FALSE 1 11 332 0.0360
23141 ANKLE2 ankyrin repeat and LEM domain containing 2 12q24.33 - 29101 616062 NP_055929;XP_005266216;XP_005266217;XP_005266218;XP_006719798 NM_015114;XM_005266159;XM_005266160;XM_005266161;XM_006719735 ENSP00000350686 Q86XL3 TRUE can 0 0 0 Metazoans 2 -1 chr12 133303831 133338384 |KIAA0692|LEMD7|Lem4| NP_055929 0 FALSE 1 7 94 0.3330 1
23152 CIC capicua transcriptional repressor 19q13.2 10831 14214 612082 NP_055940;XP_005258730;XP_005258731;XP_005258732 NM_015125;XM_005258673;XM_005258674;XM_005258675 ENSP00000160740 Q96RK0 TRUE cgc 0 1 0 Opisthokonts 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr19 42788857 42799340 |NA| NP_055940 0 FALSE 2 14 2687 0.0330
23157 SEPT6 septin 6 Xq24 6716 15848 300683 NP_055944;NP_665798;NP_665799;NP_665801;XP_005262457;XP_006724811;XP_006724812;XP_006724813 NM_015129;NM_145799;NM_145800;NM_145802;XM_005262400;XM_006724748;XM_006724749;XM_006724750 ENSP00000341524 Q14141 TRUE cgc 1 0 1 Eukaryotes 2 -1 chrX 118753884 118809631 |NA| XP_005262457 1 FALSE 1 21 3530 0.0950 2
23180 RFTN1 raftlin, lipid raft linker 1 3p24.3 17950 30278 - NP_055965;XP_005265042;XP_005265043;XP_005265044;XP_005265045;XP_006713132;XP_006713133;XP_006713134 NM_015150;XM_005264985;XM_005264986;XM_005264987;XM_005264988;XM_006713069;XM_006713070;XM_006713071 ENSP00000334153 Q14699 TRUE can 0 0 0 Vertebrates 0 -1 chr3 16358338 16535376 |PIB10|RAFTLIN| NP_055965 0 FALSE 1
23191 CYFIP1 cytoplasmic FMR1 interacting protein 1 15q11 5890 13759 606322 NP_001028200;NP_001274739;NP_055423;XP_005272600 NM_001033028;NM_001287810;NM_014608;XM_005272543 ENSP00000245479;ENSP00000324549;ENSP00000337513;ENSP00000353769;ENSP00000439856 Q7L576 TRUE can 0 0 1 Eukaryotes 1 Cell cycle,Development,Regulation of intracellular processes and metabolism chr15 22925783 23003037 |P140SRA-1|SHYC|SRA-1| NP_001274739 1 FALSE 1 39 10226 0.0890 11
23217 ZFR2 zinc finger RNA binding protein 2 19p13.3 - 29189 - NP_001139112;NP_055989 NM_001145640;NM_015174;NR_027149 ENSP00000262961 Q9UPR6 TRUE can 0 0 0 Metazoans 0 -1 chr19 3805950 3869015 |KIAA1086| NP_055989 0 FALSE 1
23224 SYNE2 spectrin repeat containing, nuclear envelope 2 14q23.2 9763 17084 608442 NP_055995;NP_878914;NP_878917;NP_878918;XP_005267511;XP_005267512;XP_005267513;XP_005267514;XP_005267515;XP_005267516;XP_005267517;XP_006720147 NM_015180;NM_182910;NM_182912;NM_182913;NM_182914;XM_005267454;XM_005267455;XM_005267456;XM_005267457;XM_005267458;XM_005267459;XM_005267460;XM_006720084 ENSP00000350719 Q8WXH0 TRUE can 0 0 0 Eukaryotes 11 -1 chr14 64375867 64692241 |EDMD5|NUA|NUANCE|Nesp2|Nesprin-2|SYNE-2|TROPH| XP_005267511 0 FALSE 3 24 3793 0.0800 1
23251 KIAA1024 KIAA1024 15q25.1 17206 29172 - NP_056021;XP_006720504 NM_015206;XM_006720441 ENSP00000307461 Q9UPX6 TRUE can 0 0 0 Vertebrates 1 -1 chr15 79748490 79760723 |NA| NP_056021 0 FALSE 1
23261 CAMTA1 calmodulin binding transcription activator 1 1p36.31-p36.23 16681 18806 611501 NP_001182492;NP_001229630;NP_056030;XP_006710545;XP_006710546;XP_006710547 NM_001195563;NM_001242701;NM_015215;NR_038934;XM_006710482;XM_006710483;XM_006710484 ENSP00000306522 Q9Y6Y1 TRUE cgc 1 0 0 Eukaryotes 6 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr1 6845591 7812591 |CANPMR| NP_056030 0 FALSE 2 1 0 0.0000 1
23266 LPHN2 latrophilin 2 1p31.1 6116 18582 607018 NP_036434;XP_005270723;XP_005270724;XP_005270725;XP_005270727;XP_005270730;XP_005270731;XP_006710548;XP_006710549;XP_006710550;XP_006710551;XP_006710552;XP_006710553;XP_006710554;XP_006710555;XP_006710556;XP_006710557;XP_006710558;XP_006710559;XP_006710560 NM_012302;XM_005270666;XM_005270667;XM_005270668;XM_005270670;XM_005270673;XM_005270674;XM_006710485;XM_006710486;XM_006710487;XM_006710488;XM_006710489;XM_006710490;XM_006710491;XM_006710492;XM_006710493;XM_006710494;XM_006710495;XM_006710496;XM_006710497 ENSP00000322270 O95490 TRUE can 0 0 0 Opisthokonts 4 Signal transduction chr1 82302670 82456826 |CIRL2|LEC1|LPHH1| XP_005270723 0 FALSE 1 4 83 0.1670
23269 MGA MGA, MAX dimerization protein 15q14 - 14010 616061 NP_001074010;NP_001157745;XP_005254300;XP_005254301;XP_005254302;XP_005254303;XP_005254304;XP_005254305;XP_005254306;XP_005254309;XP_005254310;XP_005254311;XP_006720505;XP_006720506;XP_006720507;XP_006720508 NM_001080541;NM_001164273;XM_005254243;XM_005254244;XM_005254245;XM_005254246;XM_005254247;XM_005254248;XM_005254249;XM_005254252;XM_005254253;XM_005254254;XM_006720442;XM_006720443;XM_006720444;XM_006720445 ENSP00000219905;ENSP00000447378 Q8IWI9 TRUE can 0 0 0 Last Universal Common Ancestor 2 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr15 41961093 42059475 |MAD5|MXD5| XP_005254300 0 FALSE 2 20 1619 0.2000 1
23281 MTUS2 microtubule associated tumor suppressor candidate 2 13q12.3 11108 20595 - NP_001028774;NP_056048 NM_001033602;NM_015233 ENSP00000392057 Q5JR59 TRUE can 0 0 0 Metazoans 4 -1 chr13 29598806 30077340 |CAZIP|KIAA0774|TIP150| NP_001028774 0 FALSE 2 164 180197 0.0070
23284 LPHN3 latrophilin 3 4q13.1 10055 20974 - NP_056051;XP_006714216;XP_006714217;XP_006714218;XP_006714219 NM_015236;XM_006714153;XM_006714154;XM_006714155;XM_006714156 ENSP00000422533;ENSP00000459568 Q9HAR2 TRUE can 0 0 0 Opisthokonts 0 Signal transduction chr4 62363012 62936623 |CIRL3|LEC3| NP_056051 0 FALSE 2 1 0 0.0000
23305 ACSL6 acyl-CoA synthetase long-chain family member 6 5q31.1 9190 16496 604443 NP_001009185;NP_001192176;NP_001192177;NP_001192179;NP_001192180;NP_056071;XP_006714642;XP_006714643;XP_006714644 NM_001009185;NM_001205247;NM_001205248;NM_001205250;NM_001205251;NM_015256;XM_006714579;XM_006714580;XM_006714581 ENSP00000296869 Q9UKU0 TRUE cgc 1 0 0 Last Universal Common Ancestor 1 Cell cycle,Cellular metabolism,Development chr5 131289930 131347246 |FACL6|LACS 6|LACS5| NP_001009185 0 FALSE 1 2 9 0.0000
23314 SATB2 SATB homeobox 2 2q33 12178 21637 608148 NP_001165980;NP_001165988;NP_056080;XP_005246453;XP_006712435 NM_001172509;NM_001172517;NM_015265;XM_005246396;XM_006712372 ENSP00000260926 Q9UPW6 TRUE can 0 0 0 Metazoans 2 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr2 200136937 200320760 |GLSS| NP_001165980 0 FALSE 1 7 929 0.1430
23345 SYNE1 spectrin repeat containing, nuclear envelope 1 6q25 9762 17089 608441 NP_149062;NP_892006;XP_006715470;XP_006715471;XP_006715472;XP_006715473;XP_006715474;XP_006715475;XP_006715476;XP_006715477;XP_006715478;XP_006715479;XP_006715480;XP_006715481;XP_006715482;XP_006715483;XP_006715484;XP_006715485;XP_006715486;XP_006715487;XP_006715488 NM_001099267;NM_001134379;NM_015293;NM_033071;NM_133650;NM_182961;XM_006715407;XM_006715408;XM_006715409;XM_006715410;XM_006715411;XM_006715412;XM_006715413;XM_006715414;XM_006715415;XM_006715416;XM_006715417;XM_006715418;XM_006715419;XM_006715420;XM_006715421;XM_006715422;XM_006715423;XM_006715424;XM_006715425 ENSP00000356224 Q8NF91 TRUE can 0 0 0 Eukaryotes 11 Cellular processes,Development chr6 152477044 152949466 |8B|ARCA1|C6orf98|CPG2|EDMD4|MYNE1|Nesp1|SCAR8|dJ45H2.2| NP_892006 0 FALSE 3 24 3918 0.0760 1
23365 ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12 11q23.3 9207 14193 604763 NP_001185594;NP_056128;XP_005271535;XP_005271537;XP_006718868 NM_001198665;NM_015313;XM_005271478;XM_005271480;XM_006718805 ENSP00000380942 Q9NZN5 TRUE cgc 1 0 0 Eukaryotes 1 Signal transduction chr11 120278445 120355215 |LARG|PRO2792| NP_056128 0 FALSE 1 15 2407 0.0760 3
23373 CRTC1 CREB regulated transcription coactivator 1 19p13.11 6339 16062 607536 NP_001091952;NP_056136;XP_005259890;XP_005259891;XP_005259892;XP_005259893;XP_006722773 NM_001098482;NM_015321;NM_025021;XM_005259833;XM_005259834;XM_005259835;XM_005259836;XM_006722710 ENSP00000345001 Q6UUV9 TRUE cgc 1 0 1 Metazoans 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr19 18794513 18888189 |MECT1|TORC-1|TORC1|WAMTP1| NP_001091952 1 FALSE 2 7 477 0.3810
23385 NCSTN nicastrin 1q22-q23 5584 17091 605254 NP_056146;XP_005245110 NM_015331;XM_005245053 ENSP00000294785 Q92542 TRUE can 0 0 0 Eukaryotes 1 Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism,Signal transduction chr1 160313187 160328058 |ATAG1874| NP_056146 0 FALSE 1 84 42641 0.1040 12
23399 CTDNEP1 CTD nuclear envelope phosphatase 1 17p13 16845 19085 610684 NP_001137247;NP_056158 NM_001143775;NM_015343 ENSP00000321732 O95476 TRUE can 0 0 2 Eukaryotes 3 Cellular processes chr17 7147507 7154615 |DULLARD|HSA011916|NET56| NP_001137247 2 FALSE 1 3 494 0.0000
23405 DICER1 dicer 1, ribonuclease type III 14q32.13 5875 17098 606241 NP_001182502;NP_001258211;NP_085124;NP_803187 NM_001195573;NM_001271282;NM_030621;NM_177438 ENSP00000343745 Q9UPY3 TRUE cgc 0 1 0 Last Universal Common Ancestor 19 Cell cycle,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription chr14 95556838 95599795 |Dicer|Dicer1e|HERNA|RMSE2| NP_001258211 0 FALSE 1 45 24870 0.0980 10
23451 SF3B1 splicing factor 3b, subunit 1, 155kDa 2q33.1 9281 10768 605590 NP_001005526;NP_036565;XP_005246485 NM_001005526;NM_012433;XM_005246428;XR_241300;XR_241301;XR_241302 ENSP00000335321 O75533 TRUE cgc 1 0 0 Eukaryotes 0 DNA/RNA metabolism and transcription,Development,Regulation of transcription chr2 198257030 198288699 |Hsh155|PRP10|PRPF10|SAP155|SF3b155| NP_036565 0 FALSE 4 134 29532 0.1830 16
23462 HEY1 hes-related family bHLH transcription factor with YRPW motif 1 8q21 4260 4880 602953 NP_001035798;NP_001269780;NP_036390 NM_001040708;NM_001282851;NM_012258 ENSP00000338272 Q9Y5J3 TRUE cgc 1 0 0 Metazoans 2 Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction chr8 80677426 80679898 |BHLHb31|CHF2|HERP2|HESR1|HRT-1|OAF1|hHRT1| NP_001035798 0 FALSE 1 14 2417 0.1320
23469 PHF3 PHD finger protein 3 6q12 8477 8921 607789 NP_055968;XP_005248758;XP_005248759;XP_005248760;XP_006715489;XP_006715490 NM_015153;XM_005248701;XM_005248702;XM_005248703;XM_006715426;XM_006715427 ENSP00000262043 Q92576 TRUE can 0 0 0 Eukaryotes 4 Cellular metabolism,DNA/RNA metabolism and transcription chr6 64356457 64423601 |NA| NP_055968 0 FALSE 1 5 90 0.0000
23476 BRD4 bromodomain containing 4 19p13.1 10574 13575 608749 NP_055114;NP_490597 NM_014299;NM_058243 ENSP00000263377 O60885 TRUE cgc 1 0 0 Eukaryotes 1 -1 chr19 15349191 15383910 |HUNK1|HUNKI| NP_490597 0 FALSE 1 62 31507 0.0790 8
23499 MACF1 microtubule-actin crosslinking factor 1 1p32-p31 9750 13664 608271 NP_036222;XP_005270751;XP_005270752;XP_005270753;XP_005270754;XP_005270755;XP_005270757;XP_006710582;XP_006710583;XP_006710584;XP_006710585;XP_006710586;XP_006710587;XP_006710588;XP_006710589;XP_006710590;XP_006710591;XP_006710592;XP_006710593;XP_006710594;XP_006710595;XP_006710596;XP_006710597;XP_006710598;XP_006710599;XP_006710600;XP_006710601;XP_006710602;XP_006710603 NM_012090;NM_033044;XM_005270694;XM_005270695;XM_005270696;XM_005270697;XM_005270698;XM_005270700;XM_006710519;XM_006710520;XM_006710521;XM_006710522;XM_006710523;XM_006710524;XM_006710525;XM_006710526;XM_006710527;XM_006710528;XM_006710529;XM_006710530;XM_006710531;XM_006710532;XM_006710533;XM_006710534;XM_006710535;XM_006710536;XM_006710537;XM_006710538;XM_006710539;XM_006710540 ENSP00000354573 Q9UPN3 TRUE can 0 0 0 Eukaryotes 5 Cell cycle chr1 39734370 39951463 |ABP620|ACF7|MACF| XP_005270751 0 FALSE 2 47 45118 0.0480
23504 RIMBP2 RIMS binding protein 2 12q24.33 17183 30339 611602 NP_056162 NM_015347 ENSP00000261655 O15034 TRUE can 0 0 0 Eukaryotes 0 -1 chr12 130884224 130963558 |PPP1R133|RIM-BP2| NP_056162 0 FALSE 1 3 222 0.0000
23512 SUZ12 SUZ12 polycomb repressive complex 2 subunit 17q11.2 6949 17101 606245 NP_056170;XP_005258011;XP_006721857 NM_015355;XM_005257954;XM_006721794;XR_243773 ENSP00000316578 Q15022 TRUE cgc 1 0 0 Eukaryotes 7 Cell cycle,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr17 30264266 30326019 |CHET9|JJAZ1| NP_056170 0 FALSE 3 322 206908 0.0410 13
23522 KAT6B K(lysine) acetyltransferase 6B 10q22.2 7065 17582 605880 NP_001243397;NP_001243398;NP_036462;XP_005269721 NM_001256468;NM_001256469;NM_012330;XM_005269664 ENSP00000287239 Q8WYB5 TRUE cgc 1 0 0 Eukaryotes 3 Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr10 76602616 76790801 |GTPTS|MORF|MOZ2|MYST4|ZC2HC6B|qkf|querkopf| NP_036462 0 FALSE 1 6 78 0.0000 1
23533 PIK3R5 phosphoinositide-3-kinase, regulatory subunit 5 17p13.1 11433 30035 611317 NP_001136105;NP_001238780;NP_001238781;NP_001238782;NP_001238784;NP_055123;XP_005256636;XP_005256637 NM_001142633;NM_001251851;NM_001251852;NM_001251853;NM_001251855;NM_014308;XM_005256579;XM_005256580 ENSP00000392812 Q8WYR1 TRUE can 0 0 0 Vertebrates 0 -1 chr17 8783959 8814811 |F730038I15Rik|FOAP-2|P101-PI3K|p101| NP_001136105 0 FALSE 1 7 4647 0.0480 1
23592 LEMD3 LEM domain containing 3 12q14 9704 28887 607844 NP_001161086;NP_055134 NM_001167614;NM_014319 ENSP00000308369 Q9Y2U8 TRUE can 0 0 0 Eukaryotes 5 -1 chr12 65563377 65640102 |MAN1| NP_055134 0 FALSE 1 9 715 0.1670 1
23598 PATZ1 POZ (BTB) and AT hook containing zinc finger 1 22q12.2 5522 13071 605165 NP_055138;NP_114439;NP_114440;NP_114441 NM_014323;NM_032050;NM_032051;NM_032052 ENSP00000266269 Q9HBE1 TRUE cgc 1 0 0 Eukaryotes 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr22 31722880 31741588 |MAZR|PATZ|RIAZ|ZBTB19|ZNF278|ZSG|dJ400N23| NP_055138 0 FALSE 1 9 364 0.1670
23619 ZIM2 zinc finger, imprinted 2 19q13.4 10321 12875 - NP_001139798;NP_001139799;NP_056178 NM_001146326;NM_001146327;NM_015363 ENSP00000221722;ENSP00000326581 Q9NZV7 TRUE can 0 0 0 Eukaryotes 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr19 57325046 57336023 |ZNF656| NP_001139656 0 FALSE 1
23624 CBLC Cbl proto-oncogene C, E3 ubiquitin protein ligase 19q13.2 9765 15961 608453 NP_001124324;NP_036248;XP_005258753;XP_005258754 NM_001130852;NM_012116;XM_005258696;XM_005258697;XR_243917 ENSP00000270279 Q9ULV8 TRUE cgc 0 1 0 Mammals 1 Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism,Signal transduction chr19 45281189 45303697 |CBL-SL|RNF57| NP_036248 0 FALSE 2 37 7008 0.1290
23742 NPAP1 nuclear pore associated protein 1 15q11-q13 8506 1190 610922 NP_061831 NM_018958 ENSP00000333735 Q9NZP6 TRUE can 0 0 0 Mammals 0 Development,Multicellular activities chr15 24921015 24924482 |C15orf2| NP_061831 0 FALSE 1
25791 NGEF neuronal guanine nucleotide exchange factor 2q37 10442 7807 605991 NP_001107562;NP_062824 NM_001114090;NM_019850 ENSP00000264051 Q8N5V2 TRUE can 0 0 0 Eukaryotes 0 Development,Signal transduction chr2 233744202 233839600 |ARHGEF27|EPHEXIN| NP_062824 0 FALSE 1 15 707 0.0290
25893 TRIM58 tripartite motif containing 58 1q44 - 24150 - NP_056246 NM_015431 ENSP00000355437 Q8NG06 TRUE can 0 0 0 Eukaryotes 1 -1 chr1 248020549 248039788 |BIA2| NP_056246 0 FALSE 1 5 182 0.2000
25901 CCDC28A coiled-coil domain containing 28A 6q23.1-q24.1 9857 21098 615353 NP_056254 NM_015439 ENSP00000332716 Q8IWP9 TRUE can 0 0 0 Metazoans 5 -1 chr6 139094812 139113937 |C6orf80|CCRL1AP| NP_056254 0 FALSE 1 8 1417 0.0360
25913 POT1 protection of telomeres 1 7q31.33 7572 17284 606478 NP_001036059;NP_056265;XP_006715980 NM_001042594;NM_015450;NR_003102;NR_003103;NR_003104;XM_006715917 ENSP00000350249 Q9NUX5 TRUE cgc 0 0 0 Eukaryotes 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism chr7 124464019 124532434 |CMM10|HPOT1| NP_056265 0 FALSE 1 199 320683 0.0240 11
25914 RTTN rotatin 18q22.2 11525 18654 610436 NP_775901;XP_005266736;XP_006722497;XP_006722498 NM_173630;XM_005266679;XM_006722434;XM_006722435;XR_430072 ENSP00000255674 Q86VV8 TRUE can 0 0 0 Metazoans 0 -1 chr18 67671390 67872552 |NA| NP_775901 0 FALSE 1 1 0 0.0000
25925 ZNF521 zinc finger protein 521 18q11.2 18350 24605 610974 NP_056276;XP_005258298;XP_006722499;XP_006722500 NM_015461;XM_005258241;XM_006722436;XM_006722437 ENSP00000354794 Q96K83 TRUE cgc 1 0 0 Eukaryotes 2 -1 chr18 22669429 22930910 |EHZF|Evi3| NP_056276 0 FALSE 2 7 1211 0.1900
25937 WWTR1 WW domain containing transcription regulator 1 3q23-q24 9580 24042 607392 NP_001161750;NP_001161752;NP_056287 NM_001168278;NM_001168280;NM_015472 ENSP00000353847 Q9GZV5 TRUE cgc 1 0 0 Eukaryotes 2 Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription chr3 149238595 149375093 |NA| NP_001161750 0 FALSE 1 29 3305 0.0910 10
25939 SAMHD1 SAM domain and HD domain 1 20pter-q12 8418 15925 606754 NP_056289;XP_005260441 NM_015474;XM_005260384 ENSP00000262878 Q9Y3Z3 TRUE can 0 0 0 Last Universal Common Ancestor 3 -1 chr20 35521338 35580046 |CHBL2|DCIP|HDDC1|MOP-5|SBBI88| NP_056289 0 FALSE 1 43 11198 0.1920
25942 SIN3A SIN3 transcription regulator family member A 15q24.2 9690 19353 607776 NP_001138829;NP_001138830;NP_056292;XP_006720528;XP_006720529;XP_006720530 NM_001145357;NM_001145358;NM_015477;XM_006720465;XM_006720466;XM_006720467 ENSP00000353622 Q96ST3 TRUE can 0 0 0 Eukaryotes 3 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr15 75664323 75722716 |NA| NP_001138829 0 FALSE 1 186 109744 0.0770 60
25953 PNKD paroxysmal nonkinesigenic dyskinesia 2q35 11369 9153 609023 NP_001070867;NP_056303;NP_072094 NM_001077399;NM_015488;NM_022572 ENSP00000273077 Q8N490 TRUE can 0 0 0 Last Universal Common Ancestor 0 -1 chr2 219135259 219209701 |BRP17|DYT8|FPD1|KIPP1184|MR-1|PKND1|TAHCCP2| NP_056303 0 FALSE 1 7 910 0.0950
25978 CHMP2B charged multivesicular body protein 2B 3p11.2 13174 24537 609512 NP_001231573;NP_054762 NM_001244644;NM_014043 ENSP00000263780 Q9UQN3 TRUE can 0 0 0 Eukaryotes 3 Cellular processes chr3 87289848 87302969 |ALS17|CHMP2.5|VPS2-2|VPS2B| NP_054762 0 FALSE 1 16 2339 0.0330 3
25988 HINFP histone H4 transcription factor 11q23.3 - 17850 607099 NP_001230188;NP_056332;NP_945322;XP_006718876;XP_006718877 NM_001243259;NM_015517;NM_198971;XM_006718813;XM_006718814 ENSP00000318085 Q9BQA5 TRUE can 0 0 0 Metazoans 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr11 118997655 119005205 |HiNF-P|MIZF|ZNF743| NP_056332 0 FALSE 1 38 10944 0.0440
26005 C2CD3 C2 calcium-dependent domain containing 3 11q13.4 16811 24564 615944 NP_001273506;NP_056346;XP_005273950;XP_005273952;XP_005273953;XP_005273954;XP_006718558 NM_001286577;NM_015531;XM_005273893;XM_005273895;XM_005273896;XM_005273897;XM_006718495 ENSP00000323339 Q4AC94 TRUE can 0 0 0 Opisthokonts 1 -1 chr11 73724433 73881837 |OFD14| XP_005273950 0 FALSE 1 6
26038 CHD5 chromodomain helicase DNA binding protein 5 1p36.31 10828 16816 610771 NP_056372 NM_015557 ENSP00000240874;ENSP00000262450;ENSP00000327716;ENSP00000362330 Q8TDI0 TRUE can 0 0 0 Last Universal Common Ancestor 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr1 6166456 6240083 |CHD-5| NP_056372 0 FALSE 1 3 27 0.3330
26039 SS18L1 synovial sarcoma translocation gene on chromosome 18-like 1 20q13.3 9398 15592 606472 NP_945173;XP_005260446;XP_005260448;XP_006723834 NM_015558;NM_198935;XM_005260389;XM_005260391;XM_006723771 ENSP00000333012 O75177 TRUE cgc 1 0 0 Eukaryotes 0 -1 chr20 60718877 60749784 |CREST|LP2261| XP_005260446 0 FALSE 1 34 22348 0.0620
26040 SETBP1 SET binding protein 1 18q21.1 10224 15573 611060 NP_001123582;NP_056374;XP_005258300;XP_005258301;XP_006722501 NM_001130110;NM_015559;XM_005258243;XM_005258244;XM_006722438 ENSP00000282030 Q9Y6X0 TRUE cgc 1 0 0 Eukaryotes 0 -1 chr18 42281312 42643660 |SEB| NP_056374 0 FALSE 1 10 58524 0.0890
26047 CNTNAP2 contactin associated protein-like 2 7q35 5197 13830 604569 NP_054860;XP_006715982 NM_014141;XM_006715919 ENSP00000354778 Q9UHC6 TRUE can 0 0 0 Eukaryotes 2 Multicellular activities,Signal transduction chr7 146471359 148112705 |AUTS15|CASPR2|CDFE|PTHSL1| NP_054860 0 TRUE 3 9 735 0.0000 1
26050 SLITRK5 SLIT and NTRK-like family, member 5 13q31.2 - 20295 609680 NP_056382;XP_005254095;XP_005254096 NM_015567;XM_005254038;XM_005254039 ENSP00000366283 O94991 TRUE can 0 0 0 Metazoans 0 -1 chr13 88327644 88330517 |LRRC11|bA364G4.2| NP_056382 0 FALSE 1
26058 GIGYF2 GRB10 interacting GYF protein 2 2q37.1 - 11960 612003 NP_001096616;NP_001096617;NP_001096618;NP_056390 NM_001103146;NM_001103147;NM_001103148;NM_015575;NR_103492;NR_103493;NR_103494;NR_103495 ENSP00000387170 Q6Y7W6 TRUE can 0 0 0 Eukaryotes 1 -1 chr2 233599908 233721567 |GYF2|PARK11|PERQ2|PERQ3|TNRC15| NP_001096617 0 FALSE 2 52 9316 0.1200
26137 ZBTB20 zinc finger and BTB domain containing 20 3q13.2 5822 13503 606025 NP_001157814;NP_001157815;NP_001157816;NP_001157817;NP_001157818;NP_001157819;NP_056457;XP_005247396;XP_005247397;XP_005247398;XP_005247399;XP_005247400;XP_006713640;XP_006713641;XP_006713642;XP_006713643;XP_006713644 NM_001164342;NM_001164343;NM_001164344;NM_001164345;NM_001164346;NM_001164347;NM_015642;XM_005247339;XM_005247340;XM_005247341;XM_005247342;XM_005247343;XM_006713577;XM_006713578;XM_006713579;XM_006713580;XM_006713581 ENSP00000419153 Q9HC78 TRUE can 0 0 0 Eukaryotes 3 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr3 114057855 114099253 |DPZF|HOF|ODA-8S|PRIMS|ZNF288| NP_001157814 0 FALSE 1 7 527 0.3810
26191 PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid) 1p13.2 6100 9652 600716 NP_001180360;NP_036543;NP_057051;XP_005270795 NM_001193431;NM_012411;NM_015967;XM_005270738 ENSP00000352833 Q9Y2R2 TRUE can 0 0 0 Last Universal Common Ancestor 2 Cellular metabolism,Cellular processes,Signal transduction chr1 114357530 114414245 |LYP1|LYP2|PTPN8| NP_057051 0 FALSE 1 15 603 0.3710
26245 OR2M4 olfactory receptor, family 2, subfamily M, member 4 1q44 14946 8270 - NP_059974 NM_017504 ENSP00000306688 Q96R27 TRUE can 0 0 5 Mammals 0 Cell response to stimuli,Signal transduction chr1 248402231 248403163 |HSHTPCRX18|HTPCRX18|OR1-55|OST710|TPCR100| NP_059974 5 TRUE 1 1
26338 OR5L2 olfactory receptor, family 5, subfamily L, member 2 11q11 15046 8351 - NP_001004739 NM_001004739 ENSP00000367650 Q8NGL0 TRUE can 0 0 1 Mammals 0 Cell response to stimuli,Signal transduction chr11 55594695 55595627 |HSHTPCRX16|HTPCRX16|OR11-153| NP_001004739 1 TRUE 1 1
26503 SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5 6q13 5058 10933 604322 NP_036566;XP_005248767;XP_005248768;XP_006715522 NM_012434;XM_005248710;XM_005248711;XM_006715459 ENSP00000348019 Q9NRA2 TRUE can 0 0 0 Last Universal Common Ancestor 7 Cellular processes chr6 74304803 74363609 |AST|ISSD|NSD|SIALIN|SIASD|SLD| NP_036566 0 FALSE 1 1 0 0.0000
26511 CHIC2 cysteine-rich hydrophobic domain 2 4q11 10373 1935 604332 NP_036242;XP_005265795;XP_006714100 NM_012110;XM_005265738;XM_006714037 ENSP00000263921 Q9UKJ5 TRUE cgc 1 0 0 - 4 -1 chr4 54876265 54930467 |BTL| NP_036242 0 FALSE 1 20 8094 0.0950
26953 RANBP6 RAN binding protein 6 9p24.1 17953 9851 - NP_001230131;NP_001230132;NP_036548 NM_001243202;NM_001243203;NM_012416 ENSP00000259569 O60518 TRUE can 0 0 1 Eukaryotes 2 Cellular processes chr9 6012293 6015607 |NA| NP_036548 1 FALSE 1 11 909 0.1270
26986 PABPC1 poly(A) binding protein, cytoplasmic 1 8q22.2-q23 5247 8554 604679 NP_002559;XP_005250918 NM_002568;XM_005250861 ENSP00000313007 P11940 TRUE can 0 0 4 Eukaryotes 3 DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr8 101716529 101733811 |PABP|PABPC2| NP_002559 4 FALSE 1 171 111166 0.1260 22
27004 TCL6 T-cell leukemia/lymphoma 6 (non-protein coding) 14q32.1 - 13463 604412 - NM_012468;NM_014418;NM_020550;NM_020552;NM_020553;NM_020554;NR_028288 - NA TRUE cgc 1 0 -1 - 0 -1 - 0 0 |TNG1|TNG2| - -1 FALSE 1
27086 FOXP1 forkhead box P1 3p14.1 18518 3823 605515 NP_001012523;NP_001231737;NP_001231739;NP_001231741;NP_001231742;NP_001231743;NP_001231744;NP_001231745;NP_116071;XP_005264786;XP_005264792;XP_005264793;XP_005264794;XP_005264795;XP_005264799;XP_006713165;XP_006713166;XP_006713167;XP_006713168;XP_006713169;XP_006713170 NM_001012505;NM_001244808;NM_001244810;NM_001244812;NM_001244813;NM_001244814;NM_001244815;NM_001244816;NM_032682;XM_005264729;XM_005264735;XM_005264736;XM_005264737;XM_005264738;XM_005264742;XM_006713102;XM_006713103;XM_006713104;XM_006713105;XM_006713106;XM_006713107;XR_427266 ENSP00000318902 Q9H334 TRUE cgc 1 0 0 Metazoans 7 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr3 71008401 71247532 |12CC4|QRF1|hFKH1B| NP_001231739 0 FALSE 1 10 2415 0.1780
27125 AFF4 AF4/FMR2 family, member 4 5q31 9187 17869 604417 NP_055238;XP_005272020;XP_005272021;XP_006714650 NM_014423;XM_005271963;XM_005271964;XM_006714587 ENSP00000265343 Q9UHB7 TRUE cgc 1 0 0 Metazoans 8 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr5 132216754 132272881 |AF5Q31|MCEF| NP_055238 0 FALSE 1 22 3583 0.2210
27127 SMC1B structural maintenance of chromosomes 1B 22q13.31 10564 11112 608685 NP_683515;XP_005261623 NM_148674;XM_005261566;XR_244368 ENSP00000350036 Q8NDV3 TRUE can 0 0 0 Last Universal Common Ancestor 0 Cell cycle,DNA/RNA metabolism and transcription chr22 45740440 45809448 |SMC1BETA|SMC1L2| NP_683515 0 FALSE 1 1 0 0.0000 7
27154 BRPF3 bromodomain and PHD finger containing, 3 6p21 16565 14256 - NP_056510;XP_005249067;XP_005249068;XP_006715122;XP_006715123 NM_015695;XM_005249010;XM_005249011;XM_006715059;XM_006715060;XR_241886;XR_241887 ENSP00000350267 Q9ULD4 TRUE can 0 0 0 Eukaryotes 3 -1 chr6 36168100 36198383 |NA| NP_056510 0 FALSE 1 7 599 0.5240 1
27164 SALL3 spalt-like transcription factor 3 18q23 5467 10527 605079 NP_741996 NM_171999 ENSP00000441823;ENSP00000461114 Q9BXA9 TRUE can 0 0 0 Metazoans 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr18 76740275 76757319 |ZNF796| NP_741996 0 FALSE 1 3 6 0.3330
27181 SIGLEC8 sialic acid binding Ig-like lectin 8 19q13.33-q13.41 16132 10877 605639 NP_055257 NM_014442;XR_243922 ENSP00000321077 Q9NYZ4 TRUE can 0 0 1 Vertebrates 1 Signal transduction chr19 51955636 51961641 |SAF2|SIGLEC-8|SIGLEC8L| NP_055257 1 FALSE 1 1 0 0.0000
27231 NMRK2 nicotinamide riboside kinase 2 19p13.3 16371 17871 608705 NP_001276046;NP_733778;XP_006722788;XP_006722789 NM_001289117;NM_014446;NM_170678;NR_110316;XM_006722725;XM_006722726 ENSP00000168977 Q9NPI5 TRUE can 0 0 0 Last Universal Common Ancestor 3 Cellular metabolism,DNA/RNA metabolism and transcription chr19 3936574 3942268 |ITGB1BP3|MIBP| NP_001276046 0 FALSE 1 7 2719 0.0480 2
27253 PCDH17 protocadherin 17 13q21.1 - 14267 611760 NP_001035519;XP_005266414;XP_005266415 NM_001040429;NM_014459;XM_005266357;XM_005266358 ENSP00000367151 O14917 TRUE can 0 0 0 Eukaryotes 0 Cell motility and interactions chr13 58206681 58299425 |PCDH68|PCH68| NP_001035519 0 FALSE 1 5 819 0.0000
27284 SULT1B1 sulfotransferase family, cytosolic, 1B, member 1 4q13.3 - 17845 608436 NP_055280;XP_005265733;XP_005265734;XP_005265735 NM_014465;XM_005265676;XM_005265677;XM_005265678 ENSP00000308770 O43704 TRUE can 0 0 0 Eukaryotes 4 Cellular metabolism chr4 70592809 70620917 |ST1B1|ST1B2|SULT1B2| XP_005265733 0 FALSE 1 4 1009 0.0000
27315 PGAP2 post-GPI attachment to proteins 2 11p15.5 17016 17893 615187 NP_001138910;NP_001243164;NP_001243165;NP_001243166;NP_001243167;NP_001243168;NP_001243169;NP_001269967;NP_001269968;NP_001269969;NP_055304;XP_006718244;XP_006718245;XP_006718246;XP_006718247;XP_006718248;XP_006718249;XP_006718250;XP_006718251;XP_006718252;XP_006718253;XP_006718254;XP_006718255;XP_006718256 NM_001145438;NM_001256235;NM_001256236;NM_001256237;NM_001256238;NM_001256239;NM_001256240;NM_001283038;NM_001283039;NM_001283040;NM_014489;NR_027016;NR_027017;NR_027018;NR_045923;NR_045925;NR_045926;NR_045927;NR_045929;NR_104270;NR_104271;NR_104272;XM_006718181;XM_006718182;XM_006718183;XM_006718184;XM_006718185;XM_006718186;XM_006718187;XM_006718188;XM_006718189;XM_006718190;XM_006718191;XM_006718192;XM_006718193 ENSP00000278243 Q9UHJ9 TRUE can 0 0 0 Eukaryotes 0 Cellular metabolism,Cellular processes chr11 3819074 3846685 |CWH43-N|HPMRS3| NP_001243165 0 FALSE 1 1 0 0.0000
27316 RBMX RNA binding motif protein, X-linked Xq26.3 2186 9910 300199 NP_001158275;NP_002130 NM_001164803;NM_002139;NR_028476;NR_028477 ENSP00000359645 P38159 TRUE can 0 0 6 Eukaryotes 0 DNA/RNA metabolism and transcription,Regulation of transcription chrX 135956304 135961586 |HNRNPG|RBMXRT|RNMX|hnRNP-G| NP_002130 6 FALSE 1 101 34013 0.1780 12
27328 PCDH11X protocadherin 11 X-linked Xq21.3 2215 8656 300246 NP_001161832;NP_001161833;NP_001161834;NP_001161835;NP_055337;NP_116749;NP_116750;NP_116751 NM_001168360;NM_001168361;NM_001168362;NM_001168363;NM_014522;NM_032967;NM_032968;NM_032969 ENSP00000362186 Q9BZA7 TRUE can 0 0 1 Metazoans 0 Cell motility and interactions chrX 91090504 91873936 |PCDH-X|PCDH11|PPP1R119| NP_116750 1 FALSE 2 1 0 0.0000
27332 ZNF638 zinc finger protein 638 2p13.1 11736 17894 614349 NP_001014972;NP_001239541;NP_001239542;NP_055312;XP_005264318;XP_005264319;XP_005264320;XP_005264321;XP_006712052;XP_006712053 NM_001014972;NM_001252612;NM_001252613;NM_014497;XM_005264261;XM_005264262;XM_005264263;XM_005264264;XM_006711989;XM_006711990;XR_244928 ENSP00000264447 Q14966 TRUE can 0 0 0 Vertebrates 3 DNA/RNA metabolism and transcription,Regulation of transcription chr2 71503769 71661934 |NP220|ZFML|Zfp638| XP_005264318 0 FALSE 1 34 9306 0.0820
27340 UTP20 UTP20, small subunit (SSU) processome component, homolog (yeast) 12q23 9928 17897 612822 NP_055318;XP_006719406 NM_014503;XM_006719343 ENSP00000261637 O75691 TRUE can 0 0 0 Eukaryotes 3 Cell cycle,Regulation of intracellular processes and metabolism chr12 101674061 101779898 |DRIM| NP_055318 0 FALSE 1 13 867 0.1150
27436 EML4 echinoderm microtubule associated protein like 4 2p21 6310 1316 607442 NP_001138548;NP_061936;XP_005264324;XP_005264325;XP_006712054;XP_006712055 NM_001145076;NM_019063;XM_005264267;XM_005264268;XM_006711991;XM_006711992 ENSP00000320663 Q9HC35 TRUE cgc 1 0 0 Last Universal Common Ancestor 5 Cell cycle,Cellular processes chr2 42472644 42557344 |C2orf2|ELP120|EMAP-4|EMAPL4|ROPP120| XP_005264324 0 FALSE 1 5 588 0.0000
27445 PCLO piccolo presynaptic cytomatrix protein 7q11.23-q21.3 16078 13406 604918 NP_055325;NP_149015;XP_006715989 NM_014510;NM_033026;XM_006715926 ENSP00000334319 Q9Y6V0 TRUE can 0 0 0 Metazoans 0 Cellular processes,Multicellular activities,Signal transduction chr7 82387894 82791908 |ACZ| NP_149015 0 TRUE 1 4 45 0.3330
28513 CDH19 cadherin 19, type 2 18q22.1 4311 1758 603016 NP_001257957;NP_066976;XP_006722503;XP_006722504 NM_001271028;NM_021153;NR_073130;XM_006722440;XM_006722441 ENSP00000262150;ENSP00000319166 Q9H159 TRUE can 0 0 0 Last Universal Common Ancestor 1 Cell motility and interactions chr18 64172052 64239441 |CDH7L2| NP_066976 0 FALSE 1 1 0 0.0000
29072 SETD2 SET domain containing 2 3p21.31 11043 18420 612778 NP_054878;XP_005265151;XP_006713182;XP_006713183 NM_012271;NM_014159;XM_005265094;XM_006713119;XM_006713120 ENSP00000386759 Q9BYW2 TRUE cgc 0 1 0 Last Universal Common Ancestor 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr3 47058586 47205414 |HBP231|HIF-1|HIP-1|HYPB|KMT3A|SET2|p231HBP| NP_054878 0 FALSE 6 15 2548 0.0950
29086 BABAM1 BRISC and BRCA1 A complex member 1 19p13.11 13702 25008 612766 NP_001028721;NP_001275685;NP_001275686;NP_054892 NM_001033549;NM_001288756;NM_001288757;NM_014173 ENSP00000352408 Q9NWV8 TRUE can 0 0 0 Metazoans 4 -1 chr19 17379616 17389854 |C19orf62|MERIT40|NBA1| NP_001028721 0 FALSE 1 55 19208 0.0590
29117 BRD7 bromodomain containing 7 16q12 - 14310 - NP_001167455;NP_037395;XP_005255968;XP_005255969 NM_001173984;NM_013263;XM_005255911;XM_005255912 ENSP00000378181 Q9NPI1 TRUE can 0 0 3 Eukaryotes 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction chr16 50353125 50402685 |CELTIX1|NAG4| NP_001167455 3 FALSE 1 47 5092 0.0990
29119 CTNNA3 catenin (cadherin-associated protein), alpha 3 10q22.2 9639 2511 607667 NP_001120856;NP_037398;XP_005269774;XP_006717868;XP_006717869;XP_006717870 NM_001127384;NM_013266;XM_005269717;XM_006717805;XM_006717806;XM_006717807 ENSP00000362849 Q9UI47 TRUE can 0 0 0 Metazoans 0 -1 chr10 67680091 69407277 |ARVD13|VR22| XP_005269774 0 TRUE 1 6 110 0.2000
29126 CD274 CD274 molecule 9p24 5655 17635 605402 NP_001254635;NP_054862;XP_006716822 NM_001267706;NM_014143;NR_052005;XM_006716759 ENSP00000370989 Q9NZQ7 TRUE cgc 1 0 0 Vertebrates 6 Cell cycle,Immune system response,Regulation of intracellular processes and metabolism,Signal transduction chr9 5456114 5466828 |B7-H|B7H1|PD-L1|PDCD1L1|PDCD1LG1|PDL1| NP_054862 0 FALSE 1 3 460 0.0000 3
29761 USP25 ubiquitin specific peptidase 25 21q11.2 5296 12624 604736 NP_001269970;NP_001269971;NP_037528;XP_005261006;XP_006724055 NM_001283041;NM_001283042;NM_013396;XM_005260949;XM_006723992;XR_430349 ENSP00000285679 Q9UHP3 TRUE can 0 0 0 Eukaryotes 5 Cellular metabolism,Cellular processes chr21 17102713 17250791 |NA| NP_001269970 0 FALSE 1 38 7518 0.0800
29775 CARD10 caspase recruitment domain family, member 10 22q13.1 6233 16422 607209 NP_055365 NM_014550 ENSP00000251973 Q9BWT7 TRUE can 0 0 0 Vertebrates 6 Cell cycle,Regulation of intracellular processes and metabolism,Signal transduction chr22 37887200 37915207 |BIMP1|CARMA3| NP_055365 0 FALSE 1 4 50 0.1670
29844 TFPT TCF3 (E2A) fusion partner (in childhood Leukemia) 19q13 10266 13630 609519 NP_037474;XP_005258882;XP_005277131;XP_005277309;XP_005278318;XP_006725832;XP_006725933;XP_006726021;XP_006726120;XP_006726218;XP_006726258 NM_013342;XM_005258825;XM_005277074;XM_005277252;XM_005278261;XM_006725769;XM_006725870;XM_006725958;XM_006726057;XM_006726155;XM_006726195 ENSP00000375639;ENSP00000458632;ENSP00000470149;ENSP00000470971;ENSP00000471904;ENSP00000472186;ENSP00000472539;ENSP00000472608;ENSP00000473133 P0C1Z6 TRUE cgc 1 0 0 Metazoans 1 -1 chr19 54610360 54618079 |FB1|INO80F|amida| NP_037474 0 FALSE 1 38 9303 0.1520 3
29940 DSE dermatan sulfate epimerase 6q22 5807 21144 605942 NP_001074445;NP_037484;XP_005267010 NM_001080976;NM_013352;XM_005266953 ENSP00000332151 Q9UL01 TRUE can 0 0 1 Metazoans 1 Cellular metabolism chr6 116720414 116758505 |DSEPI|EDSMC2|SART-2|SART2| NP_001074445 1 FALSE 1 2 2 0.0000
29994 BAZ2B bromodomain adjacent to zinc finger domain, 2B 2q24.2 9295 963 605683 NP_038478;XP_005246545;XP_005246546;XP_005246549;XP_005246554;XP_005246557;XP_006712524;XP_006712525;XP_006712526;XP_006712527;XP_006712528;XP_006712529;XP_006712530;XP_006712531;XP_006712532;XP_006712533;XP_006712534;XP_006712535;XP_006712536;XP_006712537 NM_013450;XM_005246488;XM_005246489;XM_005246492;XM_005246497;XM_005246500;XM_006712461;XM_006712462;XM_006712463;XM_006712464;XM_006712465;XM_006712466;XM_006712467;XM_006712468;XM_006712469;XM_006712470;XM_006712471;XM_006712472;XM_006712473;XM_006712474 ENSP00000376534 Q9UIF8 TRUE can 0 0 0 Eukaryotes 1 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr2 160176779 160335230 |WALp4| XP_005246545 0 FALSE 1 10 2410 0.0890
29998 GLTSCR1 glioma tumor suppressor candidate region gene 1 19q13.3 9296 4332 605690 NP_056526;XP_005258890;XP_006723243 NM_015711;XM_005258833;XM_006723180 ENSP00000379946 Q9NZM4 TRUE can 0 0 0 Metazoans 0 -1 chr19 48176832 48205669 |NA| NP_056526 0 FALSE 1 8 177 0.6070
30012 TLX3 T-cell leukemia homeobox 3 5q35.1 6868 13532 604640 NP_066305 NM_021025 ENSP00000296921 O43711 TRUE cgc 1 0 0 Metazoans 2 Cell cycle,Cell motility and interactions,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription chr5 170736370 170738600 |HOX11L2|RNX| NP_066305 0 FALSE 1 16 2396 0.0330
30849 PIK3R4 phosphoinositide-3-kinase, regulatory subunit 4 3q22.1 4010 8982 602610 NP_055417 NM_014602 ENSP00000349205 Q99570 TRUE can 0 0 0 Eukaryotes 1 Cellular metabolism,Cellular processes chr3 130398162 130464062 |VPS15| NP_055417 0 FALSE 1 13 1896 0.2180 8
50615 IL21R interleukin 21 receptor 16p11 5649 6006 605383 NP_068570;NP_851564;NP_851565 NM_021798;NM_181078;NM_181079 ENSP00000338010 Q9HBE5 TRUE cgc 1 0 0 Vertebrates 5 Immune system response chr16 27414492 27460601 |CD360|NILR| NP_851565 0 FALSE 1 4 148 0.0000
50802 IGK immunoglobulin kappa locus 2p12 - - - - - - NA TRUE cgc 1 0 -1 - 0 -1 - 0 0 |IGK@| - -1 FALSE 1
50853 VILL villin-like 3p21.3 18283 30906 - NP_056957;XP_005265248;XP_005265249;XP_006713246;XP_006713247;XP_006713248 NM_015873;XM_005265191;XM_005265192;XM_006713183;XM_006713184;XM_006713185;XR_245137 ENSP00000283713 O15195 TRUE can 0 0 0 Eukaryotes 1 Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism chr3 38035164 38048543 |NA| NP_056957 0 FALSE 1 1 0 0.0000
50939 IMPG2 interphotoreceptor matrix proteoglycan 2 3q12.2-q12.3 6135 18362 607056 NP_057331 NM_016247 ENSP00000193391 Q9BZV3 TRUE can 0 0 0 Vertebrates 0 -1 chr3 100947640 101039216 |IPM200|RP56|SPACRCAN| NP_057331 0 FALSE 1
50944 SHANK1 SH3 and multiple ankyrin repeat domains 1 19q13.3 5413 15474 604999 NP_057232;XP_005259020;XP_006723296;XP_006723297 NM_016148;XM_005258963;XM_006723233;XM_006723234 ENSP00000293441 Q9Y566 TRUE can 0 0 0 Last Universal Common Ancestor 1 Cellular processes chr19 51165225 51220176 |SPANK-1|SSTRIP|synamon| XP_005259020 0 FALSE 1 19 1973 0.0640
50945 TBX22 T-box 22 Xq21.1 2253 11600 300307 NP_001103348;NP_001103349;NP_058650;XP_005262193;XP_005262194;XP_005262195;XP_006724720;XP_006725480;XP_006725481;XP_006725482;XP_006725483 NM_001109878;NM_001109879;NM_016954;XM_005262136;XM_005262137;XM_005262138;XM_006724657;XM_006725417;XM_006725418;XM_006725419;XM_006725420;XR_430822 ENSP00000362390 Q9Y458 TRUE can 0 0 0 Vertebrates 4 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chrX 79277769 79286607 |ABERS|CLPA|TBXX|dJ795G23.1| XP_005262193 0 FALSE 1 5 1580 0.5000
51059 FAM135B family with sequence similarity 135, member B 8q24.23 14230 28029 - NP_056996;XP_005250985;XP_006716634 NM_015912;XM_005250928;XM_006716571 ENSP00000378710 Q49AJ0 TRUE can 0 0 0 Eukaryotes 0 -1 chr8 139144839 139380226 |C8ORFK32| NP_056996 0 FALSE 2 2 56 0.0000
51119 SBDS Shwachman-Bodian-Diamond syndrome 7q11.21 7393 19440 607444 NP_057122 NM_016038 ENSP00000246868;ENSP00000257549 Q9Y3A5 TRUE cgc 0 1 1 Last Universal Common Ancestor 1 Cell cycle,Cell motility and interactions,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Immune system response,Multicellular activities,Regulation of intracellular processes and metabolism,Regulation of transcription chr7 66453361 66460404 |SWDS| NP_057122 1 FALSE 1 35 4297 0.1340
51134 CEP83 centrosomal protein 83kDa 12q22 14869 17966 615847 NP_001035858;NP_057206;XP_005268999;XP_006719500 NM_001042399;NM_016122;XM_005268942;XM_006719437;XR_429106 ENSP00000344655 Q9Y592 TRUE can 0 0 0 Metazoans 5 -1 chr12 94702592 94806266 |CCDC41|NPHP18|NY-REN-58| NP_001035858 0 FALSE 1 1 0 0.0000 5
51135 IRAK4 interleukin-1 receptor-associated kinase 4 12q12 - 17967 606883 NP_001107654;NP_001138728;NP_001138729;NP_001138730;NP_057207;XP_005269000;XP_005269001;XP_005269002;XP_005269003;XP_005269004;XP_005269005;XP_005269006;XP_006719501;XP_006719502;XP_006719503;XP_006719504;XP_006719505;XP_006719506 NM_001114182;NM_001145256;NM_001145257;NM_001145258;NM_016123;XM_005268943;XM_005268944;XM_005268945;XM_005268946;XM_005268947;XM_005268948;XM_005268949;XM_006719438;XM_006719439;XM_006719440;XM_006719441;XM_006719442;XM_006719443 ENSP00000390651 Q9NWZ3 TRUE can 0 0 0 Last Universal Common Ancestor 2 Cellular metabolism,Cellular processes,Signal transduction chr12 44161915 44180363 |IPD1|IRAK-4|NY-REN-64|REN64| NP_001107654 0 FALSE 1 25 1160 0.1670 34
51163 DBR1 debranching RNA lariats 1 3q22.3 7384 15594 607024 NP_057300 NM_016216 ENSP00000260803 Q9UK59 TRUE can 0 0 0 Last Universal Common Ancestor 0 DNA/RNA metabolism and transcription,Regulation of transcription chr3 137880734 137893637 |NA| NP_057300 0 FALSE 1 3 65 0.0000
51199 NIN ninein (GSK3B interacting protein) 14q22.1 9785 14906 608684 NP_057434;NP_065972;NP_891989;NP_891991;XP_005267792;XP_005267793;XP_005267794;XP_006720223;XP_006720224 NM_016350;NM_020921;NM_182944;NM_182945;NM_182946;XM_005267735;XM_005267736;XM_005267737;XM_006720160;XM_006720161 ENSP00000371472 Q8N4C6 TRUE cgc 1 0 0 Metazoans 14 Cellular metabolism,Cellular processes,Signal transduction chr14 51190184 51288774 |SCKL7| NP_065972 0 FALSE 1 12 1007 0.1820
51225 ABI3 ABI family, member 3 17q21.3 5900 29859 606363 NP_001128658;NP_057512;XP_005257486 NM_001135186;NM_016428;XM_005257429 ENSP00000225941 Q9P2A4 TRUE can 0 0 0 Eukaryotes 0 Cell motility and interactions,Cellular metabolism,Cellular processes chr17 47288087 47300074 |NESH|SSH3BP3| XP_005257486 0 FALSE 1 35 6335 0.0550
51259 TMEM216 transmembrane protein 216 11q13.1 - 25018 613277 NP_001167461;NP_001167462;NP_057583;XP_005274096 NM_001173990;NM_001173991;NM_016499;XM_005274039 ENSP00000440638 Q9P0N5 TRUE can 0 0 0 Metazoans 0 -1 chr11 61160702 61165445 |NA| NP_001167462 0 FALSE 1 2 153 0.0000 2
51289 RXFP3 relaxin/insulin-like family peptide receptor 3 5p15.1-p14 - 24883 609445 NP_057652 NM_016568 ENSP00000328708 Q9NSD7 TRUE can 0 0 0 Metazoans 2 Regulation of intracellular processes and metabolism,Signal transduction chr5 33936846 33938252 |GPCR135|RLN3R1|RXFPR3|SALPR| NP_057652 0 FALSE 1 2 16251 0.0000 3
51322 WAC WW domain containing adaptor with coiled-coil 10p12.1|10p12.1-p11.2 18291 17327 615049 NP_057712;NP_567823;XP_005252511;XP_005252514;XP_005252516 NM_016628;NM_100264;NM_100486;NR_024557;XM_005252454;XM_005252457;XM_005252459 ENSP00000346986 Q9BTA9 TRUE can 0 0 0 Eukaryotes 0 -1 chr10 28822509 28908532 |BM-016|PRO1741|Wwp4| XP_005252511 0 FALSE 1 24 11885 0.0540
51364 ZMYND10 zinc finger, MYND-type containing 10 3p21.3 6145 19412 607070 NP_056980;XP_005265273 NM_015896;XM_005265216 ENSP00000231749 O75800 TRUE can 0 0 0 Eukaryotes 0 -1 chr3 50378844 50383010 |BLU|CILD22|FLU| NP_056980 0 FALSE 1 7 14899 0.0000
51366 UBR5 ubiquitin protein ligase E3 component n-recognin 5 8q22 6436 16806 608413 NP_001269802;NP_056986;XP_005251013;XP_005251014;XP_005251016;XP_005251017;XP_005251019 NM_001282873;NM_015902;XM_005250956;XM_005250957;XM_005250959;XM_005250960;XM_005250962;XR_242392 ENSP00000429084 O95071 TRUE cgc 0 0 0 Metazoans 5 Cellular metabolism,Cellular processes,Signal transduction chr8 103266533 103424462 |DD5|EDD|EDD1|HYD| XP_005251013 0 FALSE 1 83 22911 0.0820 2
51375 SNX7 sorting nexin 7 1p21.3 15416 14971 614904 NP_057060;NP_689424;XP_006710740;XP_006710741;XP_006710742 NM_015976;NM_152238;NR_033716;XM_006710677;XM_006710678;XM_006710679 ENSP00000304429 Q9UNH6 TRUE can 0 0 1 Eukaryotes 7 Cellular processes chr1 99127288 99225684 |NA| NP_057060 1 FALSE 1 14 1987 0.0880
51428 DDX41 DEAD (Asp-Glu-Ala-Asp) box polypeptide 41 5q35.3 10490 18674 608170 NP_057306;XP_006714933 NM_016222;XM_006714870 ENSP00000422753 Q9UJV9 TRUE can 0 0 0 Eukaryotes 3 Cell cycle,DNA/RNA metabolism and transcription,Regulation of transcription chr5 176938795 176943836 |ABS| NP_057306 0 FALSE 1 17 3639 0.1470 3
51438 MAGEC2 melanoma antigen family C, 2 Xq27 6632 13574 300468 NP_057333 NM_016249 ENSP00000354660 Q9UBF1 TRUE can 0 0 1 Eukaryotes 0 -1 chrX 141290655 141291773 |CT10|HCA587| NP_057333 1 FALSE 1 13 3469 0.0640
51501 C11orf73 chromosome 11 open reading frame 73 11q14.2 13701 26938 614908 NP_057485;XP_006718645;XP_006718646;XP_006718647 NM_016401;NR_024596;NR_024597;NR_024598;XM_006718582;XM_006718583;XM_006718584 ENSP00000278483 Q53FT3 TRUE can 0 0 2 Eukaryotes 0 -1 chr11 86017287 86056677 |HSPC179|Hikeshi|L7RN6|OPI10| NP_057485 2 FALSE 1 2 95 0.0000 2
51517 NCKIPSD NCK interacting protein with SH3 domain 3p21 9450 15486 606671 NP_057537;NP_909119;XP_005265280;XP_006713268 NM_016453;NM_184231;XM_005265223;XM_006713205 ENSP00000294129;ENSP00000314655;ENSP00000354313;ENSP00000465676 Q9NZQ3 TRUE cgc 1 0 0 Metazoans 1 Cellular processes,Signal transduction chr3 48711980 48723240 |AF3P21|SPIN90|VIP54|WASLBP|WISH| NP_057537 0 FALSE 1 26 4007 0.1850 5
51592 TRIM33 tripartite motif containing 33 1p13.1 10423 16290 605769 NP_056990;NP_148980;XP_005270993;XP_005270994 NM_015906;NM_033020;XM_005270936;XM_005270937 ENSP00000351250 Q9UPN9 TRUE cgc 1 0 0 Eukaryotes 3 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr1 114940273 115053697 |ECTO|PTC7|RFG7|TF1G|TIF1G|TIF1GAMMA|TIFGAMMA| XP_005270993 0 FALSE 1 46 13201 0.1510 7
51684 SUFU suppressor of fused homolog (Drosophila) 10q24.32 6124 16466 607035 NP_001171604;NP_057253;XP_006717955 NM_001178133;NM_016169;XM_006717892 ENSP00000358918 Q9UMX1 TRUE cgc 0 1 0 Last Universal Common Ancestor 1 Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction chr10 104263910 104389909 |PRO1280|SUFUH|SUFUXL| NP_057253 0 FALSE 1 27 5045 0.0200 15
51755 CDK12 cyclin-dependent kinase 12 17q12 10849 24224 615514 NP_055898;NP_057591;XP_005257513;XP_005257515 NM_015083;NM_016507;XM_005257456;XM_005257458;XR_429896;XR_429897;XR_429898;XR_429899;XR_429900;XR_429901;XR_429902;XR_429903;XR_429904 ENSP00000398880 Q9NYV4 TRUE cgc 0 1 0 Eukaryotes 0 Cellular metabolism,Cellular processes chr17 37618325 37687566 |CRK7|CRKR|CRKRS| NP_057591 0 FALSE 2 27 24409 0.1340 1
53335 BCL11A B-cell CLL/lymphoma 11A (zinc finger protein) 2p16.1 5949 13221 606557 NP_060484;NP_075044;NP_612569 NM_018014;NM_022893;NM_138553;NM_138559 ENSP00000338774 Q9H165 TRUE cgc 1 0 0 Eukaryotes 6 Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription chr2 60687542 60780405 |BCL11A-L|BCL11A-S|BCL11A-XL|BCL11a-M|CTIP1|EVI9|HBFQTL5|ZNF856| NP_075044 0 FALSE 1 25 8482 0.1230
53353 LRP1B low density lipoprotein receptor-related protein 1B 2q21.2 16383 6693 608766 NP_061027 NM_018557 ENSP00000374135 Q9NZR2 TRUE can 0 0 0 Metazoans 2 Cellular processes chr2 140990758 142888298 |LRP-DIT|LRPDIT| NP_061027 0 TRUE 6 8 992 0.1790
53942 CNTN5 contactin 5 11q22.1 6241 2175 607219 NP_001230199;NP_001230200;NP_055176;NP_780775 NM_001243270;NM_001243271;NM_014361;NM_175566 ENSP00000279463 O94779 TRUE can 0 0 0 Metazoans 0 -1 chr11 99426946 100226948 |HNB-2s|NB-2| NP_001230199 0 TRUE 1 1 0 0.0000
54084 TSPEAR thrombospondin-type laminin G domain and EAR repeats 21q22.3 9845 1268 612920 NP_001258966;NP_659428;XP_005261214 NM_001272037;NM_144991;XM_005261157 ENSP00000321987 Q8WU66 TRUE can 0 0 0 Eukaryotes 0 -1 chr21 45919669 46131429 |C21orf29|DFNB98|TSP-EAR| NP_659428 0 FALSE 1
54206 ERRFI1 ERBB receptor feedback inhibitor 1 1p36 9218 18185 608069 NP_061821;XP_005263534;XP_006710760 NM_018948;XM_005263477;XM_006710697 ENSP00000366702 Q9UJM3 TRUE can 0 0 0 Vertebrates 1 -1 chr1 8073273 8075679 |GENE-33|MIG-6|RALT| NP_061821 0 FALSE 1 21 4276 0.1000
54437 SEMA5B sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B 3q21.1 15322 10737 609298 NP_001026872;NP_001243275;NP_001243276;NP_001243277 NM_001031702;NM_001256346;NM_001256347;NM_001256348;NM_018987;NR_046079 ENSP00000350215 Q9P283 TRUE can 0 0 0 Opisthokonts 0 Development chr3 122628993 122694970 |SEMAG|SemG| NP_001243276 0 FALSE 1 8 141 0.0000
54439 RBM27 RNA binding motif protein 27 5q32 - 29243 - NP_061862;XP_005268523;XP_005268524;XP_005268525;XP_006714850 NM_018989;XM_005268466;XM_005268467;XM_005268468;XM_006714787;XR_245858 ENSP00000265271;ENSP00000301011 Q9P2N5 TRUE can 0 0 0 Eukaryotes 0 -1 chr5 145583329 145665590 |ARRS1|Psc1| XP_005268523 0 FALSE 1 14 443 0.2640
54510 PCDH18 protocadherin 18 4q31 12205 14268 608287 NP_061908;XP_005263127;XP_006714302 NM_019035;XM_005263070;XM_006714239 ENSP00000355082 Q9HCL0 TRUE can 0 0 0 Eukaryotes 0 Cell motility and interactions,Development chr4 138442186 138453242 |PCDH68L| NP_061908 0 FALSE 1 1 0 0.0000
54674 LRRN3 leucine rich repeat neuronal 3 7q31.1 14321 17200 - NP_001093128;NP_001093130;NP_060804 NM_001099658;NM_001099660;NM_018334 ENSP00000312001 Q9H3W5 TRUE can 0 0 0 Eukaryotes 2 -1 chr7 110762829 110764952 |FIGLER5|NLRR-3|NLRR3| NP_001093128 0 FALSE 1
54738 FEV FEV (ETS oncogene family) 2q36 6193 18562 607150 NP_059991 NM_017521 ENSP00000295727 Q99581 TRUE cgc 1 0 0 Vertebrates 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr2 219846392 219849797 |HSRNAFEV|PET-1| NP_059991 0 FALSE 1
54758 KLHDC4 kelch domain containing 4 16q24 11180 25272 - NP_001171783;NP_001171785;NP_060036;XP_005256051;XP_005256055;XP_005256056;XP_005256058;XP_006721264;XP_006721265;XP_006721266;XP_006721267;XP_006721268 NM_001184854;NM_001184856;NM_017566;XM_005255994;XM_005255998;XM_005255999;XM_005256001;XM_006721201;XM_006721202;XM_006721203;XM_006721204;XM_006721205;XR_429719;XR_429720 ENSP00000270583 Q8TBB5 TRUE can 0 0 0 Eukaryotes 2 -1 chr16 87741960 87799496 |NA| NP_060036 0 FALSE 1 8 1015 0.0710
54768 HYDIN HYDIN, axonemal central pair apparatus protein 16q22.2 11042 19368 610812 NP_001185471;NP_001185472;NP_001257903;NP_060028;XP_006721269 NM_001198542;NM_001198543;NM_001270974;NM_017558;NM_032821;XM_006721206 ENSP00000314736 Q4G0P3 TRUE can 0 0 0 Opisthokonts 0 -1 chr16 70841486 71220798 |CILD5|HYDIN1|PPP1R31| NP_001257903 0 FALSE 1 2 73 0.0000
54790 TET2 tet methylcytosine dioxygenase 2 4q24 7876 25941 612839 NP_001120680;NP_060098;XP_005263139;XP_006714305;XP_006714306 NM_001127208;NM_017628;XM_005263082;XM_006714242;XM_006714243;XR_244633;XR_244634;XR_427546;XR_427547 ENSP00000369351 Q6N021 TRUE cgc 0 1 0 Metazoans 1 -1 chr4 106155100 106197673 |KIAA1546| NP_001120680 0 FALSE 2 5 51 0.1000
54796 BNC2 basonuclin 2 9p22.2 12274 30988 608669 NP_060107;XP_006716847;XP_006716848;XP_006716849;XP_006716850;XP_006716851;XP_006716852;XP_006716853 NM_017637;XM_006716784;XM_006716785;XM_006716786;XM_006716787;XM_006716788;XM_006716789;XM_006716790 ENSP00000370047 Q6ZN30 TRUE can 0 0 0 Metazoans 1 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr9 16418990 16738483 |BSN2| NP_060107 0 FALSE 1 2 179 0.0000
54825 CDHR2 cadherin-related family member 2 5q35.2 15103 18231 - NP_001165447;NP_060145;XP_006714950 NM_001171976;NM_017675;XM_006714887 ENSP00000261944 Q9BYE9 TRUE can 0 0 0 Eukaryotes 1 Cell cycle,Cell motility and interactions,Regulation of intracellular processes and metabolism chr5 175992354 176022670 |PCDH24|PCLKC| NP_001165447 0 FALSE 1 4 3023 0.5000
54855 FAM46C family with sequence similarity 46, member C 1p12 13312 24712 613952 NP_060179 NM_017709 ENSP00000358458 Q5VWP2 TRUE cgc 0 1 1 Metazoans 2 -1 chr1 118165491 118166663 |NA| NP_060179 1 FALSE 1 8 973 0.1790
54880 BCOR BCL6 corepressor Xp11.4 6458 20893 300485 NP_001116855;NP_001116856;NP_001116857;NP_060215;XP_005272673;XP_005272674;XP_005272675;XP_005272676;XP_005272677;XP_006724599 NM_001123383;NM_001123384;NM_001123385;NM_001130139;NM_017745;NM_020926;XM_005272616;XM_005272617;XM_005272618;XM_005272619;XM_005272620;XM_006724536 ENSP00000367705 Q6W2J9 TRUE cgc 0 1 0 Eukaryotes 3 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chrX 39911365 39937182 |ANOP2|MAA2|MCOPS2| NP_001116857 0 FALSE 5 29 2287 0.2000 1
54894 RNF43 ring finger protein 43 17q22 7896 18505 612482 NP_060233 NM_017763 ENSP00000385328 Q68DV7 TRUE cgc 0 1 0 Eukaryotes 1 -1 chr17 56432307 56492938 |RNF124|URCC| NP_060233 0 FALSE 6 12 2167 0.0760 4
54904 WHSC1L1 Wolf-Hirschhorn syndrome candidate 1-like 1 8p11.2 6155 12767 607083 NP_060248;NP_075447;XP_005273604;XP_005273605 NM_017778;NM_023034;XM_005273547;XM_005273548 ENSP00000313983 Q9BZ95 TRUE cgc 1 0 0 Last Universal Common Ancestor 4 Cell cycle,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr8 38133162 38205689 |NSD3|pp14328| NP_075447 0 FALSE 1 44 12904 0.0410
54937 SOHLH2 spermatogenesis and oogenesis specific basic helix-loop-helix 2 13q13.3 7910 26026 - NP_001269076;NP_060296 NM_001282147;NM_017826 ENSP00000421868;ENSP00000451542 NA TRUE can 0 0 -1 Metazoans 0 Cellular metabolism,DNA/RNA metabolism and transcription,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Regulation of transcription - 0 0 |SPATA28|TEB1|bHLHe81| - -1 FALSE 1
54949 SDHAF2 succinate dehydrogenase complex assembly factor 2 11q12.2 - 26034 613019 NP_060311 NM_017841 ENSP00000301761;ENSP00000443130 Q9NX18 TRUE cgc 0 1 0 Last Universal Common Ancestor 2 -1 chr11 61205097 61213540 |C11orf79|PGL2|SDH5| NP_060311 0 FALSE 1 17 665 0.0740
54989 ZNF770 zinc finger protein 770 15q14 16918 26061 - NP_054825 NM_014106 ENSP00000348673 Q6IQ21 TRUE can 0 0 1 Eukaryotes 1 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr15 35273563 35275635 |PRO1914| NP_054825 1 FALSE 1 2 84 0.0000
55023 PHIP pleckstrin homology domain interacting protein 6q14 10152 15673 612870 NP_060404;XP_005248786 NM_017934;XM_005248729 ENSP00000275034 Q8WWQ0 TRUE can 0 0 0 Eukaryotes 3 Signal transduction chr6 79650413 79787785 |DCAF14|ndrp| NP_060404 0 FALSE 1 16 3259 0.1830
55055 ZWILCH zwilch kinetochore protein 15q22.31 7640 25468 609984 NP_001274750;NP_001274751;NP_001274752;NP_060445 NM_001287821;NM_001287822;NM_001287823;NM_017975;NR_003105 ENSP00000311429 Q9H900 TRUE can 0 0 0 Metazoans 0 Cell cycle chr15 66797677 66839014 |hZwilch| NP_060445 0 FALSE 1 4 35 0.1670 8
55117 SLC6A15 solute carrier family 6 (neutral amino acid transporter), member 15 12q21.3 12141 13621 607971 NP_001139807;NP_060527;NP_877499 NM_001146335;NM_018057;NM_182767 ENSP00000266682 Q9H2J7 TRUE can 0 0 0 Last Universal Common Ancestor 0 Cellular processes chr12 85255414 85285899 |NTT73|SBAT1|V7-3|hv7-3| NP_877499 0 FALSE 1 1 0 0.0000
55190 NUDT11 nudix (nucleoside diphosphate linked moiety X)-type motif 11 Xp11.22 6667 18011 300528 NP_060629 NM_018159 ENSP00000365160;ENSP00000469526 Q96G61 TRUE can 0 0 4 Last Universal Common Ancestor 0 -1 chrX 51238805 51239296 |DIPP3b|DIPP3beta|hDIPP3beta| NP_060629 4 FALSE 1 1 0 0.0000
55193 PBRM1 polybromo 1 3p21 - 30064 606083 NP_060783;XP_005265332;XP_005265336;XP_005265337;XP_005265339;XP_005265340;XP_005265345;XP_006713283;XP_006713284;XP_006713285;XP_006713286;XP_006713287;XP_006713288;XP_006713289;XP_006713290;XP_006713291;XP_006713292;XP_006713293;XP_006713294;XP_006713295;XP_006713296;XP_006713297 NM_018165;NM_018313;NM_181041;NM_181042;XM_005265275;XM_005265279;XM_005265280;XM_005265282;XM_005265283;XM_005265288;XM_006713220;XM_006713221;XM_006713222;XM_006713223;XM_006713224;XM_006713225;XM_006713226;XM_006713227;XM_006713228;XM_006713229;XM_006713230;XM_006713231;XM_006713232;XM_006713233;XM_006713234 ENSP00000378307 Q86U86 TRUE cgc 0 1 0 Eukaryotes 4 Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr3 52582082 52713742 |BAF180|PB1| XP_005265332 0 FALSE 6 31 21639 0.2000 8
55196 KIAA1551 KIAA1551 12p11.21 7691 25559 - NP_060639;XP_005253462;XP_006719162 NM_018169;XM_005253405;XM_006719099 ENSP00000310338 Q9HCM1 TRUE can 0 0 0 Vertebrates 2 -1 chr12 32133890 32145466 |C12orf35| NP_060639 0 FALSE 1 2 5 0.0000 1
55252 ASXL2 additional sex combs like transcriptional regulator 2 2p24.1 - 23805 612991 NP_060733;XP_006712102;XP_006712103 NM_018263;XM_006712039;XM_006712040 ENSP00000391447 Q76L83 TRUE can 0 0 0 Metazoans 2 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr2 25964901 26101091 |ASXH2| NP_060733 0 FALSE 1 7 868 0.0950
55294 FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase 4q31.3 5888 16712 606278 NP_001013433;NP_001243998;NP_060785;NP_361014 NM_001013415;NM_001257069;NM_018315;NM_033632 ENSP00000281708 Q969H0 TRUE cgc 0 1 0 Last Universal Common Ancestor 12 Cellular metabolism,Cellular processes chr4 153244036 153332955 |AGO|CDC4|FBW7|SEL-10|SEL10|hAgo|hCdc4| NP_361014 0 FALSE 10 117 71102 0.0720 10
55359 STYK1 serine/threonine/tyrosine kinase 1 12p13.2 15447 18889 611433 NP_060893;XP_005253474 NM_018423;XM_005253417 ENSP00000075503 Q6J9G0 TRUE can 0 0 0 Last Universal Common Ancestor 0 Cellular metabolism,Cellular processes chr12 10772746 10787217 |NOK|SuRTK106| NP_060893 0 FALSE 2 3 1 0.6670
55422 ZNF331 zinc finger protein 331 19q13.42 5827 15489 606043 NP_001073375;NP_001073376;NP_001240727;NP_001240728;NP_001240729;NP_001240730;NP_061025;XP_005259097;XP_006723322 NM_001079906;NM_001079907;NM_001253798;NM_001253799;NM_001253800;NM_001253801;NM_018555;XM_005259040;XM_006723259 ENSP00000253144 Q9NQX6 TRUE cgc 1 0 0 Eukaryotes 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr19 54074855 54081203 |ZNF361|ZNF463| NP_001073375 0 FALSE 1 8 525 0.1070
55503 TRPV6 transient receptor potential cation channel, subfamily V, member 6 7q34 5982 14006 606680 NP_061116;XP_006716106;XP_006716107;XP_006716108 NM_014274;NM_018646;XM_006716043;XM_006716044;XM_006716045 ENSP00000352358;ENSP00000456007 Q9H1D0 TRUE can 0 0 1 Eukaryotes 2 Cellular processes,Regulation of intracellular processes and metabolism chr7 142569463 142583261 |ABP/ZF|ECAC2|HSA277909|LP6728|ZFAB| NP_061116 1 FALSE 1 12 2132 0.0150 1
55511 SAGE1 sarcoma antigen 1 Xq26 2290 30369 300359 NP_061136;XP_006724827 NM_018666;XM_006724764 ENSP00000323191;ENSP00000468892 Q9NXZ1 TRUE can 0 0 1 Eukaryotes 0 -1 chrX 134978402 134995053 |CT14|SAGE| NP_061136 1 FALSE 1
55552 ZNF823 zinc finger protein 823 19p13.2 - 30936 - NP_001073962;XP_005260039;XP_006722852 NM_001080493;XM_005259982;XM_006722789 ENSP00000340683 P16415 TRUE can 0 0 -1 Eukaryotes 2 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription - 0 0 |HSZFP36| - -1 FALSE 1
55558 PLXNA3 plexin A3 Xq28 2062 9101 300022 NP_059984;XP_005274762;XP_005274763;XP_006724892;XP_006724893 NM_017514;XM_005274705;XM_005274706;XM_006724829;XM_006724830;XR_430556 ENSP00000358696;ENSP00000470631 P51805 TRUE can 0 0 0 Eukaryotes 1 Cell cycle,Cell motility and interactions,Development,Regulation of intracellular processes and metabolism,Signal transduction chrX 153688524 153701025 |6.3|HSSEXGENE|PLXN3|PLXN4|XAP-6| NP_059984 0 FALSE 1 6 258 0.0000 8
55561 CDC42BPG CDC42 binding protein kinase gamma (DMPK-like) 11q13.1 13013 29829 613991 NP_059995 NM_017525 ENSP00000345133 Q6DT37 TRUE can 0 0 0 Eukaryotes 0 Cellular metabolism,Cellular processes,Signal transduction chr11 64591948 64612041 |DMPK2|HSMDPKIN|KAPPA-200|MRCKG|MRCKgamma| NP_059995 0 FALSE 1 5 69 0.1000
55567 DNAH3 dynein, axonemal, heavy chain 3 16p12.3 4513 2949 603334 NP_060009;XP_006721125 NM_017539;XM_006721062 ENSP00000261383 Q8TD57 TRUE can 0 0 0 Eukaryotes 2 Cell motility and interactions,Cellular processes chr16 20944479 21170762 |DLP3|DNAHC3B|HEL-36|Hsadhc3| NP_060009 0 FALSE 1 1 0 0.0000
55582 KIF27 kinesin family member 27 9q21.32 11179 18632 611253 NP_001258856;NP_001258857;NP_060046;XP_005252146;XP_005252147;XP_005252148;XP_005252149;XP_006717239;XP_006717240;XP_006717241 NM_001271927;NM_001271928;NM_017576;XM_005252089;XM_005252090;XM_005252091;XM_005252092;XM_006717176;XM_006717177;XM_006717178;XR_242596;XR_242597 ENSP00000297814 Q86VH2 TRUE can 0 0 0 Eukaryotes 1 Cellular processes chr9 86451919 86530506 |NA| NP_060046 0 FALSE 1
55600 ITLN1 intelectin 1 (galactofuranose binding) 1q21.3 17165 18259 609873 NP_060095 NM_017625 ENSP00000323587 Q8WWA0 TRUE can 0 0 1 Metazoans 0 Cell response to stimuli,Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism,Signal transduction chr1 160846457 160854667 |INTL|ITLN|LFR|hIntL|omentin| NP_060095 1 FALSE 1 1 0 0.0000
55605 KIF21A kinesin family member 21A 12q12 10506 19349 608283 NP_001166934;NP_001166935;NP_001166936;NP_060111;XP_005269064;XP_005269065;XP_005269066;XP_005269067;XP_005269068;XP_005269069;XP_005269070;XP_005269071;XP_005269072;XP_006719556;XP_006719557;XP_006719558;XP_006719559 NM_001173463;NM_001173464;NM_001173465;NM_017641;XM_005269007;XM_005269008;XM_005269009;XM_005269010;XM_005269011;XM_005269012;XM_005269013;XM_005269014;XM_005269015;XM_006719493;XM_006719494;XM_006719495;XM_006719496;XR_429108 ENSP00000354878 Q7Z4S6 TRUE can 0 0 0 Eukaryotes 1 Cellular processes chr12 39688229 39836772 |CFEOM1|FEOM1|FEOM3A| XP_005269064 0 FALSE 1 10 2395 0.1560
55607 PPP1R9A protein phosphatase 1, regulatory subunit 9A 7q21.3 - 14946 602468 NP_001159632;NP_001159633;NP_001159634;NP_001159635;NP_060120;XP_005250542;XP_006716109;XP_006716110;XP_006716111 NM_001166160;NM_001166161;NM_001166162;NM_001166163;NM_017650;XM_005250485;XM_006716046;XM_006716047;XM_006716048 ENSP00000405514 Q9ULJ8 TRUE can 0 0 0 Metazoans 3 Development chr7 94539426 94919612 |NRB1|NRBI|Neurabin-I| NP_001159632 0 FALSE 1 11 404 0.1820
55613 MTMR8 myotubularin related protein 8 Xq11.2 6664 16825 - NP_060147 NM_017677 ENSP00000355195;ENSP00000363985 Q96EF0 TRUE can 0 0 0 Eukaryotes 0 Cellular metabolism,Cellular processes chrX 63488420 63579407 |NA| NP_060147 0 FALSE 1 1 0 0.0000
55614 KIF16B kinesin family member 16B 20p11.23 10731 15869 - NP_001186794;NP_001186795;NP_078980;XP_005260807;XP_005260808;XP_005260809;XP_005260810;XP_005260811;XP_005260812;XP_006723651 NM_001199865;NM_001199866;NM_024704;XM_005260750;XM_005260751;XM_005260752;XM_005260753;XM_005260754;XM_005260755;XM_006723588 ENSP00000384164 Q96L93 TRUE can 0 0 0 Eukaryotes 6 Cellular processes chr20 16347794 16509087 |C20orf23|KISC20ORF|SNX23| XP_005260807 0 FALSE 1 1 0 0.0000
55636 CHD7 chromodomain helicase DNA binding protein 7 8q12.2 10595 20626 608892 NP_060250;XP_005251323;XP_005251324;XP_006716522;XP_006716523 NM_017780;XM_005251266;XM_005251267;XM_006716459;XM_006716460 ENSP00000392028 Q9P2D1 TRUE can 0 0 0 Last Universal Common Ancestor 3 Cell cycle,Cell response to stimuli,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Regulation of transcription chr8 61653992 61778489 |HH5|IS3|KAL5| NP_060250 0 FALSE 1 27 2204 0.2340
55698 RADIL Ras association and DIL domains 7p22.1 7663 22226 611491 NP_060529 NM_018059 ENSP00000382492 Q96JH8 TRUE can 0 0 0 Eukaryotes 2 Signal transduction chr7 4839012 4917770 |RASIP2| NP_060529 0 FALSE 1 27 6611 0.0260
55729 ATF7IP activating transcription factor 7 interacting protein 12p13.1 9811 20092 613644 NP_001273443;NP_001273444;NP_060649;NP_851997;XP_005253481;XP_006719171;XP_006719172 NM_001286514;NM_001286515;NM_018179;NM_181352;XM_005253424;XM_006719108;XM_006719109 ENSP00000261168 Q6VMQ6 TRUE can 0 0 0 Metazoans 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr12 14576841 14651004 |ATF-IP|MCAF1|p621| NP_851997 0 FALSE 1 75 70634 0.0260 4
55754 TMEM30A transmembrane protein 30A 6q14.1 15535 16667 611028 NP_001137430;NP_060717 NM_001143958;NM_018247 ENSP00000230461 Q9NV96 TRUE can 0 0 0 Eukaryotes 6 -1 chr6 75965821 75994354 |C6orf67|CDC50A| NP_060717 0 FALSE 1 10 118908 0.0000
55759 WDR12 WD repeat domain 12 2q33.2 - 14098 - NP_060726 NM_018256 ENSP00000261015 Q9GZL7 TRUE can 0 0 3 Eukaryotes 1 Signal transduction chr2 203745586 203776199 |YTM1| NP_060726 3 FALSE 1 33 13353 0.0870
55770 EXOC2 exocyst complex component 2 6p25.3 11544 24968 615329 NP_060773;XP_006715204;XP_006715205 NM_018303;NR_073064;XM_006715141;XM_006715142 ENSP00000230449 Q96KP1 TRUE can 0 0 0 Eukaryotes 3 Cellular processes chr6 486674 637818 |SEC5|SEC5L1|Sec5p| NP_060773 0 FALSE 1 23 7282 0.1580 5
55821 ALLC allantoicase 2q35 10642 17377 612396 NP_060906;XP_005263908;XP_006711954 NM_018436;NM_199232;XM_005263851;XM_006711891 ENSP00000252505 Q8N6M5 TRUE can 0 0 0 Last Universal Common Ancestor 0 -1 chr2 3721665 3750150 |ALC| NP_060906 0 FALSE 1
55824 PAG1 phosphoprotein membrane anchor with glycosphingolipid microdomains 1 8q21.13 5772 30043 605767 NP_060910;XP_006716524;XP_006716525 NM_018440;XM_006716461;XM_006716462 ENSP00000220597 Q9NWQ8 TRUE can 0 0 0 Vertebrates 5 Immune system response,Regulation of intracellular processes and metabolism,Signal transduction chr8 81888782 81905462 |NA| NP_060910 0 FALSE 1 20 1937 0.4370 1
55914 ERBB2IP erbb2 interacting protein 5q12.3 6090 15842 606944 NP_001006600;NP_001240626;NP_001240627;NP_001240628;NP_001240630;NP_061165;XP_005248611;XP_005248612;XP_005248613;XP_006714723 NM_001006600;NM_001253697;NM_001253698;NM_001253699;NM_001253701;NM_018695;XM_005248554;XM_005248555;XM_005248556;XM_006714660 ENSP00000370330 Q96RT1 TRUE can 0 0 0 Last Universal Common Ancestor 9 Cell cycle,Cellular processes,Development,Signal transduction chr5 65288547 65374355 |ERBIN|HEL-S-78| XP_005248611 0 FALSE 1 69 66634 0.0420 4
55966 AJAP1 adherens junctions associated protein 1 1p36.32 15339 30801 610972 NP_001035943;NP_061324 NM_001042478;NM_018836 ENSP00000367432 Q9UKB5 TRUE can 0 0 0 Vertebrates 0 -1 chr1 4771958 4834556 |MOT8|SHREW-1|SHREW1| NP_001035943 0 FALSE 1 2 0 1.0000 1
56034 PDGFC platelet derived growth factor C 4q32 - 8801 608452 NP_057289;XP_006714336 NM_016205;NR_036641;XM_006714273 ENSP00000422464 Q9NRA1 TRUE can 0 0 0 Vertebrates 7 Development chr4 157684245 157892055 |FALLOTEIN|SCDGF| NP_057289 0 FALSE 1 7 457 0.1430
56097 PCDHGC5 protocadherin gamma subfamily C, 5 5q31 7318 8718 606306 NP_061752;NP_115783 NM_018929;NM_032407 ENSP00000252087;ENSP00000312070 Q9Y5F6 TRUE can 0 0 4 Eukaryotes 1 Cell motility and interactions chr5 140734675 140890737 |PCDH-GAMMA-C5| NP_061740 4 FALSE 1 1 0 0.0000
56128 PCDHB8 protocadherin beta 8 5q31 7563 8693 606334 NP_061993 NM_019120 ENSP00000239444 Q9UN66 TRUE can 0 0 10 Eukaryotes 3 Cell motility and interactions chr5 140557616 140560018 |PCDH-BETA8|PCDH3I| NP_061993 10 FALSE 1 1 0 0.0000
56130 PCDHB6 protocadherin beta 6 5q31 7561 8691 606332 NP_061762 NM_018939 ENSP00000231136 Q9Y5E3 TRUE can 0 0 13 Eukaryotes 0 Cell motility and interactions,Development,Multicellular activities chr5 140529839 140532220 |PCDH-BETA6| NP_061762 13 FALSE 1
56136 PCDHA13 protocadherin alpha 13 5q31 7554 8667 606319 NP_061727;NP_114071 NM_018904;NM_031865 ENSP00000289272 Q9Y5I0 TRUE can 0 0 -1 Eukaryotes 0 Cell motility and interactions - 0 0 |CNR5|CNRN5|CNRS5|CRNR5|PCDH-ALPHA13| - -1 FALSE 1
56171 DNAH7 dynein, axonemal, heavy chain 7 2q32.3 10914 18661 610061 NP_061720 NM_018897 ENSP00000311273 Q8WXX0 TRUE can 0 0 0 Eukaryotes 0 Cell motility and interactions,Cellular processes chr2 196602648 196922843 |NA| NP_061720 0 FALSE 1 2 14 0.0000
56302 TRPV5 transient receptor potential cation channel, subfamily V, member 5 7q35 5981 3145 606679 NP_062815 NM_019841 ENSP00000265310;ENSP00000457041 Q9NQA5 TRUE can 0 0 1 Eukaryotes 0 Cellular metabolism,Cellular processes chr7 142605683 142630556 |ECAC1|OTRPC3| NP_062815 1 FALSE 1 5 142 0.1000 1
56339 METTL3 methyltransferase like 3 14q11.1 14389 17563 612472 NP_062826;XP_006720269 NM_019852;XM_006720206 ENSP00000298717 Q86U44 TRUE can 0 0 0 Last Universal Common Ancestor 0 Cellular metabolism,DNA/RNA metabolism and transcription chr14 21966405 21979365 |IME4|MT-A70|Spo8| NP_062826 0 FALSE 1 3 1424 0.3330
56652 C10orf2 chromosome 10 open reading frame 2 10q24 5830 1160 606075 NP_001157284;NP_001157285;NP_001157286;NP_068602;XP_006717984;XP_006717985 NM_001163812;NM_001163813;NM_001163814;NM_021830;XM_006717921;XM_006717922;XR_246100 ENSP00000309595;ENSP00000432279 Q96RR1 TRUE can 0 0 0 Last Universal Common Ancestor 4 Cellular metabolism,DNA/RNA metabolism and transcription chr10 102747968 102753264 |IOSCA|MTDPS7|PEO1|PEOA3|TWINL| NP_068602 0 FALSE 1 6 427 0.0670
56776 FMN2 formin 2 1q43 10449 14074 606373 NP_064450;XP_005273257 NM_020066;XM_005273200 ENSP00000318884 Q9NZ56 TRUE can 0 0 0 Eukaryotes 0 Cell cycle,Cellular processes,DNA/RNA metabolism and transcription,Development,Multicellular activities chr1 240255410 240635753 |NA| XP_005273257 0 FALSE 3
56853 CELF4 CUGBP, Elav-like family member 4 18q12 12534 14015 612679 NP_001020258;NP_001020259;NP_001020260;NP_064565;XP_005258365;XP_006722567;XP_006722568;XP_006722569;XP_006722570;XP_006722571;XP_006722572 NM_001025087;NM_001025088;NM_001025089;NM_020180;XM_005258308;XM_006722504;XM_006722505;XM_006722506;XM_006722507;XM_006722508;XM_006722509 ENSP00000355089 Q9BZC1 TRUE can 0 0 0 Eukaryotes 1 Cell cycle,Development chr18 34833777 35145604 |BRUNOL-4|BRUNOL4| NP_064565 0 FALSE 1 2 142 0.0000
56884 FSTL5 follistatin-like 5 4q32.3 10998 21386 - NP_001121899;NP_001121900;NP_064501 NM_001128427;NM_001128428;NM_020116 ENSP00000305334 Q8N475 TRUE can 0 0 0 Metazoans 0 -1 chr4 162306902 163032548 |NA| NP_064501 0 FALSE 2 1 0 0.0000
56979 PRDM9 PR domain containing 9 5p14 17905 13994 609760 NP_064612 NM_020227 ENSP00000296682 Q9NQV7 TRUE can 0 0 0 Eukaryotes 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr5 23509579 23527879 |MEISETZ|MSBP3|PFM6|PRMD9|ZNF899| NP_064612 0 FALSE 3
56999 ADAMTS9 ADAM metallopeptidase with thrombospondin type 1 motif, 9 3p14.1 5662 13202 605421 NP_891550;XP_005265386 NM_182920;XM_005265329;XR_245151 ENSP00000418735 Q9P2N4 TRUE can 0 0 0 Eukaryotes 1 Cellular metabolism chr3 64507850 64673333 |NA| NP_891550 0 FALSE 1 1 0 0.0000
57007 ACKR3 atypical chemokine receptor 3 2q37.3 9882 23692 610376 NP_064707;XP_005246154;XP_005246155;XP_006712703 NM_001047841;NM_020311;XM_005246097;XM_005246098;XM_006712640 ENSP00000272928 P25106 TRUE cgc 1 0 0 Metazoans 2 Signal transduction chr2 237489109 237490194 |CMKOR1|CXC-R7|CXCR-7|CXCR7|GPR159| NP_064707 0 FALSE 1 3 209 0.0000 3
57016 AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase) 7q33 5271 382 604707 NP_064695;XP_005250563;XP_006716123 NM_020299;XM_005250506;XM_006716060 ENSP00000261636;ENSP00000352584 O60218 TRUE can 0 0 2 Last Universal Common Ancestor 5 Cellular metabolism chr7 134212664 134223770 |AKR1B11|AKR1B12|ALDRLn|ARL-1|HSI| NP_064695 2 FALSE 1 3 19 0.0000
57018 CCNL1 cyclin L1 3q25.31 10814 20569 613384 NP_064703;XP_005247704;XP_005247705;XP_005247706;XP_005247707;XP_005247708;XP_006713773;XP_006713774 NM_020307;XM_005247647;XM_005247648;XM_005247649;XM_005247650;XM_005247651;XM_006713710;XM_006713711 ENSP00000265056;ENSP00000307288 Q9UK58 TRUE can 0 0 0 Last Universal Common Ancestor 7 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr3 156866033 156877883 |ANIA6A|PRO1073|ania-6a| NP_064703 0 FALSE 1 7 712 0.0480
57082 CASC5 cancer susceptibility candidate 5 15q14 10634 24054 609173 NP_653091;NP_733468 NM_144508;NM_170589 ENSP00000335463 Q8NG31 TRUE cgc 1 0 0 Vertebrates 3 Cell cycle,Development,Multicellular activities chr15 40897309 40954383 |AF15Q14|CT29|D40|KNL1|PPP1R55|Spc7|hKNL-1|hSpc105| NP_733468 0 FALSE 1 12 823 0.3030 11
57088 PLSCR4 phospholipid scramblase 4 3q24 7401 16497 607612 NP_001121776;NP_001121777;NP_001121778;NP_001170775;NP_065086;XP_005247711;XP_005247712 NM_001128304;NM_001128305;NM_001128306;NM_001177304;NM_020353;XM_005247654;XM_005247655 ENSP00000347038 Q9NRQ2 TRUE can 0 0 0 Eukaryotes 8 Cellular processes,Multicellular activities chr3 145912201 145938713 |NA| NP_001121776 0 FALSE 1 7 264 0.1900
57120 GOPC golgi-associated PDZ and coiled-coil motif containing 6q21 6024 17643 606845 NP_001017408;NP_065132 NM_001017408;NM_020399 ENSP00000357484 Q9HD26 TRUE cgc 1 0 0 Metazoans 3 Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism chr6 117884420 117923451 |GOPC1|PIST|dJ94G16.2| NP_065132 0 FALSE 2 70 113131 0.0110 4
57152 SLURP1 secreted LY6/PLAUR domain containing 1 8q24.3 5836 18746 606119 NP_065160 NM_020427 ENSP00000246515 P55000 TRUE can 0 0 0 Mammals 0 -1 chr8 143822564 143823803 |ANUP|ArsB|LY6LS|MDM| NP_065160 0 FALSE 1
57188 ADAMTSL3 ADAMTS-like 3 15q25.2 12426 14633 609199 NP_997400;XP_005272492;XP_005272493;XP_005272494 NM_207517;XM_005272435;XM_005272436;XM_005272437 ENSP00000286744 P82987 TRUE can 0 0 0 Last Universal Common Ancestor 0 -1 chr15 84324514 84706555 |ADAMTSL-3| NP_997400 0 FALSE 2 3 59 0.0000
57194 ATP10A ATPase, class V, type 10A 15q11.2 - 13542 605855 NP_077816;XP_005268318;XP_006720682 NM_024490;XM_005268261;XM_006720619 ENSP00000349325 O60312 TRUE can 0 0 0 Last Universal Common Ancestor 1 Cellular processes,Development,Regulation of intracellular processes and metabolism chr15 25924491 26108243 |ATP10C|ATPVA|ATPVC| NP_077816 0 FALSE 2
57282 SLC4A10 solute carrier family 4, sodium bicarbonate transporter, member 10 2q24.2 - 13811 605556 NP_001171486;NP_001171487;NP_071341;XP_005246750;XP_005246751;XP_005246752;XP_005246753;XP_006712704;XP_006712705;XP_006712706 NM_001178015;NM_001178016;NM_022058;XM_005246693;XM_005246694;XM_005246695;XM_005246696;XM_006712641;XM_006712642;XM_006712643 ENSP00000393066 Q6U841 TRUE can 0 0 0 Last Universal Common Ancestor 1 Cellular processes chr2 162480831 162839752 |NBCn2|NCBE| XP_005246750 0 FALSE 1 3 39 0.0000
57451 TENM2 teneurin transmembrane protein 2 5q34 - 29943 610119 NP_001116151;XP_005266007;XP_005266009;XP_006714960;XP_006714961 NM_001080428;NM_001122679;XM_005265950;XM_005265952;XM_006714897;XM_006714898 ENSP00000429430 NA TRUE can 0 0 0 Last Universal Common Ancestor 1 -1 chr5 166711843 167689812 |ODZ2|TEN-M2|TNM2| NP_001116151 0 FALSE 1
57486 NLN neurolysin (metallopeptidase M3 family) 5q12.3 7495 16058 611530 NP_065777;XP_005248616;XP_006714724 NM_020726;XM_005248559;XM_006714661 ENSP00000370372 Q9BYT8 TRUE can 0 0 0 Last Universal Common Ancestor 0 Cellular metabolism chr5 65054386 65118740 |AGTBP|EP24.16| NP_065777 0 FALSE 1 2 2650 0.0000
57492 ARID1B AT rich interactive domain 1B (SWI1-like) 6q25.1 10660 18040 614556 NP_059989;NP_065783;XP_005267126;XP_006715586;XP_006715587;XP_006715588;XP_006715589;XP_006715590 NM_017519;NM_020732;XM_005267069;XM_006715523;XM_006715524;XM_006715525;XM_006715526;XM_006715527 ENSP00000344546 Q8NFD5 TRUE can 0 0 0 Metazoans 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr6 157098983 157529022 |6A3-5|BAF250B|DAN15|ELD/OSA1|MRD12|OSA2|P250R| XP_005267126 0 FALSE 4 24 1252 0.2970 9
57521 RPTOR regulatory associated protein of MTOR, complex 1 17q25.3 6184 30287 607130 NP_001156506;NP_065812 NM_001163034;NM_020761 ENSP00000307272 Q8N122 TRUE can 0 0 0 Eukaryotes 0 -1 chr17 78519430 78938127 |KOG1|Mip1| NP_065812 0 FALSE 1 72 18081 0.0920 21
57529 RGAG1 retrotransposon gag domain containing 1 Xq23 6600 29245 - NP_065820 NM_020769 ENSP00000419786 Q8NET4 TRUE can 0 0 0 Eukaryotes 0 -1 chrX 109693846 109698546 |MAR9|MART9| NP_065820 0 FALSE 1 2 19 0.0000
57537 SORCS2 sortilin-related VPS10 domain containing receptor 2 4p16.1 12099 16698 606284 NP_065828;XP_005248044 NM_020777;XM_005247987 ENSP00000422185 Q96PQ0 TRUE can 0 0 0 Eukaryotes 0 Signal transduction chr4 7194374 7741988 |NA| NP_065828 0 FALSE 1 4 26 0.3330
57554 LRRC7 leucine rich repeat containing 7 1p31.1 9930 18531 614453 NP_065845;XP_006710845 NM_020794;XM_006710782 ENSP00000035383 Q96NW7 TRUE can 0 0 0 Last Universal Common Ancestor 0 -1 chr1 70225888 70587567 |DENSIN| NP_065845 0 FALSE 2 14 1020 0.1320 3
57591 MKL1 megakaryoblastic leukemia (translocation) 1 22q13 10445 14334 606078 NP_001269589;NP_001269590;NP_001269591;NP_065882;XP_005261748;XP_005261749;XP_005261751 NM_001282660;NM_001282661;NM_001282662;NM_020831;XM_005261691;XM_005261692;XM_005261694 ENSP00000283635;ENSP00000310880;ENSP00000347847 Q969V6 TRUE cgc 1 0 0 Metazoans 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr22 40807397 40929639 |BSAC|MRTF-A| XP_005261748 0 FALSE 1 15 1824 0.2290 3
57592 ZNF687 zinc finger protein 687 1q21.3 13859 29277 610568 NP_065883;XP_005245423;XP_005245425 NM_020832;XM_005245366;XM_005245368 ENSP00000319829 Q8N1G0 TRUE can 0 0 0 Eukaryotes 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr1 151258750 151263682 |NA| XP_005245423 0 FALSE 1 13 744 0.2690 1
57616 TSHZ3 teashirt zinc finger homeobox 3 19q12 18351 30700 614119 NP_065907 NM_020856 ENSP00000240587 Q63HK5 TRUE can 0 0 0 Metazoans 2 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr19 31767456 31770662 |TSH3|ZNF537| NP_065907 0 FALSE 1 18 3453 0.0390 1
57619 SHROOM3 shroom family member 3 4q21.1 7053 30422 604570 NP_065910;XP_005263219;XP_005263220;XP_005263221;XP_005263222;XP_006714345 NM_020859;XM_005263162;XM_005263163;XM_005263164;XM_005263165;XM_006714282 ENSP00000296043 Q8TF72 TRUE can 0 0 0 Metazoans 1 Cellular processes,Development,Regulation of intracellular processes and metabolism chr4 77357206 77700327 |APXL3|SHRM|ShrmL| NP_065910 0 FALSE 1 9 504 0.0000
57663 USP29 ubiquitin specific peptidase 29 19q13.43 7163 18563 609546 NP_065954 NM_020903 ENSP00000254181 Q9HBJ7 TRUE can 0 0 0 Eukaryotes 1 Cellular metabolism,Cellular processes chr19 57640044 57642809 |HOM-TES-84/86| NP_065954 0 FALSE 1 3 64 0.0000
57670 KIAA1549 KIAA1549 7q34 - 22219 613344 NP_001158137;NP_065961;XP_006716134;XP_006716135 NM_001164665;NM_020910;XM_006716071;XM_006716072 ENSP00000416040 Q9HCM3 TRUE cgc 1 0 0 Vertebrates 3 -1 chr7 138522654 138666015 |NA| NP_001158137 0 FALSE 1 12 1578 0.0450
57674 RNF213 ring finger protein 213 17q25.3 10716 14539 613768 NP_001243000;NP_066005;XP_005257602;XP_005257603;XP_006722058 NM_001256071;NM_020914;NM_020954;XM_005257545;XM_005257546;XM_006721995;XR_243676 ENSP00000324392 Q63HN8 TRUE cgc 1 0 0 Vertebrates 3 -1 chr17 78237481 78367295 |ALO17|C17orf27|KIAA1618|MYMY2|MYSTR|NET57| XP_005257602 0 FALSE 1 14 7216 0.0550
57678 GPAM glycerol-3-phosphate acyltransferase, mitochondrial 10q25.2 3865 24865 602395 NP_001231878;NP_065969;XP_005270055;XP_005270056;XP_005270057 NM_001244949;NM_020918;XM_005269998;XM_005269999;XM_005270000 ENSP00000265276 Q9HCL2 TRUE can 0 0 0 Last Universal Common Ancestor 9 Cellular metabolism chr10 113913311 113941542 |GPAT1| NP_001231878 0 FALSE 1 1 0 0.0000
57683 ZDBF2 zinc finger, DBF-type containing 2 2q33.3 - 29313 - NP_001272478;NP_065974;XP_005246768;XP_005246769;XP_005246770;XP_006712719;XP_006712720;XP_006712721 NM_001285549;NM_020923;XM_005246711;XM_005246712;XM_005246713;XM_006712656;XM_006712657;XM_006712658 ENSP00000363545 Q9HCK1 TRUE can 0 0 0 Vertebrates 0 -1 chr2 207146574 207176314 |NA| NP_065974 0 FALSE 1 2 21 0.0000
57721 METTL14 methyltransferase like 14 4q26 13879 29330 - NP_066012;XP_005263223;XP_006714346 NM_020961;XM_005263166;XM_006714283 ENSP00000373474 Q9HCE5 TRUE can 0 0 0 Eukaryotes 0 Cellular metabolism,DNA/RNA metabolism and transcription chr4 119606690 119631454 |NA| NP_066012 0 FALSE 1 4 25 0.1670
57724 EPG5 ectopic P-granules autophagy protein 5 homolog (C. elegans) 18q12.3 11157 29331 615068 NP_066015;XP_005258380;XP_005258381;XP_006722579;XP_006722580 NM_020964;XM_005258323;XM_005258324;XM_006722516;XM_006722517 ENSP00000282041 Q9HCE0 TRUE can 0 0 0 Eukaryotes 0 -1 chr18 43432435 43547205 |HEEW1|KIAA1632|VICIS|hEPG5| NP_066015 0 FALSE 1 1 0 0.0000
57731 SPTBN4 spectrin, beta, non-erythrocytic 4 19q13.13 9372 14896 606214 NP_066022;NP_079489;XP_006723369 NM_020971;NM_025213;XM_006723306 ENSP00000263373 Q9H254 TRUE can 0 0 0 Eukaryotes 0 Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism chr19 40978529 41081472 |QV|SPNB4|SPTBN3| NP_066022 0 FALSE 1 12 1160 0.0150 5
57820 CCNB1IP1 cyclin B1 interacting protein 1, E3 ubiquitin protein ligase 14q11.2 7000 19437 608249 NP_067001;NP_878269;NP_878272 NM_021178;NM_182849;NM_182851;NM_182852 ENSP00000337396 Q9NPC3 TRUE cgc 1 0 2 Eukaryotes 1 -1 chr14 20779712 20784682 |C14orf18|HEI10| NP_067001 2 FALSE 1 9 2492 0.0280
58508 KMT2C lysine (K)-specific methyltransferase 2C 7q36.1 6016 13726 606833 NP_733751;XP_005250082;XP_005250083;XP_005250084;XP_005250085;XP_005250088;XP_006716140;XP_006716141;XP_006716142 NM_021230;NM_170606;XM_005250025;XM_005250026;XM_005250027;XM_005250028;XM_005250031;XM_006716077;XM_006716078;XM_006716079;XR_428183 ENSP00000262189 Q8NEZ4 TRUE cgc 0 1 0 Last Universal Common Ancestor 4 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction chr7 151833920 152132871 |HALR|MLL3| XP_005250082 0 FALSE 9 21 2948 0.2520 5
60494 CCDC81 coiled-coil domain containing 81 11q14.2 8032 26281 - NP_001149946;NP_068599;XP_005274218;XP_005274219 NM_001156474;NM_021827;XM_005274161;XM_005274162 ENSP00000415528 Q6ZN84 TRUE can 0 0 0 Metazoans 0 -1 chr11 86086206 86133754 |NA| NP_001149946 0 FALSE 1
63035 BCORL1 BCL6 corepressor-like 1 Xq25-q26.1 6517 25657 300688 NP_068765;XP_005262509;XP_005262510;XP_005262511;XP_005262512;XP_005262513;XP_006724839;XP_006724840;XP_006724841;XP_006724842 NM_001184772;NM_021946;XM_005262452;XM_005262453;XM_005262454;XM_005262455;XM_005262456;XM_006724776;XM_006724777;XM_006724778;XM_006724779 ENSP00000218147 Q5H9F3 TRUE can 0 0 0 Metazoans 1 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chrX 129139208 129190108 |BCoR-L1|CXorf10| XP_005262509 0 FALSE 1 9 74 0.3610
63895 PIEZO2 piezo-type mechanosensitive ion channel component 2 18p11.22 7636 26270 613629 NP_071351 NM_022068;NM_173817 ENSP00000463094 Q9H5I5 TRUE can 0 0 0 Eukaryotes 0 -1 chr18 10671527 11148587 |C18orf30|C18orf58|DA3|DA5|FAM38B|FAM38B2|HsT748|HsT771|MWKS| NP_071351 0 FALSE 1
63923 TNN tenascin N 1q23-q24 - 22942 - NP_071376 NM_022093 ENSP00000239462 Q9UQP3 TRUE can 0 0 0 Last Universal Common Ancestor 0 Cell cycle,Cell motility and interactions,Development,Signal transduction chr1 175046555 175116204 |TN-W| NP_071376 0 FALSE 1 3 12 0.0000
63973 NEUROG2 neurogenin 2 4q25 6976 13805 606624 NP_076924 NM_024019 ENSP00000317333 Q9H2A3 TRUE can 0 0 0 Vertebrates 0 Cell cycle,Cell motility and interactions,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription chr4 113435816 113436631 |Atoh4|Math4A|NGN2|bHLHa8|ngn-2| NP_076924 0 FALSE 1 2 11 0.0000
63976 PRDM16 PR domain containing 16 1p36.23-p33 16122 14000 605557 NP_071397;NP_955533;XP_005244829;XP_005244830;XP_005244831;XP_006710877 NM_022114;NM_199454;XM_005244772;XM_005244773;XM_005244774;XM_006710814 ENSP00000270722 Q9HAZ2 TRUE cgc 1 0 0 Eukaryotes 4 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr1 3102691 3350372 |CMD1LL|LVNC8|MEL1|PFM13| XP_005244829 0 FALSE 1 5 132 0.3000
64005 MYO1G myosin IG 7p13-p11.2 17622 13880 600642 NP_149043 NM_033054 ENSP00000258787 B0I1T2 TRUE can 0 0 0 Eukaryotes 0 -1 chr7 45002341 45018560 |MHAG| NP_149043 0 FALSE 1 4 32 0.0000
64072 CDH23 cadherin-related 23 10q22.1 5699 13733 605516 NP_001165401;NP_001165402;NP_001165403;NP_001165404;NP_001165405;NP_001165406;NP_001165407;NP_071407;NP_443068;XP_006718003;XP_006718004;XP_006718005 NM_001171930;NM_001171931;NM_001171932;NM_001171933;NM_001171934;NM_001171935;NM_001171936;NM_022124;NM_052836;XM_006717940;XM_006717941;XM_006717942 ENSP00000381768 Q9H251 TRUE can 0 0 0 Eukaryotes 0 Cell motility and interactions,Cell response to stimuli,Multicellular activities,Regulation of intracellular processes and metabolism chr10 73199589 73575032 |CDHR23|USH1D| NP_071407 0 FALSE 1 3 360 0.3330
64084 CLSTN2 calsyntenin 2 3q23 - 17448 611323 NP_071414 NM_022131 ENSP00000402460 Q9H4D0 TRUE can 0 0 0 Metazoans 1 Cell motility and interactions chr3 139654217 140285092 |ALC-GAMMA|CDHR13|CS2|CSTN2|alcagamma| NP_071414 0 FALSE 1
64109 CRLF2 cytokine receptor-like factor 2 Xp22.3; Yp11.3 2288 14281 300357 NP_001012288;NP_071431 NM_001012288;NM_022148 ENSP00000370979 Q9HC73 TRUE cgc 1 0 1 Vertebrates 0 -1 chrX 1314893 1331527 |CRLF2Y|TSLPR| NP_071431 1 FALSE 1 3 3 0.3330
64241 ABCG8 ATP-binding cassette, sub-family G (WHITE), member 8 2p21 5679 13887 605460 NP_071882;XP_005264540;XP_006712138 NM_022437;XM_005264483;XM_006712075 ENSP00000272286 Q9H221 TRUE can 0 0 0 Last Universal Common Ancestor 4 -1 chr2 44066193 44105049 |GBD4| NP_071882 0 FALSE 1 8 807 0.0000
64324 NSD1 nuclear receptor binding SET domain protein 1 5q35 9455 14234 606681 NP_071900;NP_758859;XP_005266016;XP_005266017;XP_005266018;XP_005266019;XP_006714964;XP_006714965;XP_006714966;XP_006714967 NM_022455;NM_172349;XM_005265959;XM_005265960;XM_005265961;XM_005265962;XM_006714901;XM_006714902;XM_006714903;XM_006714904 ENSP00000395929 Q96L73 TRUE cgc 1 0 0 Last Universal Common Ancestor 0 Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr5 176562105 176722457 |ARA267|KMT3B|SOTOS|SOTOS1|STO| NP_071900 0 FALSE 2 28 2411 0.0820
64403 CDH24 cadherin 24, type 2 14q11.2 13019 14265 - NP_071923;NP_659422 NM_022478;NM_144985 ENSP00000274170 Q86UP0 TRUE can 0 0 0 Eukaryotes 0 Cell motility and interactions chr14 23517192 23524942 |CDH11L| NP_071923 0 FALSE 1 5 266 0.4000 1
64478 CSMD1 CUB and Sushi multiple domains 1 8p23.2 10523 14026 608397 NP_150094 NM_033225 ENSP00000441462 Q96PZ7 TRUE can 0 0 0 Eukaryotes 0 -1 chr8 2796110 4851938 |PPP1R24| NP_150094 0 TRUE 1 3 147 0.0000
64750 SMURF2 SMAD specific E3 ubiquitin protein ligase 2 17q22-q23 - 16809 605532 NP_073576;XP_005257642 NM_022739;XM_005257585 ENSP00000262435;ENSP00000461327 Q9HAU4 TRUE can 0 0 1 Eukaryotes 3 Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction chr17 62541969 62657998 |NA| NP_073576 1 FALSE 1 142 118995 0.0380 19
64764 CREB3L2 cAMP responsive element binding protein 3-like 2 7q34 16391 23720 608834 NP_001240704;NP_919047;XP_005250598 NM_001253775;NM_194071;XM_005250541 ENSP00000329140 Q70SY1 TRUE cgc 1 0 0 Opisthokonts 5 Cell response to stimuli,Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr7 137565225 137686451 |BBF2H7| NP_919047 0 FALSE 1 10 4206 0.0670
64783 RBM15 RNA binding motif protein 15 1p13 5832 14959 606077 NP_001188474;NP_073605 NM_001201545;NM_022768 ENSP00000358799;ENSP00000364912 Q96T37 TRUE cgc 1 0 1 Eukaryotes 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr1 110882028 110888228 |OTT|OTT1| NP_073605 1 FALSE 1 25 4232 0.1500 1
64784 CRTC3 CREB regulated transcription coactivator 3 15q26.1 13384 26148 608986 NP_001036039;NP_073606;XP_005255025 NM_001042574;NM_022769;XM_005254968 ENSP00000268184 Q6UUV7 TRUE cgc 1 0 0 Metazoans 6 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr15 91073304 91185369 |TORC-3|TORC3| NP_073606 0 FALSE 1 4 127 0.1670
64901 RANBP17 RAN binding protein 17 5q34 5847 14428 606141 NP_075048 NM_022897 ENSP00000427975 Q9H2T7 TRUE cgc 1 0 0 Eukaryotes 0 Cellular processes,DNA/RNA metabolism and transcription chr5 170305101 170725859 |NA| NP_075048 0 FALSE 1 7 2525 0.0950
64919 BCL11B B-cell CLL/lymphoma 11B (zinc finger protein) 14q32.2 5950 13222 606558 NP_001269166;NP_001269167;NP_075049;NP_612808 NM_001282237;NM_001282238;NM_022898;NM_138576 ENSP00000349723 Q9C0K0 TRUE cgc 1 0 0 Eukaryotes 8 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr14 99640491 99737555 |ATL1-alpha|ATL1-beta|ATL1-delta|ATL1-gamma|CTIP-2|CTIP2|ZNF856B|hRIT1-alpha| NP_612808 0 FALSE 1 17 243 0.4260 1
65057 ACD adrenocortical dysplasia homolog (mouse) 16q22.1 12417 25070 609377 NP_001075955;NP_001075956;NP_075065;XP_005256172 NM_001082486;NM_001082487;NM_022914;XM_005256115;XR_429727;XR_429728 ENSP00000260116;ENSP00000299427;ENSP00000377496 Q96AP0 TRUE can 0 0 0 Vertebrates 2 DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism chr16 67691512 67694381 |PTOP|TINT1| NP_001075955 0 FALSE 1 67 49466 0.0830 9
65217 PCDH15 protocadherin-related 15 10q21.1 5698 14674 605514 NP_001136235;NP_001136236;NP_001136237;NP_001136238;NP_001136239;NP_001136240;NP_001136241;NP_001136242;NP_001136243;NP_001136244;NP_001136245;NP_149045;XP_006718013 NM_001142763;NM_001142764;NM_001142765;NM_001142766;NM_001142767;NM_001142768;NM_001142769;NM_001142770;NM_001142771;NM_001142772;NM_001142773;NM_033056;XM_006717950 ENSP00000354950 Q96QU1 TRUE can 0 0 0 Eukaryotes 0 Cell motility and interactions,Cell response to stimuli,Multicellular activities,Regulation of intracellular processes and metabolism chr10 55581621 56424022 |CDHR15|DFNB23|USH1F| NP_001136235 0 FALSE 2
79026 AHNAK AHNAK nucleoprotein 11q12.2 14684 347 103390 NP_001611;NP_076965;XP_005274297;XP_005274298;XP_005274299;XP_005274300;XP_005274301;XP_005274302;XP_005274303;XP_006718749;XP_006718750;XP_006718751 NM_001620;NM_024060;XM_005274240;XM_005274241;XM_005274242;XM_005274243;XM_005274244;XM_005274245;XM_005274246;XM_006718686;XM_006718687;XM_006718688 ENSP00000367263 Q09666 TRUE can 0 0 0 Metazoans 2 Development chr11 62284219 62303570 |AHNAKRS| NP_001611 0 FALSE 1 33 9638 0.1440 1
79037 PVRIG poliovirus receptor related immunoglobulin domain containing 7q22.1 - 32190 - NP_076975;XP_006716188 NM_024070;XM_006716125 ENSP00000311153;ENSP00000316675 Q6DKI7 TRUE can 0 0 1 Mammals 0 -1 chr7 99817534 99818871 |C7orf15| NP_076975 1 FALSE 1
79058 ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1 17q25.3 6947 13825 606236 NP_001238817;NP_076988 NM_001251888;NM_024083;NR_045351 ENSP00000302176 Q9BZE9 TRUE cgc 1 0 0 Eukaryotes 0 -1 chr17 79935523 79974988 |ASPCR1|ASPL|RCC17|TUG|UBXD9|UBXN9| NP_001238817 0 FALSE 1 18 5178 0.1630
79145 CHCHD7 coiled-coil-helix-coiled-coil-helix domain containing 7 8q12.1 13048 28314 611238 NP_001011667;NP_001011668;NP_001011669;NP_001011670;NP_001011671;NP_077276 NM_001011667;NM_001011668;NM_001011669;NM_001011670;NM_001011671;NM_024300;XR_428340 ENSP00000306425 Q9BUK0 TRUE cgc 1 0 0 Eukaryotes 3 -1 chr8 57125410 57129991 |COX23| NP_001011668 0 FALSE 1
79161 TMEM243 transmembrane protein 243, mitochondrial 7q21.12 12911 21707 - NP_077291;XP_005250642;XP_005250643;XP_005250644;XP_005250645;XP_005250646 NM_024315;XM_005250585;XM_005250586;XM_005250587;XM_005250588;XM_005250589 ENSP00000257637 Q9BU79 TRUE can 0 0 0 Metazoans 0 -1 chr7 86827134 86848819 |C7orf23|MM-TRAG| XP_005250642 0 FALSE 1
79190 IRX6 iroquois homeobox 6 16q12.2 - 14675 606196 NP_077311;XP_005256194;XP_005256195 NM_024335;XM_005256137;XM_005256138 ENSP00000290552 P78412 TRUE can 0 0 0 Eukaryotes 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr16 55359004 55363222 |IRX-3|IRX7|IRXB3| NP_077311 0 FALSE 1
79544 OR4K1 olfactory receptor, family 4, subfamily K, member 1 14q11.2 14975 14726 - NP_001004063 NM_001004063 ENSP00000285600 Q8NGD4 TRUE can 0 0 5 Mammals 0 Cell response to stimuli,Signal transduction chr14 20403826 20404758 |OR14-19| NP_001004063 5 TRUE 1 1
79577 CDC73 cell division cycle 73 1q25 9581 16783 607393 NP_078805;XP_006711600 NM_024529;XM_006711537 ENSP00000356405 Q6P1J9 TRUE cgc 0 1 0 Eukaryotes 1 Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism chr1 193091331 193219002 |C1orf28|FIHP|HPTJT|HRPT1|HRPT2|HYX| NP_078805 0 FALSE 1 74 31218 0.0620 5
79633 FAT4 FAT atypical cadherin 4 4q28.1 7637 23109 612411 NP_078858;XP_005263267;XP_006714367 NM_024582;XM_005263210;XM_006714304 ENSP00000377862 Q6V0I7 TRUE can 0 0 0 Last Universal Common Ancestor 1 Cell motility and interactions chr4 126237567 126412920 |CDHF14|CDHR11|FAT-J|FATJ|HKLLS2|NBLA00548|VMLDS2| XP_005263267 0 FALSE 3 6 708 0.1330
79718 TBL1XR1 transducin (beta)-like 1 X-linked receptor 1 3q26.32 15476 29529 608628 NP_078941;XP_005247828;XP_005247829;XP_005247832;XP_005247833;XP_006713808;XP_006713809 NM_024665;XM_005247771;XM_005247772;XM_005247775;XM_005247776;XM_006713745;XM_006713746 ENSP00000405574 Q9BZK7 TRUE cgc 0 0 2 Last Universal Common Ancestor 3 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr3 176744158 176816329 |C21|DC42|IRA1|TBLR1| XP_005247828 2 FALSE 2 34 4404 0.2190 9
79728 PALB2 partner and localizer of BRCA2 16p12.2 7966 26144 610355 NP_078951 NM_024675 ENSP00000261584 Q86YC2 TRUE cgc 0 1 0 Vertebrates 0 -1 chr16 23614783 23652478 |FANCN|PNCA3| NP_078951 0 FALSE 2 35 8441 0.0570 2
79755 ZNF750 zinc finger protein 750 17q25.3 8588 25843 610226 NP_078978 NM_024702 ENSP00000269394 Q32MQ0 TRUE can 0 0 0 Vertebrates 0 -1 chr17 80788021 80790330 |ZFP750| NP_078978 0 FALSE 1 1 0 0.0000
79776 ZFHX4 zinc finger homeobox 4 8q21.11 9503 30939 606940 NP_078997 NM_024721 ENSP00000430497 Q86UP3 TRUE can 0 0 0 Metazoans 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr8 77616324 77776798 |ZFH4|ZHF4| NP_078997 0 FALSE 3 2 0 1.0000
79791 FBXO31 F-box protein 31 16q24.2 10954 16510 609102 NP_001269612;NP_079011 NM_001282683;NM_024735 ENSP00000310841 Q5XUX0 TRUE can 0 0 0 Metazoans 2 -1 chr16 87364897 87417350 |FBX14|FBXO14|Fbx31|MRT45|pp2386| NP_079011 0 FALSE 1 9 156 0.3060 1
79799 UGT2A3 UDP glucuronosyltransferase 2 family, polypeptide A3 4q13.2 8646 28528 - NP_079019;XP_006714368;XP_006725063 NM_024743;NR_024010;XM_006714305;XM_006725000 ENSP00000251566;ENSP00000447309 Q6UWM9 TRUE can 0 0 3 Last Universal Common Ancestor 0 -1 chr4 69795534 69817478 |NA| NP_079019 3 FALSE 1
79822 ARHGAP28 Rho GTPase activating protein 28 18p11.31 10961 25509 610592 NP_001010000;XP_005258201;XP_005258202;XP_005258203 NM_001010000;NM_030672;XM_005258144;XM_005258145;XM_005258146 ENSP00000313506 B4DXL2 TRUE can 0 0 0 Eukaryotes 6 Signal transduction chr18 6729821 6912150 |NA| XP_005258201 0 FALSE 1
79839 CCDC102B coiled-coil domain containing 102B 18q22.1 8038 26295 - NP_001087198;NP_079057;XP_005266821;XP_005266822;XP_005266825;XP_006722605;XP_006722606;XP_006722607;XP_006722608;XP_006722609 NM_001093729;NM_024781;XM_005266764;XM_005266765;XM_005266768;XM_006722542;XM_006722543;XM_006722544;XM_006722545;XM_006722546;XR_430083;XR_430084;XR_430085 ENSP00000316237;ENSP00000368401;ENSP00000383178 Q68D86 TRUE can 0 0 0 Metazoans 3 -1 chr18 66504001 66721371 |ACY1L|C18orf14|HsT1731| NP_001087198 0 FALSE 1 51 9353 0.0580
79883 PODNL1 podocan-like 1 19p13.12 8027 26275 - NP_001139726;NP_001139727;NP_079101;XP_006722964;XP_006722965;XP_006722966;XP_006722967 NM_001146254;NM_001146255;NM_024825;XM_006722901;XM_006722902;XM_006722903;XM_006722904 ENSP00000345175 Q6PEZ8 TRUE can 0 0 0 Eukaryotes 1 -1 chr19 14043521 14048819 |SLRR5B| NP_079101 0 FALSE 1
79892 MCMBP minichromosome maintenance complex binding protein 10q26.11 7624 25782 610909 NP_001243307;NP_001243308;NP_079110;XP_005270214 NM_001256378;NM_001256379;NM_024834;XM_005270157 ENSP00000353098 Q9BTE3 TRUE can 0 0 0 Eukaryotes 3 -1 chr10 121590989 121632096 |C10orf119|MCM-BP| NP_079110 0 FALSE 1 23 5771 0.1980
79937 CNTNAP3 contactin associated protein-like 3 9p13.1 10842 13834 610517 NP_387504;XP_005251642;XP_005251643;XP_006716934;XP_006716935;XP_006716936;XP_006716937;XP_006716938;XP_006716939 NM_033655;XM_005251585;XM_005251586;XM_006716871;XM_006716872;XM_006716873;XM_006716874;XM_006716875;XM_006716876;XR_428430 ENSP00000366787 Q9BZ76 TRUE can 0 0 2 Eukaryotes 3 Signal transduction chr9 39073890 39288061 |CASPR3|CNTNAP3A| NP_387504 2 FALSE 1 1 0 0.0000
79983 POF1B premature ovarian failure, 1B Xq21.2 6679 13711 300603 NP_079197;XP_005262259;XP_005262260 NM_024921;XM_005262202;XM_005262203 ENSP00000262753 Q8WVV4 TRUE can 0 0 0 Vertebrates 0 -1 chrX 84537188 84634459 |POF2B| XP_005262259 0 FALSE 1 3 16 0.3330
80036 TRPM3 transient receptor potential cation channel, subfamily M, member 3 9q21.12 10605 17992 608961 NP_001007471;NP_001007472;NP_066003;NP_079247;NP_996827;NP_996828;NP_996829;NP_996830;NP_996831;XP_005252275 NM_001007470;NM_001007471;NM_020952;NM_024971;NM_206944;NM_206945;NM_206946;NM_206947;NM_206948;XM_005252218 ENSP00000366314 Q9HCF6 TRUE can 0 0 0 Eukaryotes 0 Cellular processes chr9 73150872 74061751 |GON-2|LTRPC3|MLSN2| XP_005252275 0 FALSE 1
80059 LRRTM4 leucine rich repeat transmembrane neuronal 4 2p12 11288 19411 610870 NP_001128217;NP_001269853;NP_001269857;NP_079269 NM_001134745;NM_001282924;NM_001282928;NM_024993 ENSP00000386357 Q86VH4 TRUE can 0 0 0 Last Universal Common Ancestor 0 -1 chr2 77745444 77746991 |NA| NP_001128217 0 FALSE 1
80070 ADAMTS20 ADAM metallopeptidase with thrombospondin type 1 motif, 20 12q12 - 17178 611681 NP_079279 NM_025003;NM_175851 ENSP00000374071 P59510 TRUE can 0 0 0 Eukaryotes 0 Cellular metabolism chr12 43748015 43945724 |ADAM-TS20|ADAMTS-20|GON-1| NP_079279 0 FALSE 1
80204 FBXO11 F-box protein 11 2p16.3 6985 13590 607871 NP_001177203;NP_079409;XP_005264629;XP_005264630;XP_005264631 NM_001190274;NM_012167;NM_018693;NM_025133;XM_005264572;XM_005264573;XM_005264574 ENSP00000384823 Q86XK2 TRUE cgc 0 1 0 Last Universal Common Ancestor 6 Cellular metabolism,Cellular processes chr2 48035260 48132859 |FBX11|UBR6|VIT1| XP_005264629 0 FALSE 1 20 4098 0.2110 2
80230 RUFY1 RUN and FYVE domain containing 1 5q35.3 15282 19760 610327 NP_001035541;NP_001035542;NP_079434;XP_005266050;XP_006714984;XP_006714985 NM_001040451;NM_001040452;NM_025158;XM_005265993;XM_006714921;XM_006714922;XR_245276;XR_245277 ENSP00000325594 Q96T51 TRUE can 0 0 0 Metazoans 0 Cellular processes chr5 178977571 179036517 |RABIP4|ZFYVE12| NP_079434 0 FALSE 1 33 6492 0.0450
80243 PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2 8q13.2 - 22950 612139 NP_079146;NP_079446 NM_024870;NM_025170 ENSP00000288368 Q70Z35 TRUE can 0 0 0 Last Universal Common Ancestor 1 Signal transduction chr8 68864630 69143610 |6230420N16Rik|DEP.2|DEPDC2|P-REX2|PPP1R129| NP_079146 0 FALSE 2 4 98 0.1670
80304 C2orf44 chromosome 2 open reading frame 44 2p23.3 7972 26157 - NP_001135791;NP_079479 NM_001142319;NM_025203 ENSP00000295148 Q9H6R7 TRUE cgc 1 0 0 Metazoans 2 -1 chr2 24253806 24262364 |NA| NP_079479 0 FALSE 1 18 929 0.0200
80309 SPHKAP SPHK1 interactor, AKAP domain containing 2q36 18052 30619 611646 NP_001136116;NP_085126;XP_005246924;XP_005246925;XP_005246927;XP_006712840;XP_006712841 NM_001142644;NM_030623;XM_005246867;XM_005246868;XM_005246870;XM_006712777;XM_006712778 ENSP00000375909 Q2M3C7 TRUE can 0 0 0 Vertebrates 0 -1 chr2 228846436 228996802 |NA| XP_005246924 0 FALSE 1 2 23 0.0000
80312 TET1 tet methylcytosine dioxygenase 1 10q21 9694 29484 607790 NP_085128 NM_030625 ENSP00000362748 Q8NFU7 TRUE cgc 1 0 0 Metazoans 4 -1 chr10 70332096 70451568 |CXXC6|LCX|bA119F7.1| NP_085128 0 FALSE 2 1 0 0.0000
80314 EPC1 enhancer of polycomb homolog 1 (Drosophila) 10p11 9941 19876 610999 NP_001258933;NP_001258948;NP_001269320;NP_079485;XP_006717573 NM_001272004;NM_001272019;NM_001282391;NM_025209;NR_104159;NR_104160;XM_006717510;XR_428649 ENSP00000263062 Q9H2F5 TRUE can 0 0 0 Eukaryotes 7 Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr10 32557994 32635843 |Epl1| NP_079485 0 FALSE 1 16 709 0.2170 15
80380 PDCD1LG2 programmed cell death 1 ligand 2 9p24.2 16147 18731 605723 NP_079515;XP_005251657;XP_005251658;XP_005251659 NM_025239;XM_005251600;XM_005251601;XM_005251602 ENSP00000380855 Q9BQ51 TRUE cgc 1 0 0 Mammals 0 -1 chr9 5522547 5563214 |B7DC|Btdc|CD273|PD-L2|PDCD1L2|PDL2|bA574F11.2| XP_005251657 0 FALSE 1 1 0 0.0000 3
80731 THSD7B thrombospondin, type I, domain containing 7B 2q22.1 - 29348 - NP_001073896;XP_005263859 NM_001080427;XM_005263802 ENSP00000272643 C9JKN6 TRUE can 0 0 0 Eukaryotes 0 -1 chr2 137639749 138434172 |NA| XP_005263859 0 FALSE 2 1 0 0.0000
80737 VWA7 von Willebrand factor A domain containing 7 6p21.33 12880 13939 609693 NP_079534;XP_005249484;XP_005249485;XP_005249486;XP_005272961;XP_005272962;XP_005272963;XP_005274951;XP_005274952;XP_005274953;XP_005275116;XP_005275117;XP_005275118;XP_005275373;XP_005275374;XP_005275375;XP_005275677;XP_005275678;XP_005275679;XP_006715283;XP_006725113;XP_006725592;XP_006725811;XP_006726007;XP_006726196 NM_025258;XM_005249427;XM_005249428;XM_005249429;XM_005272904;XM_005272905;XM_005272906;XM_005274894;XM_005274895;XM_005274896;XM_005275059;XM_005275060;XM_005275061;XM_005275316;XM_005275317;XM_005275318;XM_005275620;XM_005275621;XM_005275622;XM_006715220;XM_006725050;XM_006725529;XM_006725748;XM_006725944;XM_006726133 ENSP00000364840;ENSP00000390732;ENSP00000406943;ENSP00000411804;ENSP00000411910;ENSP00000413704 Q9Y334 TRUE can 0 0 0 Eukaryotes 1 Cell response to stimuli chr6 31733374 31744556 |C6orf27|G7c|NG37| XP_005249484 0 FALSE 1 1 0 0.0000
81309 OR4C15 olfactory receptor, family 4, subfamily C, member 15 11q11 14963 15171 - NP_001001920 NM_001001920 ENSP00000324958 Q8NGM1 TRUE can 0 0 0 Mammals 0 Cell response to stimuli,Signal transduction chr11 55321783 55322892 |OR11-127|OR11-134| NP_001001920 0 TRUE 2 1
81501 DCSTAMP dendrocyte expressed seven transmembrane protein 8q23 7295 18549 605933 NP_001244246;NP_110415;XP_005251132 NM_001257317;NM_030788;XM_005251075 ENSP00000297581 Q9H295 TRUE can 0 0 0 Vertebrates 2 Development chr8 105360781 105368423 |FIND|TM7SF4|hDC-STAMP| NP_110415 0 FALSE 1 2 0 1.0000
81558 FAM117A family with sequence similarity 117, member A 17q21.33 17432 24179 - NP_110429 NM_030802 ENSP00000240364 Q9C073 TRUE can 0 0 0 Metazoans 0 -1 chr17 47788620 47841449 |NA| NP_110429 0 FALSE 1 2 0 0.0000
81608 FIP1L1 factor interacting with PAPOLA and CPSF1 4q12 9646 19124 607686 NP_001128409;NP_001128410;NP_112179;XP_005265825;XP_005265826;XP_005265827;XP_005265828;XP_005265829;XP_005265830;XP_005265831;XP_005265832;XP_005265833;XP_005265834;XP_005265835;XP_005265836;XP_005265837;XP_005265838;XP_005265839 NM_001134937;NM_001134938;NM_030917;XM_005265768;XM_005265769;XM_005265770;XM_005265771;XM_005265772;XM_005265773;XM_005265774;XM_005265775;XM_005265776;XM_005265777;XM_005265778;XM_005265779;XM_005265780;XM_005265781;XM_005265782 ENSP00000336752 Q6UN15 TRUE cgc 1 0 0 Eukaryotes 1 DNA/RNA metabolism and transcription,Regulation of transcription chr4 54244006 54325613 |Rhe|hFip1| XP_005265825 0 FALSE 1 31 10410 0.1310 1
81614 NIPA2 non imprinted in Prader-Willi/Angelman syndrome 2 15q11.2 16290 17044 608146 NP_001008860;NP_001008892;NP_001008894;NP_001171817;NP_001171818;NP_112184;XP_005272603;XP_005272604;XP_005272605;XP_005272606;XP_005272607;XP_005272609;XP_005272610;XP_006720427;XP_006720428;XP_006720429;XP_006720430;XP_006720431 NM_001008860;NM_001008892;NM_001008894;NM_001184888;NM_001184889;NM_030922;XM_005272546;XM_005272547;XM_005272548;XM_005272549;XM_005272550;XM_005272552;XM_005272553;XM_006720364;XM_006720365;XM_006720366;XM_006720367;XM_006720368 ENSP00000337618 Q8N8Q9 TRUE can 0 0 1 Eukaryotes 0 -1 chr15 23006224 23021336 |NA| NP_001008860 1 FALSE 1
81704 DOCK8 dedicator of cytokinesis 8 9p24.3 10920 19191 611432 NP_001177387;NP_001180465;NP_982272 NM_001190458;NM_001193536;NM_203447 ENSP00000408464 Q8NF50 TRUE can 0 0 0 Eukaryotes 0 -1 chr9 214977 464216 |HEL-205|MRD2|ZIR8| NP_982272 0 FALSE 1 34 8314 0.0640 1
81792 ADAMTS12 ADAM metallopeptidase with thrombospondin type 1 motif, 12 5q35 5862 14605 606184 NP_112217 NM_030955 ENSP00000422554 P58397 TRUE can 0 0 0 Eukaryotes 2 Cellular metabolism chr5 33527296 33891961 |PRO4389| NP_112217 0 FALSE 1 4 238 0.0000
81831 NETO2 neuropilin (NRP) and tolloid (TLL)-like 2 16q11 9721 14644 607974 NP_001188406;NP_060562;XP_006721352;XP_006721353;XP_006721354;XP_006721355 NM_001201477;NM_018092;XM_006721289;XM_006721290;XM_006721291;XM_006721292 ENSP00000455169 Q8NC67 TRUE can 0 0 1 Metazoans 6 -1 chr16 47117135 47165937 |BTCL2|NEOT2| NP_060562 1 FALSE 1 1 0 0.0000
81839 VANGL1 VANGL planar cell polarity protein 1 1p13.1 18279 15512 610132 NP_001165882;NP_001165883;NP_620409;XP_006710998;XP_006710999 NM_001172411;NM_001172412;NM_138959;XM_006710935;XM_006710936 ENSP00000310800 Q8TAA9 TRUE can 0 0 0 Metazoans 7 -1 chr1 116194035 116233997 |KITENIN|STB2|STBM2| NP_001165883 0 FALSE 1 13 7013 0.0380
83417 FCRL4 Fc receptor-like 4 1q21 16168 18507 605876 NP_112572 NM_031282;XR_241099 ENSP00000271532 Q96PJ5 TRUE cgc 1 0 0 Vertebrates 1 -1 chr1 157545317 157559252 |CD307d|FCRH4|IGFP2|IRTA1| NP_112572 0 FALSE 1 2 264 0.0000
83737 ITCH itchy E3 ubiquitin protein ligase 20q11.22 - 13890 606409 NP_001244066;NP_001244067;NP_113671;XP_005260627;XP_006723944;XP_006723945 NM_001257137;NM_001257138;NM_031483;XM_005260570;XM_006723881;XM_006723882;XR_244153;XR_430315 ENSP00000363998 Q96J02 TRUE can 0 0 0 Eukaryotes 1 Cell cycle,Cell motility and interactions,Cellular metabolism,Cellular processes,Immune system response,Other,Regulation of intracellular processes and metabolism chr20 32981618 33095596 |ADMFD|AIF4|AIP4|NAPP1|dJ468O1.1| NP_001244066 0 FALSE 1 134 82368 0.0640 27
83741 TFAP2D transcription factor AP-2 delta (activating enhancer binding protein 2 delta) 6p12.1 11627 15581 610161 NP_758438 NM_172238 ENSP00000008391 Q7Z6R9 TRUE can 0 0 0 - 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr6 50682829 50740574 |TFAP2BL1| NP_758438 0 FALSE 1
83872 HMCN1 hemicentin 1 1q25.3-q31.1 6509 19194 608548 NP_114141 NM_031935 ENSP00000271588 Q96RW7 TRUE can 0 0 0 Eukaryotes 1 Cell response to stimuli,Cellular metabolism,Cellular processes chr1 185703912 186159007 |ARMD1|FBLN6|FIBL-6|FIBL6| NP_114141 0 FALSE 3 2 1 0.0000
83990 BRIP1 BRCA1 interacting protein C-terminal helicase 1 17q22.2 - 20473 605882 NP_114432 NM_032043 ENSP00000259008 Q9BX63 TRUE cgc 0 1 0 Last Universal Common Ancestor 3 Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction chr17 59760660 59938900 |FANCJ| NP_114432 0 FALSE 2 12 225 0.3480 1
83999 KREMEN1 kringle containing transmembrane protein 1 22q12.1 11182 17550 609898 NP_001034659;NP_114434 NM_001039570;NM_032045;NM_153379 ENSP00000331242 Q96MU8 TRUE can 0 0 0 Eukaryotes 1 Signal transduction chr22 29469119 29538088 |KREMEN|KRM1| NP_114434 0 FALSE 1 1 0 0.0000
84059 GPR98 G protein-coupled receptor 98 5q13 9111 17416 602851 NP_115495 NM_032119;NR_003149 ENSP00000384582 Q8WXG9 TRUE can 0 0 0 Last Universal Common Ancestor 0 Cell response to stimuli,Development,Regulation of intracellular processes and metabolism,Signal transduction chr5 89910651 90459714 |FEB4|MASS1|USH2B|USH2C|VLGR1|VLGR1b| NP_115495 0 FALSE 1
84072 HORMAD1 HORMA domain containing 1 1q21.3 11396 25245 609824 NP_001186758;NP_115508;XP_006711632;XP_006711633;XP_006711634 NM_001199829;NM_032132;XM_006711569;XM_006711570;XM_006711571 ENSP00000355167 Q86X24 TRUE can 0 0 2 Eukaryotes 0 Cell cycle chr1 150671133 150689758 |CT46|NOHMA| NP_001186758 1 FALSE 1 2 13 0.0000
84075 FSCB fibrous sheath CABYR binding protein 14q21.2 12638 20494 611779 NP_115511 NM_032135 ENSP00000344579 Q5H9T9 TRUE can 0 0 0 Mammals 2 -1 chr14 44973716 44976190 |C14orf155| NP_115511 0 FALSE 1
84076 TKTL2 transketolase-like 2 4q32.2 13159 25313 - NP_115512 NM_032136 ENSP00000280605 Q9H0I9 TRUE can 0 0 0 Last Universal Common Ancestor 1 -1 chr4 164393009 164394886 |NA| NP_115512 0 FALSE 1 1 0 0.0000
84106 PRAM1 PML-RARA regulated adaptor molecule 1 19p13.2 5926 30091 606466 NP_115528;XP_005272559 NM_032152;XM_005272502 ENSP00000408342 Q96QH2 TRUE can 0 0 0 Vertebrates 0 Cellular metabolism,Cellular processes,Immune system response,Regulation of intracellular processes and metabolism,Signal transduction chr19 8555076 8564664 |PML-RAR|PRAM-1| XP_005272559 0 FALSE 1 26 5455 0.1380
84107 ZIC4 Zic family member 4 3q24 12340 20393 608948 NP_001161850;NP_001161851;NP_001230185;NP_115529 NM_001168378;NM_001168379;NM_001243256;NM_032153;NR_033118;NR_033119;NR_040762 ENSP00000435509 Q8N9L1 TRUE can 0 0 0 Last Universal Common Ancestor 0 -1 chr3 147108720 147121885 |NA| NP_001161850 0 FALSE 1 1 0 0.0000
84125 LRRIQ1 leucine-rich repeats and IQ motif containing 1 12q21.31 9952 25708 - NP_001073379;XP_005269238;XP_005269240;XP_006719695;XP_006719696;XP_006719697;XP_006719698 NM_001079910;NM_032165;XM_005269181;XM_005269183;XM_006719632;XM_006719633;XM_006719634;XM_006719635 ENSP00000376910 Q96JM4 TRUE can 0 0 0 Eukaryotes 0 -1 chr12 85431955 85638716 |NA| NP_001073379 0 FALSE 1 1 0 0.0000
84128 WDR75 WD repeat domain 75 2q32.2 7775 25725 - NP_115544 NM_032168 ENSP00000314193 Q8IWA0 TRUE can 0 0 0 Eukaryotes 4 -1 chr2 190306219 190340140 |NET16|UTP17| NP_115544 0 FALSE 1 6 51 0.2670
84133 ZNRF3 zinc and ring finger 3 22q12.1 - 18126 612062 NP_001193927;NP_115549;XP_005261830;XP_005261831;XP_006724396 NM_001206998;NM_032173;XM_005261773;XM_005261774;XM_006724333 ENSP00000443824 Q9ULT6 TRUE can 0 0 0 Eukaryotes 4 -1 chr22 29279755 29446938 |BK747E2.3|RNF203| NP_001193927 0 FALSE 2 7 1105 0.0950 4
84159 ARID5B AT rich interactive domain 5B (MRF1-like) 10q21.2 - 17362 608538 NP_001231567;NP_115575 NM_001244638;NM_032199 ENSP00000279873 Q14865 TRUE can 0 0 0 Eukaryotes 5 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr10 63661912 63852786 |DESRT|MRF-2|MRF2| NP_115575 0 FALSE 1 6 126 0.4670 1
84181 CHD6 chromodomain helicase DNA binding protein 6 20q12 13049 19057 - NP_115597;XP_005260630;XP_005260631;XP_005260632;XP_005260633;XP_006723946 NM_032221;XM_005260573;XM_005260574;XM_005260575;XM_005260576;XM_006723883 ENSP00000240874;ENSP00000262450;ENSP00000327716;ENSP00000362330 Q8TD26 TRUE can 0 0 0 Last Universal Common Ancestor 1 Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription chr20 40033236 40162212 |CHD-6|RIGB| NP_115597 0 FALSE 1 10 221 0.0440
84189 SLITRK6 SLIT and NTRK-like family, member 6 13q31.1 15403 23503 609681 NP_115605 NM_032229 ENSP00000383143 Q9H5Y7 TRUE can 0 0 0 Metazoans 0 -1 chr13 86368121 86370643 |DFNMYP| NP_115605 0 FALSE 2 1 0 0.0000
84219 WDR24 WD repeat domain 24 16p13.3 15665 20852 - NP_115635 NM_032259 ENSP00000293883 Q96S15 TRUE can 0 0 0 Eukaryotes 0 -1 chr16 734737 739640 |C16orf21|JFP7| NP_115635 0 FALSE 1 3 64 0.0000
84231 TRAF7 TNF receptor-associated factor 7, E3 ubiquitin protein ligase 16p13.3 6977 20456 606692 NP_115647;XP_005255684 NM_032271;NM_206835;XM_005255627 ENSP00000318944 Q6Q0C0 TRUE cgc 1 0 0 Eukaryotes 0 Cell cycle,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction chr16 2213922 2226388 |RFWD1|RNF119| NP_115647 0 FALSE 1 9 187 0.1390 1
84295 PHF6 PHD finger protein 6 Xq26.3 2330 18145 300414 NP_001015877;NP_115711;NP_115834 NM_001015877;NM_032335;NM_032458 ENSP00000329097 Q8IWS0 TRUE cgc 0 1 0 Eukaryotes 6 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chrX 133511648 133559357 |BFLS|BORJ|CENP-31| NP_001015877 0 FALSE 1 34 1425 0.1750
84376 HOOK3 hook microtubule-tethering protein 3 8p11.21 9699 23576 607825 NP_115786 NM_032410 ENSP00000292432;ENSP00000305699 Q86VS8 TRUE cgc 1 0 0 Eukaryotes 1 Cellular processes chr8 42752275 42873638 |NA| NP_115786 0 FALSE 1 10 2527 0.2890 1
84433 CARD11 caspase recruitment domain family, member 11 7p22 6234 16393 607210 NP_115791;XP_006715857;XP_006715858;XP_006715859 NM_032415;XM_006715794;XM_006715795;XM_006715796 ENSP00000380150 Q9BXL7 TRUE cgc 1 0 0 Vertebrates 1 Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Immune system response,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction chr7 2946275 2987422 |BENTA|BIMP3|CARMA1|IMD11|PPBL| NP_115791 0 FALSE 2 24 1831 0.2070 15
84435 GPR123 G protein-coupled receptor 123 10q26 17058 13838 612302 NP_001077378;XP_005252752 NM_001083909;NM_032422;XM_005252695 ENSP00000376384 Q86SQ6 TRUE can 0 0 0 Eukaryotes 3 Signal transduction chr10 134884433 134943012 |NA| XP_005252752 0 FALSE 1
84441 MAML2 mastermind-like 2 (Drosophila) 11q21 9608 16259 607537 NP_115803 NM_032427 ENSP00000412394 Q8IZL2 TRUE cgc 1 0 0 Vertebrates 1 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction chr11 95712115 96075059 |MAM-3|MAM3|MLL-MAML2| NP_115803 0 FALSE 2 9 8495 0.2780 6
84444 DOT1L DOT1-like histone H3K79 methyltransferase 19p13.3 10455 24948 607375 NP_115871;XP_005259716;XP_005259717;XP_006722986 NM_032482;XM_005259659;XM_005259660;XM_006722923 ENSP00000381657 Q8TEK3 TRUE can 0 0 0 Eukaryotes 0 DNA/RNA metabolism and transcription chr19 2164184 2228343 |DOT1|KMT4| XP_005259716 0 FALSE 1 26 1180 0.1260
84446 BRSK1 BR serine/threonine kinase 1 19q13.4 12533 18994 609235 NP_115806;XP_005259384 NM_032430;XM_005259327;XR_430213 ENSP00000310649 Q8TDC3 TRUE can 0 0 0 Last Universal Common Ancestor 0 Cell cycle,Cell response to stimuli,Cellular metabolism,Cellular processes,Development,Signal transduction chr19 55795811 55823433 |hSAD1| NP_115806 0 FALSE 1 8 2306 0.0000
84448 ABLIM2 actin binding LIM protein family, member 2 4p16.1 - 19195 612544 NP_001123555;NP_001123556;NP_001123557;NP_001123558;NP_001123559;NP_001123560;NP_001273617;NP_115808;XP_005248071;XP_005248072;XP_005248073;XP_005248074;XP_005248075;XP_005248076;XP_005248077;XP_005248078;XP_005248079;XP_005248080;XP_005248081;XP_005248082;XP_005248083;XP_005248084;XP_005248085;XP_005248086;XP_005248087;XP_005248088;XP_006713984;XP_006713985;XP_006713986;XP_006713987;XP_006713988;XP_006713989;XP_006713990 NM_001130083;NM_001130084;NM_001130085;NM_001130086;NM_001130087;NM_001130088;NM_001286688;NM_032432;XM_005248014;XM_005248015;XM_005248016;XM_005248017;XM_005248018;XM_005248019;XM_005248020;XM_005248021;XM_005248022;XM_005248023;XM_005248024;XM_005248025;XM_005248026;XM_005248027;XM_005248028;XM_005248029;XM_005248030;XM_005248031;XM_006713921;XM_006713922;XM_006713923;XM_006713924;XM_006713925;XM_006713926;XM_006713927 ENSP00000393511 Q6H8Q1 TRUE can 0 0 0 Eukaryotes 0 Cellular processes chr4 7968720 8108368 |NA| XP_005248071 0 FALSE 1 4 31 0.3330
84451 KIAA1804 mixed lineage kinase 4 1q42 10087 - 614793 NP_115811 NM_032435 ENSP00000355583 Q5TCX8 TRUE can 0 0 0 Eukaryotes 6 Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism,Signal transduction chr1 233463775 233518454 |KIAA1804|MLK4|dJ862P8.3| NP_115811 0 FALSE 2 2 8 0.0000
84461 NEURL4 neuralized E3 ubiquitin protein ligase 4 17p13 13894 34410 615865 NP_001005408;NP_115818 NM_001005408;NM_032442 ENSP00000370104;ENSP00000382390;ENSP00000468772 Q96JN8 TRUE can 0 0 0 Metazoans 0 -1 chr17 7219445 7232631 |NA| NP_115818 0 FALSE 1 25 2600 0.1330
84539 MCHR2 melanin-concentrating hormone receptor 2 6q16 - 20867 606111 NP_001035269;NP_115892 NM_001040179;NM_032503 ENSP00000281806 Q969V1 TRUE can 0 0 0 Vertebrates 1 Signal transduction chr6 100368819 100404023 |GPR145|GPRv17|MCH-2R|MCH-R2|MCH2R|MCHR-2|SLT| NP_001035269 0 FALSE 1 1 0 0.0000 5
84570 COL25A1 collagen, type XXV, alpha 1 4q25 9886 18603 610004 NP_001243003;NP_115907;NP_942014 NM_001256074;NM_032518;NM_198721;NR_045756 ENSP00000382083 Q9BXS0 TRUE can 0 0 0 Eukaryotes 0 Cellular processes chr4 109740408 110223175 |CLAC-P|CLACP| NP_942014 0 FALSE 1 3 3433 0.3330 1
84612 PARD6B par-6 family cell polarity regulator beta 20q13.13 18703 16245 608975 NP_115910 NM_032521 ENSP00000360672 Q9BYG5 TRUE can 0 0 0 Metazoans 6 Cell cycle,Cell motility and interactions,Cellular processes,Development chr20 49348324 49367022 |PAR6B| NP_115910 0 FALSE 1 28 14616 0.1900 6
84620 ST6GAL2 ST6 beta-galactosamide alpha-2,6-sialyltranferase 2 2q11.2-q12.1 12237 10861 608472 NP_001135823;NP_001135824;NP_115917;XP_006712864;XP_006712865 NM_001142351;NM_001142352;NM_032528;XM_006712801;XM_006712802 ENSP00000355273 Q96JF0 TRUE can 0 0 0 Eukaryotes 0 Cellular metabolism,Cellular processes chr2 107423137 107460433 |SIAT2|ST6GalII| NP_001135823 0 FALSE 1
84627 ZNF469 zinc finger protein 469 16q24 - 23216 612078 NP_001120936 NM_001127464 ENSP00000402343 NA TRUE can 0 0 0 Eukaryotes 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr16 88493879 88505737 |NA| NP_001120936 0 FALSE 1
84636 GPR174 G protein-coupled receptor 174 Xq21.1 6512 30245 300903 NP_115942 NM_032553 ENSP00000276077 Q9BXC1 TRUE can 0 0 0 Vertebrates 0 Signal transduction chrX 78426505 78427503 |GPCR17|LYPSR3| NP_115942 0 FALSE 1
84643 KIF2B kinesin family member 2B 17q22 10053 29443 615142 NP_115948 NM_032559 ENSP00000268919 Q8N4N8 TRUE can 0 0 0 Eukaryotes 0 Cell cycle,Cellular processes chr17 51900395 51902413 |NA| NP_115948 0 FALSE 1 1 0 0.0000 8
84674 CARD6 caspase recruitment domain family, member 6 5p13.1 9871 16394 609986 NP_115976 NM_032587 ENSP00000254691 Q9BX69 TRUE can 0 0 0 Mammals 0 Cell cycle chr5 40841485 40854545 |CINCIN1| NP_115976 0 FALSE 1 5 31 0.2000
84678 KDM2B lysine (K)-specific demethylase 2B 12q24.31 12362 13610 609078 NP_001005366;NP_115979;XP_005254011;XP_005254012;XP_005254013;XP_005254018 NM_001005366;NM_032590;XM_005253954;XM_005253955;XM_005253956;XM_005253961 ENSP00000366271 Q8NHM5 TRUE can 0 0 0 Eukaryotes 2 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr12 121868094 122018816 |CXXC2|FBXL10|Fbl10|JHDM1B|PCCX2| NP_115979 0 FALSE 1 16 620 0.2000 1
84700 MYO18B myosin XVIIIB 22q12.1 9529 18150 607295 NP_115997;XP_005261843;XP_005261844;XP_005261845;XP_006724403;XP_006724404 NM_032608;XM_005261786;XM_005261787;XM_005261788;XM_006724340;XM_006724341 ENSP00000334563 Q8IUG5 TRUE can 0 0 0 Eukaryotes 0 -1 chr22 26157060 26423641 |NA| XP_005261843 0 FALSE 1 5 322 0.1000
84767 TRIM51 tripartite motif-containing 51 11q11 10282 19023 - NP_116070 NM_032681 ENSP00000395086 Q9BSJ1 TRUE can 0 0 10 Eukaryotes 0 -1 chr11 55652905 55659105 |SPRYD5|TRIM51A| NP_116070 10 FALSE 1 3 26 0.0000
84808 PERM1 PPARGC1 and ESRR induced regulator, muscle 1 1p36.33 - 28208 615921 - NM_032722;NR_027693 - Q5SV97 TRUE can 0 0 -1 - 0 -1 - 0 0 |C1orf170| - -1 FALSE 1
84962 AJUBA ajuba LIM protein 14q11.2 16426 20250 609066 NP_001276026;NP_116265;NP_932352 NM_001289097;NM_032876;NM_198086 ENSP00000262713 Q96IF1 TRUE can 0 0 0 Eukaryotes 3 -1 chr14 23442655 23451475 |JUB| NP_116265 0 FALSE 2 24 2635 0.0940 1
85378 TUBGCP6 tubulin, gamma complex associated protein 6 22q13.31-q13.33 15589 18127 610053 NP_065194 NM_001008658;NM_020461;XR_244458;XR_430483 ENSP00000248846 Q96RT7 TRUE can 0 0 0 Eukaryotes 1 Cellular processes chr22 50656168 50682888 |GCP-6|GCP6|MCCRP|MCPHCR| NP_065194 0 FALSE 1 7 205 0.4760 5
85414 SLC45A3 solute carrier family 45, member 3 1q32.1 16312 8642 605097 NP_149093;XP_005245613;XP_005245614;XP_005245615;XP_005245616;XP_005245617 NM_033102;XM_005245556;XM_005245557;XM_005245558;XM_005245559;XM_005245560 ENSP00000356113 Q96JT2 TRUE cgc 1 0 0 Eukaryotes 2 -1 chr1 205628365 205633784 |IPCA-2|IPCA-6|IPCA-8|IPCA6|PCANAP2|PCANAP6|PCANAP8|PRST| NP_149093 0 FALSE 1
85441 HELZ2 helicase with zinc finger 2, transcriptional coactivator 20q13.33 11459 30021 611265 NP_001032412;NP_208384 NM_001037335;NM_033405 ENSP00000417401 Q9BYK8 TRUE can 0 0 0 Last Universal Common Ancestor 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr20 62190602 62203738 |PDIP-1|PRIC285| NP_001032412 0 FALSE 1 5 83 0.0000 2
85442 KNDC1 kinase non-catalytic C-lobe domain (KIND) containing 1 10q26.3 13931 29374 - NP_689856 NM_152643 ENSP00000304437 Q76NI1 TRUE can 0 0 0 Metazoans 0 Signal transduction chr10 134973972 135038391 |C10orf23|RASGEF2|bB439H18.3| NP_689856 0 FALSE 1 2 4 0.0000
85452 CFAP74 cilia and flagella associated protein 74 1p36.33 - 29368 - NP_001073953;XP_005244868;XP_006711060;XP_006711061 NM_001080484;XM_005244811;XM_006710997;XM_006710998 ENSP00000417061 NA TRUE can 0 0 0 Metazoans 0 -1 chr1 1853729 1922395 |C1orf222|KIAA1751| XP_005244868 0 FALSE 1
89795 NAV3 neuron navigator 3 12q14.3 10114 15998 611629 NP_001019554;NP_055718;XP_005269272;XP_006719738;XP_006719739;XP_006719740 NM_001024383;NM_014903;XM_005269215;XM_006719675;XM_006719676;XM_006719677 ENSP00000446132 Q8IVL0 TRUE can 0 0 0 Metazoans 0 -1 chr12 78225242 78604294 |POMFIL1|STEERIN3|unc53H3| NP_001019554 0 FALSE 2 4 42 0.3330
89857 KLHL6 kelch-like family member 6 3q27.3 10035 18653 614214 NP_569713 NM_130446 ENSP00000343273 Q8WZ60 TRUE can 0 0 0 Eukaryotes 0 -1 chr3 183209718 183273441 |NA| NP_569713 0 FALSE 1 5 130 0.3000
90167 FRMD7 FERM domain containing 7 Xq26.2 6624 8079 300628 NP_919253;XP_005262550 NM_194277;XM_005262493 ENSP00000298542 Q6ZUT3 TRUE can 0 0 0 Eukaryotes 2 -1 chrX 131211903 131261872 |NYS|NYS1|XIPAN| NP_919253 0 FALSE 1
90417 KNSTRN kinetochore-localized astrin/SPAG5 binding protein 15q15.1 12669 30767 614718 NP_001136233;NP_001136234;NP_150628;XP_005254813 NM_001142761;NM_001142762;NM_033286;XM_005254756 ENSP00000249776 Q9Y448 TRUE can 0 0 0 Vertebrates 0 -1 chr15 40675037 40685795 |C15orf23|SKAP|TRAF4AF1| NP_150628 0 FALSE 1 11 3615 0.0360
90993 CREB3L1 cAMP responsive element binding protein 3-like 1 11p11.2 16751 18856 - NP_443086;XP_006718443 NM_052854;XM_006718380 ENSP00000434939 Q96BA8 TRUE cgc 1 0 0 Opisthokonts 0 Cell response to stimuli,Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr11 46299663 46342080 |OASIS| NP_443086 0 FALSE 1 22 23643 0.0300
91010 FMNL3 formin-like 3 12q13.12 17007 23698 - NP_783863;NP_944489;XP_005269275;XP_005269276;XP_006719749 NM_175736;NM_198900;XM_005269218;XM_005269219;XM_006719686 ENSP00000257209;ENSP00000335655 Q8IVF7 TRUE can 0 0 0 Eukaryotes 3 Cellular processes chr12 50040448 50100963 |WBP-3|WBP3| XP_005269275 0 FALSE 1 5 450 0.4000 2
91156 IGFN1 immunoglobulin-like and fibronectin type III domain containing 1 1q32.1 - 24607 - NP_001158058;XP_005245637;XP_006711680;XP_006711681 NM_001164586;NM_178275;XM_005245580;XM_006711617;XM_006711618 ENSP00000334714 Q86VF2 TRUE can 0 0 0 Eukaryotes 3 -1 chr1 201163281 201196335 |EEF1A2BP1| NP_001158058 0 FALSE 1 2 66 0.0000
91523 PCED1B PC-esterase domain containing 1B 12q13.11 17513 28255 - NP_001268358;NP_612380;XP_005269281;XP_005269283;XP_005269285;XP_006719753;XP_006719754 NM_001281429;NM_138371;XM_005269224;XM_005269226;XM_005269228;XM_006719690;XM_006719691 ENSP00000396040 Q96HM7 TRUE can 0 0 0 Metazoans 3 -1 chr12 47628847 47630142 |FAM113B| NP_001268358 0 FALSE 1 1
91603 ZNF830 zinc finger protein 830 17q12 - 28291 - NP_443089 NM_052857 ENSP00000354518 Q96NB3 TRUE can 0 0 0 Eukaryotes 0 Cell cycle,Development chr17 33288586 33289701 |CCDC16|OMCG1| NP_443089 0 FALSE 1 14 293 0.1100
91661 ZNF765 zinc finger protein 765 19q13.42 14285 25092 - NP_001035275;XP_006723529;XP_006723530 NM_001040185;NM_138372;XM_006723466;XM_006723467;XR_430215 ENSP00000379689 Q7L2R6 TRUE can 0 0 -1 Eukaryotes 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription - 0 0 |NA| - -1 FALSE 1
91752 ZNF804A zinc finger protein 804A 2q32.1 12804 21711 612282 NP_919226 NM_194250 ENSP00000303252 Q7Z570 TRUE can 0 0 0 Vertebrates 1 -1 chr2 185463687 185803750 |C2orf10| NP_919226 0 FALSE 1 2 131 0.0000
92002 FAM58A family with sequence similarity 58, member A Xq28 6645 28434 300708 NP_001124469;NP_689487;XP_005277977;XP_005277978 NM_001130997;NM_152274;XM_005277920;XM_005277921 ENSP00000461135 Q8N1B3 TRUE can 0 0 4 Eukaryotes 0 -1 chr5 172189520 172190261 |NA| NP_689487 4 FALSE 1 1 0 0.0000
92017 SNX29 sorting nexin 29 16p13.13-p13.12 17437 30542 - NP_115543;XP_005255739;XP_005255740;XP_006721040;XP_006721041 NM_001009607;NM_001080530;NM_032167;XM_005255682;XM_005255683;XM_006720977;XM_006720978 ENSP00000268271 Q8TEQ0 TRUE cgc 1 0 0 Metazoans 1 -1 chr16 12077531 12662483 |A-388D4.1|RUNDC2A| XP_005255739 0 FALSE 1
92521 SPECC1 sperm antigen with calponin homology and coiled-coil domains 1 17p11.2 12301 30615 608793 NP_001028725;NP_001028726;NP_001028727;NP_001230367;NP_001230368;NP_690868;XP_005256916;XP_005256917;XP_006721655;XP_006721656;XP_006721657 NM_001033553;NM_001033554;NM_001033555;NM_001243438;NM_001243439;NM_152904;XM_005256859;XM_005256860;XM_006721592;XM_006721593;XM_006721594 ENSP00000261503 Q5M775 TRUE cgc 1 0 0 Metazoans 1 -1 chr17 19999965 20217375 |CYTSB|HCMOGT-1|HCMOGT1| NP_001028725 0 FALSE 1 7 353 0.0950
92552 ATXN3L ataxin 3-like Xp22.2 - - 300920 NP_001129467 NM_001135995 ENSP00000369996 Q9H3M9 TRUE can 0 0 0 Eukaryotes 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chrX 13336989 13338053 |MJDL| NP_001129467 0 FALSE 1 7 69 0.4290
92737 DNER delta/notch-like EGF repeat containing 2q36.3 9531 24456 607299 NP_620711;XP_005247007 NM_139072;XM_005246950 ENSP00000345229 Q8NFT8 TRUE can 0 0 0 Eukaryotes 0 Cell cycle,Cell motility and interactions,Cellular metabolism,Cellular processes,Development,Multicellular activities,Signal transduction chr2 230223259 230579139 |UNQ26|bet| NP_620711 0 FALSE 1 4 65 0.1670 1
92799 SHKBP1 SH3KBP1 binding protein 1 19q13.2 15338 19214 - NP_612401;XP_006723537;XP_006723538 NM_138392;XM_006723474;XM_006723475 ENSP00000291842 Q8TBC3 TRUE can 0 0 0 Eukaryotes 0 Cellular processes chr19 41082806 41097110 |Sb1| NP_612401 0 FALSE 1 15 1413 0.2000
92856 IMP4 IMP4, U3 small nucleolar ribonucleoprotein 2q21.1 10002 30856 612981 NP_219484;XP_005263901 NM_033416;XM_005263844 ENSP00000259239 Q96G21 TRUE can 0 0 0 Last Universal Common Ancestor 1 DNA/RNA metabolism and transcription,Regulation of transcription chr2 131100659 131104038 |BXDC4| NP_219484 0 FALSE 1 3 337 0.0000 1
93035 PKHD1L1 polycystic kidney and hepatic disease 1 (autosomal recessive)-like 1 8q23 9703 20313 607843 NP_803875 NM_177531 ENSP00000367655 Q86WI1 TRUE can 0 0 0 Last Universal Common Ancestor 1 -1 chr8 110374810 110539248 |PKHDL1| NP_803875 0 FALSE 1
93492 TPTE2 transmembrane phosphoinositide 3-phosphatase and tensin homolog 2 13q12.11 6003 17299 606791 NP_001135440;NP_001258779;NP_570141;NP_954863 NM_001141968;NM_001271850;NM_130785;NM_199254;NM_199255;NR_073485;NR_073486;NR_073487 ENSP00000372437 Q6XPS3 TRUE can 0 0 2 Last Universal Common Ancestor 1 -1 chr13 19997205 20067643 |TPIP| NP_954863 2 FALSE 1 3 125 0.0000
93669 C12orf9 - - - - - - - - NA TRUE cgc 1 0 -1 - 0 -1 - 0 0 |C12orf9| - -1 FALSE 1
94025 MUC16 mucin 16, cell surface associated 19p13.2 - 15582 606154 NP_078966;XP_006723004 NM_024690;XM_006722941 ENSP00000381008 Q8WXI7 TRUE can 0 0 0 Vertebrates 0 -1 chr19 9056228 9091814 |CA125| NP_078966 0 TRUE 2 4 487 0.1670
94234 FOXQ1 forkhead box Q1 6p25 - 20951 612788 NP_150285 NM_033260 ENSP00000296839 Q9C009 TRUE can 0 0 0 Eukaryotes 3 Cellular metabolism,DNA/RNA metabolism and transcription,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Regulation of transcription chr6 1312940 1314148 |HFH1| NP_150285 0 FALSE 1
113791 PIK3IP1 phosphoinositide-3-kinase interacting protein 1 22q12.2 17518 24942 - NP_001129383;NP_443112 NM_001135911;NM_052880 ENSP00000215912 Q96FE7 TRUE can 0 0 0 Vertebrates 1 -1 chr22 31679073 31688330 |hHGFL(S)| NP_443112 0 FALSE 1 1 0 0.0000
114134 SLC2A13 solute carrier family 2 (facilitated glucose transporter), member 13 12q12 15363 15956 611036 NP_443117;XP_005268673 NM_052885;XM_005268616 ENSP00000280871 Q96QE2 TRUE can 0 0 0 Last Universal Common Ancestor 1 Cellular processes chr12 40153831 40499610 |HMIT| NP_443117 0 FALSE 1
114548 NLRP3 NLR family, pyrin domain containing 3 1q44 5915 16400 606416 NP_001073289;NP_001120933;NP_001120934;NP_001230062;NP_004886;NP_899632;XP_005273093;XP_005273094;XP_005273095;XP_006711796 NM_001079821;NM_001127461;NM_001127462;NM_001243133;NM_004895;NM_183395;XM_005273036;XM_005273037;XM_005273038;XM_006711733 ENSP00000337383 Q96P20 TRUE can 0 0 0 Metazoans 1 Cell cycle,Cell response to stimuli,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Immune system response,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction chr1 247582097 247611803 |AGTAVPRL|AII|C1orf7|CIAS1|CLR1.1|FCAS|FCU|MWS|NALP3|PYPAF1| NP_001073289 0 FALSE 1 9 565 0.1390 2
114780 PKD1L2 polycystic kidney disease 1-like 2 16q23.2 6990 21715 607894 NP_001070248;NP_001265352;NP_001265354;NP_443124 NM_001076780;NM_001278423;NM_001278425;NM_052892;NM_182740 ENSP00000469432 Q7Z442 TRUE can 0 0 0 Metazoans 0 Cellular processes,Signal transduction chr16 81134731 81253975 |PC1L2| NP_443124 0 FALSE 1
114788 CSMD3 CUB and Sushi multiple domains 3 8q23.3 16329 19291 608399 NP_443132;NP_937756;NP_937757 NM_052900;NM_198123;NM_198124 ENSP00000297405 Q7Z407 TRUE can 0 0 0 Eukaryotes 0 -1 chr8 113237003 114449083 |NA| NP_937756 0 TRUE 9
114795 TMEM132B transmembrane protein 132B 12q24.31 17230 29397 - NP_001273148;NP_443139;XP_006719282;XP_006719283;XP_006719284 NM_001286219;NM_052907;XM_006719219;XM_006719220;XM_006719221 ENSP00000299308 Q14DG7 TRUE can 0 0 0 Metazoans 3 -1 chr12 125811170 126139253 |NA| NP_443139 0 FALSE 1
114805 GALNT13 polypeptide N-acetylgalactosaminyltransferase 13 2q24.1 16325 23242 608369 NP_443149;XP_005246324;XP_006712293 NM_052917;XM_005246267;XM_006712230 ENSP00000344260;ENSP00000376570 Q8IUC8 TRUE can 0 0 1 Eukaryotes 0 -1 chr2 154801011 155307060 |GalNAc-T13| NP_443149 1 FALSE 1 3 55 0.0000
114815 SORCS1 sortilin-related VPS10 domain containing receptor 1 10q23-q25 12098 16697 606283 NP_001013049;NP_001193498;NP_001193499;NP_001193500;NP_001193501;NP_443150;XP_005269532 NM_001013031;NM_001206569;NM_001206570;NM_001206571;NM_001206572;NM_052918;XM_005269475 ENSP00000345964 Q8WY21 TRUE can 0 0 0 Eukaryotes 0 Signal transduction chr10 108336982 108924284 |hSorCS| NP_001013049 0 FALSE 1 2 10 0.0000
114907 FBXO32 F-box protein 32 8q24.13 5966 16731 606604 NP_001229392;NP_478136;NP_680482 NM_001242463;NM_058229;NM_148177 ENSP00000428205 Q969P5 TRUE can 0 0 0 Metazoans 0 -1 chr8 124515616 124553254 |Fbx32|MAFbx| NP_478136 0 FALSE 1 15 604 0.0860 1
115350 FCRL1 Fc receptor-like 1 1q21-q22 7350 18509 606508 NP_001152869;NP_001152870;NP_443170;XP_005244923;XP_005244924;XP_005244926 NM_001159397;NM_001159398;NM_052938;XM_005244866;XM_005244867;XM_005244869 ENSP00000356936;ENSP00000357158 Q96LA6 TRUE can 0 0 0 Mammals 0 -1 chr1 157765892 157773902 |CD307a|FCRH1|IFGP1|IRTA5| NP_443170 0 FALSE 1
116028 RMI2 RecQ mediated genome instability 2 16p13.13 14497 28349 612426 NP_689521 NM_152308 ENSP00000310356 Q96E14 TRUE cgc 1 0 0 Metazoans 0 -1 chr16 11439329 11444644 |BLAP18|C16orf75| NP_689521 0 FALSE 1 7 169 0.3330
116285 ACSM1 acyl-CoA synthetase medium-chain family member 1 16p12.3 12551 18049 614357 NP_443188;XP_005255141;XP_005255143;XP_006721079;XP_006721080;XP_006721081 NM_052956;XM_005255084;XM_005255086;XM_006721016;XM_006721017;XM_006721018;XR_243258;XR_429672 ENSP00000301956 Q08AH1 TRUE can 0 0 0 Last Universal Common Ancestor 1 Cellular metabolism chr16 20634811 20702510 |BUCS1|MACS1| NP_443188 0 FALSE 1
116511 MAS1L MAS1 proto-oncogene like, G protein-coupled receptor 6p22.1 6251 13961 607235 NP_443199 NM_052967 ENSP00000366331;ENSP00000373041;ENSP00000373139;ENSP00000392071;ENSP00000399042;ENSP00000405030;ENSP00000405164;ENSP00000410649 P35410 TRUE can 0 0 0 Mammals 3 Signal transduction chr6 29454546 29455679 |MAS-L|dJ994E9.2| NP_443199 0 FALSE 1
116931 MED12L mediator complex subunit 12-like 3q25.1 10278 16050 611318 NP_443728;XP_006713550 NM_053002;XM_006713487 ENSP00000417235 Q86YW9 TRUE can 0 0 0 Eukaryotes 1 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr3 150804714 151150589 |NOPAR|TNRC11L|TRALP|TRALPUSH| NP_443728 0 FALSE 1 2 7 0.0000
117154 DACH2 dachshund family transcription factor 2 Xq21.3 6481 16814 300608 NP_001132986;NP_001132987;NP_444511;XP_005262125 NM_001139514;NM_001139515;NM_053281;XM_005262068 ENSP00000362217 Q96NX9 TRUE can 0 0 0 Metazoans 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chrX 85403625 86087155 |NA| NP_444511 0 FALSE 1 2 4 0.0000
118491 CFAP70 cilia and flagella associated protein 70 10q22.2 - 30726 - NP_660153;XP_005269545;XP_005269546;XP_006717667;XP_006717668;XP_006717669;XP_006717670;XP_006717671;XP_006717672;XP_006717673;XP_006717674;XP_006717675;XP_006717676;XP_006717677 NM_145170;XM_005269488;XM_005269489;XM_006717604;XM_006717605;XM_006717606;XM_006717607;XM_006717608;XM_006717609;XM_006717610;XM_006717611;XM_006717612;XM_006717613;XM_006717614;XR_428694;XR_428695 ENSP00000310829 Q5T0N1 TRUE can 0 0 0 Eukaryotes 1 -1 chr10 75013736 75114554 |TTC18| NP_660153 0 FALSE 1
118788 PIK3AP1 phosphoinositide-3-kinase adaptor protein 1 10q24.1 6401 30034 607942 NP_689522;XP_005269555;XP_005269556 NM_152309;XM_005269498;XM_005269499 ENSP00000339826 Q6ZUJ8 TRUE can 0 0 0 Metazoans 0 -1 chr10 98355337 98469741 |NA| NP_689522 0 FALSE 1 6 51 0.4670 1
119548 PNLIPRP3 pancreatic lipase-related protein 3 10q25.3 18542 23492 - NP_001011709 NM_001011709 ENSP00000358232 Q17RR3 TRUE can 0 0 0 Mammals 1 Cellular metabolism chr10 118187525 118236662 |NA| NP_001011709 0 FALSE 1
119559 SFXN4 sideroflexin 4 10q26.11 18046 16088 615564 NP_998814;XP_005269582;XP_005269583;XP_005269584;XP_006717688 NM_178867;NM_213649;NR_110305;XM_005269525;XM_005269526;XM_005269527;XM_006717625 ENSP00000347924 Q6P4A7 TRUE can 0 0 0 Eukaryotes 0 Cellular processes chr10 120900757 120925159 |BCRM1|COXPD18| NP_998814 0 FALSE 1 5 156 0.2000
119749 OR4C46 olfactory receptor, family 4, subfamily C, member 46 11p11.12 14964 31271 614273 NP_001004703 NM_001004703 ENSP00000329056 A6NHA9 TRUE can 0 0 12 Mammals 0 Cell response to stimuli,Signal transduction chr11 51515282 51516208 |NA| NP_001004703 12 TRUE 1 1
120114 FAT3 FAT atypical cadherin 3 11q14.3 - 23112 612483 NP_001008781;XP_006718827 NM_001008781;XM_006718764 ENSP00000298047 Q8TDW7 TRUE can 0 0 0 Eukaryotes 6 Cell motility and interactions chr11 92085279 92624276 |CDHF15|CDHR10| NP_001008781 0 FALSE 5 2 14 0.0000
120892 LRRK2 leucine-rich repeat kinase 2 12q12 - 18618 609007 NP_940980;XP_005268686 NM_198578;XM_005268629 ENSP00000298910 Q5S007 TRUE can 0 0 0 Last Universal Common Ancestor 2 Cell cycle,Cellular metabolism,Cellular processes,Development,Regulation of intracellular processes and metabolism,Signal transduction chr12 40618934 40761564 |AURA17|DARDARIN|PARK8|RIPK7|ROCO2| NP_940980 0 FALSE 1 245 278302 0.0270 1
121227 LRIG3 leucine-rich repeats and immunoglobulin-like domains 3 12q14.1 8317 30991 608870 NP_001129523;NP_700356 NM_001136051;NM_153377 ENSP00000326759 Q6UXM1 TRUE cgc 1 0 0 Last Universal Common Ancestor 3 -1 chr12 59266357 59314016 |NA| NP_700356 0 FALSE 1 1 0 0.0000
121256 TMEM132D transmembrane protein 132D 12q24.33 13906 29411 611257 NP_597705 NM_133448 ENSP00000408581 Q14C87 TRUE can 0 0 0 Metazoans 0 -1 chr12 129558423 130387884 |MOLT|PPP1R153| NP_597705 0 FALSE 1 1 0 0.0000
121364 OR10A7 olfactory receptor, family 10, subfamily A, member 7 12q13.2 14883 15329 - NP_001005280 NM_001005280 ENSP00000326718 Q8NGE5 TRUE can 0 0 0 Vertebrates 0 Cell response to stimuli,Signal transduction chr12 55614809 55615756 |OR12-6| NP_001005280 0 TRUE 1 1
121601 ANO4 anoctamin 4 12q23.1 15527 23837 610111 NP_001273544;NP_001273545;NP_849148;XP_006719303 NM_001286615;NM_001286616;NM_178826;XM_006719240 ENSP00000376705;ENSP00000471210 Q32M45 TRUE can 0 0 0 Eukaryotes 0 -1 chr12 101295564 101520845 |TMEM16D| NP_001273544 0 FALSE 1
122740 OR4K14 olfactory receptor, family 4, subfamily K, member 14 14q11.2 14977 15352 - NP_001004712 NM_001004712 ENSP00000305011 Q8NGD5 TRUE can 0 0 0 - 0 Cell response to stimuli,Signal transduction chr14 20482423 20483352 |OR14-18|OR14-22| NP_001004712 0 TRUE 1 1
122742 OR4L1 olfactory receptor, family 4, subfamily L, member 1 14q11.2 14982 15356 - NP_001004717 NM_001004717 ENSP00000319217 Q8NH43 TRUE can 0 0 0 Mammals 0 Cell response to stimuli,Signal transduction chr14 20528204 20529139 |OR14-28|OR4L2P| NP_001004717 0 TRUE 1 1
124540 MSI2 musashi RNA-binding protein 2 17q22 7438 18585 607897 NP_620412;NP_733839;XP_005257071;XP_005257072;XP_005257073;XP_005257075;XP_006721744 NM_138962;NM_170721;XM_005257014;XM_005257015;XM_005257016;XM_005257018;XM_006721681 ENSP00000284073 Q96DH6 TRUE cgc 1 0 0 Eukaryotes 1 -1 chr17 55334104 55752487 |MSI2H| XP_005257071 0 FALSE 1 13 1080 0.2180
124583 CANT1 calcium activated nucleotidase 1 17q25.3 13003 19721 613165 NP_001153244;NP_001153245;NP_620148;XP_005257077;XP_005257078;XP_005257079;XP_006721745;XP_006721746 NM_001159772;NM_001159773;NM_138793;XM_005257020;XM_005257021;XM_005257022;XM_006721682;XM_006721683;XR_243633 ENSP00000307674 Q8WVQ1 TRUE cgc 1 0 0 Eukaryotes 4 Regulation of intracellular processes and metabolism,Signal transduction chr17 76989635 76993704 |DBQD|SCAN-1|SCAN1|SHAPY| NP_001153244 0 FALSE 1 2 5 0.0000
125963 OR1M1 olfactory receptor, family 1, subfamily M, member 1 19p13.2 17689 8220 - NP_001004456 NM_001004456 ENSP00000401966 Q8NGA1 TRUE can 0 0 0 - 0 Cell response to stimuli,Signal transduction chr19 9203921 9204859 |NA| NP_001004456 0 TRUE 1 1
126206 NLRP5 NLR family, pyrin domain containing 5 19q13.43 10111 21269 609658 NP_703148 NM_153447 ENSP00000375063 P59047 TRUE can 0 0 0 Mammals 0 -1 chr19 56515083 56572891 |CLR19.8|MATER|NALP5|PAN11|PYPAF8| NP_703148 0 FALSE 1
126410 CYP4F22 cytochrome P450, family 4, subfamily F, polypeptide 22 19p13.12 8256 26820 611495 NP_775754 NM_173483 ENSP00000269703 Q6NT55 TRUE can 0 0 0 Last Universal Common Ancestor 1 -1 chr19 15636148 15662279 |ARCI5|INLNE|LI3| NP_775754 0 FALSE 1
126567 C2CD4C C2 calcium-dependent domain containing 4C 19p13.3 - 29417 610336 NP_001129735;XP_006722712 NM_001136263;XM_006722649 ENSP00000328677 Q8TF44 TRUE can 0 0 0 Metazoans 0 -1 chr19 407099 408361 |FAM148C|KIAA1957|NLF3| NP_001129735 0 FALSE 1
127255 LRRIQ3 leucine-rich repeats and IQ motif containing 3 1p31.1 14485 28318 - NP_001099129;XP_005270508;XP_005270509;XP_005270510;XP_005270511;XP_006710415;XP_006710416 NM_001105659;NM_145258;XM_005270451;XM_005270452;XM_005270453;XM_005270454;XM_006710352;XM_006710353 ENSP00000346414 A6PVS8 TRUE can 0 0 0 Eukaryotes 0 -1 chr1 74492500 74649368 |LRRC44| NP_001099129 0 FALSE 1 2 11 0.0000
127294 MYOM3 myomesin 3 1p36.11 8200 26679 - NP_689585 NM_152372 ENSP00000363557 Q5VTT5 TRUE can 0 0 0 Vertebrates 0 -1 chr1 24383857 24435126 |NA| NP_689585 0 FALSE 1 2 2 0.0000
127602 DNAH14 dynein, axonemal, heavy chain 14 1q42.12 - 2945 603341 NP_001138626;NP_001364;NP_659426;XP_006711798 NM_001145154;NM_001373;NM_144989;XM_006711735 ENSP00000383737 Q0VDD8 TRUE can 0 0 0 Metazoans 0 -1 chr1 225140405 225586968 |C1orf67|Dnahc14|HL-18|HL18| NP_001364 0 FALSE 1 1 0 0.0000
128611 ZNF831 zinc finger protein 831 20q13.32 - 16167 - NP_848552;XP_005260329;XP_005260330;XP_005260331;XP_005260332;XP_006723761 NM_178457;XM_005260272;XM_005260273;XM_005260274;XM_005260275;XM_006723698 ENSP00000360069 Q5JPB2 TRUE can 0 0 0 Eukaryotes 0 -1 chr20 57766075 57829795 |C20orf174|dJ492J12.1| NP_848552 0 FALSE 1
128674 PROKR2 prokineticin receptor 2 20p12.3 8453 15836 607123 NP_658986;XP_005260720 NM_144773;XM_005260663 ENSP00000217270 Q8NFJ6 TRUE can 0 0 1 Metazoans 1 Signal transduction chr20 5282689 5295015 |GPR73L1|GPR73b|GPRg2|HH3|KAL3|dJ680N4.3| NP_658986 1 FALSE 1 3
129446 XIRP2 xin actin-binding repeat containing 2 2q24.3 10267 14303 609778 NP_001073278;NP_001186072;NP_001186073;NP_001186074;NP_689594;XP_006712319 NM_001079810;NM_001199143;NM_001199144;NM_001199145;NM_152381;XM_006712256 ENSP00000295237 A4UGR9 TRUE can 0 0 0 Vertebrates 1 Cellular processes chr2 167759993 168110633 |CMYA3| NP_689594 0 FALSE 1 7 278 0.0950
129684 CNTNAP5 contactin associated protein-like 5 2q14.3 16732 18748 610519 NP_570129;XP_006712321 NM_130773;NM_138996;XM_006712258 ENSP00000399013 Q8WYK1 TRUE can 0 0 0 Eukaryotes 0 Signal transduction chr2 124783228 125671862 |caspr5| NP_570129 0 TRUE 1
130507 UBR3 ubiquitin protein ligase E3 component n-recognin 3 (putative) 2q31.1 15887 30467 613831 NP_742067;XP_005246356;XP_005246357;XP_006712331;XP_006712332;XP_006712333;XP_006712334 NM_172070;XM_005246299;XM_005246300;XM_006712268;XM_006712269;XM_006712270;XM_006712271 ENSP00000396068 Q6ZT12 TRUE can 0 0 0 Eukaryotes 2 Cell response to stimuli,Cellular metabolism,Multicellular activities chr2 170684018 170938350 |ZNF650| XP_005246356 0 FALSE 1 4 6 0.1670
132243 H1FOO H1 histone family, member O, oocyte-specific 3q22.1 13621 18463 - NP_722575;XP_005247180 NM_153833;XM_005247123 ENSP00000319799 Q8IZA3 TRUE can 0 0 1 Metazoans 0 Cell cycle,DNA/RNA metabolism and transcription chr3 129262062 129270180 |osH1| NP_722575 1 FALSE 1
132884 EVC2 Ellis van Creveld syndrome 2 4p16.2-p16.1 6269 19747 607261 NP_001159608;NP_667338;XP_006713922;XP_006713923 NM_001166136;NM_147127;XM_006713859;XM_006713860 ENSP00000342144 Q86UK5 TRUE can 0 0 0 Vertebrates 0 -1 chr4 5564578 5710240 |LBN| NP_667338 0 FALSE 1 2 31 0.0000 2
133060 OTOP1 otopetrin 1 4p16.3 7421 19656 607806 NP_819056 NM_177998 ENSP00000296358 Q7RTM1 TRUE can 0 0 1 Vertebrates 0 Development chr4 4190533 4228591 |NA| NP_819056 1 FALSE 1
133558 MROH2B maestro heat-like repeat family member 2B 5p13.1 8808 26857 - NP_775760;XP_006714502 NM_173489;XM_006714439 ENSP00000382476 Q7Z745 TRUE can 0 0 0 Eukaryotes 0 -1 chr5 40998157 41069855 |HEATR7B2| NP_775760 0 FALSE 1 1 0 0.0000
133584 EGFLAM EGF-like, fibronectin type III and laminin G domains 5p13.2-p13.1 13433 26810 - NP_001192230;NP_689616;NP_877950;NP_877953;XP_006714503 NM_001205301;NM_152403;NM_182798;NM_182799;NM_182801;XM_006714440 ENSP00000346964 Q63HQ2 TRUE can 0 0 0 Eukaryotes 1 -1 chr5 38258857 38464085 |AGRINL|AGRNL|PIKA| NP_001192230 0 FALSE 1 3 99 0.3330
137209 ZNF572 zinc finger protein 572 8q24.13 15851 26758 - NP_689625 NM_152412 ENSP00000319305 Q7Z3I7 TRUE can 0 0 0 Eukaryotes 1 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr8 125988589 125990097 |NA| NP_689625 0 FALSE 1 25 4648 0.0900
137964 AGPAT6 1-acylglycerol-3-phosphate O-acyltransferase 6 8p11.21 12175 20880 608143 NP_848934;XP_005273460 NM_178819;XM_005273403 ENSP00000380184 Q86UL3 TRUE can 0 0 1 Last Universal Common Ancestor 2 Cell cycle,Cellular metabolism,Development,Multicellular activities chr8 41456659 41478517 |1-AGPAT 6|LPAAT-zeta|LPAATZ|TSARG7| NP_848934 1 FALSE 1 4 1915 0.0000
137970 UNC5D unc-5 homolog D (C. elegans) 8p12 11661 18634 - NP_543148;XP_006716351 NM_080872;XM_006716288 ENSP00000385143 Q6UXZ4 TRUE can 0 0 0 Metazoans 3 Cell cycle,Signal transduction chr8 35093303 35648078 |PRO34692|Unc5h4| NP_543148 0 FALSE 1
138009 DCAF4L2 DDB1 and CUL4 associated factor 4-like 2 8q21.3 8187 26657 - NP_689631 NM_152418 ENSP00000316496 Q8NA75 TRUE can 0 0 1 Eukaryotes 1 -1 chr8 88885015 88886199 |WDR21C| NP_689631 1 FALSE 1 1 0 0.0000
139081 MAGEC3 melanoma antigen family C, 3 Xq27.2 6629 23798 300469 NP_619647;NP_803251;XP_005262423 NM_138702;NM_177456;XM_005262366 ENSP00000298296 Q8TD91 TRUE can 0 0 0 Eukaryotes 1 -1 chrX 140926102 140985615 |CT7.2|MAGE-C3|MAGEC4| NP_619647 0 FALSE 1 2 9 0.0000
139135 PASD1 PAS domain containing 1 Xq28 6613 20686 - NP_775764 NM_173493 ENSP00000359382 Q8IV76 TRUE can 0 0 0 Mammals 0 Signal transduction chrX 150773117 150844612 |CT63|OXTES1| NP_775764 0 FALSE 1 1 0 0.0000
139285 AMER1 APC membrane recruitment protein 1 Xq11.2 6565 26837 300647 NP_689637;XP_005262298 NM_152424;XM_005262241 ENSP00000329117 Q5JTC6 TRUE cgc 0 1 0 Vertebrates 1 -1 chrX 63409762 63413166 |FAM123B|OSCS|WTX| NP_689637 0 FALSE 2 10 2656 0.4000 11
139378 GPR112 G protein-coupled receptor 112 Xq26.3 6578 18992 - NP_722576;XP_005262424 NM_153834;XM_005262367 ENSP00000359686 Q8IZF6 TRUE can 0 0 0 Eukaryotes 1 Signal transduction chrX 135390937 135496485 |PGR17|RP1-299I16| NP_722576 0 FALSE 1 1 0 0.0000
139628 FOXR2 forkhead box R2 Xp11.21 - 30469 - NP_940853 NM_198451 ENSP00000427329 Q6PJQ5 TRUE can 0 0 0 Eukaryotes 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chrX 55650145 55651077 |FOXN6| NP_940853 0 FALSE 1 2 18 0.0000
140831 ZSWIM3 zinc finger, SWIM-type containing 3 20q13.12 15903 16157 - NP_542790;XP_006723772 NM_080752;NR_037628;XM_006723709 ENSP00000255152 Q96MP5 TRUE can 0 0 0 Eukaryotes 2 -1 chr20 44486465 44507285 |C20orf164|PPP1R174| NP_542790 0 FALSE 1 1 0 0.0000
142685 ASB15 ankyrin repeat and SOCS box containing 15 7q31.31 10669 19767 - NP_563616;XP_005250201;XP_005250202;XP_005250203;XP_005250204;XP_005250205;XP_005250206;XP_006715916 NM_080928;XM_005250144;XM_005250145;XM_005250146;XM_005250147;XM_005250148;XM_005250149;XM_006715853 ENSP00000275699 Q8WXK1 TRUE can 0 0 0 Last Universal Common Ancestor 0 Signal transduction chr7 123254557 123277032 |NA| NP_563616 0 FALSE 1 19 366 0.0410
143187 VTI1A vesicle transport through interaction with t-SNAREs 1A 10q25.2 18290 17792 614316 NP_660207;XP_005269600;XP_005269601;XP_005269602;XP_005269603;XP_005269604;XP_005269605;XP_006717699;XP_006717700 NM_145206;XM_005269543;XM_005269544;XM_005269545;XM_005269546;XM_005269547;XM_005269548;XM_006717636;XM_006717637 ENSP00000376792 Q96AJ9 TRUE cgc 1 0 0 Eukaryotes 0 Cellular processes chr10 114207132 114575139 |MVti1|VTI1RP2|Vti1-rp2| XP_005269600 0 FALSE 1 9 134 0.3330 6
144535 CFAP54 cilia and flagella associated 54 12q23.1 - 26456 - XP_006710027;XP_006719787;XP_006726609 XM_006709964;XM_006719724;XM_006726546 ENSP00000431759 NA TRUE can 0 0 -1 Eukaryotes 0 -1 - 0 0 |C12orf55| - -1 FALSE 1
145264 SERPINA12 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12 14q32.13 18038 18359 - NP_776249;XP_005267408 NM_173850;XM_005267351 ENSP00000342109 Q8IW75 TRUE can 0 0 0 Last Universal Common Ancestor 0 -1 chr14 94953643 94964734 |OL-64| NP_776249 0 FALSE 1 1 0 0.0000
145581 LRFN5 leucine rich repeat and fibronectin type III domain containing 5 14q21.1 17445 20360 612811 NP_689660;XP_005267426 NM_152447;XM_005267369;XR_429293 ENSP00000298119 Q96NI6 TRUE can 0 0 0 Eukaryotes 0 -1 chr14 42355829 42368163 |C14orf146|FIGLER8|SALM5| NP_689660 0 FALSE 2
145788 C15orf65 chromosome 15 open reading frame 65 15q21.3 - 44654 - NP_001185713 NM_001198784 ENSP00000456337 H3BRN8 TRUE cgc 1 0 0 Metazoans 0 -1 chr15 55710421 55710765 |NA| NP_001185713 0 FALSE 1
146167 SLC38A8 solute carrier family 38, member 8 16q23.3 - 32434 615585 NP_001073911;XP_006721198 NM_001080442;XM_006721135 ENSP00000299709 A6NNN8 TRUE can 0 0 0 Last Universal Common Ancestor 0 Cellular processes chr16 84043392 84075762 |FVH2| NP_001073911 0 FALSE 1
146850 PIK3R6 phosphoinositide-3-kinase, regulatory subunit 6 17p13.1 - 27101 611462 NP_001010855 NM_001010855 - Q5UE93 TRUE can 0 0 0 - 0 -1 chr17 8706594 8743015 |C17orf38|HsT41028|p84 PIKAP|p87(PIKAP)|p87PIKAP| NP_001010855 0 FALSE 1 2 0 1.0000 1
146852 ODF4 outer dense fiber of sperm tails 4 17p13.1 17658 19056 610097 NP_694552;XP_005256533;XP_005256535 NM_153007;XM_005256476;XM_005256478 ENSP00000331086 Q2M2E3 TRUE can 0 0 0 Mammals 0 Development,Multicellular activities chr17 8243370 8249167 |CT136|OPPO1| NP_694552 0 FALSE 1 1 0 0.0000
147179 WIPF2 WAS/WASL interacting protein family, member 2 17q21.2 18304 30923 609692 NP_573571;XP_005257140;XP_005257141 NM_133264;XM_005257083;XM_005257084 ENSP00000320924 Q8TF74 TRUE can 0 0 0 Vertebrates 0 -1 chr17 38416784 38433435 |WICH|WIRE| NP_573571 0 FALSE 1 17 880 0.1400 6
147184 TMEM99 transmembrane protein 99 17q21.2 14478 28305 - NP_001182315;NP_001182316;NP_660317;XP_005257146 NM_001195386;NM_001195387;NM_145274;XM_005257089 - Q8N816 TRUE can 0 0 0 - 0 -1 chr17 38990769 38991542 |NA| NP_001182315 0 FALSE 1
147409 DSG4 desmoglein 4 18q12.1 6387 21307 607892 NP_001127925;NP_817123 NM_001134453;NM_177986 ENSP00000352785 Q86SJ6 TRUE can 0 0 0 Eukaryotes 0 Cell motility and interactions,Development,Multicellular activities chr18 28956875 28993555 |CDGF13|CDHF13|HYPT6|LAH| NP_001127925 0 FALSE 1
148345 C1orf127 chromosome 1 open reading frame 127 1p36.22 8780 26730 - NP_001164225;XP_006710440 NM_001170754;NM_173507;XM_006710377 ENSP00000366203 B7ZLG7 TRUE can 0 0 0 Mammals 0 -1 chr1 11007723 11036312 |NA| NP_001164225 0 FALSE 1
148823 GCSAML germinal center-associated, signaling and motility-like 1q44 14082 29583 - NP_001268763;NP_001268764;NP_001268765;NP_001268766;NP_001268767;NP_001268782;NP_660321 NM_001281834;NM_001281835;NM_001281836;NM_001281837;NM_001281838;NM_001281853;NM_145278 ENSP00000355444 Q5JQS6 TRUE can 0 0 0 Mammals 3 -1 chr1 247719707 247737681 |C1orf150| NP_001268782 0 FALSE 1
149371 EXOC8 exocyst complex component 8 1q42.2 9943 24659 615283 NP_787072 NM_175876 ENSP00000353564 Q8IYI6 TRUE can 0 0 0 Eukaryotes 1 Cellular processes chr1 231471317 231473491 |EXO84|Exo84p|SEC84| NP_787072 0 FALSE 1 34 13713 0.1110 4
150160 CCT8L2 chaperonin containing TCP1, subunit 8 (theta)-like 2 22q11.1 16708 15553 - NP_055221 NM_014406 ENSP00000353048 Q96SF2 TRUE can 0 0 1 Eukaryotes 0 Cellular metabolism,Cellular processes chr22 17071770 17073440 |CESK1| NP_055221 1 FALSE 1
150465 TTL tubulin tyrosine ligase 2q13 - 21586 608291 NP_714923;XP_005263656 NM_153712;XM_005263599 ENSP00000233336 Q8NG68 TRUE cgc 1 0 0 Eukaryotes 0 Cell cycle,Cellular metabolism,Cellular processes,Development,Regulation of intracellular processes and metabolism chr2 113239922 113286369 |NA| NP_714923 0 FALSE 1 2 180 0.0000
151056 PLB1 phospholipase B1 2p23.2 15141 30041 610179 NP_001164056;NP_694566 NM_001170585;NM_153021 ENSP00000330442 Q6P1J6 TRUE can 0 0 0 Opisthokonts 0 Cellular metabolism chr2 28718982 28865924 |PLB/LIP|hPLB| NP_694566 0 FALSE 1 4 69 0.0000
151742 PPM1L protein phosphatase, Mg2+/Mn2+ dependent, 1L 3q26.1 - 16381 611931 NP_640338;XP_006713570 NM_139245;XM_006713507 ENSP00000417659 Q5SGD2 TRUE can 0 0 0 Last Universal Common Ancestor 2 Cellular metabolism,Cellular processes chr3 160474097 160786942 |PP2C-epsilon|PPM1-LIKE| NP_640338 0 FALSE 1 1 0 0.0000 3
151888 BTLA B and T lymphocyte associated 3q13.2 6392 21087 607925 NP_001078826;NP_861445;XP_005247193 NM_001085357;NM_181780;XM_005247136 ENSP00000333919 Q7Z6A9 TRUE can 0 0 0 Vertebrates 1 -1 chr3 112184958 112218205 |BTLA1|CD272| NP_861445 0 FALSE 1 4 14593 0.1670 3
152007 GLIPR2 GLI pathogenesis-related 2 9p13.3 6187 18007 607141 NP_001273939;NP_001273940;NP_001273941;NP_001273942;NP_001273943;NP_071738 NM_001287010;NM_001287011;NM_001287012;NM_001287013;NM_001287014;NM_022343;NR_104637;NR_104638;NR_104639;NR_104640;NR_104641 ENSP00000367196 Q9H4G4 TRUE can 0 0 0 Last Universal Common Ancestor 1 -1 chr9 36136817 36162516 |C9orf19|GAPR-1|GAPR1| NP_001273942 0 FALSE 1 6 391 0.0670
152687 ZNF595 zinc finger protein 595 4p16.3 15868 27196 - NP_001272981;NP_001272982;NP_001272983;NP_872330 NM_001286052;NM_001286053;NM_001286054;NM_182524 ENSP00000437878 Q7Z3I0 TRUE can 0 0 2 Eukaryotes 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr4 85621 87314 |NA| NP_872330 2 FALSE 1 1 0 0.0000
153328 SLC25A48 solute carrier family 25, member 48 5q31.1 14098 30451 - NP_660325;XP_005271959;XP_005271960;XP_006714606;XP_006714607;XP_006714608;XP_006714609;XP_006714610;XP_006714611;XP_006714612;XP_006714613;XP_006714614;XP_006714615 NM_145282;XM_005271902;XM_005271903;XM_006714543;XM_006714544;XM_006714545;XM_006714546;XM_006714547;XM_006714548;XM_006714549;XM_006714550;XM_006714551;XM_006714552 ENSP00000413049 Q6ZT89 TRUE can 0 0 0 Eukaryotes 0 -1 chr5 135170537 135215787 |NA| XP_005271959 0 FALSE 1 4 29 0.0000
157724 SLC7A13 solute carrier family 7 (anionic amino acid transporter), member 13 8q21.3 15397 23092 - NP_620172;XP_005250861 NM_138817;XM_005250804 ENSP00000297524 Q8TCU3 TRUE can 0 0 0 Last Universal Common Ancestor 1 Cellular processes chr8 87226645 87242506 |AGT-1|XAT2| NP_620172 0 FALSE 1
157855 KCNU1 potassium channel, subfamily U, member 1 8p11.23 - 18867 615215 NP_001027006;XP_005273481 NM_001031836;XM_005273424 ENSP00000382770 A8MYU2 TRUE can 0 0 0 Eukaryotes 0 -1 chr8 36641929 36793435 |KCNMC1|KCa5|KCa5.1|Kcnma3|Slo3| NP_001027006 0 FALSE 1
158471 PRUNE2 prune homolog 2 (Drosophila) 9q21.2 12970 25209 610691 NP_056040;XP_005251802;XP_005251803;XP_005251805;XP_005251807;XP_005251808;XP_005251809;XP_005251810;XP_005251811;XP_006717045;XP_006717046;XP_006717047;XP_006717048;XP_006717049;XP_006717050 NM_015225;NM_138818;XM_005251745;XM_005251746;XM_005251748;XM_005251750;XM_005251751;XM_005251752;XM_005251753;XM_005251754;XM_006716982;XM_006716983;XM_006716984;XM_006716985;XM_006716986;XM_006716987;XR_242571;XR_428517;XR_428518 ENSP00000365908 Q8WUY3 TRUE can 0 0 0 Eukaryotes 6 Cell cycle,Development,Regulation of intracellular processes and metabolism chr9 79234258 79520879 |A214N16.3|BMCC1|BNIPXL|C9orf65|KIAA0367|bA214N16.3| XP_005251802 0 FALSE 1 12 739 0.3480
158584 FAAH2 fatty acid amide hydrolase 2 Xp11.21 6551 26440 300654 NP_777572;XP_005262039;XP_005262040;XP_005262041;XP_005262042;XP_005262043;XP_005262044 NM_174912;XM_005261982;XM_005261983;XM_005261984;XM_005261985;XM_005261986;XM_005261987 ENSP00000364035 Q6GMR7 TRUE can 0 0 0 Last Universal Common Ancestor 1 -1 chrX 57313259 57515362 |AMDD| NP_777572 0 FALSE 2 1 0 0.0000
160335 TMTC2 transmembrane and tetratricopeptide repeat containing 2 12q21.31 13230 25440 615856 NP_689801;XP_005268737 NM_152588;XM_005268680 ENSP00000322300 Q8N394 TRUE can 0 0 0 Last Universal Common Ancestor 6 -1 chr12 83081366 83526165 |IBDBP1| NP_689801 0 FALSE 1 1 0 0.0000
160418 TMTC3 transmembrane and tetratricopeptide repeat containing 3 12q21.32 10243 26899 - NP_861448;XP_005268739;XP_005268740;XP_005268741 NM_181783;XM_005268682;XM_005268683;XM_005268684 ENSP00000266712 Q6ZXV5 TRUE can 0 0 0 Last Universal Common Ancestor 13 -1 chr12 88542093 88589423 |NA| NP_861448 0 FALSE 1 1 0 0.0000
160762 CCDC63 coiled-coil domain containing 63 12q24.11 8765 26669 - NP_001273172;NP_001273173;NP_689804;XP_006719325;XP_006719326;XP_006719327 NM_001286243;NM_001286244;NM_152591;XM_006719262;XM_006719263;XM_006719264 ENSP00000312399 Q8NA47 TRUE can 0 0 0 Eukaryotes 0 -1 chr12 111291209 111345277 |ODA5| NP_689804 0 FALSE 1
161176 SYNE3 spectrin repeat containing, nuclear envelope family member 3 14q32.13 12652 19861 610861 NP_689805;XP_005267433;XP_005267434;XP_006720126;XP_006720127;XP_006720128;XP_006720129;XP_006720130 NM_152592;XM_005267376;XM_005267377;XM_006720063;XM_006720064;XM_006720065;XM_006720066;XM_006720067 ENSP00000334308 Q6ZMZ3 TRUE can 0 0 0 Eukaryotes 2 -1 chr14 95884166 95942158 |C14orf49|NET53|Nesp3| NP_689805 0 FALSE 1
162968 ZNF497 zinc finger protein 497 19q13.43 15806 23714 - NP_001193938;NP_940860 NM_001207009;NM_198458 ENSP00000311183 Q6ZNH5 TRUE can 0 0 0 Eukaryotes 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr19 58867508 58869001 |NA| NP_001193938 0 FALSE 1
165257 C1QL2 complement component 1, q subcomponent-like 2 2q14.2 12713 24181 614330 NP_872334;XP_006712409 NM_182528;XM_006712346 ENSP00000272520;ENSP00000438346 Q7Z5L3 TRUE can 0 0 0 Eukaryotes 0 Cellular processes chr2 119914381 119915845 |C1QTNF10|CTRP10| NP_872334 0 FALSE 1
166824 RASSF6 Ras association (RalGDS/AF-6) domain family member 6 4q13.3 15220 20796 612620 NP_001257320;NP_001257321;NP_803876;NP_958834 NM_001270391;NM_001270392;NM_177532;NM_201431 ENSP00000340578 Q6ZTQ3 TRUE can 0 0 0 Vertebrates 6 Signal transduction chr4 74441955 74486217 |NA| NP_958834 0 FALSE 1 5 110 0.3000
166968 MIER3 mesoderm induction early response 1, family member 3 5q11.2 8199 26678 - NP_689835;XP_005248505 NM_152622;XM_005248448 ENSP00000370611 Q7Z3K6 TRUE can 0 0 0 Metazoans 9 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr5 56218958 56242902 |NA| XP_005248505 0 FALSE 1 2 0 1.0000
168090 C6orf118 chromosome 6 open reading frame 118 6q27 12844 21233 - NP_659417;XP_005266895;XP_006715415;XP_006715416 NM_144980;XM_005266838;XM_006715352;XM_006715353;XR_427964 ENSP00000230301 Q5T5N4 TRUE can 0 0 0 Metazoans 2 -1 chr6 165693509 165715783 |bA85G2.1|dJ416F21.2| XP_005266895 0 FALSE 1 1 0 0.0000
169044 COL22A1 collagen, type XXII, alpha 1 8q24.3 9885 22989 610026 NP_690848;XP_005250867;XP_006716576 NM_152888;XM_005250810;XM_006716513 ENSP00000303153 Q8NFW1 TRUE can 0 0 0 Eukaryotes 0 -1 chr8 139601499 139895415 |NA| NP_690848 0 FALSE 2 1
169166 SNX31 sorting nexin 31 8q22.3 17545 28605 - NP_689841;XP_005250868;XP_005250869;XP_005250870;XP_005250871;XP_005250872;XP_006716577;XP_006716578;XP_006716579 NM_152628;XM_005250811;XM_005250812;XM_005250813;XM_005250814;XM_005250815;XM_006716514;XM_006716515;XM_006716516;XR_242380 ENSP00000312368 Q8N9S9 TRUE can 0 0 0 Metazoans 0 Cellular processes chr8 101586096 101661742 |NA| NP_689841 0 FALSE 1 2 21 0.0000
169966 FAM46D family with sequence similarity 46, member D Xq21.1 6643 28399 - NP_001164045;NP_689843 NM_001170574;NM_152630 ENSP00000308575 Q8NEK8 TRUE can 0 0 0 Metazoans 0 -1 chrX 79698039 79699205 |CT1.26|CT112| NP_001164045 0 FALSE 1 2 2 0.0000
170063 CXorf22 chromosome X open reading frame 22 Xp21.1 6649 28546 - NP_689845 NM_152632 ENSP00000297866 NA TRUE can 0 0 0 Eukaryotes 0 -1 chrX 35937917 36007650 |NA| NP_689845 0 FALSE 1
170261 ZCCHC12 zinc finger, CCHC domain containing 12 Xq24 6616 27273 300701 NP_776159 NM_173798 ENSP00000308921 Q6PEW1 TRUE can 0 0 1 Metazoans 0 -1 chrX 117959208 117960413 |PNMA7A|SIZN|SIZN1| NP_776159 1 FALSE 1 9 1666 0.1390
170961 ANKRD24 ankyrin repeat domain 24 19p13.3 - 29424 - NP_597732;XP_005259567;XP_006722737;XP_006722738;XP_006722739;XP_006722740;XP_006722741 NM_133475;XM_005259510;XM_006722674;XM_006722675;XM_006722676;XM_006722677;XM_006722678 ENSP00000321731 Q8TF21 TRUE can 0 0 0 Last Universal Common Ancestor 0 -1 chr19 4182666 4224499 |NA| XP_005259567 0 FALSE 1 5 49 0.0000
171017 ZNF384 zinc finger protein 384 12p12 18332 11955 609951 NP_001035009;NP_001129206;NP_597733;XP_006719026;XP_006719027;XP_006719028;XP_006719029;XP_006719030;XP_006719031;XP_006719032 NM_001039916;NM_001039917;NM_001039918;NM_001039919;NM_001039920;NM_001135734;NM_133476;XM_006718963;XM_006718964;XM_006718965;XM_006718966;XM_006718967;XM_006718968;XM_006718969 ENSP00000354592 Q8TF68 TRUE cgc 1 0 0 Eukaryotes 5 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr12 6776883 6788686 |CAGH1|CAGH1A|CIZ|ERDA2|NMP4|TNRC1| NP_001129206 0 FALSE 1 8 662 0.0360
171023 ASXL1 additional sex combs like transcriptional regulator 1 20q11 16516 18318 612990 NP_001158075;NP_056153;XP_006723790;XP_006723791;XP_006723792;XP_006723793;XP_006723794;XP_006723795;XP_006723796 NM_001164603;NM_015338;XM_006723727;XM_006723728;XM_006723729;XM_006723730;XM_006723731;XM_006723732;XM_006723733 ENSP00000364839 Q8IXJ9 TRUE cgc 0 1 0 Metazoans 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr20 30946579 31025138 |BOPS| NP_056153 0 FALSE 3 18 3432 0.2680
192670 AGO4 argonaute RISC catalytic component 4 1p34 9559 18424 607356 NP_060099;XP_005270635;XP_005270636 NM_017629;XM_005270578;XM_005270579;XR_246243;XR_246244 ENSP00000362306 Q9HCK5 TRUE can 0 0 2 Eukaryotes 4 Cellular metabolism,Regulation of transcription chr1 36282482 36319203 |EIF2C4| NP_060099 2 FALSE 1 63 23709 0.0620 1
196477 CCER1 coiled-coil glutamate-rich protein 1 12q21.33 14505 28373 - NP_689851 NM_152638 ENSP00000351727 Q8TC90 TRUE can 0 0 0 Mammals 1 -1 chr12 91347302 91348519 |C12orf12| NP_689851 0 FALSE 1 5 181 0.0000
196528 ARID2 AT rich interactive domain 2 (ARID, RFX-like) 12q12 16505 18037 609539 NP_689854;XP_006719335;XP_006719336 NM_152641;XM_006719272;XM_006719273 ENSP00000335044 Q68CP9 TRUE cgc 0 1 0 Metazoans 3 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr12 46123620 46298858 |BAF200| NP_689854 0 FALSE 5 16 168 0.4250 6
197258 FUK fucokinase 16q22.1 16365 29500 608675 NP_659496;XP_006721224;XP_006721225;XP_006721226;XP_006721227 NM_145059;XM_006721161;XM_006721162;XM_006721163;XM_006721164 ENSP00000288078 Q8N0W3 TRUE can 0 0 0 Eukaryotes 0 Cellular metabolism chr16 70497094 70513580 |1110046B12Rik| NP_659496 0 FALSE 1
199834 LCE4A late cornified envelope 4A 1q21.3 - 16613 612618 NP_848133 NM_178356 - Q5TA78 TRUE can 0 0 0 - 0 Development chr1 152681552 152681848 |LEP8|SPRL4A| NP_848133 0 FALSE 1 17 1060 0.3900
199920 C1orf168 chromosome 1 open reading frame 168 1p32.2 14120 27295 - NP_001004303;XP_005270640;XP_005270641;XP_005270642;XP_006710479 NM_001004303;XM_005270583;XM_005270584;XM_005270585;XM_006710416;XR_246247 ENSP00000345972 Q5VWT5 TRUE can 0 0 0 Vertebrates 2 -1 chr1 57185847 57258476 |NA| NP_001004303 0 FALSE 1 1 0 0.0000
200162 SPAG17 sperm associated antigen 17 1p12 10146 26620 - NP_996879;XP_006710489;XP_006710490;XP_006710491;XP_006710492;XP_006710493;XP_006710494 NM_206996;XM_006710426;XM_006710427;XM_006710428;XM_006710429;XM_006710430;XM_006710431 ENSP00000337804 Q6Q759 TRUE can 0 0 0 Metazoans 0 -1 chr1 118506425 118727780 |CT143|PF6| NP_996879 0 FALSE 1
200424 TET3 tet methylcytosine dioxygenase 3 2p13.1 - 28313 613555 NP_001274420;XP_005264244;XP_006712026 NM_001287491;NM_144993;XM_005264187;XM_006711963 ENSP00000386869 K9JJH7 TRUE can 0 0 0 Metazoans 3 -1 chr2 74213531 74329300 |NA| NP_001274420 0 FALSE 1 1 0 0.0000
201163 FLCN folliculin 17p11.2 6278 27310 607273 NP_653207;NP_659434;XP_005256572;XP_006721533 NM_144606;NM_144997;XM_005256515;XM_006721470;XR_429812 ENSP00000285071 Q8NFG4 TRUE cgc 0 1 0 Eukaryotes 4 Cell cycle,Regulation of intracellular processes and metabolism chr17 17116972 17131451 |FLCL| NP_659434 0 FALSE 1 12 2506 0.0910
201229 LYRM9 LYR motif containing 9 17q11.2 - 27314 - NP_001070148;XP_005258000;XP_005258001 NM_001076680;XM_005257943;XM_005257944 ENSP00000368396;ENSP00000462879 A8MSI8 TRUE can 0 0 0 Metazoans 0 -1 chr17 26207300 26209720 |C17orf108| NP_001070148 0 FALSE 1
202559 KHDRBS2 KH domain containing, RNA binding, signal transduction associated 2 6q11.1 13775 18114 610487 NP_689901;XP_006715417;XP_006715418 NM_152688;XM_006715354;XM_006715355;XR_427965 ENSP00000281156 Q5VWX1 TRUE can 0 0 0 Eukaryotes 2 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr6 62390871 62995853 |SLM-1|SLM1|bA535F17.1| NP_689901 0 FALSE 1 70 20839 0.0930
203447 NRK Nik related kinase Xq22.3 14841 25391 300791 NP_940867;XP_006724694;XP_006724695;XP_006724696;XP_006724697 NM_198465;XM_006724631;XM_006724632;XM_006724633;XM_006724634 ENSP00000438378 Q7Z2Y5 TRUE can 0 0 0 Eukaryotes 1 Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chrX 105066839 105199589 |NESK| NP_940867 0 FALSE 1 1 0 0.0000
219285 SAMD9L sterile alpha motif domain containing 9-like 7q21.2 10798 1349 611170 NP_689916;XP_005250248;XP_005250250;XP_006715951;XP_006715952;XP_006715953 NM_152703;XM_005250191;XM_005250193;XM_006715888;XM_006715889;XM_006715890 ENSP00000326247 Q8IVG5 TRUE can 0 0 0 Metazoans 1 -1 chr7 92760533 92765284 |C7orf6|DRIF2|UEF1| NP_689916 0 FALSE 1 1 0 0.0000
219432 OR4C6 olfactory receptor, family 4, subfamily C, member 6 11q11 17724 14743 - NP_001004704 NM_001004704 ENSP00000324769 Q8NH72 TRUE can 0 0 9 Mammals 0 Cell response to stimuli,Signal transduction chr11 55432643 55433569 |OR11-138| NP_001004704 9 TRUE 1 1
219437 OR5L1 olfactory receptor, family 5, subfamily L, member 1 11q11 15045 8350 - NP_001004738 NM_001004738 ENSP00000335529 Q8NGL2 TRUE can 0 0 2 Mammals 0 Cell response to stimuli,Signal transduction chr11 55578943 55579875 |OR11-151|OST262| NP_001004738 2 TRUE 2 1
219527 LRRC55 leucine rich repeat containing 55 11q12.1 16990 32324 615213 NP_001005210 NM_001005210 ENSP00000419542 Q6ZSA7 TRUE can 0 0 0 Eukaryotes 0 -1 chr11 56949368 56954951 |NA| NP_001005210 0 FALSE 1
219578 ZNF804B zinc finger protein 804B 7q21.13 8721 21958 - NP_857597 NM_181646 ENSP00000329638 A4D1E1 TRUE can 0 0 0 Vertebrates 1 -1 chr7 88389291 88966343 |NA| NP_857597 0 FALSE 1 1 0 0.0000
219743 TYSND1 trypsin domain containing 1 10q22.1 15593 28531 611017 NP_001035363;NP_775826 NM_001040273;NM_173555;NR_073580;NR_073581;NR_073582;NR_073591;NR_073592;NR_073593;NR_073594;NR_073595 ENSP00000287078 Q2T9J0 TRUE can 0 0 0 Eukaryotes 1 Cellular metabolism chr10 71899683 71906342 |NET41| NP_775826 0 FALSE 1 4 85 0.1670
219870 OR10G9 olfactory receptor, family 10, subfamily G, member 9 11q24.1 17666 15129 - NP_001001953 NM_001001953 ENSP00000364164 Q8NGN4 TRUE can 0 0 3 Mammals 0 Cell response to stimuli,Signal transduction chr11 123893720 123894652 |OR10G10P| NP_001001953 3 TRUE 1 1
219965 OR5B17 olfactory receptor, family 5, subfamily B, member 17 11q12.1 15036 15267 - NP_001005489 NM_001005489 ENSP00000349945 Q8NGF7 TRUE can 0 0 5 Mammals 0 Cell response to stimuli,Signal transduction chr11 58125601 58126542 |OR11-237|OR5B20P| NP_001005489 5 TRUE 1 1
219990 OOSP2 oocyte secreted protein 2 11q12.1 8207 26699 - NP_776162 NM_173801 ENSP00000278855 Q86WS3 TRUE can 0 0 0 Mammals 1 -1 chr11 59807933 59814543 |PLAC1L|TMEM122| NP_776162 0 FALSE 1 1 0 0.0000
221002 RASGEF1A RasGEF domain family, member 1A 10q11.21 15211 24246 614531 NP_001269791;NP_660356;XP_005271865;XP_005271866 NM_001282862;NM_145313;XM_005271808;XM_005271809 ENSP00000379154 Q8N9B8 TRUE can 0 0 0 Opisthokonts 1 Signal transduction chr10 43691923 43701573 |CG4853| NP_001269791 0 FALSE 1 1 0 0.0000
221061 FAM171A1 family with sequence similarity 171, member A1 10p13 18581 23522 - NP_001010924 NM_001010924 ENSP00000367356 Q5VUB5 TRUE can 0 0 0 Vertebrates 6 -1 chr10 15254917 15413051 |C10orf38| NP_001010924 0 FALSE 1 2 12 0.0000
221074 SLC39A12 solute carrier family 39 (zinc transporter), member 12 10p12.33 15384 20860 608734 NP_001138667;NP_001269662;NP_001269663;NP_689938 NM_001145195;NM_001282733;NM_001282734;NM_152725 ENSP00000366586;ENSP00000455827 Q504Y0 TRUE can 0 0 0 Last Universal Common Ancestor 1 Cellular processes chr10 18242206 18331759 |LZT-Hs8|ZIP-12|bA570F3.1| NP_001138667 0 FALSE 1
221322 TBC1D32 TBC1 domain family, member 32 6q22.31 12867 21485 615867 NP_689943;XP_005266918 NM_152730;NR_104452;XM_005266861 - Q96NH3 TRUE can 0 0 0 - 0 Regulation of intracellular processes and metabolism,Signal transduction chr6 121401920 121655576 |BROMI|C6orf170|C6orf171|bA301B7.2|bA57L9.1|dJ310J6.1| XP_005266918 0 FALSE 1
221895 JAZF1 JAZF zinc finger 1 7p15.2-p15.1 9373 28917 606246 NP_778231;XP_006715719 NM_175061;XM_006715656 ENSP00000283928 Q86VZ6 TRUE cgc 1 0 0 Opisthokonts 2 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr7 27872422 28220196 |TIP27|ZNF802| NP_778231 0 FALSE 1 3 2 0.3330
221981 THSD7A thrombospondin, type I, domain containing 7A 7p21.3 - 22207 612249 NP_056019;XP_006715722;XP_006715723;XP_006715724;XP_006715725 NM_015204;XM_006715659;XM_006715660;XM_006715661;XM_006715662 ENSP00000406482 Q9UPZ6 TRUE can 0 0 0 Eukaryotes 0 -1 chr7 11415424 11871572 |NA| NP_056019 0 FALSE 1 3 69 0.0000
222256 CDHR3 cadherin-related family member 3 7q22.3 8042 26308 615610 NP_689963;XP_005250280;XP_005250281;XP_005250282;XP_005250283;XP_006715968;XP_006715969 NM_152750;XM_005250223;XM_005250224;XM_005250225;XM_005250226;XM_006715905;XM_006715906;XR_242227 ENSP00000325954 Q6ZTQ4 TRUE can 0 0 0 Eukaryotes 0 Cell motility and interactions chr7 105603765 105673140 |CDH28| NP_689963 0 FALSE 1
222546 RFX6 regulatory factor X, 6 6q22.1 11490 21478 612659 NP_775831 NM_173560 ENSP00000332208 Q8HWS3 TRUE can 0 0 0 Opisthokonts 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr6 117198439 117252666 |MTCHRS|MTFS|RFXDC1|dJ955L16.1| NP_775831 0 FALSE 1 25 3213 0.0530
253260 RICTOR RPTOR independent companion of MTOR, complex 2 5p13.1 10682 28611 609022 NP_001272368;NP_001272369;NP_689969;XP_005248335;XP_006714526 NM_001285439;NM_001285440;NM_152756;XM_005248278;XM_006714463 ENSP00000349959 Q6R327 TRUE can 0 0 0 Eukaryotes 4 Cellular processes,Signal transduction chr5 38942409 39074479 |AVO3|PIA|hAVO3| NP_001272368 0 FALSE 1 57 14882 0.1200 5
254778 C8orf46 chromosome 8 open reading frame 46 8q13.1 14565 28498 - NP_689978 NM_152765 ENSP00000302260 Q8TAG6 TRUE can 0 0 0 Vertebrates 2 -1 chr8 67405884 67428308 |NA| NP_689978 0 FALSE 1
255057 C19orf26 chromosome 19 open reading frame 26 19p13.3 - 28617 - NP_689982;XP_005259585;XP_006722777;XP_006722778;XP_006722779 NM_152769;XM_005259528;XM_006722714;XM_006722715;XM_006722716;XR_430134 ENSP00000215376 Q8N350 TRUE can 0 0 0 Vertebrates 0 -1 chr19 1229181 1236099 |DOS| XP_005259585 0 FALSE 1 1 0 0.0000
255743 NPNT nephronectin 4q24 14141 27405 610306 NP_001028219;NP_001171619;NP_001171620;NP_001171621;NP_001171622;XP_005262945;XP_005262946;XP_005262947;XP_006714234 NM_001033047;NM_001184690;NM_001184691;NM_001184692;NM_001184693;NM_198278;XM_005262888;XM_005262889;XM_005262890;XM_006714171 ENSP00000389252 Q6UXI9 TRUE can 0 0 0 Eukaryotes 2 -1 chr4 106816810 106890144 |EGFL6L|POEM| XP_005262945 0 FALSE 1 1 0 0.0000
256281 NUDT14 nudix (nucleoside diphosphate linked moiety X)-type motif 14 14q32.33 14847 20141 609219 NP_803877;XP_005267556;XP_005267557 NM_177533;XM_005267499;XM_005267500 ENSP00000376349 O95848 TRUE can 0 0 0 Last Universal Common Ancestor 0 -1 chr14 105639361 105647546 |UGPP|UGPPase| NP_803877 0 FALSE 1 9 729 0.0830
256435 ST6GALNAC3 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 1p31.1 15341 19343 610133 NP_001153483;NP_694541;XP_006710616;XP_006710617 NM_001160011;NM_152996;XM_006710553;XM_006710554;XR_426597 ENSP00000329214 Q8NDV1 TRUE can 0 0 0 Eukaryotes 0 Cellular metabolism,Cellular processes chr1 76779484 77094488 |PRO7177|SIAT7C|ST6GALNACIII| NP_694541 0 FALSE 1
256646 NUTM1 NUT midline carcinoma, family member 1 15q14 10606 29919 608963 NP_001271221;NP_001271222;NP_786883 NM_001284292;NM_001284293;NM_175741 ENSP00000329448 Q86Y26 TRUE cgc 1 0 0 Vertebrates 1 -1 chr15 34638143 34649689 |C15orf55|FAM22H|NUT| NP_001271221 0 FALSE 1 23 5755 0.0080
259173 ALS2CL ALS2 C-terminal like 3p21.31 10643 20605 612402 NP_001177636;NP_667340;NP_877576;XP_005265082;XP_006713151;XP_006713152;XP_006713153;XP_006713154;XP_006713155;XP_006713156;XP_006713157;XP_006713158;XP_006713159 NM_001190707;NM_147129;NM_182775;NR_033815;XM_005265025;XM_006713088;XM_006713089;XM_006713090;XM_006713091;XM_006713092;XM_006713093;XM_006713094;XM_006713095;XM_006713096;XR_427263;XR_427264;XR_427265 ENSP00000313670 Q60I27 TRUE can 0 0 0 Last Universal Common Ancestor 0 Cellular processes chr3 46712477 46730930 |RN49018| NP_001177636 0 FALSE 1 1 0 0.0000
259232 NALCN sodium leak channel, non-selective 13q32.3 15647 19082 611549 NP_443099;XP_006720006;XP_006720007;XP_006720008 NM_052867;XM_006719943;XM_006719944;XM_006719945 ENSP00000251127 Q8IZF0 TRUE can 0 0 0 Eukaryotes 1 Cellular processes chr13 101707650 102051477 |CanIon|INNFD|VGCNL1|bA430M15.1| NP_443099 0 FALSE 1 1 0 0.0000
259283 MDS2 myelodysplastic syndrome 2 translocation associated 1p36 - 29633 607305 - NR_027042 - NA TRUE cgc 1 0 -1 - 0 -1 - 0 0 |NA| - -1 FALSE 1
260293 CYP4X1 cytochrome P450, family 4, subfamily X, polypeptide 1 1p33|1 13110 20244 614999 NP_828847 NM_178033 ENSP00000360968 Q8N118 TRUE can 0 0 0 Last Universal Common Ancestor 0 -1 chr1 47489490 47515843 |CYPIVX1| NP_828847 0 FALSE 1
282770 OR10AG1 olfactory receptor, family 10, subfamily AG, member 1 11q11 14885 19607 - NP_001005491 NM_001005491 ENSP00000311477 Q8NH19 TRUE can 0 0 0 Vertebrates 0 Cell response to stimuli,Signal transduction chr11 55735037 55735939 |OR11-160| NP_001005491 0 TRUE 1 1
283092 OR4C13 olfactory receptor, family 4, subfamily C, member 13 11p11.12 17720 15169 - NP_001001955 NM_001001955 - Q8NGP0 TRUE can 0 0 12 - 0 Cell response to stimuli,Signal transduction chr11 49973975 49974901 |NA| NP_001001955 12 TRUE 1 1
283310 OTOGL otogelin-like 12q21.31 8815 26901 614925 NP_775862;XP_005268859 NM_173591;XM_005268802 ENSP00000400895 A0A0A0MSS2 TRUE can 0 0 0 Eukaryotes 1 Cellular metabolism chr12 80603191 80771825 |C12orf64|DFNB84B| XP_005268859 0 FALSE 1
283316 CD163L1 CD163 molecule-like 1 12p13.3 7301 30375 606079 NP_777601;XP_005253405;XP_006719124 NM_174941;XM_005253348;XM_006719061;XR_429032 ENSP00000315945 Q9NR16 TRUE can 0 0 0 Eukaryotes 0 -1 chr12 7510003 7593843 |CD163B|M160| XP_005253405 0 FALSE 1
283383 GPR133 G protein-coupled receptor 133 12q24.33 17061 19893 613639 NP_942122;XP_005253623;XP_006719409;XP_006719410 NM_198827;XM_005253566;XM_006719346;XM_006719347;XR_429090 ENSP00000261654 Q6QNK2 TRUE can 0 0 0 Eukaryotes 0 Signal transduction chr12 131439011 131623805 |PGR25| NP_942122 0 FALSE 1
283464 GXYLT1 glucoside xylosyltransferase 1 12q12 - 27482 613321 NP_001093120;NP_775872 NM_001099650;NM_173601 ENSP00000381666 Q4G148 TRUE can 0 0 4 Eukaryotes 5 Cellular metabolism chr12 42481591 42538448 |GLT8D3| NP_775872 4 FALSE 1 4 17 0.1670
283651 HMGN2P46 high mobility group nucleosomal binding domain 2 pseudogene 46 15q21.1 - 26817 611314 - NM_001005266;NM_001005267;NM_001005268;NM_001005269;NM_173609;NR_022014 - NA TRUE cgc 1 0 -1 - 0 -1 - 0 0 |C15orf21|D-PCa-2| - -1 FALSE 1
284391 ZNF844 zinc finger protein 844 19p13.2 - - - NP_001129973;XP_006722790;XP_006722791;XP_006722792 NM_001136501;XM_006722727;XM_006722728;XM_006722729 ENSP00000392024 Q08AG5 TRUE can 0 0 0 Eukaryotes 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr19 12184846 12187933 |NA| NP_001129973 0 FALSE 1 5 211 0.2000
284521 OR2L13 olfactory receptor, family 2, subfamily L, member 13 1q44 - 19578 - NP_787107 NM_175911 ENSP00000350836 Q8N349 TRUE can 0 0 6 Vertebrates 0 Cell response to stimuli,Signal transduction chr1 248262678 248263613 |OR2L14| NP_787107 6 TRUE 1 1 0 0.0000 1
284525 SLC9C2 solute carrier family 9, member C2 (putative) 1q25.1 15398 28664 - NP_848622 NM_178527 ENSP00000356687 Q5TAH2 TRUE can 0 0 0 Eukaryotes 0 Cellular processes,Regulation of intracellular processes and metabolism chr1 173472407 173570915 |SLC9A11| NP_848622 0 FALSE 1
285175 UNC80 unc-80 homolog (C. elegans) 2q35 12809 26582 612636 NP_115893;NP_872393;XP_005246533;XP_006712508;XP_006712509;XP_006712510;XP_006712511;XP_006712512;XP_006712513;XP_006712514;XP_006712515 NM_032504;NM_182587;XM_005246476;XM_006712445;XM_006712446;XM_006712447;XM_006712448;XM_006712449;XM_006712450;XM_006712451;XM_006712452 ENSP00000391088 Q8N2C7 TRUE can 0 0 0 Metazoans 0 -1 chr2 210636797 210860316 |C2orf21|UNC-80| XP_005246533 0 FALSE 1 4 191 0.1670
285313 IGSF10 immunoglobulin superfamily, member 10 3q25.1 - 26384 - NP_001171616;NP_001171617;NP_849144;XP_005247434;XP_006713659;XP_006713660;XP_006713661;XP_006713662;XP_006713663 NM_001178145;NM_001178146;NM_178822;XM_005247377;XM_006713596;XM_006713597;XM_006713598;XM_006713599;XM_006713600 ENSP00000282466 Q6WRI0 TRUE can 0 0 0 Eukaryotes 2 Cellular metabolism,Cellular processes,Development chr3 151154480 151176497 |CMF608| NP_849144 0 FALSE 2 1 0 0.0000
286499 FAM133A family with sequence similarity 133, member A Xq21.32 6562 26748 - NP_001164580;NP_001164581;NP_001164582;NP_775969;XP_006724704 NM_001171109;NM_001171110;NM_001171111;NM_173698;XM_006724641 ENSP00000318974 Q8N9E0 TRUE can 0 0 3 Metazoans 3 -1 chrX 92964419 92965162 |CT115| NP_001164580 3 FALSE 1 8 229 0.0710
286530 P2RY8 purinergic receptor P2Y, G-protein coupled, 8 Xp22.33; Yp11.3 6671 15524 300525 NP_835230;XP_005274486;XP_005274487;XP_005274835;XP_005274836;XP_006724506;XP_006724927 NM_178129;XM_005274429;XM_005274430;XM_005274778;XM_005274779;XM_006724443;XM_006724864 ENSP00000370697 Q86VZ1 TRUE cgc 1 0 1 Vertebrates 0 Signal transduction chrX 1584375 1585451 |P2Y8| NP_835230 1 FALSE 2
317703 VN1R4 vomeronasal 1 receptor 4 19q13.42 18287 19871 - NP_776256 NM_173857 ENSP00000310856 Q7Z5H5 TRUE can 0 0 1 Mammals 0 Signal transduction chr19 53770016 53770918 |V1RL4| NP_776256 1 FALSE 1
317754 POTED POTE ankyrin domain family, member D 21q11.2 9612 23822 607549 NP_778146;XP_006724060 NM_174981;XM_006723997 ENSP00000299443;ENSP00000457689 NA TRUE can 0 0 10 Last Universal Common Ancestor 0 -1 chr21 14982550 15013884 |A26B3|ANKRD21|CT104.1|POTE|POTE-21|POTE21| NP_778146 10 FALSE 1
337976 KRTAP20-2 keratin associated protein 20-2 21q22.1 - 18944 - NP_853647 NM_181616 - Q3LI61 TRUE can 0 0 0 - 0 -1 chr21 32007583 32007777 |KAP20.2| NP_853647 0 FALSE 1
338398 TAS2R60 taste receptor, type 2, member 60 7q35 18159 20639 613968 NP_803186 NM_177437 ENSP00000327724 P59551 TRUE can 0 0 0 Mammals 0 Cell response to stimuli,Signal transduction chr7 143140546 143141499 |T2R60| NP_803186 0 FALSE 1 2
338645 LUZP2 leucine zipper protein 2 11p14.3 17348 23206 608178 NP_001009909;NP_001238937;NP_001238939;XP_005252944;XP_005252947 NM_001009909;NM_001252008;NM_001252010;XM_005252887;XM_005252890 ENSP00000336817 Q86TE4 TRUE can 0 0 0 Vertebrates 0 -1 chr11 24518790 25100201 |KFSP2566|PRO6246| NP_001009909 0 FALSE 1
339145 FAM92B family with sequence similarity 92, member B 16q24.1 13488 24781 - NP_940893;XP_005255988 NM_198491;XM_005255931 ENSP00000443411 Q6ZTR7 TRUE can 0 0 0 Vertebrates 0 -1 chr16 85132794 85144068 |NA| NP_940893 0 FALSE 1
339479 BRINP3 bone morphogenetic protein/retinoic acid inducible neural-specific 3 1q31.1 16782 22393 - NP_950252;XP_005245174;XP_005245175;XP_005245176;XP_005245177;XP_005245180 NM_199051;XM_005245117;XM_005245118;XM_005245119;XM_005245120;XM_005245123 ENSP00000356432 Q76B58 TRUE can 0 0 0 Metazoans 0 -1 chr1 190067151 190424020 |DBCCR1L|DBCCR1L1|FAM5C| NP_950252 0 FALSE 2 1 0 0.0000
339967 TMPRSS11A transmembrane protease, serine 11A 4q13.2 7123 27954 611704 NP_001107859;NP_872412;XP_006714269 NM_001114387;NM_182606;XM_006714206 ENSP00000334611 Q6ZMR5 TRUE can 0 0 0 Last Universal Common Ancestor 3 Cellular metabolism chr4 68777063 68812291 |ECRG1| NP_872412 0 FALSE 1 1 0 0.0000
339970 GCOM2 GRINL1B complex locus 2, pseudogene 4q12 - - 608311 - - ENSP00000299638 NA TRUE can 0 0 -1 Vertebrates 0 -1 - 0 0 |GLURR2|GRINL1B| - -1 FALSE 1
340273 ABCB5 ATP-binding cassette, sub-family B (MDR/TAP), member 5 7p21.1 - 46 611785 NP_001157413;NP_001157414;NP_001157465;NP_848654;XP_006715785 NM_001163941;NM_001163942;NM_001163993;NM_178559;XM_006715722 ENSP00000384881 Q2M3G0 TRUE can 0 0 0 Last Universal Common Ancestor 2 -1 chr7 20662909 20795244 |ABCB5alpha|ABCB5beta|EST422562| NP_001157413 0 FALSE 1 2 0 1.0000
340419 RSPO2 R-spondin 2 8q23.1 17536 28583 610575 NP_001269792;NP_848660;XP_005250963;XP_005250964 NM_001282863;NM_178565;XM_005250906;XM_005250907 ENSP00000276659 Q6UXX9 TRUE can 0 0 0 Eukaryotes 1 Signal transduction chr8 108913306 109094866 |CRISTIN2| NP_848660 0 FALSE 1 7 1383 0.0480 3
340578 DCAF12L2 DDB1 and CUL4 associated factor 12-like 2 Xq25 - 32950 - NP_001013650 NM_001013628 ENSP00000353128 Q5VW00 TRUE can 0 0 1 Eukaryotes 0 -1 chrX 125298519 125299907 |WDR40C| NP_001013650 1 FALSE 1 2 0 1.0000
341350 OVCH1 ovochymase 1 12p11.22 7138 23080 - NP_899234 NM_183378 ENSP00000326708 Q7RTY7 TRUE can 0 0 0 Last Universal Common Ancestor 0 Cellular metabolism chr12 29586684 29650619 |OVCH| NP_899234 0 FALSE 1
341359 SYT10 synaptotagmin X 12p11.1 - 19266 - NP_945343 NM_198992 ENSP00000228567 Q6XYQ8 TRUE can 0 0 0 Eukaryotes 0 -1 chr12 33529768 33592457 |NA| NP_945343 0 FALSE 1
341640 FREM2 FRAS1 related extracellular matrix protein 2 13q13.3 10602 25396 608945 NP_997244 NM_207361 ENSP00000280481 Q5SZK8 TRUE can 0 0 0 Last Universal Common Ancestor 1 Cell motility and interactions chr13 39261482 39454921 |NA| NP_997244 0 FALSE 1 2 39 0.0000
343171 OR2W3 olfactory receptor, family 2, subfamily W, member 3 1q44 17714 15021 - NP_001001957 NM_001001957 ENSP00000353516 Q7Z3T1 TRUE can 0 0 1 Mammals 0 Cell response to stimuli,Signal transduction chr1 248058889 248059830 |OR2W3P|OR2W8P|OST718| NP_001001957 1 TRUE 1 1
343406 OR10R2 olfactory receptor, family 10, subfamily R, member 2 1q23.1 17674 14820 - NP_001004472 NM_001004472 ENSP00000357134 Q8NGX6 TRUE can 0 0 1 Mammals 0 Signal transduction chr1 158449668 158450672 |OR1-8|OR10R2Q| NP_001004472 1 TRUE 1 1
345930 ECT2L epithelial cell transforming 2 like 6q24.1 - 21118 - NP_001071174;NP_001181966;XP_006715535 NM_001077706;NM_001195037;XM_006715472 ENSP00000356655 Q008S8 TRUE cgc 0 1 0 Eukaryotes 0 Signal transduction chr6 139134412 139223761 |ARHGEF32|C6orf91|FBXO49|LFDH|dJ509I19.2|dJ509I19.3|dJ509I19.5| NP_001071174 0 FALSE 1
346007 EYS eyes shut homolog (Drosophila) 6q12 16853 21555 612424 NP_001136272;NP_001136273;NP_938024 NM_001142800;NM_001142801;NM_198283 ENSP00000424243 Q5T1H1 TRUE can 0 0 0 Eukaryotes 3 -1 chr6 64430495 66205303 |C6orf178|C6orf179|C6orf180|EGFL10|EGFL11|RP25|SPAM|bA166P24.2|bA307F22.3|bA74E24.1|dJ1018A4.2|dJ22I17.2|dJ303F19.1| NP_001136272 0 TRUE 2
346157 ZNF391 zinc finger protein 391 6p22.1 - 18779 - NP_001070249;XP_005249139;XP_006715149 NM_001013719;NM_001076781;XM_005249082;XM_006715086 ENSP00000244576 Q9UJN7 TRUE can 0 0 0 Eukaryotes 0 Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr6 27368150 27369223 |dJ153G14.3| NP_001070249 0 FALSE 1 5 117 0.0000
347730 LRRTM1 leucine rich repeat transmembrane neuronal 1 2p12 14323 19408 610867 NP_849161 NM_178839;XR_244930;XR_244931 ENSP00000295057 Q86UE6 TRUE can 0 0 0 Last Universal Common Ancestor 3 -1 chr2 80529379 80530944 |NA| NP_849161 0 FALSE 1
348980 HCN1 hyperpolarization activated cyclic nucleotide-gated potassium channel 1 5p12 - 4845 602780 NP_066550;XP_006714535 NM_021072;XM_006714472 ENSP00000307342 O60741 TRUE can 0 0 0 Eukaryotes 0 Cellular processes chr5 45262026 45696195 |BCNG-1|BCNG1|EIEE24|HAC-2| NP_066550 0 FALSE 1 4 82 0.3330
353332 KRTAP12-1 keratin associated protein 12-1 21q22.3 11197 20529 - NP_859014 NM_181686 ENSP00000375475 P59990 TRUE can 0 0 -1 Mammals 0 -1 - 0 0 |KAP12.1|KRTAP12.1| - -1 FALSE 1
374393 FAM111B family with sequence similarity 111, member B 11q12.1 7096 24200 615584 NP_001136175;NP_001136176;NP_945185 NM_001142703;NM_001142704;NM_198947 ENSP00000341565 Q6SJ93 TRUE can 0 0 0 Vertebrates 1 -1 chr11 58877099 58893772 |POIKTMP| NP_945185 0 FALSE 1 4 482 0.0000
374819 LRRC37A3 leucine rich repeat containing 37, member A3 17q24.1 - 32427 - NP_955372 NM_199340 ENSP00000325713;ENSP00000469814 O60309 TRUE can 0 0 4 Vertebrates 0 -1 chr17 62850720 62893375 |NA| NP_955372 4 FALSE 1
374864 CCDC178 coiled-coil domain containing 178 18q12.1 12691 29588 - NP_001098998;NP_945346 NM_001105528;NM_198995 ENSP00000372576 Q5BJE1 TRUE can 0 0 0 Vertebrates 0 -1 chr18 30517978 30992052 |C18orf34| NP_001098998 0 FALSE 1
375033 PEAR1 platelet endothelial aggregation receptor 1 1q23.1 - 33631 610278 NP_001073940;XP_005245198;XP_006711364;XP_006711365;XP_006711366 NM_001080471;NM_207369;XM_005245141;XM_006711301;XM_006711302;XM_006711303 ENSP00000292357 Q5VY43 TRUE can 0 0 0 Eukaryotes 0 -1 chr1 156873719 156884587 |JEDI|MEGF12| NP_001073940 0 FALSE 1
375248 ANKRD36 ankyrin repeat domain 36 2q11.2 16492 24079 - NP_001157787;XP_005263994;XP_005263995;XP_006712577;XP_006712578;XP_006712579;XP_006712580 NM_001164315;NM_198555;XM_005263937;XM_005263938;XM_006712514;XM_006712515;XM_006712516;XM_006712517;XR_427086 ENSP00000391950 A6QL64 TRUE can 0 0 2 Last Universal Common Ancestor 0 -1 chr2 97779477 97915382 |UNQ2430| NP_001157787 2 FALSE 1
375775 PNPLA7 patatin-like phospholipase domain containing 7 9q34.3 12933 24768 612122 NP_001092007;NP_689499;XP_005266136;XP_005266139;XP_006717165;XP_006717166;XP_006717167 NM_001098537;NM_152286;XM_005266079;XM_005266082;XM_006717102;XM_006717103;XM_006717104 ENSP00000384610 Q6ZV29 TRUE can 0 0 0 Last Universal Common Ancestor 0 -1 chr9 140354848 140442114 |C9orf111|NTE-R1|NTEL1| NP_001092007 0 FALSE 1
378938 MALAT1 metastasis associated lung adenocarcinoma transcript 1 (non-protein coding) 11q13.1 - 29665 607924 - NR_002819 - NA TRUE cgc 1 0 -1 - 0 -1 - 0 0 |HCN|LINC00047|MALAT-1|NCRNA00047|NEAT2|PRO2853|mascRNA| - -1 FALSE 1
386617 KCTD8 potassium channel tetramerization domain containing 8 4p13 13771 22394 - NP_938167 NM_198353 ENSP00000353129 Q6ZWB6 TRUE can 0 0 0 Eukaryotes 0 Cellular processes chr4 44176810 44450540 |NA| NP_938167 0 FALSE 1 2 0 1.0000
388468 POTEC POTE ankyrin domain family, member C 18p11.21 - 33894 - NP_001131143 NM_001137671 ENSP00000299443;ENSP00000457689 B2RU33 TRUE can 0 0 12 Last Universal Common Ancestor 0 -1 chr18 14511826 14543145 |A26B2|CT104.6|POTE-18|POTE18| NP_997238 12 FALSE 1
388591 RNF207 ring finger protein 207 1p36.31 8119 32947 - NP_997279;XP_006710701;XP_006710702 NM_173795;NM_207396;XM_006710638;XM_006710639 ENSP00000367173 Q6ZRF8 TRUE can 0 0 0 Metazoans 0 -1 chr1 6266596 6279464 |C1orf188| NP_997279 0 FALSE 1
388633 LDLRAD1 low density lipoprotein receptor class A domain containing 1 1p32.3 - 32069 - NP_001010978;NP_001263321;NP_001263322;NP_001263323;NP_001263324;XP_006710704;XP_006710705 NM_001010978;NM_001276392;NM_001276393;NM_001276394;NM_001276395;XM_006710641;XM_006710642 ENSP00000360411 Q5T700 TRUE can 0 0 0 Vertebrates 0 -1 chr1 54474658 54483103 |NA| NP_001010978 0 FALSE 1 15 14860 0.0100
388677 NOTCH2NL notch 2 N-terminal like 1q21.2 - 31862 - NP_982283 NM_203458 ENSP00000354929;ENSP00000462298;ENSP00000464060 NA TRUE can 0 0 -1 Eukaryotes 0 Signal transduction - 0 0 |N2N| - -1 FALSE 1
389197 C4orf50 chromosome 4 open reading frame 50 4p16.2 - 33766 - XP_003118572;XP_003119970;XP_003960384 NM_207405;XM_003118524;XM_003119922;XM_003960335 ENSP00000437121 NA TRUE can 0 0 0 Mammals 0 -1 chr4 5961105 5991900 |NA| XP_003118572 0 FALSE 1
389692 MAFA v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog A 8q24.3 14346 23145 610303 NP_963883 NM_201589 ENSP00000349477 Q8NHW3 TRUE can 0 0 0 Eukaryotes 0 Cell response to stimuli,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction chr8 144511518 144512576 |RIPE3b1|hMafA| NP_963883 0 FALSE 1 5 57 0.3000
390064 OR51I2 olfactory receptor, family 51, subfamily I, member 2 11p15.4 15000 15201 - NP_001004754 NM_001004754 ENSP00000341987 Q9H344 TRUE can 0 0 1 Mammals 0 Cell response to stimuli,Signal transduction chr11 5474719 5475654 |OR11-38| NP_001004754 1 TRUE 1 1
390079 OR52E8 olfactory receptor, family 52, subfamily E, member 8 11p15.4 15013 15217 - NP_001005168 NM_001005168 ENSP00000444054 Q6IFG1 TRUE can 0 0 6 Mammals 0 Cell response to stimuli,Signal transduction chr11 5877982 5878932 |OR11-54| NP_001005168 6 TRUE 1 1
390151 OR8H2 olfactory receptor, family 8, subfamily H, member 2 11q12.1 15083 15308 - NP_001005200 NM_001005200 ENSP00000323982 Q8N162 TRUE can 0 0 2 Vertebrates 0 Cell response to stimuli,Signal transduction chr11 55872519 55873454 |OR11-171| NP_001005200 2 TRUE 1 1 0 0.0000 1
390155 OR5T1 olfactory receptor, family 5, subfamily T, member 1 11q12.1 15050 14821 - NP_001004745 NM_001004745 ENSP00000323612;ENSP00000459132 Q8NG75 TRUE can 0 0 2 Vertebrates 0 Cell response to stimuli,Signal transduction chr11 56043115 56044092 |OR11-179|OR5T1P| NP_001004745 2 TRUE 1 1 0 0.0000 1
390157 OR8K1 olfactory receptor, family 8, subfamily K, member 1 11q12.1 15086 14831 - NP_001002907 NM_001002907 ENSP00000279783;ENSP00000461384 Q8NGG5 TRUE can 0 0 3 Mammals 0 Cell response to stimuli,Signal transduction chr11 56113515 56114471 |OR11-182|OR8N1P| NP_001002907 3 TRUE 1 1
390265 OR10G7 olfactory receptor, family 10, subfamily G, member 7 11q24.2 14890 14842 - NP_001004463 NM_001004463 ENSP00000329689 Q8NGN6 TRUE can 0 0 4 Mammals 0 Cell response to stimuli,Signal transduction chr11 123908776 123909708 |OR11-283| NP_001004463 4 TRUE 1 1
391114 OR6K3 olfactory receptor, family 6, subfamily K, member 3 1q23.1 15064 15030 - NP_001005327 NM_001005327 ENSP00000357127 Q8NGY3 TRUE can 0 0 2 Mammals 0 Signal transduction chr1 158686961 158687905 |OR1-18| NP_001005327 2 TRUE 1 1
391189 OR11L1 olfactory receptor, family 11, subfamily L, member 1 1q44 17677 14998 - NP_001001959 NM_001001959 ENSP00000348033 Q8NGX0 TRUE can 0 0 0 Last Universal Common Ancestor 0 Cell response to stimuli,Signal transduction chr1 248004233 248005198 |NA| NP_001001959 0 TRUE 1 1
391195 OR2T33 olfactory receptor, family 2, subfamily T, member 33 1q44 14953 31255 - NP_001004695 NM_001004695 ENSP00000324687 Q8NG76 TRUE can 0 0 3 Mammals 0 Cell response to stimuli,Signal transduction chr1 248436157 248437116 |OR1-56| NP_001004695 3 TRUE 1 1
392232 LOC392232 transient receptor potential cation channel, subfamily A, member 1 pseudogene 8q13.3 - - - - NR_033867 - NA TRUE can 0 0 -1 - 0 -1 - 0 0 |LOC392232| - -1 FALSE 1
402317 OR2A42 olfactory receptor, family 2, subfamily A, member 42 7q35 18486 31230 - NP_001001802 NM_001001802 ENSP00000375334;ENSP00000386175 NA TRUE can 0 0 10 Vertebrates 0 Cell response to stimuli,Cellular metabolism,Signal transduction chr7 144015218 144016147 |NA| NP_001001802 10 TRUE 1 1
414059 TBC1D3B TBC1 domain family, member 3B 17q12 11264 27011 610144 NP_001001417;XP_005258037;XP_006725386 NM_001001417;XM_005257980;XM_006725323 ENSP00000381781;ENSP00000409195;ENSP00000456382 A6NDS4 TRUE can 0 0 -1 Eukaryotes 0 Regulation of intracellular processes and metabolism,Signal transduction - 0 0 |TBC1D3I| - -1 FALSE 1
425054 VCX3B variable charge, X-linked 3B Xp22.31 15646 31838 - NP_001001888 NM_001001888 ENSP00000370420;ENSP00000370447;ENSP00000370479 Q9H321 TRUE can 0 0 2 Primates 0 Development,Multicellular activities chrX 8433492 8434421 |VCX-C|VCXC| NP_001001888 2 FALSE 1
439915 KRTAP5-5 keratin associated protein 5-5 11p15.5 - - - NP_001001480;XP_003846592;XP_006725597 NM_001001480;XM_003846544;XM_006725534 - Q701N2 TRUE can 0 0 14 - 0 -1 chr11 1651071 1651781 |KRTAP5.5| NP_001001480 7 FALSE 1
440093 H3F3C H3 histone, family 3C 12p11.21 18443 33164 - NP_001013721 NM_001013699 ENSP00000339835 Q6NXT2 TRUE can 0 0 33 Last Universal Common Ancestor 2 DNA/RNA metabolism and transcription chr12 31944696 31945100 |H3.5| NP_001013721 33 FALSE 1 12 775 0.0300
440275 EIF2AK4 eukaryotic translation initiation factor 2 alpha kinase 4 15q15.1 18447 19687 609280 NP_001013725;XP_005254449;XP_005254450 NM_001013703;XM_005254392;XM_005254393 ENSP00000263791 Q9P2K8 TRUE can 0 0 0 Last Universal Common Ancestor 0 Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription chr15 40226397 40327282 |GCN2|PVOD2| NP_001013725 0 FALSE 1 16 963 0.2000
440279 UNC13C unc-13 homolog C (C. elegans) 15q21.3 - - 614568 NP_001074003;XP_005254451;XP_005254452 NM_001080534;XM_005254394;XM_005254395 ENSP00000260323 Q8NB66 TRUE can 0 0 0 Metazoans 2 Cellular processes,Signal transduction chr15 54305101 54919308 |NA| NP_001074003 0 FALSE 3
442361 OR2A2 olfactory receptor, family 2, subfamily A, member 2 7q35 14931 8230 - NP_001005480 NM_001005480 ENSP00000386209 Q6IF42 TRUE can 0 0 8 Vertebrates 0 Cell response to stimuli,Signal transduction chr7 143806676 143807629 |OR2A17P|OR2A2P|OR7-11|OST008| NP_001005480 8 TRUE 1 1
494119 SPANXN2 SPANX family, member N2 Xq27.3 18091 33175 300665 NP_001009615 NM_001009615 ENSP00000359529;ENSP00000470584 Q5MJ10 TRUE can 0 0 3 Primates 0 -1 chrX 142795138 142803762 |CT11.7|SPANX-N2| NP_001009615 3 FALSE 1
641977 SEPT7P2 septin 7 pseudogene 2 7p12.3 - 32339 611563 - NR_024271 - NA TRUE can 0 0 -1 - 0 -1 - 0 0 |SEPT13|SEPT7B| - -1 FALSE 1
644591 PPIAL4G peptidylprolyl isomerase A (cyclophilin A)-like 4G 1q21.1 - - - NP_001116540 NM_001123068 ENSP00000393845;ENSP00000463057 NA TRUE can 0 0 67 Last Universal Common Ancestor 0 Cellular metabolism,Cellular processes chr1 143767357 143767848 |NA| NP_001116540 67 FALSE 1
646450 ARIH2OS ariadne homolog 2 opposite strand 3p21.31 - 34425 - NP_001116512 NM_001123040 ENSP00000386193 Q8N7S6 TRUE can 0 0 0 Mammals 0 -1 chr3 48955713 48956582 |C3orf71| NP_001116512 0 FALSE 1
653247 PRB2 proline-rich protein BstNI subfamily 2 12p13.2 18511 9338 168810 NP_006239 NM_006248 - NA TRUE can 0 0 10 - 3 Signal transduction chr12 11545764 11547465 |IB-9|PRPPRB1|Ps|cP7| NP_006239 10 FALSE 1
653390 RRN3P2 RNA polymerase I transcription factor homolog (S. cerevisiae) pseudogene 2 16p11.2 - 37619 - - NR_003369 - NA TRUE can 0 0 -1 - 0 -1 - 0 0 |NA| - -1 FALSE 1
727832 GOLGA6L6 golgin A6 family-like 6 15q11.2 - 37225 - NP_001138476 NM_001145004 ENSP00000398615 A0A087WWN6 TRUE can 0 0 3 Primates 0 -1 chr15 20739500 20747023 |NA| NP_001138476 3 FALSE 1
728118 NUTM2A NUT family member 2A 10q23.2 - 23438 - NP_001092808;XP_005270168 NM_001099338;XM_005270111 ENSP00000371126 Q8IVF1 TRUE cgc 1 0 5 Mammals 1 -1 chr10 88985588 88994462 |FAM22A| NP_001092808 5 FALSE 1
728276 CLEC19A C-type lectin domain family 19, member A 16p12.3 - - - NP_001243649 NM_001256720;NR_024436 ENSP00000455948 NA TRUE can 0 0 0 Eukaryotes 0 -1 chr16 19297174 19320402 |NA| NP_001243649 0 FALSE 1
729262 NUTM2B NUT family member 2B 10q22.3 - 23445 - NP_001265424;XP_005270192 NM_001278495;XM_005270135 ENSP00000394623 A6NNL0 TRUE cgc 1 0 5 Mammals 1 -1 chr10 81463366 81472238 |FAM22B|bA119F19.1| NP_001265424 5 FALSE 1 1 0 0.0000
100129108 LOC100129108 tripartite motif containing 64B pseudogene 11p11.12 - - - - - - NA TRUE can 0 0 -1 - 0 -1 - 0 0 |LOC100129108| - -1 FALSE 1
100271849 MEF2B myocyte enhancer factor 2B 19p13.11 - 6995 600661 NP_001139257 NM_001145785 ENSP00000162023 A0A024R7K5 TRUE can 0 0 0 Eukaryotes 0 -1 chr19 19256609 19261544 |RSRFR2| NP_001139257 0 FALSE 1 4 19 0.1670
100302214 MIR1277 microRNA 1277 Xq24 - 35350 - - NR_031685 - NA TRUE can 0 0 -1 - 0 -1 - 0 0 |MIRN1277|hsa-mir-1277| - -1 FALSE 1
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