-
-
Save PritiShaw/3eb9aa6d1823813080a9d59cb94b3cd0 to your computer and use it in GitHub Desktop.
This file contains bidirectional Unicode text that may be interpreted or compiled differently than what appears below. To review, open the file in an editor that reveals hidden Unicode characters.
Learn more about bidirectional Unicode characters
<!DOCTYPE html> | |
<html lang="en"> | |
<head> | |
<meta charset="utf-8"> | |
<meta http-equiv="X-UA-Compatible" content="IE=edge"> | |
<meta name="viewport" content="width=device-width, initial-scale=1"> | |
<!-- The above 3 meta tags *must* come first in the head; any other head content must come *after* these tags --> | |
<meta name="description" content=""> | |
<meta name="author" content=""> | |
<link rel="icon" href="https://bigmech.s3.amazonaws.com/indra-db/favicon.ico"> | |
<title>INDRA Results</title> | |
<script src="https://code.jquery.com/jquery-3.3.1.min.js" | |
integrity="sha256-FgpCb/KJQlLNfOu91ta32o/NMZxltwRo8QtmkMRdAu8=" | |
crossorigin="anonymous"></script> | |
<!-- Latest compiled and minified CSS --> | |
<link rel="stylesheet" | |
href="https://stackpath.bootstrapcdn.com/bootstrap/4.1.3/css/bootstrap.min.css" | |
integrity="sha384-MCw98/SFnGE8fJT3GXwEOngsV7Zt27NXFoaoApmYm81iuXoPkFOJwJ8ERdknLPMO" | |
crossorigin="anonymous"> | |
<!-- Optional theme --> | |
<link rel="stylesheet" | |
href="https://use.fontawesome.com/releases/v5.5.0/css/all.css" | |
integrity="sha384-B4dIYHKNBt8Bc12p+WXckhzcICo0wtJAoU8YZTY5qE0Id1GSseTk6S+L3BlXeVIU" | |
crossorigin="anonymous"> | |
<!-- Latest compiled and minified JavaScript --> | |
<script src="https://stackpath.bootstrapcdn.com/bootstrap/4.1.3/js/bootstrap.min.js" | |
integrity="sha384-ChfqqxuZUCnJSK3+MXmPNIyE6ZbWh2IMqE241rYiqJxyMiZ6OW/JmZQ5stwEULTy" | |
crossorigin="anonymous"></script> | |
<style> | |
a { | |
color: #256DC5; | |
target-new: tab; | |
} | |
h1 { | |
margin-bottom: 0; | |
} | |
.page-header { | |
padding: 1em; | |
} | |
</style> | |
<!-- Toggle a hidden element --> | |
<script> | |
const pubmed_fetch = "https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi"; | |
let ALL_COLLAPSED = true; | |
function toggler(short_name_key) { | |
$("#" + short_name_key + "_group").toggle(); | |
let header = "#" + short_name_key + "_heading"; | |
$(header).show(); | |
} | |
function getPubMedMETAxmlByPMID(pmid) { | |
let params_dict = { | |
'db': 'pubmed', | |
'retmode': 'xml', | |
'rettype': 'docsum', | |
'id': pmid | |
}; | |
return $.ajax({ | |
url: pubmed_fetch, | |
type: "POST", | |
dataType: "xml", | |
data: params_dict, | |
}); | |
} | |
function pmidXML2dict(XML) { | |
let xml_dict = {}; | |
for (let child of XML.children) { | |
let name = child.getAttribute("Name"); | |
let type = child.getAttribute("Type"); | |
if (child.hasChildNodes() && type === "List") { | |
let innerItems; | |
// Javascript can't really do nice recursive functions... | |
// special cases for "History" and "ArticleIds" which has unique inner Names | |
if (name === "ArticleIds" || name === "History") { | |
let innerDict = {}; | |
for (c of child.children) { | |
innerDict[c.getAttribute("Name")] = c.textContent; | |
} | |
innerItems = innerDict; | |
} else { | |
let innerList = []; | |
for (c of child.children) { | |
innerList.push(c.textContent); | |
} | |
innerItems = innerList; | |
} | |
xml_dict[name] = innerItems | |
} else if (child.tagName === "Item") { | |
// Here just get the inner strings | |
xml_dict[name] = child.textContent; | |
} else if (child.tagName === "Id") { | |
// Special case | |
xml_dict["Id"] = child.textContent; | |
} else { | |
if (!xml_dict["no_key"]) { | |
xml_dict["no_key"] = [child.textContent] | |
} else { | |
xml_dict["no_key"].push(child.textContent) | |
} | |
} | |
} | |
return xml_dict; | |
} | |
// Modify link hover text | |
function setPMIDlinkTitle(pmid, link_tag) { | |
let pubmed_xml_promise = getPubMedMETAxmlByPMID(pmid); | |
pubmed_xml_promise.then(responseXML => { | |
const docsum_xml = responseXML.getElementsByTagName('DocSum')[0]; | |
const pmd = pmidXML2dict(docsum_xml); | |
const nAuthors = pmd.AuthorList.length; | |
let authorsStr; | |
if (nAuthors > 3) | |
authorsStr = `${pmd.AuthorList[0]}, ... ${pmd.AuthorList[nAuthors - 1]}`; | |
else | |
authorsStr = pmd.AuthorList.join(", "); | |
// Shortened journal name is in .Source, while full name is in .FullJournalName | |
link_tag.title = `${authorsStr}, "${pmd.Title}", ${pmd.Source}, ${pmd.SO}`; | |
}) | |
} | |
// Loop all pmid link nodes and set title | |
function populatePMIDlinkTitles() { | |
let pmid_link_array = document.getElementsByClassName("pmid_link"); | |
for (link_obj of pmid_link_array) { | |
pmid = link_obj.textContent; | |
setPMIDlinkTitle(pmid, link_obj) | |
} | |
} | |
// Open journal in PubmedCentral | |
function openPMCIDJournal(pmcid, html){ | |
var span = document.createElement('span'); | |
span.innerHTML = html; | |
var text = span.innerText; | |
window.open("https://www.ncbi.nlm.nih.gov/pmc/articles/"+pmcid+"?text="+ encodeURIComponent(text)) | |
} | |
// Expand/collapse all | |
function expandCollapseAll() { | |
let expColBtn = document.getElementById('expand-collapse-all'); | |
let setCss = ''; | |
// Expand all; set ALL_COLLAPSED = false; | |
if (ALL_COLLAPSED) { | |
setCss = 'display: block;'; | |
ALL_COLLAPSED = false; | |
expColBtn.textContent = 'Collapse All'; | |
// Collapse all; set ALL_COLLAPSED = true; | |
} else { | |
setCss = 'display: none;'; | |
ALL_COLLAPSED = true; | |
expColBtn.textContent = 'Expand All'; | |
} | |
// Loop all tags | |
for (tag of document.getElementsByClassName('group')) { | |
tag.style.cssText = setCss | |
} | |
} | |
</script> | |
<style> | |
.source-phosphosite { | |
background-color: #bc80bd; | |
color: black; | |
} | |
.source-cbn { | |
background-color: #fccde5; | |
color: black; | |
} | |
.source-pc11 { | |
background-color: #b3de69; | |
color: black; | |
} | |
.source-biopax { | |
background-color: #80b1d3; | |
color: black; | |
} | |
.source-bel_lc { | |
background-color: #fb8072; | |
color: black; | |
} | |
.source-signor { | |
background-color: #bebada; | |
color: black; | |
} | |
.source-biogrid { | |
background-color: #fdb462; | |
color: black; | |
} | |
.source-tas { | |
background-color: #8dd3c7; | |
color: black; | |
} | |
.source-lincs_drug { | |
background-color: #ffffb3; | |
color: black; | |
} | |
.source-hprd { | |
background-color: #d9d9d9; | |
color: black; | |
} | |
.source-trrust { | |
background-color: #ccebc5; | |
color: black; | |
} | |
.source-geneways { | |
background-color: #bc80bd; | |
color: white; | |
} | |
.source-tees { | |
background-color: #fccde5; | |
color: white; | |
} | |
.source-isi { | |
background-color: #b3de69; | |
color: white; | |
} | |
.source-trips { | |
background-color: #80b1d3; | |
color: white; | |
} | |
.source-rlimsp { | |
background-color: #fb8072; | |
color: white; | |
} | |
.source-medscan { | |
background-color: #bebada; | |
color: white; | |
} | |
.source-sparser { | |
background-color: #fdb462; | |
color: white; | |
} | |
.source-reach { | |
background-color: #8dd3c7; | |
color: white; | |
} | |
.badge-source { | |
font-size: 8pt; | |
margin: 0; | |
} | |
.statements-header { | |
position: -webkit-sticky; | |
position: sticky; | |
top: 0; | |
background-color: white; | |
z-index: 10; | |
padding-top: 5px; | |
} | |
.nvp { | |
padding-left: 0; | |
padding-right: 0; | |
} | |
.src-api { | |
overflow-x: hidden; | |
} | |
.group, .group-shown { | |
padding: 5px; | |
margin: 5px; | |
} | |
.group { | |
display: none; | |
border-left: #0d5aa7 solid 1px; | |
border-right: #0d5aa7 solid 1px; | |
} | |
.super_group_heading, .group_heading, .statement, .evidence { | |
padding: 2px; | |
padding-left: 5px; | |
margin: 2px; | |
position: sticky; | |
border-radius: 2px; | |
} | |
.evidence, .evidence-text { | |
margin-bottom: 10px; | |
} | |
.evidence-text { | |
border-top: #cfcfcf solid 1px; | |
padding-top: 0.5em; | |
} | |
.super_group_heading, .group_heading { | |
cursor: pointer; | |
} | |
.super_group_heading:hover, .group_heading:hover { | |
background-color: #f2f2f2; | |
} | |
.badge-subject { | |
background-color: #4a36aa; | |
color: #FFFFFF; | |
} | |
.badge-object { | |
background-color: #2d8e4c; | |
color: #FFFFFF; | |
} | |
.badge-other { | |
background-color: #606060; | |
color: #FFFFFF; | |
} | |
.curation-row { | |
overflow-y: hidden; | |
} | |
.curation_toggle { | |
cursor: pointer; | |
} | |
.pmid_link, .pmcid_link, .doi_link { | |
display: block; | |
} | |
.full_text_search:hover { | |
text-decoration: underline; | |
} | |
</style> | |
</head> | |
<body> | |
<div class="container"> | |
<!-- Page Header --> | |
<div class="page-header"> | |
<h1>INDRA Results</h1> | |
</div> | |
This page allows you to curate the loaded statements. For more information | |
please see the | |
<a href="https://indra.readthedocs.io/en/latest/tutorials/html_curation.html" | |
target="_blank">manual</a>. | |
<hr> | |
<div class="statements-header"> | |
<div class="row"> | |
<div class="col"> | |
<h3 > | |
Statements | |
</h3> | |
</div> | |
<div class="col text-right"> | |
<button id="expand-collapse-all" type="button" | |
class="btn btn-primary" | |
onclick="expandCollapseAll()"> | |
Expand All | |
</button> | |
</div> | |
</div> | |
<hr> | |
</div> | |
<div class="row super_group_heading" | |
id="tl-37647242-7e59-4309-880d-9f6cc39714f4" | |
onclick="toggler('tl-37647242-7e59-4309-880d-9f6cc39714f4')"> | |
<div class="col nvp"> | |
<h5 class="align-middle"> | |
<a href='https://identifiers.org/chebi/CHEBI:49470' target='_blank'>Aluminium(3+)</a> affects <a href='https://identifiers.org/go/GO:0006955' target='_blank'>immune response</a> | |
</h5> | |
</div> | |
<div class="col text-right nvp"> | |
</div> | |
</div> | |
<div class="group" id="tl-37647242-7e59-4309-880d-9f6cc39714f4_group"> | |
<div class="container nvp"> | |
<div class="row group-shown" id="904d9c54-4ef4-4b7b-a2d0-b01804bd240b_group"> | |
<div class="container nvp"> | |
<a name="-10301112258491834"></a> | |
<div class="row statement"> | |
<div class="col text-left nvp"> | |
<h5 class="align-middle"> | |
<a href='https://identifiers.org/chebi/CHEBI:49470' target='_blank'>Aluminium(3+)</a> activates <a href='https://identifiers.org/go/GO:0006955' target='_blank'>immune response</a>. | |
<a href="#" | |
> | |
<small class="badge badge-secondary badge-pill">1</small> | |
</a> | |
</h5> | |
</div> | |
<div class="col text-right nvp"> | |
</div> | |
</div> | |
<div class="row evidence"> | |
<div class="container" id="stmt-0-0-0" | |
data-stmt_hash="-10301112258491834"> | |
<div class="row evidence-text" data-source_hash="8490993238778999406" | |
style="border-bottom: 1px solid #FFFFFF;" | |
id="ev-0-0-0-0"> | |
<div class="col-1"> | |
<div class="row"> | |
<div class="col-3 nvp curation_toggle" | |
id="ev-0-0-0-0-click" | |
data-parent_id="ev-0-0-0-0"> | |
<a href="#" | |
> | |
➶ | |
</a> | |
</div> | |
<div class="col-9 nvp src-api" | |
title="reach"> | |
reach | |
</div> | |
</div> | |
</div> | |
<div class="col-9"> | |
"We further characterized the <span class="badge badge-object">immune response</span> induced by the formulation that provided the highest protection against invasive lethal challenge and compared it to the <span class="badge badge-object">immune response</span> induced by Combo5 / <span class="badge badge-subject">alum</span> and M1/<span class="badge badge-subject">alum</span>." | |
</div> | |
<div class="col-2 text-right"> | |
<a class="pmid_link" | |
title="Hover again to see info" | |
onmouseover="setPMIDlinkTitle(this.textContent, this); this.onmouseover=null;" | |
href='https://www.ncbi.nlm.nih.gov/pubmed/32156809' | |
target="_blank"> | |
32156809</a> | |
| <a class="pmcid_link full_text_search" | |
onclick='openPMCIDJournal(`PMC7064752`, `We further characterized the <span class="badge badge-object">immune response</span> induced by the formulation that provided the highest protection against invasive lethal challenge and compared it to the <span class="badge badge-object">immune response</span> induced by Combo5 / <span class="badge badge-subject">alum</span> and M1/<span class="badge badge-subject">alum</span>.` );' | |
href="javascript:;">Full-Text Search: PMC7064752</a> | |
</div> | |
</div> | |
</div> <!-- container --> | |
</div> <!-- row evidence --> | |
</div> <!-- PA Statement container --> | |
</div> <!-- PA Statement group --> | |
</div> <!-- container --> | |
</div> <!-- type groups --> | |
<div class="row super_group_heading" | |
id="tl-fe24ee06-4f41-4b6d-918a-6a0d37516186" | |
onclick="toggler('tl-fe24ee06-4f41-4b6d-918a-6a0d37516186')"> | |
<div class="col nvp"> | |
<h5 class="align-middle"> | |
SMQ affects TNF-α | |
</h5> | |
</div> | |
<div class="col text-right nvp"> | |
</div> | |
</div> | |
<div class="group" id="tl-fe24ee06-4f41-4b6d-918a-6a0d37516186_group"> | |
<div class="container nvp"> | |
<div class="row group-shown" id="3260a5fc-2f9c-4b8b-85d3-37da286b05bd_group"> | |
<div class="container nvp"> | |
<a name="-25651963520341412"></a> | |
<div class="row statement"> | |
<div class="col text-left nvp"> | |
<h5 class="align-middle"> | |
SMQ activates TNF-α. | |
<a href="#" | |
> | |
<small class="badge badge-secondary badge-pill">1</small> | |
</a> | |
</h5> | |
</div> | |
<div class="col text-right nvp"> | |
</div> | |
</div> | |
<div class="row evidence"> | |
<div class="container" id="stmt-1-0-0" | |
data-stmt_hash="-25651963520341412"> | |
<div class="row evidence-text" data-source_hash="4155885927386739680" | |
style="border-bottom: 1px solid #FFFFFF;" | |
id="ev-1-0-0-0"> | |
<div class="col-1"> | |
<div class="row"> | |
<div class="col-3 nvp curation_toggle" | |
id="ev-1-0-0-0-click" | |
data-parent_id="ev-1-0-0-0"> | |
<a href="#" | |
> | |
➶ | |
</a> | |
</div> | |
<div class="col-9 nvp src-api" | |
title="reach"> | |
reach | |
</div> | |
</div> | |
</div> | |
<div class="col-9"> | |
"A comparison between the cytokine concentrations secreted by splenocytes from Combo5 / alum and Combo5 / <span class="badge badge-subject">SMQ</span> immune mice showed that the <span class="badge badge-subject">SMQ</span> adjuvanted formulation induced significantly higher secretion of IL-6, IL-10, IFN-γ, and <span class="badge badge-object">TNF-α</span> than the alum adjuvanted formulation." | |
</div> | |
<div class="col-2 text-right"> | |
<a class="pmid_link" | |
title="Hover again to see info" | |
onmouseover="setPMIDlinkTitle(this.textContent, this); this.onmouseover=null;" | |
href='https://www.ncbi.nlm.nih.gov/pubmed/32156809' | |
target="_blank"> | |
32156809</a> | |
| <a class="pmcid_link full_text_search" | |
onclick='openPMCIDJournal(`PMC7064752`, `A comparison between the cytokine concentrations secreted by splenocytes from Combo5 / alum and Combo5 / <span class="badge badge-subject">SMQ</span> immune mice showed that the <span class="badge badge-subject">SMQ</span> adjuvanted formulation induced significantly higher secretion of IL-6, IL-10, IFN-γ, and <span class="badge badge-object">TNF-α</span> than the alum adjuvanted formulation.` );' | |
href="javascript:;">Full-Text Search: PMC7064752</a> | |
</div> | |
</div> | |
</div> <!-- container --> | |
</div> <!-- row evidence --> | |
</div> <!-- PA Statement container --> | |
</div> <!-- PA Statement group --> | |
</div> <!-- container --> | |
</div> <!-- type groups --> | |
<div class="row super_group_heading" | |
id="tl-d5196a9b-4c5e-4d13-813b-2a262c6a1801" | |
onclick="toggler('tl-d5196a9b-4c5e-4d13-813b-2a262c6a1801')"> | |
<div class="col nvp"> | |
<h5 class="align-middle"> | |
SMQ affects <a href='https://identifiers.org/hgnc/HGNC:6018' target='_blank'>IL6</a> | |
</h5> | |
</div> | |
<div class="col text-right nvp"> | |
</div> | |
</div> | |
<div class="group" id="tl-d5196a9b-4c5e-4d13-813b-2a262c6a1801_group"> | |
<div class="container nvp"> | |
<div class="row group-shown" id="d2e4c2d0-edea-4418-83dc-3bb7349d6622_group"> | |
<div class="container nvp"> | |
<a name="-17919606370707517"></a> | |
<div class="row statement"> | |
<div class="col text-left nvp"> | |
<h5 class="align-middle"> | |
SMQ activates <a href='https://identifiers.org/hgnc/HGNC:6018' target='_blank'>IL6</a>. | |
<a href="#" | |
> | |
<small class="badge badge-secondary badge-pill">1</small> | |
</a> | |
</h5> | |
</div> | |
<div class="col text-right nvp"> | |
</div> | |
</div> | |
<div class="row evidence"> | |
<div class="container" id="stmt-2-0-0" | |
data-stmt_hash="-17919606370707517"> | |
<div class="row evidence-text" data-source_hash="4155885927386739680" | |
style="border-bottom: 1px solid #FFFFFF;" | |
id="ev-2-0-0-0"> | |
<div class="col-1"> | |
<div class="row"> | |
<div class="col-3 nvp curation_toggle" | |
id="ev-2-0-0-0-click" | |
data-parent_id="ev-2-0-0-0"> | |
<a href="#" | |
> | |
➶ | |
</a> | |
</div> | |
<div class="col-9 nvp src-api" | |
title="reach"> | |
reach | |
</div> | |
</div> | |
</div> | |
<div class="col-9"> | |
"A comparison between the cytokine concentrations secreted by splenocytes from Combo5 / alum and Combo5 / <span class="badge badge-subject">SMQ</span> immune mice showed that the <span class="badge badge-subject">SMQ</span> adjuvanted formulation induced significantly higher secretion of <span class="badge badge-object">IL-6</span>, IL-10, IFN-γ, and TNF-α than the alum adjuvanted formulation." | |
</div> | |
<div class="col-2 text-right"> | |
<a class="pmid_link" | |
title="Hover again to see info" | |
onmouseover="setPMIDlinkTitle(this.textContent, this); this.onmouseover=null;" | |
href='https://www.ncbi.nlm.nih.gov/pubmed/32156809' | |
target="_blank"> | |
32156809</a> | |
| <a class="pmcid_link full_text_search" | |
onclick='openPMCIDJournal(`PMC7064752`, `A comparison between the cytokine concentrations secreted by splenocytes from Combo5 / alum and Combo5 / <span class="badge badge-subject">SMQ</span> immune mice showed that the <span class="badge badge-subject">SMQ</span> adjuvanted formulation induced significantly higher secretion of <span class="badge badge-object">IL-6</span>, IL-10, IFN-γ, and TNF-α than the alum adjuvanted formulation.` );' | |
href="javascript:;">Full-Text Search: PMC7064752</a> | |
</div> | |
</div> | |
</div> <!-- container --> | |
</div> <!-- row evidence --> | |
</div> <!-- PA Statement container --> | |
</div> <!-- PA Statement group --> | |
</div> <!-- container --> | |
</div> <!-- type groups --> | |
<div class="row super_group_heading" | |
id="tl-3c759c4a-d031-42b0-9f67-5f9fe8fe0827" | |
onclick="toggler('tl-3c759c4a-d031-42b0-9f67-5f9fe8fe0827')"> | |
<div class="col nvp"> | |
<h5 class="align-middle"> | |
SMQ affects <a href='https://identifiers.org/hgnc/HGNC:5962' target='_blank'>IL10</a> | |
</h5> | |
</div> | |
<div class="col text-right nvp"> | |
</div> | |
</div> | |
<div class="group" id="tl-3c759c4a-d031-42b0-9f67-5f9fe8fe0827_group"> | |
<div class="container nvp"> | |
<div class="row group-shown" id="ba1a9b42-32e5-4069-95c4-599248fb18fc_group"> | |
<div class="container nvp"> | |
<a name="30554384213470801"></a> | |
<div class="row statement"> | |
<div class="col text-left nvp"> | |
<h5 class="align-middle"> | |
SMQ activates <a href='https://identifiers.org/hgnc/HGNC:5962' target='_blank'>IL10</a>. | |
<a href="#" | |
> | |
<small class="badge badge-secondary badge-pill">1</small> | |
</a> | |
</h5> | |
</div> | |
<div class="col text-right nvp"> | |
</div> | |
</div> | |
<div class="row evidence"> | |
<div class="container" id="stmt-3-0-0" | |
data-stmt_hash="30554384213470801"> | |
<div class="row evidence-text" data-source_hash="4155885927386739680" | |
style="border-bottom: 1px solid #FFFFFF;" | |
id="ev-3-0-0-0"> | |
<div class="col-1"> | |
<div class="row"> | |
<div class="col-3 nvp curation_toggle" | |
id="ev-3-0-0-0-click" | |
data-parent_id="ev-3-0-0-0"> | |
<a href="#" | |
> | |
➶ | |
</a> | |
</div> | |
<div class="col-9 nvp src-api" | |
title="reach"> | |
reach | |
</div> | |
</div> | |
</div> | |
<div class="col-9"> | |
"A comparison between the cytokine concentrations secreted by splenocytes from Combo5 / alum and Combo5 / <span class="badge badge-subject">SMQ</span> immune mice showed that the <span class="badge badge-subject">SMQ</span> adjuvanted formulation induced significantly higher secretion of IL-6, <span class="badge badge-object">IL-10</span>, IFN-γ, and TNF-α than the alum adjuvanted formulation." | |
</div> | |
<div class="col-2 text-right"> | |
<a class="pmid_link" | |
title="Hover again to see info" | |
onmouseover="setPMIDlinkTitle(this.textContent, this); this.onmouseover=null;" | |
href='https://www.ncbi.nlm.nih.gov/pubmed/32156809' | |
target="_blank"> | |
32156809</a> | |
| <a class="pmcid_link full_text_search" | |
onclick='openPMCIDJournal(`PMC7064752`, `A comparison between the cytokine concentrations secreted by splenocytes from Combo5 / alum and Combo5 / <span class="badge badge-subject">SMQ</span> immune mice showed that the <span class="badge badge-subject">SMQ</span> adjuvanted formulation induced significantly higher secretion of IL-6, <span class="badge badge-object">IL-10</span>, IFN-γ, and TNF-α than the alum adjuvanted formulation.` );' | |
href="javascript:;">Full-Text Search: PMC7064752</a> | |
</div> | |
</div> | |
</div> <!-- container --> | |
</div> <!-- row evidence --> | |
</div> <!-- PA Statement container --> | |
</div> <!-- PA Statement group --> | |
</div> <!-- container --> | |
</div> <!-- type groups --> | |
<div class="row super_group_heading" | |
id="tl-9f6196e4-7d73-4e47-826b-1d2649d1fd03" | |
onclick="toggler('tl-9f6196e4-7d73-4e47-826b-1d2649d1fd03')"> | |
<div class="col nvp"> | |
<h5 class="align-middle"> | |
SMQ affects IFN-γ | |
</h5> | |
</div> | |
<div class="col text-right nvp"> | |
</div> | |
</div> | |
<div class="group" id="tl-9f6196e4-7d73-4e47-826b-1d2649d1fd03_group"> | |
<div class="container nvp"> | |
<div class="row group-shown" id="3b9e1ee8-2a64-4acb-9407-0081f84a656a_group"> | |
<div class="container nvp"> | |
<a name="13465087121692280"></a> | |
<div class="row statement"> | |
<div class="col text-left nvp"> | |
<h5 class="align-middle"> | |
SMQ activates IFN-γ. | |
<a href="#" | |
> | |
<small class="badge badge-secondary badge-pill">1</small> | |
</a> | |
</h5> | |
</div> | |
<div class="col text-right nvp"> | |
</div> | |
</div> | |
<div class="row evidence"> | |
<div class="container" id="stmt-4-0-0" | |
data-stmt_hash="13465087121692280"> | |
<div class="row evidence-text" data-source_hash="4155885927386739680" | |
style="border-bottom: 1px solid #FFFFFF;" | |
id="ev-4-0-0-0"> | |
<div class="col-1"> | |
<div class="row"> | |
<div class="col-3 nvp curation_toggle" | |
id="ev-4-0-0-0-click" | |
data-parent_id="ev-4-0-0-0"> | |
<a href="#" | |
> | |
➶ | |
</a> | |
</div> | |
<div class="col-9 nvp src-api" | |
title="reach"> | |
reach | |
</div> | |
</div> | |
</div> | |
<div class="col-9"> | |
"A comparison between the cytokine concentrations secreted by splenocytes from Combo5 / alum and Combo5 / <span class="badge badge-subject">SMQ</span> immune mice showed that the <span class="badge badge-subject">SMQ</span> adjuvanted formulation induced significantly higher secretion of IL-6, IL-10, <span class="badge badge-object">IFN-γ</span>, and TNF-α than the alum adjuvanted formulation." | |
</div> | |
<div class="col-2 text-right"> | |
<a class="pmid_link" | |
title="Hover again to see info" | |
onmouseover="setPMIDlinkTitle(this.textContent, this); this.onmouseover=null;" | |
href='https://www.ncbi.nlm.nih.gov/pubmed/32156809' | |
target="_blank"> | |
32156809</a> | |
| <a class="pmcid_link full_text_search" | |
onclick='openPMCIDJournal(`PMC7064752`, `A comparison between the cytokine concentrations secreted by splenocytes from Combo5 / alum and Combo5 / <span class="badge badge-subject">SMQ</span> immune mice showed that the <span class="badge badge-subject">SMQ</span> adjuvanted formulation induced significantly higher secretion of IL-6, IL-10, <span class="badge badge-object">IFN-γ</span>, and TNF-α than the alum adjuvanted formulation.` );' | |
href="javascript:;">Full-Text Search: PMC7064752</a> | |
</div> | |
</div> | |
</div> <!-- container --> | |
</div> <!-- row evidence --> | |
</div> <!-- PA Statement container --> | |
</div> <!-- PA Statement group --> | |
</div> <!-- container --> | |
</div> <!-- type groups --> | |
<div class="row super_group_heading" | |
id="tl-e7c84fd6-4341-4cdf-af52-4d53ea2cd73f" | |
onclick="toggler('tl-e7c84fd6-4341-4cdf-af52-4d53ea2cd73f')"> | |
<div class="col nvp"> | |
<h5 class="align-middle"> | |
<a href='https://identifiers.org/chebi/CHEBI:51079' target='_blank'>GS26575</a> affects <a href='https://identifiers.org/hgnc/HGNC:4164' target='_blank'>GAST</a> | |
</h5> | |
</div> | |
<div class="col text-right nvp"> | |
</div> | |
</div> | |
<div class="group" id="tl-e7c84fd6-4341-4cdf-af52-4d53ea2cd73f_group"> | |
<div class="container nvp"> | |
<div class="row group-shown" id="9cf74aef-9073-41b0-895d-51655ee916f8_group"> | |
<div class="container nvp"> | |
<a name="-31029788656818151"></a> | |
<div class="row statement"> | |
<div class="col text-left nvp"> | |
<h5 class="align-middle"> | |
<a href='https://identifiers.org/chebi/CHEBI:51079' target='_blank'>GS26575</a> activates <a href='https://identifiers.org/hgnc/HGNC:4164' target='_blank'>GAST</a>. | |
<a href="#" | |
> | |
<small class="badge badge-secondary badge-pill">1</small> | |
</a> | |
</h5> | |
</div> | |
<div class="col text-right nvp"> | |
</div> | |
</div> | |
<div class="row evidence"> | |
<div class="container" id="stmt-5-0-0" | |
data-stmt_hash="-31029788656818151"> | |
<div class="row evidence-text" data-source_hash="-5164385967986893407" | |
style="border-bottom: 1px solid #FFFFFF;" | |
id="ev-5-0-0-0"> | |
<div class="col-1"> | |
<div class="row"> | |
<div class="col-3 nvp curation_toggle" | |
id="ev-5-0-0-0-click" | |
data-parent_id="ev-5-0-0-0"> | |
<a href="#" | |
> | |
➶ | |
</a> | |
</div> | |
<div class="col-9 nvp src-api" | |
title="reach"> | |
reach | |
</div> | |
</div> | |
</div> | |
<div class="col-9"> | |
"Only <span class="badge badge-subject">M1</span> immune sera was able to promote opsonophagocytic killing of <span class="badge badge-object">GAS</span> (XREF_FIG) with an opsonic index significantly higher than that measured for naive mice." | |
</div> | |
<div class="col-2 text-right"> | |
<a class="pmid_link" | |
title="Hover again to see info" | |
onmouseover="setPMIDlinkTitle(this.textContent, this); this.onmouseover=null;" | |
href='https://www.ncbi.nlm.nih.gov/pubmed/32156809' | |
target="_blank"> | |
32156809</a> | |
| <a class="pmcid_link full_text_search" | |
onclick='openPMCIDJournal(`PMC7064752`, `Only <span class="badge badge-subject">M1</span> immune sera was able to promote opsonophagocytic killing of <span class="badge badge-object">GAS</span> (XREF_FIG) with an opsonic index significantly higher than that measured for naive mice.` );' | |
href="javascript:;">Full-Text Search: PMC7064752</a> | |
</div> | |
</div> | |
</div> <!-- container --> | |
</div> <!-- row evidence --> | |
</div> <!-- PA Statement container --> | |
</div> <!-- PA Statement group --> | |
</div> <!-- container --> | |
</div> <!-- type groups --> | |
<div class="row super_group_heading" | |
id="tl-764b485b-d8f0-4df9-b48b-16e5cdf28b55" | |
onclick="toggler('tl-764b485b-d8f0-4df9-b48b-16e5cdf28b55')"> | |
<div class="col nvp"> | |
<h5 class="align-middle"> | |
Combo5 affects <a href='https://identifiers.org/go/GO:0006955' target='_blank'>immune response</a> | |
</h5> | |
</div> | |
<div class="col text-right nvp"> | |
</div> | |
</div> | |
<div class="group" id="tl-764b485b-d8f0-4df9-b48b-16e5cdf28b55_group"> | |
<div class="container nvp"> | |
<div class="row group-shown" id="471570d0-b7a7-4a22-9bd4-f931d4f1afbe_group"> | |
<div class="container nvp"> | |
<a name="-12695682573761343"></a> | |
<div class="row statement"> | |
<div class="col text-left nvp"> | |
<h5 class="align-middle"> | |
Combo5 activates <a href='https://identifiers.org/go/GO:0006955' target='_blank'>immune response</a>. | |
<a href="#" | |
> | |
<small class="badge badge-secondary badge-pill">1</small> | |
</a> | |
</h5> | |
</div> | |
<div class="col text-right nvp"> | |
</div> | |
</div> | |
<div class="row evidence"> | |
<div class="container" id="stmt-6-0-0" | |
data-stmt_hash="-12695682573761343"> | |
<div class="row evidence-text" data-source_hash="597975201937205239" | |
style="border-bottom: 1px solid #FFFFFF;" | |
id="ev-6-0-0-0"> | |
<div class="col-1"> | |
<div class="row"> | |
<div class="col-3 nvp curation_toggle" | |
id="ev-6-0-0-0-click" | |
data-parent_id="ev-6-0-0-0"> | |
<a href="#" | |
> | |
➶ | |
</a> | |
</div> | |
<div class="col-9 nvp src-api" | |
title="reach"> | |
reach | |
</div> | |
</div> | |
</div> | |
<div class="col-9"> | |
"We further characterized the protective <span class="badge badge-object">immune response</span> elicited by <span class="badge badge-subject">Combo5</span> formulated with SMQ adjuvant and compared this to the nonprotective response elicited by <span class="badge badge-subject">Combo5</span> / alum and to the protective response elicited by the “ gold standard ” homologous M1 protein formulated with alum." | |
</div> | |
<div class="col-2 text-right"> | |
<a class="pmid_link" | |
title="Hover again to see info" | |
onmouseover="setPMIDlinkTitle(this.textContent, this); this.onmouseover=null;" | |
href='https://www.ncbi.nlm.nih.gov/pubmed/32156809' | |
target="_blank"> | |
32156809</a> | |
| <a class="pmcid_link full_text_search" | |
onclick='openPMCIDJournal(`PMC7064752`, `We further characterized the protective <span class="badge badge-object">immune response</span> elicited by <span class="badge badge-subject">Combo5</span> formulated with SMQ adjuvant and compared this to the nonprotective response elicited by <span class="badge badge-subject">Combo5</span> / alum and to the protective response elicited by the “ gold standard ” homologous M1 protein formulated with alum.` );' | |
href="javascript:;">Full-Text Search: PMC7064752</a> | |
</div> | |
</div> | |
</div> <!-- container --> | |
</div> <!-- row evidence --> | |
</div> <!-- PA Statement container --> | |
</div> <!-- PA Statement group --> | |
</div> <!-- container --> | |
</div> <!-- type groups --> | |
<hr> | |
<!-- Footer --> | |
<footer class="footer text-muted" id="about"> | |
<h5 class="my-0 mr-md-auto font-weight-normal">About</h5> | |
INDRA is developed by <a href="https://indralab.github.io/">indralabs</a>, | |
a part of the Harvard Medical School Laboratory of Systems Pharmacology. | |
</footer> | |
</div> | |
</body> | |
</html> |
This file contains bidirectional Unicode text that may be interpreted or compiled differently than what appears below. To review, open the file in an editor that reveals hidden Unicode characters.
Learn more about bidirectional Unicode characters
<!DOCTYPE html> | |
<html lang="en"> | |
<head> | |
<meta charset="utf-8"> | |
<meta http-equiv="X-UA-Compatible" content="IE=edge"> | |
<meta name="viewport" content="width=device-width, initial-scale=1"> | |
<!-- The above 3 meta tags *must* come first in the head; any other head content must come *after* these tags --> | |
<meta name="description" content=""> | |
<meta name="author" content=""> | |
<link rel="icon" href="https://bigmech.s3.amazonaws.com/indra-db/favicon.ico"> | |
<title>INDRA Results</title> | |
<script src="https://code.jquery.com/jquery-3.3.1.min.js" | |
integrity="sha256-FgpCb/KJQlLNfOu91ta32o/NMZxltwRo8QtmkMRdAu8=" | |
crossorigin="anonymous"></script> | |
<!-- Latest compiled and minified CSS --> | |
<link rel="stylesheet" | |
href="https://stackpath.bootstrapcdn.com/bootstrap/4.1.3/css/bootstrap.min.css" | |
integrity="sha384-MCw98/SFnGE8fJT3GXwEOngsV7Zt27NXFoaoApmYm81iuXoPkFOJwJ8ERdknLPMO" | |
crossorigin="anonymous"> | |
<!-- Optional theme --> | |
<link rel="stylesheet" | |
href="https://use.fontawesome.com/releases/v5.5.0/css/all.css" | |
integrity="sha384-B4dIYHKNBt8Bc12p+WXckhzcICo0wtJAoU8YZTY5qE0Id1GSseTk6S+L3BlXeVIU" | |
crossorigin="anonymous"> | |
<!-- Latest compiled and minified JavaScript --> | |
<script src="https://stackpath.bootstrapcdn.com/bootstrap/4.1.3/js/bootstrap.min.js" | |
integrity="sha384-ChfqqxuZUCnJSK3+MXmPNIyE6ZbWh2IMqE241rYiqJxyMiZ6OW/JmZQ5stwEULTy" | |
crossorigin="anonymous"></script> | |
<style> | |
a { | |
color: #256DC5; | |
target-new: tab; | |
} | |
h1 { | |
margin-bottom: 0; | |
} | |
.page-header { | |
padding: 1em; | |
} | |
</style> | |
<!-- Toggle a hidden element --> | |
<script> | |
const pubmed_fetch = "https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi"; | |
let ALL_COLLAPSED = true; | |
function toggler(short_name_key) { | |
$("#" + short_name_key + "_group").toggle(); | |
let header = "#" + short_name_key + "_heading"; | |
$(header).show(); | |
} | |
function getPubMedMETAxmlByPMID(pmid) { | |
let params_dict = { | |
'db': 'pubmed', | |
'retmode': 'xml', | |
'rettype': 'docsum', | |
'id': pmid | |
}; | |
return $.ajax({ | |
url: pubmed_fetch, | |
type: "POST", | |
dataType: "xml", | |
data: params_dict, | |
}); | |
} | |
function pmidXML2dict(XML) { | |
let xml_dict = {}; | |
for (let child of XML.children) { | |
let name = child.getAttribute("Name"); | |
let type = child.getAttribute("Type"); | |
if (child.hasChildNodes() && type === "List") { | |
let innerItems; | |
// Javascript can't really do nice recursive functions... | |
// special cases for "History" and "ArticleIds" which has unique inner Names | |
if (name === "ArticleIds" || name === "History") { | |
let innerDict = {}; | |
for (c of child.children) { | |
innerDict[c.getAttribute("Name")] = c.textContent; | |
} | |
innerItems = innerDict; | |
} else { | |
let innerList = []; | |
for (c of child.children) { | |
innerList.push(c.textContent); | |
} | |
innerItems = innerList; | |
} | |
xml_dict[name] = innerItems | |
} else if (child.tagName === "Item") { | |
// Here just get the inner strings | |
xml_dict[name] = child.textContent; | |
} else if (child.tagName === "Id") { | |
// Special case | |
xml_dict["Id"] = child.textContent; | |
} else { | |
if (!xml_dict["no_key"]) { | |
xml_dict["no_key"] = [child.textContent] | |
} else { | |
xml_dict["no_key"].push(child.textContent) | |
} | |
} | |
} | |
return xml_dict; | |
} | |
// Modify link hover text | |
function setPMIDlinkTitle(pmid, link_tag) { | |
let pubmed_xml_promise = getPubMedMETAxmlByPMID(pmid); | |
pubmed_xml_promise.then(responseXML => { | |
const docsum_xml = responseXML.getElementsByTagName('DocSum')[0]; | |
const pmd = pmidXML2dict(docsum_xml); | |
const nAuthors = pmd.AuthorList.length; | |
let authorsStr; | |
if (nAuthors > 3) | |
authorsStr = `${pmd.AuthorList[0]}, ... ${pmd.AuthorList[nAuthors - 1]}`; | |
else | |
authorsStr = pmd.AuthorList.join(", "); | |
// Shortened journal name is in .Source, while full name is in .FullJournalName | |
link_tag.title = `${authorsStr}, "${pmd.Title}", ${pmd.Source}, ${pmd.SO}`; | |
}) | |
} | |
// Loop all pmid link nodes and set title | |
function populatePMIDlinkTitles() { | |
let pmid_link_array = document.getElementsByClassName("pmid_link"); | |
for (link_obj of pmid_link_array) { | |
pmid = link_obj.textContent; | |
setPMIDlinkTitle(pmid, link_obj) | |
} | |
} | |
// Open journal in PubmedCentral | |
function openPMCIDJournal(pmcid, html){ | |
var span = document.createElement('span'); | |
span.innerHTML = html; | |
var text = span.innerText; | |
window.open("https://www.ncbi.nlm.nih.gov/pmc/articles/"+pmcid+"#maincontent:~:text="+ encodeURIComponent(text)) | |
} | |
// Expand/collapse all | |
function expandCollapseAll() { | |
let expColBtn = document.getElementById('expand-collapse-all'); | |
let setCss = ''; | |
// Expand all; set ALL_COLLAPSED = false; | |
if (ALL_COLLAPSED) { | |
setCss = 'display: block;'; | |
ALL_COLLAPSED = false; | |
expColBtn.textContent = 'Collapse All'; | |
// Collapse all; set ALL_COLLAPSED = true; | |
} else { | |
setCss = 'display: none;'; | |
ALL_COLLAPSED = true; | |
expColBtn.textContent = 'Expand All'; | |
} | |
// Loop all tags | |
for (tag of document.getElementsByClassName('group')) { | |
tag.style.cssText = setCss | |
} | |
} | |
</script> | |
<style> | |
.source-phosphosite { | |
background-color: #bc80bd; | |
color: black; | |
} | |
.source-cbn { | |
background-color: #fccde5; | |
color: black; | |
} | |
.source-pc11 { | |
background-color: #b3de69; | |
color: black; | |
} | |
.source-biopax { | |
background-color: #80b1d3; | |
color: black; | |
} | |
.source-bel_lc { | |
background-color: #fb8072; | |
color: black; | |
} | |
.source-signor { | |
background-color: #bebada; | |
color: black; | |
} | |
.source-biogrid { | |
background-color: #fdb462; | |
color: black; | |
} | |
.source-tas { | |
background-color: #8dd3c7; | |
color: black; | |
} | |
.source-lincs_drug { | |
background-color: #ffffb3; | |
color: black; | |
} | |
.source-hprd { | |
background-color: #d9d9d9; | |
color: black; | |
} | |
.source-trrust { | |
background-color: #ccebc5; | |
color: black; | |
} | |
.source-geneways { | |
background-color: #bc80bd; | |
color: white; | |
} | |
.source-tees { | |
background-color: #fccde5; | |
color: white; | |
} | |
.source-isi { | |
background-color: #b3de69; | |
color: white; | |
} | |
.source-trips { | |
background-color: #80b1d3; | |
color: white; | |
} | |
.source-rlimsp { | |
background-color: #fb8072; | |
color: white; | |
} | |
.source-medscan { | |
background-color: #bebada; | |
color: white; | |
} | |
.source-sparser { | |
background-color: #fdb462; | |
color: white; | |
} | |
.source-reach { | |
background-color: #8dd3c7; | |
color: white; | |
} | |
.badge-source { | |
font-size: 8pt; | |
margin: 0; | |
} | |
.statements-header { | |
position: -webkit-sticky; | |
position: sticky; | |
top: 0; | |
background-color: white; | |
z-index: 10; | |
padding-top: 5px; | |
} | |
.nvp { | |
padding-left: 0; | |
padding-right: 0; | |
} | |
.src-api { | |
overflow-x: hidden; | |
} | |
.group, .group-shown { | |
padding: 5px; | |
margin: 5px; | |
} | |
.group { | |
display: none; | |
border-left: #0d5aa7 solid 1px; | |
border-right: #0d5aa7 solid 1px; | |
} | |
.super_group_heading, .group_heading, .statement, .evidence { | |
padding: 2px; | |
padding-left: 5px; | |
margin: 2px; | |
position: sticky; | |
border-radius: 2px; | |
} | |
.evidence, .evidence-text { | |
margin-bottom: 10px; | |
} | |
.evidence-text { | |
border-top: #cfcfcf solid 1px; | |
padding-top: 0.5em; | |
} | |
.super_group_heading, .group_heading { | |
cursor: pointer; | |
} | |
.super_group_heading:hover, .group_heading:hover { | |
background-color: #f2f2f2; | |
} | |
.badge-subject { | |
background-color: #4a36aa; | |
color: #FFFFFF; | |
} | |
.badge-object { | |
background-color: #2d8e4c; | |
color: #FFFFFF; | |
} | |
.badge-other { | |
background-color: #606060; | |
color: #FFFFFF; | |
} | |
.curation-row { | |
overflow-y: hidden; | |
} | |
.curation_toggle { | |
cursor: pointer; | |
} | |
.pmid_link, .pmcid_link, .doi_link { | |
display: block; | |
} | |
.full_text_search:hover { | |
text-decoration: underline; | |
} | |
</style> | |
</head> | |
<body> | |
<div class="container"> | |
<!-- Page Header --> | |
<div class="page-header"> | |
<h1>INDRA Results</h1> | |
</div> | |
This page allows you to curate the loaded statements. For more information | |
please see the | |
<a href="https://indra.readthedocs.io/en/latest/tutorials/html_curation.html" | |
target="_blank">manual</a>. | |
<hr> | |
<div class="statements-header"> | |
<div class="row"> | |
<div class="col"> | |
<h3 > | |
Statements | |
</h3> | |
</div> | |
<div class="col text-right"> | |
<button id="expand-collapse-all" type="button" | |
class="btn btn-primary" | |
onclick="expandCollapseAll()"> | |
Expand All | |
</button> | |
</div> | |
</div> | |
<hr> | |
</div> | |
<div class="row super_group_heading" | |
id="tl-37647242-7e59-4309-880d-9f6cc39714f4" | |
onclick="toggler('tl-37647242-7e59-4309-880d-9f6cc39714f4')"> | |
<div class="col nvp"> | |
<h5 class="align-middle"> | |
<a href='https://identifiers.org/chebi/CHEBI:49470' target='_blank'>Aluminium(3+)</a> affects <a href='https://identifiers.org/go/GO:0006955' target='_blank'>immune response</a> | |
</h5> | |
</div> | |
<div class="col text-right nvp"> | |
</div> | |
</div> | |
<div class="group" id="tl-37647242-7e59-4309-880d-9f6cc39714f4_group"> | |
<div class="container nvp"> | |
<div class="row group-shown" id="904d9c54-4ef4-4b7b-a2d0-b01804bd240b_group"> | |
<div class="container nvp"> | |
<a name="-10301112258491834"></a> | |
<div class="row statement"> | |
<div class="col text-left nvp"> | |
<h5 class="align-middle"> | |
<a href='https://identifiers.org/chebi/CHEBI:49470' target='_blank'>Aluminium(3+)</a> activates <a href='https://identifiers.org/go/GO:0006955' target='_blank'>immune response</a>. | |
<a href="#" | |
> | |
<small class="badge badge-secondary badge-pill">1</small> | |
</a> | |
</h5> | |
</div> | |
<div class="col text-right nvp"> | |
</div> | |
</div> | |
<div class="row evidence"> | |
<div class="container" id="stmt-0-0-0" | |
data-stmt_hash="-10301112258491834"> | |
<div class="row evidence-text" data-source_hash="8490993238778999406" | |
style="border-bottom: 1px solid #FFFFFF;" | |
id="ev-0-0-0-0"> | |
<div class="col-1"> | |
<div class="row"> | |
<div class="col-3 nvp curation_toggle" | |
id="ev-0-0-0-0-click" | |
data-parent_id="ev-0-0-0-0"> | |
<a href="#" | |
> | |
➶ | |
</a> | |
</div> | |
<div class="col-9 nvp src-api" | |
title="reach"> | |
reach | |
</div> | |
</div> | |
</div> | |
<div class="col-9"> | |
"We further characterized the <span class="badge badge-object">immune response</span> induced by the formulation that provided the highest protection against invasive lethal challenge and compared it to the <span class="badge badge-object">immune response</span> induced by Combo5 / <span class="badge badge-subject">alum</span> and M1/<span class="badge badge-subject">alum</span>." | |
</div> | |
<div class="col-2 text-right"> | |
<a class="pmid_link" | |
title="Hover again to see info" | |
onmouseover="setPMIDlinkTitle(this.textContent, this); this.onmouseover=null;" | |
href='https://www.ncbi.nlm.nih.gov/pubmed/32156809' | |
target="_blank"> | |
32156809</a> | |
| <a class="pmcid_link full_text_search" | |
onclick='openPMCIDJournal(`PMC7064752`, `We further characterized the <span class="badge badge-object">immune response</span> induced by the formulation that provided the highest protection against invasive lethal challenge and compared it to the <span class="badge badge-object">immune response</span> induced by Combo5 / <span class="badge badge-subject">alum</span> and M1/<span class="badge badge-subject">alum</span>.` );' | |
href="javascript:;">Full-Text Search: PMC7064752</a> | |
</div> | |
</div> | |
</div> <!-- container --> | |
</div> <!-- row evidence --> | |
</div> <!-- PA Statement container --> | |
</div> <!-- PA Statement group --> | |
</div> <!-- container --> | |
</div> <!-- type groups --> | |
<div class="row super_group_heading" | |
id="tl-fe24ee06-4f41-4b6d-918a-6a0d37516186" | |
onclick="toggler('tl-fe24ee06-4f41-4b6d-918a-6a0d37516186')"> | |
<div class="col nvp"> | |
<h5 class="align-middle"> | |
SMQ affects TNF-α | |
</h5> | |
</div> | |
<div class="col text-right nvp"> | |
</div> | |
</div> | |
<div class="group" id="tl-fe24ee06-4f41-4b6d-918a-6a0d37516186_group"> | |
<div class="container nvp"> | |
<div class="row group-shown" id="3260a5fc-2f9c-4b8b-85d3-37da286b05bd_group"> | |
<div class="container nvp"> | |
<a name="-25651963520341412"></a> | |
<div class="row statement"> | |
<div class="col text-left nvp"> | |
<h5 class="align-middle"> | |
SMQ activates TNF-α. | |
<a href="#" | |
> | |
<small class="badge badge-secondary badge-pill">1</small> | |
</a> | |
</h5> | |
</div> | |
<div class="col text-right nvp"> | |
</div> | |
</div> | |
<div class="row evidence"> | |
<div class="container" id="stmt-1-0-0" | |
data-stmt_hash="-25651963520341412"> | |
<div class="row evidence-text" data-source_hash="4155885927386739680" | |
style="border-bottom: 1px solid #FFFFFF;" | |
id="ev-1-0-0-0"> | |
<div class="col-1"> | |
<div class="row"> | |
<div class="col-3 nvp curation_toggle" | |
id="ev-1-0-0-0-click" | |
data-parent_id="ev-1-0-0-0"> | |
<a href="#" | |
> | |
➶ | |
</a> | |
</div> | |
<div class="col-9 nvp src-api" | |
title="reach"> | |
reach | |
</div> | |
</div> | |
</div> | |
<div class="col-9"> | |
"A comparison between the cytokine concentrations secreted by splenocytes from Combo5 / alum and Combo5 / <span class="badge badge-subject">SMQ</span> immune mice showed that the <span class="badge badge-subject">SMQ</span> adjuvanted formulation induced significantly higher secretion of IL-6, IL-10, IFN-γ, and <span class="badge badge-object">TNF-α</span> than the alum adjuvanted formulation." | |
</div> | |
<div class="col-2 text-right"> | |
<a class="pmid_link" | |
title="Hover again to see info" | |
onmouseover="setPMIDlinkTitle(this.textContent, this); this.onmouseover=null;" | |
href='https://www.ncbi.nlm.nih.gov/pubmed/32156809' | |
target="_blank"> | |
32156809</a> | |
| <a class="pmcid_link full_text_search" | |
onclick='openPMCIDJournal(`PMC7064752`, `A comparison between the cytokine concentrations secreted by splenocytes from Combo5 / alum and Combo5 / <span class="badge badge-subject">SMQ</span> immune mice showed that the <span class="badge badge-subject">SMQ</span> adjuvanted formulation induced significantly higher secretion of IL-6, IL-10, IFN-γ, and <span class="badge badge-object">TNF-α</span> than the alum adjuvanted formulation.` );' | |
href="javascript:;">Full-Text Search: PMC7064752</a> | |
</div> | |
</div> | |
</div> <!-- container --> | |
</div> <!-- row evidence --> | |
</div> <!-- PA Statement container --> | |
</div> <!-- PA Statement group --> | |
</div> <!-- container --> | |
</div> <!-- type groups --> | |
<div class="row super_group_heading" | |
id="tl-d5196a9b-4c5e-4d13-813b-2a262c6a1801" | |
onclick="toggler('tl-d5196a9b-4c5e-4d13-813b-2a262c6a1801')"> | |
<div class="col nvp"> | |
<h5 class="align-middle"> | |
SMQ affects <a href='https://identifiers.org/hgnc/HGNC:6018' target='_blank'>IL6</a> | |
</h5> | |
</div> | |
<div class="col text-right nvp"> | |
</div> | |
</div> | |
<div class="group" id="tl-d5196a9b-4c5e-4d13-813b-2a262c6a1801_group"> | |
<div class="container nvp"> | |
<div class="row group-shown" id="d2e4c2d0-edea-4418-83dc-3bb7349d6622_group"> | |
<div class="container nvp"> | |
<a name="-17919606370707517"></a> | |
<div class="row statement"> | |
<div class="col text-left nvp"> | |
<h5 class="align-middle"> | |
SMQ activates <a href='https://identifiers.org/hgnc/HGNC:6018' target='_blank'>IL6</a>. | |
<a href="#" | |
> | |
<small class="badge badge-secondary badge-pill">1</small> | |
</a> | |
</h5> | |
</div> | |
<div class="col text-right nvp"> | |
</div> | |
</div> | |
<div class="row evidence"> | |
<div class="container" id="stmt-2-0-0" | |
data-stmt_hash="-17919606370707517"> | |
<div class="row evidence-text" data-source_hash="4155885927386739680" | |
style="border-bottom: 1px solid #FFFFFF;" | |
id="ev-2-0-0-0"> | |
<div class="col-1"> | |
<div class="row"> | |
<div class="col-3 nvp curation_toggle" | |
id="ev-2-0-0-0-click" | |
data-parent_id="ev-2-0-0-0"> | |
<a href="#" | |
> | |
➶ | |
</a> | |
</div> | |
<div class="col-9 nvp src-api" | |
title="reach"> | |
reach | |
</div> | |
</div> | |
</div> | |
<div class="col-9"> | |
"A comparison between the cytokine concentrations secreted by splenocytes from Combo5 / alum and Combo5 / <span class="badge badge-subject">SMQ</span> immune mice showed that the <span class="badge badge-subject">SMQ</span> adjuvanted formulation induced significantly higher secretion of <span class="badge badge-object">IL-6</span>, IL-10, IFN-γ, and TNF-α than the alum adjuvanted formulation." | |
</div> | |
<div class="col-2 text-right"> | |
<a class="pmid_link" | |
title="Hover again to see info" | |
onmouseover="setPMIDlinkTitle(this.textContent, this); this.onmouseover=null;" | |
href='https://www.ncbi.nlm.nih.gov/pubmed/32156809' | |
target="_blank"> | |
32156809</a> | |
| <a class="pmcid_link full_text_search" | |
onclick='openPMCIDJournal(`PMC7064752`, `A comparison between the cytokine concentrations secreted by splenocytes from Combo5 / alum and Combo5 / <span class="badge badge-subject">SMQ</span> immune mice showed that the <span class="badge badge-subject">SMQ</span> adjuvanted formulation induced significantly higher secretion of <span class="badge badge-object">IL-6</span>, IL-10, IFN-γ, and TNF-α than the alum adjuvanted formulation.` );' | |
href="javascript:;">Full-Text Search: PMC7064752</a> | |
</div> | |
</div> | |
</div> <!-- container --> | |
</div> <!-- row evidence --> | |
</div> <!-- PA Statement container --> | |
</div> <!-- PA Statement group --> | |
</div> <!-- container --> | |
</div> <!-- type groups --> | |
<div class="row super_group_heading" | |
id="tl-3c759c4a-d031-42b0-9f67-5f9fe8fe0827" | |
onclick="toggler('tl-3c759c4a-d031-42b0-9f67-5f9fe8fe0827')"> | |
<div class="col nvp"> | |
<h5 class="align-middle"> | |
SMQ affects <a href='https://identifiers.org/hgnc/HGNC:5962' target='_blank'>IL10</a> | |
</h5> | |
</div> | |
<div class="col text-right nvp"> | |
</div> | |
</div> | |
<div class="group" id="tl-3c759c4a-d031-42b0-9f67-5f9fe8fe0827_group"> | |
<div class="container nvp"> | |
<div class="row group-shown" id="ba1a9b42-32e5-4069-95c4-599248fb18fc_group"> | |
<div class="container nvp"> | |
<a name="30554384213470801"></a> | |
<div class="row statement"> | |
<div class="col text-left nvp"> | |
<h5 class="align-middle"> | |
SMQ activates <a href='https://identifiers.org/hgnc/HGNC:5962' target='_blank'>IL10</a>. | |
<a href="#" | |
> | |
<small class="badge badge-secondary badge-pill">1</small> | |
</a> | |
</h5> | |
</div> | |
<div class="col text-right nvp"> | |
</div> | |
</div> | |
<div class="row evidence"> | |
<div class="container" id="stmt-3-0-0" | |
data-stmt_hash="30554384213470801"> | |
<div class="row evidence-text" data-source_hash="4155885927386739680" | |
style="border-bottom: 1px solid #FFFFFF;" | |
id="ev-3-0-0-0"> | |
<div class="col-1"> | |
<div class="row"> | |
<div class="col-3 nvp curation_toggle" | |
id="ev-3-0-0-0-click" | |
data-parent_id="ev-3-0-0-0"> | |
<a href="#" | |
> | |
➶ | |
</a> | |
</div> | |
<div class="col-9 nvp src-api" | |
title="reach"> | |
reach | |
</div> | |
</div> | |
</div> | |
<div class="col-9"> | |
"A comparison between the cytokine concentrations secreted by splenocytes from Combo5 / alum and Combo5 / <span class="badge badge-subject">SMQ</span> immune mice showed that the <span class="badge badge-subject">SMQ</span> adjuvanted formulation induced significantly higher secretion of IL-6, <span class="badge badge-object">IL-10</span>, IFN-γ, and TNF-α than the alum adjuvanted formulation." | |
</div> | |
<div class="col-2 text-right"> | |
<a class="pmid_link" | |
title="Hover again to see info" | |
onmouseover="setPMIDlinkTitle(this.textContent, this); this.onmouseover=null;" | |
href='https://www.ncbi.nlm.nih.gov/pubmed/32156809' | |
target="_blank"> | |
32156809</a> | |
| <a class="pmcid_link full_text_search" | |
onclick='openPMCIDJournal(`PMC7064752`, `A comparison between the cytokine concentrations secreted by splenocytes from Combo5 / alum and Combo5 / <span class="badge badge-subject">SMQ</span> immune mice showed that the <span class="badge badge-subject">SMQ</span> adjuvanted formulation induced significantly higher secretion of IL-6, <span class="badge badge-object">IL-10</span>, IFN-γ, and TNF-α than the alum adjuvanted formulation.` );' | |
href="javascript:;">Full-Text Search: PMC7064752</a> | |
</div> | |
</div> | |
</div> <!-- container --> | |
</div> <!-- row evidence --> | |
</div> <!-- PA Statement container --> | |
</div> <!-- PA Statement group --> | |
</div> <!-- container --> | |
</div> <!-- type groups --> | |
<div class="row super_group_heading" | |
id="tl-9f6196e4-7d73-4e47-826b-1d2649d1fd03" | |
onclick="toggler('tl-9f6196e4-7d73-4e47-826b-1d2649d1fd03')"> | |
<div class="col nvp"> | |
<h5 class="align-middle"> | |
SMQ affects IFN-γ | |
</h5> | |
</div> | |
<div class="col text-right nvp"> | |
</div> | |
</div> | |
<div class="group" id="tl-9f6196e4-7d73-4e47-826b-1d2649d1fd03_group"> | |
<div class="container nvp"> | |
<div class="row group-shown" id="3b9e1ee8-2a64-4acb-9407-0081f84a656a_group"> | |
<div class="container nvp"> | |
<a name="13465087121692280"></a> | |
<div class="row statement"> | |
<div class="col text-left nvp"> | |
<h5 class="align-middle"> | |
SMQ activates IFN-γ. | |
<a href="#" | |
> | |
<small class="badge badge-secondary badge-pill">1</small> | |
</a> | |
</h5> | |
</div> | |
<div class="col text-right nvp"> | |
</div> | |
</div> | |
<div class="row evidence"> | |
<div class="container" id="stmt-4-0-0" | |
data-stmt_hash="13465087121692280"> | |
<div class="row evidence-text" data-source_hash="4155885927386739680" | |
style="border-bottom: 1px solid #FFFFFF;" | |
id="ev-4-0-0-0"> | |
<div class="col-1"> | |
<div class="row"> | |
<div class="col-3 nvp curation_toggle" | |
id="ev-4-0-0-0-click" | |
data-parent_id="ev-4-0-0-0"> | |
<a href="#" | |
> | |
➶ | |
</a> | |
</div> | |
<div class="col-9 nvp src-api" | |
title="reach"> | |
reach | |
</div> | |
</div> | |
</div> | |
<div class="col-9"> | |
"A comparison between the cytokine concentrations secreted by splenocytes from Combo5 / alum and Combo5 / <span class="badge badge-subject">SMQ</span> immune mice showed that the <span class="badge badge-subject">SMQ</span> adjuvanted formulation induced significantly higher secretion of IL-6, IL-10, <span class="badge badge-object">IFN-γ</span>, and TNF-α than the alum adjuvanted formulation." | |
</div> | |
<div class="col-2 text-right"> | |
<a class="pmid_link" | |
title="Hover again to see info" | |
onmouseover="setPMIDlinkTitle(this.textContent, this); this.onmouseover=null;" | |
href='https://www.ncbi.nlm.nih.gov/pubmed/32156809' | |
target="_blank"> | |
32156809</a> | |
| <a class="pmcid_link full_text_search" | |
onclick='openPMCIDJournal(`PMC7064752`, `A comparison between the cytokine concentrations secreted by splenocytes from Combo5 / alum and Combo5 / <span class="badge badge-subject">SMQ</span> immune mice showed that the <span class="badge badge-subject">SMQ</span> adjuvanted formulation induced significantly higher secretion of IL-6, IL-10, <span class="badge badge-object">IFN-γ</span>, and TNF-α than the alum adjuvanted formulation.` );' | |
href="javascript:;">Full-Text Search: PMC7064752</a> | |
</div> | |
</div> | |
</div> <!-- container --> | |
</div> <!-- row evidence --> | |
</div> <!-- PA Statement container --> | |
</div> <!-- PA Statement group --> | |
</div> <!-- container --> | |
</div> <!-- type groups --> | |
<div class="row super_group_heading" | |
id="tl-e7c84fd6-4341-4cdf-af52-4d53ea2cd73f" | |
onclick="toggler('tl-e7c84fd6-4341-4cdf-af52-4d53ea2cd73f')"> | |
<div class="col nvp"> | |
<h5 class="align-middle"> | |
<a href='https://identifiers.org/chebi/CHEBI:51079' target='_blank'>GS26575</a> affects <a href='https://identifiers.org/hgnc/HGNC:4164' target='_blank'>GAST</a> | |
</h5> | |
</div> | |
<div class="col text-right nvp"> | |
</div> | |
</div> | |
<div class="group" id="tl-e7c84fd6-4341-4cdf-af52-4d53ea2cd73f_group"> | |
<div class="container nvp"> | |
<div class="row group-shown" id="9cf74aef-9073-41b0-895d-51655ee916f8_group"> | |
<div class="container nvp"> | |
<a name="-31029788656818151"></a> | |
<div class="row statement"> | |
<div class="col text-left nvp"> | |
<h5 class="align-middle"> | |
<a href='https://identifiers.org/chebi/CHEBI:51079' target='_blank'>GS26575</a> activates <a href='https://identifiers.org/hgnc/HGNC:4164' target='_blank'>GAST</a>. | |
<a href="#" | |
> | |
<small class="badge badge-secondary badge-pill">1</small> | |
</a> | |
</h5> | |
</div> | |
<div class="col text-right nvp"> | |
</div> | |
</div> | |
<div class="row evidence"> | |
<div class="container" id="stmt-5-0-0" | |
data-stmt_hash="-31029788656818151"> | |
<div class="row evidence-text" data-source_hash="-5164385967986893407" | |
style="border-bottom: 1px solid #FFFFFF;" | |
id="ev-5-0-0-0"> | |
<div class="col-1"> | |
<div class="row"> | |
<div class="col-3 nvp curation_toggle" | |
id="ev-5-0-0-0-click" | |
data-parent_id="ev-5-0-0-0"> | |
<a href="#" | |
> | |
➶ | |
</a> | |
</div> | |
<div class="col-9 nvp src-api" | |
title="reach"> | |
reach | |
</div> | |
</div> | |
</div> | |
<div class="col-9"> | |
"Only <span class="badge badge-subject">M1</span> immune sera was able to promote opsonophagocytic killing of <span class="badge badge-object">GAS</span> (XREF_FIG) with an opsonic index significantly higher than that measured for naive mice." | |
</div> | |
<div class="col-2 text-right"> | |
<a class="pmid_link" | |
title="Hover again to see info" | |
onmouseover="setPMIDlinkTitle(this.textContent, this); this.onmouseover=null;" | |
href='https://www.ncbi.nlm.nih.gov/pubmed/32156809' | |
target="_blank"> | |
32156809</a> | |
| <a class="pmcid_link full_text_search" | |
onclick='openPMCIDJournal(`PMC7064752`, `Only <span class="badge badge-subject">M1</span> immune sera was able to promote opsonophagocytic killing of <span class="badge badge-object">GAS</span> (XREF_FIG) with an opsonic index significantly higher than that measured for naive mice.` );' | |
href="javascript:;">Full-Text Search: PMC7064752</a> | |
</div> | |
</div> | |
</div> <!-- container --> | |
</div> <!-- row evidence --> | |
</div> <!-- PA Statement container --> | |
</div> <!-- PA Statement group --> | |
</div> <!-- container --> | |
</div> <!-- type groups --> | |
<div class="row super_group_heading" | |
id="tl-764b485b-d8f0-4df9-b48b-16e5cdf28b55" | |
onclick="toggler('tl-764b485b-d8f0-4df9-b48b-16e5cdf28b55')"> | |
<div class="col nvp"> | |
<h5 class="align-middle"> | |
Combo5 affects <a href='https://identifiers.org/go/GO:0006955' target='_blank'>immune response</a> | |
</h5> | |
</div> | |
<div class="col text-right nvp"> | |
</div> | |
</div> | |
<div class="group" id="tl-764b485b-d8f0-4df9-b48b-16e5cdf28b55_group"> | |
<div class="container nvp"> | |
<div class="row group-shown" id="471570d0-b7a7-4a22-9bd4-f931d4f1afbe_group"> | |
<div class="container nvp"> | |
<a name="-12695682573761343"></a> | |
<div class="row statement"> | |
<div class="col text-left nvp"> | |
<h5 class="align-middle"> | |
Combo5 activates <a href='https://identifiers.org/go/GO:0006955' target='_blank'>immune response</a>. | |
<a href="#" | |
> | |
<small class="badge badge-secondary badge-pill">1</small> | |
</a> | |
</h5> | |
</div> | |
<div class="col text-right nvp"> | |
</div> | |
</div> | |
<div class="row evidence"> | |
<div class="container" id="stmt-6-0-0" | |
data-stmt_hash="-12695682573761343"> | |
<div class="row evidence-text" data-source_hash="597975201937205239" | |
style="border-bottom: 1px solid #FFFFFF;" | |
id="ev-6-0-0-0"> | |
<div class="col-1"> | |
<div class="row"> | |
<div class="col-3 nvp curation_toggle" | |
id="ev-6-0-0-0-click" | |
data-parent_id="ev-6-0-0-0"> | |
<a href="#" | |
> | |
➶ | |
</a> | |
</div> | |
<div class="col-9 nvp src-api" | |
title="reach"> | |
reach | |
</div> | |
</div> | |
</div> | |
<div class="col-9"> | |
"We further characterized the protective <span class="badge badge-object">immune response</span> elicited by <span class="badge badge-subject">Combo5</span> formulated with SMQ adjuvant and compared this to the nonprotective response elicited by <span class="badge badge-subject">Combo5</span> / alum and to the protective response elicited by the “ gold standard ” homologous M1 protein formulated with alum." | |
</div> | |
<div class="col-2 text-right"> | |
<a class="pmid_link" | |
title="Hover again to see info" | |
onmouseover="setPMIDlinkTitle(this.textContent, this); this.onmouseover=null;" | |
href='https://www.ncbi.nlm.nih.gov/pubmed/32156809' | |
target="_blank"> | |
32156809</a> | |
| <a class="pmcid_link full_text_search" | |
onclick='openPMCIDJournal(`PMC7064752`, `We further characterized the protective <span class="badge badge-object">immune response</span> elicited by <span class="badge badge-subject">Combo5</span> formulated with SMQ adjuvant and compared this to the nonprotective response elicited by <span class="badge badge-subject">Combo5</span> / alum and to the protective response elicited by the “ gold standard ” homologous M1 protein formulated with alum.` );' | |
href="javascript:;">Full-Text Search: PMC7064752</a> | |
</div> | |
</div> | |
</div> <!-- container --> | |
</div> <!-- row evidence --> | |
</div> <!-- PA Statement container --> | |
</div> <!-- PA Statement group --> | |
</div> <!-- container --> | |
</div> <!-- type groups --> | |
<hr> | |
<!-- Footer --> | |
<footer class="footer text-muted" id="about"> | |
<h5 class="my-0 mr-md-auto font-weight-normal">About</h5> | |
INDRA is developed by <a href="https://indralab.github.io/">indralabs</a>, | |
a part of the Harvard Medical School Laboratory of Systems Pharmacology. | |
</footer> | |
</div> | |
</body> | |
</html> |
This file contains bidirectional Unicode text that may be interpreted or compiled differently than what appears below. To review, open the file in an editor that reveals hidden Unicode characters.
Learn more about bidirectional Unicode characters
import json | |
from indra.sources import reach, trips | |
from indra.statements.statements import stmts_to_json | |
from indra.assemblers.html.assembler import HtmlAssembler | |
from indra.assemblers.english.assembler import EnglishAssembler | |
from indra.assemblers.tsv.assembler import TsvAssembler | |
ha = HtmlAssembler() | |
reach_processor_2 = reach.api.process_pmc("7064752") | |
stmts = reach_processor_2.statements | |
ha.add_statements(stmts) | |
html = ha.make_model(template=None, with_grouping=True, add_full_text_search_link=True) | |
ha.save_model('output.html') |
Sign up for free
to join this conversation on GitHub.
Already have an account?
Sign in to comment