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| <!DOCTYPE html> | |
| <html lang="en"> | |
| <head> | |
| <meta charset="utf-8"> | |
| <meta http-equiv="X-UA-Compatible" content="IE=edge"> | |
| <meta name="viewport" content="width=device-width, initial-scale=1"> | |
| <!-- The above 3 meta tags *must* come first in the head; any other head content must come *after* these tags --> | |
| <meta name="description" content=""> | |
| <meta name="author" content=""> | |
| <link rel="icon" href="https://bigmech.s3.amazonaws.com/indra-db/favicon.ico"> | |
| <title>INDRA Results</title> | |
| <script src="https://code.jquery.com/jquery-3.3.1.min.js" | |
| integrity="sha256-FgpCb/KJQlLNfOu91ta32o/NMZxltwRo8QtmkMRdAu8=" | |
| crossorigin="anonymous"></script> | |
| <!-- Latest compiled and minified CSS --> | |
| <link rel="stylesheet" | |
| href="https://stackpath.bootstrapcdn.com/bootstrap/4.1.3/css/bootstrap.min.css" | |
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| crossorigin="anonymous"> | |
| <!-- Optional theme --> | |
| <link rel="stylesheet" | |
| href="https://use.fontawesome.com/releases/v5.5.0/css/all.css" | |
| integrity="sha384-B4dIYHKNBt8Bc12p+WXckhzcICo0wtJAoU8YZTY5qE0Id1GSseTk6S+L3BlXeVIU" | |
| crossorigin="anonymous"> | |
| <!-- Latest compiled and minified JavaScript --> | |
| <script src="https://stackpath.bootstrapcdn.com/bootstrap/4.1.3/js/bootstrap.min.js" | |
| integrity="sha384-ChfqqxuZUCnJSK3+MXmPNIyE6ZbWh2IMqE241rYiqJxyMiZ6OW/JmZQ5stwEULTy" | |
| crossorigin="anonymous"></script> | |
| <style> | |
| a { | |
| color: #256DC5; | |
| target-new: tab; | |
| } | |
| h1 { | |
| margin-bottom: 0; | |
| } | |
| .page-header { | |
| padding: 1em; | |
| } | |
| </style> | |
| <!-- Toggle a hidden element --> | |
| <script> | |
| const pubmed_fetch = "https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi"; | |
| let ALL_COLLAPSED = true; | |
| function toggler(short_name_key) { | |
| $("#" + short_name_key + "_group").toggle(); | |
| let header = "#" + short_name_key + "_heading"; | |
| $(header).show(); | |
| } | |
| function getPubMedMETAxmlByPMID(pmid) { | |
| let params_dict = { | |
| 'db': 'pubmed', | |
| 'retmode': 'xml', | |
| 'rettype': 'docsum', | |
| 'id': pmid | |
| }; | |
| return $.ajax({ | |
| url: pubmed_fetch, | |
| type: "POST", | |
| dataType: "xml", | |
| data: params_dict, | |
| }); | |
| } | |
| function pmidXML2dict(XML) { | |
| let xml_dict = {}; | |
| for (let child of XML.children) { | |
| let name = child.getAttribute("Name"); | |
| let type = child.getAttribute("Type"); | |
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| // Javascript can't really do nice recursive functions... | |
| // special cases for "History" and "ArticleIds" which has unique inner Names | |
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| } | |
| } | |
| } | |
| return xml_dict; | |
| } | |
| // Modify link hover text | |
| function setPMIDlinkTitle(pmid, link_tag) { | |
| let pubmed_xml_promise = getPubMedMETAxmlByPMID(pmid); | |
| pubmed_xml_promise.then(responseXML => { | |
| const docsum_xml = responseXML.getElementsByTagName('DocSum')[0]; | |
| const pmd = pmidXML2dict(docsum_xml); | |
| const nAuthors = pmd.AuthorList.length; | |
| let authorsStr; | |
| if (nAuthors > 3) | |
| authorsStr = `${pmd.AuthorList[0]}, ... ${pmd.AuthorList[nAuthors - 1]}`; | |
| else | |
| authorsStr = pmd.AuthorList.join(", "); | |
| // Shortened journal name is in .Source, while full name is in .FullJournalName | |
| link_tag.title = `${authorsStr}, "${pmd.Title}", ${pmd.Source}, ${pmd.SO}`; | |
| }) | |
| } | |
| // Loop all pmid link nodes and set title | |
| function populatePMIDlinkTitles() { | |
| let pmid_link_array = document.getElementsByClassName("pmid_link"); | |
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| pmid = link_obj.textContent; | |
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| lastWord = lastWord.substring(0,lastWord.length-1) | |
| searchText += "," + encodeURIComponent(secondLastWord + lastWord); | |
| } | |
| element.href += "#:~:text="+ searchText.trim() | |
| } | |
| }; | |
| </script> | |
| <style> | |
| .source-phosphosite { | |
| background-color: #bc80bd; | |
| color: black; | |
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| .source-cbn { | |
| background-color: #fccde5; | |
| color: black; | |
| } | |
| .source-pc11 { | |
| background-color: #b3de69; | |
| color: black; | |
| } | |
| .source-biopax { | |
| background-color: #80b1d3; | |
| color: black; | |
| } | |
| .source-bel_lc { | |
| background-color: #fb8072; | |
| color: black; | |
| } | |
| .source-signor { | |
| background-color: #bebada; | |
| color: black; | |
| } | |
| .source-biogrid { | |
| background-color: #fdb462; | |
| color: black; | |
| } | |
| .source-tas { | |
| background-color: #8dd3c7; | |
| color: black; | |
| } | |
| .source-lincs_drug { | |
| background-color: #ffffb3; | |
| color: black; | |
| } | |
| .source-hprd { | |
| background-color: #d9d9d9; | |
| color: black; | |
| } | |
| .source-trrust { | |
| background-color: #ccebc5; | |
| color: black; | |
| } | |
| .source-geneways { | |
| background-color: #bc80bd; | |
| color: white; | |
| } | |
| .source-tees { | |
| background-color: #fccde5; | |
| color: white; | |
| } | |
| .source-isi { | |
| background-color: #b3de69; | |
| color: white; | |
| } | |
| .source-trips { | |
| background-color: #80b1d3; | |
| color: white; | |
| } | |
| .source-rlimsp { | |
| background-color: #fb8072; | |
| color: white; | |
| } | |
| .source-medscan { | |
| background-color: #bebada; | |
| color: white; | |
| } | |
| .source-sparser { | |
| background-color: #fdb462; | |
| color: white; | |
| } | |
| .source-reach { | |
| background-color: #8dd3c7; | |
| color: white; | |
| } | |
| .badge-source { | |
| font-size: 8pt; | |
| margin: 0; | |
| } | |
| .statements-header { | |
| position: -webkit-sticky; | |
| position: sticky; | |
| top: 0; | |
| background-color: white; | |
| z-index: 10; | |
| padding-top: 5px; | |
| } | |
| .nvp { | |
| padding-left: 0; | |
| padding-right: 0; | |
| } | |
| .src-api { | |
| overflow-x: hidden; | |
| } | |
| .group, .group-shown { | |
| padding: 5px; | |
| margin: 5px; | |
| } | |
| .group { | |
| display: none; | |
| border-left: #0d5aa7 solid 1px; | |
| border-right: #0d5aa7 solid 1px; | |
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| .super_group_heading, .group_heading, .statement, .evidence { | |
| padding: 2px; | |
| padding-left: 5px; | |
| margin: 2px; | |
| position: sticky; | |
| border-radius: 2px; | |
| } | |
| .evidence, .evidence-text { | |
| margin-bottom: 10px; | |
| } | |
| .evidence-text { | |
| border-top: #cfcfcf solid 1px; | |
| padding-top: 0.5em; | |
| } | |
| .super_group_heading, .group_heading { | |
| cursor: pointer; | |
| } | |
| .super_group_heading:hover, .group_heading:hover { | |
| background-color: #f2f2f2; | |
| } | |
| .badge-subject { | |
| background-color: #4a36aa; | |
| color: #FFFFFF; | |
| } | |
| .badge-object { | |
| background-color: #2d8e4c; | |
| color: #FFFFFF; | |
| } | |
| .badge-other { | |
| background-color: #606060; | |
| color: #FFFFFF; | |
| } | |
| .curation-row { | |
| overflow-y: hidden; | |
| } | |
| .curation_toggle { | |
| cursor: pointer; | |
| } | |
| .pmid_link, .pmcid_link, .doi_link { | |
| display: block; | |
| } | |
| </style> | |
| </head> | |
| <body> | |
| <div class="container"> | |
| <!-- Page Header --> | |
| <div class="page-header"> | |
| <h1>INDRA Results</h1> | |
| </div> | |
| This page allows you to curate the loaded statements. For more information | |
| please see the | |
| <a href="https://indra.readthedocs.io/en/latest/tutorials/html_curation.html" | |
| target="_blank">manual</a>. | |
| <hr> | |
| <div class="statements-header"> | |
| <div class="row"> | |
| <div class="col"> | |
| <h3 > | |
| Statements | |
| </h3> | |
| </div> | |
| <div class="col text-right"> | |
| <button id="expand-collapse-all" type="button" | |
| class="btn btn-primary" | |
| onclick="expandCollapseAll()"> | |
| Expand All | |
| </button> | |
| </div> | |
| </div> | |
| <hr> | |
| </div> | |
| <div class="group-shown" id="tl-c1d46af7-9aa2-42ff-9396-e7f652f5fc38_group"> | |
| <div class="container nvp"> | |
| <div class="row group-shown" id="all-statements-sub-group_group"> | |
| <div class="container nvp"> | |
| <a name="-10301112258491834"></a> | |
| <div class="row statement"> | |
| <div class="col text-left nvp"> | |
| <h5 class="align-middle"> | |
| <a href='https://identifiers.org/chebi/CHEBI:49470' target='_blank'>Aluminium(3+)</a> activates <a href='https://identifiers.org/go/GO:0006955' target='_blank'>immune response</a>. | |
| <a href="#" | |
| > | |
| <small class="badge badge-secondary badge-pill">1</small> | |
| </a> | |
| </h5> | |
| </div> | |
| <div class="col text-right nvp"> | |
| </div> | |
| </div> | |
| <div class="row evidence"> | |
| <div class="container" id="stmt-0-0-0" | |
| data-stmt_hash="-10301112258491834"> | |
| <div class="row evidence-text" data-source_hash="8490993238778999406" | |
| style="border-bottom: 1px solid #FFFFFF;" | |
| id="ev-0-0-0-0"> | |
| <div class="col-1"> | |
| <div class="row"> | |
| <div class="col-3 nvp curation_toggle" | |
| id="ev-0-0-0-0-click" | |
| data-parent_id="ev-0-0-0-0"> | |
| <a href="#" | |
| > | |
| ➶ | |
| </a> | |
| </div> | |
| <div class="col-9 nvp src-api" | |
| title="reach"> | |
| reach | |
| </div> | |
| </div> | |
| </div> | |
| <div class="col-9"> | |
| "We further characterized the <span class="badge badge-object">immune response</span> induced by the formulation that provided the highest protection against invasive lethal challenge and compared it to the <span class="badge badge-object">immune response</span> induced by Combo5 / <span class="badge badge-subject">alum</span> and M1/<span class="badge badge-subject">alum</span>." | |
| </div> | |
| <div class="col-2 text-right"> | |
| <a class="pmid_link" | |
| title="Hover again to see info" | |
| onmouseover="setPMIDlinkTitle(this.textContent, this); this.onmouseover=null;" | |
| href='https://www.ncbi.nlm.nih.gov/pubmed/32156809' | |
| target="_blank"> | |
| 32156809</a> | |
| <a class="full_text_search" | |
| data-sentence= 'We%20further%20characterized%20the%20%3Cspan%20class%3D%22badge%20badge-object%22%3Eimmune%20response%3C/span%3E%20induced%20by%20the%20formulation%20that%20provided%20the%20highest%20protection%20against%20invasive%20lethal%20challenge%20and%20compared%20it%20to%20the%20%3Cspan%20class%3D%22badge%20badge-object%22%3Eimmune%20response%3C/span%3E%20induced%20by%20Combo5%20/%20%3Cspan%20class%3D%22badge%20badge-subject%22%3Ealum%3C/span%3E%20and%20M1/%3Cspan%20class%3D%22badge%20badge-subject%22%3Ealum%3C/span%3E.' | |
| href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7064752" target=_blank rel=noopener >Full-Text Search: PMC7064752</a> | |
| <span style="cursor:default" title="This link will search for and highlight the sentence in the full-text article. Works with Chrome 80+"> ⓘ</span> | |
| </div> | |
| </div> | |
| </div> <!-- container --> | |
| </div> <!-- row evidence --> | |
| <a name="-25651963520341412"></a> | |
| <div class="row statement"> | |
| <div class="col text-left nvp"> | |
| <h5 class="align-middle"> | |
| SMQ activates TNF-α. | |
| <a href="#" | |
| > | |
| <small class="badge badge-secondary badge-pill">1</small> | |
| </a> | |
| </h5> | |
| </div> | |
| <div class="col text-right nvp"> | |
| </div> | |
| </div> | |
| <div class="row evidence"> | |
| <div class="container" id="stmt-0-0-1" | |
| data-stmt_hash="-25651963520341412"> | |
| <div class="row evidence-text" data-source_hash="4155885927386739680" | |
| style="border-bottom: 1px solid #FFFFFF;" | |
| id="ev-0-0-1-0"> | |
| <div class="col-1"> | |
| <div class="row"> | |
| <div class="col-3 nvp curation_toggle" | |
| id="ev-0-0-1-0-click" | |
| data-parent_id="ev-0-0-1-0"> | |
| <a href="#" | |
| > | |
| ➶ | |
| </a> | |
| </div> | |
| <div class="col-9 nvp src-api" | |
| title="reach"> | |
| reach | |
| </div> | |
| </div> | |
| </div> | |
| <div class="col-9"> | |
| "A comparison between the cytokine concentrations secreted by splenocytes from Combo5 / alum and Combo5 / <span class="badge badge-subject">SMQ</span> immune mice showed that the <span class="badge badge-subject">SMQ</span> adjuvanted formulation induced significantly higher secretion of IL-6, IL-10, IFN-γ, and <span class="badge badge-object">TNF-α</span> than the alum adjuvanted formulation." | |
| </div> | |
| <div class="col-2 text-right"> | |
| <a class="pmid_link" | |
| title="Hover again to see info" | |
| onmouseover="setPMIDlinkTitle(this.textContent, this); this.onmouseover=null;" | |
| href='https://www.ncbi.nlm.nih.gov/pubmed/32156809' | |
| target="_blank"> | |
| 32156809</a> | |
| <a class="full_text_search" | |
| data-sentence= 'A%20comparison%20between%20the%20cytokine%20concentrations%20secreted%20by%20splenocytes%20from%20Combo5%20/%20alum%20and%20Combo5%20/%20%3Cspan%20class%3D%22badge%20badge-subject%22%3ESMQ%3C/span%3E%20immune%20mice%20showed%20that%20the%20%3Cspan%20class%3D%22badge%20badge-subject%22%3ESMQ%3C/span%3E%20adjuvanted%20formulation%20induced%20significantly%20higher%20secretion%20of%20IL-6%2C%20IL-10%2C%20IFN-%CE%B3%2C%20and%20%3Cspan%20class%3D%22badge%20badge-object%22%3ETNF-%CE%B1%3C/span%3E%20than%20the%20alum%20adjuvanted%20formulation.' | |
| href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7064752" target=_blank rel=noopener >Full-Text Search: PMC7064752</a> | |
| <span style="cursor:default" title="This link will search for and highlight the sentence in the full-text article. Works with Chrome 80+"> ⓘ</span> | |
| </div> | |
| </div> | |
| </div> <!-- container --> | |
| </div> <!-- row evidence --> | |
| <a name="-17919606370707517"></a> | |
| <div class="row statement"> | |
| <div class="col text-left nvp"> | |
| <h5 class="align-middle"> | |
| SMQ activates <a href='https://identifiers.org/hgnc/HGNC:6018' target='_blank'>IL6</a>. | |
| <a href="#" | |
| > | |
| <small class="badge badge-secondary badge-pill">1</small> | |
| </a> | |
| </h5> | |
| </div> | |
| <div class="col text-right nvp"> | |
| </div> | |
| </div> | |
| <div class="row evidence"> | |
| <div class="container" id="stmt-0-0-2" | |
| data-stmt_hash="-17919606370707517"> | |
| <div class="row evidence-text" data-source_hash="4155885927386739680" | |
| style="border-bottom: 1px solid #FFFFFF;" | |
| id="ev-0-0-2-0"> | |
| <div class="col-1"> | |
| <div class="row"> | |
| <div class="col-3 nvp curation_toggle" | |
| id="ev-0-0-2-0-click" | |
| data-parent_id="ev-0-0-2-0"> | |
| <a href="#" | |
| > | |
| ➶ | |
| </a> | |
| </div> | |
| <div class="col-9 nvp src-api" | |
| title="reach"> | |
| reach | |
| </div> | |
| </div> | |
| </div> | |
| <div class="col-9"> | |
| "A comparison between the cytokine concentrations secreted by splenocytes from Combo5 / alum and Combo5 / <span class="badge badge-subject">SMQ</span> immune mice showed that the <span class="badge badge-subject">SMQ</span> adjuvanted formulation induced significantly higher secretion of <span class="badge badge-object">IL-6</span>, IL-10, IFN-γ, and TNF-α than the alum adjuvanted formulation." | |
| </div> | |
| <div class="col-2 text-right"> | |
| <a class="pmid_link" | |
| title="Hover again to see info" | |
| onmouseover="setPMIDlinkTitle(this.textContent, this); this.onmouseover=null;" | |
| href='https://www.ncbi.nlm.nih.gov/pubmed/32156809' | |
| target="_blank"> | |
| 32156809</a> | |
| <a class="full_text_search" | |
| data-sentence= 'A%20comparison%20between%20the%20cytokine%20concentrations%20secreted%20by%20splenocytes%20from%20Combo5%20/%20alum%20and%20Combo5%20/%20%3Cspan%20class%3D%22badge%20badge-subject%22%3ESMQ%3C/span%3E%20immune%20mice%20showed%20that%20the%20%3Cspan%20class%3D%22badge%20badge-subject%22%3ESMQ%3C/span%3E%20adjuvanted%20formulation%20induced%20significantly%20higher%20secretion%20of%20%3Cspan%20class%3D%22badge%20badge-object%22%3EIL-6%3C/span%3E%2C%20IL-10%2C%20IFN-%CE%B3%2C%20and%20TNF-%CE%B1%20than%20the%20alum%20adjuvanted%20formulation.' | |
| href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7064752" target=_blank rel=noopener >Full-Text Search: PMC7064752</a> | |
| <span style="cursor:default" title="This link will search for and highlight the sentence in the full-text article. Works with Chrome 80+"> ⓘ</span> | |
| </div> | |
| </div> | |
| </div> <!-- container --> | |
| </div> <!-- row evidence --> | |
| <a name="30554384213470801"></a> | |
| <div class="row statement"> | |
| <div class="col text-left nvp"> | |
| <h5 class="align-middle"> | |
| SMQ activates <a href='https://identifiers.org/hgnc/HGNC:5962' target='_blank'>IL10</a>. | |
| <a href="#" | |
| > | |
| <small class="badge badge-secondary badge-pill">1</small> | |
| </a> | |
| </h5> | |
| </div> | |
| <div class="col text-right nvp"> | |
| </div> | |
| </div> | |
| <div class="row evidence"> | |
| <div class="container" id="stmt-0-0-3" | |
| data-stmt_hash="30554384213470801"> | |
| <div class="row evidence-text" data-source_hash="4155885927386739680" | |
| style="border-bottom: 1px solid #FFFFFF;" | |
| id="ev-0-0-3-0"> | |
| <div class="col-1"> | |
| <div class="row"> | |
| <div class="col-3 nvp curation_toggle" | |
| id="ev-0-0-3-0-click" | |
| data-parent_id="ev-0-0-3-0"> | |
| <a href="#" | |
| > | |
| ➶ | |
| </a> | |
| </div> | |
| <div class="col-9 nvp src-api" | |
| title="reach"> | |
| reach | |
| </div> | |
| </div> | |
| </div> | |
| <div class="col-9"> | |
| "A comparison between the cytokine concentrations secreted by splenocytes from Combo5 / alum and Combo5 / <span class="badge badge-subject">SMQ</span> immune mice showed that the <span class="badge badge-subject">SMQ</span> adjuvanted formulation induced significantly higher secretion of IL-6, <span class="badge badge-object">IL-10</span>, IFN-γ, and TNF-α than the alum adjuvanted formulation." | |
| </div> | |
| <div class="col-2 text-right"> | |
| <a class="pmid_link" | |
| title="Hover again to see info" | |
| onmouseover="setPMIDlinkTitle(this.textContent, this); this.onmouseover=null;" | |
| href='https://www.ncbi.nlm.nih.gov/pubmed/32156809' | |
| target="_blank"> | |
| 32156809</a> | |
| <a class="full_text_search" | |
| data-sentence= 'A%20comparison%20between%20the%20cytokine%20concentrations%20secreted%20by%20splenocytes%20from%20Combo5%20/%20alum%20and%20Combo5%20/%20%3Cspan%20class%3D%22badge%20badge-subject%22%3ESMQ%3C/span%3E%20immune%20mice%20showed%20that%20the%20%3Cspan%20class%3D%22badge%20badge-subject%22%3ESMQ%3C/span%3E%20adjuvanted%20formulation%20induced%20significantly%20higher%20secretion%20of%20IL-6%2C%20%3Cspan%20class%3D%22badge%20badge-object%22%3EIL-10%3C/span%3E%2C%20IFN-%CE%B3%2C%20and%20TNF-%CE%B1%20than%20the%20alum%20adjuvanted%20formulation.' | |
| href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7064752" target=_blank rel=noopener >Full-Text Search: PMC7064752</a> | |
| <span style="cursor:default" title="This link will search for and highlight the sentence in the full-text article. Works with Chrome 80+"> ⓘ</span> | |
| </div> | |
| </div> | |
| </div> <!-- container --> | |
| </div> <!-- row evidence --> | |
| <a name="13465087121692280"></a> | |
| <div class="row statement"> | |
| <div class="col text-left nvp"> | |
| <h5 class="align-middle"> | |
| SMQ activates IFN-γ. | |
| <a href="#" | |
| > | |
| <small class="badge badge-secondary badge-pill">1</small> | |
| </a> | |
| </h5> | |
| </div> | |
| <div class="col text-right nvp"> | |
| </div> | |
| </div> | |
| <div class="row evidence"> | |
| <div class="container" id="stmt-0-0-4" | |
| data-stmt_hash="13465087121692280"> | |
| <div class="row evidence-text" data-source_hash="4155885927386739680" | |
| style="border-bottom: 1px solid #FFFFFF;" | |
| id="ev-0-0-4-0"> | |
| <div class="col-1"> | |
| <div class="row"> | |
| <div class="col-3 nvp curation_toggle" | |
| id="ev-0-0-4-0-click" | |
| data-parent_id="ev-0-0-4-0"> | |
| <a href="#" | |
| > | |
| ➶ | |
| </a> | |
| </div> | |
| <div class="col-9 nvp src-api" | |
| title="reach"> | |
| reach | |
| </div> | |
| </div> | |
| </div> | |
| <div class="col-9"> | |
| "A comparison between the cytokine concentrations secreted by splenocytes from Combo5 / alum and Combo5 / <span class="badge badge-subject">SMQ</span> immune mice showed that the <span class="badge badge-subject">SMQ</span> adjuvanted formulation induced significantly higher secretion of IL-6, IL-10, <span class="badge badge-object">IFN-γ</span>, and TNF-α than the alum adjuvanted formulation." | |
| </div> | |
| <div class="col-2 text-right"> | |
| <a class="pmid_link" | |
| title="Hover again to see info" | |
| onmouseover="setPMIDlinkTitle(this.textContent, this); this.onmouseover=null;" | |
| href='https://www.ncbi.nlm.nih.gov/pubmed/32156809' | |
| target="_blank"> | |
| 32156809</a> | |
| <a class="full_text_search" | |
| data-sentence= 'A%20comparison%20between%20the%20cytokine%20concentrations%20secreted%20by%20splenocytes%20from%20Combo5%20/%20alum%20and%20Combo5%20/%20%3Cspan%20class%3D%22badge%20badge-subject%22%3ESMQ%3C/span%3E%20immune%20mice%20showed%20that%20the%20%3Cspan%20class%3D%22badge%20badge-subject%22%3ESMQ%3C/span%3E%20adjuvanted%20formulation%20induced%20significantly%20higher%20secretion%20of%20IL-6%2C%20IL-10%2C%20%3Cspan%20class%3D%22badge%20badge-object%22%3EIFN-%CE%B3%3C/span%3E%2C%20and%20TNF-%CE%B1%20than%20the%20alum%20adjuvanted%20formulation.' | |
| href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7064752" target=_blank rel=noopener >Full-Text Search: PMC7064752</a> | |
| <span style="cursor:default" title="This link will search for and highlight the sentence in the full-text article. Works with Chrome 80+"> ⓘ</span> | |
| </div> | |
| </div> | |
| </div> <!-- container --> | |
| </div> <!-- row evidence --> | |
| <a name="-31029788656818151"></a> | |
| <div class="row statement"> | |
| <div class="col text-left nvp"> | |
| <h5 class="align-middle"> | |
| <a href='https://identifiers.org/chebi/CHEBI:51079' target='_blank'>GS26575</a> activates <a href='https://identifiers.org/hgnc/HGNC:4164' target='_blank'>GAST</a>. | |
| <a href="#" | |
| > | |
| <small class="badge badge-secondary badge-pill">1</small> | |
| </a> | |
| </h5> | |
| </div> | |
| <div class="col text-right nvp"> | |
| </div> | |
| </div> | |
| <div class="row evidence"> | |
| <div class="container" id="stmt-0-0-5" | |
| data-stmt_hash="-31029788656818151"> | |
| <div class="row evidence-text" data-source_hash="-5164385967986893407" | |
| style="border-bottom: 1px solid #FFFFFF;" | |
| id="ev-0-0-5-0"> | |
| <div class="col-1"> | |
| <div class="row"> | |
| <div class="col-3 nvp curation_toggle" | |
| id="ev-0-0-5-0-click" | |
| data-parent_id="ev-0-0-5-0"> | |
| <a href="#" | |
| > | |
| ➶ | |
| </a> | |
| </div> | |
| <div class="col-9 nvp src-api" | |
| title="reach"> | |
| reach | |
| </div> | |
| </div> | |
| </div> | |
| <div class="col-9"> | |
| "Only <span class="badge badge-subject">M1</span> immune sera was able to promote opsonophagocytic killing of <span class="badge badge-object">GAS</span> (XREF_FIG) with an opsonic index significantly higher than that measured for naive mice." | |
| </div> | |
| <div class="col-2 text-right"> | |
| <a class="pmid_link" | |
| title="Hover again to see info" | |
| onmouseover="setPMIDlinkTitle(this.textContent, this); this.onmouseover=null;" | |
| href='https://www.ncbi.nlm.nih.gov/pubmed/32156809' | |
| target="_blank"> | |
| 32156809</a> | |
| <a class="full_text_search" | |
| data-sentence= 'Only%20%3Cspan%20class%3D%22badge%20badge-subject%22%3EM1%3C/span%3E%20immune%20sera%20was%20able%20to%20promote%20opsonophagocytic%20killing%20of%20%3Cspan%20class%3D%22badge%20badge-object%22%3EGAS%3C/span%3E%20%28XREF_FIG%29%20with%20an%20opsonic%20index%20significantly%20higher%20than%20that%20measured%20for%20naive%20mice.' | |
| href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7064752" target=_blank rel=noopener >Full-Text Search: PMC7064752</a> | |
| <span style="cursor:default" title="This link will search for and highlight the sentence in the full-text article. Works with Chrome 80+"> ⓘ</span> | |
| </div> | |
| </div> | |
| </div> <!-- container --> | |
| </div> <!-- row evidence --> | |
| <a name="-12695682573761343"></a> | |
| <div class="row statement"> | |
| <div class="col text-left nvp"> | |
| <h5 class="align-middle"> | |
| Combo5 activates <a href='https://identifiers.org/go/GO:0006955' target='_blank'>immune response</a>. | |
| <a href="#" | |
| > | |
| <small class="badge badge-secondary badge-pill">1</small> | |
| </a> | |
| </h5> | |
| </div> | |
| <div class="col text-right nvp"> | |
| </div> | |
| </div> | |
| <div class="row evidence"> | |
| <div class="container" id="stmt-0-0-6" | |
| data-stmt_hash="-12695682573761343"> | |
| <div class="row evidence-text" data-source_hash="597975201937205239" | |
| style="border-bottom: 1px solid #FFFFFF;" | |
| id="ev-0-0-6-0"> | |
| <div class="col-1"> | |
| <div class="row"> | |
| <div class="col-3 nvp curation_toggle" | |
| id="ev-0-0-6-0-click" | |
| data-parent_id="ev-0-0-6-0"> | |
| <a href="#" | |
| > | |
| ➶ | |
| </a> | |
| </div> | |
| <div class="col-9 nvp src-api" | |
| title="reach"> | |
| reach | |
| </div> | |
| </div> | |
| </div> | |
| <div class="col-9"> | |
| "We further characterized the protective <span class="badge badge-object">immune response</span> elicited by <span class="badge badge-subject">Combo5</span> formulated with SMQ adjuvant and compared this to the nonprotective response elicited by <span class="badge badge-subject">Combo5</span> / alum and to the protective response elicited by the “ gold standard ” homologous M1 protein formulated with alum." | |
| </div> | |
| <div class="col-2 text-right"> | |
| <a class="pmid_link" | |
| title="Hover again to see info" | |
| onmouseover="setPMIDlinkTitle(this.textContent, this); this.onmouseover=null;" | |
| href='https://www.ncbi.nlm.nih.gov/pubmed/32156809' | |
| target="_blank"> | |
| 32156809</a> | |
| <a class="full_text_search" | |
| data-sentence= 'We%20further%20characterized%20the%20protective%20%3Cspan%20class%3D%22badge%20badge-object%22%3Eimmune%20response%3C/span%3E%20elicited%20by%20%3Cspan%20class%3D%22badge%20badge-subject%22%3ECombo5%3C/span%3E%20formulated%20with%20SMQ%20adjuvant%20and%20compared%20this%20to%20the%20nonprotective%20response%20elicited%20by%20%3Cspan%20class%3D%22badge%20badge-subject%22%3ECombo5%3C/span%3E%20/%20alum%20and%20to%20the%20protective%20response%20elicited%20by%20the%20%E2%80%9C%20gold%20standard%20%E2%80%9D%20homologous%20M1%20protein%20formulated%20with%20alum.' | |
| href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7064752" target=_blank rel=noopener >Full-Text Search: PMC7064752</a> | |
| <span style="cursor:default" title="This link will search for and highlight the sentence in the full-text article. Works with Chrome 80+"> ⓘ</span> | |
| </div> | |
| </div> | |
| </div> <!-- container --> | |
| </div> <!-- row evidence --> | |
| </div> <!-- PA Statement container --> | |
| </div> <!-- PA Statement group --> | |
| </div> <!-- container --> | |
| </div> <!-- type groups --> | |
| <hr> | |
| <!-- Footer --> | |
| <footer class="footer text-muted" id="about"> | |
| <h5 class="my-0 mr-md-auto font-weight-normal">About</h5> | |
| INDRA is developed by <a href="https://indralab.github.io/">indralabs</a>, | |
| a part of the Harvard Medical School Laboratory of Systems Pharmacology. | |
| </footer> | |
| </div> | |
| </body> | |
| </html> |
This file contains bidirectional Unicode text that may be interpreted or compiled differently than what appears below. To review, open the file in an editor that reveals hidden Unicode characters.
Learn more about bidirectional Unicode characters
| import json | |
| from indra.sources import reach, trips | |
| from indra.statements.statements import stmts_to_json | |
| from indra.assemblers.html.assembler import HtmlAssembler | |
| from indra.assemblers.english.assembler import EnglishAssembler | |
| from indra.assemblers.tsv.assembler import TsvAssembler | |
| ha = HtmlAssembler() | |
| reach_processor_1 = reach.api.process_pmc("7064752") | |
| stmts = reach_processor_1.statements | |
| ha.add_statements(stmts) | |
| html = ha.make_model(template=None, with_grouping=False, add_full_text_search_link=True) | |
| ha.save_model('output.html') |
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