Custom user colors by user mode. Only effects the chat, not the userlist.

color_ranks.py

import hexchat

__module_name__ = 'color ranks'
__module_author__ = 'Yama'
__module_version__ = '0.1'
__module_description__ = 'Make user colors by rank'

def mod_colors(word, word_eol, userdata):
    nickname = hexchat.strip(word[0], len(word[0]), 1)
    nickname += '\003'
    message = word[1]
    if len(word) > 2:
        mode = word[2]
        if mode in ('&', '@', '%'):
            color = '\0034'
        elif mode == '~':
            color = '\0035'
        elif mode == '+':
            color = '\00314'
        mode = color + mode
    else:
        mode = '\0033'

    hexchat.prnt('<{}{}> {}'.format(mode, nickname, message))
    return hexchat.EAT_ALL

hexchat.hook_print('Channel Message', mod_colors)