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PMID JOURNAL_TITLE YEAR PMCID MESH_TERMS | |
10021361 Curr. Biol. 1999 Humans|SLP-76 signal Transducing adaptor proteins|*Phosphoproteins|*Signal Transduction|GRB2 protein, human|GRB2 Adaptor Protein|SH3 Domains|Receptors, Antigen, T-Cell|Carrier Proteins|Phosphorylation|Nuclear Proteins|DNA-Binding Proteins|Membrane Proteins|Jurkat Cells|NFATC Transcription Factors|Binding Sites|*Hematopoietic System|Amino Acid Sequence|Tyrosine | |
10022829 EMBO J. 1999 PMC1171179 Mice|Animals|laminin A|*Laminin|perlecan|*Dystroglycans|*Heparin|*Sulfoglycosphingolipids|*Heparan Sulfate Proteoglycans|fibulin 2|*Extracellular Matrix Proteins|nidogen|Membrane Glycoproteins|gephyrin|Calcium-Binding Proteins|Heparitin Sulfate|Protein Binding|Binding Sites|Recombinant Proteins|Basement Membrane | |
10022833 EMBO J. 1999 PMC1171183 *Stem Cell Factor|GRB2 protein, human|GRB2 Adaptor Protein|SH3 Domains|Signal Transduction|*Suppressor of Cytokine Signaling Proteins|Phosphorylation|Receptor Protein-Tyrosine Kinases|Proto-Oncogene Proteins c-kit|Proto-Oncogene Proteins c-vav|Protein Binding|Tyrosine|Cell Proliferation | |
10022860 Mol. Cell. Biol. 1999 PMC83966 Rats|Mice|Animals|*ral Guanine Nucleotide Exchange Factor|*PC12 Cells|ras Proteins|Signal Transduction|PI3-Kinase|Guanine Nucleotide Exchange Factors|ral GTP-Binding Proteins|RTN4 protein, human|*Nogo Proteins|NGF protein, human|Nerve Growth Factor|rho GTPases|ras Guanine Nucleotide Exchange Factors|Proto-Oncogene Proteins c-raf|Cell Differentiation|Neurite Outgrowth | |
10022869 Mol. Cell. Biol. 1999 PMC83975 *Transforming Growth Factor beta|*Transcriptional Activation|*Transcription Factor AP-1|SMAD3 protein, human|*Smad3 Protein|SMAD4 protein, human|*Smad4 Protein|*Promoter Regions, Genetic|Trans-Activators|Proto-Oncogene Proteins c-jun|Gene Expression Regulation|Transcription, Genetic|Binding Site|*Cell Nucleus|Genes, Reporter|Protein Binding|Transfection|Luciferases | |
10022900 Mol. Cell. Biol. 1999 PMC84006 Humans|*RNA Polymerase II|U1 small nuclear RNA|*Small Nuclear RNA|*Transcription Factor TFIIA|TATA Box|*Promoter Regions, Genetic|TATA-Binding Protein|Transcription, Genetic|RNA Polymerase III|Transcription Factors|DNA-Binding Proteins|Cell Nucleus|Base Sequence|Cloning, Molecular | |
10022904 Mol. Cell. Biol. 1999 PMC84010 CHUK protein, human|*I-kappa B Kinase|PKC-3 protein|*Protein Kinase C|protein kinase C zeta|Signal Transduction|I-kappa B Proteins|NF-kappa B|Phosphorylation|Enzyme Activation|Tumor Necrosis Factor-alpha|*Isoforms|Transfection|Phorbol Myristate Acetate|Cell Line | |
10022913 Mol. Cell. Biol. 1999 PMC84019 Animals|Humans|*Saccharomyces cerevisiae|PTS2 Protein|Peroxins|Peroxisomes|Saccharomyces cerevisiae Proteins|Peroxisome-Targeting Signal 1 Receptor|Membrane Protein|Receptors, Cytoplasmic and Nuclear|Carrier Proteins|Membrane Transport Proteins|*Yeast, Dried|Microbodies|Intracellular Membranes|Protein Transport|Amino Acid Sequence|Repressor Proteins|Protein Binding|Cloning, Molecular | |
10022914 Mol. Cell. Biol. 1999 PMC84020 Animals|Humans|*Focal Adhesion Kinase 2|*Retinal Degeneration|rdgB protein, Drosophila|*Eye Proteins|*Drosophila Proteins|Drosophila|Phosphatidylinositol Transfer Protein|Cloning, Molecular|Calcium-Binding Proteins|Amino Acid Sequence|Retina|Phosphorylation|Gene Expression | |
10022928 Mol. Cell. Biol. 1999 PMC84034 Animals|Mice|PTPN11 protein, human|*Protein Tyrosine Phosphatase, Non-Receptor Type 11|STAT1 protein, human|STAT1 Transcription Factor|SH2 Domain-Containing Protein Tyrosine Phosphatase|*Antiviral Agents|Janus Kinase 1|STAT2 Transcription Factor|Phosphorylation|Interferon-alpha|Protein Tyrosine Phosphatase, Non-Receptor Type 6|Signal Transduction|Trans-Activators|Interferon-gamma|STAT3 Transcription Factor | |
10023660 Oncogene 1999 Animals|Humans|*beta-Transducin Repeat-Containing Proteins|CTNNB1 protein, human|*beta Catenin|Cullin 1|*Cullin Proteins|*F-Box Proteins|F protein, human|Ubiquitins|Cell Cycle Proteins|UBB protein, human|Ubiquitin|SKP Cullin F-Box Protein Ligases|Trans-Activators|DNA-Binding Proteins|I-kappa B Proteins|Transcription Factors|Ligases|Wnt beta-Catenin Signaling Pathway | |
10023775 Immunity 1999 Humans|*Multiple Myeloma|Cell Line, Tumor|BCL2L1 protein, human|bcl-XL Protein|*Apoptosis|STAT3 protein, human|STAT3 Protein|*Signal Transduction|Proto-Oncogene Proteins c-bcl-2|Tyrphostins|Janus Kinase 2|Janus Kinase 1|Interleukin 6|DNA-Binding Proteins|Trans-Activators|Phosphorylation | |
10023777 Immunity 1999 Humans|Mice|Animals|interleukin-18 binding protein|*Intercellular Signaling Peptides and Proteins|interleukin 18 protein, human|IL-18|*Cytokines|Interferon-gamma|Interleukin-12|Cloning, Molecular|Amino Acid Sequence|Lipopolysaccharides|Spleen|Gene Expression|Exon | |
10024882 Mol. Cell 1999 *Transcription Factor TFIIH|DNA Helicases|Transcription Factors|Xeroderma Pigmentosum Group D Protein|RNA Pol II|DNA Repair|Transcription, Genetic|Cyclin-Dependent Kinases|Promoter Regions, Genetic|Protein-Serine-Threonine Kinases|Mutation|Baculovirus | |
10025398 Cell 1999 Mice|Animals|TGFB1 protein, human|*Transforming Growth Factor beta1|*Integrin alphaV|integrin alphavbeta6|*Integrins|*Antigens, Neoplasm|Transforming Growth Factor beta|Pulmonary Fibrosis|*Pulmonary Inflammation|Ligands|Protein Precursors|Peptides|Peptide Fragments|*Fibrosis | |
10026136 J. Biol. Chem. 1999 Cricetinae|Animals|IGFBP3 protein, human|*Insulin-Like Growth Factor Binding Protein 3|*Glycosylation|Cricetulus|IGF1 protein, human|Insulin-Like Growth Factor I|glycosylated serum protein|Glycoproteins|Carrier Proteins|CHO Cells|Protein Binding | |
10026152 J. Biol. Chem. 1999 PMC2388248 *Receptors, Erythropoietin|STAT5A protein, human|STAT5 Transcription Factor|Signal Transduction|JAK2 protein, human|Janus Kinase 2|Erythropoietin|Cell Membrane|Phosphorylation|Cytoplasm|Amino Acid Sequence|Cell Division|Cell Proliferation|Cell Line|Tumor Suppressor Proteins | |
10026158 J. Biol. Chem. 1999 *Protein S|drotrecogin alfa activated|*Protein C|*Fluorescence Resonance Energy Transfer|*Catalytic Domain|Factor Va|Prothrombin|Protein Binding|Amino Acid Sequence|PROS1 protein, human|Phospholipids|Kinetics|Arginine | |
10026192 J. Biol. Chem. 1999 Humans|Animals|*eIF-2 Kinase|*Somatostatin|*Somatostatin-Secreting Cells|Eukaryotic Initiation Factor-2|Protein Biosynthesis|*Pancreatic Islets|Phosphorylation|Protein-Serine-Threonine Kinases|Amino Acid Sequence|Saccharomyces cerevisiae|mRNA|*Pancreas|Sequence Homology, Amino Acid|Cloning, Molecular | |
10026212 J. Biol. Chem. 1999 Animals|Humans|Cattle|*Farnesyltranstransferase|*DNA, Complementary|geranylgeranyl pyrophosphate|Polyisoprenyl Phosphates|Prenylation, Protein|farnesyl pyrophosphate|Cloning, Molecular|Geranyltranstransferase|Transferases|Amino Acid Sequence|Sequence Homology, Amino Acid|Escherichia coli|mRNA|Kinetics | |
10026222 J. Biol. Chem. 1999 *Receptor, Collagen|*Blood Platelets|*Phosphorylation|SLP-76 signal Transducing adaptor proteins|*Phosphoproteins|*Adaptor Proteins, Signal Transducing|collagen-related peptide|Carrier Proteins|Platelet Activation|Phospholipase C gamma2|Tyrosine Kinase|Intracellular Signaling Peptides and Proteins|Syk Kinase|Fc gamma receptor IIA|Receptors, IgG|src-Family Kinases|Membrane Proteins|Peptides | |
10026247 Biochemistry 1999 Humans|S100A7 protein, human|*S100 Calcium Binding Protein A7|*Calcium|*Zinc|*S100 Proteins|*Binding Site|EF Hand|Amino Acid Sequence|Protein Binding|Crystallography, X-Ray|Models, Molecular|Dimerization|Sequence Alignment|Histidine|*Protein Domains | |
10028968 Nature 1999 Animals|*Drosophila|Receptor, Frizzled|Drosophila Proteins|Photoreceptor Cells, Invertebrate|Receptors, Notch|Signal Transduction|Cell Polarity|Receptors, G-Protein-Coupled|Membrane Proteins|Cell Lineage|Cell Differentiation|Eye|Animals, Genetically Modified|notch protein, Drosophila|dsh protein, Drosophila|Dishevelled Proteins | |
10029069 Cancer Res. 1999 Male|Humans|MSH4 protein, human|*Cell Cycle Proteins|G-T mismatch-binding protein|DNA-Binding Proteins|Saccharomyces cerevisiae|Meiosis|Saccharomyces cerevisiae Proteins|*Spermatogenesis|MSH3 protein, human|MutS Homolog 3 Protein|Amino Acid Sequence|Cloning, Molecular|*Dimerization|Chromosome Mapping|Spermatocytes|MSH5 protein, S cerevisiae | |
10029519 Biochemistry 1999 Humans|*GTP-Binding Protein alpha Subunits, Gs|HEK293 Cells|*G Proteins|GTPgammaS|Pertussis Toxin|*Receptor, Adenosine A1|G(o) Protein|Virulence Factors, Bordetella|N-Ethylcarboxamidoadenosine|Cysteine|Transfection | |
10036181 Genomics 1999 Humans|Animals|Rats|In Situ Hybridization, Fluorescence|GPRC5C protein, human|*G-Protein-Coupled Receptors|Receptors, Cell Surface|GTP-Binding Proteins|Amino Acid Sequence|Cloning, Molecular|Base Sequence|Gene Library|cDNA|Chromosome Mapping|Polymerase Chain Reaction|Nerve Tissue Proteins|Sequence Homology, Amino Acid|mRNA|Expressed Sequence Tags|DNA Primers|Northern Blot | |
10036229 J. Cell. Sci. 1999 *Dyneins|*Kinesin|Microtubules|Biological Transport|Lysosomes|*Genes, MHC Class II|*Ion Transport|Microtubule-Organizing Center|*Biochemical Phenomena|Cell Movement|MHC Class II Molecules|Motor Activity | |
10036316 Biochim. Biophys. Acta 1999 *Mucopolysaccharidosis VI|N-Acetylgalactosamine-4-Sulfatase|DNA Mutational Analysis|Mutation|Exons|Point Mutations|Protein Conformation | |
10037601 Science 1999 Animals|*Telomere|*Tumor Suppressor Protein p53|TERF2 protein, human|Telomeric Repeat Binding Protein 2|Cell Cycle Proteins|DNA Damage|Ataxia Telangiectasia Mutated Proteins|Tumor Suppressor Proteins|Ataxia-Telangiectasia|DNA-Binding Proteins|*Apoptosis|Cell Cycle Checkpoints | |
10037737 J. Biol. Chem. 1999 Humans|*Vascular Endothelial Growth Factor B|*Vascular Endothelial Growth Factor A|*Vascular Endothelial Growth Factor Receptor-2|*Tyrosine|FLT1 protein, human|Vascular Endothelial Growth Factor Receptor-1|*Phosphorylation|Tyrosine Kinase Receptors|Receptors, Vascular Endothelial Growth Factor|Receptors, Growth Factor|Vascular Endothelial Growth Factors|Signal Transduction|Proto-Oncogene Proteins|Protein Binding|Binding Site|Recombinant Proteins | |
10037746 J. Biol. Chem. 1999 Humans|Animals|Guanylyl Cyclase Activating Proteins|Ca2+-binding protein-1|Calcium-Binding Proteins|Photoreceptor Cells|Guanylyl Cyclase|Retina|Amino Acid Sequence|Cloning, Molecular|Mammals|Chromosome | |
10037775 J. Biol. Chem. 1999 Humans|Cricetinae|Animals|Mice|*Ornithine|*Ornithine-Oxo-Acid Transaminase|CHO Cells|Cricetulus|1-Pyrroline-5-Carboxylate Dehydrogenase|glutamate 5-kinase|Phosphotransferases (Carboxyl Group Acceptor)|cDNA|Proline|Amino Acid Sequence|Base Sequence|Oxidoreductases Acting on CH-NH Group Donors|Cloning, Molecular|*Isoforms|Glutamate|Plant|*Mammals|*Nitric Oxide Synthase | |
10037799 J. Cell Biol. 1999 PMC2132933 *Hyaluronic Acid|CD44 protein, human|*Receptor, Hyaluronan|*Glycoprotein|Amino Acid Sequence|Lymphatic Vessels|Vesicular Transport Proteins|Glycosaminoglycans|Cell Migration|Protein Binding|Lymph Nodes | |
10047984 J. Muscle Res. Cell. Motil. 1999 *Myosin Regulatory Light Chain|*p21-Activated Kinases|*Phosphorylation|Myosin Light Chain Kinase|ROCK1 protein, human|rho-Kinase|Myosin II|Actin|cdc42 GTP-Binding Protein|Calmodulin | |
10049700 Biochem. Biophys. Res. Commun. 1999 Pregnancy|Humans|Rats|Female|Animals|*Amino Acid Transport System L|*Cloning, Molecular|Amino Acid Transport Systems|Amino Acids|Carrier Proteins|Biological Transport|Amino Acid Sequence|4F2 Antigen|cDNA|Xenopus laevis|mRNA|Substrate Specificity|Sequence Homology, Amino Acid|Oocytes | |
10049739 Biochem. Biophys. Res. Commun. 1999 Humans|Rats|Mice|Animals|*Organic Anion Transporters|p Aminohippurate|Organic Anion Transport Protein 1|Organic Anion Transporters, Sodium-Independent|*Kidney|Biological Transport|*Cloning, Molecular|Xenopus laevis|Oocytes|cDNA|Furosemide|Bumethanide|mRNA | |
10049780 Biochem. Biophys. Res. Commun. 1999 Humans|*Endostatins|cytoplasmic linker protein 170|Endothelial Cells|Tomography, X-Ray Computed|Collagen XVIII|*Microtubule-Associated Proteins|*Neoplasm Proteins|COL15A1 protein, human|*Collagen|*Angiogenesis Inhibitors|Carcinoma, Renal Cell|Cell Division|Kidney Neoplasms|*Cytoskeletal Proteins|Peptide Fragments|Amino Acid Sequence|Cloning, Molecular|Endothelium, Vascular | |
10049942 J. Exp. Med. 1999 PMC2192947 Humans|NCR2 protein, human|*Natural Cytotoxicity Triggering Receptor 2|*Natural Killer Cell|Natural Cytotoxicity Triggering Receptor 1|Cytotoxicity, Immunologic|*Immunoglobulin|Receptors, Immunologic|*Carrier Proteins|Amino Acid Sequence|Signal Transduction|Cloning, Molecular|cDNA | |
10050855 Nature 1999 Animals|*Hedgehog Proteins|Patched Protein|PTCH protein, human|Patched-1 Receptor|*Signal Transduction|HHIP protein, human|*Binding Protein|Body Patterning|Membrane Glycoprotein|Receptors, Cell Surface|Trans-Activators|Membrane Protein|*Vertebrate|Gene Expression Regulation, Developmental|Intracellular Signaling Peptides and Proteins|Embryogenesis | |
10051404 Genomics 1999 Mice|Humans|Animals|*Steroid 12-alpha-Hydroxylase|*Introns|*Eukaryotes|*Cytochrome P450|Promoter Regions, Genetic|Steroid Hydroxylases|Transcription, Genetic|Base Sequence|DNA-Binding Proteins|DNA|Complementary DNA|Chromosome Mapping|Regulatory Sequences, Nucleic Acid|mRNA|Hepatocyte Nuclear Factor 4|Transfection|Amino Acid Sequence|Gene Expression Regulation | |
10051567 Proc. Natl. Acad. Sci. U.S.A. 1999 PMC26709 Humans|Mice|Animals|Vascular Endothelial Growth Factor A|angiopoietin 4|*Angiopoietins|ANGPT1 protein, human|Angiopoietin-1|ANGPT2 protein, human|Angiopoietin 2|Tie2 Receptor|Receptors, TIE|Growth Factors|Amino Acid Sequence|Receptor Protein-Tyrosine Kinases|Neoplasm Proteins|Angiopoietin-like Proteins|Sequence Homology, Amino Acid|Membrane Glycoproteins|RNA, Messenger | |
10051570 Proc. Natl. Acad. Sci. U.S.A. 1999 PMC26712 Animals|*DNA, Single-Stranded|*DNA Damage|*Cell Nucleus|RAD51 Protein|Replication Protein A|DNA Repair|DNA-Binding Proteins|Nuclear Proteins|Cell Line|Gamma Rays|Recombination, Genetic | |
10051575 Proc. Natl. Acad. Sci. U.S.A. 1999 PMC26717 *Transducin|*GTPase Activators|*GTP-Binding Protein beta Subunits|*Rod Photoreceptors|RGS Proteins|Rod Cell Outer Segment|Photoreceptors, Vertebrate|Signal Transduction|G Protein|GTP Phosphohydrolases|Vision, Ocular|3',5'-Cyclic-GMP Phosphodiesterases|Kinetics | |
10051622 Proc. Natl. Acad. Sci. U.S.A. 1999 PMC26764 *Phosphorylation|BTK protein, human|*Agammaglobulinaemia Tyrosine Kinase|*Phosphopeptide-Specific Antibodies|*Phosphopeptides|Receptors, Antigen, B-Cell|*Signal Transduction|src-Family Kinases|Protein-Tyrosine Kinases|SH3 Domain|B Cells|Phosphotyrosine|Enzyme Activation|Tyrosine|Kinetics|Amino Acid Sequence|Cell Line|Antibodies, Monoclonal | |
10052452 Cell 1999 Animals|Golgi Apparatus|*Carrier Proteins|Membrane Proteins|COPI-Coated Vesicles|Coatomer Protein|Intracellular Membranes|ADP-Ribosylation Factors|Endoplasmic Reticulum|Guanosine 5'-O-(3-Thiotriphosphate)|Biological Transport|Guanosine Triphosphate|GTP-Binding Proteins|Lipid Bilayers|Microtubule-Associated Proteins | |
10052453 Cell 1999 Mice|Animals|*Vitamin|Heymann Nephritis Antigenic Complex|*Calcifediol|LRP2 protein, human|Megalin|*Kidney|Kidney Tubules, Proximal|GC, vitamin D binding protein, human|Vitamin D-Binding Protein|*Biological Transport|Endocytosis|Plasma Membrane|Kidney Glomerulus|Membrane Glycoproteins|*Steroids|Hormones | |
10052934 Biochemistry 1999 Humans|*Prealbumin|*Carrier Proteins|Vitamin A|Retinol-Binding Proteins, Plasma|Protein Binding|Biological Transport|Amino Acids | |
10052942 Biochemistry 1999 Animals|Humans|*Cystathionine beta-Synthase|*Hemeproteins|*Pyridoxal Phosphate|Haem|Cystathionine|Binding Sites|Protein Structure, Secondary|Amino Acid Sequence|Serine|Models, Molecular|Catalysis|dehydroalanine|Alanine|Phosphates | |
10053006 Am. J. Hum. Genet. 1999 PMC1377789 Humans|Child, Preschool|Child|*Acanthosis Nigricans|Thanatophoric Dysplasia, Type I|FGFR3 protein, human|*Receptor, Fibroblast Growth Factor, Type 3|Thanatophoric Dysplasia|Achondroplasia, Severe, With Developmental Delay And Acanthosis Nigricans|*Osteochondrodysplasias|*Mutation|Amino Acid Substitution|Missense Mutation|Phenotype|Point Mutation|Codon|*Musculoskeletal Abnormalities | |
10064069 Eur. J. Immunol. 1999 Humans|Mice|Animals|*Alleles|Histocompatibility Antigens Class I|beta 2-Microglobulin|Genes, MHC Class I|*B-Lymphocytes|Transfection|Peptides|Flow Cytometry|Cell Membrane|Histocompatibility Antigens Class II | |
10064083 Eur. J. Immunol. 1999 Animals|Cattle|invariant chain|Antigens, Differentiation, B-Lymphocyte|HLA-D Antigens|HLA-DR1|Antigen Presentation|Amino Acid Sequence|*Cell Surface Display Techniques|Peptides|T Cells|Kinetics|Bacteriophage | |
10064314 J. Nutr. 1999 Humans|*Biotinidase|*Biotin|Biotinylation|Amidohydrolases|Histones|Coenzymes|Cell Nucleus | |
10064597 EMBO J. 1999 PMC1171221 *Phosphorylation|*Tyrosine|*Suppressor of Cytokine Signaling Proteins|JAK2 protein, human|Janus Kinase 2|SH2 Domain|Signal Transduction|Intracellular Signaling Peptides and Proteins|Suppressor of Cytokine Signaling 1 Protein|Repressor Proteins|DNA-Binding Proteins|Trans-Activators|Immediate-Early Proteins|Amino Acid Sequence | |
10064732 J. Lipid Res. 1999 Humans|*Leukotriene C4|multidrug resistance-associated protein 1|*Blood Platelets|*Multidrug Resistance-Associated Proteins|Leukotriene A4|leukotriene-C4 synthase|Glutathione Transferase|SRS-A|MK-886|Indoles|Glutathione | |
10066432 Biochem. Biophys. Res. Commun. 1999 Humans|*Cysteine|CD163 antigen|*Antigens, Differentiation, Myelomonocytic|*Antigens, CD|*Receptors, Cell Surface|*Scavenger Receptor|Monocytes|Macrophages|Phorbol Myristate Acetate|Membrane Proteins|Glucocorticoid|Protein Kinase C|bisindolylmaleimide I|Maleimides|Indoles | |
10066435 Biochem. Biophys. Res. Commun. 1999 NFKBIA protein, human|*NF-KappaB Inhibitor alpha|Cullin 1|*Cullin Proteins|*F-Box Proteins|I-kappa B Proteins|*Ubiquitination|Ubiquitins|DNA-Binding Proteins|beta-Transducin Repeat-Containing Proteins|Ubiquitin-Protein Ligases|Cell Cycle Proteins|Phosphorylation|SKP Cullin F-Box Protein Ligases|NF-kappa B|*WD40 Repeat|Ubiquitin-Conjugating Enzymes|GTP-Binding Proteins | |
10066784 J. Biol. Chem. 1999 Humans|Mice|Animals|loricrin|*Proline|*Membrane Proteins|transglutaminase 2|*Transglutaminases|transglutaminase 1|Amino Acid Sequence|Peptides|GTP-Binding Proteins|Circular Dichroism|Recombinant Proteins|Proline-Rich Protein Domains|Cornified Envelope Proline-Rich Proteins|Intermediate Filament Proteins|Epithelium|Cross-Linking Reagents | |
10067836 Endocrinology 1999 Cricetinae|Humans|Rats|Animals|*Glucagon-Like Peptide-1 Receptor|*Cricetulus|*CHO Cells|*Mitogen-Activated Protein Kinases|*G Proteins|Signal Transduction|Calcium-Calmodulin-Dependent Protein Kinases|Pertussis Toxin|INSR protein, human|Receptor, Insulin|Mitogen-Activated Protein Kinase 3|Enzyme Activation|Phosphorylation|Virulence Factors, Bordetella|MAP Kinase Signaling System|Insulin|Glucagon-Like Peptide 1|Antigens, CD | |
10067895 Nature 1999 PMC2323273 *Transforming Growth Factor beta|Wnt Proteins|Intercellular Signaling Peptides and Proteins|Bone Morphogenetic Proteins|Nodal Protein|Embryonic Induction|Zebrafish Proteins|Xenopus Proteins|Spemann Organizer|*Head|Endoderm|Signal Transduction|Proto-Oncogene Proteins|*Cytokines | |
10068651 Blood 1999 *B Cell Antigen Receptors|GAB1 protein, human|Adaptor Proteins, Signal Transducing|GAB2 protein, human|PTPN11 protein, human|Protein Tyrosine Phosphatase, Non-Receptor Type 11|Phosphoproteins|Signal Transduction|TYRP1 protein, human|*Membrane Glycoproteins|PI-3 Kinase|SH2 Domain-Containing Protein Tyrosine Phosphatases|Phosphorylation|*Growth Factor Receptors|SH2 Domains|*Cytokines|Protein Tyrosine Phosphatase, Non-Receptor Type 6|Interleukin 3 Receptor | |
10069808 Mol. Biol. Cell 1999 PMC25192 Animals|Humans|*Saccharomyces cerevisiae|*Glycosylphosphatidylinositols|*Endoplasmic Reticulum|Saccharomyces cerevisiae Proteins|Golgi Apparatus|*Yeast, Dried|Cell Surface Proteins|TYRP1 protein, human|Membrane Glycoproteins|Amino Acid Sequence|Sequence Homology, Amino Acid|Mannose|phosphorylethanolamine|Ethanolamines|Cell Wall|Biological Transport|Mutation | |
10069812 Mol. Biol. Cell 1999 PMC25196 Animals|*Chlamydomonas|*Cytoplasmic Dyneins|Dyneins|Flagella|Amino Acid Sequence|Microtubules|Sequence Homology, Amino Acid|Insertional Mutagenesis|Cloning, Molecular|Caenorhabditis elegans|Cytoplasm|Axonemes | |
10072071 Immunity 1999 Mice|Animals|*Neutrophils|rac Proteins|N-Formylmethionine Leucyl-Phenylalanine|rac1 GTP-Binding Protein|Superoxide|Mitogen-Activated Protein Kinases|Signal Transduction|F-Actin|Chemotaxis|Bone Marrow Cells|Hematopoietic Stem Cell Transplantation | |
10072072 Immunity 1999 Mice|Animals|cathepsin S|*Cathepsin B|invariant chain|Antigens, Differentiation, B-Lymphocyte|*Class II Major Histocompatibility Molecules|Antigen Presentation|Antigen Presenting Cells|Cathepsin L|*Germinal Center|protease S|*Peptides|T Cells | |
10072381 Genes Dev. 1999 PMC316502 Male|Female|Mice|Animals|Meiosis|*Synapsis, Chromosomal|Cell Cycle Proteins|Spermatocytes|MutL Homologs|Meiotic Prophase I|DNA-Binding Proteins|Nuclear Proteins|Chromosomes|Carrier Proteins|MutL Protein Homolog 1|Recombination, Genetic | |
10072384 Genes Dev. 1999 PMC316510 Animals|*Phosphorylation|*Active Transport, Cell Nucleus|Rel protein, Drosophila|*Drosophila Proteins|*Transcription Factors|Drosophila|DNA-Binding Proteins|Nuclear Proteins|Drosophila melanogaster|Phosphoproteins|Cell Nucleus|Signal Transduction Pathway|Serine|Embryo, Nonmammalian|Amino Acid Sequence|Mutation|Cytoplasm | |
10072434 Hum. Mol. Genet. 1999 Humans|Systemic carnitine deficiency|*Carnitine|Solute Carrier Family 22 Member 5|*Hyperammonemia|*Muscular Diseases|*Cardiomyopathy|*Mutations|Organic Cation Transport Proteins|Missense Mutation|*Biological Transport|Membrane Proteins|Point Mutation|Base Sequence|Amino Acid Sequence|Heterozygote|cDNA|Cations | |
10072481 J. Immunol. 1999 Humans|*Adaptor Proteins, Signal Transducing|*NK Cells|*Cytotoxicity, Immunologic|Carrier Proteins|Phosphoproteins|Phospholipase C gamma|Lymphocyte Activation|FCGR3B protein, human|Fc gamma RIII|Phosphorylation|Membrane Proteins|Phosphotyrosine|Signal Transduction|FCGR3A protein, human|Tyrosine|GPI-Linked Proteins|LAT protein, Human herpesvirus 2|Viral Proteins | |
10073940 Science 1999 Animals|*Drosophila|*Axin Protein|D protein, Drosophila|Drosophila Proteins|*Signal Transduction|CTNNB1 protein, human|beta Catenin|Wnt1 Protein|Armadillo Domain Proteins|Trans-Activators|Transcription Factors|Drosophila melanogaster|Adaptor Proteins, Signal Transducing|Proto-Oncogene Proteins|Repressor Proteins|Homeodomain Proteins|Body Patterning|Carrier Proteins | |
10074426 Curr. Biol. 1999 *Uracil-DNA Glycosidase|Base Excision Repair|N-Glycosyl Hydrolases|*Cloning, Molecular|Amino Acid Sequence|Substrate Specificity|DNA Damage|Protein Conformation|Sequence Homology, Amino Acid|DNA|Models, Molecular|Escherichia coli | |
10074428 Curr. Biol. 1999 Humans|Mice|Animals|Endothelial Cells|TNFRSF18 protein, human|*Glucocorticoid-Induced TNFR-Related Protein|TNFSF18 protein, human|Tumor Necrosis Factor Receptor|*Tumor Necrosis Factor-alpha|TRAF2|Receptors, Nerve Growth Factor|Amino Acid Sequence|T Cells|Lymphocyte Activation|NF-kappa B|mRNA|NF-kappa B kinase|Protein-Serine-Threonine Kinases|Apoptosis|Sequence Homology, Amino Acid | |
10075656 J. Biol. Chem. 1999 *PPAR gamma|EP300 protein, human|*E1A-Associated p300 Protein|CREBBP protein, human|CREB-Binding Protein|Trans-Activators|*Ligands|Nuclear Proteins|Transcription, Genetic|Activation, Transcriptional|Histone Acetyltransferases|Gene Expression Regulation|Thiazolidinediones|Rosiglitazone|Binding Sites|Nuclear Receptor Coactivator 1|Transfection | |
10075690 J. Biol. Chem. 1999 Humans|NFKBIA protein, human|*NF-KappaB Inhibitor alpha|*beta-Transducin Repeat-Containing Proteins|*Proteasome Endopeptidase Complex|I kappa B Proteins|NF-kappa B|*F-Box Proteins|DNA-Binding Proteins|Cullin Protein|Ubiquitins|Phosphorylation|SKP Cullin F-Box Protein Ligases|Cell Cycle Proteins|E3 Ubiquitin Ligase|GTP-Binding Proteins|Amino Acid Sequence|Peptide Synthases | |
10075700 J. Biol. Chem. 1999 *Calmodulin|adenylyl cyclase 8|*Adenylyl Cyclases|*Binding Sites|Cyclic AMP|*Protein Binding|Calcium|*Calcium Signaling|Amino Acid Sequence|Mutagenesis, Site-Directed|Kinetics | |
10075701 J. Biol. Chem. 1999 Animals|Rabbits|*p21-Activated Kinases|*Phosphorylation|Cell Cycle Proteins|Enzyme Activation|cdc42 GTP-Binding Protein|Amino Acid Sequence|Protein Binding|Peptide Mapping|Phosphopeptides|Cell Line|Histone|Protein Isoforms | |
10075717 J. Biol. Chem. 1999 Animals|*Hedgehog Proteins|*Zinc Finger Protein GLI1|Transcription Factors|Trans-Activators|Zinc Finger Protein Gli3|Repressor Proteins|Zinc Finger Protein Gli2|Kruppel-Like Transcription Factors|Xenopus Proteins|Nerve Tissue Proteins|Oncogene Proteins|Nuclear Proteins|*Promoter Regions, Genetic|Embryonic Induction|Zinc Fingers|Gene Expression Regulation, Developmental|Drosophila|Signal Transduction | |
10075721 J. Biol. Chem. 1999 Humans|Animals|Mice|*Amino Acid Sequence|*Guanine Deaminase|Base Sequence|Cloning, Molecular|cDNA|Polymerase Chain Reaction|DNA-spermidine|DNA|Sequence Alignment|cDNA Library|Open Reading Frame|Sequence Homology, Amino Acid|Escherichia coli|Spermidine | |
10075724 J. Biol. Chem. 1999 *trans-Golgi Network|*Furin|*Transcription Factor AP-1|Golgi Apparatus|Endosomes|Subtilisins|Plasma Membrane|Phosphorylation|Endocytosis|Membrane Proteins|Adaptor Proteins, Vesicular Transport|Adaptor Protein Complex alpha Subunits|Membrane Glycoproteins|Casein Kinase II|*Protein Transport|Amino Acid Sequence | |
10075733 J. Biol. Chem. 1999 Cattle|Animals|*Stargardt Disease|*Hydrolysis|*ATP-Binding Cassette Transporters|13-cis-retinal|Retinaldehyde|Rod Outer Segments|Retinoids|ATPase|Rod Photoreceptor|*Retina|Macular Degeneration|Adenosine Triphosphate|Binding Sites|*Biochemical Phenomena|ABCB1 protein, human|ATP Binding Cassette Transporter, Subfamily B | |
10077652 Proc. Natl. Acad. Sci. U.S.A. 1999 PMC15910 Pregnancy|Female|Humans|*Pregnancy-Associated Plasma Protein-A|Insulin-Like Growth Factor Binding Protein 4|*Fibroblasts|Metalloendopeptidases|Osteoblasts|Cells, Cultured|Media, Conditioned|Insulin-Like Growth Factor II|*Metalloproteases|Protein Binding|Blood Proteins|Molecular Weight|*Biochemical Phenomena|Mass Spectrometry|Antibodies | |
10078208 Mol. Cell 1999 Humans|*Hydrolysis|G-T mismatch-binding protein|*DNA-Binding Proteins|*DNA|MutS Homolog 2 Protein|MutS DNA Mismatch-Binding Protein|DNA Repair|Base Pair Mismatch|Adenosine Diphosphate|Adenosine Triphosphatases|Escherichia coli Proteins|Adenosine Triphosphate|Protein Binding|Mismatch Repair|Kinetics | |
10079109 J. Clin. Invest. 1999 PMC408153 Humans|*Protease Activated Receptor 1|*Thrombin|*Blood Platelets|Receptors, Thrombin|Platelet Aggregation|Platelet Activation|Platelet Aggregation Inhibitors|Adenosine Diphosphate|Antithrombotic Agents|Calcium|Signal Transduction | |
10079256 Am. J. Pathol. 1999 PMC1866435 Humans|*Ligands|Phylogeny|JAG2 protein, human|Jagged-2 Protein|JAG1 protein, human|Jagged-1 Protein|Serrate-Jagged Proteins|Intercellular Signaling Peptides and Proteins|Membrane Proteins|Calcium-Binding Proteins|Receptors, Notch|Intracellular Signaling Peptides and Proteins|Receptor, Notch1|Protein Binding|Signal Transduction|Cell Differentiation|In Situ Hybridization | |
10080182 Nat. Genet. 1999 Humans|Lysinuric Protein Intolerance|SLC7A7 protein, human|*Fusion Regulatory Protein 1, Light Chains|*Amino Acid Metabolism, Inborn Errors|Mutations|Amino Acid Transport Systems, Basic|Allele|Carrier Proteins|Homozygote|Biological Transport|Lysine|Plasma Membrane|Finland|LAT protein, Human herpesvirus 2|Viral Proteins|LAT protein, human|Membrane Proteins|Adaptor Proteins, Signal Transducing | |
10080183 Nat. Genet. 1999 Humans|Lysinuric Protein Intolerance|*Amino Acid Metabolism, Inborn Errors|Amino Acids|DNA Mutational Analysis|Amino Acid Transport Systems, Basic|Transporters, Amino Acid|Lysine|Carrier Proteins|Amino Acid Sequence|Mutation|Membrane Proteins|Allele|Genetic Linkage|Finland|Italy|SLC7A7 protein, human|Fusion Regulatory Protein 1, Light Chains | |
10080186 Nat. Genet. 1999 Humans|Imerslund-Grasbeck syndrome|intrinsic factor-cobalamin receptor|*Intrinsic Factor|*Anemia, Megaloblastic|*Vitamin B 12 Deficiency|*Proteinuria|*Receptors, Cell Surface|*Malabsorption Syndromes|*Mutations|Vitamin B12|Membrane Proteins|Amino Acid Sequence|Chromosome Mapping|Finland|Norway | |
10080941 Biochem. Biophys. Res. Commun. 1999 CTNNB1 protein, human|*beta Catenin|*Transcription Factor 7-Like 2 Protein|Transcription Factors|*Protein Binding|CDH1 protein, human|Cadherins|DNA-Binding Proteins|Trans-Activators|Binding Sites|Lymphoid Enhancer-Binding Factor 1|Adenomatous Polyposis Coli Protein|Amino Acid Sequence|Antigens, CD | |
10082512 Mol. Cell. Biol. 1999 PMC84039 Animals|IRF3 protein, human|*Interferon Regulatory Factor-3|*Transcriptional Activation|Phosphorylation|Trans-Activators|Cytoplasm|Cell Nucleus|Threonine|Promoter Regions, Genetic|Serine|Amino Acid Sequence|Mutation | |
10082553 Mol. Cell. Biol. 1999 PMC84080 Humans|transcription factor UBF|*TATA-Box Binding Protein|*DNA, Ribosomal|*Phosphorylation|*Pol1 Transcription Initiation Complex Proteins|RNA Polymerase I|DNA Binding Protein|Transcription, Genetic|*Promoter Regions, Genetic|Transcription Factors|Transcription Factor TFIID|TATA-Binding Protein Associated Factors|TATA Box|Protein Binding|RNA, Ribosomal|Activation, Transcription | |
1008494 Ann. Clin. Res. 1976 Rats|Animals|*Hemopexin|*Haem|protoporphyrin IX|Protoporphyrins|Porphyrins|coproporphyrin I|Coproporphyrins|Circular Dichroism|Tertiary Protein Structure|Protein Conformation|Protein Binding|Biological Transport|Binding Site|Liver | |
10085068 J. Biol. Chem. 1999 Humans|Animals|prenyl|RCE1 protein, human|Saccharomyces cerevisiae|*Neoprene|Saccharomyces cerevisiae Proteins|Prenylation, Protein|Metalloendopeptidases|Amino Acid Sequence|Proprotein Convertases|Membrane Proteins|Proteases|Peptides|Substrate Specificity|*Mammals|Cloning, Molecular | |
10085069 J. Biol. Chem. 1999 Mice|Animals|Saccharomyces cerevisiae|Prenylation, Protein|Saccharomyces cerevisiae Proteins|Metalloendopeptidases|ras Proteins|Amino Acid Sequence|Proprotein Convertases|Membrane Proteins|Methylation|Fibroblasts|Cells, Cultured | |
10085077 J. Biol. Chem. 1999 Humans|Rats|Animals|Vascular Endothelial Growth Factor A|*Endothelial Cells|TNFSF12 protein, human|*Cytokine TWEAK|*Neovascularization, Pathologic|Vascular Endothelial Growth Factors|Neovascularization, Physiologic|Endothelium, Vascular|Apoptosis Regulatory Proteins|*Morphogenesis|Cultured Cells|Growth Factors|Carrier Proteins|Recombinant Proteins|Cell Movement|Cell Division|Apoptosis|Tumor Necrosis Factor-alpha | |
10085079 J. Biol. Chem. 1999 Male|Animals|Humans|Rats|glutamate carboxypeptidase|dipeptidase|*Dipeptidases|*Dipeptidyl Peptidase 4|In Situ Hybridization, Fluorescence|FOLH1 protein, human|Glutamate Carboxypeptidase II|*Carboxypeptidases|Antigens, Surface|glucarpidase|*gamma-Glutamyl Hydrolase|cDNA|Cloning, Molecular|Base Sequence|Northern Blot|Amino Acid Sequence|Neuropeptide|Transfection | |
10085124 J. Biol. Chem. 1999 Humans|*cPLA2 alpha|*Cloning, Molecular|*Phospholipases A2, Cytosolic|Phospholipases A2|Northern Blots|Amino Acid Sequence|cDNA|mRNA|Cytosol|Binding Site|RNA Splicing|Phosphorylation|Sequence Homology, Amino Acid|Cell Line | |
10085237 Biochem. J. 1999 PMC1220137 Rats|Animals|*CCAAT Enhancer Binding Protein|*Cyclic AMP Response Element-Binding Protein|*Activating Transcription Factors|DDIT3 protein, human|Transcription Factor CHOP|Promoter Regions, Genetic|Transcription, Genetic|Nuclear Proteins|Gene Expression Regulation|Transcriptional Activation|Binding Sites|Base Sequence|ATF2 protein, human|Activating Transcription Factor 2|mRNA|C EBPbeta|arsenite|Arsenites | |
10087012 J. Pharmacol. Exp. Ther. 1999 Animals|Humans|*Jurkat Cell|*sigma Receptor|Pentazocine|Haloperidol|cDNA|Binding Site|Amino Acid Sequence|Binding, Competitive|Splicings, Alternative|Cloning, Molecular|RNA, Messenger|Ligands|Progesterone | |
10087200 Genomics 1999 Mice|Humans|Rats|Animals|multiple inositol-polyphosphate phosphatase|*Histidine|In Situ Hybridization, Fluorescence|Sequences, Amino Acid|PTEN protein, human|PTEN Phosphohydrolase|Base Sequence|Blotting, Northern|Chromosome Mapping|Endoplasmic Reticulum|inositol pentaphosphate|Inositol Phosphates|Sequence Homology, Amino Acid|Proteins|Inositol Hexakisphosphate|Growth Plate|Cell Differentiation|*Biological Phenomena | |
10089216 Glycobiology 1999 Humans|*Glycosylphosphatidylinositols|N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase|*Amidohydrolases|N-acetylglucosaminylphosphatidylinositol|Phosphatidylinositol|*Trypanosomes|Mannosyltransferases|Trypanosoma brucei brucei|Substrate Specificities|Acetylglucosamine|Inositol|HeLa Cells|*Lipogenesis|System, Cellfree|Molecular Conformation | |
10089880 Cell 1999 UBE2N protein, human|*Ubiquitin-Conjugating Enzymes|*Polyubiquitin|*DNA Repair|Saccharomyces cerevisiae|Saccharomyces cerevisiae Proteins|Ubiquitin|Ubiquitin-Protein Ligases|DNA Damage|Protein Binding|Binding Sites|Amino Acid Sequence|Lysine | |
10090333 Acta Physiol. Scand. 1999 Humans|*Carbonic Anhydrase IV|carbonic anhydrase VI|Carbonic Anhydrases|Carbonic Anhydrase Inhibitors|Ethoxzolamide|Carbonic Anhydrase II|*Erythrocytes|Anion Exchange Protein 1, Erythrocyte|Erythrocyte Membrane|Bicarbonates|Cells, Cultured | |
10092231 Science 1999 Humans|*Myosin-Light-Chain Kinase|PAK1 protein, human|*p21-Activated Kinases|*Phosphorylation|HeLa Cells|Myosin Regulatory Light Chain|rho-Associated Kinases|Cytoskeleton|Actin|Myosin II|rhoA GTP-Binding Protein|Signal Transduction|rac GTP-Binding Proteins|Cytoskeletal Proteins | |
10092233 Science 1999 Humans|Animals|CTNNB1 protein, human|*beta Catenin|*Protein Phosphatase 2|APC protein, human|Adenomatous Polyposis Coli Protein|*Signal Transduction|Axin Protein|Wnt Proteins|Trans-Activators|Xenopus laevis|Repressor Proteins|Xenopus Proteins|Phosphorylation|Glycogen Synthase Kinases|Calcium-Calmodulin-Dependent Protein Kinases|Zebrafish Proteins|Proto-Oncogene Proteins | |
10092508 Biochem. Biophys. Res. Commun. 1999 Humans|Male|LCAT protein, human|*Phosphatidylcholine-Sterol O-Acyltransferase|*Lysophospholipase|Amino Acid Sequence|Liver|*Phospholipases A2, Cytosolic|Recombinant Proteins|Lipoproteins|Cloning, Molecular | |
10092594 J. Biol. Chem. 1999 Humans|*Saccharomyces cerevisiae|Peroxisomes|*Yeast, Dried|Amino Acid Sequence|Palmitoyl-CoA Hydrolase|Base Sequence|Sequence Alignment|Microbodies|Cloning, Molecular|Substrate Specificity|Thiolester Hydrolases|Green Fluorescent Proteins|Acids, Fatty|Oleate|Lipid Metabolism | |
10092647 J. Biol. Chem. 1999 PMC3715997 Humans|*Alternative Splicing|*Group VI Phospholipases A2|*mRNA|*Exon|*Pancreatic Islets|*Isoforms|Amino Acid Sequence|cDNA|Base Sequence|cDNA Library|Phospholipases A2|*Chromosome Structures|*Chromosome 1|Cloning, Molecular|Insulinoma|6-(bromomethylene)tetrahydro-3-(1-naphthaleneyl)-2H-pyran-2-one|Pyrones|*Catalysis | |
10092778 J. Immunol. 1999 Mice|Animals|*Antigen Processing|invariant chain|Histocompatibility Antigens Class II|*Phagosomes|Antigens, Differentiation, B-Lymphocyte|*Genes, MHC Class II|*Peptides|Plasma Membrane|Macrophages|T Cells | |
10092818 J. Immunol. 1999 Humans|*Receptors, Formyl Peptide|*Neutrophils|*Monocytes|IL10 protein, human|*Interleukin-10|N-Formylmethionine Leucyl-Phenylalanine|Chemotaxis, Leukocyte|C5a, Complement|Receptors, Immunologic|platelet activating factor receptor|Platelet Membrane Glycoproteins|Cytokines|Flow Cytometry|Gene Expression|Gene Expression Regulation | |
10092863 Eur. J. Biochem. 1999 Humans|*Substrate Specificity|*Escherichia coli|Kinetics|Hybrid-B|*Recombinant Proteins|Uridine Diphosphate Galactose|Galactosyltransferases|Uridine Diphosphate|*Plasminogen Activators|N-Acetylgalactosaminyltransferases|Amino Acid Sequence|Recombinant Fusion Proteins|Catalysis|Models, Molecular|ABO Blood-Group System | |
10094192 Eur. J. Hum. Genet. 1999 Humans|*Fucosidosis|*Mutations|alpha-L-Fucosidase|Exon|DNA Mutational Analysis|Pedigree|Lysosomal Storage Diseases|Mutations, Missense|Codon|Polymerase Chain Reaction|Colorado|Italy|New Mexico|Cuba | |
10094313 RNA 1999 PMC1369773 *Ribonucleoproteins, Small Nucleolar|*RNA, Small Nucleolar|*Cell Nucleolus|Saccharomyces cerevisiae|Saccharomyces cerevisiae Proteins|Ribonucleoproteins, Small Nuclear|Pre-rRNA|fibrillarin|Chromosomal Proteins, Non-Histone|RNA Processing, Post-Transcriptional|Nuclear Proteins|18S RRNA|Transcription, Genetic|Protein Binding | |
10095107 Gene 1999 Male|Animals|Humans|Rats|*Phosphofructokinase-2|*Testis|*Fructose|*Kinase|Blotting, Northern|Phosphoric Monoester Hydrolases|Fructose-Bisphosphatase|Cloning, Molecular|cDNA Library|Amino Acid Sequence|mRNA|Isozymes|cDNA|Multienzyme Complexes|Glycolysis|Gene Expression Regulation, Enzymologic|PFKFB4 protein, human|Pfkfb4 protein, rat | |
10097073 Proc. Natl. Acad. Sci. U.S.A. 1999 PMC22330 Mice|Animals|FZD2 protein, human|Frizzled Proteins|Wnt Proteins|Xenopus Proteins|Receptors, G-Protein-Coupled|Drosophila|Xenopus laevis|Amino Acid Sequence|Signal Transduction|Proto-Oncogene Proteins|Binding Sites|Zebrafish Proteins|Drosophila Proteins|Membrane Proteins|Intracellular Signaling Peptides and Proteins | |
10097102 Proc. Natl. Acad. Sci. U.S.A. 1999 PMC22359 Animals|Chlorocebus aethiops|Humans|*beta-Arrestin|*Adrenergic Receptor, beta 2|HEK293 Cells|*Endocytosis|Clathrin|*beta-Arrestin 1|Clathrin-Coated Vesicles|Arrestins|*Signal Transduction|Membrane Proteins|Receptors, Cell Surface|Adaptor Protein Complex beta Subunits|Adaptors, Clathrin|Plasma Membrane|beta-Arrestin 2|COS Cells|Carrier Proteins|Isoproterenol | |
10097139 Proc. Natl. Acad. Sci. U.S.A. 1999 PMC22396 Humans|*Amyloid Precursor Protein Secretases|*Amyloid beta-Protein Precursor|*Disintegrins|Amyloid beta-Peptides|*Alzheimer Disease|HEK293 Cells|Aspartic Acid Endopeptidases|ADAM10 Protein|*Amyloid|ADAM Proteins|*Amyloidogenic Proteins|ADAM17 Protein|*Amyloidosis|Membrane Proteins|Golgi Apparatus|Protein Processing, Post-Translational|Amino Acid Sequence|Brain | |
10100195 Neurochem. Int. 1999 *Phosphatidylethanolamine N Methyltransferase|phosphatidylethanolamine|*Phosphatidylethanolamines|*Alzheimer Disease|Phosphatidyl Choline|Methylation|Methyltransferases|S-Adenosylmethionine|*Brain|Phospholipids|Magnesium|Kinetics|Hydrogen-Ion Concentration | |
10100623 FEBS Lett. 1999 Humans|Chlorocebus aethiops|Animals|Rats|*Receptors, Galanin|Iodine-125|*Iodine Radioisotopes|Galanin|Receptor, Galanin, Type 2|cDNA|Amino Acid Sequence|Nucleotide Sequence|Cloning, Molecular|Sequence Alignment|Receptors, G-Protein-Coupled|Sequence Homology, Amino Acid|PCR|Signal Transduction|Northern Blot|Cell, COS|Hypothalamus|Open Reading Frame | |
10101178 Genetics 1999 PMC1460565 Male|Mice|Animals|*Crossing Over, Genetic|MLH1 protein, human|*MutL Protein Homolog 1|*Synaptinemal Complex|Meiosis|Meiotic Prophase I|Spermatocytes|Nuclear Proteins|Adaptor Proteins, Signal Transducing|Recombination, Genetic|Carrier Proteins|Neoplasm Proteins|Heterochromatin | |
10101262 Biochim. Biophys. Acta 1999 bis(monoacylglyceryl)phosphate|*Phosphate|Lysophospholipids|Monoglycerides|*Acyltransferases|lysophosphatidylglycerol|Phosphatidylglycerols|Acylation|Macrophage|Cell Line|Acids, Fatty|Kinetics|Glycerol|Carbon-18|Carbon Radioisotopes | |
10101268 Biochim. Biophys. Acta 1999 Humans|*1-Phosphatidylinositol 4-Kinase|Amino Acid Sequence|Base Sequence|cDNA|Sequence Homology, Amino Acid|Cloning, Molecular|Wortmannin|Catalytic Domain|Kinetics|Brain | |
10102266 Cell 1999 Animals|*Axons|Nerve Tissue Proteins|Neurons|Intercellular Signaling Peptides and Proteins|Receptors, Immunologic|Spinal Cord|*Mammals|Neurogenesis|Gene Expression Regulation, Developmental|Brain|Signal Transduction | |
10102268 Cell 1999 Animals|*Axon Guidance|sli protein, Drosophila|Drosophila Proteins|roundabout protein|Nerve Tissue Proteins|Receptors, Immunologic|Drosophila|Axons|TYRP1 protein, human|*Membrane Glycoproteins|Neurogenesis|*Biological Evolution|Ligands|Cell Line | |
10102270 Cell 1999 Animals|*Hedgehog Proteins|Zinc Finger Protein GLI1|*Transcription Factors|Signal Transduction|Drosophila Proteins|Trans-Activators|Wings, Animal|Drosophila|Gene Expression Regulation, Developmental|DNA-Binding Proteins|Repressor Proteins|*Organogenesis | |
10102273 Cell 1999 *Proto-Oncogene Proteins c-akt|*Cell Survival|*Phosphorylation|Forkhead Box Protein O3|Proto-Oncogene Proteins|Phosphatidylinositol 3-Kinases|Forkhead Box Protein O1|Forkhead Transcription Factors|*Gene Expression Regulation|Signal Transduction|Apoptosis|Transcription, Genetic|CASP9 protein, human|Caspase 9|Fas Ligand Protein|Cell Nucleus|14-3-3 Proteins|Gene Activation | |
10102820 Science 1999 *Calcium-Calmodulin-Dependent Protein Kinase Type 2|*N-Methylaspartate|*Receptors, N-Methyl-D-Aspartate|*Hippocampus|*Neurons|Synapses|Phosphorylation|Green Fluorescent Proteins|Cells, Cultured|Protein Binding|Postsynaptic Density | |
10103005 Eur. J. Biochem. 1999 Animals|Cattle|Humans|In Situ Hybridization, Fluorescence|*Cloning, Molecular|dihydrolipoamide acyltransferase|Acyltransferases|Amino Acid Sequence|cDNA|glycine cleavage system|Multienzyme Complexes|Transferases|Base Sequence|Escherichia coli|Ligases|Branched-Chain 2-Oxo Acid Dehydrogenase|Carrier Proteins|Amino Acid Oxidoreductases|Blotting, Northern|Lipoic Acid|Sequence Homology, Amino Acid | |
10103054 Eur. J. Biochem. 1999 Humans|Iodine-125|*Iodine Radioisotopes|*Hep G2 Cells|*Ligands|acetyl-LDL|Lipoproteins, LDL|Scavenger Receptors, Class B|Cholesterol Esters|oxidized low density lipoprotein|CD36 Antigens|Lipoproteins, HDL|Receptors, Immunologic|*Biological Transport|Lipoproteins|Carrier Proteins|*Protein Transport|Binding, Competitive | |
10187770 J. Biol. Chem. 1999 Horses|Animals|*Caspase Activation and Recruitment Domain|BCL10 protein, human|*B-Cell CLL-Lymphoma 10 Protein|APAF1 protein, human|Apoptotic Protease-Activating Factor 1|CASP9 protein, human|Caspase 9|NF-kappa B|Amino Acid Sequence|Carrier Proteins|Caspases|Adaptor Proteins, Signal Transducing|CASP2 protein, human|Caspase 2|Signal Transduction|Sequence Homology, Amino Acid|Neoplasm Proteins|Apoptosis | |
10187838 J. Biol. Chem. 1999 Humans|*Chondroitin Sulfates|*Sulfates|*Cloning, Molecular|heparan-sulfate 2-sulfotransferase|*Sulfotransferases|UST protein, human|cDNA|Amino Acid Sequence|Base Sequence|Polymerase Chain Reaction|Blotting, Northern|Cell Line|Expressed Sequence Tag|Sequence Homology, Amino Acid | |
10187858 J. Biol. Chem. 1999 Humans|*SUMO Protein|ubiquitin-conjugating enzyme UBC9|Ubiquitin-Conjugating Enzymes|Ubiquitin-Activating Enzymes|Saccharomyces cerevisiae|Ubiquitins|Small Ubiquitin-Related Modifier Proteins|Saccharomyces cerevisiae Proteins|Recombinant Proteins|Ubiquitin-Protein Ligases|RANGAP1 protein, human|GTPase-Activating Proteins|Amino Acid Sequence|NFKBIA protein, human|I Kappa B-alpha Protein|Substrate Specificity|Sequence Homology, Amino Acid|SAE2 protein, S cerevisiae | |
10189370 J. Cell Biol. 1999 PMC2148210 Animals|Chlorocebus aethiops|*Golgi Apparatus|Microtubule-Associated Proteins|Microtubules|GOLPH3 protein, human|*Membrane Proteins|Centrosome|Tubulin|Cytoskeletal Proteins|*Protein Binding|Binding Protein|Nuclear Proteins|Amino Acid Sequence|*Chromosome Segregation|COS Cells|*Transcription Factors|Transfections | |
10190325 Hum. Genet. 1999 Humans|*Holocarboxylase Synthetase Deficiency|Carbon-Nitrogen Ligases|*Mutations|Biotin|cDNA|Polymorphism, Genetic|Sequence Analysis | |
10190331 Hum. Genet. 1999 Deafness, Autosomal Recessive 4|*Vestibular Aqueduct|Pendred syndrome|*Hearing Loss, Sensorineural|*Hearing Loss|Sulfate Transporters|*Deafness|*Mutations|Membrane Transport Proteins|Phenotype|*Syndromes|Pedigree|Homozygote|Heterozygote|Genotype|Carrier Proteins | |
10191087 Genomics 1999 Humans|*Neuroacanthocytosis|*DNA Mutational Analysis|*GTP-Binding Proteins|Exons|Acanthocytes|Introns|*Genomics|Amino Acid Sequence|Expressed Sequence Tags|Sequence Analysis, DNA|DNA, Complementary|In Situ Hybridization, Fluorescence|Mutation | |
10191093 Genomics 1999 Animals|Chlorocebus aethiops|Humans|*Neuraminidase|*Rodent|Amino Acid Sequence|Base Sequence|Cloning, Molecular|Blotting, Northern|DNA, Complementary|Binding Sites|Sequence Homology, Amino Acid|COS Cells|Intron|Transfection|Active Site|NEU2 protein, human | |
10191254 Biochem. J. 1999 PMC1220152 Dogs|Animals|*Gap Junction|DFNA3 protein, human|*Connexins|Connexin 26|GJA1 protein, human|Cx43|System, Cellfree|Cell Membrane|Microsomes|Ion Channels|Biological Transport|Golgi Apparatus|Liposomes | |
10191259 Biochem. J. 1999 PMC1220157 Humans|phosphatidylethanolamine|*Phosphatidylethanolamines|*Ethanolaminephosphotransferase|Saccharomyces cerevisiae|Cholinephosphotransferase|choline-ethanolaminephosphotransferase|*Transferases (Other Substituted Phosphate Groups)|*Lecithins|Phospholipids|Choline Kinase|CDP ethanolamine|Cytidine Diphosphate|1,2-diacylglycerol|Diacylglycerols|Substrate Specificity|Choline|CDP Choline|Ethanolamines | |
10191262 Biochem. J. 1999 PMC1220160 PDPK1 protein, human|*3-Phosphoinositide-Dependent Protein Kinases|*Glucocorticoids|AKT1 protein, human|Protein Kinase B|*Phosphatidylinositol 3-Kinase|Phosphorylation|Immediate-Early Proteins|PtdIns 3-Kinase|Substrate Specificity|Nuclear Proteins|Threonine|Protein Binding|Serine|Amino Acid Sequence|PtdIns|Transfection|IGF1 protein, human | |
10191299 J. Lipid Res. 1999 Cricetinae|Animals|Humans|*Monocytes|*Binding Proteins|CHO Cells|Endothelial Cells|Cricetulus|apolipoprotein B receptor|*Receptors, Lipoprotein|lipoprotein triglyceride|*Triglycerides|Apolipoprotein B 48|Macrophages|Apolipoproteins B|*Antibodies|Apo E|Membrane Proteins | |
10194437 Blood 1999 Humans|*Phosphorylation|*Phosphatidylinositol 3-Kinase|EPO protein, human|*Erythropoietin|*Protein Binding|Signal Transduction|SH2 Domain-Containing Protein Tyrosine Phosphatases|*Epoetin Alfa|GRB2 Adaptor Protein|Phosphoproteins|src Homology Domains|Shc Signaling Adaptor Proteins|Adaptor Proteins, Vesicular Transport|Protein Tyrosine Phosphatase, Non-Receptor Type 6|Phosphotyrosine|Phosphatidylinositol 3-Kinases|Src Homology 2 Domain-Containing, Transforming Protein 1|Protein Tyrosine Phosphatase, Non-Receptor Type 11 | |
10194441 Blood 1999 Humans|*Syntaxin 4|*Blood Platelets|*Phosphorylation|*Thrombin|SNAP25 protein, human|Synaptosomal-Associated Protein 25|Qc-SNARE Proteins|Vesicular Transport Proteins|Qb-SNARE Proteins|Syntaxin 1|R-SNARE Proteins|Protein Binding|Nerve Tissue Proteins|Exocytosis|Carrier Proteins|Membrane Fusion|Protein Kinase C|Amino Acid Sequence | |
10194451 Blood 1999 Humans|phosphatidylinositol 3,4,5-triphosphate|*Phosphorylation|*Tyrosine|*Phosphatidylinositol|Phosphatidylinositol Phosphates|*Phosphoric Monoester Hydrolases|*Leukemia, Myelogenous, Chronic, BCR-ABL Positive|SH3 Domain|Fusion Proteins, bcr-abl|*src Gene|Signal Transduction|GRB2 Adaptor Protein|Protein Binding|Phosphatidylinositol 3-Kinases|Amino Acid Sequence|INPP5D protein, human|Phosphatidylinositol-3,4,5-Trisphosphate 5-Phosphatases|*Collagen | |
10194514 J. Mol. Endocrinol. 1999 *Insulin|Sulfonylurea Receptors|Potassium Channels, Inwardly Rectifying|*Insulin, Regular, Human|Insulin Secretion|*Insulin-Secreting Cells|Islets of Langerhans|*Pancreas|Hyperinsulinism|Adenosine Triphosphate|Sulfonylurea Compounds|Glucose|KATP Channels|*Biological Transport | |
10195903 Science 1999 *Calcineurin|*Calcium|bcl-Associated Death Protein|bcl-X Protein|Apoptosis|Phosphorylation|*Cell Death|Proto-Oncogene Proteins c-bcl-2|Mitochondria|Neurons|Hippocampus|Carrier Proteins|Cytosol|14-3-3 Proteins|Tyrosine 3-Monooxygenase|Cell Survival | |
10196136 J. Biol. Chem. 1999 Animals|*Phosphorylation|*Glycogen Synthase Kinase 3 beta|*Axin Protein|*Glycogen Synthase|CTNNB1 protein, human|beta Catenin|Wnt Proteins|Adaptor Proteins, Signal Transducing|Repressor Proteins|Trans-Activators|Phosphoproteins|Calcium-Calmodulin-Dependent Protein Kinases|Amino Acid Sequence|Dishevelled Proteins|Signal Transduction|Zebrafish Proteins|Xenopus Proteins | |
10196172 J. Biol. Chem. 1999 Animals|Humans|*Cyclic GMP Dependent Protein Kinase|*Phosphorylation|*Serine|HEK293 Cells|Cyclic GMP|Large-Conductance Calcium-Activated Potassium Channels|Large-Conductance Calcium-Activated Potassium Channel alpha Subunits|Whole-Cell Recordings|Membrane Potentials|Nitroprusside, Sodium|Cyclic AMP-Dependent Protein Kinases|KT 5823|Carbazoles|Muscle Relaxation | |
10196183 J. Biol. Chem. 1999 Humans|transglutaminase 1|involucrin|*Transglutaminases|*Protein Precursors|Amino Acid Sequence|Recombinant Proteins|Membrane Proteins|Epidermis|Keratinocytes|Cornified Envelope Proline-Rich Proteins|Plasma Membranes|*Membranes|Glutamine|Substrate Specificity|Baculovirus|Kinetics | |
10196188 J. Biol. Chem. 1999 Animals|Humans|Rats|*Lysophospholipase|*Phospholipases A1|lysophosphatidylserine|*Phosphatidylserines|*Alternative Splicing|*Lysophospholipids|Phospholipases A|*Phospholipases A2, Cytosolic|phosphatidylethanolamine|Phosphatidylethanolamines|Amino Acid Sequence|Sequence Alignment|Base Sequence|Phosphatidyl Choline|Platelets|Substrate Specificity|cDNA | |
10196222 J. Biol. Chem. 1999 Humans|BDNF protein, human|*Brain-Derived Neurotrophic Factor|*Phosphorylation|FRS2 protein, human|tropomyosin-related kinase-B, human|Receptor, trkB|*Membrane Proteins|enovin|GRB2 protein, human|Growth Factor Receptor-Bound Protein-2|Signal Transduction|NTF3 protein, human|Mitogen-Activated Protein Kinases|Receptors, Nerve Growth Factor|Phosphoproteins|Receptor Protein-Tyrosine Kinases|Intracellular Signaling Peptides and Proteins|Calcium-Calmodulin-Dependent Protein Kinases | |
10196363 Hum. Mol. Genet. 1999 Male|Child, Preschool|Humans|Child|Anemia, sideroblastic spinocerebellar ataxia|*Cerebellar Ataxia|*Anemia, Sideroblastic|X-linked sideroblastic anemia|*Genetic Diseases, X-Linked|Spinocerebellar Ataxias|*Ataxia|Saccharomyces cerevisiae|*Mutation|Saccharomyces cerevisiae Proteins|ATP-Binding Cassette Transporters|Mitochondria|*Homeostasis|Iron | |
10197592 Cancer Res. 1999 Humans|Female|BRCA2 protein, human|*BRCA2 Protein|BRCA1 protein, human|*BRCA1 Protein|DNA Repair|Genes, BRCA1|Rad51 Recombinase|DNA-Binding Proteins|Breast Cancer, Familial|Breast Neoplasms|Transcription Factors|DNA Damage|Neoplasm Proteins|DNA Replication|Ovarian Cancer|DNA|RAD51 protein, human | |
10197979 Genes Dev. 1999 PMC316597 Animals|*Drosophila|*NF-kappa B|Drosophila Proteins|RELA protein, human|*Transcription Factor RelA|DNA-Binding Proteins|Drosophila melanogaster|Signal Transduction|Toll-Like Receptors|*Receptors, Immunologic|Nuclear Proteins|Genes, Insect|Receptors, Cell Surface|Phosphoproteins|Gene Expression Regulation|Membrane Glycoproteins|Antimicrobial Cationic Peptides|Immunity | |
10198061 Mol. Biol. Cell 1999 PMC25239 Animals|CTNNB1 protein, human|*beta Catenin|*Cell Nucleus|Karyopherins|ran GTP-Binding Protein|Nuclear Proteins|Cytoplasm|DNA-Binding Proteins|Cell Cycle Proteins|Importin-beta|Nuclear Import|Cytosol|Guanine Nucleotide Exchange Factors|Pores, Nuclear | |
10198158 Genomics 1999 Humans|Mice|Animals|*Cloning, Molecular|cDNA|Amino Acid Sequence|Intron|Base Sequence|Exons|Chromosome Mapping|Sequence Alignment|*Suprachiasmatic Nuclei|Blotting, Northern|mRNA|Genome|Open Reading Frame|In Situ Hybridization|Gene Expression|Sequence Analysis, DNA|Sequence Homology, Amino Acid|In Situ Hybridization, Fluorescence | |
10198162 Genomics 1999 Male|Humans|Mice|Animals|*DNA, Complementary|fructose-6-phosphate|*Glutamine|*Fructosephosphates|Cloning, Molecular|Amino Acid Sequence|Base Sequence|Sequence Alignment|Blotting, Northern|Glutamine-Fructose-6-Phosphate Transaminase (Isomerizing)|Chromosome Mapping|GFPT2 protein, mouse|Nitrogenous Group Transferases|Sequence Homology, Amino Acid|Sequence Analysis, DNA|RNA, Messenger|Tissue Distribution|Synteny | |
10198225 Biochem. Biophys. Res. Commun. 1999 Humans|*Interleukin-12 Receptor beta 2 Subunit|JAK2 protein, human|*Janus Kinase 2|IL12RB1 protein, human|Receptor, IL-12|*Cytoplasm|Phosphorylation|Signal Transduction|Receptors, Interleukin-3|*Cytoplasmic Membrane|IL12RB2 protein, human|Interleukin-3|Receptors, Interleukin-5|Protein Binding|Tyrosine|Amino Acid Sequence|DNA-Binding Proteins|Granulocyte-Macrophage Colony-Stimulating Factor | |
10198260 Biochem. Biophys. Res. Commun. 1999 Chlorocebus aethiops|Animals|Humans|Rats|long-chain-fatty-acid-CoA ligase|*Coenzyme A Ligases|lignoceric acid|*Fatty Acids|pristanic acid|Phytanic Acid|Endoplasmic Reticulum|Peroxisomes|Liver|COS-1 Cells|Amino Acid Sequence|Saccharomyces cerevisiae Proteins|Microbodies|Cloning, Molecular|Oxidation-Reduction|DNA, Complementary|Repressor Proteins|Transfection | |
10198291 J. Cell. Sci. 1999 *Furin|*Fibrillin|Fibrillin-1|Proprotein Convertases|Amino Acid Sequence|Subtilisins|Protein Processing, Post-Translational|Microfilament Proteins|Protein Precursors|Mutagenesis, Site-Directed|Extracellular Matrix Proteins|Fibroblasts|Extracellular Matrix | |
10198426 Am. J. Physiol. 1999 Rats|Animals|*Flounder|Sodium-Phosphate Cotransporter Proteins, Type II|Sodium-Phosphate Cotransporter Proteins|*Sodium|Symporters|Xenopus laevis|sodium phosphate|Phosphate|Oocytes|Isoforms|*Kidney|Membrane Potentials|Biological Transport|Kinetics|Hydrogen-Ion Concentration|*Biophysical Phenomena | |
10198631 Mol. Cell 1999 *Dyneins|BCL2 protein, human|Proto-Oncogene Proteins c-bcl-2|Apoptosis Regulatory Proteins|Bcl-2-Like Protein 11|Proto-Oncogene Proteins|Membrane Proteins|Carrier Proteins|Apoptosis|Amino Acid Sequence|Protein Structure, Tertiary|*Cytoskeleton|Protein Binding|Cell Line|Microtubule | |
10199400 Cell 1999 SMAD2 protein, human|Smad2 Protein|Homeodomain Proteins|Trans-Activators|Transcription Factors|SMAD4 protein, human|Smad4 Protein|TGFbeta|Repressor Proteins|Receptors, Transforming Growth Factor beta|Transcription, Genetic|TGFBR2 protein, human|Receptor, Transforming Growth Factor-beta Type II|Promoter Regions, Genetic|Activation, Transcriptional|Histone Deacetylases|Protein-Serine-Threonine Kinases|Signal Transduction | |
10199401 Cell 1999 *RNA Polymerase II|negative elongation factor|*Transcription Factors|P-TEFb|Transcriptional Elongation Factors|Transcription, Genetic|Nuclear Proteins|Repressor Proteins|Dichlororibofuranosylbenzimidazole|Protein-Serine-Threonine Kinases|Phosphorylation|RNA Binding Protein | |
10199779 J. Clin. Endocrinol. Metab. 1999 Humans|iodothyronine sulfotransferase|*Sulfotransferases|monoamine-sulfating phenol sulfotransferase|Arylsulfotransferase|Triiodothyronine|Diiodothyronines|Thyroid Hormones|Phosphoadenosine Phosphosulfate|Cytosol|Isoenzymes|Liver|Kidney|Sulfates|Substrate Specificities|Kinetics | |
10200320 Proc. Natl. Acad. Sci. U.S.A. 1999 PMC16390 Animals|Rats|Mice|9-deoxy-delta-9-prostaglandin D2|*Microglia|cyclopentenone|*Down-Regulation|*Prostaglandins B|NOS2 protein, human|*Inducible Nitric Oxide Synthase|15-deoxyprostaglandin J2|*Prostaglandin D2|*Cyclopentanes|NF-kappa B|Transcription Factors|Troglitazone|Nitric Oxide Synthase|Peroxisome Proliferator-Activated Receptor gamma|Gene Expression Regulation|Lipopolysaccharides|Astrocytes | |
10200466 Cell Death Differ. 1999 Humans|*Caspases|*Retinoblastoma Protein|APC protein, human|*Adenomatous Polyposis Coli Protein|alanine chloromethyl ketone|Amino Acid Chloromethyl Ketones|benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone|N-acetyl-tyrosyl-valyl-alanyl-aspartyl chloromethyl ketone|*Apoptosis|Caspase Inhibitors|Caspase 3|Poly ADP Ribose Polymerase|Cysteine Proteinase Inhibitors|Tumor Cells, Cultured | |
10201372 Nature 1999 Humans|CTNNB1 protein, human|*beta Catenin|CCND1 protein, human|*Cyclin D1|Transcription Factors|APC protein, human|Adenomatous Polyposis Coli Protein|TCF Transcription Factors|*Colon Cancer|Trans-Activators|DNA-Binding Proteins|Transcription, Genetic|Promoter Regions, Genetic|Genes, Adenomatous Polyposis Coli|CCNE1 protein, human|Oncogene Proteins|Gene Expression Regulation, Neoplastic|Signal Transduction | |
10201374 Nature 1999 Animals|*Wnt Proteins|*Protein A|Zebrafish Proteins|Signal Transduction|Zebrafish|Xenopus laevis|Drosophila|Proto-Oncogene Proteins|Mesoderm|Amino Acid Sequence | |
10201950 J. Immunol. 1999 Humans|lipopolysaccharide B|*Lipopolysaccharides|*Neutrophils|*Macrophage-1 Antigen|lipopolysaccharide-binding protein|Acute-Phase Proteins|Membrane Glycoproteins|Lipopolysaccharide Receptors|Monocytes|Antigens, Differentiation, Myelomonocytic|Carrier Proteins|Tumor Necrosis Factor-alpha|Antigens, CD|*Erythrocytes | |
10201980 J. Immunol. 1999 Animals|BTK protein, human|*Agammaglobulinaemia Tyrosine Kinase|*Phosphorylation|*Phosphatidylinositol 3-Kinase|*B Cell Activation Antigen|*Receptors, Antigen, B-Cell|Tyrosine Kinase, SYK|*Antigens, CD19|Protein-Tyrosine Kinases|*Adaptor Proteins, Signal Transducing|Signal Transduction|src-Family Kinases|Phospholipase C gamma|*Carrier Proteins|Intracellular Signaling Peptides and Proteins|Bruton type agammaglobulinemia|Agammaglobulinemia|B-Lymphocytes | |
10202141 EMBO J. 1999 PMC1171263 Humans|*GTPase Activating Protein|Saccharomyces cerevisiae Proteins|Rab6 protein|rab GTP-Binding Proteins|Saccharomyces cerevisiae|Amino Acid Sequence|Genes, Fungal|Schizosaccharomyces pombe|*Centrosome|ras GTPase-Activating Proteins|Base Sequence|Cloning, Molecular|Sequence Homology, Amino Acid | |
10202154 EMBO J. 1999 PMC1171276 Animals|*Transcriptional Activation|CREBBP protein, human|*CREB-Binding Protein|Nuclear Proteins|HIF1A protein, human|*Hypoxia-Inducible Factor 1, alpha Subunit|Trans-Activators|EP300 protein, human|*E1A-Associated p300 Protein|TXN protein, human|Thioredoxin|Cell Hypoxia|*Hypoxia|*Redox|APEX1 protein, human|DNA-(Apurinic or Apyrimidinic Site) Lyase|Amino Acid Sequence|Reporter Gene | |
10203854 Trends Neurosci. 1999 Fushi Tarazu Transcription Factors|Immediate-Early Proteins|Homeodomain Proteins|Luteinizing Hormone|Binding Sites|Early Growth Response Protein 1|Promoter Regions, Genetic|Steroidogenic Factor 1|Gonadotropin-Releasing Hormone|Muscle Spindle|Muscle Development | |
10205060 Science 1999 Humans|*Proteasome Endopeptidase Complex|*Heat Shock|Heat-Shock Proteins, HSP70|*mRNA Decay|Binding Protein|HSC70 Heat-Shock Proteins|Ubiquitins|Heat-Shock Proteins|EIF-4G|Messenger RNA|Ubiquitin|Poly A-Binding Protein|Transcription Factors|Leupeptins|Cysteine Proteinase Inhibitors|3' Untranslated Region|Cysteine Endopeptidases|HeLa Cells | |
10205168 EMBO J. 1999 PMC1171298 Chlorocebus aethiops|Animals|*Phosphorylation|*Serine|Proto-Oncogene Proteins c-raf|Genes, ras|Proto-Oncogene Proteins B-raf|Mitogen-Activated Protein Kinases|Tetradecanoylphorbol Acetate|COS Cells|*Proto-Oncogene Proteins|Mutations|Transfection|Tyrosine | |
10205180 EMBO J. 1999 PMC1171310 *Poly(A)-Binding Protein II|INS1 protein, influenza virus|*Viral Nonstructural Proteins|Pre-mRNA|Cleavage And Polyadenylation Specificity Factor|mRNA|RNA-Binding Proteins|Influenza A virus|Protein Binding|Binding Sites|Cell Nucleus | |
10206645 Nature 1999 Animals|*Amyloid Precursor Protein Secretases|*Presenilin-1|Amyloid beta-Protein Precursor|Aspartic Acid Endopeptidases|Presenilin-2|Receptors, Notch|Amyloid beta-Peptides|Alzheimer Disease|Transcription Factors|Receptor, Notch1|Signal Transduction|Peptide Fragments|Protein Binding|Ligands|Cell Line|Transfection | |
10206952 J. Biol. Chem. 1999 Humans|beta-galactoside alpha-2,3-sialyltransferase|*Sialyltransferases|*Glycolipids|lactosamine|*Amino Sugars|*Glycoproteins|*Cloning, Molecular|Amino Acid Sequence|Base Sequence|Substrate Specificity|cDNA|Sequence Homology, Amino Acid|Transfections | |
10206961 J. Biol. Chem. 1999 CASP9 protein, human|*Caspase 9|*Apoptosomes|*Cytochromes c|APAF1 protein, human|*Apoptotic Protease-Activating Factor 1|CASP3 protein, human|Caspase 3|Caspases|deoxyadenosine diphosphate|Deoxyadenine Nucleotides|Protein Binding|2'-deoxyadenosine triphosphate|Enzyme Activation|Apoptosis|Recombinant Proteins|Enzyme Precursors|Hydrolysis | |
10206966 J. Biol. Chem. 1999 Humans|Chlorocebus aethiops|Animals|*Sulfonylurea Receptors|Kir6.2 channel|Potassium Channels, Inwardly Rectifying|KATP Channels|Ion Channel Gating|Adenosine Triphosphate|Potassium Channel Blockers|Sulfonylurea Compounds|Membrane Potentials|Patch-Clamp Techniques|*Isoforms|COS Cells|Kinetics|Xenopus laevis | |
10206983 J. Biol. Chem. 1999 Humans|*Tyrosine Phosphatases, Protein|*Mitogen-Activated Protein Kinases|PTPN7 protein, human|Protein Tyrosine Phosphatases, Non-Receptor|*Signal Transduction|MAPK3 protein, human|Mitogen-Activated Protein Kinase 3|T-Cell Antigen Receptor|Phosphorylation|Intracellular Signaling Peptides and Proteins|Mitogen-Activated Protein Kinase 1|Protein Tyrosine Phosphatase, Non-Receptor Type 6|Substrate Specificity|Jurkat Cells|*Hematopoietic System|Protein-Tyrosine Kinases|Lymphocyte Activation|Transcription Factors | |
10207047 J. Biol. Chem. 1999 *src Homology Domains|myo-inositol-1 (or 4)-monophosphatase|GRB2 protein, human|*GRB2 Adaptor Protein|*Phosphoric Monoester Hydrolases|Receptors, Antigen, B-Cell|Phosphorylation|Protein Binding|Signal Transduction|Shc Signaling Adaptor Proteins|B-Lymphocytes|Tyrosine|Adaptor Proteins, Vesicular Transport|Src Homology 2 Domain-Containing, Transforming Protein 1 | |
10207050 Mol. Cell. Biol. 1999 PMC84119 *Phosphorylation|CDC2-CDC28 Kinases|E2F Transcription Factors|Retinoblastoma Protein|Retinoblastoma-Binding Protein 1|Cyclin-Dependent Kinase 2|Transcription Factor DP1|Cell Cycle|Cyclins|Cyclin E|Cyclin-Dependent Kinase 4|G1 Phase|Proto-Oncogene Proteins|S Phase|Cyclin-Dependent Kinase 6|E2F1 Transcription Factor | |
10207087 Mol. Cell. Biol. 1999 PMC84165 Mice|Animals|RUNX1 protein, human|*Core Binding Factor Alpha 2 Subunit|RUNX1 Translocation Partner 1 Protein|DNA-Binding Proteins|*Oncogenes|Proto-Oncogene Proteins|Promoter Regions, Genetic|Leukemia, Myeloid, Acute|Oncogene Proteins, Fusion|Translocation, Genetic|Hematopoiesis | |
10207098 Mol. Cell. Biol. 1999 PMC84199 Humans|*Receptors, Estrogen|*HSP90 Heat-Shock Proteins|*Signal Transduction|Molecular Chaperone|Saccharomyces cerevisiae|protein p23|DNA-Binding Proteins|Activation, Transcriptional|Oestradiol|Protein Binding|Receptors, Steroid|Binding Sites|Estrogens|Amino Acid Sequence | |
10207622 Biochem. Soc. Symp. 1999 *Phosphorylation|*Actins|*Mitogen-Activated Protein Kinase 11|Vascular Endothelial Growth Factor A|Endothelial Cells|HSPB1 protein, human|*Heat Shock Protein 27|Mitogen-Activated Protein Kinases|Calcium-Calmodulin-Dependent Protein Kinases|p38 Mitogen-Activated Protein Kinases|Enzyme Activation|Microfilament|Tyrosine Kinase|Cell Migration|Heat-Shock Proteins|Vascular Endothelial Growth Factors | |
10209023 J. Cell Biol. 1999 PMC2133115 prefoldin|*Cytoskeletal Proteins|Cytosolic Chaperonin|Protein Folding|Ribosome|Actin|Tubulin|Protein Binding|Protein Biosynthesis|Peptides|Adenosine Triphosphate | |
10209034 J. Cell Biol. 1999 PMC2133104 Humans|*Vascular Cell Adhesion Molecule-1|integrin alpha 9 beta 1|*Neutrophils|*Endothelial Cells|Integrin alpha4beta1|*Transendothelial Migration|Cell Adhesion|Chemotaxis, Leukocyte|alpha4 Integrin|CD18 Antigens|Cell Movement|Receptors, Lymphocyte Homing|Antigens, CD|Tenascin-C|Endothelium, Vascular|Osteopontin | |
10209122 Curr. Biol. 1999 Pregnancy|Female|Animals|Mice|*MAP Kinase Signaling System|Endothelial Cells|MAP2K1 protein, human|*MAP Kinase Kinase 1|MAP Kinase Kinase 2|Protein-Tyrosine Kinases|Protein-Serine-Threonine Kinases|*Placenta|Signal Transduction|Mitogen-Activated Protein Kinases|*Embryo Loss|*Ear, Inner|*Morphogenesis|*Neovascularization, Pathologic | |
10209123 Curr. Biol. 1999 Animals|Humans|macrogolgin|Golgins|Golgi complex autoantigen, 97-kDa|Golgi Apparatus|Autoantigens|Membrane Proteins|Protein Binding|Carrier Proteins|Protein Structure, Tertiary|Binding Sites|Amino Acid Sequence|Green Fluorescent Proteins|Splice Variants, Protein|Sequence Homology, Amino Acid|*Protein Domains|Mutations | |
10209961 Int. J. Cancer 1999 Humans|*Fibroblast Growth Factor|*Fibroblast Growth Factor 2|*Tumor Cell Lines|FGFR4 protein, human|Receptor, Fibroblast Growth Factor, Type 4|Receptor, Fibroblast Growth Factor, Type 2|Signal Transduction|mRNA|Cell Division|Phosphorylation | |
10212226 J. Biol. Chem. 1999 Humans|*UDP Galactose|*Acetylglucosamine|*Galactose|N-acetyllactosaminide alpha-1,3-galactosyltransferase|*Galactosyltransferases|Sialyl Lewis A Antigen|lacto-N-neotetraose|Oligosaccharides|Lewis Antigens|Sequences, Amino Acid|Transfection|DNA, Complementary|Pancreatic Cancer|*Pancreas|Cloning, Molecular|Colorectal Neoplasms | |
10212249 J. Biol. Chem. 1999 Animals|Humans|*Cystathionine gamma-Lyase|*Kinetics|Cystathionine|cystathionine beta-lyase|Lyases|L Cysteine|Cloning, Molecular|Escherichia coli|*Biochemical Phenomena|aminoethoxyvinylglycine|Glycine|propargylglycine|Alkynes | |
10212258 J. Biol. Chem. 1999 Humans|RAD52 protein, human|*Rad52 DNA Repair and Recombination Protein|Ataxia-Telangiectasia|*Genes, abl|RAD51 Protein|Cell Cycle Proteins|DNA Repair|DNA-Binding Proteins|Ataxia Telangiectasia Mutated Proteins|Tumor Suppressor Proteins|Phosphorylation|DNA Damage|Ionizing Radiation|Proto-Oncogene Proteins c-abl|Mutations|Recombination, Genetic|RAD51 protein, human|ATM protein, human | |
10215629 Genes Dev. 1999 PMC316641 Mice|Animals|*Osteogenesis|Osteoblasts|Core Binding Factor Alpha 1 Subunit|Cell Differentiation|Transcription Factors|Promoter Regions, Genetic|Bone Morphogenetic Protein 2|*Embryonic Development|Neoplasm Proteins|Transcriptional Activation|Osteocalcin|Transforming Growth Factor beta|Gene Expression Regulation, Developmental|Bone|Binding Sites|Mice, Transgenic|Cell Line | |
10215861 Eur. J. Biochem. 1999 Humans|alkylglycerone-phosphate synthase|*Peroxisomes|*Dihydroxyacetone Phosphate|glycerone-phosphate O-acyltransferase|*Acyltransferases|*Alkyl and Aryl Transferases|Transferases|Microbodies|Mitochondria, Liver|Liver|Intracellular Membranes|Phospholipids, Ether|Fibroblast|Hydrogen-Ion Concentration | |
10215863 Eur. J. Biochem. 1999 Humans|adenylate kinase 5|*Adenylate Kinase|*DNA, Complementary|*Recombinant Proteins|cytidylate kinase|Nucleoside-Phosphate Kinase|Cloning, Molecular|Amino Acid Sequence|Substrate Specificity|Sequence Alignment|Phosphorylation|Sequence Homology, Amino Acid|Cytosol|Blotting, Northern|Escherichia coli|DCMP protocol|Cytarabine|mRNA | |
10215864 Eur. J. Biochem. 1999 Animals|Humans|Cattle|OPRM1 protein, human|*Receptor, mu Opioid|*GTP-Binding Protein alpha Subunits, Gi-Go|Diprenorphine|Receptors, Opioid, kappa|Receptors, Opioid|Enkephalins|Etorphine|G Protein|Analgesics, Opioid|Binding, Competitive|*Isoforms|Guanylyl Imidodiphosphate | |
10217147 Nature 1999 Humans|Mice|Animals|AKT1 protein, human|*Proto-Oncogene Proteins c-akt|Phosphatidylinositol-3-OH Kinase|*Gene Expression Regulation|Phosphorylation|Signal Transduction|Proto-Oncogene Proteins|INSR protein, human|Insulin Receptor|Caenorhabditis elegans|3T3 Cells|Transfection|Antigens, CD|Forkhead Transcription Factors | |
10217420 FEBS Lett. 1999 Animals|Humans|*Receptors, Adrenomedullin|*Muscle, Smooth, Vascular|RAMP2 protein, human|Receptor Activity-Modifying Protein 2|RAMP1 protein, human|Receptor Activity-Modifying Protein 1|Receptor Activity-Modifying Protein 3|Calcitonin Receptor-Like Receptor|Receptor Activity Modifying Proteins|Receptors, Calcitonin|Adrenomedullin|GPR182 protein, human|*Receptors, G-Protein-Coupled|Intracellular Signaling Peptides and Proteins|Receptors, Peptide|Membrane Proteins|Calcitonin Gene-Related Peptide|Cyclic AMP | |
10218588 FEBS Lett. 1999 Humans|Male|kallikrein-related peptidase 3, human|*Prostate-Specific Antigen|Kallikreins|IGFBP3 protein, human|*Insulin-Like Growth Factor Binding Protein 3|Prostate|trypsin-like serine protease|Chymotrypsin|Electrophoresis, Polyacrylamide Gel|Amino Acid Sequence|Substrate Specificity|Peptides | |
10218944 Endocrinology 1999 Rats|Mice|Rabbits|Animals|*Growth Hormone|*Insulin Receptor Substrate Proteins|platelet protein P47|Phosphoproteins|*Human Growth Hormone|JAK2 protein, human|Janus Kinase 2|Phosphorylation|Receptors, Somatotropin|Transductions, Signal|Phosphotyrosine|Adaptor Proteins, Signal Transducing|*Pituitary Hormones, Anterior|Mitogen-Activated Protein Kinases|3T3 Cells|INSR protein, human|Insulin Receptor|STAT5 Transcription Factor | |
10219239 Cell 1999 ERG1 Potassium Channel|Long QT Syndrome|Ether-A-Go-Go Potassium Channels|*Arrhythmia, Cardiac|*Cardiac Conduction System Disease|Trans-Activators|Potassium|DNA-Binding Proteins|Transcriptional Regulator ERG|Cation Transport Proteins|Heart|Mutations, Missense|Cloning, Molecular | |
10219243 Cell 1999 *Actins|*Arp2-3 Complex|WASL protein, human|*Wiskott-Aldrich Syndrome Protein, Neuronal|Actin-Related Protein 3|Actin-Related Protein 2|Actin Cytoskeleton|Nerve Tissue Proteins|cdc42 GTP-Binding Protein|Signal Transduction Pathways|Phosphatidylinositol 4,5-Diphosphate|Protein Binding|Wiskott-Aldrich Syndrome|Binding Sites | |
10219247 Cell 1999 Humans|IL4 protein, human|*Interleukin-4|Interleukin 4 Receptor|IL4R protein, human|*Interleukin-4 Receptor alpha Chain|Protein Binding|Binding Sites|Amino Acid Sequence|IL15 protein, human|IL-15|Crystallography, X-Ray|Models, Molecular|Cytokine Receptor|IL2RG protein, human|Interleukin Receptor Common gamma Subunit|Signal Transduction|Proteins | |
10220111 J. Neurosci. Res. 1999 *Phosphorylation|Cyclic AMP Response Element-Binding Protein|*Axons|Cyclic AMP-Dependent Protein Kinases|Signal Transduction Pathway|bisindolylmaleimide|Indoles|Isoquinolines|*Cell Proliferation|Protein Kinase C|Blotting, Western|Sulfonamides|Cell Division|Protein Kinase Inhibitors|Dorsal Root Ganglion|Maleimides | |
10222061 Cell. Immunol. 1999 Humans|Animals|Mice|*Protein Kinase C-theta|Isoenzymes|Protein Kinase C|B Cells|Monocytes|Cell Line|Macrophages|Hematopoietic Stem Cell Transplantation | |
10224040 J. Biol. Chem. 1999 Humans|NOD1 protein, human|*Nod1 Signaling Adaptor Protein|*NF-kappa B|APAF1 protein, human|*Apoptotic Protease-Activating Factor 1|CASP9 protein, human|Caspase 9|Caspases|RELA protein, human|*Transcription Factor RelA|Adaptor Proteins, Signal Transducing|Signal Transduction|Apoptosis|Serine Threonine Kinase|Receptor-Interacting Protein Serine-Threonine Kinase 2|Amino Acid Sequence|Protein Kinases|Sequence Homology, Amino Acid | |
10224048 J. Biol. Chem. 1999 Animals|Humans|*Saccharomyces cerevisiae|synaptojanin|polyphosphoinositide phosphatase|*Phosphoric Monoester Hydrolases|*Nerve Tissue Proteins|Saccharomyces cerevisiae Proteins|phosphatidylinositol 3-phosphate|Phosphatidylinositol Phosphates|*Yeast, Dried|Phosphoinositides|phosphatidylinositol 4-phosphate|Golgi Apparatus|Actin|Inositol Phosphates|Phosphatidylcholine Transfer Protein|Protein Transport | |
10224102 J. Biol. Chem. 1999 Cricetinae|Animals|lipolysis-stimulated receptor|CHO Cells|Cricetulus|LDLR protein, human|*Low Density Lipoprotein Receptor|lipoprotein triglyceride|Triglycerides|Lipoproteins, VLDL|Chylomicrons|Lipoproteins|*Liver|Lipoproteins, LDL|Free Fatty Acids|Oleate|*Cloning, Molecular | |
10224103 J. Biol. Chem. 1999 *Phosphorylation|*Protein Conformation, alpha-Helical|*Cell Membrane|Proto-Oncogene Proteins c-kit|Receptor Protein-Tyrosine Kinases|Amino Acid Sequence|Mutagenesis, Site-Directed|*Cytoplasm|Signal Transduction|Tyrosine|Binding Sites|Phenylalanine | |
10224133 J. Biol. Chem. 1999 Humans|Mice|Animals|3'-nucleotidase|Lithium-3|*Lithium|*Inositol|inositol 1,4-bis(phosphate)|*Nucleotidases|nucleotidase|Phosphoric Monoester Hydrolases|*Radioisotopes|Saccharomyces cerevisiae|Amino Acid Sequence|Cloning, Molecular|Sodium|Magnesium|Recombinant Proteins|Adenosine Diphosphate|Sequence Homology, Amino Acid|cDNA | |
10224278 J. Exp. Med. 1999 PMC2193052 Humans|SLP-76 signal Transducing adaptor proteins|*Phosphoproteins|GRB2 protein, human|*GRB2 Adaptor Protein|*Signal Transduction|T Cell Receptor|SH2 Domain|Nuclear Proteins|DNA-Binding Proteins|Carrier Proteins|Jurkat Cells|Membrane Proteins|NFATC Transcription Factors|Phosphorylation|Protein Binding|Interleukine 2|Binding Sites|Amino Acid Sequence | |
10224290 J. Exp. Med. 1999 PMC2193067 Humans|Cricetinae|Mice|Animals|*Macrophages, Alveolar|Ferric Compounds|Receptors, Immunologic|Macrophages|Scavenger Receptors, Class A|Lung|Scavenger Receptors, Class B|Flow Cytometry|Antibodies, Monoclonal|Bronchoalveolar Lavage|cDNA|Marco protein, mouse | |
10224668 Int. J. Biochem. Cell Biol. 1999 Phospholipase C|*Second Messengers|Phospholipase D|Phospholipases A2|1,2-diacylglycerol|Diglycerides|Protein Kinase C|*Phospholipids|Signal Transduction Pathway|Phospholipases|Enzyme Activation|Arachidonic Acid|GTP-Binding Proteins|*Phagocytosis|Calcium|Exocytosis|Wortmannin | |
10225955 J. Cell Biol. 1999 PMC2185068 NECTIN1 protein, human|*Nectins|afadin|*Adherens Junctions|*Cell Adhesion|*PDZ Domains|*Microfilament Proteins|*Cell Adhesion Molecules|CDH1 protein, human|*E Cadherin|*Immunoglobulin|Myosins|Intercellular Junctions|Cell Lines|*Transcription Factors|poliovirus receptor|Receptors, Virus|Protein Binding | |
10227395 J. Med. Genet. 1999 PMC1734351 Humans|*Cytochrome P4501B1|*Roma|Slovakia|*Hydrophthalmos|Cytochrome P450|*Mutation|Homozygote|Founder Effect|Glaucoma 3, Primary Congenital, A|Glaucoma|Pedigree|Exon|Genetic Linkage|Chromosome Mapping|*Optic Nerve Diseases|PCR|Haplotype|Amino Acid Sequence | |
10228158 EMBO J. 1999 PMC1171326 Animals|*Drosophila|Origin Recognition Complex|Transcription Factors|Cell Cycle|Cell Cycle Proteins|Drosophila Proteins|E2F Transcription Factors|Retinoblastoma-Binding Protein 1|DNA Replication|Trans-Activators|*Cell Cycle Checkpoints|Cell Division|Carrier Proteins|Replication Origins|Binding Sites|Promoter Regions, Genetic|Cdc6 protein, Drosophila | |
10228164 EMBO J. 1999 PMC1171332 Humans|*Progestins|*Oestradiol|geldanamycin|Lactams, Macrocyclic|MAPK1 protein, human|Mitogen-Activated Protein Kinase 1|Signal Transduction|Benzoquinones|MAP2K1 protein, human|MAP Kinase Kinase 1|*Estrogens|Proto-Oncogene Proteins|Protein-Tyrosine Kinases|Receptors, Estradiol|*Activation, Transcriptional|Calcium-Calmodulin-Dependent Protein Kinases|*DNA Replication|Mitogen-Activated Protein Kinases | |
10228168 EMBO J. 1999 PMC1171336 *WW Domains|*Protein A|*Transcription Factors|DNA-Binding Proteins|Activation, Transcriptional|Transcription, Genetic|Phosphoproteins|Saccharomyces cerevisiae Proteins|Saccharomyces cerevisiae|Adaptor Proteins, Signal Transducing|Carrier Proteins|Protein Binding|Amino Acid Sequence|Cell Nucleus|Promoter Regions, Genetic|Mutation | |
10228171 EMBO J. 1999 PMC1171339 Animals|Humans|*Saccharomyces cerevisiae|*Active Transport, Cell Nucleus|HeLa Cells|Nucleocytoplasmic Transport Proteins|Nucleoporin|Saccharomyces cerevisiae Proteins|Pores, Nuclear|Cell Nucleus|*Yeast, Dried|Nuclear Proteins|RNA-Binding Proteins|mRNA|Cytoplasm|*RNA Transport|Amino Acid Sequence|Sequence Homology, Amino Acid | |
10228183 J. Gen. Physiol. 1999 PMC2222910 Animals|Humans|*Receptors, Purinergic P2X2|Kinetics|HEK293 Cells|Ion Channel Gating|Patch-Clamp Techniques|Membrane Potentials|Ion Channels|Receptors, Purinergic P2|Electrophysiology|Adenosine Triphosphate|Xenopus laevis|Oocytes|Proton|Embryo, Mammalian | |
10229672 Biochem. J. 1999 PMC1220235 *Fibrillin|*Matrix Metalloproteinases|Fibrillin-1|Microfibrils|Extracellular Matrix Proteins|Marfan Syndrome|Ectopia Lentis|Microfilament Proteins|Amino Acid Sequence|Protein Binding|Binding Sites|Elastic Tissue|Peptide Fragments | |
10229681 Biochem. J. 1999 PMC1220244 Humans|*Stearoyl-CoA Desaturase|*Polyadenylation|Introns|cDNA|Exon|Base Sequence|Chromosome Mapping|Cloning, Molecular|Sequence Alignment|Amino Acid Sequence|Blotting, Northern|PCR|Alternative Splicing|cDNA Library|RNA, Messenger|Genome, Human|RNA | |
10229797 J. Immunol. 1999 Mice|Humans|Animals|CC chemokine receptor 9|HEK293 Cells|*Receptors, CCR|CCL25 protein, human|*Chemokines, CC|*Chemokines|Chemotaxis|Spleen|Amino Acid Sequence|Cell Movement|Signal Transduction|Lymph Nodes | |
10230406 Mol. Cell 1999 Cullin 1|*Ubiquitin|*Cullin Proteins|NFKBIA protein, human|*IKappaBalpha|I-kappa B Proteins|*Ubiquitination|beta TrCP|Cell Cycle Proteins|SKP Cullin F-Box Protein Ligases|Ubiquitins|Ubiquitin-Protein Ligases|DNA-Binding Proteins|Phosphorylation|NF-kappa B|I-kappa B Kinase|Anaphase-Promoting Complex-Cyclosome|S-Phase Kinase-Associated Proteins | |
10231017 Exp. Mol. Med. 1999 Animals|*Epidermis|Keratinocytes|loricrin|Membrane Proteins|involucrin|Protein Precursors|Keratin|Cornified Envelope Proline-Rich Proteins|Intermediate Filament Proteins|Skin|Cytoskeletal Proteins|Cytoplasmic Membrane|Epithelium|transglutaminase 1|Transglutaminases|Ichthyoses | |
10231375 Eur. J. Biochem. 1999 Humans|Guinea Pigs|Animals|*Gap Junctions|connexin 32|Connexins|DFNA3 protein, human|*Plasma Membrane|Connexin 26|*Golgi Apparatus|Intracellular Membranes|Connexin 43|*Ion Channels|Endoplasmic Reticulum|*Liver|Biological Transport|Subcellular Fraction|HeLa Cells | |
10231530 Biochemistry 1999 Humans|*Catalysis|Models, Molecular|Protein Conformation|Crystallography, X-Ray|Binding Sites|3-Hydroxyacyl CoA Dehydrogenases|Amino Acid Sequence|Dimerization|Kinetics|Hydrogen-Ion Concentration|NAD|Static Electricity|3-Hydroxyacyl-CoA Dehydrogenase | |
10232633 Am. J. Clin. Nutr. 1999 *Vitamin A Deficiency|Retinol|RBP4 protein, human|Retinol-Binding Proteins, Plasma|Blindness, Night|*Mutations|Prealbumin | |
10233168 Mol. Biol. Cell 1999 PMC30487 Humans|*mRNA|8-hydroxyguanine|oxoguanine glycosylase 1, human|*DNA Glycosylases|*Splicings, Alternative|DNA-Formamidopyrimidine Glycosylase|*RNA Splicing|Guanine|DNA Repair|Cell Nucleus|Mitochondria|Amino Acid Sequence|Exons|DNA | |
10233885 Blood 1999 Humans|*Promoter Regions, Genetic|CCAAT-Enhancer-Binding Proteins|c-myb Protein|Activation, Transcriptional|Trans-Activators|Transcription, Genetic|Nuclear Proteins|Binding Sites|Gene Expression Regulation|Base Sequence|Isoforms|Transfection|C EBPbeta|Cell Line|*Protein Domains|DNA | |
10233995 J. Virol. 1999 PMC112577 *RNA, Viral|*Polyadenylation|*Stuttering|Poly A|mRNA|Influenza A virus|DNA-Directed RNA Polymerases|Virus Replication|Base Sequence|Transcription, Genetic|Orthomyxoviridae | |
10234000 J. Neurosci. 1999 PMC6782724 Animals|Humans|Infant, Newborn|*Opsin|*Rod Opsins|*Mammals|*Brain|Retina|Pineal Gland|Vertebrates|Amino Acid Sequence|Interneurons|Hypothalamus|Neurons|Phylogeny|Cerebellum|Sequence Homology, Amino Acid | |
10235266 Nature 1999 Mice|Animals|DRIP, VDR interacting protein complex|*Transcriptional Activation|*Ligands|*Mediator Complex|*Receptors, Nuclear|Transcription Factors|Nuclear Proteins|Trans-Activators|Chromatin|Transcription, Genetic|VDR protein, human|Vitamin D Receptor|Protein Binding|Amino Acid Sequence|Carrier Proteins | |
10318789 J. Biol. Chem. 1999 caspase-activated deoxyribonuclease|*Histones|*Deoxyribonucleases|DFFB protein, human|*Poly-ADP-Ribose Binding Proteins|CASP3 protein, human|Caspase 3|Caspases|DNA Fragmentation|Apoptosis Regulatory Proteins|Caspase-7|Amino Acid Sequence|*Endonucleases|Apoptosis|Caspase 6|Chromatin|Intracellular Signaling Peptides and Proteins|Molecular Chaperone | |
10318832 J. Biol. Chem. 1999 PMC3508791 Mice|Humans|Animals|Rats|*Ryanodine Receptor Calcium Release Channel|*Glucagon-Like Peptide 1|*Calcium|Diabetes Mellitus, Type 2|8-chloro-cyclic adenosine monophosphate|*8-Bromo Cyclic Adenosine Monophosphate|Pancreatic Islets|Glucagon|Ryanodine|Insulin|*Pancreatic beta Cells|Insulinoma|Insulin Secretion|*Cytoplasm|Cyclic AMP|Cyclic AMP-Dependent Protein Kinases|Calcium Signaling|Glucose | |
10318838 J. Biol. Chem. 1999 *ADP-Ribosylation Factor|lysyllysine|*COP-Coated Vesicles|Golgi Apparatus|beta COP|*Dipeptides|ADP-Ribosylation Factor 1|Intracellular Membranes|*Binding Site|Guanosine Triphosphate|Guanosine 5'-O-(3-Thiotriphosphate)|GTP-Binding Proteins|Cytosol|Microtubule-Associated Proteins|Membrane Proteins|Protein Binding|*Protein Domains|*Signal Transduction | |
10318916 Proc. Natl. Acad. Sci. U.S.A. 1999 PMC21892 CTNNB1 protein, human|*beta Catenin|*Genes, bcl-1|Transcription Factors|DNA-Binding Proteins|CCND1 protein, human|Cyclin D1|Trans-Activators|Lymphoid Enhancer-Binding Factor 1|Cadherins|Activation, Transcriptional|Transcription, Genetic|Promoter Regions, Genetic|Adenomatous Polyposis Coli Protein|Signal Transduction|Binding Site|Cell Nucleus|Colon Cancer | |
10318917 Proc. Natl. Acad. Sci. U.S.A. 1999 PMC21893 Cricetinae|Rats|Animals|*Sterol Esterase|CHO Cells|Cricetulus|FABP4 protein, human|*Adipocyte Lipid Binding Protein|Fatty Acid-Binding Protein 7|Neoplasm Proteins|Myelin P2 Protein|Nerve Tissue Proteins|Acids, Fatty|Binding Sites|Adipocytes|Mutagenesis, Site-Directed|Free Fatty Acids|Models, Molecular|Ligands | |
10318934 Proc. Natl. Acad. Sci. U.S.A. 1999 PMC21910 Humans|Male|Female|Mice|Animals|Bloom syndrome protein|*Replication Protein A|*Bloom Syndrome|*Spermatocytes|*Meiosis|*RecQ Helicases|*Cell Nucleus|Synaptinemal Complex|DNA Replication|Recombination, Genetic|Rad51 Recombinase|DNA Repair|DNA-Binding Proteins|DNA|*Chromosome Structures|Synapsis|Diplonema|*Mammals | |
10319328 Mol. Endocrinol. 1999 Mice|Animals|Humans|IRS2 protein, human|*Insulin Receptor Substrate Proteins|*Phosphorylation|Neoplasm Recurrence, Local|*Signal Transduction|*Estrogens|IGF1 protein, human|Insulin-Like Growth Factor I|Receptor, IGF Type 1|Mitogen-Activated Protein Kinases|Receptors, Estrogen|Phosphatidylinositol 3-Kinases|IGF1R protein, human|Receptors, Somatomedin|Phosphoproteins | |
10319874 Nat. Genet. 1999 Humans|*alpha-Synuclein|Neurodegenerative Diseases|HEK293 Cells|Lewy Bodies|*Inclusions, Cytoplasmic|Parkinson Disease|Carrier Proteins|Neurons|Substantia Nigra|Brain|*Cytosol|*Gene Expression|Cytoplasm|*Genes, Regulator|Transfection | |
10321728 Oncogene 1999 Humans|CACUL1 protein, human|CTNNB1 protein, human|*beta Catenin|*Phosphorylation|*I-kappa B Proteins|Cullin Proteins|betaTrCP|NF-kappa B|Cell Cycle Proteins|Ubiquitins|DNA-Binding Proteins|SKP Cullin F-Box Protein Ligases|E3 Ubiquitin Ligase|NF-KappaB Inhibitor alpha|UBB protein, human|Ubiquitin|GTP-Binding Proteins|S-Phase Kinase-Associated Proteins | |
10322410 Trends Endocrinol. Metab. 1999 *Glucagon-Like Peptide 2|Short Bowel Syndrome|Intestines|Glucagon-Like Peptide 1|Intestinal Mucosa|Peptides|Permeability | |
10323864 Genes Dev. 1999 PMC316956 Humans|*Active Transport, Cell Nucleus|mRNA|RNA, Viral|*RNA Transport|Cell Nucleus|Nuclear Localization Signals|*Gene Expression|Mason-Pfizer monkey virus|Base Sequence|Nuclear Proteins|Nucleic Acid Conformation|Amino Acid Sequence|Cell Line | |
10323868 Genes Dev. 1999 PMC316946 Humans|*Phosphorylation|*Cyclin-Dependent Kinases|CDK2 protein, human|Cyclin-Dependent Kinase 2|Cyclin|CDKN1B protein, human|Cyclin-Dependent Kinase Inhibitor p27|CDC2-CDC28 Kinases|CCNE1 protein, human|Cyclin E|Cell Cycle|G1 Phase|*Ubiquitination|Cyclin-Dependent Kinase Inhibitor p21|Microtubule-Associated Proteins|Cyclin A|Proliferating Cell Nuclear Antigen|Cell Division | |
10327278 Curr. Opin. Lipidol. 1999 Humans|Animals|Mice|*Acids, Fatty|*Oxidation-Reduction|Acyl-CoA Dehydrogenase|*Mitochondria|Lipid Metabolism, Inborn Errors|Fatty Acid Desaturases|Carnitine O-Palmitoyltransferase|Electron Transport|Carnitine|Acetyl Coenzyme A | |
10329026 Mol. Genet. Metab. 1999 Humans|retinol dehydrogenase|*Keratinocytes|*Alcohol Oxidoreductases|*Epidermis|Retinoic Acid|Vitamin A|Retinaldehyde|Receptor, Retinoic Acid|Blotting, Northern|HSD17B6 protein, human|*Racemases and Epimerases|Cloning, Molecular|DNA, Complementary|Cell Nucleus|Cell Differentiation | |
10329152 J. Mol. Biol. 1999 Humans|leukotriene-C4 synthase|*Lipid Peroxidation|glutathione S-transferase alpha|*Glutathione Transferase|*Catalysis|Isoenzymes|Protein Conformation|Binding Site|Substrate Specificity|Amino Acid Sequence|*Mutagenesis|Models, Molecular|Kinetics|Crystallography, X-Ray|Glutathione|Mutagenesis, Site-Directed|Hydrophobic and Hydrophilic Interactions | |
10329163 J. Mol. Biol. 1999 Humans|*Phenylalanine-tRNA Ligase|tRNAPhe|*Mitochondria|Base Sequence|Amino Acyl-tRNA Synthetases|Amino Acid Sequence|Saccharomyces cerevisiae|Binding Sites|Escherichia coli|Nucleic Acid Conformation|Sequence Homology, Amino Acid|Genetic Evolution | |
10329413 Biochem. Biophys. Res. Commun. 1999 *Replication Protein C|*Telomere|Proliferating Cell Nuclear Antigen|DNA Replication|Homeodomain Proteins|DNA Polymerase delta|Repressor Proteins|Saccharomyces cerevisiae Proteins|Protein Binding|Minor Histocompatibility Antigens|cDNA|DNA Primers|Proto-Oncogene Proteins c-bcl-2|Recombinant Fusion Proteins | |
10329428 Biochem. Biophys. Res. Commun. 1999 Male|Humans|Animals|Mice|Sodium-Phosphate Cotransporter Proteins|*Ion Transport|cDNA|*Intestine, Small|Amino Acid Sequence|Northern Blot|Symporters|Cloning, Molecular|Xenopus laevis|Biological Transport|Membrane Transport Proteins|Chromosome Mapping|Oocytes|Kidney|Sodium | |
10329646 J. Biol. Chem. 1999 CASP9 protein, human|*Caspase 9|*Nuclear Factor-Kappab|APAF1 protein, human|*Apoptotic Protease-Activating Factor 1|Receptor-Interacting Protein Serine-Threonine Kinase 2|Nod1 Signaling Adaptor Protein|Adaptor Proteins, Signal Transducing|Amino Acid Sequence|Caspases|Apoptosis|Signal Transduction|Protein Kinases|Sequence Homology, Amino Acid|Apoptosis Regulatory Proteins | |
10329687 J. Biol. Chem. 1999 Humans|Female|Pregnancy|Rats|Animals|In Situ Hybridization, Fluorescence|*Membrane Transport Proteins|biotin transporter|Symporters|*Sodium|*Placenta|Biotin|cDNA|Biological Transport|Membrane Glycoproteins|Cloning, Molecular|Choriocarcinoma|Pantothenic Acid|Amino Acid Sequence|Xenopus laevis|*Vitamin|*Chromosome Structures | |
10329733 J. Biol. Chem. 1999 TP53 protein, human|*Tumor Suppressor Protein p53|*Transcription Factor, Brn-3A|BCL2 protein, human|*Proto-Oncogene Proteins c-bcl-2|*Promoter Regions, Genetic|DNA-Binding Proteins|Transcription Factors|Binding Site|Apoptosis|Neurons|DNA|alpha-internexin|Intermediate Filament Proteins|Cell Line | |
10329961 Am. J. Physiol. 1999 *Glucosephosphate Dehydrogenase|Hydrogen Peroxide|*Oxidation-Reduction|*Cell Death|NADPH|Reactive Oxygen Species|Antioxidants|Glutathione|Apoptosis|Phosphorylation | |
10330143 Mol. Cell. Biol. 1999 PMC104362 Mice|Animals|*p38 Mitogen-Activated Protein Kinases|*MEF2 Transcription Factors|Mitogen-Activated Protein Kinases|Phosphorylation|Signal Transduction|jun-NH2-Terminal Kinase|Activation, Transcriptional|Calcium-Calmodulin-Dependent Protein Kinases|ets-Domain Protein Elk-1|MADS Domain Proteins|3T3 Cells|Substrate Specificity | |
10330172 Mol. Cell. Biol. 1999 PMC104391 Mice|Animals|ZFP36 protein, human|*Tristetraprolin|*Tumor Necrosis Factor-alpha|*mRNA|*AU Rich Elements|Zinc Fingers|DNA-Binding Proteins|Amino Acid Sequence|Transfection|Cell Line | |
10330177 Mol. Cell. Biol. 1999 PMC104396 Humans|Mice|Animals|*Heterochromatin|Transcription Factors|*Gene Silencing|DNA-Binding Proteins|Euchromatin|Nuclear Proteins|Repressor Proteins|Chromosomal Proteins, Non-Histone|Zinc Fingers|Tripartite Motif-Containing Protein 28|CDKN3 protein, human|*Cyclin-Dependent Kinase Inhibitor Proteins|Transcription, Genetic|Histones|*Dual-Specificity Phosphatases|Gene Activation|Cell Nucleus|Protein Binding | |
10330186 Mol. Cell. Biol. 1999 PMC104405 Humans|*Interphase|*Cytoplasm|cdc25 Phosphatases|Cyclin B1|Mitosis|CDC2 Protein Kinase|Cell Nucleus|*Binding Site|Export, Nuclear|Phosphorylation|*Cytosol|CDC25C protein, human | |
10330343 Am. J. Hum. Genet. 1999 PMC1377899 Humans|*Sialic Acid Storage Disease|UDP acetylglucosamine-2-epimerase|*Allosteric Site|RENBP protein, human|*Carbohydrate Epimerases|cytidine-5'-monophosphosialic acid|Sialic Acids|Cytidine Monophosphate N-Acetylneuraminic Acid|Sialic Acid|*Mutations|Heterozygote|Cytidine Monophosphate|Carrier Proteins|cDNA | |
10330415 J. Cell Biol. 1999 PMC2133194 Cricetinae|Animals|*L-Selectin|*Sulfotransferases|*Ligands|CHO Cells|Cricetulus|Carbohydrate Sequence|sulfated glycoprotein p50|Mucins|Fucosyltransferases|Lewis X Antigen|Sialomucins|*Endothelial Cell|Venules|Oligosaccharides|Cell Adhesion|Lymphocytes|Amino Acid Sequence|Glycosylation | |
10330422 J. Clin. Invest. 1999 PMC408448 *Leukemia, Promyelocytic, Acute|*Retinoids|CEBPE protein, human|*CCAAT-Enhancer-Binding Proteins|Retinoic Acid|Retinoic Acid Receptor alpha|Receptors, Retinoic Acid|Transcription Factor|Oncogene Proteins, Fusion|Cell Differentiation|Reporter Gene|Cell Line|Promoter Regions, Genetic | |
10331075 Annu. Rev. Pharmacol. Toxicol. 1999 COMT protein, human|*Catechol O-Methyltransferase|thiopurine methyltransferase|*Histamine N-Methyltransferase|*Methylation|*Methyltransferases|Pharmacogenetics|Genetic Polymorphisms|Inactivation, Metabolic|Biotransformation | |
10331643 Mol. Cell. Biochem. 1999 *Cyclic ADP-Ribose|NAADP|*NADP|ADP ribosyl Cyclase|ADP-ribosyl Cyclase 1|Antigens, CD|Antigens, Differentiation|Adenosine Diphosphate Ribose|NAD+ Nucleosidase|Membrane Glycoproteins|Signal Transduction|N-Glycosyl Hydrolases|Calcium|Kinetics|Catalysis|*Biochemical Phenomena | |
10334322 Diabetes 1999 Humans|Infant|*Point Mutation|Finland|*Sulfonylurea Receptors|*Congenital Hyperinsulinism|Potassium Channels, Inwardly Rectifying|Heterozygote|Islets of Langerhans|Mutation|Homozygote|Insulin Secretion|Pancreatectomy|Exon|Adenosine Triphosphate|Longitudinal Studies | |
10334869 Arch. Biochem. Biophys. 1999 Humans|Animals|Rabbits|Caco-2 Cells|*Membrane Transport Proteins|*Sodium|*Intestine|Biotin|Symporters|cDNA|Membrane Glycoproteins|Pantothenic Acid|Amino Acid Sequence|Xenopus laevis|Biological Transport|Choriocarcinoma|Oocytes|Cloning, Molecular|*Vitamins|Intestine, Small|*Ions | |
10334992 Science 1999 *Bile Acids|Cholesterol 7-alpha-Hydroxylase|bile acid binding proteins|Organic Anion Transporters, Sodium-Dependent|Chenodeoxycholic Acid|Membrane Glycoproteins|Orphan Nuclear Receptors|Hydroxysteroid Dehydrogenases|Ligands|Symporters|Transfection | |
10334993 Science 1999 *Bile Acids|*Ligands|*Orphan Nuclear Receptors|Chenodeoxycholic Acid|NCOA1 protein, human|Steroid Receptor Coactivator 1|Homeostasis|Histone Acetyltransferases | |
10334995 Science 1999 Humans|UDP acetylglucosamine-2-epimerase|*Carbohydrate Epimerases|*Cell Membrane|Sialic Acid|Sialic Acids|Cell Adhesion Molecules|Cell Adhesion|Cell Line|Flow Cytometry|Escherichia coli Proteins | |
10336450 J. Biol. Chem. 1999 Humans|RPA1 protein, human|*Replication Protein A|*Phosphorylation|Renal Dialysis|DNA-Binding Proteins|DNA Replication|CDC2 Protein Kinase|DNA, Single-Stranded|Cell Cycle|Chromatin|CDK2 protein, human|Cyclin-Dependent Kinase 2|Cyclin-Dependent Protein Kinases|Protein Conformation | |
10336645 Eur. J. Biochem. 1999 Male|Animals|Humans|Rats|*Calcium-Independent Phospholipase A2|Phospholipases A2|Base Sequence|RNA Splicing|cDNA|Alternative Splicing|Exons|Amino Acid Sequence|Cytosol|Cloning, Molecular|mRNA|Phospholipases A2, Cytosolic|Isoenzymes|Blotting, Northern|Binding Sites | |
10338214 Cell 1999 Humans|Mice|Animals|*Telomere|Telomeric Repeat Binding Protein 2|Telomeric Repeat Binding Protein 1|DNA|DNA-Binding Proteins|Protein Binding|*Mammals | |
10339564 Proc. Natl. Acad. Sci. U.S.A. 1999 PMC26858 Humans|*Phosphorylation|CDC6 protein, human|*Cell Cycle Proteins|*Cyclin-Dependent Kinases|*DNA Replication|*Nuclear Proteins|S Phase|CDK2 protein, human|Cyclin-Dependent Kinase 2|Cell Cycle|Saccharomyces cerevisiae Proteins|DNA-Binding Proteins|G1 Phase|Cell Nucleus|Budding Yeast|*Cell Cycle Checkpoints | |
10339581 Proc. Natl. Acad. Sci. U.S.A. 1999 PMC26875 Humans|Female|Pregnancy|Hyaluronidase Deficiency|*Hyaluronoglucosaminidase|*Mucopolysaccharidosis|*Multigene Family|Hyaluronan|Amino Acid Sequence|Phenotype|*Mutations|Glycosaminoglycans|Sequence Homology, Amino Acid|Databases, Genetic|*Lysosomes|Hyal2 protein, human|Cell Adhesion Molecules|GPI-Linked Proteins | |
10339590 Proc. Natl. Acad. Sci. U.S.A. 1999 PMC26884 Mice|Animals|oxidized low density lipoprotein|*Macrophages, Peritoneal|*Lipoproteins, LDL|*Macrophage|Apolipoproteins B|Phospholipids|*Lipid Metabolism|Phosphatidyl Choline|Oxidation-Reduction|*Histiocytes|*Protein Processing, Post-Translational|Antibodies, Monoclonal|Apoptosis | |
10339611 Proc. Natl. Acad. Sci. U.S.A. 1999 PMC26905 Humans|*Alzheimer Disease|*Agrin|*Solubility|Senile Plaques|*Brain|Neurofibrillary Tangles|Amyloid beta-Peptides|Heparan Sulfate Proteoglycan|Neurons|Synapses|*Microvasculature | |
10341223 J. Neurosci. 1999 PMC6782594 Animals|*Receptors, N-Methyl-D-Aspartate|*Post-Synaptic Density|*Disks Large Homolog 4 Protein|*Synapses|Guanylate Kinases|Nerve Tissue Proteins|Neurons|Intracellular Signaling Peptides and Proteins|Membrane Proteins|*Brain|Hippocampus|*Signal Transduction|*Mammals|Glutamate|Amino Acid Sequence|*Transcription Factors | |
10343104 Cytogenet. Cell Genet. 1999 Humans|*Fucosyltransferases|In Situ Hybridization, Fluorescence|Base Sequence|Chromosome Mapping|Restriction Mapping|Cloning, Molecular|DNA, Complementary|*Human Chromosome|*Chromosome Structures | |
10347172 J. Biol. Chem. 1999 Animals|*Receptor, Frizzled|*Ligands|*Wnt Signaling Pathway|Wnt Proteins|CTNNB1 protein, human|beta Catenin|Wnt1 Protein|Zebrafish Proteins|Proto-Oncogene Proteins|Xenopus Proteins|Trans-Activators|Xenopus laevis | |
10347183 J. Biol. Chem. 1999 Cricetinae|Animals|Humans|SLC19A1 protein, human|*Reduced Folate Carrier Protein|*Hemagglutinins|CHO Cells|Cricetulus|*Epitopes|Protein Structure, Secondary|Biological Transport|Amino Acid Sequence|Carrier Proteins|Cell Membrane|Methotrexate|Mutagenesis, Site-Directed|Base Sequence|enhanced green fluorescent protein|Green Fluorescent Proteins|Transfection|Folic Acid | |
10347194 J. Biol. Chem. 1999 Humans|Animals|Mice|Rabbits|*Chlorides|potassium-chloride symporters|Symporters|Sodium|Bumethanide|Sodium-Potassium-Chloride Symporters|Potassium|Biological Transport|Cloning, Molecular|Amino Acid Sequence|cDNA|Furosemide|*Cations|Xenopus laevis|*Chlorine|Kidney | |
10347217 J. Biol. Chem. 1999 MDM2 protein, human|*Proto-Oncogene Proteins c-mdm2|*Tumor Suppressor Protein p53|*Ubiquitin|Nuclear Proteins|Ubiquitins|Proto-Oncogene Proteins|Cell Nucleus|Transfections|Mutation | |
10347222 J. Biol. Chem. 1999 Humans|Animals|*Sodium-Bicarbonate Symporters|*Tissue Distribution|Cloning, Molecular|Amino Acid Sequence|Carrier Proteins|Bicarbonates|Xenopus laevis|Chromosome Mapping|Sodium|DNA, Complementary|Membrane Proteins|*Genomics|Introns|Oocytes|RNA, Messenger|Ion Transport|Sequence Homology, Amino Acid|SLC4A7 protein, human | |
10347254 Mol. Pharmacol. 1999 Animals|Rats|Humans|*Receptors, Histamine H3|Histamine|Amino Acid Sequence|G-Protein-Coupled Receptors|cDNA|Brain|Neurotransmitter|Cloning, Molecular|mRNA|Transfection|Sequence Homology, Amino Acid|Neurons|In Situ Hybridization|Forskolin|Tissue Distribution | |
10348910 J. Biochem. 1999 Humans|*Lipoprotein Lipase|*Blood Platelets|2-stearoylglycerol|Glycerides|glyceryl 2-arachidonate|Arachidonic Acids|Endocannabinoids|Phospholipases A2|1,6-bis(cyclohexyloximinocarbonyl)hexane|Cyclohexanones|Phenylmethylsulfonyl Fluoride|Microsomes|Diisopropylfluorophosphate|Stearates | |
10350061 FEBS Lett. 1999 PTPN6 protein, human|*Platelet Endothelial Cell Adhesion Molecule-1|*Phospholipase C gamma1|Protein Tyrosine Phosphatase, Non-Receptor Type 6|PTPN11 protein, human|*Protein Tyrosine Phosphatase, Non-Receptor Type 11|SH2 Domain-Containing Protein Tyrosine Phosphatases|*Protein Binding|src Homology Domains|*Signal Transduction|*Cytoplasm|Phosphorylation|Phosphopeptides|Tyrosine|Proteins|*Cytosol|glycerophosphoinositol glycerophosphodiesterase|*Phosphoric Diester Hydrolases | |
10357856 Microbiol. Mol. Biol. Rev. 1999 PMC98971 *mRNA|*Eukaryotes|*Transcription, Genetic|RNA Polymerase II|Polyadenylation|Poly A|RNA Splicing|RNA Precursor|Polyadenylation Factors|Trans-Acting Factors|Transcription Factors | |
10358005 J. Biol. Chem. 1999 Animals|*mRNA|*Poly(A)-Binding Proteins|Peptide Termination Factors|*Protein Biosynthesis|Peptide Chain Termination, Translational|Saccharomyces cerevisiae Proteins|Poly A|Saccharomyces cerevisiae|*Eukaryotic Cells|Yeast Two-Hybrid System|*Peptides|Protein Binding|GTP Binding Protein | |
10358010 J. Biol. Chem. 1999 Dogs|Animals|*Betaine|Chlorine-36|*Xenopus laevis|*Chlorine|GABA Plasma Membrane Transport Proteins|gamma-Aminobutyric Acid|Sodium|Biological Transport|Oocytes|Cell Membrane|Amino Acid Sequence|Chlorides | |
10358014 J. Biol. Chem. 1999 Humans|Animals|Child|*Proto-Oncogene Proteins c-akt|*Gene Expression Regulation|Phosphorylation|Proto-Oncogene Proteins|IGFBP1 protein, human|Insulin-Like Growth Factor Binding Protein 1|Signal Transduction|Forkhead Box Protein O1|Forkhead Transcription Factors|Transcriptional Activation|Promoter Regions, Genetic|Insulin|Caenorhabditis elegans|Mutation | |
10358045 J. Biol. Chem. 1999 STAT5B protein, human|STAT5 Protein|STAT5A protein, human|*Proto-Oncogene Proteins c-kit|DNA-Binding Proteins|Trans-Activators|Tumor Suppressor Proteins|Phosphorylation|beta-Casein|Transcription, Genetic|Transcriptional Activation|Promoter Regions, Genetic|Stem Cell Factor|Prolactin|DNA|Signal Transduction|Janus Kinase 2|Transfection | |
10358049 J. Biol. Chem. 1999 Animals|Humans|*Sterol Esterase|gastric lipase, human|*Acid Lipase|Protein Conformation|Binding Site|Crystallography, X-Ray|Amino Acid Sequence|Models, Molecular|Active Site|Catalysis|Sequence Homology, Amino Acid|Stomach|Cholesterol Ester Storage Disease | |
10358058 J. Biol. Chem. 1999 Humans|Animals|Chlorocebus aethiops|PLA2G4B protein, human|*Group IV Phospholipases A2|Phospholipases A2|Cytosol|Amino Acid Sequence|COS Cells|Cloning, Molecular|cDNA|Calcium|Genetic Vectors|Enzyme Activation | |
10358072 J. Biol. Chem. 1999 Mice|Animals|Humans|Rats|SLCO1B1 protein, human|*Liver-Specific Organic Anion Transporter, LST-1|Biological Transport|Taurocholate|Thyroid Hormones|estrone sulfate|Estrone|Carrier Proteins|Organic Anion Transporters|Amino Acid Sequence|Liver|estradiol-17 beta-glucuronide|Estradiol|Xenopus laevis|Anion Transport Proteins|RNA, Messenger|Substrate Specificity|Kinetics | |
10358075 J. Biol. Chem. 1999 Humans|Animals|AKT1 protein, human|*Proto-Oncogene Proteins c-akt|*Phosphorylation|Caenorhabditis elegans|PtdIns 3-Kinase|*Gene Expression Regulation|Signal Transduction|Wortmannin|Proto-Oncogene Proteins|IGF1 protein, human|Insulin-Like Growth Factor I|Forkhead Box Protein O1|3-Phosphoinositide-Dependent Protein Kinases|Threonine|Serine|Forkhead Transcription Factors|Insulin | |
10358095 J. Biol. Chem. 1999 Humans|*Transcriptional Activation|*Matrix Metalloproteinase 3|EP300 protein, human|*E1A-Associated p300 Protein|*Promoter Regions, Genetic|Transcription Factors|ets Transcription Factors|DNA-Binding Proteins|Trans-Activators|Nuclear Proteins|Histone Acetyltransferases|Binding Sites|Proto-Oncogene Proteins|Phosphorylation|CREB-Binding Protein|Mitogen-Activated Protein Kinases|Transcription Factor, Ets-1|TYRP1 protein, human | |
10358152 J. Immunol. 1999 Mice|Animals|*src-Family Kinases|Receptors, Antigen, B-Cell|*Antigens, CD19|*B-Lymphocytes|*Signal Transduction|Phosphorylation|Protein-Tyrosine Kinases|Syk Kinase|Enzyme Activation|Phosphatidylinositol 3-Kinases|Intracellular Signaling Peptides and Proteins|Lymphocyte Activation|*Adaptor Proteins, Signal Transducing | |
10358752 Annu. Rev. Immunol. 1999 Humans|IL15 protein, human|*Interleukin-15|Interleukin-15 Receptor|*Lymphocyte Activation|NK Cells|Interleukin-2|IL2RG protein, human|Interleukin Receptor Common gamma Subunit|STAT5A protein, human|STAT5 Transcription Factor|*Cytokines|Signal Transduction|IGBP1 protein, human|Intracellular Signaling Peptides and Proteins|*Cytoplasm|alpha, IL-15R|*Hematopoiesis|Tumor Suppressor Proteins | |
10358769 Annu. Rev. Immunol. 1999 *Phagocytosis|*Macrophages|mannose receptor|Mannose-Binding Lectins|Complement Receptors|Receptors, Cell Surface|Lectins, C-Type|Phagocytes|Receptors, IgG|Mycobacterium tuberculosis|Fc Receptors|Innate Immune Response|Complement | |
10359578 J. Exp. Med. 1999 PMC2193079 Humans|TNFSF13B protein, human|*B-Cell Activating Factor|TNFRSF13C protein, human|Receptor, BAFF|*B Cells|*Tumor Necrosis Factor-alpha|Receptors, Tumor Necrosis Factor|Transmembrane Activator and CAML Interactor Protein|B-Cell Maturation Antigen|Lymphocyte Activation|Germinal Center|T Cells|*Ligands|Cell Differentiation|Immunoglobulins | |
10359595 Mol. Biol. Cell 1999 PMC25369 *Phospholipase A2 Inhibitors|*Golgi Complex|Phospholipases A2|Intracellular Membranes|Endoplasmic Reticulum|Brefeldin A|*Axoneme|Protein Transport|*Membrane|Cytosol|Masoprocol | |
10359825 Proc. Natl. Acad. Sci. U.S.A. 1999 PMC22030 Humans|*Congenital Disorders of Glycosylation|*Saccharomyces cerevisiae|*Mutation|Endoplasmic Reticulum|Glucosyltransferases|Glycosylation|mannosyl(9)-N-acetylglucosamine2|Mannans|ALG6 protein, human|Membrane Proteins | |
10360578 Nature 1999 Humans|WAS protein, human|*Wiskott-Aldrich Syndrome Protein|*Protein Binding|Amino Acid Sequence|Protein Conformation|cdc42 GTP-Binding Protein|Cell Cycle Proteins|GTP-Binding Proteins|Binding Sites|Signal Transduction|rac GTP-Binding Proteins|Models, Molecular | |
10361113 Blood 1999 Mice|Rats|Animals|STAT5B protein, human|STAT5A protein, human|*STAT5 Transcription Factor|*Neutrophils|*Tumor Suppressor Proteins|JAK2 protein, human|Janus Kinase 2|IL3 protein, human|Interleukin-3|Phosphorylation|Trans-Activators|DNA-Binding Proteins|EPO protein, human|Erythropoietin|Activation, Transcriptional|*Myeloid Cell|*Cell Proliferation|*Myeloid Progenitor Cells | |
10362779 Am. J. Physiol. 1999 Animals|Humans|Mice|*Protein Isoforms|Sodium-Bicarbonate Symporters|*Sodium|Amino Acid Sequence|cDNA|Kidney|mRNA|Carrier Proteins|Cloning, Molecular|Tissue Distribution|Blotting, Northern|Kidney Cortex|cDNA Library|Immunoblotting|Brain | |
10364168 J. Biol. Chem. 1999 Humans|lipoteichoic acid|TLR2 protein, human|*Toll-Like Receptor 2|*Lipopolysaccharides|*Peptidoglycan|HEK293 Cells|*Teichoic Acids|Toll-Like Receptor|Toll-Like Receptor 4|NF-kappa B|*Cell Wall|Gram Positive Bacteria|Lipopolysaccharide Receptors|Membrane Glycoproteins|Gram Negative Bacteria|Transductions, Signal|Drosophila Proteins | |
10364181 J. Biol. Chem. 1999 Male|Humans|*Testosterone|*Prolactin|zinc-binding protein|Kinetics|*Prostate Cancer|Prostate|*Biological Transport|Cation Transport Proteins|Zinc|*Testosterone Congeners|PC3 Cells|Glandular Epithelial Cells|Cell Line, Tumor|Aconitate Hydratase|*Biochemical Phenomena|*Protein Transport | |
10364207 J. Biol. Chem. 1999 *Saccharomyces cerevisiae|Saccharomyces cerevisiae Proteins|RNA, Fungal|ATPase|DEAD-box RNA Helicases|Eukaryotic Initiation Factor-4A|TYRP1 protein, human|*Membrane Glycoproteins|Adenosine Triphosphate|RNA|RNA, Messenger|Amino Acid Sequence|Hydrolysis | |
10364220 J. Biol. Chem. 1999 Humans|Mice|Animals|HCRT protein, human|*Orexins|Neuropeptides|melanin-concentrating hormone|Hypothalamic Hormones|Intracellular Signaling Peptides and Proteins|Hypothalamic Area, Lateral|Pituitary Hormones|Protein Precursors|Carrier Proteins|Amino Acid Sequence|Feeding Behavior|cDNA|Cloning, Molecular|Sequence Alignment|mRNA|Gene Expression|Melanins | |
10364222 J. Biol. Chem. 1999 Animals|Chlorocebus aethiops|NT5E protein, human|*5'-Nucleotidase|nucleotidase|*Nucleotidases|*Cytosol|Adenosine Monophosphate|Adenosine|Heart|Myocardium|Inosine Monophosphate|Kinetics|COS-7 Cells|Amino Acid Sequence|Cloning, Molecular|Substrate Specificity|GPI-Linked Proteins | |
10364231 J. Biol. Chem. 1999 Humans|Mice|Animals|*Poly(ADP-ribose) Polymerase Inhibitors|PARP2 protein, human|*Poly ADP Ribose Polymerase|PARP1 protein, human|*Poly (ADP-Ribose) Polymerase-1|*DNA Damage|ADP Ribose, Poly|Base Excision Repair|Amino Acid Sequence|cDNA|Cell Nucleus|*Mammals|Poly ADP Ribosylation | |
10366038 Mech. Ageing Dev. 1999 Humans|Female|Male|Aged|*Duodenum|Enteroendocrine Cells|Cholecystokinin|Somatostatin|*Endocrine Cells|Gastric Inhibitory Polypeptide|Immunohistochemistry|*Aging|Gastrointestinal Tract|Serotonin|Chromogranin A|Immunoenzyme Techniques|Cells, Epithelial|Cell Count|Image Processing, Computer-Assisted | |
10366422 Exp. Cell Res. 1999 Humans|*beta1 Integrin|*Collagen Type VII|FN1 protein, human|Fibronectin|Cell Adhesion|Integrins|Laminin|Fibroblasts|arginyl-glycyl-aspartic acid|Oligopeptides|Binding Site|Skin|Cells, Cultured|Amino Acid Sequence|Antibodies, Monoclonal|Peptide Fragments | |
10366590 J. Cell Biol. 1999 PMC2133156 Animals|*Caenorhabditis elegans|*GLP 1|Caenorhabditis elegans Proteins|TYRP1 protein, human|*Membrane Glycoproteins|Receptors, Notch|*Transcription Factors|Genes, Helminth|Membrane Proteins|Helminth Proteins|Mutations|Allele|Amino Acid Sequence|Signal Transduction|Sequence Homology, Amino Acid|Golgi Apparatus|*Protein Transport|Cloning, Molecular | |
10367886 Cell 1999 *Heat Shock Protein 70|*Mitochondria|*Protein Transport|Saccharomyces cerevisiae Proteins|Mitochondrial Membrane Transport Proteins|Saccharomyces cerevisiae|Carrier Proteins|Membrane Proteins|Membrane Transport Proteins|Intracellular Membranes|Protein Folding|L-Lactate Dehydrogenase (Cytochrome)|Protein Precursors|Biological Transport|Adenosine Triphosphate|*Dyneins|*Kinesin|*Myosins | |
10368288 Structure 1999 Humans|elongation factor Ts|*Peptide Elongation Factor 1|*Escherichia coli|*Guanine Nucleotides|EF Tu|tRNA, Amino Acyl|Guanosine Diphosphate|Guanosine Triphosphate|Protein Conformation|Ribosome|Amino Acid Sequence|Protein Biosynthesis|Models, Molecular|Conserved Sequence | |
10368295 Structure 1999 Humans|*Pulmonary Surfactant-Associated Protein D|Pulmonary Surfactant-Associated Protein A|*alpha-Helices|Amino Acid Sequence|Pulmonary Surfactants|Collectin|Protein Conformation|Ligands|Lung|Models, Molecular|Carbohydrate|Sequence Homology, Amino Acid|Lectins, C-Type|*Protein Domains | |
10369256 Nat. Genet. 1999 Humans|Animals|HHH syndrome|*Hyperammonemia|ornithine transporter|Canada|*Ornithine|*Urea Cycle Disorders, Inborn|Amino Acid Transport Systems, Basic|*Mutations|Amino Acid Metabolism, Inborn Errors|Citrulline|Carrier Proteins|Membrane Transport Proteins|Syndrome|Mitochondrial Proteins|Alleles|Mitochondria | |
10369257 Nat. Genet. 1999 Adult|Humans|Adult-onset citrullinemia type 2|*Citrullinemia|*Protein, Mitochondrial|Argininosuccinate Synthetase|*Mitochondria|Mitochondrial Membrane Transport Proteins|citrin|Calcium-Binding Proteins|Organic Anion Transporters|Mutations|Membrane Transport Proteins|Gene Frequency|Liver|Japan|SLC25A13 protein, human | |
10369264 Nat. Genet. 1999 Humans|Fundus Albipunctatus|*Dark Adaptation|retinol dehydrogenase|*Alcohol Oxidoreductases|Night Blindness|*Mutations|Electroretinography|Retinitis Pigmentosa|DNA Mutational Analysis|*Retinal Dystrophies|Retinal Cone Photoreceptor Cells|Pedigree|11-cis-Retinal|Rhodopsin|Polymerase Chain Reaction | |
10369418 Mol. Immunol. 1999 Mice|Animals|*CD40 Ligand|*Interleukin-4|*Promoter Regions, Genetic|STAT6 protein, human|STAT6 Transcription Factor|NF-kappa B|CD40 Antigens|Immunoglobulin Class Switching|Ig Genes|Trans-Activators|Proto-Oncogene Proteins c-rel|*Immunoglobulin|Transcription, Genetic|Transcription Factors|DNA-Binding Proteins|*Germ Line|Immunoglobulin Constant Regions|Response Elements | |
10369661 EMBO J. 1999 PMC1171401 Humans|Glutathione synthetase deficiency|*Glutathione Synthase|*Amino Acid Metabolism, Inborn Errors|Amino Acid Sequence|Binding Sites|Protein Structure, Secondary|Glutathione|Models, Molecular|Crystallography, X-Ray|gamma-glutamylcysteine|Dipeptides|Sequence Homology, Amino Acid|Adenosine Triphosphate|Kinetics | |
10369662 EMBO J. 1999 PMC1171402 *ADP,ATP Carrier|TOM translocase|*Carrier Proteins|*Mitochondria|Saccharomyces cerevisiae Proteins|Mitochondrial Membrane Transport Proteins|Saccharomyces cerevisiae|*Mitochondrial Membranes|Mitochondrial Proteins|Membrane Transport Proteins|Membrane Proteins|Protein Transport|Protein Precursors|Amino Acid Sequence|Membrane Potential|Adenosine Triphosphate|Adenosine Diphosphate|TIM10 protein, S cerevisiae | |
10369678 EMBO J. 1999 PMC1171418 Animals|*Drosophila|*Fat Body|*Transcription Factors|Drosophila Proteins|DNA-Binding Proteins|Drosophila melanogaster|Nuclear Proteins|Phosphoproteins|Signal Transduction|Toll-Like Receptors|NF-kappa B|Mutations|Antimicrobial Cationic Peptides|Larvae|Membrane Glycoproteins|*Fat Cell|*Anti-Bacterial Agents|Dif protein, Drosophila | |
10369876 Hum. Mol. Genet. 1999 Male|Child|Humans|Female|Child, Preschool|AVP protein, human|*Neurophysins|*Diabetes Insipidus, Neurogenic|*Vasopressin|*Diabetes Insipidus|*Protein Precursors|Arginine Vasopressin|Pedigree|Deprivation, Water|Exon|Mutations|Carrier Proteins|Mutation, Missense|Peptide, Signal|Family|Diabetes Mellitus | |
10371034 FEMS Microbiol. Rev. 1999 Animals|*RNA Precursors|Poly A|Saccharomyces cerevisiae|mRNA|mRNA Cleavage and Polyadenylation Factors|Polyadenylation|3' Untranslated Regions|RNA Polymerase II|Endonucleases | |
10371504 Nat. Med. 1999 intrinsic factor-cobalamin receptor|APOA1 protein, human|*Apolipoprotein A-I|*Intrinsic Factor|Iodine-125|*Iodine Radioisotopes|*Receptors, Cell Surface|*Lipoproteins, HDL|*Endocytosis|Low Density Lipoprotein Receptor-Related Protein-2|*Carrier Proteins|Kidney|Sac, Yolk|Vitamin B 12 | |
10373014 Dev. Dyn. 1999 Animals|Mice|retinoic acid receptor beta|*Retinoic Acid|*Receptors, Retinoic Acid|Hox Gene|Homeodomain Proteins|Transcription Factors|Gene Expression Regulation, Developmental|Rhombencephalon|Carrier Proteins | |
10373362 J. Mol. Biol. 1999 Humans|*Pyrimidine Dimers|DNA Replication|DNA Repair|DNA Damage|DNA, Single-Stranded|Templates, Genetic|Plasmids|Simian virus 40|Base Sequence|Thymine|Single-Stranded DNA-Binding Protein|HeLa Cells|DNA Restriction Enzymes|DNA, Viral|Ultraviolet Rays | |
10373420 J. Biol. Chem. 1999 Humans|Escherichia coli|8-oxodGTPase|*Phosphoric Monoester Hydrolases|8-hydroxy-2'-deoxyguanosine 5'-triphosphate|Deoxyguanine Nucleotides|deoxyadenosine diphosphate|*Deoxyadenine Nucleotides|2'-deoxyadenosine triphosphate|*DNA Repair Enzymes|2-hydroxydeoxyadenosine triphosphate|Adenosine Triphosphate|Pyrophosphatases|Escherichia coli Proteins|Hydrolysis|Substrate Specificity|*Oxidation-Reduction|Kinetics|Mutation | |
10373510 Mol. Cell. Biol. 1999 PMC84259 Animals|Rats|Mice|Humans|RASGRF2 protein, human|ras Guanine Nucleotide Exchange Factors|ras-GRF1|Signal Transduction|Calmodulin|Guanine Nucleotide Exchange Factors|Mitogen-Activated Protein Kinases|Amino Acid Sequence|ras Proteins|*Calcium, Dietary|Ionomycin|*Complement Factor B|Cell Line|Phosphorylation|3'-(1-butylphosphoryl)adenosine|Cultured Cells | |
10373557 Mol. Cell. Biol. 1999 PMC84351 Animals|Humans|DBF4 protein, human|*Cell Cycle Proteins|CDC7 protein, human|Protein-Serine-Threonine Kinases|*Interphase|S Phase|MCM2 protein, human|Minichromosome Maintenance Complex Component 2|DNA Replication|Phosphorylation|Cell Cycle|Cell Division|Nuclear Proteins | |
10373562 Mol. Cell. Biol. 1999 PMC84356 Mice|Animals|*Proteins, Homeo Domain|*Hindbrain|Pre-B-Cell Leukemia Transcription Factor 1|Transcription Factors|Myeloid Ecotropic Viral Integration Site 1 Protein|Proto-Oncogene Proteins|Neoplasm Proteins|DNA|Response Element|Dimerization|Mutation|Pknox1 protein, mouse | |
10374881 Leukemia 1999 *src Homology Domains|platelet protein P47|*Phosphorylation|*Phosphoproteins|*Blood Proteins|JAK2 protein, human|Janus Kinase 2|STAT5A protein, human|STAT5 Transcription Factor|*Adaptor Proteins, Signal Transducing|EPO protein, human|Erythropoietin|Signal Transduction|Erythropoietin Receptor|src-Family Kinases|DNA-Binding Proteins|Proto-Oncogene Proteins c-cbl|Trans-Activators | |
10375506 Development 1999 Animals|*Xenopus laevis|Transcription Factor|TCF Transcription Factors|CTNNB1 protein, human|beta Catenin|Xenopus Proteins|C-terminal binding protein|DNA-Binding Proteins|HMGB Proteins|Transcription Factor 7-Like 1 Protein|Trans-Activators|Transcription Factor 3|Body Patterning|Binding Sites|Lymphoid Enhancer-Binding Factor 1|Gene Expression Regulation, Developmental|Co-Repressors|Embryo, Nonmammalian | |
10375532 Curr. Biol. 1999 CDKN1B protein, human|*Cyclin-Dependent Kinase Inhibitor p27|*Phosphorylation|*S-Phase Kinase-Associated Proteins|Cullin 1|Cullin Proteins|CDC2-CDC28 Kinases|*Ubiquitination|Cyclin-Dependent Kinases|Ubiquitins|Cell Cycle|Cyclin-Dependent Kinase 2|Ubiquitin-Protein Ligases|SKP Cullin F-Box Protein Ligases|Cyclin E|Microtubule-Associated Proteins|Cell Division|Protein Binding | |
10375640 Gene 1999 Animals|Humans|methionine sulfoxide reductase|*Methionine Sulfoxide Reductases|*Fimbriae Proteins|*Transcription Factors|Escherichia coli|*Oxidation-Reduction|Amino Acid Sequence|Bacterial Proteins|Fimbriae, Bacterial|Nucleotide Sequence|Sequence Homology, Amino Acid|Neisseria gonorrhoeae|Streptococcus pneumoniae|Chromosomes | |
10376602 Nature 1999 PMC3637917 Animals|Chlorocebus aethiops|AKT1 protein, human|*Proto-Oncogene Proteins c-akt|*Nitric Oxide|Endothelial Cells|Vascular Endothelial Growth Factor A|NOS3 protein, human|Endothelial Nitric Oxide Synthase|Nitric Oxide Synthase|Phosphorylation|Phosphatidylinositol 3-Kinases|Signal Transduction|COS Cells|Enzyme Activation|Proto-Oncogene Proteins|Serine|Nitric Oxide Synthase Type II|Endothelium, Vascular | |
10376603 Nature 1999 *Phosphorylation|*Proto-Oncogene Proteins c-akt|*Endothelial Cells|*Nitric Oxide Synthase|NOS3 protein, human|Endothelial Nitric Oxide Synthase|Phosphatidylinositol-3-OH Kinase|Nitric Oxide|Enzyme Activation|Proto-Oncogene Proteins|Serine|Endothelium, Vascular|Signal Transduction|Stress, Mechanical|Cells, Cultured | |
10377264 Biochem. J. 1999 PMC1220349 *Proto-Oncogene Proteins c-kit|GRB2 protein, human|*GRB2 Adaptor Protein|GRB7 protein, human|*GRB7 Adaptor Protein|src Homology Domains|Phosphorylation|Signal Transduction|Mitogen-Activated Protein Kinases|Protein Binding|Tyrosine | |
10377387 Proc. Natl. Acad. Sci. U.S.A. 1999 PMC22043 Mice|Animals|JAK2 protein, human|*Janus Kinase 2|*Tyrosine Kinase 2|STAT5B protein, human|Signal Transducer and Activator of Transcription 5B|*Kinases, Janus|*Cytoplasm|src Homology Domain|Phosphorylation|STAT3 protein, human|STAT3 Transcription Factor|Signal Transduction|Growth Hormone|Receptors, Somatotropin|*Cytosol|Carrier Proteins|Adaptor Proteins, Signal Transducing|Trans-Activators | |
10377398 Proc. Natl. Acad. Sci. U.S.A. 1999 PMC22064 Humans|Animals|Mice|*Cholesterol 24-Hydroxylase|*DNA, Complementary|25-hydroxycholesterol|Hydroxycholesterols|24-hydroxycholesterol|Steroid Hydroxylases|Cholesterol|Cytochrome P450|*Brain|*Lipid Metabolism|*Homeostasis|Cloning, Molecular|Cell Line|Transfections | |
10380924 Cell 1999 Animals|*Caenorhabditis elegans|*Protein Kinase|Caenorhabditis elegans Proteins|Protein-Serine-Threonine Kinases|CTNNB1 protein, human|beta Catenin|High Mobility Group Proteins|DNA-Binding Proteins|nmo protein, Drosophila|Mitogen-Activated Protein Kinases|Signal Transduction|Transcription Factors|Phosphorylation|Membrane Proteins|Wnt Proteins|Trans-Activators|Downregulation|Sequence Homology, Amino Acid | |
10380936 Melanoma Res. 1999 *Tumor Suppressor Protein p14ARF|*Homozygote|*Sequence Deletion|*Melanomas|*Loss of Heterozygosity|*Cyclin-Dependent Kinase Inhibitor p16|Skin Neoplasms|Genes, p16|*Mutations|Genes, Tumor Suppressor|Polymorphism, Single-Stranded Conformational|DNA, Neoplasm|Microsatellite Repeats|Polymerase Chain Reaction|Neoplasm Proteins|Chromosome | |
10381005 Neurosci. Lett. 1999 Humans|*Tyrosine 3-Monooxygenase|*Staurosporine|8-chloro-cyclic adenosine monophosphate|*8-Bromo Cyclic Adenosine Monophosphate|Cyclic AMP|mRNA|Transcription, Genetic|Neuroblastoma|Cell Differentiation|Neurons | |
10381560 Biochim. Biophys. Acta 1999 *Hemin|*Kinetics|Lipoproteins, LDL|*Oxidation-Reduction|Lipoproteins, HDL|Atherosclerosis|Antioxidants|Hemopexin|Hydrogen Peroxide|*Plasma | |
10381885 Science 1999 Humans|*Motilin|motilin receptor|Receptors, Gastrointestinal Hormone|Receptors, Neuropeptide|Stomach|Erythromycin|Amino Acid Sequence|Gastrointestinal Motility|Duodenum|*Gastrointestinal Tract|Pyloric Antrum|Protein Binding|Intestine, Small|Colon|Protein Synthesis Inhibitors|Amino Acids | |
10383417 J. Biol. Chem. 1999 *Cytokines|*Signal Transduction|SH3 Domain|JAK2 protein, human|Janus Kinase 2|Phosphoproteins|Adaptor Proteins, Signal Transducing|JAK3 protein, human|Janus Kinase 3|Endosomal Sorting Complexes Required for Transport|Protein Binding|Receptors, Cytokine|Amino Acid Sequence|Phosphorylation|Ubiquitin Thiolesterase|Interleukine 2|Binding Site|Colony-Stimulating Factor, Granulocyte-Macrophage | |
10383923 Drug Metab. Dispos. 1999 Humans|*Skatole|naphthalene|*Naphthalenes|3-methyleneindolenine|Indoles|Cytochrome P450|indole-3-carbinol|indole|Microsomes|Cytochrome P450 Family 2|HPLC|Lung|Biotransformation | |
10385526 J. Cell Biol. 1999 PMC2133159 Humans|*TNF Receptor-Associated Factor 2|TNFAIP3 protein, human|*Tumor Necrosis Factor alpha-Induced Protein 3|*Nuclear Factor-Kappab|*Transcriptional Activation|RIPK1 protein, human|*Receptor-Interacting Protein Serine-Threonine Kinases|CHUK protein, human|IkappaB Kinase|NF-kappa B kinase|Intracellular Signaling Peptides and Proteins|Nuclear Proteins|Tumor Necrosis Factor-alpha|TNF Receptor-Associated Factor 1|DNA-Binding Proteins|*Ubiquitin-Protein Ligases|Signal Transduction|Protein Binding | |
10386589 FEBS Lett. 1999 *Fibrillin|*Matrix Metalloproteinases|FBN2 protein, human|Fibrillin-2|Fibrillin-1|Microfibrils|Extracellular Matrix Proteins|Calcium-Binding Proteins|Microfilament Proteins|Binding Sites|Amino Acid Sequence|Protein Binding|Recombinant Proteins|Exon|Cell Line | |
10389768 Int. J. Cancer 1999 Humans|*Genes, p16|Melanoma, Cutaneous Malignant|Melanoma|Skin Neoplasms|Cyclin-Dependent Kinase Inhibitor p16|CDK6 protein, human|Cyclin-Dependent Kinase 6|Cyclin-Dependent Kinase 4|Mutations|Germ-Line Mutation|Cell Cycle|Polymorphism, Single-Stranded Conformational|*Transfection|Genes, cdc | |
10391218 Nat. Genet. 1999 Humans|Male|Adult|Pregnancy|Female|Mice|Animals|*X-Linked Dominant Chondrodysplasia Punctata|*Mutations|Steroid Isomerases|Genes, Dominant|Heterozygote|Phenotype|Chromosomes, Human, X|Genetic Linkage|Allele|Sterols|Carrier Proteins|Craniofacial Abnormalities | |
10391219 Nat. Genet. 1999 Humans|Male|Female|Adult|*Hydroxysteroids|*Chondrodysplasia Punctata|*Mutations|Steroid Isomerases|Genes, Dominant|DLL3 protein, human|*Membrane Proteins|*Intracellular Signaling Peptides and Proteins|Phenotype|cholesta-5,8-dien-3 beta-ol|Cholestadienols|*Isomerases|Chromosomes, Human, X|Genetic Linkage|Carrier Proteins|Sterols|DNA|Alleles | |
10391221 Nat. Genet. 1999 Humans|Thiamine responsive megaloblastic anemia syndrome|Anemia, Megaloblastic|*Diabetes Mellitus|Thiamin|Hearing Loss, Sensorineural|*Mutations|Carrier Proteins|Membrane Transport Proteins|Deafness|*Anemia, Pernicious|Thiamine Deficiency|SLC19A2 protein, human | |
10391222 Nat. Genet. 1999 Animals|*Vitamin B 1|Anemia, Megaloblastic|*Diabetes Mellitus|Membrane Transport Proteins|Carrier Proteins|Deafness|*Biological Transport|*Anemia|Mutation | |
10391223 Nat. Genet. 1999 Humans|Iran|Anemia, Megaloblastic|*Membrane Transport Proteins|Thiamin|*Mutations|Diabetes Mellitus|Hearing Loss, Sensorineural|Carrier Proteins|Deafness|Exon | |
10391242 Nature 1999 Humans|Amyloid|*Cerebral Amyloid Angiopathy, British Type|Membrane Proteins|Membrane Glycoproteins|Stop Codon|Dementia|Amino Acid Sequence|Mutation|Cerebral Amyloid Angiopathy|Cerebellar Ataxia|Peptide Fragments|Brain|Open Reading Frame|Peptides | |
10391245 Nature 1999 Humans|leukotriene D4 receptor|*Receptors, Leukotriene|Leukotriene D4|Leukotriene C 4|cysteinyl-leukotriene|Leukotrienes|Leukotriene E 4|Leukotriene Antagonists|Muscle, Smooth|Lung|Cysteine|Asthma|Messenger RNA|Membrane Proteins|Sequence Homology, Amino Acid|Calcium | |
10391246 Nature 1999 Animals|*Caenorhabditis elegans|*Wnt Signaling Pathway|*Mitogen-Activated Protein Kinases|NLK protein, human|Protein-Serine-Threonine Kinases|Intracellular Signaling Peptides and Proteins|Caenorhabditis elegans Proteins|*Downregulation|Transcription Factors|Wnt Proteins|DNA-Binding Proteins|Phosphorylation|MAP Kinase Kinase Kinases|Proto-Oncogene Proteins|High Mobility Group Proteins|Zebrafish Proteins|Cytoskeletal Proteins | |
10391247 Nature 1999 Animals|CTNNB1 protein, human|*beta Catenin|*Transcription Factor|Caenorhabditis elegans|*Mitogen-Activated Protein Kinases|NLK protein, human|*Intracellular Signaling Peptides and Proteins|*Protein-Serine-Threonine Kinases|Lymphoid Enhancer Factors|Signal Transduction|Wnt Proteins|MAP Kinase Kinase Kinases|DNA-Binding Proteins|Trans-Activators|Proto-Oncogene Proteins|Zebrafish Proteins|*Gene Expression Regulation|Lymphoid Enhancer-Binding Factor 1 | |
10391915 J. Biol. Chem. 1999 Humans|Animals|SLC3A2 protein, human|*Fusion Regulatory Protein 1, Heavy Chain|*Amino Acids|*Membrane Protein|Transporters, Amino Acid|Antigen 4F2|Carrier Proteins|Amino Acid Sequence|Biological Transport|Xenopus laevis|Oocytes|cDNA|Surface Antigen|Cloning, Molecular|mRNA|*Ion Transport|*Specificity|LAT protein, Human herpesvirus 2 | |
10391953 J. Biol. Chem. 1999 Animals|Humans|*Ultraviolet Rays|HeLa Cells|*DNA|Pyrimidine Dimers|DNA Damage|DNA Repair|Nucleic Acid Conformation|DNA-Binding Proteins|Protein Binding|Fluorescence Resonance Energy Transfer|*Biochemical Phenomena | |
10393175 EMBO J. 1999 PMC1171437 CASP9 protein, human|*Caspase 9|*Cytochromes c|*Hydrolysis|APAF1 protein, human|*Apoptotic Protease-Activating Factor 1|*Caspases|CASP3 protein, human|Procaspase-3|*Apoptosis|2'-deoxyadenosine triphosphate|*Deoxyadenine Nucleotides|Protein Binding|Enzyme Activation|Enzyme Precursors|Adenosine Triphosphate | |
10393322 J. Biochem. 1999 Cricetinae|Animals|Humans|UDP-N-acetylglucosamine transporter|In Situ Hybridization, Fluorescence|*Membrane Transport Proteins|*Golgi Apparatus|UDP-galactose translocator|Monosaccharide Transport Proteins|UDP Galactose|*Cloning, Molecular|Nucleotide Transport Proteins|Uridine Diphosphate N-Acetylglucosamine|Amino Acid Sequence|Biological Transport|Cricetulus|CHO Cells|cDNA|CMP-Sialic Acid | |
10393909 Proc. Natl. Acad. Sci. U.S.A. 1999 PMC22149 *Phospholipase C beta|*C2 Domains|*GTP-Binding Proteins|*Signal Transduction|Type C Phospholipases|Phospholipase C delta|Isoenzymes|Kinetics | |
10393926 Proc. Natl. Acad. Sci. U.S.A. 1999 PMC22166 Humans|*beta Karyopherins|*Cyclin B1|*Active Transport, Cell Nucleus|*ran GTP-Binding Protein|Cell Nucleus|Importin-alpha|Karyopherins|Nuclear Proteins|CDC2 Protein Kinase|Mitosis|G2 Phase|Xenopus Proteins|Cytoplasm|Cytosol | |
10393930 Proc. Natl. Acad. Sci. U.S.A. 1999 PMC22170 Humans|nephrin|*Podocytes|*Membrane Proteins|Kidney Glomerulus|Nephrosis, congenital|Nephrotic Syndrome|*Intercellular Junctions|Proteinuria|Western Blots|*Epithelial Cells|Finland | |
10394364 Mol. Cell 1999 *Clathrin|*Cryoelectron Microscopy|*Crystallography, X-Ray|Coated Pits, Cell-Membrane|Endocytosis|Adaptor Proteins, Vesicular Transport|Models, Molecular|Membrane Proteins | |
10395539 Curr. Biol. 1999 *Cyclin B1|*Active Transport, Cell Nucleus|*Phosphorylation|*Cell Nucleus|*Prophase|*Mitosis|CDC2 Protein Kinase|Cytoplasm|Cell Cycle Proteins|Karyopherins|Protein-Serine-Threonine Kinases|Nuclear Proteins|Interphase|Protein Kinases|Serine|*Translocation, Genetic | |
10395542 Curr. Biol. 1999 Animals|Rats|Mice|*Protein Kinase C|Prospective Studies|FZD1 protein, human|Frizzled Receptors|FZD2 protein, human|AKT1 protein, human|*Protein Kinase B|Wnt Proteins|CTNNB1 protein, human|beta Catenin|Signal Transduction|WNT5A protein, human|Wnt-5a Protein|*G Protein|Xenopus Proteins|Zebrafish Proteins|Trans-Activators|Proto-Oncogene Proteins | |
10395669 J. Immunol. 1999 Humans|Mice|Animals|*IFN-alpha-2|IFNA2 protein, human|*Interferon-alpha|Receptor, Interferon alpha-beta|Receptors, Interferon|Protein Binding|Binding Sites|Interferon Type I|Signal Transduction|Binding, Competitive|Amino Acid Sequence|Transfections|Membrane Proteins|Models, Molecular|Alanine|Antibodies, Monoclonal | |
10395673 J. Immunol. 1999 *Phosphorylation|*Mast Cells|*Interleukin-6|MAPK1 protein, human|Mitogen-Activated Protein Kinase 1|Signal Transduction|Mitogen-Activated Protein Kinases|Calcium-Calmodulin-Dependent Protein Kinases|JNK Mitogen-Activated Protein Kinases|Fc epsilon RI|Enzyme Activation|Cell Cycle Proteins|p38 Mitogen-Activated Protein Kinases|Proto-Oncogene Proteins|Proto-Oncogene Proteins c-vav|Downregulation|Cell Line|MAP Kinase Signaling System | |
10395686 J. Immunol. 1999 Humans|*Peptide, Signal|*Interleukin-16|HIV Infections|*CD4-Positive T-Lymphocytes|*HIV-1|Transfections|Amino Acid Sequence|Golgi Apparatus|Genetic Vectors|Endoplasmic Reticulum|Glycosylation|*HIV Seropositivity | |
10395745 Arch. Biochem. Biophys. 1999 Humans|*Carcinoma, Hepatocellular|alpha-1,6-mannosylglycoprotein beta 1,6-N-acetylglucosaminyltransferase|*Acetylglucosamine|*Liver Neoplasms|N-Acetylglucosaminyltransferases|*Uridine Diphosphate N-Acetylglucosamine|*Cell Line|Glycoprotein|Substrate Specificity|Base Sequence|SDS PAGE|Molecular Weight|Kinetics|Glucosyltransferases|PCR|Mannosides | |
10397721 Blood 1999 Humans|Mice|Animals|*Proto-Oncogene Proteins c-kit|*Megakaryocytes|Stem Cell Factor|*Protein Tyrosine Phosphatase|Phosphorylation|Receptor Protein-Tyrosine Kinases|Signal Transduction|*Upregulation|Phosphotyrosine|Cell Lines|Tyrosine|Amino Acid Sequence|*Transcriptional Activation|Transfections|Protein Processing, Post-Translational|Cell Division|Tumor Cells, Cultured|Cell Differentiation | |
10397761 Mol. Biol. Cell 1999 PMC25438 *beta Karyopherins|*Active Transport, Cell Nucleus|*Sterol Regulatory Element Binding Protein 2|*Leucine Zippers|Helix-Loop-Helix Domain|Nuclear Proteins|*Gene Expression Regulation|Nuclear Localization Signal|Cell Nucleus|Binding Sites|Importin-alpha|CCAAT-Enhancer-Binding Proteins|Amino Acid Sequence|Sterol Regulatory Element Binding Protein 1|*Protein Domains|Sterols | |
10397776 Mol. Biol. Cell 1999 PMC25469 *Crossing Over, Genetic|*Mitochondria|Carrier Proteins|Saccharomyces cerevisiae Proteins|Mitochondrial Membrane Transport Proteins|Intracellular Membranes|Saccharomyces cerevisiae|Membrane Transport Proteins|Membrane Proteins|Biological Transport|Amino Acid Sequence|Protein Precursors|ARHGEF5 protein, human|*Rho Guanine Nucleotide Exchange Factors|HSP70 Heat-Shock Proteins|Repressor Proteins|HAVCR1 protein, human|*Hepatitis A Virus Cellular Receptor 1 | |
10398604 Science 1999 Humans|Mice|Animals|TNFSF13B protein, human|*B-Cell Activating Factor|TNF protein, human|*Tumor Necrosis Factor-alpha|B-Cell Activation Factor Receptor|Receptors, Tumor Necrosis Factor|B Cells|Monocytes|Immunoglobulin|Recombinant Proteins|Cytokines|Interferon-gamma|Spleen|Lymphocyte Activation|Antibody Formation | |
10399920 Cell 1999 *Growth Cones|netrin-2|*Netrin|Receptors, Netrin|DCC protein, human|Deleted in Colorectal Carcinoma Protein|NTN1 protein, human|Netrin 1|*Ligands|Axons|Receptors, Cell Surface|Nerve Growth Factors|*Carrier Proteins|Caenorhabditis elegans Proteins|Tumor Suppressor Proteins|Membrane Proteins|Cell Membrane|Signal Transduction | |
10400613 J. Biol. Chem. 1999 Animals|Chlorocebus aethiops|Humans|CD39 antigen|*Apyrase|*Diphosphates|*Hydrolysis|*Antigens, CD|Adenosine Triphosphatases|Adenosine Diphosphate|Adenosine Triphosphate|COS-7 Cells|Transfections|Recombinant Proteins|Substrate Specificity|Amino Acid Sequence|*Biochemical Phenomena|Magnesium | |
10400691 J. Biol. Chem. 1999 Mice|Animals|Scd2 protein, mouse|*Stearoyl-CoA Desaturase|Nuclear Proteins|Promoter Regions, Genetic|CCAAT-Enhancer-Binding Proteins|SREBP 1c|Transcription, Genetic|Binding Sites|Activation, Transcriptional|*Sterols|Genes, Reporter|mRNA|Gene Expression Regulation, Enzymologic|Cell Differentiation|Adipocytes|Cell Nucleus | |
10400704 J. Biol. Chem. 1999 Humans|*Phosphorylation|*Respiratory Burst|*Granulocyte-Macrophage Colony-Stimulating Factor|*Neutrophils|*Macrophage Colony-Stimulating Factor|4-ethoxymethylene-2-phenyl-2-oxazoline-5-one|Formylmethionylleucylphenylalanine|NADPH Oxidase|Superoxide|neutrophil cytosol factor 67K|Phosphoproteins|Enzyme Activation|Phorbol Myristate Acetate|bisindolylmaleimide I|Maleimides|Protein Kinase C|Protein Tyrosine Kinase|Indoles | |
10401004 Hum. Mol. Genet. 1999 Humans|*Menkes Kinky Hair Syndrome|*Copper|Copper-Transporting ATPases|ATPase|Cation Transport Proteins|*Protein Transport|Biological Transport|Mutation|Amino Acid Sequence|Plasma Membrane|Cell Line|Blotting, Western|Phenotype|Fibroblasts | |
10405317 Biochem. Biophys. Res. Commun. 1999 Male|Chlorocebus aethiops|Pregnancy|Female|Animals|Humans|Rats|Cattle|*Neuraminidase|In Situ Hybridization, Fluorescence|*Chromosome Mapping|cDNA|Blotting, Northern|*Gangliosides|Base Sequence|Cloning, Molecular|Amino Acid Sequence|Polymerase Chain Reaction|DNA Primers|cDNA Library|COS-1 Cells|RNA, Messenger|Cytosol|Sequence Homology, Amino Acid|Open Reading Frame|Sequence Analysis, DNA | |
10405341 Biochem. Biophys. Res. Commun. 1999 Male|Humans|*Seminal Vesicles|arachidonate epoxygenase|*Cytochrome P450|cytochrome P-450 CYP4B1|Aryl Hydrocarbon Hydroxylases|*Gene Expression|Amino Acid Sequence|cDNA|Cloning, Molecular|Base Sequence|Hydroxylation|CYP3A5|Blotting, Northern | |
10406467 Mol. Endocrinol. 1999 Humans|*Steroid 17-alpha-Hydroxylase|17-alpha-Hydroxypregnenolone|*Models, Molecular|Substrate Specificity|Binding Site|*Mutations|17-alpha-Hydroxyprogesterone|Mutagenesis, Site-Directed|Amino Acid Sequence|Redox|Steroids|Progesterone|*Lyases | |
10406800 EMBO J. 1999 PMC1171471 Humans|Mice|Guinea Pigs|Rats|Animals|*Listeria monocytogenes|*Host Specificity|Listeriosis|CDH1 protein, human|*E-Cadherins|*Antigens, CD|Bacterial Protein|Membrane Proteins|Amino Acid Sequence|Signal Transduction|*Amino Acids|Disease Models, Animal | |
10409506 Development 1999 Animals|*Hedgehog Proteins|*Signal Transduction|Drosophila Proteins|Transcription Factor|Drosophila|Gene Expression Regulation, Developmental|Drosophila melanogaster|Cyclic AMP-Dependent Protein Kinases|DNA-Binding Proteins|Morphogenesis|Transcription, Genetic|Protein Processing, Post-Translational|Phosphorylation|Cell Nucleus|Embryo, Nonmammalian | |
10409623 J. Biol. Chem. 1999 Humans|Cricetinae|Animals|CHO Cells|Cricetulus|CD71 antigen|*Transferrin Receptor|TFR2 protein, human|Transferrin|Iron|*Antigens, CD|Liver|Amino Acid Sequence|*Cloning, Molecular|Cell Membrane|RNA, Messenger|Membrane Protein|Transfections|Base Sequence | |
10409679 J. Biol. Chem. 1999 Animals|Chlorocebus aethiops|Humans|*DNA, Complementary|Amino Acid Sequence|Cloning, Molecular|Base Sequence|Carbonic Anhydrase|Transfections|Sequence Alignment|Gene Expression|Recombinant Proteins|Chromosome Mapping|*X Chromosome|Isozymes|Sequence Homology, Amino Acid|COS-7 Cells|Blotting, Northern|Mitochondria|RNA, Messenger|Cytosol | |
10409696 J. Biol. Chem. 1999 Animals|*Drosophila|*Rel-Related Protein|Rel protein, Drosophila|Drosophila Proteins|NF-kappa B|DNA-Binding Proteins|Oncogene Proteins v-rel|RELA protein, human|Transcription Factor RelA|attacin antibacterial protein, insect|Gene Expression Regulation|Promoter Regions, Genetic|Signal Transduction|*Gene Expression|DNA | |
10409699 J. Biol. Chem. 1999 Female|Pregnancy|Rats|Animals|Humans|mannosyl-oligosaccharide 1,2-alpha-mannosidase|*DNA, Complementary|*Mannose|*Mannosidases|*Endoplasmic Reticulum|*Oligosaccharides|Golgi Apparatus|Cloning, Molecular|Base Sequence|Amino Acid Sequence|Substrate Specificity|Recombinant Proteins|*Mammals|Transfection|Polymerase Chain Reaction|*Carbohydrate Metabolism|Open Reading Frame|Isomerism | |
10409723 Mol. Cell. Biol. 1999 PMC84375 Animals|*Drosophila|Drosophila Proteins|Period Circadian Proteins|ARNTL Transcription Factors|CLOCK Proteins|Drosophila melanogaster|Trans-Activators|Transcription, Genetic|Nuclear Proteins|Circadian Rhythm|Helix-Loop-Helix Motifs|*Homeostasis|*Dimerization|timeless protein, Drosophila | |
10409742 Mol. Cell. Biol. 1999 PMC84397 Humans|Mice|Animals|KSR-1 protein kinase|Caenorhabditis elegans|Drosophila melanogaster|Protein Kinases|*Signal Transduction|Protein-Tyrosine Kinases|Mitogen-Activated Protein Kinases|Calcium-Calmodulin-Dependent Protein Kinases|ras Proteins|Proto-Oncogene Proteins c-raf|MAP Kinase Kinase 1|Proto-Oncogene Proteins|Phosphorylation|geldanamycin|Lactams, Macrocyclic|Benzoquinones|3T3 Cells|HSP90 Heat-Shock Proteins | |
10409767 Mol. Cell. Biol. 1999 PMC84430 *Receptors, Aryl Hydrocarbon|ARNT protein, human|*Aryl Hydrocarbon Receptor Nuclear Translocator|*Ligands|Helix-Loop-Helix Motifs|Basic Helix-Loop-Helix Transcription Factors|Protein Binding|Gene Expression Regulation|Dioxins|HSP90 Heat-Shock Proteins|Activation, Transcriptional|Cell Line|*Cell Nucleus|Nuclear Proteins | |
10411507 Science 1999 Humans|Animals|Mice|*Chromatids|pituitary tumor-transforming protein 1, human|Securin|Anaphase Promoting Complex|Cell Cycle Proteins|Anaphase|Separase|Saccharomyces cerevisiae Proteins|Saccharomyces cerevisiae|Nuclear Proteins|Chromosomal Proteins, Non-Histone|Ubiquitin-Protein Ligases|Cell Cycle|Metaphase|Phosphoproteins|Mitosis|*Tumorigenesis|*Vertebrate | |
10411887 Proc. Natl. Acad. Sci. U.S.A. 1999 PMC17528 Humans|involucrin|transglutaminase 1|*Esters|*Protein Precursors|*Transglutaminases|Epidermis|Keratinocytes|Cell Membrane|Amino Acid Sequence|Ceramides|Substrate Specificity|Glutamine|Peptide Fragments|Putrescine | |
10411933 Proc. Natl. Acad. Sci. U.S.A. 1999 PMC17574 Animals|Humans|Rabbits|MFGE8 protein, human|*Antigens, Surface|*Milk Proteins|*Amyloid|*Amyloidosis|*Amyloidogenic Proteins|milk fat globule|Glycoprotein|*Aorta|*Smooth Muscle Cell|Amino Acid Sequence|Peptides|Electron Microscopy|Glycolipids | |
10412986 Cell 1999 *Organelle Biogenesis|mitochondrial transcription factor A|DNA-Binding Proteins|Mitochondrial Proteins|Nuclear Respiratory Factors|NF-E2-Related Factor 1|Trans-Activators|GA-Binding Protein Transcription Factor|Nuclear Proteins|Nuclear Respiratory Factor 1|*Thermogenesis|Mitochondria|Promoter Regions, Genetic|Muscle, Skeletal|Gene Expression | |
10413516 Biochemistry 1999 Humans|*Epitopes|recombinant soluble CD4|CD4 Molecule|*HIV Envelope Protein gp120|*Binding Site|Receptors, CCR5|HIV-1|Immunoglobulin Fab Fragments|Protein Binding|Neutralization Tests|Amino Acid Sequence|Antibodies, Monoclonal|Cell Line|CCR5 protein, human | |
10415025 J. Immunol. 1999 Humans|*Extracellular Signal Regulated Kinases|*Protein Tyrosine Phosphatase|MAPK1 protein, human|Mitogen-Activated Protein Kinase 1|MAPK3 protein, human|Mitogen-Activated Protein Kinase 3|PTPN7 protein, human|Protein Tyrosine Phosphatases, Non-Receptor|Phosphorylation|Signal Transduction|Calcium-Calmodulin-Dependent Protein Kinases|Intracellular Signaling Peptides and Proteins|Protein-Tyrosine Kinases|MAP Kinase Signaling System|Protein Binding|Receptor-Like Protein Tyrosine Phosphatases, Class 7|MAP Kinase Kinase 1|Nerve Tissue Proteins | |
10415057 J. Immunol. 1999 Mice|Animals|*Lipopolysaccharides|*Macrophage|CCL4 protein, human|Macrophage Inflammatory Protein 1-beta|CXCL2 protein, human|Macrophage Inflammatory Protein 2|IL10 protein, human|IL10|CCL3 protein, human|Macrophage Inflammatory Protein 1-alpha|Chemokine CXCL10|Interferon-gamma|CCL2 protein, human|Monocyte Chemoattractant Protein-1|mRNA|STAT1 protein, human|STAT1 Transcription Factor|Macrophages, Peritoneal | |
10415121 Arch. Biochem. Biophys. 1999 Humans|Guinea Pigs|Animals|alkylglycerone-phosphate synthase|*Alkyl and Aryl Transferases|Peroxisomes|Amino Acid Sequence|Microbodies|Phospholipids, Ether | |
10415122 Arch. Biochem. Biophys. 1999 *Receptor, Interleukin-12|*STAT4 Transcription Factor|DNA-Binding Proteins|Signal Transduction|Trans-Activators|Phosphorylation|Sequences, Amino Acid|Interleukin 12|SH2 Domain|Phosphotyrosine|Binding Sites|Tyrosine|Mutagenesis, Site-Directed|Phosphopeptides | |
10417378 Science 1999 Animals|*Cryptochromes|Period Circadian Proteins|Photoreceptor Cells, Invertebrate|Drosophila Proteins|Drosophila|Drosophila melanogaster|Biological Clocks|Eye Proteins|Circadian Rhythm|Nuclear Proteins|Cell Nucleus|Gene Expression Regulation|Darkness|Receptors, G-Protein-Coupled|timeless protein, Drosophila | |
10419465 J. Biol. Chem. 1999 Chlorocebus aethiops|Mice|Animals|*Saccharomyces cerevisiae|*Phosphoinositides|*Insulin|phosphatidylinositol 5-phosphate|Phosphatidylinositol Phosphates|*Insulin, Regular, Human|Saccharomyces cerevisiae Proteins|*Yeast, Dried|PI-3 Kinase|3T3-L1|Phosphorylation|Substrate Specificity|Phosphotransferases (Alcohol Group Acceptor)|Adipocytes|COS Cells|Wortmannin|Sequence Homology, Amino Acid|Amino Acid Sequence | |
10419486 J. Biol. Chem. 1999 Animals|Humans|diphosphoinositol polyphosphate phosphohydrolase|diadenosine 5',5''''-P1,P6-hexaphosphate|*Schizosaccharomyces|*Saccharomyces cerevisiae|*Substrate Specificity|*Hydrolases|*Acid Anhydride Hydrolases|*Dinucleoside Phosphates|Phosphoric Monoester Hydrolases|Pyrophosphatases|Inositol Phosphates|Amino Acid Sequence|Escherichia coli Proteins|Sequence Homology, Amino Acid|Hydrolysis|Bacterial Proteins|Kinetics | |
10419495 J. Biol. Chem. 1999 Humans|Mice|Animals|*Peroxisomes|Eci2 protein, mouse|*Isomerase, Enoyl-CoA|Carbon-Carbon Double Bond Isomerases|Microbodies|Saccharomyces cerevisiae|Amino Acid Sequence|octenoyl-coenzyme A|Acyl Coenzyme A|*Mammals|Cloning, Molecular|Isomerism | |
10421367 Nature 1999 Rats|Cricetinae|Animals|Mice|Humans|melanin-concentrating hormone|HEK293 Cells|*Hypothalamic Hormones|*Pituitary Hormones|*Melanins|melanin-concentrating hormone receptor|Receptors, Pituitary Hormone|*Ligands|GPR1 protein, human|Receptors, G-Protein-Coupled|Receptors, Somatostatin|Cyclic AMP|Amino Acid Sequence|Forskolin|Signal Transduction|Hypothalamus|Messenger RNA|CHO Cells | |
10421368 Nature 1999 Animals|Cricetinae|melanin-concentrating hormone receptor|melanin-concentrating hormone|*Melanins|Hypothalamic Hormones|Pituitary Hormones|*Receptors, Pituitary Hormone|Receptors, Somatostatin|GPRC5C protein, human|G-Protein-Coupled Receptors|Cyclic AMP|Signal Transduction|Ligands|Amino Acid Sequence|CHO Cells|Calcium | |
10421574 Curr. Biol. 1999 *Phosphorylation|Protein Kinase C beta|3-Phosphoinositide-Dependent Protein Kinases|Protein Binding|Amino Acid Sequence|*Hydrophobic and Hydrophilic Interactions|Serine|Binding Sites | |
10421629 Genes Dev. 1999 PMC316878 CTNNB1 protein, human|*beta Catenin|*Axin Protein|Glycogen Synthase Kinase 3 beta|Wnt Proteins|Trans-Activators|Signal Transduction|Repressor Proteins|Phosphorylation|Protein Binding|Calcium-Calmodulin-Dependent Protein Kinases|Zebrafish Proteins|Adenomatous Polyposis Coli Protein|Carrier Proteins|Proto-Oncogene Proteins|Amino Acid Sequence|Xenopus Proteins|Adaptor Proteins, Signal Transducing | |
10421633 Genes Dev. 1999 PMC316888 *Promoter Regions, Genetic|Transcription Factors|POU2F1 protein, human|*Octamer Transcription Factor-1|RNA Polymerase II|Transcription, Genetic|DNA-Binding Proteins|RNA Polymerase III|Binding Sites|TATA Box|TATA-Box Binding Protein|RNA, Small Nuclear|POU2AF1 protein, human|Trans-Activators|Regulatory Sequences, Nucleic Acid|Host Cell Factor C1|Protein Binding|DNA | |
10421658 Hepatology 1999 Humans|Rats|Animals|P-glycoprotein 2|*Bilirubin|Abcc2 protein, rat|*ATP-Binding Cassette Transporters|ATP Binding Cassette Transporter, Subfamily B|multidrug resistance-associated protein 2|Multidrug Resistance-Associated Proteins|Biological Transport|Adenosine Triphosphate|Liver|Active Transport|Hepatocytes|Anion Transport Proteins|Bile|Leukotriene C 4 | |
10421843 Genes Cells 1999 *src Homology Domains|*Tyrosine|*Suppressor of Cytokine Signaling Proteins|JAK2 protein, human|Janus Kinase 2|*Janus Kinases|Signal Transduction|DNA-Binding Proteins|Repressor Proteins|Trans-Activators|Intracellular Signaling Peptides and Proteins|Suppressor of Cytokine Signaling 1 Protein|Phosphorylation|Suppressor of Cytokine Signaling 3 Protein|STAT3 Transcription Factor|Cytokines|Amino Acid Sequence | |
10424882 J. Histochem. Cytochem. 1999 Animals|Rats|Humans|*Neuroendocrine Cells|HEK293 Cells|*Isoforms|*Cerebellum|Calcium Channels, R-Type|Calcium Channels|Insulinoma|Neurons|Purkinje Cells|Amino Acid Sequence|Transfections|Membrane Proteins|Cation Transport Proteins|Brain|Immunoblotting|Pancreatic Neoplasms | |
10424889 J. Histochem. Cytochem. 1999 Cattle|Humans|Animals|*Microfibril|microfibrillar protein|Contractile Proteins|Extracellular Matrix Proteins|Tropoelastin|Elastin|Fibrillins|Elastic Fibers|Microfilament Proteins|Microscopy, Immunoelectron | |
10425179 Biochem. Biophys. Res. Commun. 1999 *Platelet Endothelial Cell Adhesion Molecule-1|*Glycosylation|Endothelial Cells|Antigens, Differentiation, Myelomonocytic|CDH1 protein, human|Antigens, CD|Cell Line|Cell Membranes|Cells, Cultured|Interactions, Cell|Dimerization|E Cadherin | |
10425206 Biochem. Biophys. Res. Commun. 1999 Humans|*Monocytes|*PPAR gamma|Thiazolidinediones|FABP4 protein, human|*Fatty Acid-Binding Proteins|Transcription Factors|Troglitazone|Rosiglitazone|mRNA|Chromans|Fatty Acid-Binding Protein 7|Cell Differentiation|Neoplasm Proteins|Hypoglycemic Agents|Adipocytes|Thiazoles|Macrophages|Gene Expression | |
10425211 Biochem. Biophys. Res. Commun. 1999 Humans|Systemic carnitine deficiency|SLC22A5 protein, human|Solute Carrier Family 22 Member 5|*Carnitine|*Cardiomyopathy|*Hyperammonemia|*Muscular Diseases|*Mutation|DNA Mutational Analysis|Organic Cation Transport Proteins|*RNA Splicing|Missense Mutation|Membrane Proteins|Exon|Intron|Mutation, Nonsense | |
10426996 Science 1999 Humans|TLR2 protein, human|*Toll-Like Receptor 2|*Lipoproteins|Nuclear Factor-Kappab|Toll-Like Receptors|Toll-Like Receptor 4|Monocytes|Lipopolysaccharides|*Apoptosis|Membrane Glycoproteins|Signal Transduction|Lipopolysaccharide Receptors|Cell Line|Drosophila Proteins|Transfections | |
10427092 J. Cell Biol. 1999 PMC2156182 *Focal Adhesion Kinase|PTK2 protein, human|*Focal Adhesion Kinase 1|p130 Crk-Associated Substrate|PTEN protein, human|*PTEN Phosphohydrolase|Mitogen-Activated Protein Kinases|*Cell Motility|Integrins|Paxillin|Phosphorylation|Signal Transduction|Mitogen-Activated Protein Kinase Kinases|Calcium-Calmodulin-Dependent Protein Kinases|Cell Adhesion Molecules|src Homology Domains|Cell Adhesion|Retinoblastoma-Like Protein p130 | |
10428031 Cell 1999 Mice|Animals|*Circadian Clocks|Cryptochrome|Period Circadian Proteins|Nuclear Proteins|Suprachiasmatic Nucleus|ARNTL Transcription Factors|CLOCK Proteins|Photoreceptor Cells, Invertebrate|Eye Proteins|Circadian Rhythm|Drosophila Proteins|Cell Cycle Proteins|Trans-Activators|Gene Expression Regulation|Cell Nucleus|RNA, Messenger|Receptors, G-Protein-Coupled|*Feedback | |
10428864 J. Biol. Chem. 1999 Cricetinae|Animals|Humans|membrane-bound transcription factor peptidase, site 1|*Sterol Regulatory Element Binding Proteins|HEK293 Cells|*Proprotein Convertases|protease C|*Serine Endopeptidases|SREBP cleavage-activating protein|Intracellular Signaling Peptides and Proteins|Membrane Proteins|Nuclear Proteins|CCAAT-Enhancer-Binding Proteins|Sterol Regulatory Element Binding Protein 2|Endoplasmic Reticulum|Sterol Regulatory Element Binding Protein 1|Golgi Apparatus|Protein Processing, Post-Translational|Amino Acid Sequence|Cholesterol | |
10428961 EMBO J. 1999 PMC1171499 Animals|*Axin Protein|*Glycogen Synthase Kinase 3 beta|LEF1 protein, human|*Lymphoid Enhancer-Binding Factor 1|CTNNB1 protein, human|beta Catenin|Wnt Proteins|Dishevelled Proteins|Signal Transduction|Wnt1 Protein|Adaptor Proteins, Signal Transducing|Trans-Activators|Repressor Proteins|Calcium-Calmodulin-Dependent Protein Kinases|Phosphoproteins|Transcription Factors|DNA-Binding Proteins|Glycogen Synthase Kinases | |
10430017 Eur. J. Cell Biol. 1999 Animals|Humans|*Peroxin|Peroxisomes|Membrane Protein|Saccharomyces cerevisiae|Intracellular Membranes|Saccharomyces cerevisiae Proteins|Microbodies|Amino Acid Sequence|Green Fluorescent Proteins|ATP-Binding Cassette Transporters|Sequence Homology, Amino Acid|Pex3 protein, human|Lipoproteins|PEX3 protein, S cerevisiae | |
10430867 Proc. Natl. Acad. Sci. U.S.A. 1999 PMC17704 Animals|Humans|ADA protein, human|*Adenosine Deaminase|*RNA Precursors|Drosophila melanogaster|RNA Editing|*tRNA|Inosine|Amino Acid Sequence|tRNA(Ala)|Double-Stranded RNA|Base Sequence|RNA-Binding Proteins|Substrate Specificity|Adenosine|cDNA|Cloning, Molecular|ADAR1 protein, human|Adar protein, Drosophila | |
10430883 Proc. Natl. Acad. Sci. U.S.A. 1999 PMC17720 Humans|*Mucin|UDP-N-acetylglucosamine-peptide beta-N-acetylglucosaminyltransferase|*N-Acetylglucosaminyltransferases|*Gastric Mucosa|MUC1 protein, human|*Mucin-1|*Cloning, Molecular|*Glycans|Stomach Neoplasms|Metaplasia|Amino Acid Sequence|cDNA|Transfection|Adenocarcinoma|UN1 sialoglycoprotein, human|Leukosialin | |
10431236 Nat. Genet. 1999 *Tangier Disease|ABCA1 protein, human|*ATP Binding Cassette Transporter 1|Familial HDL deficiency|*Hypoalphalipoproteinemias|Hypolipoproteinemias|*Mutations|ATP-Binding Cassette Transporters|High Density Lipoprotein Cholesterol|Pedigree|Glycoproteins | |
10431835 FEBS Lett. 1999 Rats|Humans|Animals|N-acylmannosamine kinase|Phosphotransferases (Alcohol Group Acceptor)|UDP-glucosamine|*Glucosamine|Carbohydrate Epimerases|N-Acetylneuraminic Acid|uridine diphosphate kinase|*Nucleoside-Diphosphate Kinase|Base Sequence|*Racemases and Epimerases|Escherichia coli Proteins|*Neuraminic Acids|Amino Acid Sequence|cDNA|Cell Lines|Catalysis | |
10432220 Mol. Cell. Endocrinol. 1999 Female|Pregnancy|Rats|Animals|IL1A protein, human|*Interleukin-1alpha|*Serotonin|*Transcription Factor AP-1|*Promoter Regions, Genetic|Base Sequence|*Cloning|Transcription, Genetic|Interleukin 1|TATA Box|*Smooth Muscle Cells|mRNA|*Uterus|Myometrium|Cloning, Molecular | |
10432293 Biochem. J. 1999 PMC1220429 *Phosphotyrosine|*PtdIns|SH2 Domain|Adaptor Proteins, Signal Transducing|Phosphorylation|Blood Proteins|Carrier Proteins|Binding Sites|Amino Acid Sequence|Sequence Homology, Amino Acid|Cell Line | |
10433268 Neuron 1999 Animals|Rats|*Disks Large Homolog 4 Protein|postsynaptic density proteins|*Receptors, N-Methyl-D-Aspartate|CTTN protein, human|*Cortactin|*Nerve Tissue Proteins|SAP90-PSD95 Associated Proteins|Intracellular Signaling Peptides and Proteins|Neurons|Membrane Proteins|Synapses|Guanylate Kinases|Adaptor Proteins, Signal Transducing|*Cell Membrane|*Signal Transduction|Protein Transport|Protein Binding|Hippocampus | |
10433269 Neuron 1999 postsynaptic density proteins|*Nerve Tissue Proteins|*Disks Large Homolog 4 Protein|Proteins, Homer|metabotropic glutamate receptor type 1|Neurons|NMDA Receptors|Synapses|Intracellular Signaling Peptides and Proteins|Neuropeptides|Membrane Proteins|GRM5 protein, human|Receptor, Metabotropic Glutamate 5|Adaptor Proteins, Signal Transducing|Hippocampus|Signal Transduction | |
10433356 J. Interferon Cytokine Res. 1999 IL10 protein, human|*Interleukin-10|*Signal Transduction Pathway|STAT3 protein, human|Signal Transducer and Activator of Transcription 3|Receptor, Interleukin-10|Phosphorylation|*Gene Expression|Suppressor of Cytokine Signaling Proteins|SOCS3 protein, human|Suppressor of Cytokine Signaling 3 Protein|TYK2 Kinase|DNA-Binding Proteins|Trans-Activators|Gene Expression Regulation|Monocytes|Tumor Necrosis Factor-alpha|Cytokines | |
10433824 Dev. Biol. 1999 PMC4530617 Chick Embryo|Animals|Mice|*Drosophila|GLI1 protein, human|*Zinc Finger Protein GLI1|Drosophila melanogaster|Chicken|Hedgehog Proteins|Transcription Factors|Trans-Activators|Drosophila Proteins|Repressor Proteins|Zinc Finger Protein Gli3|Oncogene Proteins|Kruppel-Like Transcription Factors|Xenopus Proteins|Nerve Tissue Proteins|Gene Expression Regulation, Developmental|Serine Threonine Kinase|Amino Acid Sequence | |
10434065 Biochim. Biophys. Acta 1999 Animals|Cattle|Humans|*Ligases, Co A|*Mitochondria, Liver|*Carboxylic Acids|Kinetics|*Xenobiotics|*Acids, Fatty|Ligases|Substrate Specificity|Benzoic Acid|*Catalysis|Benzoate|Cations | |
10435585 Oncogene 1999 Humans|Rats|Animals|CHEK2 protein, human|Checkpoint Kinase 2|Cell Cycle Proteins|CHEK1 protein, human|Checkpoint Kinase 1|Cell Cycle|Phosphorylation|Ataxia Telangiectasia Mutated Proteins|Tumor Suppressor Proteins|Ataxia-Telangiectasia|DNA Damage|DNA-Binding Proteins|Protein Kinases|DNA Replication|Schizosaccharomyces pombe|G2 Phase|Cell Division|Signal Transduction | |
10435622 Oncogene 1999 Humans|*Ataxia Telangiectasia|*Phosphorylation|*Tumor Suppressor Protein p53|ATR protein, human|*Ataxia Telangiectasia Mutated Proteins|Protein Kinase, DNA-Activated|Cell Cycle Proteins|*DNA|Tumor Suppressor Proteins|DNA-Binding Proteins|Nuclear Proteins|DNA Damage|Serine|Signal Transduction|Phosphatidylinositol 3-Kinases|HeLa Cells | |
10436018 Mol. Biol. Cell 1999 PMC25495 Humans|ORC1 protein, human|Origin Recognition Complex|*DNA Replication|CDC6 protein, human|Cell Cycle Proteins|Nuclear Proteins|*Binding Site|Saccharomyces cerevisiae Proteins|Cell Cycle|Saccharomyces cerevisiae|Protein Binding|*Nucleotides|Adenosine Triphosphate|CDC6 protein, S cerevisiae | |
10436022 Mol. Biol. Cell 1999 PMC25500 *Clathrin|*Coated Pits, Cell-Membrane|clathrin assembly protein AP180|Monomeric Clathrin Assembly Proteins|Endocytosis|Adaptor Protein Complex 2|Adaptor Proteins, Vesicular Transport|Clathrin Adaptor Protein Complex 1|trans Golgi Network|Golgi Apparatus|Nerve Tissue Proteins|Plasma Membrane|Membrane Proteins|Phosphoproteins|Protein Binding|Green Fluorescent Proteins|Transferrin|Receptor, Mannose 6 Phosphate | |
10436028 Mol. Biol. Cell 1999 PMC25515 Adaptor Proteins, Vesicular Transport|Clathrin|Phosphoproteins|Adaptor Protein Complex 2|*Adaptor Proteins, Signal Transducing|Adaptor Protein Complex 1|Nerve Tissue Proteins|Monomeric Clathrin Assembly Proteins|Saccharomyces cerevisiae|Membrane Proteins|Amino Acid Sequence|Coated Vesicles|Cloning, Molecular | |
10438503 J. Biol. Chem. 1999 Cricetinae|Animals|Humans|*Sterol O-Acyltransferase|*CoA, Acyl|CHO Cells|Cricetulus|*Endoplasmic Reticulum|Plasma Membranes|Cholesterol|Digitonin|*Protein Domains | |
10438516 J. Biol. Chem. 1999 Humans|Mice|Animals|*Lymphocyte Activation|*Interleukin-16|Amino Acid Sequence|*Protein Binding|Binding Site|CD4 Antigens|Protein Conformation|CD4-Positive T-Lymphocytes|Histocompatibility Antigens Class II|Lymphocyte Reaction, Mixed|polypeptide C|Peptides|Models, Molecular|Base Sequence|Structure-Activity Relationship|Dimerization|Oligopeptides | |
10438626 J. Mol. Biol. 1999 Humans|RAD51 protein, human|*Rad51 Recombinase|Escherichia coli|*DNA|DNA, Single-Stranded|Heteroduplex DNA|Single-Stranded DNA-Binding Protein|DNA Repair|Replication Protein A|Rec A Recombinases|Nucleic Acid Conformation|Recombination, Genetic|Saccharomyces cerevisiae Proteins|Protein Binding | |
10438732 Blood 1999 Animals|*Endothelin-3|Kell Blood-Group System|PROS1 protein, human|Blood Proteins|DNA Primers|Metalloendopeptidases|Exons|Red Blood Cells|Endothelin-Converting Enzyme 1|Phenotype|phosphoramidon|Glycopeptides|DNA, Complementary|Point Mutation|Neutral Endopeptidase 24.11|*Blood Grouping and Crossmatching|TYRP1 protein, human|Membrane Glycoproteins | |
10438935 J. Immunol. 1999 *Vascular Cell Adhesion Molecule-1|ITGAD protein, human|*CD11 Antigens|*Integrin alpha Chains|ICAM3 protein, human|Cell Adhesion Molecules|ICAM1 protein, human|Intercellular Adhesion Molecule-1|Cell Adhesion|Integrin alpha4beta1|Lymphocyte Function-Associated Antigen-1|Antigens, CD|Macrophage-1 Antigen|CD18 Antigens|*CD8 Antigens|Leukocytes|Cell Movement|Binding Site | |
10440375 Nature 1999 Mice|Animals|*Synaptic Vesicles|Synapses|Synaptic Transmission|Presynaptic Terminals|Neurons|Hippocampus|Nerve Tissue Proteins|Patch-Clamp Techniques|GABA|Exocytosis|Intracellular Signaling Peptides and Proteins | |
10441588 Am. J. Hum. Genet. 1999 PMC1377988 Humans|*Alcoholism|Alcohol Dehydrogenase|*Polymorphism, Genetic|Aldehyde Dehydrogenase|Aldehyde Dehydrogenase, Mitochondrial|Genotype|Gene Frequency|Alleles|Ethanol|Homozygote|Asians|*Inactivation, Metabolic|Taiwan|ALDH2 protein, human | |
10444065 J. Cell Biol. 1999 PMC2150555 Humans|*Ribonuclease P|*Coiled Bodies|mitochondrial RNA-processing endoribonuclease|*Cell Nucleolus|RNA, Catalytic|rRNA Precursor|tRNA|Holoenzymes|Ribosomes|Protein Subunits | |
10444327 Genomics 1999 Humans|Mice|Animals|*Ubiquitin-Specific Proteases|In Situ Hybridization, Fluorescence|*Oncogene Proteins|Ubiquitin Thiolesterase|Endopeptidases|Base Sequence|Amino Acid Sequence|Chromosome Mapping|Ubiquitin|Cloning, Molecular|Ubiquitins|DNA, Complementary|Intron|Exon|GLB1 protein, human|beta-Galactosidase|Sequence Homology, Amino Acid|*Biological Phenomena | |
10444331 Genomics 1999 Rats|Humans|Animals|Cattle|Mice|Sardh protein, rat|SARDH protein, human|Sarcosinemia|*Sarcosine Dehydrogenase|*DNA, Complementary|*Amino Acid Metabolism, Inborn Errors|*Mitochondrial Diseases|Dmgdh protein, rat|Dimethylglycine Dehydrogenase|Amino Acid Sequence|Base Sequence|Chromosome Mapping|Exons|Cloning, Molecular|Mitochondrial Proteins|Sequence Homology, Amino Acid|Mitochondria | |
10444342 Mol. Genet. Metab. 1999 Child|Humans|Female|methionine synthase reductase|*Cobalamin|*Ferredoxin-NADP Reductase|MTR protein, human|5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase|Methylenetetrahydrofolate Reductase|*Spina Bifida|Folate|Polymorphism, Genetic|Allele Frequency|Neural Tube Defects|Genotype|Alleles|Genetic Predisposition to Disease|Mutation|Oxidoreductases Acting on CH-NH Group Donors|Odds Ratio|Mothers | |
10444453 Am. J. Physiol. 1999 Male|Female|Humans|Rabbits|Rats|Animals|*Tissue Distribution|*Sodium-Hydrogen Exchangers|*Cloning, Molecular|Blotting, Northern|Base Sequence|cDNA|Amiloride|Amino Acid Sequence|RNA|Transfections|Sodium|RNA, Messenger|Colon|Intestine, Small|Slc9a2 protein, rat | |
10444591 Genes Dev. 1999 PMC316920 *DNA Methylation|*Histone Deacetylases|NuRD Complex|Nucleosome|SIN3 Histone Deacetylase Complex|HDAC2 protein, human|Histone Deacetylase 2|DNA-Binding Proteins|Repressor Proteins|Histone Deacetylase, HDAC1|Amino Acid Sequence|Acetylation|Gene Silencing | |
10445031 Mol. Cell 1999 N-Ethylmaleimide-Sensitive Proteins|SNAREs|Soluble N-Ethylmaleimide-Sensitive Factor Attachment Proteins|Vesicular Transport Proteins|ATPase|Carrier Proteins|Amino Acid Sequence|Protein Binding|Membrane Fusion|Binding Sites|Models, Molecular|Adenosine Triphosphate | |
10445884 RNA 1999 PMC1369833 *Saccharomyces cerevisiae|*Substrate Specificity|Escherichia coli|RNA, Ribosomal, 16S|*tRNA|tRNA Methyltransferases|Saccharomyces cerevisiae Proteins|m(5)C rRNA methyltransferase|*Methyltransferases|RNA, Fungal|*Yeast, Dried|Genes, Fungal|Base Sequence|Methylation|Nucleic Acid Conformation|Amino Acid Sequence|Pre-tRNA|ORFs | |
10446041 Science 1999 *Signal Transduction|Integrins|Extracellular Matrix|Cell Adhesion|Cytoskeleton|Cell Division|Ion Channel|Receptors, Cell Surface | |
10446133 J. Biol. Chem. 1999 Animals|Humans|*Sodium|Amino Acid Transporter|*Amino Acid Transport Systems, Basic|Amino Acid Sequence|cDNA|proline transporter|Amino Acid Transport Systems, Neutral|Amino Acids|Carrier Proteins|Cloning, Molecular|Biological Transport|Xenopus laevis|Proline|Substrate Specificity|Oocytes|Glycine|RNA, Messenger|Kinetics | |
10446189 J. Biol. Chem. 1999 Mice|Animals|Humans|heparanase|*Glucuronidase|NIH 3T3 Cells|Heparitin Sulfate|Sequences, Amino Acid|Glycoside Hydrolases|Heparan Sulfate Proteoglycans|Peptides|Cloning, Molecular|Molecular Weight|Extracellular Matrix|cDNA|Tumor Cells, Cultured|Gel Permeation Chromatography|Transfections|Cell Membrane|Basement Membrane | |
10448034 J. Mol. Biol. 1999 *Mycobacterium tuberculosis|*Myo-Inositol-1-Phosphate Synthase|Protein Conformation|Amino Acid Sequence|mycothiol|Models, Molecular|Binding Sites|Crystallography, X-Ray|Sequence Homology, Amino Acid|Phosphatidylinositol|Inositol Phosphates|Glycopeptides|Cysteine | |
10448070 Biochem. Biophys. Res. Commun. 1999 Mice|Animals|*Phosphorylation|*Multiple Endocrine Neoplasia Type 2b|*Signal Transduction|Nck protein|GRB2 protein, human|GRB2 Adaptor Protein|DOK1 protein, human|Phosphoproteins|*Protein Binding|*Mutation|Proto-Oncogene Proteins c-ret|GDNF protein, human|Glial Cell Line-Derived Neurotrophic Factor|Multiple Endocrine Neoplasia Type 2a|Proto-Oncogene Proteins|ras Proteins|Glial Cell Line-Derived Neurotrophic Factor Receptors|Phosphatidylinositol 3-Kinases | |
10449415 EMBO J. 1999 PMC1171524 *Replication Protein A|*DNA, Single-Stranded|Single-Stranded DNA-Binding Protein|Amino Acid Sequence|Protein Structure, Tertiary|Binding Sites|Protein Binding|Crystallography, X-Ray|Dimerization|Models, Molecular|*Chromosome Structures|*Biochemical Phenomena | |
10449730 Proc. Natl. Acad. Sci. U.S.A. 1999 PMC22246 adenylyl cyclase type V|adenylyl cyclase 1|*Adenylyl Cyclases|*Heterotrimeric G-Proteins|GTP-Binding Protein gamma Subunits|GTP-Binding Protein beta Subunits|GTP-Binding Protein alpha Subunits, Gi-Go|Protein Binding|Amino Acid Sequence | |
10449753 Proc. Natl. Acad. Sci. U.S.A. 1999 PMC22269 Mice|Cattle|Animals|*SH2 Domain-Containing Protein Tyrosine Phosphatase|leptin receptor, human|*Receptors, Leptin|*Signal Transduction|PTPN11 protein, human|Protein Tyrosine Phosphatase, Non-Receptor Type 11|JAK2 protein, human|Janus Kinase 2|Phosphorylation|Protein Tyrosine Phosphatase, Non-Receptor Type 6|src Homology Domains|Carrier Proteins|Leptin | |
10449773 Proc. Natl. Acad. Sci. U.S.A. 1999 PMC22289 Mice|Animals|*Receptors, Cell Surface|Lectin, C-Type|Receptors, Immunologic|lectin B, Phytolacca americana|*Pokeweed Mitogens|Natural Killer Cells|Membrane Glycoproteins|Monocytes|*Myeloid Cells|Adaptor Proteins, Signal Transducing|Amino Acid Sequence|Cell Membrane|Isoforms|Cloning, Molecular | |
10449787 Proc. Natl. Acad. Sci. U.S.A. 1999 PMC22303 Humans|RE1-silencing transcription factor|Repressor Proteins|Corepressors|Transcription Factors|DNA-Binding Proteins|Nerve Tissue Proteins|Neurons|Promoter Regions, Genetic|Histone Deacetylases|Sodium Channel|NCOR1 protein, human|Nuclear Receptor Co-Repressor 1|*Gene Expression|Cell Differentiation|Zinc Finger Motif | |
10449790 Proc. Natl. Acad. Sci. U.S.A. 1999 PMC22306 Humans|Animals|Rats|*gamma Aminobutyric Acid Receptor|Receptors, GABA-A|gamma-Aminobutyric Acid|Amino Acid Sequence|DNA, Complementary|Polymerase Chain Reaction|Oocytes | |
10452521 FEBS Lett. 1999 Animals|Cattle|Humans|methionine sulfoxide reductase|*Methionine Sulfoxide Reductases|*Cloning, Molecular|Amino Acid Sequence|Oxidation-Reduction|N-acetylmethionine sulfoxide|Methionine|methionine sulfoxide|Sequence Homology, Amino Acid|Peptides|Cell Lines|Liver|Potassium Channel | |
10453075 Cell Death Differ. 1999 *Caspases|*Apoptosis|CASP3 protein, human|Caspase 3|APAF1 protein, human|Apoptotic Protease-Activating Factor 1|Caspase 9|Mitochondria|CASP2 protein, human|Caspase 2|Cytosol|Caspase 8|Caspase-7|Calpain|Cell Nucleus|Cytoplasm | |
10454565 Mol. Cell. Biol. 1999 PMC84557 Humans|*Cyclin-Dependent Kinases|CDC25A protein, human|*cdc25 Phosphatases|CCNE1 protein, human|*Cyclin E|*Ectopic Gene Expression|CDK2 protein, human|Cyclin-Dependent Kinase 2|Cyclin|CDC2-CDC28 Kinases|S Phase|*Oncogene Proteins|Cyclin-Dependent Kinase Inhibitor p21|Phosphorylation|Cyclin A | |
10454575 Mol. Cell. Biol. 1999 PMC84592 Animals|Mice|*Phosphorylation|*Cyclic Nucleotide Phosphodiesterases, Type 3|*Proto-Oncogene Proteins c-akt|Phosphatidylinositol 3-Kinases|B-insulin|*Insulin|3',5'-Cyclic-AMP Phosphodiesterases|Cyclic AMP Dependent Protein Kinase|Adipocytes|Signal Transduction|Enzyme Activation|Cyclic AMP|*Biotin|Serine | |
10454584 Mol. Cell. Biol. 1999 PMC84608 Humans|CDC25A protein, human|*cdc25 Phosphatases|*S Phase|E2F Transcription Factors|Transcription Factor DP1|Retinoblastoma-Binding Protein 1|CCNE1 protein, human|Cyclin E|Cell Cycle|Retinoblastoma Protein|E2F1 Transcription Factor|Retinoblastoma-Like Protein p130|E2F4 Transcription Factor|Phosphoproteins|Binding Sites|Cell Division|Genes, cdc | |
10455107 J. Biol. Chem. 1999 Animals|Humans|malonyl-CoA decarboxylase|Malonic aciduria|*Carboxy-Lyases|*Malonyl CoA|*Metabolism, Inborn Errors|*Methylmalonic Acid|*Cytosol|Fatty Acids|*Cytoplasm|Myocardium|Oxidation-Reduction|Skeletal Muscles|Acetyl-CoA|Heart|Amino Acid Sequence|Mitochondria|Cloning, Molecular|Lipid Metabolism | |
10455108 J. Biol. Chem. 1999 GAB1 protein, human|GAB2 protein, human|*Signal Transduction|PTPN11 protein, human|SHP2 Phosphatase|Phosphoproteins|SH2 Domains|SH2 Domain-Containing Protein Tyrosine Phosphatases|Phosphorylation|Protein Tyrosine Phosphatase, Non-Receptor Type 6|GRB2 Adaptor Protein|Phosphotyrosine|Phosphatidylinositol 3-Kinases|Protein Binding|EPO protein, human|Erythropoietin|Erythropoietin Receptor|Tyrosine | |
10455109 J. Biol. Chem. 1999 Animals|Humans|*Nucleosides|*Purine Nucleosides|pyrimidine|*Carrier Proteins|Pyrimidine Nucleosides|Membrane Transport Proteins|Biological Transport|*Sodium|Uridine|Amino Acid Sequence|*Amino Acids|Xenopus laevis|Kinetics | |
10455115 J. Biol. Chem. 1999 Humans|Mice|Animals|*Selenocysteine|*Thioredoxin Reductase|*Redox|TXN protein, human|Thioredoxin|*Cell Signaling|Amino Acid Sequence|*Mammals|*Biochemical Phenomena|Reactive Oxygen Species | |
10455134 J. Biol. Chem. 1999 *B-Cell-Specific Activator Protein|*Promoter Regions, Genetic|*B-Lymphocytes|Transcription Factors|DNA-Binding Proteins|Nuclear Proteins|Binding Sites|protein-tyrosine kinase p55(blk)|src-Family Kinases|Transcription, Genetic|Base Sequence|Transfection|*Genes, src|Regulatory Regions|Genes, Reporter|Protein Binding|Lymphocyte Activation|Hematopoiesis | |
10455175 J. Biol. Chem. 1999 Chlorocebus aethiops|Mice|Animals|Rats|Humans|*sPLA(2)|Cloning, Molecular|cDNA|Amino Acid Sequence|Chromosome|Sequence Homology, Amino Acid|Phospholipids|Substrate Specificity|Hydrolysis|mRNA|COS-7 Cells | |
10455177 J. Biol. Chem. 1999 Animals|Dogs|INSR protein, human|*Receptor, Insulin|IRS2 protein, human|*Insulin Receptor Substrate 1|*Drosophila|*Cell Survival|Phosphoproteins|*Antigens, CD|SH2 Domain|Phosphorylation|Phosphotyrosine|Adaptor Proteins, Signal Transducing|Signal Transduction|Phosphatidylinositol 3-Kinases|Amino Acid Sequence|JAK2 protein, human|Janus Kinase 2|PTPN11 protein, human | |
10455184 J. Biol. Chem. 1999 *NADPH Oxidase|*Tetratricopeptide Repeat|4-ethoxymethylene-2-phenyl-2-oxazoline-5-one|*Phagocyte|neutrophil cytosol factor 67K|*Phosphoproteins|Superoxide|rac GTP-Binding Proteins|Neutrophils | |
10457025 Development 1999 Mice|Animals|*Drosophila|*Axin Protein|*Wnt Signaling Pathway|Drosophila Proteins|Wnt1 Protein|Armadillo Domain Proteins|CTNNB1 protein, human|beta Catenin|Drosophila melanogaster|Transcription Factors|Trans-Activators|Adaptor Proteins, Signal Transducing|Phosphoproteins|Proto-Oncogene Proteins|Carrier Proteins|Dishevelled Proteins|Protein-Serine-Threonine Kinases|Gene Expression Regulation, Developmental | |
10458166 Nature 1999 Animals|SMAD2 protein, human|Smad2 Protein|UBB protein, human|*Ubiquitin|SMAD4 protein, human|Smad4 Protein|TGFbeta|*Embryonic Pattern Formation|Bone Morphogenetic Proteins|Trans-Activators|Signal Transduction|E3 Ubiquitin Ligase|Receptors, Transforming Growth Factor beta|Smad7 Protein|Smad1 Protein|Smad5 Protein|Protein-Serine-Threonine Kinases|Phosphorylation | |
10458606 Cell 1999 Animals|Hedgehog Proteins|Signal Transduction|Drosophila Proteins|Drosophila melanogaster|Transcription Factors|*Cell Nucleus|Gene Expression Regulation, Developmental|DNA-Binding Proteins|Kinesin|Cyclic AMP-Dependent Protein Kinases|Repressor Proteins|Protein-Serine-Threonine Kinases|*Protein Transport|Zinc Fingers|Phosphorylation|Activation, Transcriptional|Export, Nuclear|*Cell Movement | |
10459009 J. Cell Biol. 1999 PMC2156142 Animals|Swine|Drosophila Proteins|Drosophila melanogaster|Drosophila|Genes, Insect|Wings, Animal|Amino Acid Sequence|Receptors, Notch|ras Proteins|Mutations|Membrane Proteins|Carrier Proteins|Signal Transduction|Sequence Homology, Amino Acid|Genes, Suppressor|Saccharomyces cerevisiae|Cloning, Molecular|notch protein, Drosophila|Rab6 protein, Drosophila | |
10460157 Biochemistry 1999 Animals|Humans|*Proliferating Cell Nuclear Antigen|*Replication Protein A|*Cell Extracts|Base Excision Repair|*DNA|DNA-(Apurinic or Apyrimidinic Site) Lyase|Deoxyribonuclease IV (Phage T4-Induced)|DNA Polymerase beta|DNA Polymerase delta|RepB' protein, E coli|*Escherichia coli Proteins|DNA Ligases|DNA Damage|Endonucleases|DNA Ligase ATP | |
10461880 J. Neurochem. 1999 Animals|Rats|Humans|*Neuropeptide Y|*5' Untranslated Region|*Alternative Splicing|Receptors, Neuropeptide Y|cDNA|Exons|Base Sequence|*Gene Expression|Amino Acid Sequence|Cloning, Molecular|Brain | |
10462554 Mol. Pharmacol. 1999 Humans|leukotriene D4 receptor|HEK293 Cells|*Receptors, Leukotriene|Leukotriene D4|cysteinyl-leukotriene|Leukotrienes|*Cloning, Molecular|Leukotriene Antagonists|Leukotriene C4|LTE4|montelukast|Acetates|Membrane Proteins|Cysteine|Quinolines|Sequence Homology, Amino Acid|Binding, Competitive|pranlukast | |
10462698 J. Neurosci. Res. 1999 Animals|Humans|Mice|Rats|In Situ Hybridization, Fluorescence|connexin 36|*Junction Protein, Gap|*Brain|Base Sequence|Chromosome Mapping|Eye Proteins|Cloning, Molecular|Amino Acid Sequence|Nerve Tissue Proteins|Sequence Alignment|DNA, Complementary|Central Nervous System|Sequence Homology, Amino Acid|RNA, Messenger|Intron|Neurons | |
10464285 J. Biol. Chem. 1999 2',5'-oligoadenylate|*Catalytic Domain|*Synthetases|*Oligoribonucleotides|*Adenine Nucleotides|2',5'-Oligoadenylate Synthetase|Amino Acid Sequence|Double-Stranded RNA|Dimerization|Mutagenesis, Site-Directed|Catalysis|Isozymes | |
10464296 J. Biol. Chem. 1999 Animals|Rats|Humans|Cricetinae|HNK-1 sulfotransferase|Kinetics|Chst10 protein, rat|*Sulfotransferases|heparitin sulfotransferase|estrone sulfotransferase|*Binding Sites|*Mutagenesis, Site-Directed|Amino Acid Sequence|Glucuronic Acid|cDNA|Cloning, Molecular|CHO Cells|CD57 Antigens|Sequence Homology, Amino Acid|Polysaccharides | |
10465784 Genes Dev. 1999 PMC316957 *Signal Transduction|Tifab protein, human|TRAF6|NF-kappa B|Receptors, IL1|Adaptor Proteins, Signal Transducing|Toll-Like Receptors|Myeloid Differentiation Factor 88|Receptors, Immunologic|Receptors, Cell Surface|Interleukin-1 Receptor-Associated Kinases|Membrane Glycoproteins|Antigens, Differentiation|Drosophila Proteins|Protein Kinases|Lipopolysaccharides|Interleukin-1 | |
10466419 Clin. Genet. 1999 Humans|Chlorocebus aethiops|Animals|*Mucopolysaccharidosis I|*Iduronidase|Mutation|COS-7 Cells|Transfections | |
10467273 Am. J. Hematol. 1999 Humans|Child|*Mutation, Missense|*Glycoprotein|Exon|Base Sequence|RNA Splicing|Rh-Hr Blood-Group System|Membrane Glycoproteins|Amino Acid Sequence|Blood Proteins|Introns|Mutation|Haemolytic Anaemia|RHAG protein, human | |
10468558 Proc. Natl. Acad. Sci. U.S.A. 1999 PMC17838 Animals|Rats|Humans|*Thiamine Pyrophosphate|2-hydroxyphytanoyl-coenzyme A lyase|*Carbon|*Carbon-Carbon Lyases|fatty aldehyde|*Acids, Fatty|Phytanic Acid|HACL1 protein, human|*Enoyl-CoA Hydratase|*Oxidation-Reduction|Peroxisomes|*Cloning, Molecular|formyl-coenzyme A|Acyl Coenzyme A|Aldehydes|Microbodies|Lyases|*Catalysis | |
10468583 Proc. Natl. Acad. Sci. U.S.A. 1999 PMC17863 Male|PTEN protein, human|*PTEN Phosphohydrolase|*Genes, Tumor Suppressor|Phosphatidylinositol-3-OH Kinase|Protein-Serine-Threonine Kinases|Amino Acid Sequence|Mutations|Signal Transduction|Point Mutations|Glioblastoma|Tumor Cells, Cultured|Transfection|Cell Line | |
10468607 Proc. Natl. Acad. Sci. U.S.A. 1999 PMC17887 *MHC Class I Molecules|*Endosomes|Histocompatibility Antigens Class II|Antigen Processing|Plasma Membrane|*Peptides|Endocytosis|Cross-Priming|Endoplasmic Reticulum|Biological Transport|B-Lymphocytes|Green Fluorescent Proteins|F Protein Measles Virus | |
10468875 Br. J. Haematol. 1999 Humans|F8 protein, human|*Factor VIII|*Hemophilia A|Activated Factor VIII|Factor IXa|Factor X|Protein Binding|Binding Site|*Hemostatics|cancer procoagulant|Neoplasm Proteins|Mutation|Cysteine Endopeptidases | |
10469124 Eur. J. Biochem. 1999 Mice|Animals|Humans|*Phospholipase C gamma2|*Receptor, Collagen|*Blood Platelets|phosphoprotein, 75-kDa|*Phosphoproteins|SLP-76 signal Transducing adaptor proteins|*Adaptor Proteins, Signal Transducing|Tyrosine Kinase, SYK|*Receptors, IgG|collagen-related peptide|Carrier Proteins|src Homology Domains|Platelet Activation|Phosphorylation|Protein-Tyrosine Kinases|Intracellular Signaling Peptides and Proteins|src-Family Kinases|*Glycoprotein | |
10469173 Genes Cells 1999 Humans|*Caspases|*Vimentin|*Apoptosis|CASP3 protein, human|Caspase 3|CASP8 protein, human|Caspase-8|Caspase Inhibitors|Amino Acid Chloromethyl Ketones|fas Receptor|Proto-Oncogene Proteins c-bcl-2|Poly(ADP-ribose) Polymerases|DNA Fragmentation|Mitochondria|Cysteine Proteinase Inhibitors|Jurkat Cells | |
10469573 Curr. Biol. 1999 Cattle|Animals|NOS3 protein, human|*Nitric Oxide Synthase Type III|*Proto-Oncogene Proteins c-akt|Vascular Endothelial Growth Factor A|Endothelial Cells|Phosphorylation|Vascular Endothelial Growth Factors|Nitric Oxide Synthase|Signal Transduction|Proto-Oncogene Proteins|Endothelium, Vascular|Nitric Oxide|Serine|Wortmannin | |
10469599 Curr. Biol. 1999 SIRPA protein, human|*Receptors, Immunologic|*Antigens, Differentiation|SH2 Domain-Containing Protein Tyrosine Phosphatases|Tyrosine Phosphatase, SHP-1|Phosphorylation|Membrane Glycoproteins|*Macrophages|Signal Transduction|Protein Tyrosine Phosphatase, Non-Receptor Type 11|Neural Cell Adhesion Molecules|Integrins|src-Family Kinases|SLP-76 signal Transducing adaptor proteins|src Homology Domain|Focal Adhesion Protein-Tyrosine Kinases|Neural Cell Adhesion Molecule L1|Adaptor Proteins, Signal Transducing | |
10469646 EMBO J. 1999 PMC1171540 Animals|*Drosophila|*Receptor, Frizzled|SLK protein, human|*Protein-Serine-Threonine Kinases|*Signal Transduction|Drosophila Proteins|Wings, Animal|Dishevelled Proteins|Adaptor Proteins, Signal Transducing|Cell Polarity|Mitogen-Activated Protein Kinases|Phosphoproteins|Intracellular Signaling Peptides and Proteins|Receptors, G-Protein-Coupled|Membrane Proteins|JNK Mitogen-Activated Protein Kinases|Eyes|misshapen protein, Drosophila | |
10469659 EMBO J. 1999 PMC1171553 *Integral Membrane Proteins|*Intracellular Membranes|*Mitochondria|Saccharomyces cerevisiae|Saccharomyces cerevisiae Proteins|Carrier Proteins|Mitochondrial Membrane Transport Proteins|Mitochondrial Proteins|Membrane Transport Proteins|Mitochondrial ADP, ATP Translocases|Biological Transport|Protein Transport|Protein Binding|Amino Acid Sequence|Cytosol|TIM22 protein, S cerevisiae | |
10470034 Trends Biochem. Sci. 1999 Chlorocebus aethiops|Animals|*Signal Transduction|p21-Activated Kinases|Cell Cycle Proteins|cdc42 GTP-Binding Protein|Cytoskeleton|rac GTP-Binding Proteins|rho GTPases|Enzyme Activation|Rho Guanine Nucleotide Exchange Factors|Phosphorylation|Protein Binding|COS Cells|Cell Polarity | |
10470077 Nat. Med. 1999 Mice|Animals|Humans|*Apyrase|Heart Transplantation|Tissue Donors|Platelet Activation|Platelets|Thrombosis|Adenosine Diphosphate|Hemostasis|Adenosine Triphosphate|Antigens, CD|*Blood Coagulation Disorders|Adenosine Triphosphatases|Blood Coagulation|Endothelium, Vascular | |
10471399 Biochem. Biophys. Res. Commun. 1999 Humans|Female|Rats|Animals|Pregnancy|*Sodium-Coupled Vitamin C Transporters|Organic Anion Transporters, Sodium-Dependent|Symporters|Ascorbic Acid|Amino Acid Sequence|Sodium|Biological Transport|*Cloning, Molecular|cDNA|Kinetics|cDNA Library|Transfections|*Placenta | |
10471499 Nat. Genet. 1999 Humans|Animals|HeLa Cells|*Histone Deacetylases|trichostatin A|Hydroxamic Acids|DNA Methylation|Methyl-CpG-Binding Protein 2|Repressor Proteins|Transcription Factors|Transcription, Genetic|Histones|Gene Silencing|DNA|Protein Binding | |
10471742 Nucleic Acids Res. 1999 PMC148628 Animals|*RNA Polymerase I|Transcription Factor|Pol1 Transcription Initiation Complex Proteins|DNA-Binding Proteins|Transcription, Genetic|rDNA|Promoter Regions, Genetic|Nuclear Proteins|*DNA Repair|Ku Autoantigen|Gene Expression Regulation|RNA, Ribosomal|*Mammals|Holoenzymes | |
10473346 Crit. Rev. Biochem. Mol. Biol. 1999 *Replication Protein A|*Eukaryotes|DNA Replication|Nucleotide Excision Repair|DNA, Single-Stranded|Single-Stranded DNA-Binding Protein|DNA Damage|*Eukaryotic Cells|Phosphorylation|Protein Binding|RepB' protein, E coli|*Escherichia coli Proteins|DNA|*Chromosome Structures | |
10473551 J. Biol. Chem. 1999 CTNNB1 protein, human|*beta Catenin|IQ motif containing GTPase activating protein 1|CTNNA1 protein, human|alpha Catenin|ras GTPase-Activating Proteins|CDH1 protein, human|E Cadherin|Cell Adhesion|cdc42 GTP-Binding Protein|Carrier Proteins|Cell Cycle Proteins|RHOA protein, human|rhoA GTP-Binding Protein|Cell Membrane|Protein Binding|Trans-Activators|GTPgammaS | |
10473558 J. Biol. Chem. 1999 *src Homology Domains|*Phospholipase C gamma1|Phosphorylation|EGFR protein, human|Receptors, Epidermal Growth Factor|Phosphotyrosine|Protein Binding|Tyrosine|Isoenzymes|Mutagenesis, Site-Directed | |
10473568 J. Biol. Chem. 1999 Humans|*UDP Galactose|xylosylprotein 4-beta-galactosyltransferase|*Xylose|*Galactose|*Proteoglycan|*Galactosyltransferases|UDP-galactose xylose galactosyltransferase|N-acetyllactosaminide alpha-1,3-galactosyltransferase|Amino Acid Sequence|Cloning, Molecular|Sequence Homology, Amino Acid|Ehlers-Danlos Syndrome|Cell Line | |
10473618 J. Biol. Chem. 1999 *RNA Polymerase III|*Saccharomyces cerevisiae|TFIIIB|Transcription Factors, TFIII|Transcription, Genetic|Saccharomyces cerevisiae Proteins|Transcription Factors|Gene Expression Regulation, Fungal|TATA-Box Binding Protein|DNA, Fungal|RNA Polymerase II|DNA-Binding Proteins|Genes, Fungal|Promoter Regions, Genetic|RNA Polymerases|Base Sequence | |
10473623 J. Biol. Chem. 1999 Animals|*Xenopus laevis|*Activin|SMAD2 protein, human|Smad2 Protein|SMAD4 protein, human|Smad4 Protein|Smad Proteins|SMAD3 protein, human|Smad3 Protein|Transforming Growth Factor beta|Xenopus Proteins|Trans-Activators|*Embryogenesis|Inhibins|Transductions, Signal|Binding Sites|Protein Binding|Forkhead Transcription Factors | |
10476967 Nature 1999 Mice|Animals|*Cell Differentiation|*Signal Transduction|*Pancreas|Receptors, Notch|Basic Helix-Loop-Helix Transcription Factors|Immunoglobulin J Recombination Signal Sequence-Binding Protein|Homeodomain Proteins|Membrane Proteins|Nerve Tissue Proteins|Receptor, Notch1|Nuclear Proteins|Islets of Langerhans|Trans-Activators|Endocrine Cells|Progenitor Cells|Phenotype | |
10477300 Development 1999 Animals|Hedgehog Proteins|*Protein Kinase A|*Drosophila|*Phosphorylation|*Proteolysis|Signal Transduction|Drosophila Proteins|Transcription Factors|DNA Binding Protein|Protein Processing, Post-Translational | |
10477686 Blood 1999 Mice|Animals|*Interleukin 3 Receptor|IL3 protein, human|*Interleukin-3|Erythropoietin Receptor|IL3RA protein, human|*Interleukin-3 Receptor alpha Subunit|*Cell Proliferation|Signal Transduction|Cell Line|Cell Division|Transfection | |
10477722 Blood 1999 Humans|Mice|Rats|Animals|*Receptors, IL-5|IL3 protein, human|*Interleukin-3|*Granulocyte-Macrophage Colony-Stimulating Factor|*Phosphorylation|*Serine|14-3-3 Proteins|CSF2RA protein, human|Receptors, Granulocyte-Macrophage Colony-Stimulating Factor|CSF2RB protein, human|*Cytokine Receptor Common beta Subunit|Receptors, Interleukin-3|*Protein Binding|Receptors, Interleukin|Interleukin-5|Signal Transduction|Binding Site|Amino Acid Sequence | |
10479448 Dev. Biol. 1999 Animals|*Bone Morphogenetic Protein 1|*Tolloid-Like Metalloproteinases|chordin|Intercellular Signaling Peptides and Proteins|Glycoproteins|Bone Morphogenetic Proteins|Metalloproteases|Metalloendopeptidases|Amino Acid Sequence|Drosophila|*Mammals|TGFbeta|Procollagen|Mammalian Embryos|Morphogenesis | |
10479480 Mol. Genet. Metab. 1999 Chlorocebus aethiops|Animals|Humans|Rats|*DNA, Complementary|*Acyl Coenzyme A|*Synthetase|long-chain-fatty-acid-CoA ligase|Synthetases, Acyl CoA|Amino Acid Sequence|*Liver|Peroxisomes|Adrenoleukodystrophy|Acids, Fatty|Saccharomyces cerevisiae Proteins|COS-1 Cells|Endoplasmic Reticulum|Transfection|Cloning, Molecular|Microbodies|Repressor Proteins | |
10480354 Hum. Genet. 1999 Humans|*Exostoses, Multiple Hereditary|EXTL2 protein, human|N-Acetylglucosaminyltransferases|EXTL3 protein, human|*DNA Mutational Analysis|EXTL1 protein, human|Mutation|Exon|Pedigree|Frameshift Mutation|Tumor Suppressor Proteins|*Chinese|Intron|Mutations, Missense|Stop Codons, Premature|Heterogeneities, Genetic|Membrane Proteins|Europe | |
10480595 Diabetes 1999 *Insulin Secretion|*Glucose|Diabetes Mellitus, Type 2|*Cytoplasmic Granules|Insulin|Exocytosis|Islets of Langerhans|SNARE Proteins|Syntaxin|Synaptobrevin|Soluble N-Ethylmaleimide-Sensitive Factor Attachment Protein|*Secretion | |
10480625 Diabetes 1999 Mice|Humans|Animals|*Insulin|*Glucose-6-Phosphatase|*Catalytic Domain|Diabetes Mellitus, Type 2|*Promoter Regions, Genetic|*Insulin, Regular, Human|Transcription, Genetic|Response Elements|Base Sequence|Binding Sites|Glucose|Hepatocyte Nuclear Factor 1|Forkhead Transcription Factors|Protein Binding|Gene Expression Regulation, Enzymologic|Chloramphenicol O-Acetyltransferase | |
10480903 J. Biol. Chem. 1999 FGFR1 protein, human|*Receptor, Fibroblast Growth Factor, Type 1|*Translocation, Genetic|*Myeloproliferative Disorder|Oncogene Proteins, Fusion|Tyrosine Kinase|DNA-Binding Proteins|Zinc Fingers|Signal Transduction|Transcription, Genetic|Phosphorylation|Amino Acid Sequence | |
10480933 J. Biol. Chem. 1999 PDPK1 protein, human|*3-Phosphoinositide-Dependent Protein Kinases|*Phosphorylation|Mitogen-Activated Protein Kinases|ribosomal protein S6 kinase, 90kDa, polypeptide 3|Ribosomal Protein S6 Kinases, 90-kDa|AKT1 protein, human|Protein Kinase B|Signal Transduction Pathways|Enzyme Activation|Amino Acid Sequence|Serine|Binding Sites | |
10480952 J. Biol. Chem. 1999 Humans|*trans-Golgi Network|*Chimera|invariant chain|Antigens, Differentiation, B-Lymphocyte|*Class II Major Histocompatibility Molecules|*HLA-DR|Antigen Processing|Golgi Apparatus|Cell Membrane|Endocytosis|tyrosine O-sulfate|*Tyrosine|Antigen Presenting Cells|Cell Line|Cell Compartmentation|B-Lymphocytes|Cell Line, Transformed|Biological Transport | |
10481010 Science 1999 Animals|*Proteasome Endopeptidase Complex|*CLOCK Proteins|*Cytoplasm|Period Circadian Proteins|Drosophila|Photoreceptor Cells, Invertebrate|Drosophila Proteins|Ubiquitins|Leupeptins|Ubiquitin|Biological Clocks|Circadian Rhythm|Nuclear Proteins|Cysteine Proteinase Inhibitors|Darkness|Cysteine Endopeptidases|Light|timeless protein, Drosophila | |
10481074 FEBS Lett. 1999 Animals|CTNNB1 protein, human|*beta Catenin|*Phosphorylation|*Axin Protein|*Glycogen Synthase Kinase 3|*Protein-Serine-Threonine Kinases|Wnt Proteins|Binding Protein|Trans-Activators|Repressor Proteins|Xenopus Proteins|Calcium-Calmodulin-Dependent Protein Kinases|Protein Binding|Adenomatous Polyposis Coli Protein|Xenopus laevis|Amino Acid Sequence|Peptides|Adaptor Proteins, Signal Transducing | |
10484769 Hum. Mol. Genet. 1999 Humans|MTR protein, human|Arakawa syndrome 2|*5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase|methionine synthase reductase|*Cobalamin|*Folate|*Reductase|*Ferredoxin-NADP Reductase|Hypermethioninemia|*Amino Acid Metabolism, Inborn Errors|Methylcobalamin Deficiency, CblG Type|*Metabolism, Inborn Errors|Homocystinuria|Anemia, Megaloblastic|cDNA|Hyperhomocysteinemia|Methionine|Mutations | |
10484776 Hum. Mol. Genet. 1999 Humans|Animals|Primary hyperoxaluria type 2|*Hyperoxaluria, Primary|*Hydroxypyruvate Reductase|glyoxylate reductase|Alcohol Oxidoreductases|Mutations|Genetic Testing|Exons|Oxalates|Homozygote|cDNA|Heterozygote|Introns|Stop Codon, Premature|Transfection|Expressed Sequence Tag | |
10484778 Hum. Mol. Genet. 1999 Humans|Animals|Chlorocebus aethiops|*Ectodysplasins|*Membrane Protein|*Tumor Necrosis Factor-alpha|Ectodermal Dysplasia, Anhydrotic|Amino Acid Sequence|*Cytoskeleton|Isoforms|Ligands|Mutation|COS-1 Cells|Ectoderm|Ectodermal Dysplasia 1, Anhidrotic | |
10484781 Hum. Mol. Genet. 1999 Cricetinae|Animals|*Menkes Kinky Hair Syndrome|*Copper|*Leucine|ATP7A protein, human|*Copper-Transporting ATPase|*Plasma Membrane|Cation Transport Proteins|Adenosine Triphosphatases|trans Golgi Network|Golgi Apparatus|Endosomes|Biological Transport|Mutation|Amino Acid Sequence|CHO Cells | |
10485457 Cancer Res. 1999 Humans|*Microsatellite Instability|*Frameshift Mutation|*T Cell Transcription Factor 4|*Colorectal Cancers|CTNNB1 protein, human|beta Catenin|Transcription Factor|Colonic Neoplasms|Adenomatous Polyposis Coli|Trans-Activators|Mutation|Microsatellite Repeats|Cell Transformation, Neoplastic | |
10485710 Nature 1999 AKT1 protein, human|*Proto-Oncogene Proteins c-akt|NF-kappa B kinase|CHUK protein, human|IKK beta|*Signal Transduction|*Tumor Necrosis Factor-alpha|NF-kappa B|Phosphatidylinositol-3-OH Kinase|I-kappa B Proteins|Phosphorylation|*Gene Expression Regulation|RELA protein, human|Transcription Factor RelA|Proto-Oncogene Proteins|Wortmannin | |
10485843 Genes Dev. 1999 PMC316985 Humans|*Transforming Growth Factor beta|SMAD2 protein, human|Smad2 Protein|SMAD3 protein, human|Smad3 Protein|*Smad Proteins|SMAD4 protein, human|Smad4 Protein|*Transductions, Signal|Trans-Activators|Proto-Oncogene Proteins|Transcription, Genetic|Promoter Regions, Genetic|Transcriptional Activation|Transforming Growth Factor beta Receptor|DNA|Binding Sites|Cell Nucleus | |
10485845 Genes Dev. 1999 PMC316998 Animals|*Drosophila|*Histone Deacetylase|Transcription Factors|Repressor Proteins|Drosophila Proteins|Basic Helix-Loop-Helix Transcription Factors|Histone Deacetylase 1|Gene Expression Regulation, Developmental|Embryo, Nonmammalian|Co-Repressor Proteins|groucho protein, Drosophila|Rpd3 protein, Drosophila | |
10485890 Proc. Natl. Acad. Sci. U.S.A. 1999 PMC17947 Animals|NGF protein, human|*Nerve Growth Factor|trkA Receptor|Receptors, Nerve Growth Factor|p75 Neurotrophin Receptor|Neurotrophin 3|Proto-Oncogene Proteins|*Zinc Finger|Signal Transduction|Brain-Derived Neurotrophic Factor|Protein Binding|Amino Acid Sequence|Transfections | |
10485905 Proc. Natl. Acad. Sci. U.S.A. 1999 PMC17962 opsonin receptor|glycoprotein 340|*Pulmonary Surfactant-Associated Protein D|*Receptors, Immunologic|DMBT1 protein, human|*Receptors, Cell Surface|Pulmonary Surfactants|Pulmonary Surfactant-Associated Protein A|Macrophages, Alveolar|Lung|Amino Acid Sequence|Cloning, Molecular|Proteolipids|cDNA|Macrophages|Phagocytosis | |
10485994 J. Membr. Biol. 1999 Animals|Humans|Female|Pregnancy|*Cationic Amino Acid Transporters|*Trophoblasts|Amino Acids|*Placenta|Leucine|Biological Transport|Carrier Proteins|Xenopus laevis|Alanine|Amino Acid Sequence|cDNA|Membrane Proteins|Oocytes|Sodium|Cloning, Molecular|cRNA|Cell Line|Choriocarcinoma | |
10486198 Exp. Neurol. 1999 Mice|Animals|neurotrophin 4|BDNF protein, human|*Brain-Derived Neurotrophic Factor|*Neurotrophin 3|NTF3 protein, human|*Signal Transduction|tropomyosin-related kinase-B, human|Receptor, trkB|Receptor Protein-Tyrosine Kinases|Phosphorylation|Receptors, Nerve Growth Factor|PLC gamma1|Receptor, trkC|Receptor, Ciliary Neurotrophic Factor|Calcium-Calmodulin-Dependent Protein Kinases|Adaptor Proteins, Vesicular Transport|Shc Signaling Adaptor Proteins|Tyrosine | |
10486279 Biochem. Biophys. Res. Commun. 1999 Humans|carnitine octanoyltransferase|*Carnitine Acyltransferases|pristanic acid|*Fatty Acids|propionyl-coenzyme A|CoA, Acyl|Carnitine O-Palmitoyltransferase|Peroxisomes|Oxidation-Reduction|*Cloning, Molecular|Carnitine Acetyltransferase|Mitochondrion|Carnitine|Acetyl-CoA|Acyltransferases|Microbodies|Amino Acid Sequence|Cells, Cultured | |
10487695 J. Clin. Endocrinol. Metab. 1999 Humans|Child|Infant, Newborn|*Congenital Hypothyroidism|*Iodides|sodium-iodide symporter|Symporters|Homozygote|Heterozygote|Exon|*Metabolism, Inborn Errors|Mutation|Pedigree|Thyroid Gland|Transfection|Membrane Proteins|Introns|Genotype|Biological Transport|DNA|Sodium | |
10487827 Am. J. Pathol. 1999 PMC1866892 Humans|*Carcinoma, Hepatocellular|CTNNB1 protein, human|*beta Catenin|*Liver Neoplasms|Trans-Activators|Immunohistochemistry|*Cell Proliferation|Exon|Ki-67 Antigen|Cyclin D1|Mutations|Cell Nucleus|Cell Division | |
10487978 Front. Biosci. 1999 *Phosphorylase Kinase|Calmodulin|Phosphorylation|Amino Acid Sequence|Glycogen Phosphorylase|Glycogen|Protein Subunits|Molecular Weight | |
10488065 J. Biol. Chem. 1999 Humans|*Sphingosine-1-Phosphate Receptors|HEK293 Cells|lysophosphatidic acid|Lysophospholipids|sphingosine 1-phosphate|*G-Protein-Coupled Receptors|sphingosine phosphorylcholine|Sphingosine|*Heterotrimeric G-Proteins|Receptors, Lysophospholipid|Signal Transduction|Receptors, Cell Surface|I-kappa B Proteins|DNA-Binding Proteins|Immediate-Early Proteins|NF-KappaB Inhibitor alpha|Pertussis Toxin|Cell Membrane | |
10488122 J. Biol. Chem. 1999 Rats|Animals|Humans|sphingosine 1-phosphate|*Lysophospholipids|lysophosphatidic acid|Lysophosphatidic Acid Receptor|Sphingosine|Receptors, Cell Surface|*Cloning, Molecular|Ligands|Signal Transduction|Amino Acid Sequence|Mitogen-Activated Protein Kinases|cDNA|Cyclase, Adenylyl|Calcium | |
10488343 Mol. Cell 1999 Animals|*Caenorhabditis elegans|*MAP Kinase Kinase Kinase|Caenorhabditis elegans Proteins|Signal Transduction|Transcription Factors|Mitogen-Activated Protein Kinases|High Mobility Group Proteins|Protein-Serine-Threonine Kinases|Phosphorylation|DNA-Binding Proteins|Wnt Proteins|Membrane Proteins|beta Catenin|Trans-Activators|Downregulation|Sequence Homology, Amino Acid|Amino Acid Sequence|Protein Kinase | |
10489353 Virology 1999 Humans|*Active Transport, Cell Nucleus|Nucleocytoplasmic Transport Proteins|RNA-Binding Proteins|Nuclear Proteins|*RNA Transport|RNA, Messenger|Mason Pfizer monkey virus|RNA, Viral|Cell Nucleus|Saccharomyces cerevisiae|RNA, Nuclear | |
10490026 Nature 1999 Humans|CASP3 protein, human|*Caspase 3|Caspases|caspase-activated deoxyribonuclease|Deoxyribonucleases|DNA Fragmentation|Apoptosis|*Heterochromatin|DFFB protein, human|Cell Nucleus|Nucleosomes|Chromatin|Apoptosis Regulatory Proteins|Jurkat Cells|Cell Line|Poly-ADP-Ribose Binding Proteins | |
10490027 Nature 1999 *Proto-Oncogene Proteins c-raf|*Signal Transduction|Raf Kinase Inhibitor Protein|Phosphorylation|Extracellular Signal Regulated Kinases|Androgen-Binding Protein|Carrier Proteins|Proto-Oncogene Proteins|Secretoglobins|Phospholipid Transfer Proteins|Genes, Reporter|Downregulation | |
10490030 Nature 1999 Animals|Rats|Humans|*Receptor, trkA|NGF protein, human|*Nerve Growth Factor|Receptors, Nerve Growth Factor|Protein Binding|Protein Conformation|Binding Site|Amino Acid Sequence|Phosphorylation|Proto-Oncogene Proteins|Dimerization|Models, Molecular|Signal Transduction|PC12 Cells | |
10490098 Cell 1999 Animals|*Cell Polarity|Drosophila|*Cadherins|Wings, Animal|Drosophila Proteins|Frizzled Receptors|Body Patterning|Receptors, G-Protein-Coupled|Dishevelled Proteins|Membrane Proteins|Phosphoproteins|Adaptor Proteins, Signal Transducing|Signal Transduction|Gene Expression Regulation, Developmental | |
10490103 Cell 1999 *Dimerization|Receptor, Fibroblast Growth Factor, Type 1|Protein Conformation|Receptor, Fibroblast Growth Factor, Type 2|Binding Site|Protein Binding|Amino Acid Sequence|Models, Molecular|Signal Transduction|Heparin | |
10490848 Oncogene 1999 ribosomal protein S6 kinase, 70kD, polypeptide 2|*Proto-Oncogene Proteins c-akt|Phosphatidylinositol 3-Kinases|p70 S6 Kinase|Signal Transduction|Phosphorylation|Mitogen-Activated Protein Kinases|Wortmannin|Rapamycin|*Cell Nucleus|Cloning, Molecular | |
10490993 J. Immunol. 1999 Cricetinae|Humans|Mice|Animals|*Mycobacterium tuberculosis|CHO Cells|Cricetulus|*Toll-Like Receptors|lipoarabinomannan|Lipopolysaccharides|Toll-Like Receptor 2|Toll-Like Receptor 4|Lipopolysaccharide Receptors|Macrophages|Membrane Glycoproteins|NF-kappa B|Signal Transduction|Mycobacterium bovis|Tumor Necrosis Factor-alpha|Drosophila Proteins | |
10491328 Biochem. Biophys. Res. Commun. 1999 Humans|Chlorocebus aethiops|Animals|Mice|*Acetylglucosamine|carbohydrate sulfotransferases|*Sulfotransferases|Amino Acid Sequence|cDNA|Base Sequence|*Intestines|Cloning, Molecular|Chromosome Mapping|COS Cells|Sequence Homology, Amino Acid|*Mammals|Sulfates|Substrate Specificity|Transfection | |
10491388 J. Cell Biol. 1999 PMC2156127 *Chimera|*Inclusion Bodies|*Cytosol|Golgi Apparatus|Dynactin Complex|Microtubules|Proteasome|Protein Transport|Molecular Chaperones|Ubiquitin|Organelles|Cytoplasm|Membrane Proteins|Cytoskeleton|Luminescent Proteins|Green Fluorescent Proteins|Protein Folding|Membrane Glycoproteins | |
10491434 J. Natl. Cancer Inst. 1999 *Cyclin-Dependent Kinase Inhibitor p16|Cyclin-Dependent Kinases|Cyclin-Dependent Kinase 4|Cell Cycle|*Mutations|Cyclins|Proto-Oncogene Proteins|Cyclin-Dependent Kinase 2|Cell Division|*Cyclin-Dependent Kinase Inhibitor Proteins|Cyclin-Dependent Kinase Inhibitor p27|Carrier Proteins|*Neoplasms|Microtubule-Associated Proteins|Amino Acid Sequence|Biological Products | |
10493790 Biochemistry 1999 Humans|FABP5 protein, human|*Fatty Acid-Binding Proteins|Fatty Acid-Binding Protein 7|Myelin P2 Protein|Nerve Tissue Proteins|Recombinant Proteins|Amino Acid Sequence|Fatty Acids|Ligands|Tumor Suppressor Proteins|Cloning, Molecular|cDNA|Calorimetry|Escherichia coli|Kinetics | |
10493836 Genomics 1999 Humans|Animals|Rats|*Membrane Transport Proteins|Base Sequence|cDNA|Sequence Alignment|Amino Acid Sequence|Cloning, Molecular|Intron|Chromosome Mapping|Exons|Carrier Proteins|Sequence Homology, Amino Acid|DNA|*Chromosome 3|DNA Primers|Open Reading Frame|RNA, Messenger|Genome, Human | |
10496324 J. Leukoc. Biol. 1999 Humans|PAK1 protein, human|*p21-Activated Kinases|*Pseudopodia|*Neutrophils|Formylmethionylleucylphenylalanine|Cytoskeleton|F-Actin|*Cell Membrane|Actin Cytoskeleton|cdc42 GTP-Binding Protein|rac GTP-Binding Proteins|Cell Polarity|Wortmannin|Cell Cycle Proteins|Chemoattractants|Signal Transduction|*Cell Surface Extensions|Phagocytosis | |
10496952 Mol. Pharmacol. 1999 Humans|*Mast Cells|5'-N-Ethylcarboxamidoadenosine|1-propylxanthine|Xanthines|2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine|Adenosine|N(6)-(3-iodobenzyl)-5'-N-methylcarboxamidoadenosine|Purinergic P1 Receptor Antagonists|enprofylline|Receptor, Adenosine A2B|Cyclic AMP|Anti-Asthmatic Agents|Binding, Competitive|Phenethylamines|ZM 241385|Triazoles|*Western Blotting|Triazines | |
10497202 J. Biol. Chem. 1999 Humans|Mice|Animals|*HIV-1|Receptors, CCR5|Amino Acid Sequence|*HIV Seropositivity|*Cytoplasm|CCR5 protein, human|CCR5 protein, mouse | |
10497257 J. Biol. Chem. 1999 *Cell Adhesion|Epidermal Growth Factor|Mitogen-Activated Protein Kinases|Signal Transduction Pathway|Phorbol Myristate Acetate|Heparin-binding EGF-like Growth Factor|raf-1 Kinase|*MAP Kinase Signaling System|Cell Line|Protein Kinase C|Phosphorylation|ADAM17 Protein|ADAM Proteins|Cell Membrane|*Epidermis|FN1 protein, human|Fibronectin|Heparin | |
10497264 Nucleic Acids Res. 1999 PMC148667 Humans|Gas Chromatography-Mass Spectrometry|*DNA Damage|DNA-Formamidopyrimidine Glycosylase|DNA Repair|oxoguanine glycosylase 1, human|DNA Glycosylases|Substrate Specificity|8-hydroxyguanine|Guanine|DNA|Escherichia coli Proteins|2,6-diamino-4-hydroxy-5-formamidopyrimidine|Pyrimidines|Escherichia coli|purine|Purines|Gamma Rays|Kinetics | |
10497269 Nucleic Acids Res. 1999 PMC148672 Humans|*Trans-Activators|*Receptors, Estrogen|*Promoter Regions, Genetic|*Binding Site|Transcription Factor AP-2|Transcription Factors|Transcription, Genetic|Activation, Transcriptional|Gene Expression Regulation, Neoplastic|Estrogens|Electrophoretic Mobility Shift Assay|PCR | |
10498338 Regul. Pept. 1999 Humans|Animals|Cattle|Rats|PRLH protein, human|*Prolactin-Releasing Hormone|*Tissue Distribution|receptor, prolactin-releasing peptide|Receptors, Neuropeptide|Hypothalamic Hormones|Neuropeptides|In Situ Hybridization|Gland, Pituitary|mRNA|Northern Blotting|Medulla Oblongata|Central Nervous System|Brain | |
10498607 Blood 1999 BTK protein, human|*Agammaglobulinaemia Tyrosine Kinase|*src Homology Domains|*Calcium Signaling|*Receptors, Antigen, B-Cell|Phospholipase C gamma|Tyrosine Kinase, SYK|B cell linker protein|*Adaptor Proteins, Signal Transducing|Phosphorylation|Protein-Tyrosine Kinases|*Protein Binding|B Cells|Calcium|src-Family Kinases|Intracellular Signaling Peptides and Proteins|Enzyme Activation|Isoenzymes | |
10498627 Blood 1999 *Receptors, Erythropoietin|Polycythemia, primary familial and congenital|*Polycythemia|EPO protein, human|*Erythropoietin|*Epoetin Alfa|JAK2 protein, human|Janus Kinase 2|*Heterozygote|STAT5A protein, human|STAT5 Transcription Factor|Erythroid Progenitor Cells|*Mutations|Signal Transduction|Trans-Activators|DNA-Binding Proteins|Phosphorylation|Tumor Suppressor Proteins | |
10498896 Oncogene 1999 Humans|CDK6 protein, human|Cyclin-Dependent Kinase 6|Cyclin-Dependent Kinase 4|Cyclin-Dependent Kinase Inhibitor p16|Melanoma|Germ-Line Mutation|Proto-Oncogene Proteins|Mutations|Protein Binding|Carrier Proteins|*Cyclin-Dependent Kinase Inhibitor Proteins | |
10499587 Nature 1999 Humans|Rats|Animals|urotensin II|*Urotensins|GPRC5C protein, human|Receptors, G-Protein-Coupled|*Vasoconstrictor Agents|Receptors, Cell Surface|Vasoconstriction|Binding Sites|Amino Acid Sequence|Endothelin-1|Cell Line|Arteries|Spinal Cords | |
10499802 Cell 1999 *Phosphorylation|CDK2 protein, human|Cyclin-Dependent Kinase 2|CCNE1 protein, human|Cyclin E|CDC2-CDC28 Kinases|Cyclin-Dependent Kinases|E2F Transcription Factors|Cyclins|Transcription Factors|Retinoblastoma Protein|Retinoblastoma-Binding Protein 1|Transcription Factor DP1|G1 Phase|Cyclin D|Cyclin-Dependent Kinase 4|Carrier Proteins|Proto-Oncogene Proteins | |
10499918 J. Exp. Med. 1999 PMC2195632 Female|Pregnancy|Humans|adhesion inhibitory receptor molecule 1|*Sialic Acid Binding Ig-like Lectin 1|*Receptors, Immunologic|*Natural Killer Cells|*Cloning, Molecular|TYRP1 protein, human|Membrane Glycoproteins|Amino Acid Sequence|Base Sequence|Antigens, CD|Chromosome Mapping|DNA, Complementary|Sequence Homology, Amino Acid | |
10500146 Proc. Natl. Acad. Sci. U.S.A. 1999 PMC18003 CDK5 protein, human|*Cyclin-Dependent Kinase 5|*Phosphorylation|cyclin-dependent kinase-activating kinase|CDK2 protein, human|Cyclin-Dependent Kinase 2|Neurons|Nerve Tissue Proteins|Cyclin|Protein Binding | |
10500157 Proc. Natl. Acad. Sci. U.S.A. 1999 PMC18014 Humans|CCND1 protein, human|*Cyclin D1|*Promoter Regions, Genetic|*Estrogens|Cyclic AMP Response Element-Binding Protein|estrogen receptor alpha, human|Estrogen Receptor alpha|Activating Transcription Factor 2|Proto-Oncogene Proteins c-jun|Response Elements|8-chloro-cyclic adenosine monophosphate|*8-Bromo Cyclic Adenosine Monophosphate|Transfection | |
10501970 Mamm. Genome 1999 Humans|Mice|Animals|*Caenorhabditis elegans|*Saccharomyces cerevisiae|coenzyme Q10|ubiquinone 7|*Ubiquinone|In Situ Hybridization, Fluorescence|Caenorhabditis elegans Proteins|Lifespan|*Yeast, Dried|Amino Acid Sequence|*Aging|Sequence Homology, Amino Acid|Genetic Complementation Test|Introns|Helminth Proteins|Mutations|Mitochondria|CLK-1 protein, C elegans | |
10503886 Cancer Lett. 1999 Humans|Rats|Animals|SULT1C2 protein, human|*Sulfotransferases|*Amines|Carcinogens|Cytosol|*Catalysis|Biotransformation|Amino Acid Sequence|Liver | |
10504389 Eur. J. Biochem. 1999 Humans|neolactotetraosylceramide alpha-2,3-sialyltransferase|N-acetyllactosaminide alpha-2,3-sialyltransferase|*Sialyltransferases|Escherichia coli|*Cloning, Molecular|Cytidine Monophosphate N-Acetylneuraminic Acid|asialofetuin|Fetuins|Asialoglycoproteins|Amino Acid Sequence|Base Sequence|Recombinant Proteins|cDNA|Binding Sites|Substrate Specificity|Liver | |
10504407 Eur. J. Biochem. 1999 Humans|Mice|Animals|*eIF-2 Kinase|Drosophila melanogaster|Eukaryotic Initiation Factor-2|Phosphorylation|Saccharomyces cerevisiae|Protein-Serine-Threonine Kinases|Saccharomyces cerevisiae Proteins|Protein Biosynthesis|Amino Acid Sequence|mRNA|Neurospora crassa|Endoplasmic Reticulum|cDNA|Sequence Homology, Amino Acid|*Mammals|Cloning, Molecular|GCN2 protein, Drosophila|Protein Kinases | |
10504731 Nat. Struct. Biol. 1999 *HIV-1|*Virus Internalization|*HIV Fusion Inhibitors|HIV Envelope Protein gp41|Anti-HIV Agents|Enfuvirtide|*HIV Antibodies|Membrane Fusion|Cell Fusion|Amino Acid Sequence|Peptide Fragments|Models, Molecular|Circular Dichroism|Ligands|Cell Line | |
10506123 J. Biol. Chem. 1999 Humans|Cricetinae|Animals|Ehlers-Danlos syndrome, progeroid form|xylosylprotein 4-beta-galactosyltransferase|*Ehlers-Danlos Syndrome|*Galactosyltransferases|*Mutations|Proteoglycans|Cloning, Molecular|Glycosaminoglycans|cDNA|CHO Cells|DNA|*Databases, Genetic | |
10506173 J. Biol. Chem. 1999 Animals|Mice|Humans|*DNA, Complementary|lysophosphatidic acid phosphatase|*Phosphoric Monoester Hydrolases|Amino Acid Sequence|Blotting, Northern|Cloning, Molecular|Base Sequence|Sequence Homology, Amino Acid|*Organelle Biogenesis|*Mitochondria|*Lipogenesis|Transfections|*Lipids | |
10507370 Vet. Immunol. Immunopathol. 1999 Animals|*Chickens|MBL2 protein, human|*Mannose-Binding Lectin|Herpesvirus 1, Gallid|Infectious bronchitis virus|Poultry Diseases|*Virus Infections|Collectin|*Acute-Phase Proteins|Lectins|Antibodies, Viral|Carrier Proteins|Mannans | |
10508167 EMBO J. 1999 PMC1171604 *Active Transport, Cell Nucleus|*Mitogen-Activated Protein Kinases|Map Kinase Kinase|Cytoplasm|Cell Nucleus|Phosphorylation|MAPK1 protein, human|Mitogen-Activated Protein Kinase 1|Schizosaccharomyces pombe Proteins|Cytosol|Nuclear Pore|Signal Transduction|MAP Kinase Signaling System | |
10508235 Physiol. Rev. 1999 Humans|Receptors, Platelet Derived Growth Factor|Tumors|Simian Sarcoma Virus|Platelet Derived Growth Factor B|Protein-Tyrosine Kinases|Phosphorylation|Cell Proliferation|Fibrosis | |
10508780 Structure 1999 Humans|hydroxyacylglutathione hydrolase|*Thiolester Hydrolases|Kinetics|Models, Molecular|Binding Sites|Substrate Specificity|Catalysis|Glutathione|Amino Acid Sequence|Sequence Homology, Amino Acid|Zinc|Hydrolysis | |
10510269 Braz. J. Med. Biol. Res. 1999 Animals|Child|Humans|Aquaporins|AQP3 Protein|*Colon|Northern Blots|Intestine, Small|mRNA|Jejunum|Biological Transport|Amino Acid Sequence|Gastrointestinal Tract|Duodenum|Xenopus laevis|Stomach|Cell Membrane|Immunocytochemistry|Osmosis|AQP3 protein, human | |
10510379 J. Immunol. 1999 Humans|*NF-kappa B|*Interleukin-4|STAT6 protein, human|*STAT6 Transcription Factor|Transcription Factor|Trans-Activators|Promoter Regions, Genetic|Gene Expression Regulation|Binding Site|Transcription, Genetic|*Germ Line|DNA-Binding Proteins|Transcriptional Activation|B-Lymphocytes|Signal Transduction|Reporter Gene|Immunoglobulin E | |
10510450 Br. J. Pharmacol. 1999 PMC1571647 Animals|Mice|Humans|ectoATPase|*DNA, Complementary|*Adenosine Triphosphatases|Apyrase|Amino Acid Sequence|Base Sequence|Cloning, Molecular|Substrate Specificity|Nucleotides|Antigens, CD|DNA|Sequence Homology, Amino Acid|Hydrolysis|Splicings, Alternative | |
10512639 Biochemistry 1999 Humans|mycothione reductase|*Mycobacterium tuberculosis|*Oxidoreductases|thionicotinamide adenine dinucleotide phosphate|NADPH|trypanothione reductase|NADH, NADPH Oxidoreductases|Redox|Kinetics|Flavin-Adenine Dinucleotide|NAD|Amino Acid Sequence|Disulfides|Catalysis | |
10512690 Growth Horm. IGF Res. 1999 CTSG protein, human|*Cathepsin G|*Elastase|*Neutrophils|*Proteolytic Enzymes|*IGFBP|IGFBP3 protein, human|Insulin-Like Growth Factor Binding Protein 3|IGFBP5 protein, human|Insulin-Like Growth Factor Binding Protein 5|Insulin-Like Growth Factor Binding Protein 4|IGF1 protein, human|IGF-1|Insulin-Like Growth Factor Binding Protein 2|tripeptide aminopeptidase|*Aminopeptidases|Insulin-Like Growth Factor II|endopeptidase B | |
10512730 Biochem. Biophys. Res. Commun. 1999 Humans|alcohol sulfotransferase|Sulfotransferases|estrone sulfotransferase|Arylsulfotransferase|*Liver|Sulfates|Cytosol|Nitrophenols|Kinetics|Triiodothyronine|Substrate Specificity | |
10512739 Biochem. Biophys. Res. Commun. 1999 sapropterin|*Peroxynitrous Acid|7,8-dihydrobiopterin|*Biopterin|*Oxidation-Reduction|Nitric Oxide Synthase|Nitric Oxide Synthase Type III|Superoxide Anion|Nitric Oxide|Oxidative Stress|Endothelium, Vascular | |
10513892 Biosci. Rep. 1999 Humans|Animals|Cats|Cattle|Mice|*alpha-Mannosidase|*Mannosidases|alpha-Mannosidosis|*Lysosomes|Mannose|Oligosaccharides|Glycoproteins|Liver|Mutations|Substrate Specificity|Disease Models, Animal|Cloning, Molecular | |
10514377 Science 1999 *Ligase, Ubiquitin-Protein|UBE2D2 protein, human|*Ubiquitin-Conjugating Enzymes|*Tyrosine Kinase|c-cbl Protein|src Homology Domain|Receptor Protein-Tyrosine Kinases|Phosphorylation|Proto-Oncogene Proteins|Ubiquitins|Phosphotyrosine|ErbB Receptors|Signal Transduction|Ubiquitin|Adaptor Proteins, Signal Transducing | |
10514424 J. Biol. Chem. 1999 Animals|I kappa B beta protein|*beta-Transducin Repeat-Containing Proteins|*I-kappa B Proteins|NFKBIA protein, human|IKappaBalpha|*Ubiquitination|NF-kappa B|Ubiquitins|DNA-Binding Proteins|Phosphorylation|Cullin Proteins|Cell Cycle Proteins|Ubiquitin-Protein Ligases|SKP Cullin F-Box Protein Ligases|GTP-Binding Proteins|Signal Transduction | |
10514433 J. Biol. Chem. 1999 Mice|Animals|NFKBIA protein, human|*NF-KappaB Inhibitor alpha|*Ubiquitin|*Proteolysis|Cullin 1|Cullin Proteins|beta TrCP|I-kappa B Proteins|Ubiquitins|DNA-Binding Proteins|Cell Cycle Proteins|SKP Cullin F-Box Protein Ligases|Phosphorylation|Ubiquitin-Protein Ligases|NF-kappa B|GTP-Binding Proteins|S-Phase Kinase-Associated Proteins|Amino Acid Sequence | |
10514445 J. Biol. Chem. 1999 Animals|Humans|*Methionine Adenosyltransferase|Cloning, Molecular|S-Adenosylmethionine|*Catalysis|Kinetics|Amino Acid Sequence|cDNA|Isoenzymes|Transfections | |
10514455 J. Biol. Chem. 1999 Rats|Animals|FABP1 protein, human|Liver Fatty Acid-Binding Protein|Phosphatidic Acid|Palmitoyl CoA|Fatty Acid-Binding Protein 7|Glycerol-3-Phosphate O-Acyltransferase|*Mitochondria|lysophosphatidic acid|Lysophospholipids|alpha-glycerophosphoric acid|Glycerophosphates|Mitochondria, Liver|Nerve Tissue Proteins|Acylation|Microsomes, Liver|Neoplasm Proteins|*Lipogenesis|Liver | |
10514471 J. Biol. Chem. 1999 Humans|Mice|Animals|*Antioxidants|HeLa Cells|Peroxisomes|Peroxisome-Targeting Signal 1 Receptor|Peroxisomal Targeting Signal 2 Receptor|Amino Acid Sequence|Membrane Protein|Saccharomyces cerevisiae Proteins|Saccharomyces cerevisiae|Intracellular Membranes|Receptors, Cytoplasmic and Nuclear|Protein Transport|Sequence Homology, Amino Acid|Cloning, Molecular|Mutagenesis|Catalase|Acetyl-CoA C-Acetyltransferase | |
10514492 J. Biol. Chem. 1999 Humans|Cricetinae|Animals|*Leptin|Cricetulus|cytokine inducible SH2-containing protein|*Suppressor of Cytokine Signaling Proteins|SOCS2 protein, human|*Signal Transduction|leptin receptor, human|Receptors, Leptin|DNA-Binding Proteins|Trans-Activators|JAK2 protein, human|Janus Kinase 2|Repressor Proteins|Suppressor of Cytokine Signaling 3 Protein|Immediate-Early Proteins|Phosphorylation|Suppressor of Cytokine Signaling 1 Protein|STAT5 Transcription Factor | |
10515893 Blood 1999 Humans|Female|GCLC protein, human|*Glutamate-Cysteine Ligase|Base Sequence|Amino Acid Sequence|Homozygote|cDNA|Haemolytic Anaemia|DNA|Subunit, Catalytic|Heterozygote|*Amino Acid Metabolism, Inborn Errors|*Databases, Genetic | |
10516278 Am. J. Physiol. 1999 Humans|*Parathyroid Hormone|HEK293 Cells|Sodium-Phosphate Cotransporter Proteins|Sodium-Phosphate Cotransporter Proteins, Type II|*Kidney|Biological Transport|Sodium-Phosphate Cotransporter Proteins, Type III|Symporters|Sodium-Phosphate Cotransporter Proteins, Type I|Phosphate|Sodium|Forskolin|Phorbol Myristate Acetate|Staurosporine|mRNA|PTHLH protein, human|Parathyroid Hormone-Related Protein | |
10517632 Nature 1999 Animals|*Kinase I, Casein|CTNNB1 protein, human|beta Catenin|Wnt Proteins|Trans-Activators|Phosphorylation|Phosphoproteins|Adaptor Proteins, Signal Transducing|Signal Transduction|Dishevelled Proteins|Protein Kinases|Casein Kinases|Xenopus Proteins|Axin Protein|Zebrafish Proteins|Proto-Oncogene Proteins|Xenopus laevis|Repressor Proteins | |
10518023 FEBS Lett. 1999 Humans|*Pentose Phosphate Pathway|6-phosphogluconolactonase|*DNA, Complementary|Carboxylic Ester Hydrolases|Glucosephosphate Dehydrogenase|Escherichia coli|galactose-6-phosphate dehydrogenase|Carbohydrate Dehydrogenases|glucosamine-6-phosphate isomerase|Aldose-Ketose Isomerases|Amino Acid Sequence|Bacterial Gene|*Catalysis|Kinetics | |
10518211 Mol. Cell 1999 *Fatty Acid-Transport Protein|Carrier Proteins|Enterocytes|Membrane Transport Proteins|Intestine, Small|Biological Transport|Membrane Proteins|*Intestines|RNA, Messenger | |
10518217 Mol. Cell 1999 *Tumor Suppressor Protein p53|EP300 protein, human|*E1A-Associated p300 Protein|Trans-Activators|Transcription Factors|Nuclear Proteins|Proto-Oncogene Proteins c-mdm2|Gene Expression Regulation|DNA-Binding Proteins|Transcription, Genetic|Transcriptional Activation|p300-CBP Protein|Protein Binding|Protein Isoforms|Apoptosis | |
10518787 Eur. J. Biochem. 1999 Humans|*DNA Polymerase I|HeLa Cells|CDC45 protein, human|*Cell Cycle Proteins|*DNA Replication|MCM7 protein, human|*Minichromosome Maintenance Complex Component 7|Saccharomyces cerevisiae Proteins|Saccharomyces cerevisiae|Nuclear Proteins|DNA-Binding Proteins|Carrier Proteins|DNA, Fungal|G1 Phase | |
10518789 Eur. J. Biochem. 1999 Humans|Mice|Animals|*Adrenodoxin|*Ferredoxin-NADP Reductase|*Calcifediol|*Escherichia coli|*NADP|Kinetics|25-Hydroxyvitamin D3 1-alpha-Hydroxylase|Rickets|Vitamin D3 24-Hydroxylase|Cloning, Molecular|Substrate Specificity|cDNA|Mixed Function Oxygenases | |
10519157 Proc. Assoc. Am. Physicians 1999 Humans|*Peroxidase|Hydrogen Peroxide|Respiratory Burst|Phagocytosis|Neutrophils|Chronic Granulomatous Disease|Superoxide Anion|Oxidants|Hypochlorous Acid|Phagosome|Oxidation-Reduction|Monocytes|Oxygen Consumption|Chloramines|Oxygen|Cytoplasmic Granules|Myeloperoxidase Deficiency|Metabolism, Inborn Errors | |
10519551 Nature 1999 *Transforming Growth Factor beta|Receptors, Transforming Growth Factor beta|Bone Morphogenetic Proteins|*Signal Transduction|Activins|Protein-Serine-Threonine Kinases|BAMBI protein, human|*Membrane Proteins|Inhibins|Receptor, Transforming Growth Factor-beta Type I|Amino Acid Sequence|Cell Differentiation|Growth Factors|Cell Line|Sequence Homology, Amino Acid | |
10520994 Cell 1999 Animals|Chlorocebus aethiops|*Neuropilin-1|plexin|*Semaphorin-3A|Nerve Tissue Proteins|Cell Adhesion Molecules|Growth Cone|Axons|Semaphorin-3|Binding Proteins|Receptors, Cell Surface|Ganglia, Spinal|Neurons, Afferent|Signal Transduction|COS Cells | |
10520995 Cell 1999 Humans|Animals|plexin|CD100 antigen|*Semaphorins|*Nerve Tissue Proteins|*Cell Adhesion Molecules|Antigens, CD|*Carrier Proteins|Receptors, Cell Surface|Sema3A|Signal Transduction Pathway|Axons|semaphorin K1|Membrane Proteins|Neuropilin-1|Neurons|*Vertebrates|Protein Binding|Ligands | |
10521251 Biochemistry 1999 *Insulin|Kinetics|Ferric Compounds|*Insulin, Regular, Human|*Ions|Ligands|Protein Conformation|Zinc|Allosteric Site|Allosteric Regulation|Models, Molecular|Magnetic Resonance Spectroscopy|Cobalt|*Metals|Phenols|Phenol | |
10521295 Am. J. Hum. Genet. 1999 PMC1288282 Humans|Infant, Newborn|Child, Preschool|Child|Young Adult|Adult|Middle Aged|*Galactosemias|*Roma|Galactokinase|Mutation|Mutation, Missense|Amino Acid Sequence|Chromosome Mapping|Cataracts|Haplotype|Europe|Bulgaria | |
10521347 Science 1999 Humans|*beta-Defensins|*T Cells|Macrophage Inflammatory Proteins|Receptors, CCR6|Chemokine CCL20|Chemokines, CC|Chemotaxis|Immunologic Memory|*Adaptive Immunity|Pertussis Toxin|CCR6 protein, human | |
10521396 Genes Dev. 1999 PMC317073 CASP8 protein, human|*Caspase 8|*Death Domain|FADD protein, human|Fas-Associated Death Domain Protein|*Apoptosis|Caspase 9|Caspases|Receptor-Interacting Protein Serine-Threonine Kinases|TNF-Related Apoptosis-Inducing Ligand|Apoptosis Regulatory Proteins|Receptors, TNF-Related Apoptosis-Inducing Ligand|Signal Transduction|fas Receptor|NF-kappa B|TNF Receptor-Associated Death Domain Protein|TNF Receptor-Associated Factor 1|Tumor Necrosis Factor-alpha | |
10521424 J. Biol. Chem. 1999 Humans|Animals|Rats|*Peroxiredoxin|*Antioxidants|Escherichia coli|Amino Acid Sequence|Cloning, Molecular|Recombinant Proteins|Base Sequence|Thioredoxins|Sequence Homology, Amino Acid|Oxidation-Reduction|cDNA|*Mammals|Saccharomyces cerevisiae|Hydrogen Peroxide | |
10521434 J. Biol. Chem. 1999 Humans|Rats|Animals|*NADP|isocitrate dehydrogenase (NADP+)|*Isocitrate Dehydrogenase|Kinetics|*Cytosol|*Cytoplasm|Peroxisomes|Amino Acid Sequence|Saccharomyces cerevisiae|Genes, Fungal|Microbodies|Cloning, Molecular|Mitochondria|Oxidation-Reduction|Fatty Acids|Sequence Homology, Amino Acid|Shunt, Hexose Monophosphate|New York | |
10521483 J. Biol. Chem. 1999 *Cell Survival|GRB14 protein, human|GRB2 protein, human|GRB2 Adaptor Protein|PTPN11 protein, human|Protein Tyrosine Phosphatase, Non-Receptor Type 11|SH2 Domains|Binding Sites|SH2 Domain-Containing Protein Tyrosine Phosphatases|Signal Transduction Pathways|Protein Binding|Phosphotyrosine|Phosphoproteins|Phosphorylation|Amino Acid Sequence|Receptor Protein-Tyrosine Kinases|Protein Tyrosine Phosphatase, Non-Receptor Type 6|TIE-2 Receptor Tyrosine Kinase | |
10521578 Brain Res. Mol. Brain Res. 1999 Humans|Mice|Animals|*Cryptochromes|Suprachiasmatic Nucleus|Photoreceptor Cells, Invertebrate|Period Circadian Proteins|Eye Proteins|Biological Clocks|Circadian Rhythm|Transcription Factors|Drosophila Proteins|Nuclear Proteins|Cell Cycle Proteins|Gene Expression Regulation|Genes, Regulator|Receptors, G-Protein-Coupled|RNA, Messenger|Mutation | |
10521801 Int. J. Cancer 1999 Humans|HGF protein, human|*Hepatocyte Growth Factor|*Phosphorylation|*Integrins|PTK2 protein, human|Focal Adhesion Kinase 1|Focal Adhesion Kinase|MET protein, human|Proto-Oncogene Proteins c-met|Cell Adhesion|FN1 protein, human|Fibronectin|Focal Adhesions|Cell Movement|Signal Transduction|laminin 1|Laminin|Extracellular Matrix Proteins | |
10523313 EMBO J. 1999 PMC1171637 Humans|Animals|HeLa Cells|DBF4 protein, human|*Cell Cycle Proteins|CDC7 protein, human|*Protein-Serine-Threonine Kinases|*DNA Replication|MCM2 protein, human|Minichromosome Maintenance Complex Component 2|Phosphorylation|Saccharomyces cerevisiae|Saccharomyces cerevisiae Proteins|Nuclear Proteins|DNA-Binding Proteins|Cell Cycle|Cell Division|Protein Binding|CDC7 protein, S cerevisiae | |
10523666 Mol. Cell. Biol. 1999 PMC84835 Mice|Rats|Animals|AKT1 protein, human|AKT2 protein, human|*Protein Kinase B beta|B-insulin|*Insulin|*Adipocytes|*Insulin, Regular, Human|3T3-L1|Phosphatidylinositol 3-Kinases|Phosphorylation|Biological Transport|Glucose|Proto-Oncogene Proteins|Monosaccharide Transport Proteins|Muscle Proteins|Signal Transduction|Platelet-Derived Growth Factor|Plasma Membrane | |
10523831 Oncogene 1999 Swine|Animals|*Phosphorylation|*src-Family Kinases|*Proto-Oncogene Proteins c-kit|*Mitogen-Activated Protein Kinases|GRB2 protein, human|GRB2 Adaptor Protein|*Signal Transduction|MAPK1 protein, human|Mitogen-Activated Protein Kinase 1|Shc Signaling Adaptor Proteins|MAP Kinase Signaling System|Adaptor Proteins, Vesicular Transport|Src Homology 2 Domain-Containing, Transforming Protein 1|*Proto-Oncogene Proteins c-fos|Tyrosine|Protein Binding|ras Proteins | |
10523834 Oncogene 1999 Humans|Mice|Animals|*NIH 3T3 Cells|Mice, Nude|*Proto-Oncogene Proteins c-kit|*Signal Transduction|Steel Factor|*Isoforms|Phosphorylation|Phosphatidylinositol 3-Kinases|Cell Transformation, Neoplastic|*Fibroblasts|Mitogen-Activated Protein Kinases|Protein Binding|Alternate Splicing|Contact Inhibition|Ligands | |
10524214 Biochim. Biophys. Acta 1999 Humans|*Hydroxypyruvate Reductase|*DNA, Complementary|glyoxylate reductase|Alcohol Oxidoreductases|glyoxylic acid|*Glyoxylates|Hyperoxaluria, Primary|Base Sequence|Amino Acid Sequence|Mutation|Liver | |
10524633 Nature 1999 Humans|*DNA Damage|G2 Phase|Cyclin B1|Mitosis|CDC2 Protein Kinase|Cell Cycle|cdc25 Phosphatases|Tumor Suppressor Protein p53|Cell Nucleus|Phosphorylation|*Cell Death | |
10525529 J. Cell Biol. 1999 PMC2174216 Male|Mice|Animals|*Synaptinemal Complex|Meiosis|Cell Cycle Proteins|Rad51 Recombinase|Spermatocytes|DNA-Binding Proteins|Saccharomyces cerevisiae|Nuclear Proteins|Saccharomyces cerevisiae Proteins|Adenosine Triphosphatases|Cell Nucleus|Homologous Recombination|RAD51 protein, S cerevisiae|DMC1 protein, S cerevisiae | |
10526214 Mutat. Res. 1999 Humans|Animals|*Nucleotide Excision Repair|Xeroderma Pigmentosum Group A Protein|DNA Damage|Transcription Factor TFIIH|Xeroderma Pigmentosum|Transcription Factors|TYRP1 protein, human|*Membrane Glycoproteins|Saccharomyces cerevisiae|Protein Binding | |
10526235 Genes Cells 1999 RNA Caps|RNA Replicase|RNA Polymerase|Viral Proteins|Orthomyxoviridae|RNA, Viral|mRNA|Endonucleases|Amino Acid Sequence|Catalytic Domain | |
1052766 Ann. Hum. Genet. 1975 Humans|Pregnancy|Female|*Aconitase|*Polymorphism, Genetic|Alleles|Isozymes|Chromosome Mapping|Phenotypes|Mitochondria|Placenta | |
10529219 Biochemistry 1999 Adult|Humans|*Histidine|*2,3-Diphosphoglycerate|*Oxyhemoglobins|*Hemoglobin|Hemoglobin A|Mutagenesis, Site-Directed|Hydrogen-Ion Concentration|Proton|Nuclear Magnetic Resonance, Biomolecular|Amino Acid Substitution|Magnetic Resonance Spectroscopy|Protein Conformation|Binding Site|Oxygen | |
10529426 Development 1999 Animals|*Drosophila|Hedgehog Proteins|Transcription Factor|Drosophila Proteins|DNA-Binding Proteins|Drosophila melanogaster|Signal Transduction|Protein-Serine-Threonine Kinases|Cyclic AMP-Dependent Protein Kinases|Repressor Proteins|Cell Nucleus|Gene Expression Regulation, Developmental|Phosphorylation|Kinesin|Cytoplasm | |
10531003 Curr. Biol. 1999 Humans|*Coiled Bodies|*Nuclear Ribonucleoproteins, Small|*Cell Nucleus|Cell Nucleolus|Small Nuclear Ribonucleoprotein B|SMN Complex Proteins|Cytoplasm|Small Nuclear RNA|Nuclear Import|Luminescent Proteins|RNA Splicing|Nuclear Proteins|Green Fluorescent Proteins|HeLa Cells|Autoantigens | |
10531061 Science 1999 Animals|*Circadian Clocks|Cryptochrome|ARNTL Transcription Factors|CLOCK Proteins|Period Circadian Proteins|Suprachiasmatic Nucleus|Nuclear Proteins|Photoreceptor Cells, Invertebrate|Trans-Activators|Circadian Rhythm|Cell Cycle Proteins|Drosophila Proteins|Eye Proteins|Drosophila|*Mammals|Receptors, G-Protein-Coupled | |
10531062 Science 1999 *Transforming Growth Factor beta|SMAD3 protein, human|Smad3 Protein|SMAD2 protein, human|Smad2 Protein|SKIL protein, human|*Proto-Oncogene Proteins|*Intracellular Signaling Peptides and Proteins|SMAD4 protein, human|Smad4 Protein|*Signal Transduction|Trans-Activators|Transcription, Genetic|Smad Proteins|Ligands | |
10531307 J. Biol. Chem. 1999 *C5 Convertase|*Catalytic Domain|*Receptors, Complement|Receptors, Complement 3b|Complement C3b|CD55 Antigens|Complement Activation|Binding Sites|Mutagenesis, Site-Directed | |
10531310 J. Biol. Chem. 1999 Humans|Mice|Animals|IRS4 protein, human|*Insulin Receptor Substrate Proteins|IGF1 protein, human|*Insulin-Like Growth Factor I|CRKL protein|GRB2 protein, human|GRB2 Adaptor Protein|Insulin Like Growth Factor I Receptor|Phosphoproteins|Signal Transduction|Cell Division|src Homology Domains|Shc Signaling Adaptor Proteins|Phosphorylation|*Cell Proliferation|Adaptor Proteins, Vesicular Transport|Nuclear Proteins | |
10531334 J. Biol. Chem. 1999 Humans|Animals|Mice|6-pyruvoyltetrahydropterin synthase|*Phosphorylation|*Serine|Phosphorus-Oxygen Lyases|PRKG2 protein, human|*Cyclic GMP-Dependent Protein Kinase Type II|*Cyclic GMP|PRKG1 protein, human|Cyclic GMP-Dependent Protein Kinase Type I|Amino Acid Sequence|*Nitric Oxide Synthase|Protein Conformation|Binding Sites|Transfections|Mutagenesis, Site-Directed|Cell Line|Kinetics|sapropterin | |
10531362 J. Biol. Chem. 1999 Animals|*Polyomavirus Enhancer Binding Protein 2|SMAD3 protein, human|Smad3 Protein|Transforming Growth Factor beta|*Promoter Regions, Genetic|Bone Morphogenetic Protein|Receptors, Transforming Growth Factor beta|Trans-Activators|Protein-Serine-Threonine Kinases|Smad2 Protein|Transductions, Signal|Transcription, Genetic|Smad, Common|Nuclear Proteins|Activin Receptors, Type I|Receptor, Transforming Growth Factor-beta Type I|Protein Binding|Binding Sites | |
10531386 J. Biol. Chem. 1999 *Receptor for Advanced Glycation End Products|N(6)-carboxymethyllysine|*Ligands|*Lysine|Glycation End Products, Advanced|*Signal Transduction|Receptors, Immunologic|Diabetes Mellitus|NF-kappa B|Endothelium, Vascular|Cells, Cultured|*Gene Expression|Atherosclerosis|Inflammation | |
10533284 Int. J. Biochem. Cell Biol. 1999 Humans|DNA Binding Protein|Core Binding Factor Alpha 2 Subunit|Gene Activation|Promoter Regions, Genetic|*Leukemia|Binding Site|Proto-Oncogene Proteins|Neoplasm Proteins|*Receptors, Complement|Translocation, Genetic|Protein Binding|*Chromosome Aberrations|CR1 protein, human|Receptors, Complement 3b | |
10533983 J. Recept. Signal Transduct. Res. 1999 tropomyosin-related kinase-B, human|*Receptor, trkB|*Phospholipase C gamma|*Signal Transduction Pathways|BDNF protein, human|Brain-Derived Neurotrophic Factor|neurotrophin 4|*Membrane Glycoproteins|Phosphorylation|Receptors, Nerve Growth Factor|*Cellular Proliferation|Receptor Protein-Tyrosine Kinases|Mitogen-Activated Protein Kinases|Calcium-Calmodulin-Dependent Protein Kinases|Adaptor Proteins, Vesicular Transport|Tyrosine|Shc Signaling Adaptor Proteins | |
10535736 Cell 1999 Mice|Animals|*Synaptic Vesicles|phosphoinositide 5-phosphatase|Phosphoric Monoester Hydrolases|polyphosphoinositide phosphatase|Clathrin-Coated Vesicles|synaptojanin|Nerve Tissue Proteins|Clathrin|Endocytosis|Synaptic Transmission|Neurons|Synapses|Nerve Endings|Adaptor Proteins, Signal Transducing|Phosphoinositides | |
10535940 Proc. Natl. Acad. Sci. U.S.A. 1999 PMC22941 Humans|VHL protein, human|*Von Hippel-Lindau Tumor Suppressor Protein|ELOC protein, human|Elongin C|Cullin 1|Cullin Proteins|TPX2 protein, human|Cell Cycle Proteins|RBX1 protein, human|Carrier Proteins|Ligases|Nuclear Proteins|von Hippel-Lindau Disease|Carcinoma, Renal Cell|Skp1 Cullin 1 F box Ubiquitin Ligase|Ubiquitin|Transcription Factors|Genes, Tumor Suppressor | |
10535941 Proc. Natl. Acad. Sci. U.S.A. 1999 PMC22943 *Transforming Growth Factor beta|SMAD3 protein, human|Smad3 Protein|SKIL protein, human|*Proto-Oncogene Proteins|*Intracellular Signaling Peptides and Proteins|*Signal Transduction|Trans-Activators|Smad2 Protein|Protein Binding|Cell Nucleus|Transcription, Genetic|Activation, Transcriptional|Gene Expression Regulation|Nuclear Protein|Cell Division | |
10535959 Proc. Natl. Acad. Sci. U.S.A. 1999 PMC22983 Animals|CTNNB1 protein, human|*beta Catenin|*Casein Kinase Iepsilon|*Wnt Signaling Pathway|Wnt Proteins|Dishevelled Proteins|Axin Protein|Protein Kinases|Casein Kinases|Phosphoproteins|Adaptor Proteins, Signal Transducing|Trans-Activators|Zebrafish Proteins|Xenopus Proteins|Phosphorylation|Proto-Oncogene Proteins|Repressor Proteins|Xenopus laevis | |
10535998 Proc. Natl. Acad. Sci. U.S.A. 1999 PMC23093 Humans|Rats|Animals|*Venules|Endothelial Cells|sodium-dependent dicarboxylate transporter 2, rat|Organic Anion Transporters, Sodium-Dependent|Symporters|Slc13a4 protein, rat|*Transporters, Sulphate|SLC26A2 protein, human|*Cloning, Molecular|Dicarboxylic Acid Transporters|Biological Transport|DNA, Complementary|Amino Acid Sequence|Anion Exchanger 4|Sodium|Blotting, Northern|Membrane Proteins|Xenopus laevis | |
10536037 Glycobiology 1999 Humans|*Sialyltransferases|*Acetylgalactosamine|sialosyl-Tn antigen|*Antigens, Tumor-Associated, Carbohydrate|Carbohydrate Sequence|Amino Acid Sequence|Complementary DNA|Polymerase Chain Reaction|Cloning, Molecular|DNA Primers|Substrate Specificity|Prognosis|Gastric Cancer|Colorectal Cancer | |
10536140 Nucleic Acids Res. 1999 PMC148714 Humans|*Polymorphism, Single Nucleotide|Exon|DNA Repair Enzymes|Phosphoric Monoester Hydrolases|mRNA|*Polypeptides|*Protein Processing, Post-Translational | |
10536157 Nucleic Acids Res. 1999 PMC148731 Humans|*DCMP|*DNA-Directed DNA Polymerase|REV1 protein, human|Saccharomyces cerevisiae|Saccharomyces cerevisiae Proteins|*DNA Replication|DNA Damage|DNA Repair|Mutagenesis|DCMP protocol|*Antineoplastic Combined Chemotherapy Protocols|*Cytarabine|DNA|*Daunorubicin|Nuclear Proteins|*Mercaptopurine|Base Sequence|*Prednisolone | |
10536878 J. Enzym. Inhib. 1999 Humans|Animals|Rats|Swine|*Enalaprilat|*Captopril|ramiprilat|*Peptidyl-Dipeptidase A|*Ramipril|Angiotensin-Converting Enzyme Inhibitors|Kinetics|*Lung|phenylalanyl-glycyl-glycine|Oligopeptides|hippuryl-histidyl-leucine|*Inhibition, Psychological|Chlorides | |
10540230 Immunology 1999 PMC2326920 invariant chain|*Antigens, Differentiation, B-Lymphocyte|*Class II Antigens|*B-Lymphocytes|*Cell Lines|Lymphoma, B-Cell|Antibodies|Tumor Cells, Cultured|Cell Membrane | |
10542048 Eur. J. Biochem. 1999 Humans|*Metallothionein|Cadmium|Protein Conformation|*Chelating Agents|Amino Acid Sequence|Circular Dichroism|Protein Binding|Metals|Binding Sites|Models, Molecular|Spectrophotometry, Ultraviolet|Cysteine | |
10542231 J. Biol. Chem. 1999 Humans|*src Homology Domains|amphiphysin|synaptojanin|*Nerve Tissue Proteins|phosphoinositide 5-phosphatase|*Phosphoric Monoester Hydrolases|Carrier Proteins|Amino Acid Sequence|Adaptor Proteins, Signal Transducing|Binding Site|Protein Binding|Peptide Libraries|Proline | |
10542244 J. Biol. Chem. 1999 Humans|*Transcriptional Activation|*Genes, bcl-2|*Estradiol|Receptors, Estrogen|ERalpha|Promoter Regions, Genetic|Sp1 Transcription Factor|Transfection|Gene Expression Regulation, Neoplastic|Gene Expression|Tumor Cells, Cultured|DNA | |
10542297 J. Biol. Chem. 1999 Animals|*Phosphorylation|*Interferon-beta|*Receptor, Interferon alpha-beta|STAT3 protein, human|*STAT3 Transcription Factor|STAT1 protein, human|STAT1 Transcription Factor|STAT2 Transcription Factor|TYK2 Kinase|Janus Kinase 1|Signal Transduction|Interferon-Stimulated Gene Factor 3|Interferon-Stimulated Gene Factor 3, gamma Subunit|Receptors, Interferon|Trans-Activators|Interferon-alpha|Membrane Proteins|Tyrosine | |
10542332 Biochim. Biophys. Acta 1999 Humans|GABA-C receptor|*Radiation Hybrid Mapping|*Receptors, GABA|*Genetic Linkage|GABA A Receptor|Receptors, GABA-B|Genetic Predisposition to Disease|Genotype|Polymorphism, Single Nucleotide|GABRR2 protein, human | |
10542397 Trends Endocrinol. Metab. 1999 *Receptors, Nuclear|*Receptors, Steroid|Nuclear Proteins|*Steroids|Transcriptional Activation|Gene Expression Regulation|Chromatin Assembly and Disassembly|*Cell Nucleus|Ligands | |
10543983 Biochem. Biophys. Res. Commun. 1999 Integrin alphaXbeta2|*CD11c Antigen|beta2 Integrin|Protein Binding|Macrophage-1 Antigen|Ligands|Binding Sites|Integrins|Fibrinogen|Leukocytes|Amino Acids|Alanine | |
10544125 Virology 1999 Humans|Animals|*HIV-1|nef protein, Human immunodeficiency virus 1|nef Gene Products, Human Immunodeficiency Virus|*Virus Replication|Simian Immunodeficiency Virus|lck Kinase|Jurkat Cells|src Kinases|SH2 Domains|Amino Acid Sequence|Lymphocyte Activation|Phosphorylation|nef protein, Human immunodeficiency virus 2 | |
10544250 FEBS Lett. 1999 Humans|Mice|Animals|nidogen|fibulin|*Tropoelastin|microfibrillar protein|*Extracellular Matrix Proteins|fibulin 2|Membrane Glycoproteins|*Calcium-Binding Proteins|perlecan|Heparan Sulfate Proteoglycans|NID2 protein, human|*Cell Adhesion Molecules|laminin 1|Laminin|FN1 protein, human|Fibronectin|Heparitin Sulfate|Extracellular Matrix | |
10545110 EMBO J. 1999 PMC1171664 Animals|*Drosophila|Drosophila Proteins|*Protein Transport|*Carrier Proteins|Endoplasmic Reticulum|Membrane Protein|Genes, Insect|Receptors, Notch|Thapsigargin|Sarcoplasmic Reticulum Calcium-Transporting ATPases|Mutations|Cell Membrane|biphenyl-2-carboxylic acid|*Biphenyl Compounds|*Benzoates|Alleles|notch protein, Drosophila | |
10545116 EMBO J. 1999 PMC1171670 Mice|Animals|*Receptor, Nerve Growth Factor|NGFR protein, human|Receptors, Nerve Growth Factor|*Programmed Cell Death|*Zinc Finger|Nerve Tissue Proteins|Intracellular Signaling Peptides and Proteins|Protein Binding|Nerve Growth Factor|DNA-Binding Proteins|Binding Protein|Signal Transduction|Neurons|Mice, Transgenic|Cell Death|Protein Transport|Cells, Cultured | |
10548110 Nature 1999 Animals|*Anaphase Promoting Complex|*Cyclin|*Cyclin B1|*Anaphase|S Phase|Cell Cycle|Cell Cycle Proteins|*Proliferating Cell Nuclear Antigen|Cyclin A|Cyclin-Dependent Kinases|CDK2 protein, human|Cyclin-Dependent Kinase 2|G1 Phase|DNA Replication|Ubiquitin-Protein Ligases|Ubiquitin|Interphase | |
10548543 Biochem. J. 1999 PMC1220623 Animals|Rats|Humans|acyl CoA synthetase 5|*Coenzyme A Ligases|long-chain-fatty-acid-CoA ligase|Base Sequence|Amino Acid Sequence|cDNA|Cloning, Molecular|mRNA|Gene Expression|Sequence Homology, Amino Acid|Fatty Acids|Saccharomyces cerevisiae Proteins|Repressor Proteins|Reticulocytes | |
10549281 Mol. Cell 1999 Animals|CTNNB1 protein, human|*beta Catenin|*Wnt Signaling Pathway|Transcription Factors|TCF Transcription Factors|Trans-Activators|HMGB Proteins|Wnt Proteins|Xenopus Proteins|Homeodomain Proteins|Xenopus laevis|High Mobility Group Proteins|Zebrafish Proteins|Body Patterning|Repressor Proteins|Transcription Factor 7-Like 1 Protein|Gene Expression Regulation, Developmental|Lymphoid Enhancer-Binding Factor 1 | |
10549282 Mol. Cell 1999 SMAD3 protein, human|*Smad3 Protein|TGFbeta|Smad2 Protein|Trans-Activators|Tumor Suppressor Proteins|Transcription, Genetic|Cyclin-Dependent Kinase Inhibitor p15|Signal Transduction|Activation, Transcriptional|Cyclin-Dependent Kinase Inhibitor p16|*Oncogene Proteins|Protein Binding|Promoter Regions, Genetic | |
10549295 Mol. Cell 1999 Animals|Hedgehog Proteins|*Heparan Sulfate Proteoglycans|Wnt1 Protein|Drosophila Proteins|Signal Transduction|Morphogenesis|Drosophila|Gene Expression Regulation, Developmental|CD44 protein, human|*Hyaluronan Receptors|Proto-Oncogene Proteins|Membrane Proteins | |
10549626 Immunity 1999 Animals|Mice|TLR2 protein, human|*Toll-Like Receptor 2|*Toll-Like Receptor 4|*Gram Positive Bacteria|lipoteichoic acid|Teichoic Acids|Lipopolysaccharides|Peptidoglycan|Toll-Like Receptors|Gram-Negative Bacteria|Membrane Glycoproteins|Cell Wall|Drosophila Proteins|NF-kappa B|Signal Transduction|Staphylococcus aureus|Tlr2 protein, mouse|Tlr4 protein, mouse | |
10549853 Biol. Pharm. Bull. 1999 Animals|Rabbits|glutathione peroxidase GPX1|*Glutathione Peroxidase|*Macrophages, Alveolar|arachidonic acid 5-hydroperoxide|Leukotrienes|5-hydroxy-6,8,11,14-eicosatetraenoic acid|Hydroxyeicosatetraenoic Acids|Lipid Hydroperoxide|Glutathione|Arachidonic Acid|Peroxidases|Peroxidase|Lung|*Inflammation Mediators | |
10550055 Science 1999 BRCA1 protein, human|*BRCA1 Protein|*Phosphorylation|ATM protein, human|*ATM Protein|Tumor Suppressor Proteins|Cell Cycle Proteins|DNA Damage|Ataxia-Telangiectasia|DNA Repair|DNA-Binding Proteins|Nuclear Proteins|Ionizing Radiation|Cell Line|Serine|Protein Binding | |
10551777 Mol. Endocrinol. 1999 *Receptors, Somatotropin|cytokine inducible SH2-containing protein|SOCS Proteins|STAT5A protein, human|STAT5 Transcription Factor|JAK2 protein, human|Janus Kinase 2|*Transductions, Signal|SOCS2 protein, human|somatotropin-binding protein|DNA-Binding Proteins|Trans-Activators|Phosphorylation|Repressor Proteins|Immediate-Early Proteins|SH2 Domain|Growth Hormone|Suppressor of Cytokine Signaling 1 Protein | |
10551832 J. Biol. Chem. 1999 Animals|*Dimerization|ABCD1 protein, human|Adrenoleukodystrophy Protein|Adrenoleukodystrophy|ATP Binding Cassette Transporter, Subfamily D|ATP-Binding Cassette Transporters|Peroxisomes|Yeast Two-Hybrid System|Membrane Proteins|Adenosine Triphosphate | |
10551863 J. Biol. Chem. 1999 Mice|Animals|NOTCH2 protein, human|*Receptor, Notch2|*Notch Receptors|JAG1 protein, human|*Jagged-1 Protein|Serrate-2 Protein|Serrate-Jagged Proteins|NOTCH3 protein, human|Receptor, Notch3|Ligands|Membrane Proteins|Intercellular Signaling Peptides and Proteins|Receptor, Notch1|Calcium-Binding Proteins|Transcription Factors|Receptor, Notch4|Intracellular Signaling Peptides and Proteins|Protein Binding | |
10551868 J. Biol. Chem. 1999 Humans|*Cytosine|Kinetics|*B-DNA|*Methyltransferases|Substrate Specificity|DNA (Cytosine-5-)-Methyltransferases|DNA Methylation|S-Adenosylmethionine|DNA|Baculovirus|cytidylyl-3'-5'-guanosine|Dinucleoside Phosphates|Oligodeoxyribonucleotides | |
10551873 J. Biol. Chem. 1999 Humans|*Substrate Specificity|*Matrix Metalloproteinase 17|*Catalytic Domain|progelatinase|Gelatinases|Enzyme Precursors|Matrix Metalloproteinases|Metalloproteinases, Membrane-Type Matrix|Amino Acid Sequence|Proteins|MMP Inhibitors|Cloning, Molecular|Catalysis|Hydrolysis | |
10553003 J. Lipid Res. 1999 Humans|glycerone-phosphate O-acyltransferase|*Ether|Chondrodysplasia Punctata, Rhizomelic|alkylglycerone-phosphate synthase|*Alkyl and Aryl Transferases|Acyltransferases|Amino Acid Sequence|Molecular Structure|cDNA|*Protein Deficiency|Microbodies|Point Mutation|Cell Line|Amino Acid Substitution|*Ethers|Fibroblasts|Sequence Homology, Amino Acid|*Lipids | |
10555141 Cell 1999 Humans|Animals|Mice|*B-DNA|*Methyltransferases|DNA methyltransferase 3B|*DNA (Cytosine-5-)-Methyltransferases|DNA Methylation|*DNA Modification Methylases|*Mammals|Embryonic Stem Cells|Mutations | |
10555148 Cell 1999 Humans|PTEN protein, human|*PTEN Phosphohydrolase|*Genes, Tumor Suppressor|Amino Acid Sequence|Binding Sites|Catalytic Domain|*Biochemical Phenomena|Phosphatidylinositols|Sequence Homology, Amino Acid|*Membrane|Mutation|Tumor Cells, Cultured|Phosphoinositide Phosphatases | |
10556282 Hum. Mol. Genet. 1999 *Tudor Domain|Neurodegenerative Diseases|*Muscular Atrophy, Spinal|SMN Complex Proteins|Ribonucleoproteins, Small Nuclear|Spliceosomes|*Motor Neurons|*RNA Splicing|RNA-Binding Proteins|Ribonucleoprotein|Nerve Tissue Proteins|snRNP Core Proteins|Protein Binding|DEAD Box Protein 20|Cyclic AMP Response Element-Binding Protein|Cytoplasm|DEAD-box RNA Helicases|*Neurons, Efferent | |
10556483 Biochim. Biophys. Acta 1999 Animals|Humans|Caco-2 Cells|Organic Anion Transporters, Sodium-Dependent|Sodium-Coupled Vitamin C Transporters|*Vitamin C|*Sodium|Symporters|Amino Acid Sequence|Biological Transport|*Membrane Transport Proteins|cDNA|*RNA Splicing|Kinetics|Xenopus laevis|cDNA Library|Cloning, Molecular | |
10556521 FEBS Lett. 1999 Humans|*Sodium-Coupled Vitamin C Transporters|Organic Anion Transporters, Sodium-Dependent|Symporters|Ascorbic Acid|Sodium|cDNA Library|Biological Transport|Active Transport|Cloning, Molecular|Cell Line|Transfection|Phorbol Myristate Acetate|Oocytes | |
10556826 Eur. J. Immunol. 1999 Humans|*src Homology Domains|B cell linker protein|Adaptor Proteins, Signal Transducing|Tec protein-tyrosine kinase|*Protein-Tyrosine Kinases|SLP-76 signal Transducing adaptor proteins|Phosphoproteins|Phospholipase C gamma|Phosphorylation|BTK protein, human|Agammaglobulinaemia Tyrosine Kinase|Intracellular Signaling Peptides and Proteins|Syk Kinase|Signal Transduction|Carrier Proteins|B Cells|Lymphocyte Activation|Jurkat Cells | |
10557210 Genes Dev. 1999 PMC317143 Animals|*Protein Kinase A|*Hedgehog Proteins|Transcription Factor|*Signal Transduction|Drosophila|Drosophila Proteins|AKT1 protein, human|*Protein Kinase B|DNA-Binding Proteins|Drosophila melanogaster|Phosphorylation|Cell Cycle Proteins|Repressor Proteins|Protein Processing, Post-Translational|Ubiquitin-Protein Ligases|Animals, Genetically Modified | |
10558993 Science 1999 *PPAR gamma|peroxisome-proliferator-activated receptor-gamma coactivator-1|NCOA1 protein, human|Steroid Receptor Coactivator 1|Nuclear Proteins|Acetyltransferases, Histone|Trans-Activators|*Gene Expression Regulation|CREBBP protein, human|CREB-Binding Protein|DNA-Binding Proteins|Binding Sites|Transcriptional Activation|EP300 protein, human|E1A-Associated p300 Protein|PPARGC1A protein, human|Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha|Protein Binding | |
10559189 J. Biol. Chem. 1999 *Transcription Factors|*Histone Deacetylases|Homeodomain Proteins|Repressor Proteins|Nuclear Protein|Basic Helix-Loop-Helix Transcription Factors|Transcription, Genetic|HIPK2 protein, human|Carrier Proteins|Protein-Serine-Threonine Kinases|Binding Sites|Amino Acid Sequence|Protein Binding|trichostatin A|Hydroxamic Acids|Cell Nucleus|Histone Deacetylase Inhibitor | |
10559216 J. Biol. Chem. 1999 Animals|Kinetics|Heterogeneous-Nuclear Ribonucleoprotein D|*RNA, Small Nuclear|mRNA|Protein Binding|Nucleic Acid Conformation|Binding Sites|3' Untranslated Regions|Heterogeneous Nuclear Ribonucleoprotein D0|Cytoplasm|Gene Expression Regulation | |
10559218 J. Biol. Chem. 1999 Humans|Animals|Rats|Systemic carnitine deficiency|*Carnitine|Solute Carrier Family 22 Member 5|Organic Cation Transport Proteins|*Mutations|Membrane Proteins|Hyperammonemia|Biological Transport|Kinetics|Sodium|Tetraethylammonium|*Ion Transport|Muscular Diseases|Active Transport|Cardiomyopathies|Amino Acid Sequence|Cations | |
10559246 J. Biol. Chem. 1999 Humans|Mice|Animals|Chlorocebus aethiops|*Guanine Nucleotide Exchange Factor|NIH 3T3 Cells|RHOA protein, human|rhoA GTP-Binding Protein|RASGRF1 protein, human|*ras-GRF1|cdc42 GTP-Binding Protein|Amino Acid Sequence|Signal Transduction|Sequence Homology, Amino Acid|Protein Binding|3T3 Cells|COS Cells | |
10559261 J. Biol. Chem. 1999 Humans|*Proliferating Cell Nuclear Antigen|Flap Endonuclease 1|DNA Polymerase delta|Base Excision Repair|Pol beta protein, human|DNA Polymerase beta|DNA Ligase I|Replication Factor C|DNA Replication|DNA Ligases|DNA-(Apurinic or Apyrimidinic Site) Lyase|Deoxyribonuclease IV (Phage T4-Induced)|Replication Protein A|Endodeoxyribonucleases|Exodeoxyribonucleases|DNA-Binding Proteins|Endonucleases | |
10559837 Braz. J. Med. Biol. Res. 1999 Animals|Chlorocebus aethiops|NOS3 protein, human|*Nitric Oxide Synthase Type III|Endothelial Cells|Caveolin 1|COS Cells|Calmodulin|Nitric Oxide Synthase|Membrane Proteins|Endothelium, Vascular|Cell Membrane|Caveolae|Transductions, Signal|Acylation|Cytosol|Bradykinin|*Translocation, Genetic|Transfection | |
10559856 Nat. Cell Biol. 1999 Animals|*Coated Pits, Cell-Membrane|Clathrin|Endocytosis|Clathrin-Coated Vesicles|Plasma Membrane|latrunculin B|Thiazolidines|Actin|Green Fluorescent Proteins|Bridged Bicyclo Compounds, Heterocyclic|Microscopy, Fluorescence|Luminescent Proteins|Cell Line | |
10559861 Nat. Cell Biol. 1999 amphiphysin|*Dynamin|*Endocytosis|*Nerve Tissue Proteins|Clathrin|Dynamin-1|GTP Phosphohydrolases|Synaptic Vesicles|Guanosine Triphosphate|Synapses|Amino Acid Sequence|Liposomes | |
10559883 Nat. Cell Biol. 1999 Cricetinae|Animals|bis(monoacylglyceryl)phosphate|*Endosomes|*Monoglycerides|*Lysophospholipids|*Biological Transport|*Intracellular Membranes|Niemann-Pick Disease, Type C|Endocytosis|Cholesterol|Lysosomes|Cell Membrane|Protein Transport|Carrier Proteins|Lipoproteins, Low-Density|CHO Cells|Fibroblasts | |
10559916 Nat. Cell Biol. 1999 Animals|CDKN1B protein, human|*Cyclin-Dependent Kinase Inhibitor p27|*Ubiquitin|*S-Phase Kinase-Associated Proteins|Cyclin-Dependent Kinases|Ubiquitins|Phosphorylation|Cyclins|Ligase, Ubiquitin-Protein|Microtubule-Associated Proteins|Cyclin-Dependent Kinase 2|Cell Cycle|Cell Division|Cyclin E|Protein Binding | |
10559936 Nat. Cell Biol. 1999 Chlorocebus aethiops|Animals|LIMK1 protein, human|*Lim Kinases|*p21-Activated Kinases|*Actins|*Cytoskeleton|Phosphorylation|Microfilament Proteins|Protein Kinases|cdc42 GTP-Binding Protein|Signal Transduction|Enzyme Activation|COS Cells|Transcription Factors | |
10559940 Nat. Cell Biol. 1999 *ADP-Ribosylation Factor|*PtdIns|*Phosphatidylinositol 4,5-Diphosphate|*Golgi Complex|*1-Phosphatidylinositol 4-Kinase|phosphatidylinositol 4-phosphate|Phosphatidylinositol Phosphates|ADP-Ribosylation Factor 1|Intracellular Membranes|1-phosphatidylinositol-4-phosphate 5-kinase|Phosphotransferases (Alcohol Group Acceptor)|Phospholipase D|Inositol Phosphates|*Central Nervous System Stimulants | |
10559958 Nat. Cell Biol. 1999 *Lectins|*Glycoproteins|*Carrier Proteins|Endoplasmic Reticulum|Mannose-Specific Lectin|Protein Transport|Membrane Proteins|Golgi Apparatus|Vesicular Transport Proteins|Protein Binding|Biological Transport|Carbohydrate|CTSZ protein, human|Cathepsin Z | |
10559959 Nat. Cell Biol. 1999 Animals|*SNARE|*Membrane Fusion|*ATPase|N-Ethylmaleimide-Sensitive Factor|Golgi Apparatus|Vesicular Transport Proteins|Carrier Proteins|Mutation|Drosophila | |
10559964 Nat. Cell Biol. 1999 *Cytosol|*Class I Major Histocompatibility Molecules|Antigen Processing|*Antigens|Histocompatibility Antigens Class II|Dendritic Cells|Ovalbumin|T-Lymphocytes, Cytotoxic|Peptides | |
10559986 Nat. Cell Biol. 1999 Humans|Chlorocebus aethiops|Animals|*COPI|*Golgi Complex|*Endoplasmic Reticulum|(T,G)-A-L|Peptides|KDEL receptor|Receptors, Peptide|rab GTP-Binding Proteins|Secretory Pathway|Vero Cells|HeLa Cells|Cytosol|COP1 protein, human|*Glatiramer Acetate|*Ubiquitin-Protein Ligases|Shiga Toxin 1 | |
10562278 J. Cell Biol. 1999 PMC2156170 Humans|*Golgi Apparatus|*Endoplasmic Reticulum|Rab6 protein|rab GTP-Binding Proteins|Protein Transport|Coat Protein Complex I|*Biological Transport|KDEL receptor|Receptors, Peptide|HeLa Cells|COP-Coated Vesicles|Shiga Toxin | |
10562279 J. Cell Biol. 1999 PMC2156163 Humans|Peroxins|PTS1 Receptor|Peroxisomes|*Protein Transport|Zellweger Syndrome|Integral Membrane Protein|*Binding Proteins|Arabidopsis Proteins|Arabidopsis|Receptors, Cytoplasmic and Nuclear|Mutation|Amino Acid Sequence|PEX12 protein, human|PEX10 protein, human|PEX5 protein, Arabidopsis | |
10562299 J. Clin. Invest. 1999 PMC409835 Dogs|Animals|*Allergen|*Interleukin-9|IL 13|Mucin 5AC|Th2 Cell|*Cells, Epithelial|Asthma|MUC1 protein, human|*Mucin-1|Respiratory Mucosa|Lung|Allergy|Goblet Cells|Cytokines|Cultured Cells|Bronchoalveolar Lavage Fluid | |
10562567 EMBO J. 1999 PMC1171718 Humans|*Recombinase|*Meiosis|DMC1 protein, human|DNA-Binding Proteins|Cell Cycle Proteins|Rec A Protein|DNA, Single-Stranded|Rad51 Recombinase|Adenosine Triphosphatases|Recombination, Genetic|Nucleoprotein|Heteroduplex DNA|DNA | |
10564087 Am. J. Physiol. 1999 Animals|Cricetinae|Humans|CHO Cells|Cricetulus|4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid|Chloride Channels|Chlorides|Transfections|Patch-Clamp Techniques|Phosphorylation|DNA, Complementary|mRNA|*Skeletal Muscles | |
10564231 Am. J. Physiol. 1999 Humans|Rats|Animals|In Situ Hybridization, Fluorescence|AQP9 protein, human|*Aquaporins|Amino Acid Sequence|Ion Channels|Base Sequence|Sequence Alignment|Cloning, Molecular|Introns|DNA, Complementary|Liver|Tissue Distribution|RNA, Messenger|Exons|Aqp9 protein, rat | |
10564271 Mol. Biol. Cell 1999 PMC25679 Animals|*ATF6 Transcription Factor|*Proteolysis|*Endoplasmic Reticulum Stress|Transcription Factor|*Membrane Proteins|DNA-Binding Proteins|Endoplasmic Reticulum|Nuclear Protein|Molecular Chaperones|Folding, Protein|Heat-Shock Proteins|Cell Nucleus|Unfolded Protein Response|*Mammals|Saccharomyces cerevisiae | |
10564661 J. Cell. Sci. 1999 Adult|Humans|Mice|Animals|Hedgehog Proteins|*Transcription Factor|Zinc Finger Protein GLI1|*Zinc Finger|Kruppel-Like Transcription Factors|Oncogene Proteins|Drosophila Proteins|Signal Transduction|Trans-Activators|Repressor Proteins|Gene Expression Regulation, Developmental|Drosophila|Transcription, Genetic|Vertebrates|Zinc | |
10564664 J. Cell. Sci. 1999 Humans|*Caspase 7|*Caspase 6|CASP3 protein, human|*Caspase 3|*Cleavers|*Caspases|*Apoptosis|Cell Death|HeLa Cells|F-Actin|Microfilament Proteins|Carrier Proteins|Microfilaments|GAS2 protein, human | |
10564809 Gene 1999 Animals|Humans|Cattle|Mice|*Alternative Splicing|Exons|Intron|Base Sequence|Amino Acid Sequence|DNA|Cloning, Molecular|Protein Isoforms|DNA, Complementary|Chromosome Mapping|Sequence Homology, Nucleic Acid|Transcription, Genetic|Retina|Retinitis Pigmentosa|Photoreceptor Cells|Sequence Analysis, DNA|RNA, Messenger|Sequence Homology, Amino Acid | |
10567350 J. Biol. Chem. 1999 Humans|Animals|*Selenocysteine|*DNA Transposable Elements|Selenoproteins|Amino Acid Sequence|Base Sequence|3' Untranslated Regions|Selenium|TYRP1 protein, human|Sequence Homology, Amino Acid|Nucleic Acid Conformation|Protein Biosynthesis|*Mammals|*Membrane Glycoproteins|*Algorithm|Computer Program|cDNA | |
10567352 J. Biol. Chem. 1999 Mice|Animals|phosphatidylinositol 3-phosphate|*Saccharomyces cerevisiae|*Phosphatidylinositol 4,5-Diphosphate|*Schizosaccharomyces|*Phosphatidylinositol 3-Kinases|*Phosphate|phosphatidylinositol 4-phosphate|*Phosphatidylinositol Phosphates|phosphatidylinositol 5-phosphate|Saccharomyces cerevisiae Proteins|Vacuole|Phosphatidylinositol|*Yeast, Dried|Phosphotransferases (Alcohol Group Acceptor)|Protein Transport|Amino Acid Sequence|Sequence Homology, Amino Acid|Membrane Proteins | |
10567358 J. Biol. Chem. 1999 Animals|Rats|Humans|epsin|*Adaptor Proteins, Vesicular Transport|Clathrin|EPS15 protein, human|Adaptor Proteins, Signal Transducing|Clathrin-Coated Vesicle|Endocytosis|Vesicular Transport Proteins|Phosphoproteins|Intracellular Signaling Peptides and Proteins|Membrane Proteins|Calcium-Binding Proteins|Neuropeptides|Protein Binding|Amino Acid Sequence|Binding Sites | |
10567359 J. Biol. Chem. 1999 *Phospholipase C gamma2|*Glycosylphosphatidylinositols|*Hydrolysis|EPO protein, human|*Erythropoietin|*Epoetin Alfa|Erythropoietin Receptor|*Protein Binding|Phosphorylation|Tyrosine|*Protein Transport|Enzyme Activation|Signal Transduction|Isoenzymes | |
10567369 J. Biol. Chem. 1999 *Phosphorylation|MAPK1 protein, human|*Mitogen-Activated Protein Kinase 1|*MAP Kinase Signaling System|*Protein Binding|MAP Kinase Kinase 1|PAK1 protein, human|p21-Activated Kinases|Mitogen-Activated Protein Kinases|Binding Site|Proto-Oncogene Proteins c-raf|Enzyme Activation|Amino Acid Sequence|Proto-Oncogene Proteins | |
10567430 J. Biol. Chem. 1999 Chlorocebus aethiops|Animals|Cattle|Humans|HEK293 Cells|*G-Protein-Coupled Receptor Kinases|Signal Transduction|beta-Adrenergic Receptor Kinases|RGS Proteins|GTP-Binding Protein alpha Subunits, Gq-G11|Cyclic AMP-Dependent Protein Kinases|G-Protein-Coupled Receptors|Phospholipase C beta|Phosphorylation|Protein Binding|COS Cells|GTP-Binding Protein alpha Subunits|*Protein Domains | |
10567546 Mol. Cell. Biol. 1999 PMC84905 Humans|Mice|Animals|*Methyltransferases|DNA methyltransferase 3B|*DNA (Cytosine-5-)-Methyltransferases|DNA Methylation|Cytosine|*DNA Modification Methylases|Plasmids|Moloney murine leukemia virus | |
10567687 FEBS Lett. 1999 Humans|Mice|Animals|Swine|pantetheinase|*Amidohydrolases|*GPI-Linked Proteins|Biotinidase|Amino Acid Sequence|Cell Adhesion Molecules|Sequence Homology, Amino Acid|Multigene Family|Peptides|VNN2 protein, human | |
10568829 Int. J. Oncol. 1999 Humans|FGFR3 protein, human|*Receptor, Fibroblast Growth Factor, Type 3|*Translocation, Genetic|*Multiple Myeloma|FGF12 protein, human|*Fibroblast Growth Factor|Oncogene|Oncogene Proteins, Fusion|CCND1 protein, human|Cyclin D1|Gene Expression Regulation, Neoplastic|RNA, Messenger|Japan | |
10570149 Proc. Natl. Acad. Sci. U.S.A. 1999 PMC24141 Humans|TP53 protein, human|*Tumor Suppressor Protein p53|*Phosphorylation|MDM2 protein, human|Proto-Oncogene Proteins c-mdm2|*DNA Damage|Nuclear Protein|Cell Cycle Proteins|Tumor Suppressor Proteins|Ataxia Telangiectasia Mutated Proteins|DNA-Binding Proteins|Proto-Oncogene Proteins|Serine|Ionizing Radiation|Cell Nucleus | |
10570274 J. Immunol. 1999 myo-inositol-1 (or 4)-monophosphatase|*Phosphorylation|*Receptors, Antigen, B-Cell|GRB2 protein, human|GRB2 Adaptor Protein|*Phosphoric Monoester Hydrolases|src Homology Domain|Signal Transduction|Shc Signaling Adaptor Proteins|Binding Sites|Adaptor Proteins, Vesicular Transport|Protein Binding|Src Homology 2 Domain-Containing, Transforming Protein 1|Ligands|Tyrosine|B-Lymphocytes | |
10570912 J. Hum. Genet. 1999 Male|Humans|alpha-1,3-mannosylglycoprotein beta-1,4-N-acetylglucosaminyltransferase|*Acetylglucosamine|N-Acetylglucosaminyltransferases|*Uridine Diphosphate N-Acetylglucosamine|Cloning, Molecular|Amino Acid Sequence|Base Sequence|Blotting, Northern|Transfection|Cell Line|Open Reading Frame|Exons|*Glycosyltransferases|Mannosides | |
10570971 Gene 1999 Animals|Cattle|ROCK1 protein, human|*rho-Associated Kinases|*Drosophila|Myosin Phosphatase|Myosin Light Chain|Phosphorylation|Amino Acid Sequence|Base Sequence|DNA Primers|GTP-Binding Proteins|Actins|Cloning, Molecular|DNA, Complementary|Protein Binding | |
10571037 Gene 1999 Humans|Animals|*TRF2 Protein|*Telomeres|*Chickens|Telomeric Repeat Binding Protein 1|Amino Acid Sequence|Cloning, Molecular|DNA-Binding Proteins|Binding Sites|Protein Binding|Sequence Homology, Amino Acid | |
10571241 Neuron 1999 Mice|Animals|VLDL receptor|*Low Density Lipoprotein Receptor-Related Protein-1|*Phosphorylation|reelin protein|*Cell Adhesion Molecules, Neuronal|*Receptors, LDL|low density lipoprotein receptor-related protein 8|*LDL-Receptor Related Proteins|*Serine Endopeptidases|*Extracellular Matrix Proteins|*Nerve Tissue Proteins|*Low Density Lipoprotein Receptor-Related Protein-2|Neurons|Cell Movement|Signal Transduction|Cerebral Cortex|*Cell Communication|Protein Binding | |
10571941 Hum. Mutat. 1999 Humans|Child|Cystinosis, Late-Onset Juvenile or Adolescent Nephropathic Type|*Cystinosis|CTNS protein, human|Amino Acid Transport Systems, Neutral|*Mutations|Membrane Proteins|Cystine|Fanconi Syndrome|Glycoproteins|Point Mutation|Gene Deletion|Mutations, Missense|RNA|Kidney Diseases|Nephrotic Syndrome | |
10571948 Hum. Mutat. 1999 Infant|Humans|Infant, Newborn|IgA receptor|Congenital Deficiency of Pulmonary Surfactant Protein B|*Pulmonary Surfactant-Associated Protein B|*Pulmonary Alveolar Proteinosis|*Heterozygote|Pulmonary Surfactants|Respiratory Distress Syndrome, Newborn|Homozygote|Mutation|Lung|Bronchoalveolar Lavage Fluid|Proteolipids|Surface-Active Agents | |
10572046 Development 1999 Humans|Pregnancy|Female|Mice|Animals|*Genes, Homeobox|*Spleen|Hedgehog Proteins|Homeodomain Proteins|SOX9 protein, human|SOX9 Transcription Factor|RUNX2 protein, human|Core Binding Factor Alpha 1 Subunit|*Bones|Chondrogenesis|*Embryonic Development|Trans-Activators|Mice, Knockout|Chondrocyte|Cell Differentiation|Gene Expression Regulation, Developmental|FGFR3 protein, human|Receptor, Fibroblast Growth Factor, Type 3 | |
10572048 Development 1999 Animals|*Drosophila|*Frizzled Receptors|Photoreceptor Cells, Invertebrate|Drosophila Proteins|Receptors, Notch|Cell Polarity|Receptors, G-Protein-Coupled|Signal Transduction|Membrane Proteins|Cell Lineage|Cell Differentiation|Eye|notch protein, Drosophila | |
10572074 Blood 1999 Humans|CD47 protein, human|*CD47 Antigen|TYRP1 protein, human|*Membrane Glycoproteins|Receptors, Immunologic|*Cell Adhesion|Antigens, Differentiation|Antigens, CD|Neural Cell Adhesion Molecule L1|Neural Cell Adhesion Molecules|Signal Transduction|Recombinant Fusion Proteins|IgA receptor|Cell Movement|Integrins|Hematopoietic Stem Cells|Antibodies, Monoclonal|Ligands | |
10572166 Nucleic Acids Res. 1999 PMC148766 *Ku Autoantigen|PRKDC protein, human|*DNA-Activated Protein Kinase|*DNA Repair|Nuclear Proteins|*DNA|Antigens, Nuclear|DNA Helicases|DNA-Binding Proteins|DNA Damage|Phosphorylation|Protein Conformation|Protein Binding|*Translocation, Genetic | |
10573420 Nature 1999 Mice|Animals|*Mycobacterium tuberculosis|Tuberculosis|Virulence|phthiocerol dimycocerosate|*Lipids|Bacterial Proteins|Mutagenesis, Insertional|DNA Transposable Elements|Genes, Bacterial|Cell Wall|Lung|Macrophages|*Diagnostic Tests, Routine | |
10574707 J. Cell. Sci. 1999 Nuclear Proteins|Promyelocytic Leukemia Protein|Transcription Factors|SUMO Protein|Tumor Suppressor Proteins|Ubiquitins|Immediate-Early Proteins|*Intranuclear Inclusion Bodies|Ubiquitin-Protein Ligases|Cell Cycle|*Cell Cycle Checkpoints|Mitosis | |
10574788 Structure 1999 *Hydrolysis|*Proto-Oncogene Proteins p21(ras)|*Water|triphosphoric acid|*Guanine|*Proteins|Protein Conformation|*Polyphosphates|Guanosine Triphosphate|Hydrogen Bonding|Crystallography, X-Ray|Models, Molecular|Binding Sites|GTPases|Catalysis | |
10574799 Structure 1999 *Kinesin|*Microtubules|Protein Conformation|Models, Molecular|*Dyneins|Drosophila Proteins|Crystallography, X-Ray|Adenosine Diphosphate|*Myosins|Structure-Activity Relationship|Dimerization | |
10574949 J. Biol. Chem. 1999 FGFR1 protein, human|Receptor, Fibroblast Growth Factor, Type 1|FGFR3 protein, human|Receptor, Fibroblast Growth Factor, Type 3|Fibroblast Growth Factors|Receptor, Fibroblast Growth Factor, Type 2|Amino Acid Sequence|Signal Transduction|Protein Binding|Phosphorylation|Binding Sites|Ligands|Substrate Specificity|Kinetics|Cell Line|Immunoglobulin | |
10579907 Exp. Cell Res. 1999 *Phospholipase C gamma|*Transductions, Signal|Phosphorylation|Isozymes|Enzyme Activation|Protein Kinase C|Adaptor Proteins, Signal Transducing|Carrier Proteins|Protein Binding|Second Messenger|Tyrosine|Transfection | |
10579975 Gastroenterology 1999 Mice|Animals|*Genes, Homeobox|*Gastrointestinal Microbiome|Homeodomain Proteins|Neural Crest|Transcription Factors|Gene Expression Regulation, Developmental|Morphogenesis|Intestinal Mucosa|In Situ Hybridization|*Intestine, Small|Gene Expression | |
10580059 J. Gen. Virol. 1999 Animals|*Zanamivir|*Neuraminidase|*Influenza B virus|Antiviral Agents|Sialic Acids|Enzyme Inhibitors|Hemagglutinin Glycoproteins, Influenza Virus|Guanidines|Influenza A virus|Hemagglutinin|Pyrans|Cell Line|Viral Plaque Assay|Glycosylation | |
10580105 FEBS Lett. 1999 Humans|*Lung Adenocarcinoma|Adenocarcinoma|Lung Neoplasms|*Lung|*Aspartic Acid Proteases|Aspartic Acid Endopeptidases|Biomarkers, Tumor|In Situ Hybridization|Blotting, Northern|Amino Acid Sequence | |
10580119 FEBS Lett. 1999 Animals|anthrax toxin|*Lipopolysaccharides|TNF protein, human|*Tumor Necrosis Factor-alpha|*Cleavers|*Antigens, Bacterial|*Bacterial Toxins|Bacillus anthracis|*Macrophages|MAP2K1 protein, human|MAP Kinase Kinase 1|Mitogen-Activated Protein Kinases|Phosphorylation|MAP Kinase, p38|Protein-Tyrosine Kinases|MAP Kinase Kinase 3|MAP Kinase Signaling System|Protein-Serine-Threonine Kinases | |
10581036 Nat. Genet. 1999 Humans|Adult|*Sialic Acid Storage Disease|Alleles|Lysosomal Storage Diseases|Symporters|Mutation|Sialic Acid|Genetic Linkage|Organic Anion Transporters|Chromosome Mapping|Finland | |
10581160 Biochem. Biophys. Res. Commun. 1999 CTNNB1 protein, human|*beta Catenin|*Glycogen Synthase Kinase 3 beta|*Axin Protein|*Phosphorylation|TCF Transcription Factors|Wnt Proteins|Signal Transduction|Trans-Activators|Binding Site|Transcription Factors|Glycogen Synthase Kinases|Calcium-Calmodulin-Dependent Protein Kinases|Adenomatous Polyposis Coli Protein|Repressor Proteins|Protein Binding|Zebrafish Proteins | |
10581243 EMBO J. 1999 PMC1171732 *TNF Receptor-Associated Factor 2|TBK1 protein, human|*Signal Transduction|NF-kappa B|I-kappa B Kinase|Mitogen-Activated Protein Kinases|RELA protein, human|Transcription Factor RelA|TNF Receptor-Associated Factor 5|Adaptor Proteins, Signal Transducing|TNF Receptor-Associated Factor 6|Phosphorylation|Tumor Necrosis Factor Receptor|*Gene Expression Regulation|Amino Acid Sequence|Binding Sites|Tumor Necrosis Factor-alpha|Motor Vehicles | |
10581249 EMBO J. 1999 PMC1171738 laminin 1|laminin gamma 1|*Laminin|*Agrin|*Binding Site|Protein Structure, Secondary|Amino Acid Sequence|Membranes, Basement|Protein Binding|Heparan Sulfate Proteoglycan|*Protein Domains|laminine|*Amino Acids, Diamino|Sequence Alignment|Protein Isoforms | |
10581255 EMBO J. 1999 PMC1171744 Humans|dolichyl-phosphate beta-D-mannosyltransferase|*Mannosyltransferases|*Congenital Disorders of Glycosylation|Saccharomyces cerevisiae|Glycosylation|Amino Acid Sequence|Mannose|Oligosaccharides|Endoplasmic Reticulum|Sequence Homology, Amino Acid|Sequence Alignment|Dolichol Monophosphate Mannose|Missense Mutation|Glycoproteins | |
10582871 Antimicrob. Agents Chemother. 1999 PMC89576 Adult|Male|Humans|abacavir|*HIV-1|*Dideoxynucleosides|reverse transcriptase, Human immunodeficiency virus 1|*HIV Reverse Transcriptase|*HIV Infections|Reverse Transcriptase Inhibitors|Anti-HIV Agents|Drug Therapy, Combination|Area Under Curve | |
10583376 Eur. J. Biochem. 1999 Humans|*Orexins|*Neuropeptide|*Hypothalamus|Receptors, Orexin|Intracellular Signaling Peptides and Proteins|Neuropeptide Y|Carrier Proteins|Amino Acid Sequence | |
10583407 Eur. J. Biochem. 1999 *Amyloid beta-Peptides|*Alzheimer Disease|*Glycosaminoglycans|Peptide Fragments|Amyloid Fibrils|Deposit, Amyloid|Heparitin Sulfate|Proteoglycans|Heparin|Circular Dichroism|Electron Microscopy|Chondroitin Sulfates|APP protein, human|Amyloid beta-Protein Precursor|Structure-Activity Relationship | |
10585413 J. Biol. Chem. 1999 diphosphoinositol polyphosphate phosphohydrolase|*Polyphosphates|*Acid Anhydride Hydrolases|nudix hydrolases|Pyrophosphatases|*Mutagenesis, Site-Directed|1-diphosphoinositol pentakisphosphate|Inositol Phosphates|Substrate Specificity|Amino Acid Sequence|Hydrolysis|Sequence Homology, Amino Acid|Kinetics|Sequence Alignments|Saccharomyces cerevisiae|Catalysis|Active Site | |
10585422 J. Biol. Chem. 1999 Rats|Animals|NGF protein, human|*Nerve Growth Factor|*Receptor, Adenosine A2A|*mRNA|*Adenosine|PC12 Cells|MAP2K3 protein, human|*MAP Kinase Kinase 3|Receptor, trkA|Mitogen-Activated Protein Kinase p38|Mitogen-Activated Protein Kinase 3|Mitogen-Activated Protein Kinase 1|Mitogen-Activated Protein Kinases|Downregulation|JNK Mitogen-Activated Protein Kinases|Signal Transduction|src Kinases|Phosphorylation | |
10585430 J. Biol. Chem. 1999 Animals|STAT5B protein, human|STAT5A protein, human|*STAT5 Transcription Factor|JAK2 protein, human|Janus Kinase 2|*Transductions, Signal|SOCS2 protein, human|SOCS Proteins|Growth Hormone Receptor|somatotropin-binding protein|DNA-Binding Proteins|*Tumor Suppressor Proteins|Trans-Activators|Phosphorylation|Immediate-Early Proteins|Repressor Proteins|Growth Hormone|TYRP1 protein, human | |
10585467 J. Biol. Chem. 1999 Mice|Animals|SREBF1 protein, human|*Sterol Regulatory Element Binding Protein 1|*Lipogenesis|*Gene Expression Regulation|Nuclear Protein|CCAAT-Enhancer-Binding Proteins|Cholesterol|mRNA|Fatty Acid Synthases|Triglycerides|Stearoyl CoA Desaturase|Liver|Fasting|Acetyl-CoA Carboxylase|Mice, Knockout|Diet|Fatty Acids | |
10585886 Biochem. J. 1999 PMC1220721 Rats|Animals|Humans|*Dicarboxylic Acid Transporters|*Mitochondria|Base Sequence|Carrier Proteins|Introns|Amino Acid Sequence|Exons|Cloning, Molecular|cDNA|Sequence Alignment|PCR|Sequence Homology, Amino Acid|DNA|DNA Primers|Nuclear Protein | |
10586060 J. Immunol. 1999 *Leukemia Inhibitory Factor Receptor|*Receptor, Oncostatin M|LIFR protein, human|*Leukemia Inhibitory Factor Receptor alpha Subunit|LIF protein, human|Inhibitory Factor, Leukemia|*Signal Transduction|Cytokine Receptor gp130|STAT3 protein, human|STAT3 Transcription Factor|OSMR protein, human|*Oncostatin M Receptor beta Subunit|Oncostatin M|cardiotrophin 1|Receptors, Cytokine|STAT1 protein, human|STAT1 Transcription Factor|JAK1 protein, human | |
10586089 J. Immunol. 1999 Humans|*NF-kappa B|STAT6 protein, human|*STAT6 Transcription Factor|CCL11 protein, human|*Chemokine CCL11|*Cells, Epithelial|Transcription Factors|Gene Expression Regulation|Promoter Regions, Genetic|Trans-Activators|Transcription, Genetic|Binding Sites|Activation, Transcriptional|Signal Transduction|Electrophoretic Mobility Shift Assay|TNFalpha|Interleukin-4|Protein Binding | |
10587441 Biochemistry 1999 Humans|*Phenylalanine|*Asparagine|GSTM3 protein, human|*Glutathione Transferase|*Catalysis|Protein Conformation|Substrate Specificity|Mutagenesis, Site-Directed|Amino Acid Sequence|Binding Sites|Kinetics|Crystallography, X-Ray|Amino Acid Substitution|Models, Molecular|Glutathione | |
10587520 J. Clin. Invest. 1999 PMC409866 Humans|*Transcription Factor|Homeobox Protein Nkx-2.5|Homeodomain Proteins|*Mutations|Congenital Heart Defects|Homeobox|Atrial Septal Defect|*Heart|Point Mutation|Phenotype|Ventricular Septal Defect|Mutation, Missense|Pedigree|Anomaly, Ebstein|Heterozygote|Heart Block|*Gene Expression Regulation | |
10587642 Nat. Cell Biol. 1999 SMAD2 protein, human|*Smad2 Protein|Transforming Growth Factor beta|UBB protein, human|*Ubiquitin|Signal Transduction|Smad3 Protein|Trans-Activators|Phosphorylation|Receptors, Transforming Growth Factor beta|Proteasome|Cell Nucleus|Transcription, Genetic|Cytoplasm | |
10588656 Mol. Biol. Cell 1999 PMC25756 Humans|loricrin|Membrane Proteins|envoplakin|Protein Precursors|*Plasma Membrane|involucrin|Keratinocytes|*Epithelium|Plakins|Epidermis|Peptides|Cultured Cells|Amino Acid Sequence|Desmoplakins|Proline-Rich Protein Domains|Electron Microscopy|Carcinoma, Squamous Cell | |
10588714 Proc. Natl. Acad. Sci. U.S.A. 1999 PMC24445 Animals|Mice|*Adrenergic Receptor, beta 2|*Teratocarcinoma|*Chimera|*Wnt Signaling Pathway|FZD2 protein, human|Frizzled Receptors|*Cell Differentiation|Wnt Proteins|G Proteins|Zebrafish Proteins|Endoderm|Receptors, Neurotransmitter|Zebrafish|Proto-Oncogene Proteins|Isoproterenol|Pertussis Toxin | |
10588945 J. Lipid Res. 1999 Male|Female|Humans|*cDNA|CYP7B1 protein, human|*Cytochrome P450 Family 7|*Steroid Hydroxylases|Cytochrome P-450 Enzyme System|CYP7A1 protein, human|Cholesterol 7alpha Hydroxylase|27-hydroxycholesterol|Hydroxycholesterols|mRNA|Promoter Regions, Genetic|Hydroxylation|Liver|Bile Acids|Cholesterol|Gene Expression Regulation, Enzymologic|Transfection|Introns | |
10590411 Muscle Nerve 1999 Humans|*DNA, Complementary|*Carrier Proteins|Lactate Transporter|Muscle, Skeletal|Lactic Acid|*Mutation|*Ion Transport | |
1059088 Proc. Natl. Acad. Sci. U.S.A. 1975 PMC432905 Rabbits|Humans|Animals|Guinea Pigs|*Thromboxanes|*Prostaglandin Endoperoxides|Platelet Aggregation|Platelets|Prostaglandins|Arachidonic Acids|Thromboxane A2|Serotonin|Peroxides|Thromboxane B2|prostaglandin G2|Prostaglandins G|Hydroxy Acids | |
10591629 J. Cell. Sci. 1999 Mice|Male|Animals|ROPN1 protein, human|rhophilin|*Sperm Flagellum|*Membrane Proteins|*rho GTP-Binding Proteins|spermadhesin|*Seminal Plasma Proteins|*Protein Binding|A Kinase Anchor Proteins|Spermatogenesis|Amino Acid Sequence|Spermatozoa|Testis|Yeast Two-Hybrid System|Cyclic AMP-Dependent Protein Kinases|cDNA | |
10593898 J. Biol. Chem. 1999 CHUK protein, human|*I-kappa B Kinase|NFKBIA protein, human|*NF-KappaB Inhibitor alpha|*Phosphorylation|*Catalytic Domain|NFKBIE protein, human|I kappa B Proteins|I kappa B beta protein|*Signal Transduction|peptide B|*Protein Precursors|NF-kappa B|RELA protein, human|Transcription Factor RelA|DNA-Binding Proteins|Kinetics|Amino Acid Sequence | |
10593899 J. Biol. Chem. 1999 *Adaptors, Clathrin|invariant chain|*Leucine|*Antigens, Differentiation, B-Lymphocyte|*Histocompatibility Antigens Class II|Adaptor Protein Complex 2|Adaptor Protein Complex 1|Adaptor Protein Complex alpha Subunits|Clathrin|*Protein Sorting|Adaptor Protein Complex 3|Membrane Proteins|Amino Acid Sequence|Endocytosis|Protein Binding | |
10593924 J. Biol. Chem. 1999 Cricetinae|Animals|*Osteopontin|SVVYGLR peptide|*Thrombin|CHO Cells|Chinese Hamster|*Integrins|*Oligopeptides|Cell Adhesion|neuronectin|Extracellular Matrix Proteins|Tenascin-C|Amino Acid Sequence|Binding Sites|Cell Movement|Transfections|Mutagenesis, Site-Directed|VCAM-1|Extracellular Matrix | |
10593988 J. Biol. Chem. 1999 Animals|Rats|Chlorocebus aethiops|*Inositol Polyphosphate 5-Phosphatases|Amino Acid Sequence|synaptojanin|Phosphatases|Base Sequence|COS-7 Cells|Cloning, Molecular|Phosphatidylinositol|Inositol Phosphates|DNA, Complementary|Substrate Specificity|Nerve Tissue Proteins|Cell Membrane|*Cell Surface Extensions | |
10596943 Arch. Histol. Cytol. 1999 Humans|*Microscopy, Electron, Scanning|*Osteosarcoma|*Extracellular Matrix|Collagen|*Biological Phenomena|Cell Line|Cultured Cells|*Skin | |
10597240 Oncogene 1999 *Cell Cycle Proteins|Transcription Factor DP1|Retinoblastoma-Binding Protein 1|E2F Transcription Factors|Binding Site|Promoter Regions, Genetic|Transcription, Genetic|E2F1 Transcription Factor|S Phase|Cell Cycle|Retinoblastoma Protein|DNA Sequence|Protein Binding|Transcriptional Activation|Cell Division|Double-Stranded DNA | |
10597252 Oncogene 1999 Humans|*c-jun N-Terminal Kinase|*Nuclear Factor-Kappab|TNF protein, human|Tumor Necrosis Factor-alpha|Signal Transduction|*Cell Proliferation|Mitogen-Activated Protein Kinases|Enzyme Activation|Apoptosis|CASP3 protein, human|Caspase 3|*Cell Cycle|HeLa Cells | |
10597289 Oncogene 1999 Humans|Female|*Microsatellite Instability|*Mutation Rate|*Endometrial Carcinoma|*Transcription Factor 7-Like 2 Protein|Mutations, Frameshift|Stomach Neoplasms|CTNNB1 protein, human|beta Catenin|Tumors, Colorectal|*Stomach|*Colon|DNA, Neoplasm|Mutations|Microsatellite Repeats | |
10597293 Oncogene 1999 Animals|Humans|Rabbits|CUL4A protein, human|Cullin 1|*Cullin Proteins|NEDD8 protein, human|*NEDD8 Protein|Ubiquitins|Cell Cycle Proteins|Ubiquitin|Saccharomyces cerevisiae Proteins | |
10597300 Oncogene 1999 *Tumor Suppressor Protein p53|*Lymphocytes, Null|Cell Cycle Proteins|Ataxia Telangiectasia|*Ionizing Radiation|Tumor Suppressor Proteins|Ataxia Telangiectasia Mutated Proteins|DNA-Binding Proteins|Phosphorylation|Transformed Cell Lines|Cell Line|DNA Damage|Phosphatidylinositol 3-Kinases|DNA | |
10600115 Biochemistry 1999 Animals|Swine|Humans|*Protein Phosphatase 2|*Leucine|*Protein O-Methyltransferase|Protein Methyltransferases|Amino Acid Sequence|Methylation|*Brain|*Biochemical Phenomena|Recombinant Proteins|Catalysis|Cloning, Molecular | |
10600378 J. Mol. Biol. 1999 *Kinetics|*Antigen Processing|Class I Major Histocompatibility Molecules|ATP Binding Cassette Transporter, Subfamily B, Member 3|ATP Binding Cassette Transporter, Subfamily B, Member 2|Protein Binding|ATP-Binding Cassette Transporters|Peptides|Amino Acid Sequence|Protein Conformation|Membrane Transport Proteins|Biological Transport|Antigens|Cell Membrane|Binding Site|Endoplasmic Reticulum|Adenosine Triphosphate|Cytotoxic T-Lymphocytes | |
10600384 J. Mol. Biol. 1999 Humans|PFN1 protein, human|*Profilins|*X-Rays|Contractile Proteins|Actin|Microfilament Proteins|Protein Binding|Binding Sites|Amino Acid Sequence|Hydrogen Bond|Proline|Peptides|Kinetics|Crystallization|SH3 Domains|Models, Molecular|Isoforms | |
10600773 Am. J. Physiol. 1999 Animals|Rats|Humans|Rabbits|Swine|potassium-chloride symporters|HEK293 Cells|*Symporters|*Cloning, Molecular|Amino Acid Sequence|Chlorides|N Ethylmaleimide|Potassium|Sequence Alignment|DNA, Complementary|Sodium | |
10601018 EMBO J. 1999 PMC1171759 *MAP Kinase Signaling System|TGFA protein, human|*Transforming Growth Factor alpha|*Phosphorylation|MAPK1 protein, human|Mitogen-Activated Protein Kinase 1|MAP Kinase, p38|Signal Transduction|N-Formyl-Methionyl-Leucyl-Phenylalanine|Mitogen-Activated Protein Kinase 3|Enzyme Activation|Tyrosine Kinase|Tumor Necrosis Factor-alpha|MAP Kinase Kinase 1|Mitogen-Activated Protein Kinase 14|Neutrophils|Imidazoles|*Membrane Proteins | |
10601273 J. Biol. Chem. 1999 *Glucokinase|glucokinase regulatory protein|*Nuclear Export Signals|*Active Transport, Cell Nucleus|*Carrier Proteins|GCKR protein, human|*Adaptor Proteins, Signal Transducing|*Liver|Intracellular Signaling Peptides and Proteins|Cell Nucleus|Cytoplasm|Glucose | |
10601278 J. Biol. Chem. 1999 Male|Animals|Rats|Humans|*Hydroxymethylglutaryl-CoA Reductase Inhibitors|*Organic Anion Transporters|Pravastatin|Biological Transport|*Liver|Simvastatin|Carrier Proteins|Taurocholic Acid|Thyroid Hormones|Anion Transport Proteins | |
10601301 J. Biol. Chem. 1999 Cricetinae|Humans|Animals|Rats|CHO Cells|Cricetulus|FADS2 protein, human|Fatty Acid Desaturases|Linoleoyl-CoA Desaturase|*Acids, Fatty|Cloning, Molecular|Open Reading Frame|mRNA|DNA, Complementary|Amino Acid Sequence|Gene Expression Regulation, Enzymologic|Diet|Liver | |
10601328 J. Cell Biol. 1999 PMC2168101 Animals|Chlorocebus aethiops|*Protein Kinase A|*Protein Tyrosine Phosphatases|MAPK1 protein, human|Mitogen-Activated Protein Kinase 1|PTPRR protein, human|*Receptor-Like Protein Tyrosine Phosphatases, Class 7|Mitogen-Activated Protein Kinases|Phosphorylation|Mitogen-Activated Protein Kinase 3|*MAP Kinase Signaling System|Intracellular Signaling Peptides and Proteins|Protein Tyrosine Phosphatases, Non-Receptor|Protein Binding|COS-7 Cells|*Protein Transport|p38 Mitogen-Activated Protein Kinases|Nerve Tissue Proteins|Binding Sites | |
10601333 J. Cell Biol. 1999 PMC2168095 Humans|Survival of Motor Neuron Complex|*Muscular Atrophy, Spinal|Nuclear Ribonucleoproteins, Small|*Gemini of Coiled Bodies|Spliceosomes|*Motor Neurons|Cell Nucleus|RNA-Binding Proteins|Cytoplasm|Nuclear Proteins|RNA Splicing|Sm Core Proteins|DEAD Box Protein 20|Nerve Tissue Proteins|*RNA|Ribonucleoproteins|DEAD-box RNA Helicases|Cyclic AMP Response Element-Binding Protein | |
10601334 J. Cell Biol. 1999 PMC2168098 Rats|Animals|*Membrane Proteins|*Glycosylation|*Endoplasmic Reticulum|*Ribosome|Calnexin|Molecular Chaperone|*Phosphoproteins|Endoplasmic Reticulum Stress|Protein Biosynthesis|*Cytoskeletal Proteins|Cell Line|Serp1 protein, rat | |
10602363 Eur. J. Hum. Genet. 1999 Humans|phosphomannomutase|Congenital disorder of glycosylation type 1A|*Escherichia coli|*Phosphotransferases (Phosphomutases)|*Congenital Disorders of Glycosylation|Homozygote|Heterozygote|Mutation|Alleles|Genotype | |
10604467 Nature 1999 Animals|Humans|CDK5 protein, human|*Cyclin-Dependent Kinase 5|tau Proteins|cyclin-dependent kinase-activating kinase|Neurons|Alzheimer Disease|Phosphorylation|Calpain|Brain|Cells, Cultured|Apoptosis | |
10604470 Nature 1999 Humans|Rats|Animals|*Ghrelin|*Growth Hormone|*Human Growth Hormone|Receptors, Ghrelin|*Pituitary Hormones, Anterior|*Stomach|Growth Hormone-Releasing Hormone|*Acylation|Amino Acid Sequence|Ligands|Pituitary Gland|*Upper Gastrointestinal Tract|Hypothalamus | |
10604473 Nature 1999 Animals|Mice|CDK5 protein, human|*Cyclin-Dependent Kinase 5|*Phosphorylation|*Dopamine|*Dopamine and cAMP-Regulated Phosphoprotein 32|*Signal Transduction|*Neurons|Protein Kinase|Nerve Tissue Proteins|Cyclic AMP|Phosphoproteins|Protein Phosphatase 1|Cyclic AMP-Dependent Protein Kinases|Calcineurin|Neostriatum|Threonine|Corpus Striatum|Kinetics | |
10604985 J. Immunol. 1999 TYRP1 protein, human|Surface Glycoproteins, Cell|SIRPB1 protein, human|*Receptors, Cell Surface|Receptors, Immunologic|Signal Transduction|SH2D3A protein, human|Adaptor Proteins, Signal Transducing|PTPN11 protein, human|Protein Tyrosine Phosphatase, Non-Receptor Type 11|SH2 Domain-Containing Protein Tyrosine Phosphatases|Antigens, Differentiation|Phosphorylation|Mitogen-Activated Protein Kinases|Neural Cell Adhesion Molecules|Protein Tyrosine Phosphatase, Non-Receptor Type 6|src Homology Domains|Protein-Tyrosine Kinases | |
10606205 J. Mol. Med. 1999 Humans|carcinoma-associated antigen 17-1A|*Epithelial Cell Adhesion Molecule|*Antigens, Neoplasm|Cell Adhesion Molecules|Edrecolomab|Antibodies, Monoclonal|Cadherins|Cell Adhesion|Cells, Epithelial|Biomarkers, Tumor|Tumor Cells, Cultured|Carcinomas|Epithelial Tissue|Germany | |
10606270 RNA 1999 PMC1369881 Humans|*Ribonucleoproteins, Small Nucleolar|Saccharomyces cerevisiae|Ribonucleoproteins, Small Nuclear|Saccharomyces cerevisiae Proteins|Cell Nucleolus|snoRNA|fibrillarin|Chromosomal Proteins, Non-Histone|Nuclear Proteins|Amino Acid Sequence|Protein Binding | |
10607567 Curr. Biol. 1999 Humans|Animals|PAK1 protein, human|*p21-Activated Kinases|nef Gene Products, Human Immunodeficiency Virus|Simian Immunodeficiency Virus|HIV-1|Cell Line|Alleles|nef protein, Human immunodeficiency virus 2|nef protein, Human immunodeficiency virus 1 | |
10608864 J. Biol. Chem. 1999 Animals|Mice|*Neural Cell Adhesion Molecule L1|*MAP Kinase Signaling System|Phosphorylation|MAPK1 protein, human|Mitogen-Activated Protein Kinase 1|Neural Cell Adhesion Molecules|Signal Transduction|NRCAM protein, human|Cell Adhesion Molecules|Leukocyte L1 Antigen Complex|Proto-Oncogene Proteins|Membrane Glycoproteins|Cell Movement | |
10608892 J. Biol. Chem. 1999 MDM2 protein, human|*Proto-Oncogene Proteins c-mdm2|p53 Tumor Suppressor Protein|Nuclear Proteins|Proto-Oncogene Proteins|Cell Cycle Proteins|Ubiquitination|Protein Binding|Amino Acid Sequence|RING Finger Domains|Transcriptional Activation|Tumor Cells, Cultured | |
10610717 Genomics 1999 Animals|Chlorocebus aethiops|Humans|*DNA, Complementary|ASAH1 protein, human|*Acid Ceramidase|In Situ Hybridization, Fluorescence|*Cloning, Molecular|Base Sequence|Introns|Amino Acid Sequence|Exons|Northern Blotting|Genome|Gene Expression|Transfections|Promoter Regions, Genetic|RNA, Messenger|COS-1 Cells|Green Fluorescent Proteins|Sequence Homology, Amino Acid | |
10610721 Genomics 1999 Mice|Humans|Animals|Amino Acid Sequence|Base Sequence|Sequence Alignment|DNA, Complementary|Chromosome Mapping|Cloning, Molecular|Epidermal Cells|Epidermis|Introns|Blotting, Northern|Sequence Homology, Amino Acid|Exons|*Membrane Transport Proteins|RNA, Messenger|Sequence Analysis, DNA|In Situ Hybridization, Fluorescence|Cells, Cultured | |
10611248 Mol. Cell. Biol. 1999 PMC85173 Humans|Mice|Animals|IQ motif containing GTPase activating protein 1|*Hyperplasia|ras GTPase-Activating Proteins|Binding Protein|cdc42 GTP-Binding Protein|Protein Binding|Amino Acid Sequence|Cell Cycle Proteins|F-Actin|*Gastritis, Hypertrophic|Sequence Homology, Amino Acid|Sequence Alignment|Calmodulin|IQGAP2 protein, human | |
10611283 Proc. Natl. Acad. Sci. U.S.A. 1999 PMC24718 Animals|Humans|*Type b, Cytochromes|*NAD|*Cytochromes b|Cytochrome b5|*NADH, NADPH Oxidoreductases|Cytochrome-B(5) Reductase|Cytochrome Reductases|Recombinant Proteins|Haem|Reductase|Cloning, Molecular|Base Sequence|cDNA|Amino Acid Sequence|Kinetics|Cytochrome c|PCR | |
10611312 Proc. Natl. Acad. Sci. U.S.A. 1999 PMC24747 Humans|Animals|*ras-Related GTPases|Nucleoside-Diphosphate Kinase|NM23 Nucleoside Diphosphate Kinases|Genes, Tumor Suppressor|Phosphorylation|Transcription Factors|Transfections|Tumor Cells, Cultured|Drosophila|*Cell Movement|*Diabetes Mellitus | |
10611474 FEBS Lett. 1999 Humans|NR3C2 protein, human|*Receptors, Mineralocorticoid|*Glucocorticoids|*Hydroxylation|Glucocorticoid Receptor|*Corticosteroids|Aldosterone|Mineralocorticoids|Cortisol|Steroid Receptor|Binding Sites|Transcriptional Activation|Transfection|Mutagenesis, Site-Directed | |
10611478 FEBS Lett. 1999 Rats|Animals|*Neurite Outgrowth|Neural Cell Adhesion Molecules|Neurites|PC12 Cells|Neurons|Leukocyte L1 Antigen Complex|Amino Acid Sequence|Recombinant Proteins|Signal Transduction|Transfection|oligomannoside|Oligosaccharides | |
10612401 Cell 1999 Animals|*Drosophila|Drosophila Proteins|CLOCK Proteins|Circadian Rhythm|Period Circadian Proteins|ARNTL Transcription Factors|Biological Clocks|Trans-Activators|Nuclear Proteins|Transcriptional Activation|Neuropeptide|RNA, Messenger|Gene Expression Regulation|timeless protein, Drosophila|vrille protein, Drosophila | |
10613896 J. Cell Biol. 1999 PMC2174238 EPS15 protein, human|*Adaptor Proteins, Signal Transducing|*Endocytosis|Phosphoproteins|Calcium-Binding Proteins|Intracellular Signaling Peptides and Proteins|Amino Acid Sequence|Protein Binding|Signal Transduction|Sequence Homology, Amino Acid|Domain, Protein-Protein Interaction|*Metabolic Networks and Pathways | |
10613898 J. Cell Biol. 1999 PMC2174245 *Myogenesis|*Cell Differentiation|Carrier Proteins|Integrin beta1|Cell Adhesion|Amino Acid Sequence|Integrins|Signal Transduction|Phosphorylation|Cell Line|Cytoplasm|Sequence Homology, Amino Acid|Muscle, Skeletal | |
10614670 Endocrinology 1999 IGFBP5 protein, human|*Insulin-Like Growth Factor Binding Protein 5|IGFBP3 protein, human|Insulin-Like Growth Factor Binding Protein 3|IGF2 protein, human|Insulin-Like Growth Factor II|IGF1 protein, human|Insulin-Like Growth Factor I|Carrier Proteins|Binding, Competitive|Electrophoresis, Polyacrylamide Gel|Insulin-Like Growth Factor Binding Protein 6|*Protein Domains | |
10615124 Nat. Genet. 1999 Mice|Animals|*Endoderm|Basic Helix-Loop-Helix Transcription Factors|Transcription Factors|Homeodomain Proteins|Helix-Loop-Helix Motifs|Cell Differentiation|Receptors, Notch|Repressor Proteins|Gene Expression Regulation, Developmental|Neurons|Signal Transduction|Membrane Proteins|Upregulation|Amino Acid Sequence|*Organogenesis|Pancreas | |
10615125 Nat. Genet. 1999 Polyostotic osteolytic dysplasia, hereditary expansile|*Peptide, Signal|*Osteolysis|Receptor Activator of Nuclear Factor-kappaB|Familial Paget's disease of bone|Osteitis Deformans|Osteoprotegerin|*Mutations|RANK Ligand|Glycoproteins|Nuclear Factor-Kappab|Osteoclast|Receptors, Cytoplasmic and Nuclear|Carrier Proteins|Membrane Glycoproteins|Exon|Mutant Proteins|Signal Transduction | |
10615129 Nat. Genet. 1999 Humans|*Pemphigus, Benign Familial|Darier Disease|*Mutations|Sarcoplasmic Reticulum Calcium-Transporting ATPases|Keratinocytes|Pedigree|Skin|Golgi Apparatus|Databases, Genetic|*Ion Transport|ATP2C1 protein, human|Calcium-Transporting ATPases | |
10617617 J. Biol. Chem. 2000 Humans|sphingosine 1-phosphate|*Lysophospholipids|*Sphingosine|*G-Protein-Coupled Receptors|*Signal Transduction|Receptors, Lysophospholipid|Receptors, Cell Surface|I-kappa B Proteins|Immediate-Early Proteins|NF-KappaB Inhibitor alpha|Mitogen-Activated Protein Kinases|Protein Kinase C|Serum Response Factor|Pertussis Toxin|Cell Division|*Cell Proliferation|Elk-1 Transcription Factor|Transfections | |
10617663 J. Biol. Chem. 2000 Humans|Animals|*Translocation, Genetic|RUNX1 Translocation Partner 1 Protein|*Leukemia, Myeloid, Acute|DNA-Binding Proteins|Core Binding Factor Alpha 2 Subunit|Repressor Proteins|Oncogene Proteins, Fusion|Transcription, Genetic|Proto-Oncogene Proteins|Nuclear Proteins|Histone Deacetylases|Nuclear Receptor Co-Repressor 1|Protein Binding|*Acute Disease|Promoter Regions, Genetic | |
10617778 Mol. Vis. 2000 Humans|Fundus Albipunctatus|retinol dehydrogenase|Night blindness, congenital stationary|*Night Blindness|Oguchi disease|*Eye Diseases, Hereditary|*Alcohol Oxidoreductases|*Genetic Diseases, X-Linked|*Myopia|*Mutations|DNA Mutational Analysis|Retinitis Pigmentosa|*Retinal Dystrophies|Electroretinography|Pedigree|interstitial retinol-binding protein|Eye Proteins|Fundus Oculi | |
10618369 Proc. Natl. Acad. Sci. U.S.A. 2000 PMC26614 Humans|*Ligands|FGFR2 protein, human|Receptor, Fibroblast Growth Factor, Type 2|Protein Conformation|Fibroblast Growth Factors|Signal Transduction|Receptor, Fibroblast Growth Factor, Type 1|Amino Acid Sequence|Models, Molecular|Crystallography, X-Ray|Binding Sites|Heparin | |
10618371 Proc. Natl. Acad. Sci. U.S.A. 2000 PMC26616 Saccharomyces cerevisiae|Saccharomyces cerevisiae Proteins|tRNA|*Sterols|Alkyl and Aryl Transferases|Mitochondria|Cell Nucleus|3,3-dimethylallyl pyrophosphate|Hemiterpenes|Cytosol|Mutation|Organophosphorus Compounds|MOD5 protein, S cerevisiae | |
10618429 Proc. Natl. Acad. Sci. U.S.A. 2000 PMC26674 Humans|*HIV-1|nef Gene Products, Human Immunodeficiency Virus|CD4-Positive T-Lymphocytes|NF-kappa B|DNA-Binding Proteins|Nuclear Proteins|Receptors, Antigen, T-Cell|Jurkat Cells|NFATC Transcription Factors|Lymphocyte Activation|CD28 Antigens|Signal Transduction|Cell Nucleus|Membrane Microdomains|nef protein, Human immunodeficiency virus 2|nef protein, Human immunodeficiency virus 1 | |
10618521 J. Immunol. Methods 2000 Humans|Animals|*Neutrophils|*Cytoplasmic Granules|*Proteins|Myeloperoxidase|Secretory Vesicles|Protein Processing, Post-Translational|Protein Transport|Organelles|Cell Line|Transfection|cDNA | |
10618718 Oncogene 2000 CRK protein, human|*Proto-Oncogene Proteins c-crk|GAB1 protein, human|*Adaptor Proteins, Signal Transducing|*Signal Transduction|src Homology Domain|Phosphorylation|Phosphoproteins|Mitogen-Activated Protein Kinases|c-jun N-Terminal Kinase|Proto-Oncogene Proteins c-met|JNK Pathway|Mitogen-Activated Protein Kinase 8 | |
10619026 Mol. Cell 2000 Humans|RHOA protein, human|*rhoA GTP-Binding Protein|Protein Structure, Tertiary|Protein Structure, Secondary|Protein Conformation|Protein Binding|Amino Acid Sequence|Binding Sites|Protein Kinase C|Models, Molecular|Crystallography, X-Ray|Signal Transduction|rho GTP-Binding Proteins|Guanosine 5'-O-(3-Thiotriphosphate) | |
10619433 Cell 2000 Animals|Hedgehog Proteins|*Signal Transduction|Drosophila Proteins|Drosophila|Body Patterning|*Cholesterol|Receptor, Patched|Membrane Proteins|*Biological Transport|Genes, Insect|Mutation | |
10620514 Biochem. J. 2000 PMC1220766 Humans|Rats|Animals|*Glutaminase|*Cloning, Molecular|Amino Acid Sequence|cDNA Library|Base Sequence|cDNA|Blotting, Northern|Escherichia coli|Sequence Homology, Amino Acid|Open Reading Frame|Liver|*Sequence Analyses | |
10620517 Biochem. J. 2000 PMC1220769 Humans|biliverdin reductase|*Kinetics|*Reductase|*Oxidoreductases Acting on CH-CH Group Donors|7,8-dimethylalloxazine|isoalloxazine|ferric citrate iron reductase|FMN Reductase|4,6-dinitro-o-cresol|NADPH|*Catalysis|Protein Binding|Oxidation-Reduction|Substrate Specificity|NADH, NADPH Oxidoreductases|mesobiliverdin|Biliverdin|Binding Sites | |
10620603 J. Exp. Med. 2000 PMC2195797 Humans|*HIV-1|*Mitochondrial Transmembrane Permeability-Driven Necrosis|mitochondrial permeability transition pore|*Mitochondrial Membrane Transport Proteins|BCL2 protein, human|Proto-Oncogene Proteins c-bcl-2|*Apoptosis|Mitochondria|Mitochondrial ADP, ATP Translocases|bcl-2-Associated X Protein|vpr Gene Products, Human Immunodeficiency Virus|Apoptosis Inducing Factor|Voltage-Dependent Anion Channels|Intracellular Membranes|Permeability | |
10622721 FEBS Lett. 2000 Cattle|Humans|Animals|*DNA, Complementary|prostaglandin-F synthase|*Hydroxyprostaglandin Dehydrogenases|Cloning, Molecular|PGH2|Amino Acid Sequence|Base Sequence|Dinoprost|mRNA|Lung|Substrate Specificity|Prostaglandin D2|Liver|Escherichia coli | |
10625600 J. Biol. Chem. 2000 *Ataxia Telangiectasia|*Proto-Oncogene Proteins c-abl|Cell Cycle Proteins|DNA Repair|Ataxia Telangiectasia Mutated Proteins|Tumor Suppressor Proteins|DNA Damage|DNA-Binding Proteins|Rad51 Recombinase|Nuclear Proteins|Recombination, Genetic|Phosphorylation|Ionizing Radiation|Chromosomal Aberrations|Genes, abl|Cell Line | |
10625641 J. Biol. Chem. 2000 Rats|Animals|Humans|*Iron|*Caco-2 Cells|*Biological Transport|*Cell Membrane|Iron-Binding Proteins|Cation Transport Proteins|Membrane Proteins|*Intestines|Cations, Divalent|Ion Transport|Enterocytes|Intestinal Absorption|Hydrogen-Ion Concentration | |
10625644 J. Biol. Chem. 2000 Humans|Mice|Animals|*Pulmonary Surfactant-Associated Protein A|HeLa Cells|NKX2-1 protein, human|Thyroid Transcription Factor 1|Nuclear Proteins|Transcription Factors|DNA-Binding Proteins|Promoter Regions, Genetic|Binding Sites|Transcription, Genetic|Pulmonary Surfactants|Regulatory Sequences, Nucleic Acid|Transcriptional Activation|Proteolipids|Base Sequence|Lung|Transfection|Cells, Epithelial | |
10625657 J. Biol. Chem. 2000 Humans|*Fructose-Bisphosphate Aldolase|Escherichia coli|Fructose Intolerance, Hereditary|Recombinant Proteins|fructose-1-phosphate|Fructosephosphates|*Catalysis|Kinetics|Cloning, Molecular|Mutagenesis, Site-Directed|Aldolases|Amino Acid Substitution|Amino Acid Sequence|Binding Sites|Mutation, Missense|Trioses | |
10625686 J. Biol. Chem. 2000 Rats|Animals|Cattle|*Clathrin-Coated Vesicles|*Cyclin|*Cyclin G|*G-Kinase|Clathrin|Coated Pits, Cell-Membrane|Auxilin|Adaptor Proteins, Vesicular Transport|HSC70 Heat-Shock Proteins|Endocytosis|*Biological Transport|HSP70 Heat-Shock Proteins|*Proliferating Cell Nuclear Antigen|Phosphoproteins|Protein Binding|Nerve Tissue Proteins|Protein-Serine-Threonine Kinases|Blotting, Western | |
10626794 Cancer Res. 2000 Humans|Mice|Animals|FGFR2 protein, human|*Receptor, Fibroblast Growth Factor, Type 2|*Messenger RNA|NIH 3T3 Cells|*Exons|Gene Amplification|Gastric Cancer|Tumor Cells, Cultured|*Homologous Recombination|Protein Tyrosine Kinase | |
10627461 Blood 2000 Cricetinae|Animals|Humans|*14-3-3 Proteins|CHO Cells|Cricetulus|adhesion receptor|*Platelet Glycoprotein GPIb-IX Complex|Platelet Adhesiveness|Platelet Activation|von Willebrand Factor|Platelets|Protein Binding|Platelet Glycoprotein GPIIb-IIIa Complex|Signal Transduction|Phosphorylation|Binding Sites|Protein Structure, Tertiary|Cytoskeleton|Cytoplasm|Ligands | |
10629050 Mol. Cell. Biol. 2000 PMC85210 Humans|*bcl-2-Associated X Protein|*Mitochondrial Membranes|BH3 Interacting Domain Death Agonist Protein|Proto-Oncogene Proteins c-bcl-2|Caspases|Mitochondria|Apoptosis|Carrier Proteins|Proto-Oncogene Proteins|HeLa Cells|Cytochrome c Group|Cytosol | |
10629055 Mol. Cell. Biol. 2000 PMC85215 *Fibroblast Growth Factor|*Signal Transduction|GRB2 protein, human|GRB2 Adaptor Protein|NGFR protein, human|*Receptors, Nerve Growth Factor|FGFR1 protein, human|Receptor, Fibroblast Growth Factor, Type 1|SH2 Domains|Phosphoproteins|Membrane Proteins|Phosphorylation|TYRP1 protein, human|*Membrane Glycoproteins|Nerve Tissue Proteins|Binding Sites|Protein Tyrosine Phosphatase, Non-Receptor Type 11|Protein Binding | |
10631139 Am. J. Hum. Genet. 2000 PMC1288352 Humans|Lysinuric Protein Intolerance|*Amino Acid Metabolism, Inborn Errors|*DNA Mutational Analysis|Intron|Fusion Regulatory Protein 1, Light Chains|Exons|Mutation|Alleles|Carrier Proteins|Amino Acid Transport Systems, Basic|Membrane Proteins|Homozygotes|Amino Acid Sequence|Amino Acids|Lysine|DNA|Italy|SLC7A7 protein, human | |
1063125 J. Biol. Chem. 1976 Humans|*Thymidine Kinase|*Isoenzymes|*Cytoplasm|*Mitochondria|*Cytosol|*Leukemia, Myeloid, Acute|Kinetics|Cations, Divalent|Molecular Weights|*Stem Cells|*Leukocytes|Magnesium | |
10631941 Immunol. Rev. 2000 Mice|Animals|*Antigen Presentation|invariant chain|*Histocompatibility Antigens Class II|Antigens, Differentiation, B-Lymphocyte|cathepsin S|endopeptidase B|Cathepsin L|Antigen Presenting Cells|Cathepsin B|tripeptide aminopeptidase|*Aminopeptidases|Lysosomes|Peptides|B Cells | |
10631952 Immunol. Rev. 2000 HLA-D Antigens|Antigens, Differentiation, B-Lymphocyte|Antigen Presentation|Peptides|Amino Acid Sequence|Protein Binding|*Membrane Proteins|Molecular Chaperones|Endosomes|Cell Membrane|B Cells|Lysosomes | |
10631978 Protein Sci. 2000 PMC2144227 Rats|Mice|Animals|metallothionein-1, mouse|*Metallothionein|*Nuclear Magnetic Resonance, Biomolecular|Protein Conformation|Magnetic Resonance Spectroscopy|Amino Acid Sequence|Cadmium|Models, Molecular|Protein Structure, Secondary|Cysteine|Isoforms|Metals|Brachyura | |
10631996 Protein Sci. 2000 PMC2144226 Humans|Sheep|Animals|*Aldehyde Dehydrogenase, Mitochondrial|*Solubility|Aldehyde Dehydrogenase|Amino Acid Sequence|*Liver|Mitochondria, Liver|Binding Sites|Kinetics|Cysteine|Mutagenesis, Site-Directed|NAD|Isozymes|Cytosol|*Chimera | |
10632589 J. Neurosci. 2000 PMC6772411 Humans|Mice|Animals|*Opsin|melanopsin|*Rod Opsins|*Retina|Retinal Ganglion Cells|In Situ Hybridization|Suprachiasmatic Nuclei|Pineal Gland|Amino Acid Sequence|Circadian Rhythms|Hypothalamus|Amacrine Cell | |
10637308 Mol. Biol. Cell 2000 PMC14774 *Hemidesmosomes|*Keratin|*Cytoskeletal Proteins|Dystonin|Non-Fibrillar Collagens|Bullous Pemphigoid|Autoantigens|*Membrane Proteins|*Cell Membrane|Carrier Proteins|Nerve Tissue Proteins|Collagen|Desmosomes|Recombinant Proteins|beta4 Integrin, alpha6|*Cytoskeleton|Intermediate Filaments | |
10637310 Mol. Biol. Cell 2000 PMC14776 *Saccharomyces cerevisiae|Saccharomyces cerevisiae Proteins|Golgi Complex|Vacuole|*Protein Sorting|Vesicular Transport Proteins|Membrane Proteins|*Yeast, Dried|Endosomes|Intracellular Membranes|Genes, Fungal|Carrier Proteins|Biological Transport|Receptors, Cell Surface|Amino Acid Sequence|Cloning, Molecular|Mutation | |
10637334 Nucleic Acids Res. 2000 PMC102560 Humans|*Saccharomyces cerevisiae|CNOT8 protein, human|Transcription Factors|Saccharomyces cerevisiae Proteins|Cell Cycle Proteins|Gene Expression Regulation, Fungal|*Yeast, Dried|Ribonucleases|Repressor Proteins|RNA Polymerase II|Protein Binding|Mutations|Phenotype|CCR4 protein, human|Receptors, CCR4|CCR4 protein, S cerevisiae|NOT5 protein, S cerevisiae | |
10639123 Proc. Natl. Acad. Sci. U.S.A. 2000 PMC15374 Humans|m-calpain|*Calcium|*Calpain|*Static Electricity|Protein Conformation|*Calcium, Dietary|Binding Site|Catalytic Domain|Models, Molecular|Amino Acid Sequence|Crystallography, X-Ray|Dimerization|Calmodulin|*Minerals | |
10639125 Proc. Natl. Acad. Sci. U.S.A. 2000 PMC15376 Azotobacter vinelandii|cysteine desulfurase|Carbon-Sulfur Lyases|Iron-Sulfur Proteins|Nitrogenase|Genes, Bacterial|Bacterial Proteins|Nitrogen Fixation|Amino Acid Sequence|Iron|Sulfur | |
10639137 Proc. Natl. Acad. Sci. U.S.A. 2000 PMC15388 Animals|Chlorocebus aethiops|Hereditary Multiple Exostoses|*Heparitin Sulfate|*Golgi Apparatus|N-Acetylglucosaminyltransferases|Proteins|Mutations|Cartilage|Glycosyltransferases|COS Cells|*Catalysis | |
10639150 Proc. Natl. Acad. Sci. U.S.A. 2000 PMC15401 *Interferon-gamma|*Lysosomes|TYRP1 protein, human|Oxidoreductases Acting on Sulfur Group Donors|Endosomes|Amino Acid Sequence|Antigen Processing|Disulfides|Antigen Presenting Cells|Cloning, Molecular|Proteolysis|Sulfhydryl Compounds|Catalysis|Cysteine|Active Site|Membrane Glycoproteins | |
10639334 J. Cell. Sci. 2000 Endothelial Cells|*Myosin II|Myosin Regulatory Light Chain|Myosin Light Chain Kinase|Cytoskeleton|Phosphorylation|Actins|rho-Associated Kinases|rhoA GTP-Binding Protein|Actin Cytoskeleton|Fibers, Stress|p21-Activated Kinases|Signal Transduction|*Cytoskeletal Proteins|Endothelium, Vascular|*B-Lymphocytes | |
10639434 Infect. Immun. 2000 PMC97193 Humans|Child|MBL2 protein, human|*Mannose-Binding Lectin|Mannose-Binding Protein-Associated Serine Proteases|Complement C4|Opsonin Proteins|Complement Activation|Collectins|Lectins|Staphylococcus aureus|Phagocytosis|Immunity, Innate|Carrier Proteins|Staphylococcal Infections|Protein Binding|Candida|Serine Endopeptidases | |
10640428 Exp. Cell Res. 2000 Humans|*Integrin alphaVbeta3|*Cell Adhesion|*Integrin-Binding Sialoprotein|Endothelial Cells|Receptors, Vitronectin|Cell Migration|Sialoglycoproteins|Wortmannin|Tumor Cells, Cultured|Endothelium, Vascular|Cells, Cultured|Neovascularization, Pathologic|Signal Transduction|Melanoma | |
10640743 J. Immunol. 2000 Leukocytes, Mononuclear|CC chemokine receptor 9|Receptors, CCR|CCL25 protein, human|*Chemokines, CC|*Chemokines|Chemotaxis|Lymphocyte Activation|Chemotaxis, Leukocyte|*Ligands|Signal Transduction|mRNA | |
10642496 Biochem. J. 2000 PMC1220772 STAT1 protein, human|STAT1 Transcription Factor|STAT3 protein, human|STAT3 Transcription Factor|Trans-Activators|Phosphorylation|Transcription, Genetic|*Cytoplasm|Cell Nucleus|TYRP1 protein, human|Dimerization|*Membrane Glycoproteins|Protein Binding|Signal Transduction|Transfection|src Homology Domains|Tyrosine | |
10642506 Biochem. J. 2000 PMC1220782 Humans|*Sarcosine Oxidase|pipecolic acid|L-pipecolate dehydrogenase|*Oxidoreductases Acting on CH-NH Group Donors|*Pipecolic Acids|Amino Acid Sequence|Sarcosine|cDNA|D-Amino-Acid Oxidase|Microbodies|Sequence Homology, Amino Acid|Bacillus|Open Reading Frame | |
10642508 Biochem. J. 2000 PMC1220784 Humans|Endosomal Sorting Complexes Required for Transport|Ligase, Ubiquitin-Protein|Nedd4 Ubiquitin Protein Ligases|*Sodium|Epithelial Sodium Channels|Binding Sites|Amino Acid Sequence|Calcium-Binding Proteins|Protein Binding|Tissues, Epithelial|Xenopus Proteins|Sequence Homology, Amino Acid|Downregulation | |
10642534 Biochem. J. 2000 PMC1220810 Animals|Humans|*Calcium|Drosophila melanogaster|*Mitochondria|citrin|Calcium-Binding Proteins|Mitochondrial Membrane Transport Proteins|Mitochondrial Proteins|Adult-onset citrullinemia type 2|Citrullinemia|Membrane Transport Proteins|Organic Anion Transporters|Protein Isoforms|Amino Acid Sequence|Glutamic Acid|*Heterozygote|Cell Line | |
10642597 J. Clin. Invest. 2000 PMC377427 Humans|dolichyl-phosphate beta-D-mannosyltransferase|*Congenital Disorders of Glycosylation|*Glycosylation|*Mannosyltransferases|*Mutations|Dolichol|Mannose|Oligosaccharides|Fibroblasts | |
10642602 J. Clin. Invest. 2000 PMC377434 Child|Humans|Mice|Animals|*Glycosylation|*Mannose|dolichyl-phosphate beta-D-mannosyltransferase|Mannosyltransferases|Congenital Disorders of Glycosylation|Mutations|Amino Acid Sequence|Seizures|Endoplasmic Reticulum|Dolichols|Phosphates | |
10643692 Int. J. Obes. Relat. Metab. Disord. 2000 Humans|*mRNA|*PPAR gamma|*Tissue Distribution|PPARGC1A protein, human|*Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha|Transcription Factors|Adipose Tissue|Obesity|Gene Expression|Nuclear Proteins|Insulin|Muscle, Skeletal|Diabetes Mellitus, Type 2|Cloning, Molecular | |
10644574 Am. J. Physiol. Gastrointest. Liver Physiol. 2000 Animals|Humans|Dogs|HEK293 Cells|*Organic Anion Transporters|*Hepatocyte|Sulfobromophthalein|Biological Transport|Liver|Organic Anion Transport Polypeptide C|Recombinant Proteins|Carrier Proteins|Cholyltaurine|*Cell Membrane|Amino Acid Sequence|Anion Transport Proteins|cDNA|Kidney|Transfections|17-glucuronosylestradiol|Estradiol | |
10644685 J. Biol. Chem. 2000 Humans|Proprotein Convertases|Serine Endopeptidases|Amino Acid Sequence|Sterol Regulatory Element Binding Protein 2|Substrate Specificity|Endoplasmic Reticulum|Protein Processing, Post-Translational|Proteolysis|Cell Lines|Sequence Homology, Amino Acid | |
10644686 J. Biol. Chem. 2000 Animals|Humans|*Methionine Adenosyltransferase|Escherichia coli|AdoMet|Cloning, Molecular|Amino Acid Sequence|Kinetics|cDNA|Catalysis | |
10644753 J. Biol. Chem. 2000 Humans|Chlorocebus aethiops|Animals|Mice|heparan sulfate 6-O-sulfotransferase|HS6ST2 protein, human|*Sulfotransferases|Heparitin Sulfate|cDNA|Amino Acid Sequence|Cloning, Molecular|cDNA Library|*Isoforms|Base Sequence|Blotting, Northern|Open Reading Frames|COS-7 Cells | |
10646116 J. Bone Miner. Res. 2000 *Microfibrils|*Latent TGF-beta Binding Proteins|Fibrillins|microfibrillar protein|Extracellular Matrix Proteins|Fibrillin-1|FN1 protein, human|Fibronectin|Contractile Proteins|Transforming Growth Factor beta|Microfilament Proteins|Carrier Proteins|TGFB1 protein, human|TGF-beta1|*Osteocytes|Fibroblasts|Intracellular Signaling Peptides and Proteins|Osteoblasts | |
10646523 J. Neurochem. 2000 Humans|*Charcot-Marie-Tooth Disease|HeLa Cells|connexin 32|*Connexins|Gap Junctions|Mutations|Point Mutations|Membrane Potentials|Genetic Linkage|Cell Communication|*Genetic Diseases, X-Linked|Schwann Cells|Phenotype|X Chromosome | |
10646604 Nature 2000 Humans|*KCNQ1 Potassium Channel|KCNQ Potassium Channels|Potassium|Amino Acid Sequence|Cyclic AMP|Intestinal Mucosa|Mutations|KCNE3 protein, human|Potassium Channels, Voltage-Gated|KCNQ1 protein, human | |
10647010 Nature 2000 Rats|Animals|*Aquaporins|*Anions|*Permeability|Aquaporin 6|Ions|*Cytoplasm|Water|Plasma Membranes|Xenopus laevis|Amino Acid Sequence|Oocytes|Mutagenesis, Site-Directed|Biological Transport|Models, Molecular|Hydrogen-Ion Concentration|TYRP1 protein, human|Membrane Glycoproteins | |
10648003 J. Leukoc. Biol. 2000 Humans|*Monocytes|CD163 antigen|*Antigens, Differentiation, Myelomonocytic|*Macrophages|*Receptors, Cell Surface|*Scavenger Receptor|*Antigens, CD|CSF1 protein, human|Colony-Stimulating Factor, Macrophage|sargramostim|Granulocyte-Macrophage Colony-Stimulating Factor|IL10 protein, human|Interleukin-10|*Anti-Inflammatory Agents|Lipopolysaccharides|IL4 protein, human|Interleukin-4|Tumor Necrosis Factor-alpha | |
10648173 Protein Expr. Purif. 2000 Humans|Protein-Tyrosine Kinases|Recombinant Proteins|Phosphorylation|Phosphotyrosine|Amino Acid Sequence|SH2 Domain|Syk Kinase|Intracellular Signaling Peptides and Proteins|Baculoviridae|Cloning, Molecular|Cell Line|Peptides|Gene Expression|Enzyme Precursors|Signal Transduction|Western Blotting|B Cells|Affinity Chromatography | |
10648410 Blood 2000 Humans|CD100 antigen|*Antigens, CD|*Semaphorin|ADP-ribosyl Cyclase|*Lymphocyte Activation|ADP-ribosyl Cyclase 1|B-Lymphocytes|*Protein Tyrosine Phosphatase|Antigens, Differentiation|Membrane Glycoproteins|PTPRC protein, human|Leukocyte Common Antigens|Signal Transduction|*Hematopoiesis|Cell Lines|Palatine Tonsil|NAD+ Nucleosidase|Phosphorylation | |
10648629 Mol. Cell. Biol. 2000 PMC85307 *Phosphatidylinositol 3-Kinase|GAB1 protein, human|*Adaptor Proteins, Signal Transducing|*Signal Transduction|Phosphorylation|Mitogen-Activated Protein Kinases|Phosphoproteins|Phosphatidylinositol 3-Kinases|Proto-Oncogene Proteins c-akt|EGFR protein, human|Epidermal Growth Factor Receptor|PTEN protein, human|Phosphatase, PTEN|src Homology Domains|Enzyme Activation|Protein Tyrosine Phosphatase, Non-Receptor Type 11|Tyrosine | |
10648798 Nucleic Acids Res. 2000 PMC102581 Humans|Female|Pregnancy|Cell Line, Tumor|Transcription Factors|*Chorionic Gonadotropin|8-chloro-cyclic adenosine monophosphate|*8-Bromo Cyclic Adenosine Monophosphate|Binding Sites|Promoter Regions, Genetic|Chorionic Gonadotropin, beta Subunit, Human|Placenta|Glycoprotein Hormones, alpha Subunit|Base Sequence|Transcription Factor AP-2|Amino Acid Sequence|Cyclic AMP | |
10649434 J. Cell. Biochem. 2000 Humans|*G(s)alpha|Guanosine Diphosphate|GTPgammaS|Guanosine Triphosphate|*Mutagenesis|Cyclase, Adenylyl|GTPase|Protein Binding|Kinetics|Binding Sites|Models, Molecular|Signal Transduction|Hydrolysis | |
10651831 Eur. J. Biochem. 2000 Chlorocebus aethiops|Humans|Mice|Animals|Escherichia coli|Receptors, Immunologic|Macrophages|oxidized low density lipoprotein|Lipoproteins, LDL|Scavenger Receptors, Class B|Amino Acid Sequence|cDNA Library|Cloning, Molecular|Protein Binding|COS Cells|DNA, Complementary|acetyl-LDL|Ligands|Carrier Proteins|Staphylococcus aureus|Marco protein, mouse | |
10652231 Biochem. Biophys. Res. Commun. 2000 Mice|Animals|*ARNTL Transcription Factors|*mRNA|*Suprachiasmatic Nucleus|CLOCK Protein|Period Circadian Proteins|Trans-Activators|Nuclear Proteins|Circadian Rhythm|Cell Cycle Proteins|Gene Expression Regulation|In Situ Hybridization|Blotting, Northern|Liver | |
10652252 J. Cell. Sci. 2000 Humans|*Secretory Pathway|Golgi Apparatus|Endoplasmic Reticulum|Carrier Proteins|Mannose-Specific Lectin|Membrane Proteins|Protein Transport|Glycoproteins|HeLa Cells | |
10652257 J. Cell. Sci. 2000 Animals|Swine|*Phospholipase D|*Phosphoinositide 3 Kinase|*Phosphatidylinositol 3-Kinases|*Tyrosine|*Endothelial Cells|FGFR1 protein, human|*Fibroblast Growth Factor Receptor 1|Phosphorylation|Signal Transduction|Mitogen-Activated Protein Kinases|*Phospholipases A2|Phospholipase C gamma|*Aorta|Isoenzymes|Cell Division | |
10652259 J. Cell. Sci. 2000 Humans|Male|Mice|Animals|*Bloom Syndrome|Bloom syndrome protein|*Meiosis|*RecQ Helicases|*Prophase|Rad51 Recombinase|DNA Replication|*Mitosis|*Cell Nucleus|*Chromosome Stability|DNA-Binding Proteins|Sister Chromatid Exchange|Recombination, Genetic|Saccharomyces cerevisiae|*Protein Stability|Cell Line|Western Blots|Protein Binding | |
10652308 J. Biol. Chem. 2000 Humans|*ADP-Ribosylation Factors|cytohesin-1|*Guanine Nucleotide Exchange Factors|EEF1D protein, human|*Peptide Elongation Factor 1|ADP-Ribosylation Factor 1|Brefeldin A|Amino Acid Sequence|GTP-Binding Proteins|Guanosine 5'-O-(3-Thiotriphosphate)|Guanosine Diphosphate|Cloning, Molecular|Protein Binding|Fungal Proteins|Sequence Homology, Amino Acid|cDNA Library | |
10652316 J. Biol. Chem. 2000 EPS15 protein, human|*Adaptor Proteins, Signal Transducing|Clathrin|Phosphoproteins|Coated Pits, Cell-Membrane|Endocytosis|Intracellular Signaling Peptides and Proteins|Calcium-Binding Proteins|Adaptor Proteins, Vesicular Transport|Membrane Proteins|Adaptor Protein Complex alpha Subunits|Signal Transduction|Plasma Membrane|Protein Binding|Transferrin | |
10652353 J. Biol. Chem. 2000 Chlorocebus aethiops|Animals|*rho-Associated Kinases|*Phosphorylation|LIMK1 protein, human|*Lim Kinases|*Threonine|Actin|Microfilament Proteins|Actin Depolymerizing Factors|Protein Kinases|Cytoskeleton|COS Cells|Actin Cytoskeleton|Actin Depolymerizing Factor|Signal Transduction|DNA-Binding Proteins|GTPase | |
10652516 Trends Cell Biol. 2000 *Guanine Nucleotide Exchange Factors|ADP-Ribosylation Factor 1|Brefeldin A|ADP-Ribosylation Factors|GTP-Binding Proteins|Amino Acid Sequence|Fungal Proteins|Sequence Homology, Amino Acid|Protein Transport|Nucleotides|Guanine | |
10654609 Development 2000 Proteins, Homeo Domain|Transcription Factors|Enhancer Elements, Genetic|Pre-B-Cell Leukemia Transcription Factor 1|Rhombencephalon|Hox Genes|Gene Expression Regulation, Developmental|Binding Sites|Base Sequence|Transcription, Genetic | |
10655068 Nat. Genet. 2000 Humans|Adult|Child|alpha-methylacyl-CoA racemase|*Racemases and Epimerases|*Mutations|Peroxisomes|pristanic acid|Acids, Fatty|Amino Acid Sequence|Bile Acids and Salts|Disease, Refsum|CoA, Acyl|Cloning, Molecular|Liver | |
10655230 Genetics 2000 PMC1460965 Mice|Animals|*Eukaryotic Initiation Factor-2|*Phosphorylation|Saccharomyces cerevisiae|Saccharomyces cerevisiae Proteins|Protein-Serine-Threonine Kinases|eIF-2alpha Kinase|Histidyl-tRNA Synthetase|tRNA|DNA-Binding Proteins|Protein Biosynthesis|mRNA|Amino Acid Sequence|Cloning, Molecular|Sequence Homology, Amino Acid|*Mammals|Amino Acids|GCN2 protein, S cerevisiae | |
10655614 Nat. Struct. Biol. 2000 *rhoGDI|Guanine Nucleotide Dissociation Inhibitors|Protein Conformation|Protein Binding|Binding Site|rho Guanine Nucleotide Dissociation Inhibitor alpha|Guanosine Diphosphate|Amino Acid Sequence|Models, Molecular|RHOA protein, human|rhoA GTP-Binding Protein|rho GTP-Binding Proteins|Transfection|rac1 GTP-Binding Protein|Cytosol | |
10656257 Mol. Cell. Neurosci. 2000 *Myelin Sheath|*Schwann Cells|enhancer-binding protein AP-3|Transcription Factors|*Gene Expression Regulation|Helix-Loop-Helix Motifs|Cell Differentiation|Myelin P0 Protein|Repressor Proteins|Basic Helix-Loop-Helix Transcription Factors|Gene Expression|Inhibitor of Differentiation Protein 1|Cells, Cultured|Sciatic Nerves|Promoter Regions, Genetic|Axons|RNA, Messenger | |
10656791 J. Mol. Biol. 2000 *Replication Protein C|*Proliferating Cell Nuclear Antigen|*DNA Polymerase I|*B-DNA|*DNA Replication|DNA Polymerase III|DNA-Directed DNA Polymerase|Primase|Homeodomain Proteins|Saccharomyces cerevisiae Proteins|Repressor Proteins|DNA|Minor Histocompatibility Antigens | |
10656792 J. Mol. Biol. 2000 *Replication Protein C|DNA polymerase alpha-primase|*DNA Polymerase I|*B-DNA|*DNA Replication|DNA Polymerase delta|DNA Primase|Proliferating Cell Nuclear Antigen|Homeodomain Proteins|Repressor Proteins|Saccharomyces cerevisiae Proteins|Minor Histocompatibility Antigens|Protein Binding|DNA|DNA Primers|Kinetics|*Nucleotidyltransferases|Proto-Oncogene Proteins c-bcl-2 | |
10656833 J. Mol. Biol. 2000 Animals|Humans|*Catalase|*NADP|*Catalysis|Hydrogen Bonding|*Ligands|Binding Site|Protein Conformation|Crystallography, X-Ray|Amino Acid Sequence|Models, Molecular|Redox|tyrosine radical|Tyrosine|Haem|Substrate Specificity|Active Site|Arginine | |
10658666 Microbiology (Reading, Engl.) 2000 *Trehalose|Mycobacterium smegmatis|Mycobacterium tuberculosis|Glycogen|Maltose|Disaccharides|Glucosyltransferases|Cell Wall|Glycolipids|Glucose-6-Phosphate|*Carbohydrate Metabolism | |
10659855 Nature 2000 eukaryotic initiation factor-5B|*Eukaryotes|eIF-4B|*Eukaryotic Initiation Factors|EIF1 protein, human|RNA, Transfer, Initiator|*Subunits, Ribosomal|Eukaryotic Initiation Factor-5|Ribosome|Initiation Codon|Peptide Chain Initiation, Translational|Eukaryotic Initiation Factor 3|Eukaryotic Initiation Factor-1|EIF-2|Guanosine Triphosphate|Messenger RNA|Hydrolysis|Neoplasm Proteins | |
10660298 Curr. Biol. 2000 Animals|*Active Transport, Cell Nucleus|*Cactus|Transcription Factors|Drosophila|Drosophila Proteins|DNA-Binding Proteins|Drosophila melanogaster|Nuclear Proteins|Phosphoproteins|Cell Nucleus|Toll-Like Receptors|Phosphorylation|Receptors, Cell Surface|Signal Transduction|Protein-Serine-Threonine Kinases|Membrane Glycoproteins|Cytoplasm | |
10660545 J. Biol. Chem. 2000 Cats|Animals|G-T mismatch-binding protein|*DNA-Binding Proteins|DNA Repair|ATPase|MutS Homolog 2 Protein|MutS Homolog 3 Protein|Base Pair Mismatch|Adenosine Diphosphate|DNA|Substrate Specificity|Adenosine Triphosphate|Protein Binding|Proto-Oncogene Proteins|Binding Sites|Kinetics|Hydrolysis | |
10660610 J. Biol. Chem. 2000 Humans|*Catalytic Domain|*M Phase Cell Cycle Checkpoints|Saccharomyces cerevisiae|MAD2L2 protein, human|*Mad2 Proteins|DNA polymerase zeta|DNA-Directed DNA Polymerase|DNA Repair|DNA-Binding Proteins|Nuclear Proteins|DNA Damage|Amino Acid Sequence|Mutagenesis|Sequence Homology, Amino Acid | |
10660611 J. Biol. Chem. 2000 *Receptors, Erythropoietin|*Inositol Polyphosphate 5-Phosphatases|GRB2 protein, human|GRB2 Adaptor Protein|Phosphorylation|Signal Transduction Pathways|AKT1 protein, human|Protein Kinase B|EPO protein, human|Erythropoietin|src Homology Domains|INPP5D protein, human|*Phosphatidylinositol-3,4,5-Trisphosphate 5-Phosphatases|Shc Signaling Adaptor Proteins|Adaptor Proteins, Vesicular Transport|Phosphotyrosine|Tyrosine|Phosphoric Monoester Hydrolases | |
10660625 J. Biol. Chem. 2000 Animals|Humans|Female|Pregnancy|*Multispecific Organic Anion Transporter|Organic Anion Transporters, Sodium-Independent|estrone sulfate|Estrone|*Cloning, Molecular|*Placenta|Organic Anion Transporters|cDNA|Biological Transport|cDNA Library|Xenopus laevis|mRNA|Blotting, Northern|Kidney|estradiol sulfate|Estradiol|Amino Acid Sequence|ochratoxin A | |
10662833 J. Neurosci. 2000 PMC6772386 Animals|Humans|potassium-dependent sodium-calcium exchanger|*Retinal Cone Photoreceptor Cells|*Chickens|sodium-calcium exchanger 1|*Sodium-Calcium Exchanger|Rod Outer Segment|*Cloning, Molecular|Potassium|Sodium|Calcium|Amino Acid Sequence|Carrier Proteins|cDNA|Plasma Membrane|Cell Line|Ions | |
10666321 Arch. Biochem. Biophys. 2000 Humans|Rats|Animals|*Squalene Monooxygenase|Kinetics|Reductase, NADPH-Cytochrome P450|tellurous acid|Tellurium|Oxygenases|POR protein, human|Cytochrome P-450 Enzyme System|Flavin-Adenine Dinucleotide|tellurium dioxide|NADP|Escherichia coli|Flavins|Compounds, Selenium|Cloning, Molecular | |
1066663 Proc. Natl. Acad. Sci. U.S.A. 1976 PMC430686 Humans|*Factor XII|*Kininogen, High-Molecular-Weight|kininogen 1, human|*Kininogens|Prekallikrein|Kallikrein|Blood Coagulation|Factor XIIa|Protein Binding|Binding Sites|Factor XIa|Kaolin|Molecular Weight | |
10667208 Ann. N. Y. Acad. Sci. 2000 Mice|Humans|Rats|Animals|*Cell Proliferation|Cell Transformation, Neoplastic|Apoptosis|Genes, ras|*Cell Cycle|ras Proteins|Cell Division|*Fatty Acids|Signal Transduction|UM 96001|Palmitic Acids|3T3 Cells|*Ketones | |
10668806 RNA 2000 PMC1369901 Humans|*Nuclear Pore|HeLa Cells|Nucleoporin|Nucleocytoplasmic Transport Proteins|messenger ribonucleoprotein|Ribonucleoproteins|*RNA Transport|Transportin|Cell Nucleus|Transport, Nuclear|Saccharomyces cerevisiae|Saccharomyces cerevisiae Proteins|Nuclear Proteins|Messenger RNA|RNA-Binding Proteins|Cytoplasm|Receptors, Nuclear|Binding Sites | |
10669743 Mol. Cell. Biol. 2000 PMC85349 Humans|*Telomere|TTAGGG Repeat Binding Factor 1|TERF1 protein, human|Telomeric Repeat Binding Protein 2|Telomerase|Telomere Homeostasis|DNA-Binding Proteins|HeLa Cells | |
10669757 Mol. Cell. Biol. 2000 PMC85363 Humans|Mice|Animals|*Notch Receptors|HeLa Cells|Membrane Proteins|*Dimerization|Ligands|Signal Transduction|Receptor, Notch2|Protein Binding|NIH 3T3 Cells|Transcription Factors|Intracellular Signaling Peptides and Proteins|Drosophila|Drosophila Proteins|Cell Membrane|notch protein, Drosophila | |
10671541 J. Biol. Chem. 2000 Rats|Animals|*Perilipin|*Sterol Esterase|*Lipolysis|*Adipocytes|Phosphorylation|Isoproterenol|Lipid Droplet|Phosphoproteins|Carrier Proteins|beta-Adrenergic Agonist|Protein Transport|Cytosol|Catecholamines|*Translocation, Genetic | |
10671560 J. Biol. Chem. 2000 Humans|SLP-76 signal Transducing adaptor proteins|*Phosphoproteins|*Adaptor Proteins, Signal Transducing|T-Cell Antigen Receptor|Nuclear Proteins|DNA-Binding Proteins|SH2 Domain|Signal Transduction|Phosphorylation|Jurkat Cells|Protein-Tyrosine Kinases|Phospholipase C gamma 1|NFATC Transcription Factors|Carrier Proteins|Membrane Proteins|Interleukine 2|Binding Sites|Promoter Regions, Genetic | |
10671563 J. Biol. Chem. 2000 *Heme b|*Eukaryotic Initiation Factor 2alpha Kinase|Phosphorylation|Hemin|Protein Binding|Reticulocytes|Binding Sites|Mutagenesis, Site-Directed|Protein Biosynthesis|Peptide Initiation Factors | |
10672018 Eur. J. Biochem. 2000 Humans|*Kynurenine 3-Monooxygenase|Kinetics|NADPH|Flavin-Adenine Dinucleotide|Mixed Function Oxygenases|Oxidation-Reduction|Flavins|NAD|Hydroxylation|Oxygenases|Substrate Specificity|3-hydroxykynurenine|Kynurenine|Catalysis|Recombinant Proteins | |
10673326 Mol. Cell. Neurosci. 2000 *Alzheimer Disease|*Agrin|amyloid beta-protein (1-40)|Amyloid beta-Peptides|Senile Plaques|Peptide Fragments|*Brain|Heparan Sulfate Proteoglycan|Heparitin Sulfate|Immunohistochemistry | |
10673331 Genomics 2000 Humans|*Chondrodysplasia Punctata, Rhizomelic|*Alleles|*Haplotypes|Pex7p|Homozygotes|Peroxisome biogenesis disorders|Peroxisomal Disorders|Founder Effect|Mutation|Amino Acid Sequence|cDNA|Peroxisomes|Receptors, Cytoplasmic and Nuclear | |
10673366 Biochem. Biophys. Res. Commun. 2000 *Osteopontin|*beta-1, Integrin alpha-5|Integrins|Cell Adhesion|arginyl-glycyl-aspartic acid|Oligopeptides|Amino Acid Sequence|Cell Line|Thrombin | |
10673423 Structure 2000 Animals|Humans|*NADP|*Protons|*Mitochondria, Heart|*NADP Transhydrogenases|NADH|Binding Site|*Hydrogen|Protein Conformation|Protein Binding|Rhodospirillum rubrum|Proton Pump|Models, Molecular|Kinetics|*Biochemical Phenomena|*Biophysical Phenomena | |
10673500 Genes Dev. 2000 PMC316357 Humans|*Tumor Suppressor Protein p53|CHEK2 protein, human|*Checkpoint Kinase 2|MDM2 protein, human|Proto-Oncogene Proteins c-mdm2|Phosphorylation|DNA Damage|Cell Cycle Proteins|Ataxia Telangiectasia Mutated Proteins|Protein Kinases|Tumor Suppressor Proteins|DNA-Binding Proteins|Nuclear Proteins|Schizosaccharomyces pombe|*Cell Cycle Arrest | |
10673501 Genes Dev. 2000 PMC316358 Humans|*Phosphorylation|*Tumor Suppressor Protein p53|CHEK1 protein, human|*Chk1 Kinase|CHEK2 protein, human|Checkpoint Kinase 2|*DNA Damage|Protein Kinase|Cell Cycle Proteins|Schizosaccharomyces pombe Proteins|Schizosaccharomyces pombe|Protein Processing, Post-Translational | |
10675331 EMBO J. 2000 PMC305600 *Substrate Specificity|*GTPase|*Signal Transduction|*Tyrosine Kinase|STAT3 protein, human|STAT3 Transcription Factor|Phosphorylation|Receptors, Epidermal Growth Factor|Epidermal Growth Factor|DNA-Binding Proteins|Phosphotyrosine|Trans-Activators|Proto-Oncogene Proteins pp60(c-src)|Transfection|Tyrosine | |
1067618 Proc. Natl. Acad. Sci. U.S.A. 1976 PMC431003 Humans|Animals|Rabbits|Iodine-125|*Iodine Radioisotopes|Properdin|*Complement Factor H|Complement C3b Inactivator Proteins|C3 Convertase|Complement C3|Complement Activation|Erythrocyte|Inactivator, C3b|C3 Nephritic Factor | |
10676816 Cell 2000 *rhoGDI|*cdc42 GTP-Binding Protein|GDIs|Guanosine Diphosphate|Amino Acid Sequence|Protein Conformation|Protein Binding|Guanosine Triphosphate|Binding Sites|rho GTP-Binding Proteins|X Ray Crystallographies|rho Guanine Nucleotide Dissociation Inhibitor alpha|Sequence Alignment|Models, Molecular|Sequence Homology, Amino Acid | |
10676844 Cell. Signal. 2000 STAT5A protein, human|*STAT5 Transcription Factor|EPO protein, human|*Erythropoietin|Receptors, Erythropoietin|*Tumor Suppressor Proteins|Transductions, Signal|Trans-Activators|DNA-Binding Proteins|Janus Kinase 2|Phosphorylation|Erythroleukemia|*Apoptosis|Protein Binding|Tyrosine|Cell Lines | |
10676964 Nature 2000 Kv Channel-Interacting Proteins|Shal Potassium Channels|Calcium-Binding Proteins|Membrane Potentials|Neurons|*Calcium, Dietary|Amino Acid Sequence|Protein Subunits|Potassium|Kinetics|Transfection | |
10676965 Nature 2000 Mice|Animals|*GTPase|Transducin|Rod Outer Segments|Regulators of G Protein Signaling Proteins|Heterotrimeric G-Proteins|Cyclic Nucleotide Phosphodiesterases, Type 6|3',5'-Cyclic-GMP Phosphodiesterases|Retina|Kinetics|Hydrolysis | |
10677367 Biochem. J. 2000 PMC1220874 Animals|Mice|Humans|heparan sulfate L-iduronyl 2-O-sulfotransferase|*Sulfotransferases|Heparitin Sulfate|Iduronic Acid|Glucuronic Acid|heparin, O-desulfated|Heparin|glucuronic acid 2-sulfate|Glucuronates|*Kidney|Carbohydrate Epimerases|Glucosamine|Disaccharides|*Epithelial Cells | |
10677481 Proc. Natl. Acad. Sci. U.S.A. 2000 PMC26453 Humans|Animals|*Acetyl-CoA Carboxylase|Malonyl CoA|Amino Acid Sequence|Isoenzymes|Kinetics|Oxidation-Reduction|RNA, Messenger | |
10677529 Proc. Natl. Acad. Sci. U.S.A. 2000 PMC26507 Chick Embryo|Animals|*Vascular Endothelial Growth Factor A|*Endothelial Cells|Chicken|*Vascular Endothelial Growth Factors|*Signal Transduction|Phosphatidylinositol 3-Kinases|Proto-Oncogene Proteins c-akt|Phosphorylation|Proto-Oncogene Proteins|Phosphatidylinositol 3-Kinase|mRNA | |
10677542 Proc. Natl. Acad. Sci. U.S.A. 2000 PMC26522 Animals|Rats|*Saccharomyces cerevisiae|choline transporter|*Membrane Transport Proteins|*Yeast, Dried|Choline|Carrier Proteins|Acetylcholine|*Mutation|Amino Acid Sequence|Biological Transport|In Situ Hybridization|Caenorhabditis elegans|Neurons|Cloning, Molecular|RNA, Messenger|Brain|Sequence Homology, Amino Acid|Spinal Cord | |
10678165 Mol. Cell 2000 Mice|Animals|*src Tyrosine Kinases|Diap1 protein, mouse|DIAPH3 protein, human|*Formins|*Signal Transduction|ROCK1 protein, human|rho-Kinase|Fetal Proteins|Actin|Nuclear Proteins|Carrier Proteins|Fibers, Stress|Microfilament Proteins|Protein Binding|Serum Response Factor|Cytoskeleton|rho GTP-Binding Proteins|3T3 Cells | |
10678170 Mol. Cell 2000 Humans|Male|Mice|Animals|*Synaptonemal Complex|Meiosis|*Synapsis, Chromosomal|Sycp3 protein, mouse|Nuclear Proteins|Spermatocytes|SYCP1 protein, human|Spermatogenesis|DNA-Binding Proteins|Infertility, Male|Testis|Recombination, Genetic|Apoptosis|Fertility | |
10679020 Mol. Biol. Cell 2000 PMC14799 *Golgi Apparatus|macrogolgin|Golgi Matrix Proteins|Vesicular Transport Proteins|Membrane Proteins|Carrier Proteins|COPI-Coated Vesicles|Autoantigens|Protein Binding|Amino Acid Sequence|Mitosis|Biological Transport|Phosphorylation | |
10679061 J. Immunol. 2000 Humans|*Mannose-Binding Protein-Associated Serine Proteases|ficolin|*Lectins|*Complement Activations|MBL2 protein, human|Mannose-Binding Lectin|Collectins|Complement C4|Carrier Proteins|Serine Endopeptidases|Protein Binding|*Immunologic Factors|Immunity, Innate | |
10679223 Biochem. Biophys. Res. Commun. 2000 Animals|Humans|In Situ Hybridization, Fluorescence|PAPS synthetase|Sulfate Adenylyltransferase|Multienzyme Complexes|*Cloning, Molecular|Sulfotransferases|DNA Primers|Exons|Intron|cDNA|Hominidae|*Biological Phenomena|*Physiological Phenomena|Blotting, Northern|Ligases | |
10679238 Biochem. Biophys. Res. Commun. 2000 Animals|Humans|United States|*Cyclin A|CDK2 protein, human|*Cyclin-Dependent Kinase 2|*Cell Cycle Proteins|*Phosphorylation|Cyclin-Dependent Kinases|CDC2-CDC28 Kinases|Cyclin|S Phase|Cell Cycle|Anaphase-Promoting Complex-Cyclosome|Anaphase|Phases, G2|Proliferating Cell Nuclear Antigen|Transcription Factors|Centers for Disease Control and Prevention, U.S.|CDC20 protein, human|Cdc20 Proteins | |
10679268 Biochem. Biophys. Res. Commun. 2000 Mice|Animals|*src Homology Domains|STAP1 protein, human|*Adaptor Proteins, Signal Transducing|Hematopoietic Stem Cells|*Cloning, Molecular|TAL1 protein, human|*T-Cell Acute Lymphocytic Leukemia Protein 1|Proto-Oncogene Proteins c-kit|Bone Marrow Cells|Cell Differentiation|Hematopoiesis|Phosphorylation|LIF protein, human|Inhibitory Factor, Leukemia|Amino Acid Sequence|Receptor Protein-Tyrosine Kinases|Protein Binding | |
10679438 Curr. Opin. Neurobiol. 2000 Animals|plexin|Nerve Tissue Proteins|*Carrier Proteins|Semaphorin-3A|Neuropilin-1|Glycoproteins|Semaphorins|Axons|*Vertebrates|Cell Adhesion Molecules|Receptors, Cell Surface|*Invertebrates|Signal Transduction | |
10679930 Dev. Dyn. 2000 Mice|Animals|*Retinoic Acid|HOXA5 protein, human|Homeodomain Proteins|Hox Genes|Transcription Factors|Gene Expression Regulation, Developmental|TGFB1 protein, human|*TGF-beta1|Phosphoproteins|Mesenchyme|In Situ Hybridization | |
10679936 Hum. Mutat. 2000 Child|Humans|Male|Female|*Pyruvate Dehydrogenase Complex Deficiency Disease|pyruvate dehydrogenase E1alpha subunit|*Pyruvate Dehydrogenase (Lipoamide)|Pyruvate Dehydrogenase Complex|*Mutations|*X-Linked Gene|Exons|X Chromosome|Codons|Mutations, Missense|Mutations, Insertion-Deletion|Pyruvates | |
10681516 J. Biol. Chem. 2000 Humans|Animals|Mice|*DNA, Complementary|5'(3')-nucleotidase|*Escherichia coli|5'-Nucleotidase|Cloning, Molecular|Sequences, Amino Acid|Base Sequence|Recombinant Proteins|Polymerase Chain Reaction|*Mammals|Substrate Specificity|Transfections|DNA|Sequence Homology, Amino Acid | |
10681536 J. Biol. Chem. 2000 Humans|Mice|Animals|Rats|zinc-binding protein|Zinc|Biological Transport|Cation Transport Proteins|Plasma Membrane|Transfections|Amino Acid Sequence|Metals|Ions|Sequence Homology, Amino Acid|Kinetics|K562 Cells | |
10681547 J. Biol. Chem. 2000 Rats|Swine|Animals|CD39 antigen|*Apyrase|Antigens, CD|*Liver|ATPases|Amino Acid Sequence|Hepatocytes|Kinetics|Tissue Distribution|Immunohistochemistry|Sodium Azide|*Biochemical Phenomena|Molecular Weight|Kidney|Immunoblotting|Endothelium, Vascular | |
10681567 J. Biol. Chem. 2000 Mice|Animals|Humans|*sPLA(2)|Cloning, Molecular|Recombinant Proteins|Arachidonic Acid|Amino Acid Sequence|Substrate Specificity|Phospholipids|In Situ Hybridization|Sequence Homology, Amino Acid|Exon | |
10681634 Horm. Res. 2000 Child|Adolescent|Male|Humans|Female|Infant|Child, Preschool|IGFBP3 protein, human|*Insulin-Like Growth Factor Binding Protein 3|IGF2 protein, human|*Insulin-Like Growth Factor II|IGF1 protein, human|*Insulin-Like Growth Factor I|IGFBP1 protein, human|Insulin-Like Growth Factor Binding Protein 1|Insulin-Like Growth Factor Binding Protein 2|IGFBP|Human Growth Hormone|Growth Hormone|*Endocrine System Diseases|Reference Values | |
10684251 J. Cell Biol. 2000 PMC2169372 Animals|*Xenopus laevis|*Axin Protein|*Glycogen Synthase Kinase 3|CTNNB1 protein, human|beta Catenin|Wnt Proteins|Binding Protein|Xenopus Proteins|Trans-Activators|Repressor Proteins|Phosphorylation|Signal Transduction|Adenomatous Polyposis Coli Protein|Adaptor Proteins, Signal Transducing|Calcium-Calmodulin-Dependent Protein Kinases|*Adenomatous Polyposis Coli|Phosphoproteins|Zebrafish Proteins | |
10684856 J. Exp. Med. 2000 PMC2195830 B cell linker protein|*Phospholipase C gamma2|*Receptors, Antigen, B-Cell|*Adaptor Proteins, Signal Transducing|*Carrier Proteins|Phosphoproteins|B Cells|Signal Transduction|*Lymphocyte Activation|src Homology Domains|Phosphorylation|Protein-Tyrosine Kinases|Intracellular Signaling Peptides and Proteins|Syk Kinase|Isoenzymes | |
10684876 J. Neurosci. 2000 PMC6772911 Animals|Drosophila melanogaster|CLOCK Proteins|Drosophila melanogaster Proteins|*Gene Expression Regulation|Period Circadian Proteins|ARNTL Transcription Factors|Drosophila|Trans-Activators|Transcription, Genetic|Nuclear Proteins|Circadian Rhythm|Helix-Loop-Helix Motifs|RNA, Messenger|timeless protein, Drosophila | |
10684912 N. Engl. J. Med. 2000 SLC6A2 protein, human|*Transporter, Norepinephrine|*Orthostatic Intolerance|*Tachycardia|dopamine beta hydroxylase deficiency|*Norepinephrine|*Autonomic Nervous System Diseases|*Dopamine beta-Hydroxylase|Syncope|Heart Rate|Lightheadedness|Blood Pressure|*Membrane Transport Proteins|Posture | |
10684930 Nucleic Acids Res. 2000 PMC111038 Humans|isoguanine|*Guanine|*Cell Nucleus|DNA Glycosylases|DNA-Formamidopyrimidine Glycosylase|*DNA|*Mitochondria|Base Pair Mismatch|DNA Repair|Adenine|Escherichia coli Proteins|Escherichia coli|Protein Binding|Western Blotting|Sequence Homology, Amino Acid|Amino Acid Sequence | |
10684970 Biochim. Biophys. Acta 2000 Humans|Escherichia coli|LARS2 protein, human|*Amino Acyl-tRNA Synthetases|Leucine-tRNA Ligase|Aminoacylation|Aminoacylations, tRNA|Amino Acid Sequence|tRNA(Leu)|Amino Acids|Cloning, Molecular|Mitochondria|Adenosine Triphosphate|Saccharomyces cerevisiae|Bacterial Proteins | |
10686426 Matrix Biol. 2000 Mice|Animals|*Collagen Type I|*Scavenger Receptors|*Macrophages|Receptors, Immunologic|Integrins|Cell Adhesion|Cell Adhesion Molecules|Collagen|Amino Acid Sequence|arginyl-glycyl-aspartic acid|Oligopeptides|Binding Sites|Extracellular Matrix|beta2 Integrin|Protein Denaturation|*Tissue Adhesions|Carrier Proteins|Peptide Fragments | |
10688839 Blood 2000 Humans|FGFR1 protein, human|*Receptor, Fibroblast Growth Factor, Type 1|*Myeloproliferative Disorder|CNTRL protein, human|*Cell Cycle Proteins|Translocation, Genetic|*Centrosome|Oncogene Proteins, Fusion|Tyrosine Kinase|Amino Acid Sequence|Phosphorylation|Fibroblast Growth Factors|*Chromosome Structures|*Stem Cell | |
10688912 Proc. Natl. Acad. Sci. U.S.A. 2000 PMC15805 *Insulin|*Leptin|IRS2 protein, human|Insulin Receptor Substrate Proteins|*Signal Transduction|INSR protein, human|Insulin Receptor|Phosphatidylinositol 3-Kinases|Phosphorylation|Proto-Oncogene Proteins c-akt|leptin receptor, human|Receptor, Leptin|Phosphoproteins|*Liver|Proto-Oncogene Proteins|Mitogen-Activated Protein Kinases|Protein-Tyrosine Kinases|*Cell Line | |
10691849 Br. J. Haematol. 2000 Humans|F8 protein, human|*Factor VIII|*Hemophilia A|*Mutation, Missense|Mutation|*Cross Reactions|*Hemostatics|*Cytoplasm|cDNA | |
10692117 J. Invest. Dermatol. 2000 Humans|10-hydroxy-11,12-epoxyeicosa-5,8,14-trienoic acid|*8,11,14-Eicosatrienoic Acid|*Epidermis|*Epidermal Cells|12-Hydroxy-5,8,10,14-eicosatetraenoic Acid|Hydroxyeicosatetraenoic Acids|Arachidonic Acid|12-HPETE|Leukotrienes|Arachidonic Acids|Chromatography, High Performance Liquid|Gas Chromatography Mass Spectrometry|Stereoisomerism|12-Lipoxygenase | |
10692392 J. Biol. Chem. 2000 Humans|Endothelial Cells|*Vascular Endothelial Growth Factors|Vascular Endothelial Cell Growth Factor Receptor|*Adaptor Proteins, Signal Transducing|Receptor Protein-Tyrosine Kinases|*Fibroblast Growth Factors|Receptors, Growth Factor|Signal Transduction|Phospholipase C gamma|Vascular Endothelial Growth Factor A|Vascular Endothelial Growth Factor Receptor-1|SH2 Domain|Phosphorylation|Proto-Oncogene Proteins|Endothelium, Vascular|Isoenzymes | |
10692424 J. Biol. Chem. 2000 *Flavin-Adenine Dinucleotide|alkylglycerone-phosphate synthase|*Alkyl and Aryl Transferases|Amino Acid Sequence|Kinetics|Redox|Catalysis|palmitoyl dihydroxyacetone phosphate|Dihydroxyacetone Phosphate | |
10692433 J. Biol. Chem. 2000 Humans|Mice|Animals|*S Phase|NIH 3T3 Cells|CDK2 protein, human|*Cyclin-Dependent Kinase 2|cdk Proteins|Cell Cycle Proteins|DNA-Binding Proteins|CDC2-CDC28 Kinases|CCNE1 protein, human|Cyclin E|Transcription Factor DP1|E2F Transcription Factors|Retinoblastoma-Binding Protein 1|Cyclins|DNA Replication|Nuclear Proteins|E2F1 Transcription Factor|G1 Phase | |
10693759 Cell 2000 Humans|Animals|SHH protein, human|Sonic Hedgehog Protein|Zinc Finger Protein GLI1|Zinc Finger Protein Gli3|Zinc Finger Protein Gli2|Kruppel-Like Transcription Factors|Embryonic Induction|Body Patterning|Xenopus Proteins|Oncogene Proteins|Signal Transduction|Transcription Factors|Trans-Activators|Repressor Proteins|Gene Expression Regulation, Developmental|Nerve Tissue Proteins|Zinc Finger|*Vertebrate | |
10694380 Biochemistry 2000 Chlorocebus aethiops|Animals|Humans|*UDP Glucose|*Glycoprotein|Amino Acid Sequence|Endoplasmic Reticulum|Folding, Protein|Base Sequence|Transfection|Recombinant Proteins|Peptide, Signal|Catalytic Domain|Glucose|Glucuronosyltransferase|COS-1 Cells|4 alpha-glucanotransferase|*Glycogen Debranching Enzyme System|*Biochemical Phenomena|mRNA | |
10694408 Biochemistry 2000 Cricetinae|Animals|*Sterol Esterase|Lipase|Protein Binding|Phosphorylation|Amino Acid Sequence|Adipose Tissue|CHO Cells | |
10694513 Biochem. Biophys. Res. Commun. 2000 Mice|Animals|CTLA4 protein, human|*CTLA-4 Antigen|PTPN11 protein, human|*Tyrosine Phosphatase, Shp-2|SH2 Domain-Containing Protein Tyrosine Phosphatases|SH2 Domains|Signal Transduction|Protein Tyrosine Phosphatase, Non-Receptor Type 6|Phosphorylation|PI-3 Kinase|Protein-Tyrosine Kinases|T Cells|Abatacept|Lymphocyte Activation|Protein Binding|Antigens, CD|Immunoconjugates|Tyrosine | |
10697413 Prog. Nucleic Acid Res. Mol. Biol. 2000 Humans|Animals|*Alcohol Dehydrogenase|Promoter Regions, Genetic|Transcription Factors|Base Sequence|Regulatory Sequences, Nucleic Acid|Transcription, Genetic|CCAAT-Enhancer-Binding Proteins|Sequence Homology, Nucleic Acid|*Mammals|Cloning, Molecular|Multigene Family|Gene Expression Regulation, Enzymologic|mRNA|Receptors, Retinoic Acid | |
10698200 Endocrinology 2000 gastric inhibitory polypeptide receptor|*Gastric Inhibitory Polypeptide|Iodine-125|*Iodine Radioisotopes|*Receptors, Gastrointestinal Hormone|*Osteoblast|Cyclic AMP|Cell Lines|Insulin Secretion|*B Cells|Messenger RNA|Bone | |
10698523 Oncogene 2000 Animals|Chlorocebus aethiops|CTNNB1 protein, human|*beta Catenin|*Phosphorylation|*Glycogen Synthase Kinase 3 beta|*Axin Protein|*Protein Phosphatase 2|*Adenomatous Polyposis Coli Protein|Trans-Activators|Binding Sites|Wnt Proteins|Repressor Proteins|Calcium-Calmodulin-Dependent Protein Kinases|Protein Binding|Downregulation|Signal Transduction|*Biochemical Phenomena|COS Cells|Adenomatous Polyposis Coli | |
10698680 Biochem. J. 2000 PMC1220886 AKT1 protein, human|*Protein Kinase B|*Phosphatidylinositol 3-Kinases|PIK3CG protein, human|*Class Ib Phosphatidylinositol 3-Kinase|Phosphorylation|Signal Transduction|Proto-Oncogene Proteins|Enzyme Activation | |
10698683 Biochem. J. 2000 PMC1220889 Humans|*Phosphatidylinositol Kinase Type II|phosphatidylinositol 5-phosphate|*Protein Conformation, alpha-Helical|*Phosphate|HeLa Cells|1-phosphatidylinositol-4-phosphate 5-kinase|*Phosphotransferases (Alcohol Group Acceptor)|Phosphatidylinositol Phosphates|*Cell Nucleus|Transfection|Amino Acid Sequence|Green Fluorescent Proteins|Cytosol|Isoenzymes | |
10698692 Biochem. J. 2000 PMC1220898 Humans|Male|Rats|Animals|*AMP-Activated Protein Kinases|*Isoforms|Protein-Serine-Threonine Kinases|Muscle, Skeletal|Multienzyme Complexes|Amino Acid Sequence|mRNA|Subunit, Catalytic|Adenosine Monophosphate | |
10698697 Biochem. J. 2000 PMC1220903 Animals|SLC1A5 protein, human|*Amino Acid Transport System ASC|*Sodium|*Minor Histocompatibility Antigens|*Anions|Glutamine|Amino Acids|Xenopus laevis|Carrier Proteins|Oocytes|Cations|Patch-Clamp Techniques|Membrane Transport Proteins|Biological Transport|Antiport|Membrane Potentials|Alanine|DNA, Complementary | |
10698924 EMBO J. 2000 PMC305622 Humans|3-hydroxy-3-methylglutaryl-coenzyme A|HMGCR protein, human|*HMG CoA Reductase|*Hydroxymethylglutaryl-CoA-Reductases, NADP-dependent|Acyl Coenzyme A|Protein Conformation|Protein Binding|Binding Sites|*Catalysis|Substrate Specificity|Active Site|Hydroxymethylglutaryl-CoA Reductase Inhibitors|Amino Acid Sequence|Models, Molecular|NADP|Cholesterol|Phosphorylation|Sterols | |
10698942 EMBO J. 2000 PMC305640 Animals|*Phosphorylation|Dishevelled Protein|*Embryogenesis|Phosphoproteins|Adaptor Proteins, Signal Transducing|Xenopus laevis|Wnt Proteins|Xenopus Proteins|beta Catenin|Embryo, Nonmammalian|Signal Transduction|Drosophila Proteins|Amino Acid Sequence|Embryo, Mammalian | |
10698974 FASEB J. 2000 Humans|Male|Mice|Animals|*Williams Syndrome|Meiosis|*Chromosome Pairing|cohesins|Chromosomal Proteins, Non-Histone|Cell Cycle Proteins|Synaptonemal Complex|Chromatids|Centromere|Nuclear Proteins|Chromosome Mapping|Phosphoproteins|Amino Acid Sequence|Transcription, Genetic|Sequence Alignment|Sequence Homology, Amino Acid|Gene Deletion|STAG3 protein, human | |
10700176 Nat. Genet. 2000 Humans|*Carcinoma, Hepatocellular|*Liver Neoplasms|CTNNB1 protein, human|beta Catenin|*Mutations|Trans-Activators|Wnt Proteins|Transcription Factors|Axin Protein|Signal Transduction|Genes, APC|Proto-Oncogene Proteins|Adenomatous Polyposis Coli Protein|DNA-Binding Proteins|Repressor Proteins|Transcription, Genetic|Colorectal Cancers|Gene Expression Regulation, Neoplastic | |
10700233 Nat. Med. 2000 Mice|Animals|*Neoplastic Processes|N-Acetylglucosaminyltransferases|Glycans|Signal Transduction|Glycosylation|Golgi Apparatus|Mammary Neoplasms, Animal|Cell Line, Tumor | |
10702308 J. Biol. Chem. 2000 Humans|*Phosphorylation|MAP kinase kinase kinase 7|*MAP Kinase Kinase Kinases|TAB1 protein, human|Adaptor Proteins, Signal Transducing|Signal Transduction|Protein Binding|Interleukin 1|Intracellular Signaling Peptides and Proteins|Binding Protein|HeLa Cells|Mutation | |
10702312 J. Biol. Chem. 2000 Animals|Rats|Humans|4-N-trimethylaminobutyraldehyde dehydrogenase|Escherichia coli|*Aldehyde Oxidoreductases|Escherichia coli Proteins|Base Sequence|Monosaccharide Transport Proteins|Maltose-Binding Proteins|Amino Acid Sequence|cDNA|Cloning, Molecular|gamma-butyrobetaine|Carnitine|ATP-Binding Cassette Transporters|gamma-trimethylaminobutyraldehyde|Aldehydes|Aldehyde Dehydrogenase|Betaine|Kinetics | |
10702794 Oncogene 2000 Humans|MAPK1 protein, human|*Mitogen-Activated Protein Kinase 1|*Protein Tyrosine Phosphatase|MAPK3 protein, human|Mitogen-Activated Protein Kinase 3|*Mitogen-Activated Protein Kinases|PTPN7 protein, human|*Protein Tyrosine Phosphatases, Non-Receptor|Phosphorylation|*MAP Kinase Signaling System|Intracellular Signaling Peptides and Proteins|MAP Kinase, p38|Substrate Specificity|Protein Binding|Kinetics|Amino Acid Sequence|Protein Tyrosine Phosphatase, Non-Receptor Type 6|Transfections | |
10704444 J. Cell Biol. 2000 PMC2174547 *Peroxisomes|*Membrane Proteins|*Intracellular Membranes|*Cytoplasm|Peroxins|*Cytosol|Protein Transport|Amino Acid Sequence|Protein Binding|Cell Line | |
10704531 Glycobiology 2000 Humans|*Saccharomyces cerevisiae|*DNA, Complementary|*Mannosyltransferases|*Yeast, Dried|Amino Acid Sequence|DNA, Fungal|Cloning, Molecular|Nucleotide Sequence|Sequence Homology, Amino Acid|PCR|Mutation | |
10706100 Cancer Res. 2000 *Basigin|MMP1 protein, human|*Matrix Metalloproteinase 1|*Matrix Metalloproteinases|Antigens, Neoplasm|Matrix Metalloproteinase 2|Membrane Glycoproteins|Antigens, CD|Glycoprotein|Immunocytochemistry|*Tumor|*Cell Membrane|Cells, Stromal | |
10706276 Nature 2000 Humans|8-hydroxyguanine|*Guanine|oxoguanine glycosylase 1, human|DNA Glycosylases|DNA-Formamidopyrimidine Glycosylase|*DNA|DNA Repair|DNA Damage|Substrate Specificity|Adenine|Base Pairs|Protein Conformation|*Mutagens|Binding Sites|Models, Molecular|Core, Catalytic|Escherichia coli|Crystallography, X-Ray | |
10706561 Hepatology 2000 Humans|Cricetinae|Animals|Porphyria, Acute Hepatic|*Porphobilinogen Synthase|CHO Cells|Cricetulus|*Porphyrias, Hepatic|Porphyria|Allele|cDNA|Pedigree|DNA|Cloning, Molecular|Mutations|Sequences, Nucleotide | |
10706581 J. Lipid Res. 2000 Humans|Mice|Animals|sterol carrier proteins|*Lipid Metabolism, Inborn Errors|*Peroxisomal Disorders|*Carrier Proteins|Zellweger Syndrome|*Oxidation-Reduction|Peroxisomes|*Liver|Fatty Acids|*Fibroblasts|Bile Acids and Salts|Microbodies|*Lipid Metabolism|Cell Line | |
10706668 J. Immunol. 2000 Humans|Animals|Cattle|vMIP-II|*Chemokines|Chemokines, CC|Chemokine CCL19|Chemokine CCL21|ACKR4 protein, human|Receptors, CCR|Receptors, CCR7|Receptor, CCR10|Chemotaxis, Leukocyte|Ligands|Receptors, Cell Surface|Amino Acid Sequence|Cloning, Molecular|Lymph Nodes|Cell Line|T-Lymphocytes|Dendritic Cells | |
10706702 J. Immunol. 2000 Humans|*Tyrosine|GRB2 protein, human|*GRB2 Adaptor Protein|Receptors, Antigen, B-Cell|*Antigens, CD19|B Cells|Phosphorylation|Signal Transduction|Cell Cycle Proteins|Phospholipase C gamma2|Proto-Oncogene Proteins c-vav|*Cytoplasm|Phosphoproteins|Protein Binding|Intracellular Signaling Peptides and Proteins|Proto-Oncogene Proteins|Phosphatidylinositol 3-Kinases|*Clustering | |
10710310 Science 2000 Mice|Animals|*Tumor Suppressor Protein p53|*B-DNA|CHEK1 protein, human|*Checkpoint Kinase 1|MDM2 protein, human|Proto-Oncogene Proteins c-mdm2|Cell Cycle Proteins|Checkpoint Kinase 2|Phosphorylation|Ataxia Telangiectasia Mutated Proteins|Tumor Suppressor Proteins|DNA Damage|DNA-Binding Proteins|Nuclear Proteins|Protein Kinases|Cell Cycle|Apoptosis|G2 Phase | |
10712517 Mol. Biol. Cell 2000 PMC14828 *Protein-Serine-Threonine Kinases|BMP2 protein, human|Bone Morphogenetic Protein 2|recombinant human bone morphogenetic protein-2|Transforming Growth Factor beta|Bone Morphogenetic Proteins|Receptor, BMP|Bone Morphogenetic Protein Receptors, Type I|Receptors, Transforming Growth Factor beta|BMPR2 protein, human|BMP Type II Receptor|Receptors, Growth Factor|Ligands|*Cell Membrane|Protein Binding|TGFBR2 protein, human|Receptor, Transforming Growth Factor-beta Type II|*Carrier Proteins | |
10712613 Eur. J. Biochem. 2000 Animals|Mice|Humans|Cattle|*cDNA|2-amino-3-ketobutyrate|*Cloning, Molecular|Amino Acids|Keto Acids|Amino Acid Sequence|Base Sequence|Sequence Alignment|Sequence Homology, Amino Acid|*Coenzyme A Ligases|Proteins|Exons|L-threonine 3-dehydrogenase|Alcohol Oxidoreductases|RNA, Messenger|ORFs|Escherichia coli | |
10712905 Curr. Biol. 2000 *Raf-1, Kinase|*Phosphatidylinositol 3-Kinase|PAK3 protein, human|p21-Activated Kinase 3|PAK1 protein, human|Phosphorylation|*Genes, ras|protein kinase N|Protein Kinase C|Phosphatidylinositol 3-Kinases|ras Proteins|Signal Transduction|Proto-Oncogene Proteins|Enzyme Activation|cdc42 GTP-Binding Protein|rac GTP-Binding Proteins|rhoA GTP-Binding Protein|Serine | |
10713148 J. Biol. Chem. 2000 Humans|caspase-activated deoxyribonuclease|*Chromatin|HeLa Cells|*Deoxyribonucleases|DFFB protein, human|*Poly-ADP-Ribose Binding Proteins|*DNA|*Endonucleases|Histone H1|DNA Fragmentation|Caspases|Caspase 3|Apoptosis Regulatory Proteins|Cell Nuclei|Apoptosis|Micrococcal Nuclease|RNA | |
10713150 J. Biol. Chem. 2000 Mice|Animals|*3T3-L1 Cells|*Vesicle-Associated Membrane Protein 2|*Insulin|*Adipocytes|Qc-SNARE Proteins|Qb-SNARE Proteins|*Insulin, Regular, Human|Qa-SNARE Proteins|R-SNARE Proteins|Soluble N-ethylmaleimide-Sensitive-Factor Attachment Protein Receptor|Munc18 Proteins|Protein Transport|Vesicular Transport Proteins|Plasma Membrane|Nerve Tissue Proteins|Muscle Proteins|Protein Binding|Monosaccharide Transport Proteins | |
10713152 J. Biol. Chem. 2000 Humans|Cricetinae|Animals|*Cell Adhesion|*Collagen Type XIII|CHO Cells|Cricetulus|*Collagen|Receptors, Collagen|Integrins|Integrin alpha1beta1|*beta1 Integrin|Integrin alpha1|Protein Binding|Recombinant Proteins|Binding Sites|Collagen Type I|cDNA|Carrier Proteins | |
10713164 Mol. Cell. Biol. 2000 PMC85419 Animals|*Ankyrin Repeat|Drosophila melanogaster|DNA Binding Protein|Immunoglobulin J Recombination Signal Sequence-Binding Protein|Nuclear Proteins|SMRT Co-repressor|Repressor Proteins|Receptors, Notch|Histone Deacetylase|Membrane Proteins|Binding Sites|Amino Acid Sequence|Protein Binding|Signal Transduction|Cell Nucleus|Promoter Regions, Genetic|Mutation | |
10713165 Mol. Cell. Biol. 2000 PMC85422 Humans|Mice|Animals|*Receptors, Steroid|Nuclear Protein|Activation, Transcriptional|Receptors, Nuclear|Gene Expression Regulation|Histone Acetyltransferases|Nuclear Receptor Coactivator 1|Protein Binding|Nuclear Receptor Coactivator 2|Ligands|Amino Acid Sequence|Carrier Proteins | |
10714828 J. Androl. 2000 Male|Humans|Mice|Rats|Animals|glyceraldehyde 3-phosphate dehydrogenase (304-313)|*GAPD|Spermatozoa|Base Sequence|Testis|DNA|Amino Acid Sequence|*Germ Cells|Intron|Exon|Messenger RNA|Mammals|Glycolysis | |
10716435 Nature 2000 Humans|*Ribonucleotide Reductase|*Tumor Suppressor Protein p53|Apoptosis|Cell Line, Tumor|G2 Phase Cell Cycle Checkpoints|*DNA Damage|DNA Repair|Cell Cycle Proteins|ribonucleotide reductase M2|Ribonucleoside Diphosphate Reductase|Cell Division|*Ribonucleotides|Adriamycin|Protein Binding|Messenger RNA | |
10716450 Nature 2000 Pregnancy|Female|Mice|Animals|*Gastrulation|*Trophoblasts|Prospective Studies|Gastrula|Mesoderm|Ectoderm|Endoderm|Germ Layers|Lineages, Cell|T-Box Domain Proteins|Cell Differentiation|Morphogenesis|Embryo, Mammalian|Blastocyst | |
10716625 Int. J. Biochem. Cell Biol. 2000 *Heparan Sulfate Proteoglycans|Syndecans|*Cell Membrane|Heparitin Sulfate|Signal Transduction|Cell Adhesion|Glycosaminoglycans|Cell Differentiation | |
10716985 Proc. Natl. Acad. Sci. U.S.A. 2000 PMC15958 Humans|*Metallothionein|*Zinc|Cadmium|Cysteine|Reagent, Ellman's|Protein Structure, Tertiary|Circular Dichroism|Protein Binding|Amino Acid Sequence|Kinetics|Models, Molecular|Protein Isoforms|Chelating Agents|Hydrogen-Ion Concentration|Proton | |
10717281 Dev. Comp. Immunol. 2000 Animals|Rats|Mice|MBL2 protein, human|*Mannose-Binding Lectin|*Chickens|Collectin|Lectins|Mannose-Binding Protein-Associated Serine Proteases|Complement Activation|Carrier Proteins|Complement C3|Serine Endopeptidases|Amino Acid Sequence|Carbohydrate|MASP-1 protein, rat | |
10719897 Neuron 2000 Mice|Animals|*CLOCK Proteins|*Phylogeny|*Suprachiasmatic Nuclei|Cryptochrome|Period Circadian Proteins|Photoreceptor Cells, Invertebrate|Nuclear Proteins|Eye Proteins|Biological Clocks|Circadian Rhythm|Cell Cycle Proteins|Drosophila Proteins|Gene Expression Regulation|RNA, Messenger|Receptors, G-Protein-Coupled|In Situ Hybridization | |
10720933 Kidney Int. 2000 *Ubiquitination|Ligase, Ubiquitin-Protein|Endosomal Sorting Complexes Required for Transport|Nedd4 Ubiquitin Protein Ligases|*Sodium|Epithelial Sodium Channels|Amino Acid Sequence|Protein Binding|Binding Sites|Calcium-Binding Proteins|Xenopus Proteins|Hypertension|Mutations|Liddle Syndrome|Kidney|UBE2D2 protein, human|Ubiquitin-Conjugating Enzymes|Plasma Membrane | |
10721988 Cell 2000 Animals|telomerase RNA|*Telomerase|Phylogeny|*RNA|Nucleic Acid Conformation|*Vertebrate|Base Sequence|Telomeres|Base Pairing|*Protein Structure, Secondary|Sequence Alignment|Ribonucleoprotein|Ciliophora|Models, Molecular|Cloning, Molecular | |
10721994 Cell 2000 DC-specific ICAM-3 grabbing nonintegrin|*Intercellular Adhesion Molecule-3|Lectin, C-Type|*Cell Adhesion Molecules|ICAM3 protein, human|*Antigens, CD|Receptors, Cell Surface|Dendritic Cells|Antigens, Differentiation|T Cells|Lymphocyte Activation|ICAM1 protein, human|ICAM-1 | |
10722588 Infect. Immun. 2000 PMC97372 Humans|Cricetinae|Mice|Animals|*Escherichia coli|CHO Cells|Cricetulus|*Phagocytosis|Scavenger Receptors, Class A|Macrophages|Receptors, Immunologic|lipoteichoic acid|Lipopolysaccharides|Teichoic Acids|Scavenger Receptors, Class B|Listeriosis|Transfections|Endocytosis | |
10722674 J. Biol. Chem. 2000 Cricetinae|Animals|*Serine C-Palmitoyltransferase|*Serine|CHO Cells|Cricetulus|Acyltransferases|Sphingolipids|Palmitoyl Coenzyme A|Amino Acid Sequence|Saccharomyces cerevisiae|ketodihydrosphingosine|Sphingosine|*Peptides|Proteins|Endoplasmic Reticulum|*Affinity Chromatography|Protein Binding | |
10722704 J. Biol. Chem. 2000 *Phosphoinositide 3 Kinase|*Phosphatidylinositol 3-Kinases|*Chemotaxis|*Receptor, ErbB-4|Signal Transduction|Proto-Oncogene Proteins c-akt|EGFR protein, human|Epidermal Growth Factor Receptor|Phosphorylation|*Isoforms|cimaglermin|Neuregulin-1|Mitogen-Activated Protein Kinases|Proto-Oncogene Proteins|Shc Signaling Adaptor Proteins|Receptor Protein-Tyrosine Kinases|GRB2 Adaptor Protein|Adaptor Proteins, Vesicular Transport | |
10722742 J. Biol. Chem. 2000 TP53 protein, human|*Tumor Suppressor Protein p53|*Ubiquitin|MDM2 protein, human|*Proto-Oncogene Proteins c-mdm2|*RING Finger Domains|UBE2D2 protein, human|Ubiquitin-Conjugating Enzymes|Ligase, Ubiquitin-Protein|Nuclear Proteins|Ubiquitins|Proto-Oncogene Proteins|Proteasome|Ubiquitination|Mutation | |
10723025 Med Res Rev 2000 Humans|*HIV-1|*Reverse Transcription|reverse transcriptase, Human immunodeficiency virus 1|HIV Reverse Transcriptase|Anti-HIV Agents|Reverse Transcriptase Inhibitors|Drug Resistance, Viral|HIV Infections|Protein Conformation|Models, Molecular|Mutation | |
10723029 Bioessays 2000 *RNA Polymerase II|*Promoter Regions, Genetic|Transcription, Genetic|Single Stranded DNA Binding Proteins|Transcription Factors|DNA|Templates, Genetic|Gene Expression Regulation|Escherichia coli | |
10723127 Oncogene 2000 *I-kappa B Kinase|*NF-kappa B|RNA-Dependent Protein Kinase|*RNA, Double-Stranded|I-kappa B Proteins|NFKBIA protein, human|NF-KappaB Inhibitor alpha|Phosphorylation|Signal Transduction|Apoptosis|Poly I-C|Vaccinia virus|Gene Expression Regulation | |
10724160 Nature 2000 WAS protein, human|*Wiskott-Aldrich Syndrome Protein|Wiskott-Aldrich Syndrome|Protein Binding|Actin|Wiskott-Aldrich Syndrome Protein Family|Binding Sites|Amino Acid Sequence|Cytoskeletal Proteins|cdc42 GTP-Binding Protein | |
10724175 Nature 2000 Humans|CHEK2 protein, human|*Checkpoint Kinase 2|*Phosphorylation|BRCA1 protein, human|*BRCA1 Protein|DNA Repair|DNA Damage|Cell Cycle Proteins|Ataxia Telangiectasia Mutated Proteins|Tumor Suppressor Proteins|Serine|DNA-Binding Proteins|Mutations | |
10725331 J. Cell Biol. 2000 PMC2174312 Humans|*Survival of Motor Neuron Complex|Neurodegenerative Diseases|*Gemini of Coiled Bodies|Ribonucleoproteins, Small Nuclear|Spliceosomes|*Cell Nucleolus|Gemin3 Protein|Muscular Atrophy, Spinal|Cell Nucleus|RNA-Binding Proteins|U1 small nuclear RNA|RNA, Small Nuclear|Cytoplasm|DEAD-box RNA Helicases|Nerve Tissue Proteins|Nuclear Proteins|snRNP Core Proteins|Cyclic AMP Response Element-Binding Protein | |
10725339 J. Cell Biol. 2000 PMC2174299 Chlorocebus aethiops|Animals|*beta-Arrestin|*Proteinase Activated Receptor 2|*MAP Kinase Signaling System|MAPK3 protein, human|Extracellular Signal Regulated Kinase 1|MAPK1 protein, human|Mitogen-Activated Protein Kinase 1|*beta-Arrestin 1|*Endocytosis|*Cytoplasm|Arrestins|Signal Transduction|GTP-Binding Proteins|Cytosol|COS Cells|Phosphorylation|Transfection|Kinetics | |
10725395 Proc. Natl. Acad. Sci. U.S.A. 2000 PMC16285 Animals|*Receptor, ErbB-4|*Synapses|Membrane-Associated Guanylate Kinases|*Neurons|Disks Large Homolog 4 Protein|SAP90-PSD95 Associated Proteins|Nerve Tissue Proteins|Intracellular Signaling Peptides and Proteins|Membrane Proteins|*Neuregulins|N Methyl D Aspartate Receptors|PDZ Domains|Hippocampus|Amino Acid Sequence|Yeast Two-Hybrid System|EGFR protein, human|ErbB Receptors|Brain | |
10725696 J. Immunol. 2000 Humans|Mice|Animals|*Chemokine CCL27|CCR10 protein, human|*G Protein Coupled Receptor 2|*Chemokines|Receptors, Chemokine|Chemokines, CC|Amino Acid Sequence|Cell Line|Cloning, Molecular|Transfections|Cells, Cultured|Ccr10 protein, mouse | |
10725697 J. Immunol. 2000 CCL27 protein, human|*Chemokine CCL27|Endothelial Cells|CCR10 protein, human|*G Protein Coupled Receptor 2|*Receptors, Chemokine|*Skin|Chemokines|Chemokines, CC|Keratinocytes|T Cells|Signal Transduction | |
10727444 J. Clin. Invest. 2000 PMC377455 Humans|X-linked sideroblastic anemia|*Anemia, Sideroblastic|*Succinate-CoA Ligases|*Haem|5-Aminolevulinate Synthetase|*Ferrochelatase|Genetic Diseases, X-Linked|Pyridoxin|*Aminolevulinic Acid|Amino Acid Sequence|succinyl-coenzyme A|Acyl Coenzyme A|X Chromosome|cDNA Library|Bone Marrow | |
10727522 Mol. Pharmacol. 2000 Male|Animals|Rats|Humans|*Receptors, Lysophosphatidic Acid|*Prostate|HEK293 Cells|*Cloning, Molecular|lysophosphatidic acid|Lysophospholipids|Receptors, Cell Surface|Amino Acid Sequence|Base Sequence|Ligands|mRNA|Sequence Homology, Amino Acid|DNA | |
10727532 Mol. Pharmacol. 2000 *G-Protein-Coupled Receptor Kinase 2|*Signal Transduction|Phosphorylation|RGS4 protein|RGS Proteins|Cyclic AMP-Dependent Protein Kinases|GTP-Binding Protein alpha Subunits, Gq-G11|beta-Adrenergic Receptor Kinases|Receptors, G-Protein-Coupled|Protein Binding|Binding Sites|Transfections|Cell Line|Inositol Phosphates|Thyrotropin Receptor | |
10727776 Prog. Neurobiol. 2000 Mice|Animals|*Myelin Sheath|Schwann Cells|Axons|Myelin Basic Protein|Sciatic Nerve|Cell Differentiation|Mice, Transgenic|Organogenesis | |
10727845 Biochim. Biophys. Acta 2000 Humans|*Ascorbic Acid|2,3-Diketogulonic Acid|Dehydroascorbic Acid|Oxidation-Reduction|Lens, Crystalline|Cataract|Hydrogen Peroxide|Chromatography, High Performance Liquid|Magnetic Resonance Spectroscopy|Oxalates | |
10728666 Cancer Res. 2000 Humans|Bloom syndrome protein|TOP3A protein, human|*DNA Topoisomerases, Type I|*RecQ Helicases|Bloom Syndrome|DNA, Cruciform|Nuclear Proteins|Recombination, Genetic|Transcription Factors|*Germ Cells|*Diploidy|Escherichia coli|Promyelocytic Leukemia Protein | |
10729221 Genomics 2000 Humans|Amino Acid Sequence|cDNA|Shal Potassium Channels|Cloning, Molecular|Exon|Cytoplasm|Cell Line|Sequence Homology, Amino Acid|RNA, Messenger|Brain|Tissue Distribution | |
10731522 Chem. Biol. Interact. 2000 Humans|*Microsomes, Liver|*Cytochrome P-450 CYP2E1|*Carbon Tetrachloride|Cytochrome P-450 Enzyme System|Cytochrome P-450 Enzyme Inhibitors|Cytochrome P-450 CYP2B6|Cytochrome P-450 CYP3A|alpha-naphthoflavone|Benzoflavones | |
10733484 Blood 2000 Male|Female|Humans|Aged|Child|*Glutamate-Cysteine Ligase|*Mutation, Missense|*Haemolytic Anaemia|Homozygote|Glutathione|Base Sequence|Erythrocytes|Codon|Mutation|Amino Acid Metabolism, Inborn Errors|gamma-glutamylcysteine|Dipeptides | |
10733526 Genes Dev. 2000 PMC316466 *Anaphase Promoting Complex|Cell Cycle Proteins|Cdc20 Proteins|Ligase, Ubiquitin-Protein|Cdh1 Proteins|CDH1 protein, human|*Cadherins|Saccharomyces cerevisiae Proteins|Mitosis|*Antigens, CD|Cyclin B|Ubiquitin|Amino Acid Sequence|Cell Cycle | |
10733528 Genes Dev. 2000 PMC316463 Mice|Animals|Suprachiasmatic Nucleus|CLOCK Proteins|ARNTL Transcription Factors|DNA-Binding Proteins|Trans-Activators|Period Circadian Proteins|Gene Expression Regulation|Motifs, E-Box|Promoter Regions, Genetic|Circadian Rhythm|Nuclear Proteins|Cell Cycle Proteins|RNA, Messenger|Gene Expression|Leucine Zipper|*Pacemaker, Artificial | |
10733530 Genes Dev. 2000 PMC316461 Humans|Mice|Animals|TP53 protein, human|*Tumor Suppressor Protein p53|*Apoptosis|DNA-Binding Proteins|Transcription Factor DP1|Cell Cycle Proteins|E2F Transcription Factors|E2F1 Transcription Factor|Nuclear Proteins|Retinoblastoma-Binding Protein 1|Transcriptional Activation|Promoter Regions, Genetic|Gene Expression Regulation|Membrane Protein|Genes, Tumor Suppressor|PERP protein, human | |
10733567 Mol. Cell. Biol. 2000 PMC85480 Animals|Ribonucleoproteins, Small Nucleolar|*Cell Nucleolus|*Ribonucleoproteins|Saccharomyces cerevisiae Proteins|Small Nucleolar RNA|Saccharomyces cerevisiae|Ribonucleoproteins, Small Nuclear|RNA Precursors|small protein B|RNA-Binding Proteins|fibrillarin|Chromosomal Proteins, Non-Histone|Nuclear Proteins|18S RRNA | |
10733573 Mol. Cell. Biol. 2000 PMC85486 Animals|*Protein Kinase|*Glucose|Saccharomyces cerevisiae|Saccharomyces cerevisiae Proteins|Eukaryotic Initiation Factor-2|Phosphorylation|Transcription Factors|DNA-Binding Proteins|Protein-Serine-Threonine Kinases|tRNA|Histidyl-tRNA Synthetase|Peptide Elongation Factors|Protein Biosynthesis|Transcription, Genetic|Vacuoles|Amino Acids|Sequence Homology, Amino Acid|RNA, Messenger | |
10734051 J. Biol. Chem. 2000 Mice|Animals|oxidized low density lipoprotein|*Phospholipids|*Lipoproteins, LDL|*CD36 Antigens|*Lipoprotein|Receptors, Oxidized LDL|Apo B|APOB protein, human|Apolipoprotein B-100|*Oxidation-Reduction|Receptors, Immunologic|Scavenger Receptors, Class B|Macrophages|Macrophages, Peritoneal|Ligands|Phosphatidyl Choline | |
10734111 J. Biol. Chem. 2000 Humans|Cricetinae|Animals|*Epidermal Growth Factor|*Glycosylation|CHO Cells|Cricetulus|Fucose|Receptor, Notch1|Membrane Protein|Receptors, Cell Surface|Amino Acid Sequence|Ligands|*Mammals|Linkages, Carbohydrate|Glucose|NOTCH1 protein, human | |
10734115 J. Biol. Chem. 2000 Humans|*Bloom Syndrome|*DNA Topoisomerases, Type I|Saccharomyces cerevisiae|Bloom syndrome protein|*RecQ Helicases|*Isomerases|Recombination, Genetic|Protein Binding|Phenotype|SGS1 protein, S cerevisiae|Saccharomyces cerevisiae Proteins | |
10734128 J. Biol. Chem. 2000 Female|Mice|Animals|*LH beta|Immediate-Early Proteins|Binding Sites|Homeodomain Proteins|Repressor Proteins|Fushi Tarazu Transcription Factors|Gene Expression Regulation|Promoter Regions, Genetic|Zinc Fingers|Luteinizing Hormone|Early Growth Response Protein 1|Krox20 Protein|Neoplasm Proteins|Steroidogenic Factor 1|Gonadotropin-Releasing Hormone | |
10734143 J. Biol. Chem. 2000 *Transcription Factor IIH|*Xeroderma Pigmentosum|*DNA Damage|Nucleotide Excision Repair|Xeroderma Pigmentosum Group D Protein|Transcription Factors|DNA|*Cell Nucleus | |
10734310 Oncogene 2000 HGF protein, human|*Hepatocyte Growth Factor|*Phospholipase C gamma|Endothelial Cells|GRB2 protein, human|*GRB2 Adaptor Protein|MET protein, human|Hepatocyte Growth Factor Receptor|Phosphorylation|Signal Transduction|Epidermal Growth Factor|Phosphoproteins|src Homology Domains|Tyrosine|PI3-Kinase|Mitogen-Activated Protein Kinases|Protein Kinase C | |
10741385 Res. Commun. Mol. Pathol. Pharmacol. 2000 Humans|*Neutrophils|*Calcium Ionophores|*Captopril|*Leukotrienes|Leukotriene B4|A23187|Arachidonic Acid|SRS-A|Arachidonic Acids | |
10741631 Clin. Pharmacol. Ther. 2000 Humans|*Acetaminophen|*Cytochrome P-450 CYP2E1|*Cytochrome P-450 CYP3A|Analgesics, Non-Narcotic|quinone|Benzoquinones|Microsomes, Liver|N-acetyl-4-benzoquinoneimine|Imines|Liver|CYP1A2 protein, human|CYP1A2 | |
10742600 Biochim. Biophys. Acta 2000 Animals|Humans|Mice|neolactotetraosylceramide alpha-2,3-sialyltransferase|N-acetyllactosaminide alpha-2,3-sialyltransferase|galactosyl-1-3-N-acetylgalactosaminyl-specific 2,6-sialyltransferase|*Sialyltransferases|*Cloning, Molecular|Amino Acid Sequence|cDNA|Base Sequence|PCR|DNA Primers|Substrate Specificity|Carbohydrate Sequence|*Cell Lines|Sequence Homology, Amino Acid|Chicken|mRNA | |
10744696 J. Biol. Chem. 2000 Mice|Animals|RHOA protein, human|*rhoA GTP-Binding Protein|cdc42 GTP-Binding Protein|Proto-Oncogene Proteins c-vav|rac1 GTP-Binding Protein|Oncogene Proteins|Cell Cycle Proteins|Signal Transduction|Lamellipodia|Protein Structure, Tertiary|3T3 Cells|NIH 3T3 Cells|Transfection | |
10744726 J. Biol. Chem. 2000 *Tumor Necrosis Factor-alpha Converting Enzyme|*Tumor Necrosis Factor-alpha|ADAM Proteins|Cell Membrane|*Receptor, ErbB-4|ErbB Receptors|Amino Acid Sequence|Cell Line|Tetradecanoylphorbol Acetate|Isoforms|Transfection|Carrier Proteins | |
10744741 J. Biol. Chem. 2000 Humans|FEN1 protein, human|*Flap Endonucleases|*Proliferating Cell Nuclear Antigen|Endodeoxyribonucleases|Base Sequence|DNA Repair|Substrate Specificity|DNA Primers | |
10744763 J. Biol. Chem. 2000 Humans|Animals|Swine|*Focal Adhesion Protein-Tyrosine Kinases|geldanamycin|*Mitogen-Activated Protein Kinase 11|*Vascular Endothelial Growth Factor A|*Actins|*Phosphorylation|*Vascular Endothelial Growth Factor B|Endothelial Cells|PTK2 protein, human|*Focal Adhesion Kinase 1|KDR protein, human|*VEGFR-2|*Lactams, Macrocyclic|*Benzoquinones|*Cell Migration|Paxillin|Signal Transduction|FLT1 protein, human | |
10744977 Curr. Biol. 2000 Humans|RAD52 protein, human|*Rad52 DNA Repair and Recombination Protein|Saccharomyces cerevisiae|Rad51 Recombinase|DNA, Single-Stranded|Saccharomyces cerevisiae Proteins|DNA Repair|DNA-Binding Proteins|Recombination, Genetic|DNA Helicases|DNA|Protein Binding|Ionizing Radiation|Escherichia coli|RAD52 protein, S cerevisiae | |
10745006 Structure 2000 Humans|*Maple Syrup Urine Disease|*Dehydrogenase, Alpha-Keto Acid|Ketone Oxidoreductases|Multienzyme Complexes|Mutations|*Databases, Genetic | |
10745013 Structure 2000 Humans|G6PD protein, human|*Glucosephosphate Dehydrogenase|*NADP|Glucose-6-Phosphate Dehydrogenase Deficiency|Protein Conformation|Binding Sites|Models, Molecular|Point Mutations|*Metabolic Diseases|Favism|Genes, X-Linked | |
10746781 Tissue Antigens 2000 Humans|*Chromosome 17|*Immunoreceptor Tyrosine-Based Inhibition Motif|Amino Acid Sequence|Immunoglobulin|Base Sequence|Intron|Membrane Glycoproteins|Sequence Homology, Amino Acid|Genome|Exons|Multigene Family|Epitopes|*Protein Domains|*Chromosome Structures | |
10747026 EMBO J. 2000 PMC310227 Tifab protein, human|*TNF Receptor-Associated Factor 6|*Interleukin 1|*Signal Transduction|NF-kappa B|protein kinase C zeta|Protein Kinase C|Interleukin-1 Receptor-Associated Kinases|IKK beta|TRAF2|Adaptor Proteins, Signal Transducing|Myeloid Differentiation Factor 88|*Gene Expression Regulation|Receptors, Interleukin-1|Protein Binding|RELA protein, human|Transcription Factor RelA|Tumor Necrosis Factor-alpha | |
10747039 EMBO J. 2000 PMC310240 Humans|*Alkylators|*Zinc|*Alkylations|O(6)-Methylguanine-DNA Methyltransferase|DNA Repair|Motif, HTH|Protein Conformation|DNA Damage|Guanine|Protein Binding|Binding Sites|Amino Acid Sequence|Models, Molecular|Nucleotides|Active Site|Mutagenesis, Site-Directed|Cysteine | |
10747087 J. Cell Biol. 2000 PMC2175085 *SNARE Proteins|Golgi Apparatus|Saccharomyces cerevisiae|Saccharomyces cerevisiae Proteins|Vesicular Transport Proteins|Membrane Fusion|Endoplasmic Reticulum|rab GTP-Binding Proteins|Qb-SNARE Proteins|R-SNARE Proteins|GTP-Binding Proteins|Biological Transport|Protein Binding|*Membranes|YPT1 protein, S cerevisiae | |
10747093 J. Cell Biol. 2000 PMC2175094 Growth Cones|Axons|Synaptic Vesicle|*Biological Transport|Neurons|Neural Cell Adhesion Molecules|Kinesin|Organelles|Membrane Glycoproteins|Neurotrophins|Cell Adhesion Molecules|Cells, Cultured | |
10747096 J. Cell Biol. 2000 PMC2175102 vasodilator-stimulated phosphoprotein|*Arp2-3 Complex|*Phosphoproteins|SLP-76 signal Transducing adaptor proteins|*Adaptor Proteins, Signal Transducing|*Microfilament Proteins|*Cell Adhesion Molecules|*Actin Cytoskeleton|WAS protein, human|Wiskott-Aldrich Syndrome Protein|*Signal Transduction|T Cell Receptor|Actin|Carrier Proteins|ENA-VASP proteins|*DNA-Binding Proteins|Cytoskeleton|Lymphocyte Activation | |
10747208 Physiol. Rev. 2000 *Muscle, Skeletal|Tropomyosin|Myosin|Actins|Muscle Contraction|Troponin C|*Muscle, Striated|Sarcomeres|Actin Filament|Troponin I|Protein Binding|Calcium|Movement|Models, Biological|Kinetics | |
10747884 J. Biol. Chem. 2000 Chlorocebus aethiops|Animals|Humans|*Glucocorticoid|*Receptors, Glucocorticoid|*Mutagenesis, Site-Directed|Protein Binding|*Steroids|Ligands|*Receptors, Steroid|Binding Sites|Protein Structure, Tertiary|Mutation|Transfection|Amino Acids|Models, Molecular|COS Cells|Hydrogen Bond | |
10748018 J. Biol. Chem. 2000 *Myosin-Light-Chain Kinase|*Phosphorylation|*p21-Activated Kinases|Myosin Regulatory Light Chains|Calmodulin|Myosin II|Muscle Contraction|Actins|Muscle, Smooth|Post-Translational Modifications|Protein Binding | |
10748026 J. Biol. Chem. 2000 CTNNB1 protein, human|*beta Catenin|CASP3 protein, human|*Caspase 3|*Transcriptional Activation|CDH1 protein, human|E Cadherin|CTNNA1 protein, human|alpha Catenin|Caspases|gamma Catenin|Apoptosis|Trans-Activators|*Proteolysis|Cell Adhesion|Cell Line|*Cell Death|Antigens, CD | |
10748047 J. Biol. Chem. 2000 Humans|Male|Female|Mice|Animals|24-hydroxycholesterol|CYP7B1 protein, human|*Cytochrome P450 Family 7|steroid hormone 7-alpha-hydroxylase|*Steroid Hydroxylases|27-hydroxycholesterol|*Hydroxycholesterols|Cytochrome P-450 Enzyme System|Bile Acids|Liver|Hydroxylations|*Cloning, Molecular|cDNA|Substrate Specificities|mRNA|Aryl Hydrocarbon Hydroxylases | |
10748049 J. Biol. Chem. 2000 Humans|Rats|Male|Mice|Animals|Phylogeny|Amino Acid Sequence|*Lysosomes|cDNA|ATP-Binding Cassette Transporters|Biological Transport|mRNA|Sequence Homology, Amino Acid|Cloning, Molecular|RNA Splicing|Adenosine Triphosphate | |
10748112 J. Biol. Chem. 2000 Humans|HEK293 Cells|histone deacetylase 3|*Histone Deacetylase|HDAC8 protein, human|Repressor Proteins|HDAC1 protein, human|Histone Deacetylase 1|Histone Deacetylase Inhibitors|trichostatin A|Hydroxamic Acids|Amino Acid Sequence|Acetylation|Cloning, Molecular|Sequence Alignment|Transcription, Genetic|Acetyltransferases, Histone|Histone | |
10748235 J. Exp. Med. 2000 PMC2193169 Mice|Animals|invariant chain|*Cathepsin F|*Antigens, Differentiation, B-Lymphocyte|*Class II Major Histocompatibility Molecules|cathepsin S|Cathepsins|Cathepsin L|Antigen Presenting Cells|Antigen Presentation|Protease Inhibitors, Cysteine|*Macrophages|CTSZ protein, human|Cathepsin Z|*Peptides | |
10749138 Cancer Res. 2000 Humans|CTNNB1 protein, human|*beta Catenin|APC protein, human|Adenomatous Polyposis Coli Protein|*Adenomatous Polyposis Coli|Transcription Factors|Trans-Activators|Transcription Factor 7-Like 2 Protein|Colorectal Cancers|DNA-Binding Proteins|Transcription, Genetic|Gene Expression Regulation, Neoplastic|Colon Cancer|Signal Transduction | |
10749680 Biochem. J. 2000 PMC1220983 Humans|Mice|Swine|Animals|Endothelial Cells|KDR protein, human|*Kinase Insert Domain Receptor|FLT1 protein, human|Vascular Endothelial Growth Factor Receptor-1|Receptors, Vascular Endothelial Growth Factor|*Protein Binding|Vascular Endothelial Growth Factors|Receptor Protein-Tyrosine Kinases|Phosphorylation|Receptors, Growth Factor|Signal Transduction|src Homology Domains|Vascular Endothelial Growth Factor A|*Transfections|*Collagen|Shc Signaling Adaptor Proteins | |
10749848 J. Biol. Chem. 2000 Animals|Chlorocebus aethiops|Humans|long-chain-fatty-acid-CoA ligase|*Cholate|choloyl-CoA synthetase|*Coenzyme A Ligases|Saccharomyces cerevisiae Proteins|*Liver|Amino Acid Sequence|COS-1 Cells|Sequence Homology, Amino Acid|Cloning, Molecular|Fatty Acids|Bile Acids|Substrate Specificity|Cholic Acid|Repressor Proteins|Transfection | |
10749855 J. Biol. Chem. 2000 Humans|N-acylneuraminate-9-phosphate synthase|*N-Acetylneuraminic Acid|*Phosphate|Escherichia coli|Oxo-Acid-Lyases|N-acetylneuraminate synthase|Sialic Acids|Sugar Acids|N-acetylmannosamine 6-phosphate|Hexosamines|Amino Acid Sequence|Substrate Specificity|*Nitric Oxide Synthase|Sugar Phosphates|Cloning, Molecular | |
10749889 J. Biol. Chem. 2000 Humans|*Receptor, IGF Type 1|*Estrogen Receptor alpha|HEK293 Cells|IGF1R protein, human|*Receptors, Somatomedin|IGF1 protein, human|Insulin-Like Growth Factor I|MAPK3 protein, human|Extracellular Signal Regulated Kinase 1|Signal Transduction|Phosphorylation|Estradiol|Mitogen-Activated Protein Kinases|Phosphatidylinositol 3-Kinases|Receptors, Estrogen|Cellular Proliferation|MAP Kinase Signaling System|Tumor Cells, Cultured | |
10751187 Development 2000 Animals|*Drosophila|*Calmodulin|*Axons|Drosophila Proteins|Growth Cones|*Signal Transduction|Receptors, Immunologic|Nerve Tissue Proteins|Central Nervous System|Gene Expression Regulation, Developmental|*Neurogenesis|Nuclear Family | |
10751307 J. Biol. Chem. 2000 Humans|Animals|*DNA Polymerase III|DNA Replication|Proliferating Cell Nuclear Antigen|Amino Acid Sequence|*Mammals|Protein Subunits|Schizosaccharomyces pombe|Chromatography, Affinity|Western Blotting | |
10751414 J. Biol. Chem. 2000 Mice|Humans|Animals|sphingosine kinase|HEK293 Cells|*Phosphotransferases (Alcohol Group Acceptor)|sphingosine kinase 2, human|sphingosine 1-phosphate|Lysophospholipids|*Cloning, Molecular|safingol|Sphingosine|erythro-dihydrosphingosine|erythro-(2R,3S)-sphingosine|*Protein Isoforms|*Mammals|Amino Acid Sequence|Blotting, Northern|DNA, Complementary|Phosphorylation|Transfection | |
10753843 Blood 2001 Humans|sphingosine 1-phosphate|HEK293 Cells|lysophosphatidic acid|*Lysophospholipids|dihydrosphingosine 1-phosphate|*Sphingosine|sphingosine phosphorylcholine|Receptors, Lysophospholipid|*Ligands|Receptors, G-Protein-Coupled|Receptors, Cell Surface|Signal Transduction|Phosphorylcholine|Mitogen-Activated Protein Kinases|Calcium|Transfections|Pertussis Toxin | |
10753868 J. Biol. Chem. 2001 Humans|Animals|*Uridine Diphosphoglucose|GPRC5C protein, human|*Receptors, G-Protein-Coupled|P2RY14 protein, human|Receptors, Purinergic P2Y|Receptors, Purinergic P2|Signal Transduction|Glucose | |
10753869 J. Biol. Chem. 2001 Humans|HGF protein, human|*Hepatocyte Growth Factor|HEK293 Cells|*GTPase|GAB1 protein, human|CRKL protein|*Nuclear Proteins|CRK protein, human|Proto-Oncogene Proteins c-crk|*Transductions, Signal|RAPGEF1 protein, human|C3G Protein|MET protein, human|Receptor, HGF|SH2 Domain|GRB2 protein, human|GRB2 Adaptor Protein|Phosphoproteins | |
10753883 J. Biol. Chem. 2001 Animals|Chlorocebus aethiops|*Inositol Polyphosphate 5-Phosphatases|myo-inositol-1 (or 4)-monophosphatase|Phosphoric Monoester Hydrolases|Amino Acid Sequence|Base Sequence|Phosphatidylinositol|Phosphatidylinositol Phosphates|cDNA|Cloning, Molecular|COS-7 Cells|Substrate Specificity|Cell Membrane|Cytosol|Recombinant Proteins|Inositol Phosphates|Hydrolysis | |
10753906 J. Biol. Chem. 2001 Humans|Animals|Cattle|*Vitamin A|trans-retinol dehydrogenase|retinol dehydrogenase|*Alcohol Oxidoreductases|11-cis-Retinal|*Retina|Rod Outer Segment|Photoreceptor Cells|Blotting, Western|NADPH|Blotting, Northern|In Situ Hybridization|Amino Acid Sequence | |
10753910 J. Biol. Chem. 2001 PDPK1 protein, human|*3-Phosphoinositide-Dependent Protein Kinases|Phosphatidylinositol 3-Kinases|*Signal Transduction|Phosphorylation|protein kinase C kinase|Protein Kinase C|Cell Line|Amino Acid Sequence|rho GTPases|rhoB GTP-Binding Protein | |
10753916 J. Biol. Chem. 2001 Animals|Humans|Cricetinae|*N-Acetylglucosaminyltransferases|CHO Cells|Cricetulus|*Cloning, Molecular|UN1 sialoglycoprotein, human|Leukosialin|Amino Acid Sequence|Glycans|Base Sequence|DNA, Complementary|Magnetic Resonance Spectroscopy|Mucin|*Thymus Plant|RNA, Messenger|*Carbohydrate Metabolism|Sequence Homology, Amino Acid | |
10754332 J. Immunol. 2001 Mice|Animals|*src-Family Kinases|*Neutrophils|N-Formylmethionine Leucyl-Phenylalanine|Neutrophil Activation|Phosphorylation|p38 Mitogen-Activated Protein Kinases|Protein-Tyrosine Kinases|Signal Transduction|Cell Degranulation|*Chemotactic Factors|*Mitogen-Activated Protein Kinase 14 | |
10757782 Mol. Cell. Biol. 2000 PMC85557 Humans|SPT5 transcriptional elongation factor|*Transcriptional Elongation Factors|CDK9 protein, human|Cyclin-Dependent Kinase 9|P-TEFb|RNA Polymerase II|*Chromosomal Proteins, Non-Histone|Cyclin T1|Phosphorylation|Transcription, Genetic|HIV Long Terminal Repeat|tat Gene Products, Human Immunodeficiency Virus|Dichlororibofuranosylbenzimidazole|Cyclin-Dependent Kinases|Transcription Factors|*Gene Expression Regulation|Protein-Serine-Threonine Kinases|Cyclins | |
10757784 Mol. Cell. Biol. 2000 PMC85565 Humans|Animals|XRCC4 protein, human|*DNA-Binding Proteins|DNA Ligase ATP|*DNA|DNA Ligases|DNA-Activated Protein Kinase|Antigens, Nuclear|DNA Repair|Ku Autoantigen|DNA Helicases|Nuclear Proteins|DNA Damage|Protein Binding|Phosphorylation|*Electron Transport Complex IV|HeLa Cells | |
10757792 Mol. Cell. Biol. 2000 PMC85596 Animals|Chlorocebus aethiops|*Phosphatidylethanolamine Binding Protein|*Extracellular Signal Regulated Kinases|Signal Transduction|Proto-Oncogene Proteins c-raf|Phosphorylation|MAPK3 protein, human|Extracellular Signal Regulated Kinase 1|MAP2K1 protein, human|MAP Kinase Kinase 1|Carrier Proteins|Androgen-Binding Protein|Phospholipid Transfer Proteins|COS Cells|Binding Sites | |
10757793 Mol. Cell. Biol. 2000 PMC85601 *Replication Origin|*Cyclin-Dependent Kinases|*S Phase|*Replication Protein A|Saccharomyces cerevisiae|Saccharomyces cerevisiae Proteins|DNA Replication|Cell Cycle Proteins|Origin Recognition Complex|Protein-Serine-Threonine Kinases|Nuclear Proteins|Chromosomal Proteins, Non-Histone|Phosphorylation|Chromatin|Protein Kinases|Cell Cycle|Carrier Proteins | |
10757800 Mol. Cell. Biol. 2000 PMC85610 *Transforming Growth Factor beta|SMAD7 protein, human|*Smad7 Protein|SMAD2 protein, human|Smad2 Protein|*Signal Transduction|SMAD3 protein, human|Smad3 Protein|SMAD6 protein, human|Smad6 Protein|Transforming Growth Factor beta Receptor|Protein-Serine-Threonine Kinases|Smad Proteins|Trans-Activators|Activin Receptors, Type I|Phosphorylation|Transcription, Genetic|Receptor, Transforming Growth Factor-beta Type I | |
10757804 Mol. Cell. Biol. 2000 PMC85614 Mice|Animals|*SOXE Transcription Factors|High Mobility Group Proteins|Transcription Factors|DNA-Binding Proteins|*Glia|Binding Sites|Gene Expression Regulation|Promoter Regions, Genetic|Myelin P0 Protein|TYRP1 protein, human|*Membrane Glycoproteins|*Gene Expression|Schwann Cells|Myelin Sheath|Transfections|Mutation|Sox10 protein, mouse | |
10759149 Pediatr. Res. 2000 Pregnancy|Female|Mice|Animals|*Lactation|*Golgi Apparatus|Mammary Glands, Animal|Glucose Transporter|Monosaccharide Transport Proteins|Cells, Epithelial|Lactose|Glucose|Plasma Membrane|Coatomer Protein|Weaning|Human Milk|Cytoplasm|Immunofluorescence|Biological Transport | |
10759542 Proc. Natl. Acad. Sci. U.S.A. 2000 PMC18122 Humans|nuclear factor Y|*CCAAT-Binding Factor|*Binding Sites|*Promoter Regions, Genetic|CCAAT-Enhancer-Binding Proteins|SREBP 1a|Transcription, Genetic|Nuclear Proteins|Genes, Reporter|*Sterols|Luciferase|Sp1 Transcription Factor|FASN protein, human|*Fatty Acid Synthase, Type I|Protein Binding|Electrophoretic Mobility Shift Assay|Transfection|Mutation | |
10759568 Proc. Natl. Acad. Sci. U.S.A. 2000 PMC18143 Humans|Animals|TOP1 protein, human|*DNA Topoisomerases, Type I|SUMO-1 Protein|*SUMO-Conjugation|Saccharomyces cerevisiae|*DNA Damage|UBB protein, human|Ubiquitin|Saccharomyces cerevisiae Proteins|Small Ubiquitin-Related Modifier Proteins|Ubiquitin-Conjugating Enzymes|Ubiquitins|Protein Binding|*Isomerases|DNA|Mutation | |
10759852 Eur. J. Biochem. 2000 Humans|*Blood Platelets|*Receptors, Purinergic P2Y1|*ADP Kinase|Thromboxane A2|U46619|Platelet Aggregation|Adenosine Diphosphate|Platelet Activation|Platelet Glycoprotein GPIIb-IIIa Complex|Purinergic P2 Receptor Antagonists|Adenosine 2'-Phosphate|Thromboxanes|Receptor, Prostaglandin H2|2-propylthio-D-beta,gamma-difluoromethylene ATP|Adenosine Triphosphate|Signal Transduction|Enzyme Inhibitors|Aspirin | |
10760272 Proc. Natl. Acad. Sci. U.S.A. 2000 PMC18131 Animals|Rats|glycerophosphodiester phosphodiesterase|*Phosphoric Diester Hydrolases|Amino Acid Sequence|Integral Membrane Protein|Plasma Membrane|RGS Proteins|Sequence Homology, Amino Acid|G Protein|Signal Transduction|Cell Line|*Membrane | |
10760286 Proc. Natl. Acad. Sci. U.S.A. 2000 PMC18191 Animals|Humans|*Saccharomyces cerevisiae|*Ultraviolet Rays|*Mutagenesis|Saccharomyces cerevisiae Proteins|DNA polymerase zeta|DNA-Directed DNA Polymerase|Mutations|DNA Damage|Mutagens|RNA, Anti-Sense|cDNA|REV1 protein, human|Nuclear Proteins|Nucleotidyltransferases|REV1 protein, S cerevisiae | |
10761932 Cell 2000 *COP-Coated Vesicles|*GTPase|ADP-Ribosylation Factor 1|Coat Protein Complex I|Coatomer Protein|*Protein Transport|Guanosine Triphosphate|Golgi Apparatus|Biological Transport|Coated Vesicles|Hydrolysis|Amino Acid Sequence|Membrane Proteins|Binding Site|Cytoplasm|Kinetics | |
10764623 Semin. Immunol. 2000 *NK Cells|SH2D1A protein, human|Signaling Lymphocytic Activation Molecule Associated Protein|SLAMF1 protein, human|Signaling Lymphocytic Activation Molecule Family Member 1|*Immunoglobulin|Signaling Lymphocytic Activation Molecule Family|CD2 Antigens|Receptors, Immunologic|Antigens, CD|Lymphocyte Activation|Receptors, Cell Surface|T Cells|*Protein Binding|Membrane Glycoproteins|X Linked Lymphoproliferative Syndrome|CD58 Antigens|Interferon-gamma | |
10764645 Science 2000 *Molecular Chaperones|Calnexin|calreticulin, human|Calreticulin|*Endoplasmic Reticulum|*Glycoprotein|molecular chaperone GRP78|Heat-Shock Proteins|Protein Folding|Calcium-Binding Proteins|Ribonucleoproteins|Viral Envelope Proteins|Glycosylation|Protein Binding|Glycans | |
10764727 J. Biol. Chem. 2000 Rats|Humans|Mice|Animals|NGFR protein, human|*Receptors, Nerve Growth Factor|*Signal Transduction|Receptor, Nerve Growth Factor|*Nerve Tissue Proteins|*Cell Death|Neurotrophins|PC12 Cells|Apoptosis|Apoptosis Regulatory Proteins|Nerve Cells|Oligodendrocytes|Yeast Two-Hybrid System | |
10764807 J. Biol. Chem. 2000 Humans|Cattle|Animals|Mice|*Serine-tRNA Ligase|*tRNA|Amino Acid Sequence|Base Sequence|*Mammals|Nucleic Acid Conformation|Mitochondria|Codons|Substrate Specificity|cDNA|Kinetics|Sequence Homology, Amino Acid | |
10764818 J. Biol. Chem. 2000 Humans|Animals|Mice|phosphoinositide 5-phosphatase|*DNA, Complementary|*Phosphatases|Amino Acid Sequence|Phosphatidylinositol|Phosphatidylinositol Phosphates|Inositol Phosphates|Base Sequence|Northern Blotting|Cloning, Molecular|Sequence Homology, Amino Acid|Substrate Specificity|mRNA|Hydrolysis|Inositol-Polyphosphate 5-Phosphatase|Tissue Distribution|Cell Lines | |
10766245 Nature 2000 *Phosphorylation|Ataxia-Telangiectasia|Cell Cycle Proteins|Ataxia Telangiectasia Mutated Proteins|Tumor Suppressor Proteins|DNA-Binding Proteins|Nuclear Proteins|*S Phase Checkpoint|Sensitivity, Radiation|Tumor Suppressor Protein p53|DNA Damage|Cell Cycle|Ionizing Radiation|Serine|Signal Transduction|Chromosomal Instability | |
10766765 J. Biol. Chem. 2000 Chlorocebus aethiops|Animals|CMP-N-acetylneuraminate-poly-alpha-2,8-sialosyl sialyltransferase|Sia(alpha2,3)Gal(beta1,4)GlcNAc alpha-2,8-sialyltransferase|*Sialyltransferases|polysialic acid|*Neural Cell Adhesion Molecule|*Sialic Acids|*Oligosaccharides|Sialic Acid|Glycans|Amino Acid Sequence|Glycosylation|Transfection|COS Cells|Glycoproteins | |
10766785 J. Biol. Chem. 2000 Animals|Rats|Humans|*5'-Nucleotidase|*Inosine Monophosphate|nucleotidase|*Nucleotidases|Adenosine|Adenosine Monophosphate|*Cytosol|Adenosine Triphosphate|Inosine|Kinetics|*Biochemical Phenomena|*Cell Line|Guanosine|*Myoblast|Hypoxanthine|Pigeon | |
10766823 J. Biol. Chem. 2000 Animals|Rats|Chlorocebus aethiops|*Clathrin-Coated Vesicles|*trans-Golgi Network|*Phosphatidylinositol 3-Kinases|*Phosphoinositide 3-Kinase C2alpha|Clathrin|Golgi Apparatus|Brefeldin A|Intracellular Membranes|Endocytosis|gamma-Adaptin|Wortmannin|COS Cells|C2 Domains|Phosphatidylinositols|Immunofluorescence | |
10766826 J. Biol. Chem. 2000 Humans|MPO protein, human|*Peroxidase|*X-Rays|Hydrogen Peroxide|*Binding Sites|Bromides|Crystallography, X-Ray|Haem|Chlorides|Models, Molecular|*Radiography|Histidine | |
10767172 Mol. Genet. Metab. 2000 Animals|Humans|DMGDH protein, human|*Dimethylglycine Dehydrogenase|In Situ Hybridization, Fluorescence|*Mitochondrial Proteins|Sarcosine Dehydrogenase|Exons|Base Sequence|Amino Acid Sequence|cDNA|Chromosome Mapping|Cloning, Molecular|Oxidoreductases, N-Demethylating|Alleles|Sequence Analysis, DNA|Haplotypes|dimethylglycine|Sarcosine|Sequence Homology, Amino Acid | |
10767286 J. Biol. Chem. 2000 Cricetinae|Animals|*Peroxisomal Targeting Signal 2 Receptor|*Peroxisomal Targeting Signals|*Peroxin|*Peroxisomes|CHO Cells|Chinese Hamster|Peroxisome-Targeting Signal 1 Receptor|*Isoforms|*Membrane Transport Proteins|Receptors, Cytoplasmic and Nuclear|*Mammals|Membrane Proteins|*Translocation, Genetic|Amino Acid Sequence|Intracellular Membranes|Mutation | |
10767338 Hum. Mol. Genet. 2000 Humans|Rats|Animals|*Pemphigus, Benign Familial|*Mutations|Darier Disease|ATP2A2 protein, human|Sarcoplasmic Reticulum Calcium-Transporting ATPases|Mutations, Missense|Pedigree|Exons|Codon, Nonsense|Skin|Frameshift Mutation|Asian Continental Ancestry Group|ATP2C1 protein, human|Calcium-Transporting ATPases | |
10767346 Hum. Mol. Genet. 2000 Pregnancy|Humans|Child|Female|Intrahepatic Cholestasis of Pregnancy|*Mutation, Missense|Cholestasis, progressive familial intrahepatic 1|*Intrahepatic Cholestasis|multidrug resistance protein 3|ATP Binding Cassette Transporter, Subfamily B|Pregnancy Complications|*Heterozygote|ATP Binding Cassette Transporter, Subfamily B, Member 11|ATP-Binding Cassette Transporters|Mutation|Exon|Pedigree|Phenotype|Homozygote|Cholestasis|gamma-Glutamyltransferase|*Protein Transport | |
10767424 FEBS Lett. 2000 Animals|Humans|*Amiloride|Degenerin Sodium Channels|Acid Sensing Ion Channels|*Cloning, Molecular|Epithelial Sodium Channels|Ion Channel Gating|*Sodium|Protons|Amino Acid Sequence|Xenopus laevis|Neurons|cDNA|Oocytes|Sequence Homology, Amino Acid|*Intestine, Small | |
10769018 J. Cell Biol. 2000 PMC2175158 Animals|CTNNB1 protein, human|*beta Catenin|CREBBP protein, human|*CREB-Binding Protein|*Transcription Factors|Transcription Factors, LEF|Trans-Activators|Activation, Transcriptional|Xenopus laevis|Wnt Proteins|Nuclear Proteins|Xenopus Proteins|Binding Sites|Zebrafish Proteins|Cell Nucleus|Protein Binding|Promoter Regions, Genetic|*Gene Expression | |
10769020 J. Cell Biol. 2000 PMC2175154 ROCK1 protein, human|*rho-Associated Kinases|*Growth Cones|*Ephrin-A5|Y 27632|Amides|Axons|Pyridines|rho GTP-Binding Proteins|Neurites|Retinal Ganglion Cell|ADP Ribose Transferases|Signal Transduction Pathway|Botulinum Toxins|Eph Receptor Tyrosine Kinase|Retina|Enzyme Inhibitors|Cells, Cultured | |
10769135 Biochemistry 2000 Humans|*alpha-Amylase|*Catalytic Domain|*Pancreatic alpha-Amylases|*Kinetics|*Amylases|Acarbose|Hydrolysis|Oligosaccharides|Binding Sites|Trisaccharides|Catalysis|Protein Conformation|*Pancreas|Models, Molecular|Substrate Specificity|Crystallography, X-Ray|Maltose|*Mutagenesis | |
10769148 Biochemistry 2000 Humans|Rats|Mice|Animals|*Hydrolysis|*Esters|PNLIP protein, human|*Lipase|Carboxylester Lipase|Colipases|Carboxylic Ester Hydrolases|Triglycerides|Cholesterol Esters|Bile Acids and Salts|Pancreas|Vitamin A|Lipid Metabolism | |
10769163 Biochem. J. 2000 PMC1220996 Humans|Animals|LRP2 protein, human|*Low Density Lipoprotein Receptor-Related Protein-2|TYRP1 protein, human|*Membrane Glycoproteins|*Ligands|*Cytoplasm|*Carrier Proteins|Heymann Nephritis Antigenic Complex|*Cytosol|LDLR protein, human|Low Density Lipoprotein Receptor|Protein Binding|Amino Acid Sequence|Adaptor Proteins, Vesicular Transport|Adaptor Proteins, Signal Transducing|Tumor Suppressor Proteins|Endocytosis|Genes, Tumor Suppressor | |
10769175 Biochem. J. 2000 PMC1221008 Mice|Animals|Humans|*DNA, Complementary|*Arachidonic Acid|Mortierella|Fatty Acid Desaturases|Cloning, Molecular|Base Sequence|Sequence Alignment|Amino Acid Sequence|PCR|Nucleic Acid Amplification Techniques|Genome, Human | |
10770799 J. Exp. Med. 2000 PMC2193139 Humans|Mice|Animals|*Phosphatidylinositol 3-Kinase|Phosphatidylinositol 3-Kinases|Receptors, Antigen, B-Cell|*Signal Transduction|Adaptor Proteins, Signal Transducing|B-Lymphocytes|LNK protein, human|Germinal Center|*Antigen Receptor|Carrier Proteins|Lipoproteins|Plasma Membrane|Membrane Proteins|Phosphorylation|NFATC Transcription Factors|Phospholipase C gamma2|T-Lymphocytes|Phosphoinositides | |
10771479 J. Invest. Dermatol. 2000 Pregnancy|Humans|Epidermal Cells|Epidermis|*Epithelium|Cornified Envelope Proline-Rich Proteins|Keratinocytes|Amino Acid Sequence|Membrane Proteins|Protein Precursors|Cell Differentiation|Gene Expression|RNA, Messenger|*Protein Domains | |
10772654 J. Clin. Invest. 2000 PMC300829 Humans|Mice|Animals|*Monocytes|*Reactive Nitrogen Species|Hydrogen Peroxide|*CD36 Antigens|oxidized low density lipoprotein|Lipoproteins, LDL|Foam Cells|Scavenger Receptors, Class A|Macrophages|Receptors, Immunologic|Scavenger Receptors, Class B|Cholesterol|Cholesterol Esters|Macrophages, Peritoneal|Lipoprotein|Lipid Metabolism|Myeloperoxidase|Phospholipids | |
10772813 Exp. Cell Res. 2000 Humans|*Tumor Suppressor Protein p14ARF|*Cyclin-Dependent Kinase Inhibitor p16|*Cell Nucleolus|DNA, Neoplasm|nucleophosmin|Nuclear Proteins|Transcription, Genetic|DNA Methylation|Tumor Cell Lines|*Interphase | |
10773664 Cytogenet. Cell Genet. 2000 Adult|Humans|Swine|Animals|Glutamate formiminotransferase deficiency|*Glutamate Formimidoyltransferase|*Metabolism, Inborn Errors|formiminotetrahydrofolate cyclodeaminase|Ammonia-Lyases|Amino Acid Sequence|Cloning, Molecular|Golgi Apparatus|Liver|cDNA|Open Reading Frames|Protein Binding|Multienzyme Complexes | |
10775268 EMBO J. 2000 PMC302022 Animals|CTNNB1 protein, human|*beta Catenin|*Transcription Factors|p300-CBP-associated factor|*p300-CBP Transcription Factors|Trans-Activators|Activation, Transcriptional|Wnt Proteins|DNA-Binding Proteins|Reporter Gene|Xenopus Proteins|Xenopus laevis|Zebrafish Proteins|Signal Transduction|EP300 protein, human|E1A-Associated p300 Protein|Gene Expression Regulation|Binding Sites | |
10775272 EMBO J. 2000 PMC302013 EIF2AK4 protein, human|*Protein-Serine-Threonine Kinases|Saccharomyces cerevisiae|Saccharomyces cerevisiae Proteins|Phosphorylation|Peptide Elongation Factors|EIF-2|Protein Kinases|Gene Expression Regulation, Fungal|DNA-Binding Proteins|mRNA Translation|tRNA|Amino Acid Sequence|Binding Sites|Initiation Factor-2|Phenotype|Sequence Homology, Amino Acid|GCN2 protein, S cerevisiae | |
10775527 Am. J. Hum. Genet. 2000 PMC1378037 Humans|Animals|Saccharopinuria|*Hyperlysinemias|Lysine Ketoglutarate Reductase|saccharopine|Lysine|Amino Acid Metabolism, Inborn Errors|allysine|2-Aminoadipic Acid|Base Sequence|cDNA|Exons|Multienzyme Complexes|Mutations | |
10777207 Oncogene 2000 Humans|TP53 protein, human|*Tumor Suppressor Protein p53|*Introns|Receptors, TNF-Related Apoptosis-Inducing Ligand|TNF-Related Apoptosis-Inducing Ligand|Apoptosis|Apoptosis Regulatory Proteins|Doxorubicin|Tumor Cells, Cultured|Upregulation|Binding Sites|Promoter Regions, Genetic|DNA | |
10777476 J. Biol. Chem. 2000 *Peroxidase|*Nitrites|Redox|Kinetics|Hydrogen-Ion Concentration|Iron|Spectrophotometry|Neutrophils | |
10777492 J. Biol. Chem. 2000 Animals|Mice|Guanine Nucleotide Exchange Factors|ras Proteins|TYRP1 protein, human|*Membrane Glycoproteins|Amino Acid Sequence|G Proteins|GTPase-Activating Proteins|Cell Line|Cell Membrane|Sequence Homology, Amino Acid|3T3 Cells|Transfection | |
10777502 J. Biol. Chem. 2000 *Ligands|retinoic acid receptor gamma|*Receptor, Retinoic Acid|*Retinoids|NCOR1 protein, human|*Nuclear Receptor Co-Repressor 1|constitutive androstane receptor|Receptors, Cytoplasmic and Nuclear|DNA-Binding Proteins|Retinoid X Receptors|*Dimerization|Tretinoin|*DNA|Protein Binding|Transcription, Genetic|Transcriptional Activation|Protein Structure, Tertiary|Amino Acid Sequence | |
10777520 J. Biol. Chem. 2000 Humans|Rats|Animals|coenzyme Q10|ubiquinone Q3|*Ubiquinone|*Methyltransferases|Saccharomyces cerevisiae|Base Sequence|Genetic Complementation Test|Cloning, Molecular|Amino Acid Sequence|Escherichia coli|cDNA|Open Reading Frame|Mitochondria | |
10777541 J. Biol. Chem. 2000 Mice|Humans|Animals|*PPAR alpha|CYP7A1 protein, human|*Cholesterol 7-alpha-Hydroxylase|*Acids, Fatty|*Promoter Regions, Genetic|DNA-Binding Proteins|Receptors, Cytoplasmic and Nuclear|Receptors, Retinoic Acid|Binding Site|Retinoid X Receptors|Transcription, Genetic|Transcriptional Activation|Response Elements|Genes, Reporter|pirinixic acid|Pyrimidines|Transfections | |
10777549 J. Biol. Chem. 2000 Humans|glycollate oxidase|Alcohol Oxidoreductases|Alanine-glyoxylate transaminase|Transaminases|Amino Acid Sequence|Peroxisomes|Liver|Kinetics|Substrate Specificity|Sequence Alignment|glyoxylic acid|Glyoxylates|Cloning, Molecular|Sequence Homology, Amino Acid|Hydroxy Acids | |
10777559 J. Biol. Chem. 2000 Mice|Animals|Guanine Nucleotide Exchange Factor|ras Proteins|Mitogen-Activated Protein Kinases|Signal Transduction|rap1 GTP-Binding Proteins|Mitogen-Activated Protein Kinase Kinases|mitogen-activated protein kinase kinase kinase 11|MAP Kinase Kinase Kinases|Guanine Nucleotide-Releasing Factor 2|Enzyme Activation|Mitogen-Activated Protein Kinase 3|G Proteins|MAP Kinase Signaling System|Cell Line|src Homology Domains|Oncogenes|Fibroblasts | |
10777564 J. Biol. Chem. 2000 Animals|*Xenopus laevis|*Calcium-Calmodulin-Dependent Protein Kinase Type 2|Prospective Studies|CTNNB1 protein, human|beta Catenin|Xenopus Proteins|Wnt Proteins|Trans-Activators|WNT5A protein, human|Wnt-5a Protein|Frizzled Receptors|Signal Transduction|Zebrafish Proteins|Homeodomain Proteins|Transcription Factors|Body Patterning|Proto-Oncogene Proteins|Gene Expression Regulation, Developmental | |
10777568 J. Biol. Chem. 2000 Humans|Animals|Rats|Mice|exopolyphosphatase|*Acid Anhydride Hydrolases|diphosphoinositol polyphosphate phosphohydrolase|Amino Acid Sequence|Pyrophosphatases|*Catalysis|Isoforms|Substrate Specificity|Inositol Phosphates|Sequence Homology, Amino Acid|Kinetics|mRNA|Polyphosphates|Nucleotides | |
10777583 J. Biol. Chem. 2000 *Cytokine Receptor gp130|*Interleukin-6|*Suppressor of Cytokine Signaling Proteins|SH2 Domain-Containing Protein Tyrosine Phosphatases|Signal Transduction Pathways|SOCS3 protein, human|Suppressor of Cytokine Signaling 3 Protein|src Homology Domains|Transcription Factors|Protein Tyrosine Phosphatase, Non-Receptor Type 11|Tyrosine|Phosphorylation|Protein Tyrosine Phosphatase, Non-Receptor Type 6|Janus Kinase 1|Repressor Proteins|Membrane Glycoproteins|Antigens, CD|Protein Phosphatase 2 | |
10777614 J. Biol. Chem. 2000 Mice|Animals|*Calnexin|calreticulin, human|*Calreticulin|*Molecular Chaperone|*Endoplasmic Reticulum|Calcium-Binding Proteins|Ribonucleoproteins|Lectins|Protein Folding|Membrane Protein|Protein Binding|Glycoproteins|Cell Line | |
10777662 Genomics 2000 Male|Humans|Schizosaccharomyces pombe|Schizosaccharomyces pombe Proteins|*Cell Division|Cell Cycle|Cell Cycle Proteins|DNA Replication|Amino Acid Sequence|DNA Damage | |
10777694 Biochem. Biophys. Res. Commun. 2000 Animals|Humans|*Adrenoleukodystrophy|*ATP Binding Cassette Transporter, Subfamily D, Member 1|*Transporters, ABC|Peroxisomes|ATP Binding Cassette Transporter, Subfamily D|TYRP1 protein, human|*Membrane Glycoproteins|Membrane Proteins|Protein Binding|Intracellular Membranes|Yeast Two-Hybrid System|Dimerization | |
10779357 Mol. Cell. Biol. 2000 PMC85660 *Saccharomyces cerevisiae|frataxin|*HSP70 Heat-Shock Proteins|*Iron-Binding Proteins|*Mitochondria|Molecular Chaperones|Saccharomyces cerevisiae Proteins|Mitochondrial Proteins|Mitochondrial Membrane Transport Proteins|*Yeast, Dried|Heat-Shock Proteins|Carrier Proteins|Membrane Transport Proteins|Protein Binding|Adenosine Triphosphate|Iron | |
10779524 J. Biol. Chem. 2000 Chlorocebus aethiops|Animals|Mice|dectin 1|*DNA, Complementary|Lectins, C-Type|Northern Blotting|Amino Acid Sequence|Cloning, Molecular|mRNA|Recombinant Proteins|Dendritic Cells|Macrophage|Langerhans Cells|COS-1 Cells|Sequence Homology, Amino Acid|Spleen|Transfections|B Cells|Chromosome Mapping|Tissue Distribution | |
10779545 Proc. Natl. Acad. Sci. U.S.A. 2000 PMC25816 Humans|*Phosphorylation|*Arachidonate 5-Lipoxygenase|*Lipoxygenase|MAP-kinase-activated kinase 3|Protein-Serine-Threonine Kinases|Intracellular Signaling Peptides and Proteins|sodium arsenite|Sodium Compounds|N-Formylmethionine Leucyl-Phenylalanine|Arsenites|Mitogen-Activated Protein Kinases|Leukotrienes|Arachidonic Acid|Polymorphonuclear Leukocytes|p38 Mitogen-Activated Protein Kinases|Phorbol Myristate Acetate|Colony-Stimulating Factor, Granulocyte-Macrophage|Thapsigargin | |
10779566 Proc. Natl. Acad. Sci. U.S.A. 2000 PMC25794 Humans|Animals|Chick Embryo|5-methylcytosine-DNA glycosylase|*Chicken|*DNA Demethylation|Escherichia coli|DNA Glycosylase|MBD4 protein, human|*Endodeoxyribonucleases|*DNA|Base Sequence|Amino Acid Sequence|RNA, recombinant|RNA|Substrate Specificity|DNA Repair|Recombinant Proteins|Cloning, Molecular | |
10779773 J. Immunol. 2000 AKT1 protein, human|*Proto-Oncogene Proteins c-akt|*Cyclic Nucleotide Phosphodiesterases, Type 3|Phosphorylation|Phosphatidylinositol 3-Kinases|Wortmannin|Enzyme Activation|Cyclic AMP-Dependent Protein Kinases|Cyclic Nucleotide Phosphodiesterases, Type 4|IGF1 protein, human|Insulin-Like Growth Factor I|Cyclic AMP|Insulin|Adipocytes|*Thymidine | |
10779780 J. Immunol. 2000 Animals|Humans|Rabbits|complement factor H, human|*Complement Factor H|Convertase, C3-C5|Alternative Complement Pathway|Complement C3b|*Complement|Complement Activation|Protein Binding|Binding Sites|Erythrocytes|*Immune System | |
10781579 J. Biol. Chem. 2000 Humans|*Factor XIa|*Factor XIIa|*Thrombin|*Platelet Activations|kininogen 1, human|Kininogens|Blood Coagulation|Platelets|Prothrombin|Hemostatics|Fibrinogen|High Molecular Weight Kininogen|Dextran Sulfate|*Feedback | |
10781580 J. Biol. Chem. 2000 *Actins|*Arp2-3 Complex|WAS protein, human|*Wiskott-Aldrich Syndrome Protein|WASL protein, human|*Wiskott-Aldrich Syndrome Protein, Neuronal|GRB2 protein, human|*GRB2 Adaptor Protein|*Signal Transduction|Actin-Related Protein 3|Actin-Related Protein 2|Wiskott-Aldrich Syndrome Protein Family|Wiskott-Aldrich Syndrome|SH3 Domains|Nerve Tissue Proteins|Cell Motility|Protein Binding|Phosphatidylinositol 4,5-Diphosphate | |
10781587 J. Biol. Chem. 2000 Humans|Mice|Animals|*Chemokines|Chemokines, CC|Receptor, CCR10|Receptors, Chemokine|CCL27 protein, human|Chemokine CCL27|Cells, Epithelial|Amino Acid Sequence|Chemotaxis|Cloning, Molecular|CD8-Positive T-Lymphocytes|Cell Line|Transfections|RNA, Messenger|CCR10 protein, human|CCL28 protein, human|Ccr10 protein, mouse | |
10781589 J. Biol. Chem. 2000 Cattle|Animals|*Calmodulin|CAV1 protein, human|*Caveolin 1|Endothelial Cells|NOS3 protein, human|*Endothelial Nitric Oxide Synthase|Nitric Oxide Synthase|*HSP90 Heat-Shock Proteins|Phosphorylation|Endothelium, Vascular|Enzyme Activation|Vascular Endothelial Growth Factor A|Cells, Cultured | |
10781593 J. Biol. Chem. 2000 Mice|Animals|*Glycosylphosphatidylinositols|*Mannose|phosphorylethanolamine|*Ethanolamines|Amino Acid Sequence|Mannosyltransferases|Cloning, Molecular|*Phosphatidylethanolamines|Sequence Alignment|Membrane Proteins|Sequence Homology, Amino Acid|Transfection|Cell Membrane | |
10781596 J. Biol. Chem. 2000 Humans|Cricetinae|Animals|Adult|*Cloning, Molecular|carbohydrate sulfotransferases|*Sulfotransferases|Amino Acid Sequence|Base Sequence|cDNA|Sequence Alignment|CHO Cells|Chondroitin 6-Sulfate|Open Reading Frame|Oligosaccharides|Acetylgalactosamine|Sequence Homology, Amino Acid|Keratan Sulfate|Blotting, Northern|Substrate Specificity|Exon|Transfection | |
10781601 J. Biol. Chem. 2000 Humans|HNK-1 sulfotransferase|CHST11 protein, human|*Sulfotransferases|chondroitin 4-sulfotransferase|*Cloning, Molecular|cDNA|Amino Acid Sequence|Base Sequence|Iduronic Acid|Chromosome Mapping|Chondroitin Sulfate C|Sequence Homology, Amino Acid|Substrate Specificity|Acetylgalactosamine|Sulfates|Transfection | |
10781797 FEBS Lett. 2000 *Saposin C|*Phospholipids|*Glucosylceramidase|Sphingolipid Activator Proteins|*Anions|Glucosylceramides|Liposomes|Serine, Phosphatidyl|Phosphatidylinositol|Lysosomes|Membranes|Hydrogen-Ion Concentration|Glycoproteins | |
10783165 Genes Dev. 2000 PMC316544 BRCA1 protein, human|*BRCA1 Protein|DNA Repair|DNA Replication|Exodeoxyribonucleases|Endodeoxyribonucleases|*DNA|DNA-Binding Proteins|DNA Damage|Cell Cycle Proteins|RecQ Helicases|Saccharomyces cerevisiae Proteins|Nuclear Proteins|Cell Nucleus | |
10783391 J. Biol. Chem. 2000 Humans|Animals|*Transferases, Glutathione|Amino Acid Sequence|Sequence Alignment|Protein Conformation|Isoenzymes|Models, Molecular|Glutaredoxins|Glutathione|Sequence Homology, Amino Acid|Catalysis|Caenorhabditis elegans | |
10783894 Nature 2000 *Forkhead Transcription Factors|CDKN1B protein, human|*Cyclin-Dependent Kinase Inhibitor p27|PTEN protein, human|PTEN Phosphohydrolase|Proto-Oncogene Proteins c-akt|Phosphatidylinositol 3-Kinases|Cell Cycle|Proto-Oncogene Proteins|Cyclin-Dependent Kinases|Transcription, Genetic|*Cell Cycle Arrest|Signal Transduction|Retinoblastoma Protein|Genes, Tumor Suppressor|Cell Division|Forkhead Box Protein O1|Gene Expression Regulation | |
10786633 Biochim. Biophys. Acta 2000 Animals|Humans|*Drosophila|*Histones|*Transferases|KAT8 protein, human|Acetyltransferases, Histone|Dosage Compensation, Genetic|Drosophila Proteins|Saccharomyces cerevisiae Proteins|Acetylation|Nuclear Proteins|Amino Acid Sequence|Substrate Specificity|mof protein, Drosophila | |
10788335 Am. J. Hum. Genet. 2000 PMC1378052 Humans|Infant, Newborn|Aged|Congenital Disorder Of Glycosylation, Type IIB|*Congenital Disorders of Glycosylation|glucosidase I|alpha-Glucosidases|*Oligosaccharides|Glycosylation|Heterozygote|Carbohydrate Metabolism, Inborn Errors|Glycoprotein|Glucosidase|Glucose|Amino Acid Sequence|Mutations, Missense|Endoplasmic Reticulum|Cells, Cultured|Allele|Fibroblasts|Mutation | |
10788457 J. Biol. Chem. 2000 *Rod Photoreceptors|sodium-calcium exchanger 1|*Sodium-Calcium Exchanger|Rod Outer Segments|8-bromocyclic GMP|*Cyclic GMP|Ion Channel Gating|Cyclic Nucleotide-Gated Cation Channels|Calmodulin|Photoreceptors, Vertebrate|Cell Membrane|Calcium|Dimerization|Signal Transduction | |
10789724 Br. J. Cancer 2000 PMC2363384 Receptors, Transforming Growth Factor beta|Serine Threonine Kinase|Receptor, Transforming Growth Factor-beta Type II|TGFBR1 protein, human|Receptor, Transforming Growth Factor-beta Type I|*Carcinoma|TGFbeta|Mutation|SMAD4 protein, human|Smad4 Protein|SMAD2 protein, human|Smad2 Protein|DNA, Neoplasm|Polymorphism, Single-Stranded Conformational|Microsatellite Repeats|Polymerase Chain Reaction|Colon Cancers|Stomach Neoplasms | |
10790206 Hum. Mutat. 2000 Humans|*Galactosemias|Galactokinase|Mutations|Amino Acid Sequence|Mutation, Missense | |
10790433 J. Exp. Med. 2000 PMC2213442 Humans|Animals|*Phosphoproteins|*Adaptor Proteins, Signal Transducing|*Lymphocyte Activation|*Membrane Proteins|CSK protein, human|*Tyrosine-Protein Kinase CSK|src-Family Kinases|Phosphorylation|Receptors, Antigen, T-Cell|Membrane Microdomains|Tyrosine Kinase|*Glycosphingolipids|Signal Transduction|Jurkat Cells|Tyrosine | |
10790862 Neuroreport 2000 Animals|Humans|CLOCK protein, human|*CLOCK Proteins|*Phosphorylation|*Casein Kinase Iepsilon|Period Circadian Proteins|Nuclear Proteins|Cell Cycle Proteins|Drosophila|Protein Kinases|Circadian Rhythm|Cloning, Molecular | |
10791960 J. Biol. Chem. 2000 Male|Humans|*Seminal Vesicles|*Prostaglandin Endoperoxides|Cytochrome P450|PGH(2)|Aryl Hydrocarbon Hydroxylases|Hydroxylation|Microsomes|Prostaglandins|azo analog I|Prostaglandins H|Oxidation-Reduction|19-hydroxyprostaglandin E2|PGE2|Prostaglandins E|Alprostadil|19-hydroxyprostaglandin F|Dinoprost | |
10793135 Mol. Biol. Cell 2000 PMC14867 Humans|*Cdc20 Proteins|Anaphase Promoting Complex|Cell Cycle Proteins|Cdh1 Proteins|Ligase, Ubiquitin-Protein|Mitosis|CDH1 protein, human|*Cadherins|Saccharomyces cerevisiae Proteins|Anaphase|Cyclin B|*Antigens, CD|Phosphorylation|Cell Cycle|Telophase|CDC20 protein, human | |
10794676 Am. J. Physiol., Cell Physiol. 2000 Humans|Rats|Animals|*Dicarboxylic Acid Transporters|In Situ Hybridization, Fluorescence|Organic Anion Transporters, Sodium-Dependent|*Sodium|Symporters|Biological Transport|Membrane Proteins|dimethyl succinate|Succinates|cDNA|Xenopus laevis|Succinate|Kidney|Lithium|Amino Acid Sequence|Cloning, Molecular|Oocytes|*Genomics | |
10797013 Science 2000 *Proteasome Endopeptidase Complex|Ubiquitin|BIRC2 protein, human|Ubiquitin-Protein Ligases|Inhibitor of Apoptosis Proteins|X-Linked Inhibitor of Apoptosis Protein|Apoptosis|Cysteine Endopeptidases|*Ubiquitination|Protein Binding|Cell Death | |
10799505 J. Biol. Chem. 2000 Humans|*Nucleoside Diphosphate Kinase, Mitochondrial|NM23 Nucleoside Diphosphate Kinases|Nucleoside-Diphosphate Kinase|Transcription Factors|Amino Acid Sequence|Monomeric GTP-Binding Proteins|Mutagenesis, Site-Directed|Sequence Homology, Amino Acid|Phosphorylation|Transfections|Mitochondria | |
10799507 J. Biol. Chem. 2000 Animals|Rats|Humans|*Sphingosine-1-Phosphate Receptors|HEK293 Cells|sphingosine 1-phosphate|Lysophospholipids|Sphingosine|Receptors, Lysophospholipid|G-Protein-Coupled Receptors|Receptors, Cell Surface|Signal Transduction|Cloning, Molecular|Amino Acid Sequence|Transfections|Immediate-Early Proteins|Pertussis Toxin | |
10799510 J. Biol. Chem. 2000 *Lymphotoxin-beta|LTBR protein, human|*Lymphotoxin beta Receptor|TNFRSF14 protein, human|Herpesvirus Entry Mediator|*Apoptosis|TRAF3|Receptors, Tumor Necrosis Factor|Tumor Necrosis Factor Ligand Superfamily Member 14|Signal Transduction|Tumor Necrosis Factor-alpha|Cell Death|NF-kappa B|Ligands|Protein Binding | |
10799542 J. Biol. Chem. 2000 Mice|Animals|leptin receptor, human|*Receptors, Leptin|JAK2 protein, human|Janus Kinase 2|PTPN11 protein, human|Protein Tyrosine Phosphatase, Non-Receptor Type 11|Signal Transduction|STAT3 protein, human|STAT3 Transcription Factor|SH2 Domain-Containing Protein Tyrosine Phosphatases|Suppressor of Cytokine Signaling Proteins|Phosphorylation|GRB2 protein, human|GRB2 Adaptor Protein|Protein Tyrosine Phosphatase, Non-Receptor Type 6|Leptin|DNA-Binding Proteins|Tyrosine | |
10799570 J. Virol. 2000 PMC110848 *Coronavirus|*Coronavirus Infections|G protein, vesicular stomatitis virus|Viral Envelope Proteins|M protein, equine arteritis virus|Viral Membrane Proteins|Murine hepatitis virus|Spike Glycoprotein, Coronavirus|Virus Assembly|Membrane Glycoproteins|Virion|multiple myeloma M-proteins|*Myeloma Proteins|Mutagenesis|Amino Acid Sequence|Cell Line|Membrane Proteins|Antigens, Viral | |
10799894 J. Immunol. 2000 Mice|Animals|CTLA4 protein, human|*CTLA-4 Antigen|Lymphocyte Activation|CD28 Antigens|Abatacept|Antigens, CD|Immunoconjugates|Lymphoproliferative Disorders | |
10801053 J. Inherit. Metab. Dis. 2000 Infant, Newborn|Child|Humans|United States|*Biotinidase Deficiency|Biotinidase|Newborn Screening|DNA Mutational Analysis|Mutation|Amidohydrolases|DNA|Turkey | |
10801132 Nature 2000 Humans|*B-DNA|Rad30 protein|*DNA Polymerases|Thymine Dimers|DNA Replication|Mutagenesis|DNA Repair|DNA Damage|DNA|Base Pairing|Templates, Genetic|Mutations|Kinetics | |
10801319 Biochemistry 2000 Humans|*UDPglucose 4-Epimerase|*Catalytic Domain|UDP Galactose|UDP Glucose|X Ray Crystallographies|*Tyrosine|Protein Conformation|Galactosemia, Epimerase Deficiency|Binding Sites|NAD|Substrate Specificity|Models, Molecular|Hydrogen Bond|Escherichia coli | |
10801780 J. Biol. Chem. 2000 *eIF-2 Kinase|*Budding Yeast|Saccharomyces cerevisiae|Saccharomyces cerevisiae Proteins|*Amino Acids|Peptide Elongation Factors|Protein-Serine-Threonine Kinases|DNA-Binding Proteins|Eukaryotic Initiation Factor-2|Transcription Factor|Phosphorylation|Amino Acid Sequence|Phenotype|Protein Binding|GCN2 protein, S cerevisiae | |
10801827 J. Biol. Chem. 2000 Animals|*Peptide Elongation Factor Tu|elongation factor Ts|*tRNA, Amino Acyl|EEF1A1 protein, human|*Peptide Elongation Factor 1|Guanine Nucleotides|Ribosome|Guanosine Diphosphate|Guanosine Triphosphate|*Mitochondria|Escherichia coli|Kinetics | |
10801879 J. Biol. Chem. 2000 Humans|Animals|INSR protein, human|*Receptor, Insulin|*Drosophila|Insulin Receptor Substrate Proteins|Phosphorylation|Phosphotyrosine|Signal Transduction|*Antigens, CD|Phosphoproteins|SH2 Domain|Protein Binding|Phosphatidylinositol 3-Kinases|Insulin|GRB2 protein, human|GRB2 Adaptor Protein|Binding Sites|Carrier Proteins|Amino Acid Sequence | |
10802064 FEBS Lett. 2000 Humans|Mice|Animals|sphingosine kinase|HEK293 Cells|*Phosphotransferases (Alcohol Group Acceptor)|sphingosine 1-phosphate|Lysophospholipids|safingol|Sphingosine|erythro-(2R,3S)-sphingosine|Amino Acid Sequence|Sphingolipids|Transfections|Cloning, Molecular|Phosphorylation|Sequence Homology, Amino Acid|Kinetics | |
10802645 Nat. Genet. 2000 Humans|Hemochromatosis, type 2|*Hemochromatosis|Hemochromatosis Protein|Iron Overload|Receptors, Transferrin|Histocompatibility Antigens Class I|Mutation|Iron|Homozygote|Mutation, Nonsense|Membrane Proteins|TFR2 protein, human | |
10802669 Nat. Genet. 2000 Humans|ATM protein, human|*Ataxia Telangiectasia Mutated Proteins|*Phosphorylation|NBN protein, human|*Cell Cycle Proteins|*Nuclear Proteins|Ataxia Telangiectasia|MRE11 Homologue Protein|Tumor Suppressor Proteins|DNA-Binding Proteins|DNA Damage|Chromosome Breakage|Mutations|Serine|Ionizing Radiation|Chromosomal Instability|Radiosensitivity|Nijmegen Breakage Syndrome | |
10804184 Development 2000 Mice|Animals|*Genes, Homeobox|*Thyroid Gland|Prospective Studies|Endoderm|*Prosencephalon|Homeodomain Proteins|*Liver|Ectoderm|Transcription Factors|Body Patterning|Embryonic Induction|Gene Expression Regulation, Developmental|Mesoderm|Hepatocytes | |
10804209 J. Neurosci. 2000 PMC1237010 *Growth Cones|*Neural Cell Adhesion Molecule L1|Axons|Neural Cell Adhesion Molecules|Endocytosis|Cell Adhesion Molecules|Leukocyte L1 Antigen Complex|Membrane Glycoproteins|Ganglia, Spinal|Neurons|Cells, Cultured|Microtubules | |
10805725 Mol. Cell. Biol. 2000 PMC85707 Humans|*Phosphatidylinositol 3-Kinases|*Phosphatidylinositol|EGFR protein, human|Epidermal Growth Factor Receptor|*Kinases|*Growth Factor Receptors|Phosphoinositide 3-Kinase C2alpha|*Peptides|Epidermal Growth Factor|Phosphotyrosine|phosphatidylinositol 4-phosphate|Phosphatidylinositol Phosphates|Wortmannin|Signal Transduction|Cell Line|Tumor Cells, Cultured|Platelet-Derived Growth Factor|Inositol Phosphates | |
10805734 Mol. Cell. Biol. 2000 PMC85736 *Phosphorylation|PAK1 protein, human|PAK Kinases|SH3 Domain|Adaptor Proteins, Signal Transducing|Oncogene Proteins|Signal Transduction|Protein Binding|Amino Acid Sequence|Binding Sites|Serine|Cell Line | |
10805738 Mol. Cell. Biol. 2000 PMC85749 Humans|Mice|Animals|*Extracellular Signal Regulated Kinases|*Myogenesis|Myocyte Enhancer Factor 2A|MyoD Protein|Phosphorylation|p38 Mitogen-Activated Protein Kinases|MADS Domain Proteins|Cell Differentiation|Cell Lines|Transcription, Genetic|Myotube|Myoblasts|Signal Transduction|Chromatin | |
10805775 Proc. Natl. Acad. Sci. U.S.A. 2000 PMC25792 Cricetinae|Animals|*Sterol Regulatory Element Binding Protein 1|*Asparagine|*Proline|Nuclear Proteins|CCAAT-Enhancer-Binding Proteins|Sterol Regulatory Element Binding Protein 2|Membrane Proteins|Helix-Loop-Helix Motifs|Leucine Zippers|Amino Acid Sequence|Cell Nucleus|CHO Cells|Transfection|*Membrane|Peptide Hydrolases | |
10805787 Proc. Natl. Acad. Sci. U.S.A. 2000 PMC25817 STAT1 protein, human|*STAT1 Transcription Factor|Phosphorylation|src Homology Domain|Trans-Activators|Gene Activation|Amino Acid Sequence|Signal Transduction|*Cytokines|Protein Inhibitors of Activated STAT|*Ligases|Tyrosine|Transfection | |
10806096 J. Cell. Sci. 2000 postsynaptic density proteins|Nerve Tissue Proteins|Synapses|Carrier Proteins|Adaptor Proteins, Signal Transducing|Neurons|SH3 Domain|Cytoskeleton|Protein Binding|Amino Acid Sequence|Ankyrin Repeat|Two-Hybrid System Techniques|Brain|Sequence Homology, Amino Acid | |
10806194 J. Biol. Chem. 2000 Animals|Male|Chlorocebus aethiops|*Inositol Polyphosphate 5-Phosphatases|phosphatidylinositol 3-phosphate|Phosphatidylinositol Phosphates|Phosphoric Monoester Hydrolases|Amino Acid Sequence|Cytoplasmic Membrane|COS-7 Cells|Base Sequence|Inositol Phosphates|Cloning, Molecular|Proteins|Sequence Alignment|cDNA|Protein Binding|Golgi Apparatus|Cytosol|Substrate Specificity|Signal Transduction | |
10806474 Nat. Cell Biol. 2000 *Focal Adhesion Kinase|PTK2 protein, human|*Focal Adhesion Kinase 1|*Integrins|*Cell Migration|src Kinases|Phosphorylation|Signal Transduction|Epidermal Growth Factor|Cytoskeleton | |
10807566 Science 2000 Mice|Animals|*Circadian Clocks|Cryptochromes|ARNTL Transcription Factors|Period Circadian Proteins|CLOCK Proteins|Suprachiasmatic Nucleus|Photoreceptor Cells, Invertebrate|Nuclear Proteins|Trans-Activators|Drosophila Proteins|Eye Proteins|Cell Cycle Proteins|Circadian Rhythm|Transcription, Genetic|Gene Expression Regulation|*Mammals|Receptors, G-Protein-Coupled | |
10807576 Science 2000 Mice|Animals|TP53 protein, human|*Tumor Suppressor Protein p53|BCL2 protein, human|*Proto-Oncogene Proteins c-bcl-2|*Apoptosis Regulatory Proteins|Apoptosis|bcl-2 Homologous Antagonist-Killer Protein|CASP9 protein, human|Caspase 9|*Cell Death|Mitochondria|Cytochromes c|DNA Damage | |
10809667 Genes Dev. 2000 PMC316572 Male|Female|Mice|Animals|*Meiosis|MSH4 protein, human|*Cell Cycle Proteins|*Chromosome Pairing|*Chromosomes|Spermatocytes|DNA-Binding Proteins|Nuclear Proteins|Rad51 Recombinase|Adenosine Triphosphatases|Prophase I|MutS Proteins | |
10809722 J. Biol. Chem. 2000 Humans|matrix metalloproteinase 19|*Catalytic Domain|Kinetics|*Matrix Metalloproteinases, Secreted|Substrate Specificity|TIMP2 protein, human|TIMP-2|Stromelysin|Metalloendopeptidases|Amino Acid Sequence|TIMP1 protein, human|TIMP-1|prolylarginine|Dipeptides|glycyl-alanyl-leucine|Oligopeptides|Gelatinases|Recombinant Proteins | |
10809954 Immunology 2000 PMC2326990 Mice|Animals|invariant chain|*Antigen Presentation|*Cathepsin B|*Cathepsin D|*BALB C Mice|*Antigens, Differentiation, B-Lymphocyte|*Histocompatibility Antigens Class II|*Lysosomes|pepstatin|Pepstatins|Antigen-Presenting Cells|CD4-Positive T-Lymphocytes|*Immunizations|Th2 Cells|Leishmania major|Ovalbumin|*Vaccination|Cysteine Proteinase Inhibitors | |
10810289 J. Endocrinol. 2000 Humans|proinsulin-like growth factor II|IGF2 protein, human|*Insulin-Like Growth Factor II|*Cancer|IGFBP1 protein, human|*IGF-Binding Protein 1|IGFBP3 protein, human|Insulin-Like Growth Factor Binding Protein 3|IGFBP5 protein, human|Insulin-Like Growth Factor Binding Protein 5|IGF-Binding Proteins|Insulin-Like Growth Factor Binding Protein 2|Insulin-Like Growth Factor Binding Protein 4|Insulin-Like Growth Factor Binding Protein 6|Insulin-Like Growth Factor I|Protein Precursors|Protein Binding|Blotting, Western | |
10811639 J. Biol. Chem. 2000 Humans|Mice|Guinea Pigs|Animals|*cDNA|*Cloning, Molecular|Amino Acid Sequence|Nucleotide Sequence|trans-2-enoyl-CoA reductase (NADPH)|Oxidoreductases Acting on CH-CH Group Donors|Peroxisomes|Blotting, Northern|Fatty Acid Desaturases|*Mammals|*Oxidation-Reduction|cDNA Library|NADPH|Liver|Reductase|Kinetics|Escherichia coli|Acids, Fatty | |
1081164 Johns Hopkins Med J 1975 Humans|*Lymphocytes|B Cells|Receptors, Antigen, B-Cell|Immunoglobulin D|T Cells|Immunoglobulin M|Lymphocyte Activation|Leukemia, Lymphoid|Immunologic Deficiency Syndromes|Cell Membrane|*Biomarkers|Leukemia | |
10811803 J. Biol. Chem. 2000 Humans|*Phospholipase C gamma 1|*Tyrosine|GRB2 protein, human|*GRB2 Adaptor Protein|*Signal Transduction|*Phosphorylation|T-Cell Antigen Receptor|Phosphoproteins|src Homology Domains|Lymphocyte Activation|Carrier Proteins|Membrane Proteins|Jurkat Cells|*Mutations|Protein Binding|Binding Sites|LAT protein, Human herpesvirus 2|Viral Proteins | |
10811834 J. Cell Biol. 2000 PMC2174557 *Contactin 2|*Axons|NRCAM protein, human|*Cell Adhesion Molecules|Ng-CAM|Neurite|Cell Adhesion Molecules, Neuronal|*Spinal Cord|Growth Cone | |
10811835 J. Cell Biol. 2000 PMC2174566 Humans|*Integrin alpha6beta4|*Hemidesmosomes|*Tetraspanin 24|Integrin alpha3beta1|kalinin|Cell Adhesion Molecules|Cell Adhesion|Antigens, CD|Desmosomes|Integrin beta4|Keratinocytes|Antigens, Surface|TSPAN32 protein, human|*Tetraspanins|Cell Movement|Membrane Proteins|Skin|CD151 protein, human | |
10812249 Exp. Hematol. 2000 STAT5A protein, human|*STAT5 Transcription Factor|*Protein-Tyrosine Kinases|STAT1 protein, human|*STAT1 Transcription Factor|*Tumor Suppressor Proteins|Phosphorylation|Proto-Oncogene Proteins c-ets|Trans-Activators|Signal Transduction|Oncogene Proteins, Fusion|TYRP1 protein, human|*Membrane Glycoproteins|Repressor Proteins|Leukemia, Myelomonocytic, Chronic|Cell Transformation, Neoplastic|Interleukin-3|Cell Division | |
10812968 Pharm Acta Helv 2000 Humans|Mice|Animals|Adult|*Ciliary Neurotrophic Factor|Receptor, Ciliary Neurotrophic Factor|Cytokine Receptor gp130|Leukemia Inhibitory Factor Receptor alpha Subunit|Signal Transduction|Receptors, OSM-LIF|Receptors, Cytokine|*Protein Binding|LIF protein, human|Inhibitory Factor, Leukemia|STAT3 Transcription Factor|Phosphorylation|Interleukin 6|Cell Survival|Motor Neurons|Membrane Glycoproteins|Cells, Glial|Cell Differentiation | |
10814706 Glycobiology 2000 Humans|*Fucosyltransferases|Exons|cDNA|*Promoter Regions, Genetic|Base Sequence|Cloning, Molecular|GDP Fucose|Open Reading Frames|*Computational Biology|Genome|DNA|Reporter Gene|Genomics | |
10818110 J. Biol. Chem. 2000 Humans|HeLa Cells|*Protein A|*Endosome|rab5 Protein|Membrane Fusion|Endocytosis|Vesicular Transport Proteins|Carrier Proteins|GTPase|Guanosine Triphosphate|Luminescent Proteins|Membrane Proteins|Green Fluorescent Proteins|Transfections|*Membrane | |
10818153 J. Neurosci. 2000 PMC6772629 Mice|Humans|Animals|*Mitogen-Activated Protein Kinases|*Signal Transduction|*Axon Outgrowth|MAPK3 protein, human|Extracellular Signal Regulated Kinase 1|Neurites|*Endocytosis|Neurons|pp60 c-src|Phosphorylation|MAPK Kinases|Tyrosine Kinase|MAP Kinase Signaling System|Protein-Serine-Threonine Kinases|Neural Cell Adhesion Molecule L1|Neuroblastoma|Cells, Cultured|Cell Line | |
10821277 Nature 2000 *Phosphorylation|Activation, Transcriptional|Acetyltransferase, Histone|*Acetylation|Transcription, Genetic|Cyclic AMP Response Element-Binding Protein|Chromatin|Saccharomyces cerevisiae Proteins|Activating Transcription Factor 2|Transfection|Histone H2b|Amino Acid Sequence|Cyclic AMP Response Element-Binding Protein A | |
10821868 J. Biol. Chem. 2000 Humans|Male|Chlorocebus aethiops|Animals|Rats|Mice|*Sugar|Glucose Transporter|Monosaccharide Transport Proteins|Testis|mRNA|Amino Acid Sequence|*Biological Transport|cDNA|*Facilitated Diffusion|Transfections|COS-7 Cells|Cytochalasin B|Glucose | |
10822011 J. Steroid Biochem. Mol. Biol. 2000 Humans|Animals|Rabbits|estrophilin|*Receptors, Estrogen|geldanamycin|Lactams, Macrocyclic|*HSP90 Heat-Shock Proteins|Benzoquinones|*Protein Binding|Molecular Chaperone|Saccharomyces cerevisiae|Quinones|Signal Transduction|Carrier Proteins|Ligands | |
10822173 Cell. Signal. 2000 *Phosphatidylinositol|*Fusion Proteins, bcr-abl|*Phosphoproteins|*Phosphoric Monoester Hydrolases|Leukemia, Myelogenous, Chronic, BCR-ABL Positive|SH2 Domain|INPP5D protein, human|*Phosphatidylinositol-3,4,5-Trisphosphate 5-Phosphatases|Adaptor Proteins, Signal Transducing|Phosphorylation|Phosphotyrosine|Signal Transduction|Phosphatidylinositol 3-Kinases|Amino Acid Sequence|*Polyphosphates|*Inositol Phosphates | |
10822380 Oncogene 2000 *Leukemia, Erythroblastic, Acute|*Erythropoiesis|*Friend murine leukemia virus|*Signal Transduction Pathways|EPO protein, human|Erythropoietin|*Cell Differentiation|Receptors, Erythropoietin|Phosphorylation|Trans-Activators|Erythroid Precursor Cells|Stem Cell Factor|Spleen Focus-Forming Virus|Janus Kinase 2|STAT5 Transcription Factor|Cell Division|Protein Binding|fli-1 Transcription Factor | |
10822381 Oncogene 2000 Humans|SMAD2 protein, human|*Smad2 Protein|SMAD4 protein, human|*Smad4 Protein|Transforming Growth Factor beta|Activation, Transcriptional|Smad3 Protein|Trans-Activators|Signal Transduction|Transcription, Genetic|SERPINE1 protein, human|Plasminogen Activator Inhibitor 1|Promoter Regions, Genetic|Binding Sites|Genes, Tumor Suppressor|*Lung Cancers | |
10823823 J. Biol. Chem. 2000 Humans|CASP3 protein, human|*Caspase 3|adducin|*Cisplatin|*Phosphorylation|aspartyl-aspartic acid|*Capping Protein, Actin|*Serine|*Calmodulin-Binding Proteins|benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone|Amino Acid Chloromethyl Ketones|Caspases|isoleucylvaline|*Dipeptides|arginylvaline|Caspase Inhibitors|Apoptosis|Caspase 6 | |
10823827 J. Biol. Chem. 2000 Animals|Humans|Rats|*Glutamine|*Sodium|Amino Acids|Biological Transport|*Genome|Amino Acid Transport Systems, Neutral|Carrier Proteins|Histidine|Xenopus laevis|Amino Acid Sequence|Oocytes|Active Transport|Asparagine|*Genomics|*Ions|Cloning, Molecular|*Ion Transport|Alanine | |
10823831 J. Biol. Chem. 2000 VHL protein, human|*Von Hippel-Lindau Tumor Suppressor Protein|Transcription Factors|*Ubiquitylation|*Hypoxia|DNA-Binding Proteins|Nuclear Proteins|Ligases|Proteasome|Ubiquitins|Protein Structure, Tertiary|Trans-Activators|Protein Binding|Oxygen|Transcriptional Activation|Renal Cell Carcinoma|Mutations|*Complement Factor B | |
10823841 J. Biol. Chem. 2000 STAT5A protein, human|*STAT5 Transcription Factor|*src Homology Domains|*Point Mutation|*Tumor Suppressor Proteins|DNA-Binding Proteins|Trans-Activators|Phosphorylation|Phosphotyrosine|IL3 protein, human|Interleukin-3|Tyrosine|Milk Proteins | |
10823918 Proc. Natl. Acad. Sci. U.S.A. 2000 PMC18615 Animals|Adult|Humans|*Retinoic Acid 4-Hydroxylase|*Cytochrome P450|Tretinoin|Retinoids|*Oxidation-Reduction|Cloning, Molecular|Amino Acid Sequence|Sequence Alignment|*Cerebellum|Zebrafish|*Biochemical Phenomena | |
10823942 Proc. Natl. Acad. Sci. U.S.A. 2000 PMC18530 Animals|Rats|*Sphingomyelin Phosphodiesterase|*Magnesium|Phylogeny|*Mammals|Sphingomyelins|Cloning, Molecular|Ceramides|Amino Acid Sequence|Cell Lines|Signal Transduction|*Esterases|*Brain|Golgi Apparatus|Serine, Phosphatidyl|Hydrogen-Ion Concentration | |
10824116 Eur. J. Biochem. 2000 Rats|Male|Mice|Animals|Humans|N-acetylglucosamine kinase|*Cloning, Molecular|*Phosphotransferases (Alcohol Group Acceptor)|Amino Acid Sequence|cDNA|Base Sequence|Gene Library|mRNA|Open Reading Frame|Sequence Alignment|Sequence Homology, Amino Acid|Escherichia coli|Testis|Expressed Sequence Tags|Organ Specificity | |
10825151 J. Biol. Chem. 2000 Animals|*Hedgehog Proteins|Drosophila Proteins|DNA-Binding Proteins|Transcription Factors|Drosophila|Drosophila melanogaster|Signal Transduction|Smoothened Receptor|Protein-Serine-Threonine Kinases|*Cytoplasm|Kinesin|Repressor Proteins|Cell Nucleus|Phosphorylation|Protein Binding | |
10825200 Mol. Cell. Biol. 2000 PMC85804 *Interleukin-2|JAK3 protein, human|*Janus Kinase 3|*Signal Transduction|JAK1 protein, human|Janus Kinase 1|STAT5A protein, human|STAT5 Transcription Factor|Phosphorylation|Receptors, Interleukin-2|STAT3 protein, human|STAT3 Transcription Factor|Tumor Suppressor Proteins|Trans-Activators|DNA-Binding Proteins | |
10825208 Mol. Cell. Biol. 2000 PMC85812 Humans|Mice|Animals|*Hepatocyte Nuclear Factor 6|*Islets of Langerhans|*Cell Differentiation|Transcription Factors|Homeodomain Proteins|Pancreas|Trans-Activators|Basic Helix-Loop-Helix Transcription Factors|Gene Expression Regulation, Developmental|Insulin-Secreting Cells|Promoter Regions, Genetic|*Neuroendocrine Cells|Nerve Tissue Proteins|Liver | |
10825291 J. Cell. Sci. 2000 *Golgi Apparatus|*Endoplasmic Reticulum|Vesicular Transport Proteins|Protein Transport|Membrane Proteins|Biological Transport|Transport Vesicles|Carrier Proteins|Saccharomyces cerevisiae Proteins|Phosphoproteins|Coat Protein Complex I | |
10826704 DNA Seq. 2000 Humans|*Serum Response Element|*Promoter Regions, Genetic|Binding Sites|Immediate-Early Proteins|Transcription, Genetic|Gene Expression Regulation|Response Elements|Zinc Finger|Early Growth Response Protein 1|Cyclic AMP Response Element-Binding Protein|Base Sequence|Map Kinase Kinase|Signal Transduction | |
10827079 J. Biol. Chem. 2000 Humans|Mice|Animals|DNAJB1 protein, human|*HSP40 Heat-Shock Proteins|*Molecular Chaperones|*Endoplasmic Reticulum|Heat-Shock Proteins|HSP70 Heat-Shock Proteins|Protein Folding|Carrier Proteins|Protein Transport|Amino Acid Sequence|Protein Biosynthesis|Adenosine Triphosphatases|Protein Binding | |
10827188 J. Biol. Chem. 2000 Animals|Humans|inositol hexakisphosphate kinase|*Saccharomyces cerevisiae|*Vacuoles|*Phosphotransferases (Phosphate Group Acceptor)|inositol pentaphosphate|Inositol Phosphates|1-diphosphoinositol pentakisphosphate|Saccharomyces cerevisiae Proteins|*Yeast, Dried|*Catalysis|Phosphotransferases (Alcohol Group Acceptor)|Kinetics|Sequence Homology, Amino Acid|Polyphosphates|Amino Acid Sequence|Inositol Hexakisphosphate | |
10827953 Science 2000 Humans|CDC25A protein, human|*cdc25 Phosphatases|CDK2 protein, human|Cyclin-Dependent Kinase 2|*DNA Damage|S Phase|Protein Kinase, Chk1|Phosphorylation|Cyclin-Dependent Kinases|G1 Phase|Protein Kinases|DNA Repair|Cell Cycle|Cyclin E|Signal Transduction|Ubiquitin|Ionizing Radiation | |
10828066 J. Biol. Chem. 2000 Humans|*Tryptophan-tRNA Ligase|Amino Acid Sequence|Protein Binding|Kinetics|Models, Molecular|Sequence Homology, Amino Acid|Tryptophan|Histidine | |
10828826 J. Mol. Endocrinol. 2000 Humans|*Oestradiol|*Transcriptional Activation|TGFA protein, human|*Transforming Growth Factor alpha|*Estrogens|estrogen receptor alpha, human|Estrogen Receptor alpha|Receptors, Estrogen|*Response Element|Promoter Regions, Genetic|Sp1 Transcription Factor|Transfection|Base Sequence|Binding Sites|Cathepsin D | |
10828887 Oncogene 2000 Animals|*Proteasome Endopeptidase Complex|*Cell Division|CDC25A protein, human|*cdc25 Phosphatases|Ubiquitins|Cell Cycle|Ubiquitin|Cysteine Endopeptidases|myc Gene|Cytoplasm|Tumor Cells, Cultured|Cell Differentiation | |
10828989 Biochemistry 2000 Animals|*Bacillus anthracis|edema factor|anthrax toxin|*Bacterial Toxins|*Antigens, Bacterial|Viper Venoms|Anthrax|*Anthrax Vaccines|*Exotoxins|Models, Molecular|His-His-His-His-His-His|Oligopeptides|Histidine | |
10830164 Cell 2000 Humans|*Ryanodine Receptor Calcium Release Channel|tacrolimus binding protein 1B|*Calcium|*Phosphorylation|*FK506 Binding Proteins|*Calcium Signaling|*Heart Failure|Sarcoplasmic Reticulum|Cardiac Muscle|Protein Kinase A | |
10830841 J. Inorg. Biochem. 2000 Animals|zinc thionein|*Metallothionein|*Copper|*Circular Dichroism|*Mercury|Zinc|Cadmium|*Kinetics|Metals|Binding Sites|Mammals|Liver|Electrospray Ionization Mass Spectrometry | |
10830966 Nature 2000 Humans|*Calpain|Amyloid beta-Peptides|CDK5 protein, human|Cyclin-Dependent Kinase 5|Neurons|*Neurotoxicity Syndromes|tau Proteins|Alzheimer Disease|Phosphorylation|Cells, Cultured|Brain|Signal Transduction|Apoptosis | |
10831586 J. Biol. Chem. 2000 *Phosphorylation|*Serine|CDKN1B protein, human|*Kip1 Protein, p27|Cyclin-Dependent Kinases|Cyclin|Cell Cycle|Cyclin-Dependent Kinase 2|M Phase|G1 Phase|Microtubule-Associated Proteins|Proliferating Cell Nuclear Antigen|*Protein Stability|Cell Line | |
10831588 J. Biol. Chem. 2000 Humans|Mice|Animals|*Chloride Channels|Bartter syndrome, type 3|Bartter Syndrome|*Kidney Diseases|Kidney|Xenopus laevis|Nephron|Chlorides|Anion Transport Proteins|Membrane Proteins|Point Mutations|Patch-Clamp Techniques|Mutations|Oocytes|Cell Line | |
10831612 J. Cell Biol. 2000 PMC2174823 *Tubulin|*ADP-Ribosylation Factor|Microtubules|Microtubule-Associated Proteins|tubulin-specific chaperone C|Molecular Chaperones|Schizosaccharomyces pombe Proteins|GTP-Binding Proteins|Protein Folding|GTPase Activating Protein|Dimerization | |
10831834 Gene 2000 Humans|Animals|*Transducin|gro protein, Drosophila|Repressor Proteins|Basic Helix-Loop-Helix Transcription Factors|Corepressors|Transcription, Genetic|Histone Deacetylase|Cell Nucleus|TYRP1 protein, human|*Membrane Glycoproteins|Drosophila|*Regulatory Sequences, Nucleic Acid|groucho protein, Drosophila|Rpd3 protein, Drosophila | |
10832746 Pediatr. Res. 2000 Male|Infant, Newborn|Humans|Female|*Isoleucine|2-Methylbutyryl-CoA Dehydrogenase Deficiency|*Coenzyme A|Amino Acid Metabolism, Inborn Errors|Base Sequence|Oxidoreductases Acting on CH-CH Group Donors|Neonatal Screening|Amino Acids|2-methylbutyrylglycine|Glycine | |
10833429 Biochem. Biophys. Res. Commun. 2000 Humans|*mtDNA|*Glutathione|*Mitochondria|glutathione peroxidase GPX1|Glutathione Peroxidase|Oxidative Stress|DNA Damage|barley peroxidase|*Peroxidases|Catalase|Hydrogen Peroxide|Menadione | |
10834843 Science 2000 Saccharomyces cerevisiae|DNA Replication|Saccharomyces cerevisiae Proteins|Cell Cycle Proteins|Minichromosome Maintenance Complex Component 4|Chromosomal Proteins, Non-Histone|Minichromosome Maintenance Complex Component 7|Chromosomes, Fungal|DNA, Fungal|DNA-Binding Proteins|Nuclear Proteins|Minichromosome Maintenance Complex Component 6|Cell Cycle|G1 Phase|Cell Nucleus|DNA Helicases | |
10835346 EMBO J. 2000 PMC212771 Cricetinae|Animals|Humans|*Mannose|dolichyl-phosphate beta-D-mannosyltransferase|*Mannosyltransferases|Dolichol Monophosphate Mannose|Amino Acid Sequence|Glycosylphosphatidylinositols|Carrier Proteins|Cloning, Molecular|Endoplasmic Reticulum|Sequence Homology, Amino Acid|Saccharomyces cerevisiae|CHO Cells|Phosphates|Dolichols|DPM3 protein, human|Membrane Proteins | |
10835426 J. Biol. Chem. 2000 Animals|Rats|Guanine Nucleotide Exchange Factor|ras Proteins|rap1 GTP-Binding Proteins|PC12 Cells|Proto-Oncogene Proteins c-raf|Mitogen-Activated Protein Kinases|Enzyme Activation|G Proteins|Transfection|Substrate Specificity|DNA, Complementary|Amino Acid Sequence | |
10835430 J. Biol. Chem. 2000 Humans|Mice|Animals|ERN1 protein, human|Endoribonucleases|Serine Threonine Protein Kinases|*Dimerization|Saccharomyces cerevisiae|*Endoplasmic Reticulum|Signal Transduction|eIF-2 Kinase|Sequences, Amino Acid|Unfolded Protein Response|Membrane Proteins|*Ligands|Protein Folding|Saccharomyces cerevisiae Proteins|Endoplasmic Reticulum Stress|Phosphorylation|Protein Biosynthesis|Membrane Glycoproteins | |
10835642 Nat. Genet. 2000 *Pseudoxanthoma Elasticum|*ATP-Binding Cassette Transporters|ABCC6 protein, human|Multidrug Resistance-Associated Proteins|*Mutations|DNA Mutational Analysis|Pedigree|Homozygote|Multidrug Resistance|Chromosome Mapping|Heterozygote|Haplotypes|Skin|Phenotype | |
10837024 Genes Dev. 2000 PMC316657 *Endothelium, Vascular|Receptors, Notch|*Protein Binding|Intracellular Signaling Peptides and Proteins|Membrane Proteins|Transcription Factors|Signal Transduction|Endothelial Cell|Calcium-Binding Proteins|In Situ Hybridization|Vascular Endothelial Growth Factor A | |
10837247 Curr. Biol. 2000 Humans|CASP8 protein, human|*Caspase 8|*NF-kappa B|FADD protein, human|Fas-Associated Death Domain Protein|*Signal Transduction|FASLG protein, human|Fas Ligand Protein|CASP8 and FADD-Like Apoptosis Regulating Protein|RELA protein, human|*Transcription Factor RelA|fas Receptor|Caspases|Apoptosis|Caspase 9|*Pathways, ERK|Jurkat Cells | |
10837478 J. Biol. Chem. 2000 Humans|Mice|Animals|lipoxin A4|*Lipoxins|leukotriene B4 12-hydroxydehydrogenase|*Oxidoreductases|CBR1 protein, human|*Alcohol Oxidoreductases|15 Oxoprostaglandin 13 Reductase|*Inflammation|Receptors, Lipoxin|Receptors, Formyl Peptide|Leukotriene B-4|Polymorphonuclear Leukocytes|15-hydroxyprostaglandin dehydrogenase|Hydroxyprostaglandin Dehydrogenases|Recruitment, Neutrophil|Eicosanoids|Hydroxyeicosatetraenoic Acids|Prostaglandins | |
10837493 J. Biol. Chem. 2000 Humans|Cricetinae|Animals|Rats|CHO Cells|Cricetulus|Saccharomyces cerevisiae|*Mitochondria|Saccharomyces cerevisiae Proteins|Genetic Complementation Test|ATP-Binding Cassette Transporters|DNA, Mitochondrial|Iron|Cytosol|Amino Acid Sequence|DNA Damage|*Homeostasis|Biological Transport|Adenosine Triphosphate | |
10838074 FEBS Lett. 2000 Humans|*Phosphorylation|*MAP Kinase Kinase Kinases|Adaptor Proteins, Signal Transducing|Mitogen-Activated Protein Kinases|Intracellular Signaling Peptides and Proteins|MAPK, p38|c-jun N-Terminal Kinase|Signal Transduction|NF-kappa B|Carrier Proteins|MAP Kinase Signaling System|Protein Binding|Enzyme Activation|HeLa Cells|TAB1 protein, human | |
10838083 FEBS Lett. 2000 Animals|Axn protein, Drosophila|*Axin Protein|*Drosophila Proteins|CTNNB1 protein, human|beta Catenin|Drosophila|Wnt1 Protein|Trans-Activators|Armadillo Domain Proteins|Transcription Factors|Signal Transduction|Wnt Proteins|Adaptor Proteins, Signal Transducing|Proto-Oncogene Proteins|Phosphoproteins|Repressor Proteins|Carrier Proteins|Homeodomain Proteins | |
10839362 Neuron 2000 *Receptor, ErbB-4|*Synapses|*Disks Large Homolog 4 Protein|*Signal Transduction|Neuregulin-1|Neurons|ErbB Receptors|*Transcription Factors|Nerve Tissue Proteins|Intracellular Signaling Peptides and Proteins|Long-Term Potentiation|Synaptic Plasticity|Membrane Proteins|Mitogen-Activated Protein Kinases|Synaptic Transmission|Hippocampus|Carrier Proteins|Cells, Cultured | |
10839978 Biochem. J. 2000 PMC1221089 *Retinoid Binding Proteins|*Retinoids|Vitamin A|Protein Conformation|Ligands | |
10842173 J. Biol. Chem. 2000 Humans|*Glucuronosyltransferase|*Cysteine|*Dimerization|UDP Glucuronic Acid|Mutagenesis, Site-Directed|Amino Acid Sequence|Substrate Specificity|Binding Sites|Glycosaminoglycans|Kinetics|Models, Molecular|Alanine | |
10842181 J. Biol. Chem. 2000 *Neuropilin-1|VEGFA protein, human|*Vascular Endothelial Growth Factor A|FLT1 protein, human|*VEGFR-1|*Vascular Endothelial Growth Factors|Receptors, Vascular Endothelial Growth Factor|KDR protein, human|Kinase Insert Domain Receptor|Receptor Protein-Tyrosine Kinases|Receptors, Growth Factor|Signal Transduction|Protein Isoforms|Proto-Oncogene Proteins|Neovascularization, Pathologic|Protein Binding|Nerve Tissue Proteins|Endothelium, Vascular | |
10843389 Immunity 2000 Animals|*Drosophila|*Antifungal Agents|*Transcription Factors|Drosophila Proteins|DNA-Binding Proteins|Drosophila melanogaster|NF kB|Toll-Like Receptors|Nuclear Proteins|Genes, Insect|Gene Expression Regulation|Innate Immune Response|Phosphoproteins|Signal Transduction|*Anti-Bacterial Agents|Gram Positive Bacteria|Larvae|Membrane Glycoproteins | |
10843999 J. Biol. Chem. 2000 Mice|Animals|Humans|*Sterol Regulatory Element Binding Proteins|*Acetyl Coenzyme A|Nuclear Proteins|CCAAT-Enhancer-Binding Proteins|Helix-Loop-Helix Motifs|*Acetate-CoA Ligase|Leucine Zippers|Sterol Regulatory Element Binding Protein 2|Sterol Regulatory Element Binding Protein 1|Isoforms|Amino Acid Sequence|mRNA|Transfection|Cell Line|Sterols | |
10846107 J. Virol. 2000 PMC112122 INS1 protein, influenza virus|*Viral Nonstructural Proteins|Influenza A virus|Virus Replication|eIF-2 Kinase|Influenza, Human|Cell Line|Double-Stranded RNA|Immunity, Innate | |
10846156 Science 2000 *Kinesin|NR2B NMDA receptor|*Receptors, N-Methyl-D-Aspartate|*Biological Transport|Molecular Motor Proteins|Microtubules|Neurons|TYRP1 protein, human|*Membrane Glycoproteins|Protein Transport|Protein Binding|Adaptor Proteins, Signal Transducing|Cells, Cultured | |
10846164 Science 2000 Animals|*Drosophila|*Frizzled Receptors|*Signal Transduction|Drosophila Proteins|Wnt1 Protein|CTNNB1 protein, human|beta Catenin|Receptors, G-Protein-Coupled|Proto-Oncogene Proteins|Body Patterning|Wnt Proteins|Dishevelled Proteins|Wings, Animal|Phosphoproteins|Adaptor Proteins, Signal Transducing|Membrane Proteins|Trans-Activators|Gene Expression Regulation, Developmental | |
10846177 J. Biol. Chem. 2000 Humans|*Phosphorylation|*Threonine|CDC7 protein, human|Cell Cycle Proteins|*Cyclin-Dependent Kinases|CDK2 protein, human|Cyclin-Dependent Kinase 2|MCM2 protein, human|Minichromosome Maintenance Complex Component 2|Nuclear Proteins|S Phase|Cell Cycle|DNA-Binding Proteins|Cyclin A|Cell Division|Chromatin|CCNE1 protein, human|Cyclin E | |
10848605 Mol. Cell. Biol. 2000 PMC85918 Animals|Chlorocebus aethiops|*Phosphorylation|*Receptors, Eph|*Tyrosine|Kinetics|EPHB2 protein, human|Receptor, EphB2|*Cell Membrane|src Homology Domains|Amino Acid Sequence|Signal Transduction|Phenylalanine|Binding Sites|Neurons|COS Cells|Receptor, EphA4|Neurites|Amino Acids | |
10848614 Mol. Cell. Biol. 2000 PMC85940 Mice|Humans|Animals|HEK293 Cells|*Casein Kinase Iepsilon|Nuclear Protein|*Cell Nucleus|Transcription Factors|Period Circadian Proteins|Cell Cycle Proteins|Circadian Rhythm|Phosphorylation|*Mammals|Nuclear Localization Signal|Cytoplasm|Protein Kinases|Amino Acid Sequence | |
10849428 J. Biol. Chem. 2000 *Interleukin-2|IL15 protein, human|*Interleukin-15|*Lymphocyte Activation|*Cytokines|GAB2 protein, human|*Adaptor Proteins, Signal Transducing|*Signal Transduction|IL2RG protein, human|*Interleukin Receptor Common gamma Subunit|Phosphoproteins|PTPN11 protein, human|Protein Tyrosine Phosphatase, Non-Receptor Type 11|Phosphorylation|IL2RB protein, human|Interleukin-2 Receptor beta Chain|Mitogen-Activated Protein Kinases|IL2RA protein, human | |
10849438 J. Biol. Chem. 2000 Humans|*Interleukin-2|*CD28 Antigens|*Phosphorylation|VAV1 protein, human|*Proto-Oncogene Proteins c-vav|*T Cell Receptor|JNK Mitogen-Activated Protein Kinases|Cell Cycle Proteins|Mitogen-Activated Protein Kinases|Proto-Oncogene Proteins|Signal Transduction|Transcription Factors|Enzyme Activation|Jurkat Cells|Transcription, Genetic|Lymphocyte Activation|p38 Mitogen-Activated Protein Kinases|Tyrosine | |
10851062 Oncogene 2000 *Phosphorylation|*Serine|Trans-Activators|Transductions, Signal|STAT1 Transcription Factor|Gene Expression Regulation|Amino Acid Sequence|Cell Nucleus|Tyrosine|Dimerization|Transfection|Sequence Homology, Amino Acid | |
10851237 J. Biol. Chem. 2000 Humans|SMN Complex Proteins|*Muscular Atrophy, Spinal|Ribonucleoproteins, Small Nuclear|RNA-Binding Proteins|*RNA|Nuclear Proteins|Nerve Tissue Proteins|Cyclic AMP Response Element-Binding Protein|Protein Binding|Cytoplasm|Amino Acid Sequence|Cell Nucleus|Arginine|HeLa Cells | |
10851239 J. Biol. Chem. 2000 Humans|cysteinyl leukotriene receptor 2|HEK293 Cells|leukotriene D4 receptor|*Receptors, Leukotriene|BAY u9773|SRS-A|Leukotriene D4|cysteinyl-leukotriene|Leukotrienes|Leukotriene C4|Leukotriene Antagonists|LTE4|Muscle, Smooth|Cysteine|verlukast|Quinolines|Membrane Proteins|montelukast | |
10852913 J. Biol. Chem. 2000 Male|Animals|Mice|Humans|*Testis|*Glycoprotein|*Kidney|Amino Acid Sequence|Membrane Glycoproteins|Northern Blots|Sequence Alignment|Exons|Membrane Transport Proteins|Chromosome Mapping|Introns|Cloning, Molecular|In Situ Hybridization|DNA, Complementary|Sequence Homology, Amino Acid|Cell Line|RNA, Messenger|Blotting, Western | |
10852956 Proc. Natl. Acad. Sci. U.S.A. 2000 PMC16572 Humans|Cricetinae|Animals|*Apolipoprotein B-48|CHO Cells|Endothelial Cells|Cricetulus|*Macrophage|lipoprotein triglyceride|Lipoproteins|*Atherosclerosis|Triglycerides|Monocytes|Foam Cells|Receptors, Lipoprotein|*Carrier Proteins|Lipids|mRNA|Transfections|Cloning, Molecular | |
10852960 Proc. Natl. Acad. Sci. U.S.A. 2000 PMC16515 Mice|Humans|Animals|*Lipofuscin|*Macular Degeneration|*Retina|Retinoids|Retinaldehyde|Rod Outer Segments|Retinal Pigment Epithelium|ATP-Binding Cassette Transporters|Pyridinium Compounds|Darkness | |
10854085 J Hum Hypertens 2000 Humans|Aged|*Angiotensin II|*Hypertension|candesartan|Tetrazoles|Antihypertensive Agents|candesartan cilexetil|Angiotensin II Receptor Blockers|diphenyl|Biphenyl Compounds|losartan carboxylic acid|Losartan|Benzimidazoles|Blood Pressure|Receptor, Angiotensin, Type 1|Angiotensin-Converting Enzyme Inhibitors|Irbesartan|Receptor, Angiotensin, Type 2|Hypertrophy, Left Ventricular | |
10854325 Nat. Cell Biol. 2000 *Receptor, Interleukin 1|TOLLIP protein, human|*Intracellular Signaling Peptides and Proteins|MyD88 Protein|Adaptor Proteins, Signal Transducing|Signal Transduction|Interleukin-1 Receptor-Associated Kinases|Interleukin 1|Protein Kinases|NF-kappa B|TNF Receptor-Associated Factor 6|Serine Threonine Kinase|Phosphorylation|Receptors, Immunologic|Antigens, Differentiation|IL-1RAcP | |
10856243 EMBO J. 2000 PMC203354 Mice|Animals|*Octamer Transcription Factor-6|*Schwann Cells|*Nerve, Peripheral|*Axons|Myelin Sheath|DNA-Binding Proteins|Transcription Factors|Early Growth Response Protein 2|Gene Expression Regulation, Developmental|Cell Differentiation|Peripheral Nervous System|*Regulatory Sequences, Nucleic Acid|*Organogenesis|Regeneration | |
10856244 EMBO J. 2000 PMC203359 RUNX1 protein, human|*Core Binding Factor Alpha 2 Subunit|CBFB protein, human|*Core Binding Factor beta Subunit|*Dimerization|*Leukemia, Myeloid, Acute|Proto-Oncogene Proteins|Nuclear Proteins|Transcription Factor AP-2|Protein Binding|Neoplasm Proteins|Protein Structure, Tertiary|Amino Acid Sequence | |
10856253 EMBO J. 2000 PMC203367 Humans|Rad30 protein|*DNA-Directed DNA Polymerase|*DNA Repair|*DNA Replication|DNA Damage|Thymine|Guanine|DNA|Templates, Genetic|Acetylaminofluorene|Nucleotides|Xeroderma Pigmentosum | |
10856300 J. Biol. Chem. 2000 Humans|*Endoplasmic Reticulum Stress|Transcription Factors|*Binding Site|DNA-Binding Proteins|*DNA|Endoplasmic Reticulum|Molecular Chaperones|Activating Transcription Factor 6|Heat-Shock Proteins|Genes, Reporter|HeLa Cells|Cell Nucleus|ATF6 protein, human | |
10856305 J. Biol. Chem. 2000 Humans|*Syntaxin 4|*Blood Platelets|*Thrombin|*Phosphorylation|Qc-SNARE Proteins|SNARE|Qb-SNARE Proteins|Exocytosis|Vesicular Transport Proteins|Carrier Proteins|Nerve Tissue Proteins|Cytoplasmic Granules|Protein Kinase C|Amino Acid Sequence|Protein Binding | |
10857746 Genomics 2000 Animals|Mice|Humans|ARNTL Transcription Factors|CLOCK Proteins|Period Circadian Proteins|Trans-Activators|Nuclear Proteins|Cell Cycle Proteins|Base Sequence|Circadian Rhythm|Promoter Regions, Genetic|NIH 3T3 Cells|RNA, Messenger | |
10858437 J. Biol. Chem. 2000 Mice|Animals|*Blood Platelets|*src-Family Kinases|*Thrombin|*Phosphorylation|convulxin|Endothelial Cells|*Lectins, C-Type|*Crotalid Venoms|Platelet Aggregation|Platelet Activation|*Collagen|Signal Transduction|Integrins|Phospholipase C gamma|Platelet Endothelial Cell Adhesion Molecule 1|Tyrosine | |
10858438 J. Biol. Chem. 2000 Humans|*Retinoid X Receptors|*Liver X Receptors|*Transcriptional Activation|*Promoter Regions, Genetic|Receptors, Retinoic Acid|Orphan Nuclear Receptors|9-cis-Retinoic Acid|Hydroxycholesterols|ATP Binding Cassette Transporter 1|Cholesterol|Tretinoin|ATP-Binding Cassette Transporters|*Sterols|mRNA|Foam Cell|Macrophages|Binding Site|Transfections | |
10858654 Trends Genet. 2000 Animals|*Wnt Signaling Pathway|Prospective Studies|CTNNB1 protein, human|beta Catenin|Wnt Proteins|Zebrafish Proteins|*Vertebrate|Proto-Oncogene Proteins|Frizzled Receptors|Dishevelled Proteins|Trans-Activators|Adaptor Proteins, Signal Transducing|Phosphoproteins|CaM KII|Protein Kinase C|Xenopus Proteins | |
10859164 Genes Dev. 2000 PMC316686 Humans|Mice|Animals|Protein Kinase|Phosphorylation|Cell Cycle Proteins|Checkpoint Kinase 1|Ataxia Telangiectasia Mutated Proteins|Tumor Suppressor Proteins|DNA Repair|DNA Damage|Mitosis|S Phase|Tumor Suppressor Protein p53|DNA-Binding Proteins|Hydroxyurea|Signal Transduction|*Cell Cycle Checkpoints|ATR protein, human | |
10860667 Genomics 2000 Humans|Animals|*Glucose Transport Facilitators|Base Sequence|Monosaccharide Transport Proteins|Amino Acid Sequence|cDNA|Cloning, Molecular|mRNA|Sequence Homology, Amino Acid|SLC2A9 protein, human | |
10860980 Proc. Natl. Acad. Sci. U.S.A. 2000 PMC16511 *Calcineurin|*Binding Site|DNA-Binding Proteins|Nuclear Proteins|NFATC Transcription Factors|Amino Acid Sequence|Cell Nucleus|Protein Binding|Phosphorylation|Gene Expression Regulation|Promoter Regions, Genetic|T Cells|*Protein Domains | |
10861009 Proc. Natl. Acad. Sci. U.S.A. 2000 PMC16564 *Thrombin|*Endothelial Cells|GRK5 protein, human|*G-Protein-Coupled Receptor Kinase 5|G-Protein-Coupled Receptor Kinases|*Signal Transduction|beta-Adrenergic Receptor Kinases|Phosphorylation|Cyclic AMP-Dependent Protein Kinases|Cell Line|Phosphatidylinositols | |
10861086 J. Immunol. 2000 *src-Family Kinases|Fc gamma receptor IIB|FCGR2B protein, human|*Receptors, IgG|*Phagocytosis|*Signal Transduction|Protein-Tyrosine Kinases|Proto-Oncogene Proteins c-hck|Phosphorylation|Syk Kinase|Macrophage|Actins|Intracellular Signaling Peptides and Proteins|Proto-Oncogene Proteins | |
10861246 Biochem. J. 2000 PMC1221155 Chlorocebus aethiops|Animals|Humans|Cattle|Neu3 protein, human|*Neuraminidase|*Plasma Membrane|COS Cells|Amino Acid Sequence|cDNA|Substrate Specificities|Transfections|Cloning, Molecular|Gangliosides|Sequence Homology, Amino Acid|Blotting, Northern|Hydrogen-Ion Concentration|Tissue Distributions|Amino Acids | |
10862053 Genes Chromosomes Cancer 2000 Humans|Animals|*Glycogen Synthase Kinase 3|*Axin Protein|CTNNB1 protein, human|beta Catenin|*Mutations|Trans-Activators|Wnt Proteins|Signal Transduction|Adenomatous Polyposis Coli Protein|Repressor Proteins|Protein Binding|Phosphorylation|Binding Sites|Calcium-Calmodulin-Dependent Protein Kinases|Cell Lines|Zebrafish Proteins|*Colon|FRAT1 protein, human | |
10862609 J. Biol. Chem. 2000 Rats|Animals|*Dehydroascorbic Acid|*Xenopus laevis|*Adipocytes|*Glucose Transporter Type 4|Insulin|ethylidene glucose|Glucose|2-Deoxyglucose|Biological Transport|Adipose Tissue|3-O-Methylglucose|Muscle Proteins|Cytochalasin B|Oocytes|Cell Membrane | |
10862613 J. Biol. Chem. 2000 Humans|*Topoisomerase II|*Isoenzymes|HeLa Cells|*SUMO-1 Protein|Teniposide|Topoisomerase II Inhibitors|TOP1 protein, human|Topoisomerase I|4,4'-(1,2-dimethyl-1,2-ethanediyl)bis-2,6-piperazinedione|Piperazines|Small Ubiquitin-Related Modifier Proteins|DNA-Binding Proteins|Cell Nucleus | |
10862738 Development 2000 Animals|*Hedgehog Proteins|Zinc Finger Protein GLI1|Drosophila Proteins|Signal Transduction|Oncogene Proteins|Transcription Factors|*Binding Sites|Drosophila|Gene Expression Regulation, Developmental|Trans-Activators|Wings, Animal|Drosophila melanogaster|DNA-Binding Proteins|Repressor Proteins|dpp protein, Drosophila | |
10862746 Development 2000 Animals|*Xenopus laevis|*Gastrulation|*Morphogenesis|Xenopus Proteins|Gastrula|Mesoderm|Wnt Proteins|Signal Transduction|Ectoderm|Dishevelled Proteins|Embryo, Nonmammalian|Phosphoproteins|Adaptor Proteins, Signal Transducing|Gene Expression Regulation, Developmental|Activin|Carrier Proteins | |
10862750 Development 2000 Animals|*Hedgehog Proteins|*Active Transport, Cell Nucleus|Signal Transduction|Drosophila Proteins|Drosophila|Wings, Animal|Transcription Factors|Drosophila melanogaster|Kinesin|Cyclic AMP-Dependent Protein Kinases|DNA-Binding Proteins|Repressor Proteins|Protein-Serine-Threonine Kinases|Cell Nucleus|*Limb Deformities, Congenital|Phosphorylation | |
10863037 Neurosci. Lett. 2000 Animals|Humans|Mice|*Serine|*Amino Acids, Neutral|Amino Acid Transport Systems|Carrier Proteins|Amino Acid Sequence|cDNA|Cloning, Molecular|Amino Acid Transport System ASC|Amino Acids|*Sodium|Biological Transport|mRNA|SLC3A2 protein, human|4F2 Heavy Chain|Xenopus laevis|Sequence Alignment|Oocytes|*Brain | |
10864948 J. Neurosci. 2000 PMC6772304 Animals|*Synaptic Vesicles|vesicular GABA transporter|Vesicular Inhibitory Amino Acid Transport Proteins|Vesicular Biogenic Amine Transport Proteins|Vesicular Acetylcholine Transport Proteins|Glutamate|Vesicular Transport Proteins|Neurotransmitter|GABA Plasma Membrane Transport Proteins|Membrane Glycoproteins|gamma-Aminobutyric Acid|Microscopy, Immunoelectron|Neurons|Biological Transport | |
10865125 Biochimie 2000 *Secretory Pathway|rab GTPases|rab3 GTP-Binding Proteins|Exocytosis|Membrane Fusion|GTP-Binding Proteins|Cytoplasmic Granules|Amino Acid Sequence|Nerve Tissue Proteins | |
10866047 Diabetes 2000 Humans|*Insulin|*Insulin-Secreting Cells|*Sulfonylurea Receptors|Potassium Channels, Inwardly Rectifying|*Insulin, Regular, Human|Islets of Langerhans|Insulin Secretion|Hypoglycemia|Hyperinsulinism|KATP Channels|*Cell Line|Adenosine Triphosphate|Glucose|Patch-Clamp Techniques | |
10866201 Nature 2000 Humans|Female|Pregnancy|Rats|Animals|*Pre-Eclampsia|*Neurokinin B|*Placenta|Syncytiotrophoblast|Hypertension, Pregnancy-Induced|Messenger RNA|Eclampsia|Case-Control Studies|Neurokinin A | |
10866302 Cancer Res. 2000 Humans|*Phosphoinositide Phosphatase|*Mutation, Missense|PTEN protein, human|*Phosphatase, PTEN|Genes, Tumor Suppressor|Mutations, Germline|Mutations|Inositol Phosphates | |
10866324 Cancer Res. 2000 Humans|Female|Mice|Animals|*Ataxia-Telangiectasia|*Phosphorylation|BRCA1 protein, human|*BRCA1 Protein|ATM protein, human|Ataxia Telangiectasia Mutated Proteins|Cell Cycle Proteins|DNA Repair|Tumor Suppressor Proteins|DNA Damage|Nuclear Protein|DNA-Binding Proteins|*Mutation|Serine | |
10866664 Mol. Cell. Biol. 2000 PMC85957 Humans|*RNA Polymerase II|*HIV-1|*Phosphorylation|*Serine|CDK9 protein, human|*Cyclin-Dependent Kinase 9|P-TEFb|cyclin-dependent kinase-activating kinase|Cyclin-Dependent Kinases|tat Gene Products, Human Immunodeficiency Virus|HIV Long Terminal Repeat|Cyclin T|Transcription, Genetic|Protein-Serine-Threonine Kinases|Transcription Factors|Cyclins | |
10866813 Eur. J. Biochem. 2000 Chlorocebus aethiops|Swine|Animals|Endothelial Cells|triphosphoric acid|CD39 antigen|Apyrase|ectoATPase|Adenosine Triphosphatases|Amino Acid Sequence|Antigens, CD|Base Sequence|Pyrophosphatases|*Nucleotides|COS-7 Cells|cDNA|Cloning, Molecular|Glycosylation|Sequence Homology, Amino Acid | |
10866835 Eur. J. Biochem. 2000 Mice|Animals|*Porcupines|Drosophila Proteins|Wnt1 Protein|Drosophila|Wnt Proteins|Amino Acid Sequence|Membrane Proteins|Proto-Oncogene Proteins|*Biological Evolution|Endoplasmic Reticulum|Sequence Alignment|Signal Transduction|porcupine protein, Drosophila | |
10867011 J. Biol. Chem. 2000 Mice|Animals|*CCAAT-Enhancer-Binding Protein-delta|STAT3 protein, human|*STAT3 Transcription Factor|NIH 3T3 Cells|*Cells, Epithelial|CCAAT Enhancer Binding Protein|Mammary Glands, Animal|Promoter Regions, Genetic|Gene Expression Regulation|STAT1 protein, human|STAT1 Transcription Factor|Trans-Activators|Activation, Transcriptional|Resting Phase, Cell Cycle|Cell Cycle|Transcription, Genetic | |
10867024 J. Biol. Chem. 2000 Humans|*Ligands|*Signal Transduction|BTC protein, human|Betacellulin|NRG3 protein, human|cimaglermin|Neuregulin-1|Epidermal Growth Factor|Receptor, ErbB-4|Phosphorylation|Receptor, ErbB-2|*Carrier Proteins|Dimerization|Cell Proliferation|Cell Line|ERBB4 protein, human | |
10868950 Diabetes 2000 Mice|Animals|Diabetes Mellitus, Type 2|Inward Rectifier K+ Channel|Islet Cells|Sulfonylurea Receptors|Insulin Secretion|Hyperinsulinism|Mice, Knockout|Glucose|Hyperglycemia|Insulin Resistance|Membrane Potential|Adenosine Triphosphate | |
10869344 J. Biol. Chem. 2000 *ral Guanine Nucleotide Exchange Factor|ras Proteins|Guanine Nucleotide Exchange Factors|Amino Acid Sequence|Signal Transduction|Protein Binding|Proto-Oncogene Proteins c-raf | |
10869557 FEBS Lett. 2000 Humans|*Transaldolase|Amino Acid Sequence|Binding Sites|Models, Molecular|Crystallography, X-Ray|Autoantigens|Sequence Alignment|Sequence Homology, Amino Acid|Aldolases|Autoantibodies|Active Site|Escherichia coli|Fructose-Bisphosphate Aldolase | |
10871282 J. Cell Biol. 2000 PMC2175135 GAB2 protein, human|GAB1 protein, human|GRB2 protein, human|*GRB2 Adaptor Protein|PTPN11 protein, human|*Protein Tyrosine Phosphatase, Non-Receptor Type 11|MET protein, human|*Proto-Oncogene Proteins c-met|Phosphoproteins|Binding Site|Phosphorylation|src Homology Domains|Protein Binding|Signal Transduction|Protein Structure, Tertiary|HGF protein, human|Hepatocyte Growth Factor|Amino Acid Sequence | |
10871633 J. Biol. Chem. 2000 *Transforming Growth Factor beta|SMAD3 protein, human|*Smad3 Protein|Trans-Activators|Signal Transduction|Transcription, Genetic|Gene Expression Regulation|Proto-Oncogene Proteins c-jun|Mitogen-Activated Protein Kinases|Protein-Serine-Threonine Kinases|Protein Binding|Transcriptional Activation|JNK Mitogen-Activated Protein Kinases|Genes, Reporter|Transfection|Phosphorylation | |
10872467 Annu. Rev. Biochem. 2000 Cyclic AMP Response Element-Binding Protein|Phosphorylation|*Gene Expression Regulation|Protein Kinase A|Transcription, Genetic|Signal Transduction|Protein Kinases|Protein Kinases, Calmodulin-Dependent|S6 Kinase|Cell Nucleus|Serine | |
10873388 Genomics 2000 Humans|Male|Mice|Animals|*Cloning, Molecular|cDNA|RTKN protein, human|Intracellular Signaling Peptides and Proteins|Amino Acid Sequence|Base Sequence|Exons|Chromosome Mapping|Sequence Alignment|Blotting, Northern|Introns|Sequence Homology, Amino Acid|Gene Expression|Open Reading Frame|RNA, Messenger|Signal Transduction|Tissue Distribution|rho GTP-Binding Proteins | |
10873595 Biochem. Biophys. Res. Commun. 2000 Humans|Animals|Rats|*Organic Anion Transporters|estrone sulfate|Estrone|Amino Acid Sequence|Sequence Alignment|Carrier Proteins|Tissue Distribution|Taurocholic Acid|Cloning, Molecular|RNA, Messenger|Membrane Transport Proteins|Oocytes | |
10873640 Biochem. Biophys. Res. Commun. 2000 Humans|*ATP-Binding Cassette Transporters|ABCA1 protein, human|ATP Binding Cassette Transporter 1|*Sterols|Cholesterol|cDNA|Macrophages|Monocytes|mRNA|Amino Acid Sequence|Lipoproteins, LDL|Introns|Exons|Cloning, Molecular|Biological Transport|Sequence Homology, Protein|Open Reading Frame|ABCA7 protein, human | |
10873660 Biochem. Biophys. Res. Commun. 2000 Humans|In Situ Hybridization, Fluorescence|*Promoter Regions, Genetic|*Chromosome Mapping|estrogen receptor alpha, human|ERalpha|Base Sequence|Binding Site|Estrogens|Receptors, Estrogen|Luciferase|Transcription Initiation Site|Cloning, Molecular|5' Flanking Region|Cell Surface Antigen | |
10875929 J. Biol. Chem. 2000 Humans|Mice|Animals|H19 long non-coding RNA|*mRNA|IGF2 protein, human|*Insulin-Like Growth Factor II|*RNA, Long Noncoding|RNA, Untranslated|Genomic Imprinting|Genes, Tumor Suppressor|*Protein Binding|Alleles|Exons | |
10875937 J. Biol. Chem. 2000 Humans|interleukin-22|interleukin-22 receptor|*Interferon|*Interferon Receptor|*Interleukin|Receptors, Interleukin|*Cytokines|IL10RB protein, human|*Interleukin-10 Receptor beta Subunit|IL10 protein, human|Interleukin-10|Cytokine Receptor|*Carrier Proteins|T Cells|*Antiviral Agents|Monocytes|Amino Acid Sequence|Ligands | |
10876237 Nat. Struct. Biol. 2000 Humans|*Homogentisate 1,2-Dioxygenase|Dioxygenases|Alkaptonuria|Oxygenases|Amino Acid Sequence|Active Site|Mutation|Crystallography, X-Ray|Mutations, Missense|Models, Molecular | |
10877843 J. Biol. Chem. 2000 Animals|Humans|Cricetinae|*Junctional Adhesion Molecule|*Tight Junctions|*Occludin|CHO Cells|Caco-2 Cells|Cricetulus|Zonula Occludens-1 Protein|Phosphoproteins|Cell Adhesion Molecules|Cell Adhesion|Epithelial Cells|Protein Binding | |
10878245 FEBS Lett. 2000 Animals|*Secretory Pathway|Calnexin|calreticulin, human|Calreticulin|Lectins|Glycoproteins|Molecular Chaperones|Endoplasmic Reticulum|Calcium-Binding Proteins|Golgi Apparatus|Protein Folding|lectin B, Phytolacca americana|*Pokeweed Mitogens|Amino Acid Sequence|Ribonucleoproteins|Protein Transport|Glycosylation | |
10878576 Bioessays 2000 Humans|Animals|*MAP Kinase Signaling System|MAPK, p38|Mitogen-Activated Protein Kinases|Signal Transduction|Substrate Specificity|Cell Differentiation | |
10878805 Nat. Cell Biol. 2000 Humans|Animals|ERBIN protein, human|*Adaptor Proteins, Signal Transducing|ERBB2 protein, human|*Receptor, ErbB-2|Carrier Proteins|Cytoskeletal Proteins|Protein Binding|Signal Transduction|Intracellular Signaling Peptides and Proteins|Cell Membrane|Binding Site|Disks Large Homolog 4 Protein|Amino Acid Sequence|*Transcription Factors|Cell Line|*Mammals | |
10878807 Nat. Cell Biol. 2000 VHL protein, human|Von Hippel-Lindau Tumor Suppressor Protein|DNA-Binding Proteins|Transcription Factors|Nuclear Proteins|*Ubiquitination|von Hippel-Lindau Disease|Ubiquitins|Ligases|Genes, Tumor Suppressor|Carcinoma, Renal Cell|Mutation|Kidney Neoplasms|Hypoxia | |
10878810 Nat. Cell Biol. 2000 WAS protein, human|*Wiskott-Aldrich Syndrome Protein|*Actins|*Polymerization|Wiskott-Aldrich Syndrome Protein, Neuronal|Actin-Related Protein 3|Actin-Related Protein 2|*Signal Transduction|Arp2-3 Complex|Wiskott-Aldrich Syndrome|Carrier Proteins|Nerve Tissue Proteins|Adaptor Proteins, Signal Transducing|src Homology Domains|cdc42 GTP-Binding Protein|Protein Binding | |
10879540 Nature 2000 Pregnancy|Female|Mice|Animals|*Alleles|Transcription Factors|*Homozygote|Receptor, Notch1|Membrane Proteins|Receptors, Cell Surface|Signal Transduction|Cell Differentiation|Cell Nucleus | |
10880360 Biochem. J. 2000 PMC1221184 Humans|*Phosphotyrosine|*Phosphorylation|*Tyrosine Kinase|*Phosphoinositides|*Phosphatidylinositol 3-Kinases|HEK293 Cells|SH2 Domain|src-Family Kinases|Adaptor Proteins, Signal Transducing|Blood Proteins|Signal Transduction|Binding Sites|Amino Acid Sequence|Tyrosine|Fatty Acids | |
10880574 Proc. Natl. Acad. Sci. U.S.A. 2000 PMC26981 Humans|anaritide|NPPA protein, human|*Atrial Natriuretic Factor|*Serine Protease|*Serine Endopeptidases|Myocytes, Cardiac|Protein Precursors|Transfection|Cell Line|Blotting, Western|Peptide Fragments|CORIN protein, human | |
10880960 Eur. J. Biochem. 2000 Humans|Male|Animals|Mice|*Basigin|*Immunoglobulin|Antigens, Neoplasm|Avian Proteins|Membrane Glycoproteins|Antigens, Surface|Blood Proteins|Antigens, CD|*Immunoglobulin Domain|Plasma Membrane|Amino Acid Sequence|Embryo Implantation|Glycosylation | |
10881997 J. Hum. Virol. 2000 Humans|*HIV-1|*Reverse Transcription|*Virions|Virus Replication|DNA, Viral|*Viral Structures|Transcription, Genetic|Cell Line | |
10882063 Mol. Cell 2000 *Disintegrins|ADAM17 protein, human|*TNF-alpha Converting Enzyme|gamma-Secretase|*Signal Transduction|ADAM Proteins|Membrane Proteins|*Proteolysis|Carrier Proteins|DNA Binding Protein|Drosophila Proteins|Amino Acid Sequence|Receptor, Notch1 | |
10882098 Mol. Cell 2000 Animals|*DNA Polymerase I|*Chromatin|*Eukaryotes|*DNA Replication|Replication Origin|Single-Stranded DNA-Binding Protein|DNA Helicases|Cell Cycle Proteins|S Phase|Cyclin-Dependent Kinases|Nuclear Proteins|*Eukaryotic Cells|Saccharomyces cerevisiae Proteins|Xenopus Proteins|Carrier Proteins|Cell Nucleus|Xenopus laevis|Cyclin-Dependent Kinase 2 | |
10882101 Mol. Cell 2000 Tifab protein, human|*TNF Receptor-Associated Factor 6|MAP kinase kinase kinase 7|*MAP Kinase Kinase Kinases|*Adaptor Proteins, Signal Transducing|*Signal Transduction Pathway|NF kB|Carrier Proteins|Intracellular Signaling Peptides and Proteins|Interleukin-1|Cytosol|Gene Expression Regulation | |
10882133 Mol. Cell 2000 PMC2811581 poly(A)-specific ribonuclease|*Exoribonucleases|RNA Caps|Cap Binding Protein|mRNA|mRNA Stability|EIF4E|Eukaryotic Initiation Factor-4G|Protein Biosynthesis|Saccharomyces cerevisiae | |
10882540 Front Neuroendocrinol 2000 Animals|Rats|Mice|VGF peptide|Neuropeptides|*Energy Metabolism|*Neurosecretory Systems|*Neurons|Arcuate Nucleus of Hypothalamus|Hypothalamus|Neurotrophic Factors|Pro-Opio-Melanocortin|Homeostasis|Mice, Knockout|Neuropeptide Y|mRNA|Brain|Gene Expression|Fasting|Pituitary Gland | |
10882729 J. Biol. Chem. 2000 Humans|TIGIRR-1 receptor|*Receptor, Interleukin 1|*Signal Transduction|IL1RAPL1 protein, human|Interleukin-1 Receptor Accessory Protein|NF-kappa B|Interleukin-1|Amino Acid Sequence|interleukin 18 protein, human|IL-18|Activation, Transcriptional | |
10882850 Mutat. Res. 2000 Humans|*DNA Glycosylase|HeLa Cells|NTH protein, E coli|Deoxyribonuclease (Pyrimidine Dimer)|Escherichia coli Proteins|Escherichia coli|Endodeoxyribonucleases|*DNA|DNA-(Apurinic or Apyrimidinic Site) Lyase|DNA Repair|Deoxyribonuclease IV (Phage T4-Induced)|4,6-diamino-5-N-formamidopyrimidine|Pyrimidines|Amino Acid Sequence|Substrate Specificity|*Protein Transport|*Cytoplasm|pyrimidine | |
10884298 J. Lipid Res. 2000 Humans|*Bile Salts|*Liver|Hepatocyte|bile acid-coenzyme A thioesterase|Thiolester Hydrolases|Acyltransferases|Peroxisomes|bile acid-CoA ligase|Coenzyme A Ligases|Taurine|Subcellular Fractions|Cytosol|Glycine | |
10884341 J. Mol. Biol. 2000 Humans|Animals|*DNA, Single-Stranded|*Electrons|MCM4 protein, human|*Minichromosome Maintenance Complex Component 4|DNA Helicase A|Minichromosome Maintenance Complex Component 6|DNA Replication|Cell Cycle Proteins|Minichromosome Maintenance Complex Component 7|MCM2 protein, human|Minichromosome Maintenance Complex Component 2|DNA-Binding Proteins|Nuclear Proteins|ATPase, DNA-Dependent|Gel Shift Analysis|Saccharomyces cerevisiae|Protein Binding|MCM4 protein, S cerevisiae | |
10884347 J. Mol. Biol. 2000 Humans|*Cyclin A|TP53 protein, human|*Tumor Suppressor Protein p53|CDK2 protein, human|Cyclin-Dependent Kinase 2|Cyclin|Cyclin-Dependent Kinases|CDC2-CDC28 Kinases|Phosphorylation|Cyclin-Dependent Kinase Inhibitor p21|Proliferating Cell Nuclear Antigen|Mutation|Amino Acid Sequence | |
10884394 J. Biol. Chem. 2000 Mice|Animals|*Ribonucleotide Reductase|*Sites, Allosteric|2'-deoxyadenosine triphosphate|Deoxyadenine Nucleotides|deoxyguanosine triphosphate|Deoxyguanine Nucleotides|Allosteric Regulation|thymidine 5'-triphosphate|Thymine Nucleotides|Substrate Specificity|Binding Sites|Adenosine Triphosphate|Kinetics|Active Site|Escherichia coli | |
10884405 Proc. Natl. Acad. Sci. U.S.A. 2000 PMC16613 Humans|*Proto-Oncogene Proteins c-kit|*Dimerization|Stem Cell Factor|Protein Binding|Protein Conformation|Models, Molecular|Amino Acid Sequence|Binding Site|Recombinant Proteins|Mast Cells|*Stem Cell | |
10887099 Blood 2000 Humans|Animals|Imerslund-Grasbeck syndrome|intrinsic factor-cobalamin receptor|*Intrinsic Factor|*Anemia, Megaloblastic|*Vitamin B 12 Deficiency|*Receptors, Cell Surface|*Proteinuria|*Malabsorption Syndromes|Vitamin B12|*Mutation|Protein Binding|Amino Acid Sequence|Cells, Epithelial|Vitamins|Finland | |
10887121 Blood 2000 Humans|Cricetinae|Animals|adhesion receptor|*Platelet Glycoprotein GPIb-IX Complex|*14-3-3 Proteins|*Phosphoinositide 3 Kinase|*Phosphatidylinositol 3-Kinases|von Willebrand Factor|Platelet Adhesiveness|Platelets|Protein Binding|Platelet Activation|Amino Acid Sequence|botrocetin|Crotalid Venoms|Phosphorylation|Binding Sites|Peptides|Thrombin|Signal Transduction | |
10887137 Blood 2000 FGFR1 protein, human|*Receptor, Fibroblast Growth Factor, Type 1|ZMYM2 protein, human|*DNA-Binding Proteins|*Transcription Factors|Zinc Fingers|Chromosomal Translocation|Trans-Activators|Phosphorylation|Carrier Proteins|Signal Transduction|Cell Transformation, Neoplastic|Amino Acid Sequence|Transfection|Proline | |
10887153 Genes Dev. 2000 PMC316741 Humans|POLK protein, human|*DNA-Directed DNA Polymerase|*DNA|Mutagenesis|DNA Polymerase beta|DNA Repair|DNA Damage|Pyrimidine Dimers|DNA Adducts|Templates, Genetic|Acetylaminofluorene|Mutagens|Base Sequence|Benzo(a)pyrene|DNA Primers|Escherichia coli | |
10887178 J. Biol. Chem. 2000 Humans|Animals|Chlorocebus aethiops|*Receptor Protein-Tyrosine Kinases|SPRY2 protein, human|Membrane Proteins|TYRP1 protein, human|*Membrane Glycoproteins|Intracellular Signaling Peptides and Proteins|Mitogen-Activated Protein Kinases|Epidermal Growth Factor|Epidermal Growth Factor Receptor Kinase|Drosophila Proteins|Signal Transduction|Nerve Tissue Proteins|ras Proteins|Amino Acid Sequence|Drosophila|Protein Binding|Proto-Oncogene Proteins c-cbl|Fibroblast Growth Factor | |
10887179 J. Biol. Chem. 2000 Animals|Cattle|*Mitochondrial Ribosomes|Ribosomes|Mitochondria|Intracellular Membranes|Protein Biosynthesis|*Mammals|Puromycin|RNA, Ribosomal|*Membrane|Proteins|Peptides | |
10889450 Free Radic. Biol. Med. 2000 dihydroorotate dehydrogenase|*Nitric Oxide|Oxidoreductases Acting on CH-CH Group Donors|*Oxidation-Reduction|*Mitochondria|Oxidoreductases|Chain, Respiratory|Cytochrome c Oxidase|4,5-dihydroorotic acid|Orotic Acid|coenzyme Q10|Ubiquinone|pyrimidine|Pyrimidines|Enzyme Inhibitors | |
10889531 Mol. Psychiatry 2000 Humans|*Attention Deficit Disorder with Hyperactivity|*Tourette Syndrome|SLC6A3 protein, human|*Dopamine Plasma Membrane Transport Proteins|*Alcoholism|Exons|Linkage Disequilibrium|Polymorphism, Genetic|Minisatellite Repeats|*Open Reading Frames|Membrane Glycoproteins|Introns|Genotype|Alleles|Nerve Tissue Proteins|Dopamine | |
10890900 Proc. Natl. Acad. Sci. U.S.A. 2000 PMC26955 *Golgi Complex|*Plasma Membrane|*Cholesterol|*Membrane Microdomains|Endoplasmic Reticulum|Brefeldin A|Biological Transport|Cyclodextrins|beta-Cyclodextrins|Cell Line|Viral Envelope Proteins|Nocodazole | |
10891391 Biochem. Biophys. Res. Commun. 2000 Animals|Humans|Female|Pregnancy|*Amino Acid Transport System A|*Amino Acid Transporter|Cloning, Molecular|Amino Acid Sequence|cDNA|Carrier Proteins|cDNA Library|Amino Acids|Biological Transport|Gene Expression|RNA, Messenger|Sequence Homology, Amino Acid|Cell Line|Sodium|Placenta | |
10891492 Mol. Cell. Biol. 2000 PMC86003 Rats|Chlorocebus aethiops|Animals|Mice|KSR-1 protein kinase|*Signal Transduction|Phosphorylation|Mitogen-Activated Protein Kinase Kinases|*Protein Isoforms|ras Proteins|Mitogen-Activated Protein Kinases|Proto-Oncogene Proteins c-raf|Enzyme Activation|Protein Binding|PC12 Cells|Epidermal Growth Factor|3T3 Cells|MAP Kinase Signaling System|COS Cells|Neurons|Nerve Growth Factors|*Brain | |
10891498 Mol. Cell. Biol. 2000 PMC86022 Humans|TP53 protein, human|*Tumor Suppressor Protein p53|*RNA Binding Protein|DNA-Binding Proteins|Cell Cycle|*Cell Cycle Arrest|HNRNPK protein, human|Heterogeneous-Nuclear Ribonucleoprotein K|Cell Cycle Proteins|Ribonucleoprotein, Heterogeneous Nuclear|Transcription Factors|Tumor Suppressor Proteins|G2 Phase|Genes, Tumor Suppressor|DNA Damage|Mitosis|Splicings, Alternative|mRNA | |
10891503 Mol. Cell. Biol. 2000 PMC86037 Humans|Mice|Animals|CASP8 protein, human|*Caspase 8|PLEC protein, human|*Plectin|Caspases|*Apoptosis|*Tumor Necrosis Factor Receptor|fas Receptor|Caspase 9|Caspase Inhibitors|Caspase 3|Poly ADP Ribose Polymerase|Enzyme Activation|PARP1 protein, human|Poly (ADP-Ribose) Polymerase-1|Lamin B | |
10892742 Cell 2000 Animals|*Axon Guidance|Drosophila|Drosophila Proteins|Axons|Receptors, Immunologic|Nerve Tissue Proteins|Signal Transduction|Tyrosine Kinase|Mutation|Phosphorylation | |
10893229 J. Biol. Chem. 2000 IRF7 protein, human|*Interferon Regulatory Factor-7|IRF3 protein, human|Interferon Regulatory Factor 3|Transactivator|Interferon Regulatory Factors|Activation, Transcriptional|Nuclear Proteins|Transcription, Genetic|Binding Sites|Promoter Regions, Genetic|Type I Interferon|Protein Binding|Interferon-alpha|Transfection|CCL5 protein, human|RANTES|Infections | |
10893425 J. Biol. Chem. 2000 Male|Humans|*Diacylglycerol Cholinephosphotransferase|phosphatidylethanolamine|Phosphatidylethanolamines|choline-ethanolaminephosphotransferase|Transferases (Other Substituted Phosphate Groups)|*Choline Kinase|Phosphotransferases|Phosphatidyl Choline|Ethanolaminephosphotransferase|Sequences, Amino Acid|CDP ethanolamine|Cytidine Diphosphate|diarachidonyl diglyceride|Diglycerides|*Genomics|Cloning, Molecular|Saccharomyces cerevisiae|cDNA | |
10894160 Immunity 2000 Humans|TNFRSF10A protein, human|TNFRSF10B protein, human|*Receptors, TNF-Related Apoptosis-Inducing Ligand|CASP8 protein, human|*Caspase 8|FADD protein, human|*MORT1 Protein|*Apoptosis|TNF-Related Apoptosis-Inducing Ligand|Caspases|fas Receptor|Caspase 9|Apoptosis Regulatory Proteins|Jurkat Cells|Signal Transduction|Tumor Necrosis Factor-alpha|Membrane Glycoproteins | |
10896159 Neuron 2000 Animals|Chlorocebus aethiops|CDK5 protein, human|*Cyclin-Dependent Kinase 5|*Phosphorylation|*Up-Regulation|cyclin-dependent kinase-activating kinase|*Neurite Outgrowth|*Genes, abl|Neurons|Neurites|Proto-Oncogene Proteins c-abl|Nerve Tissue Proteins|Carrier Proteins|Signal Transduction|Phosphoproteins|*Transcriptional Activation|COS Cells|Transfection|Tyrosine | |
10896663 J. Biol. Chem. 2000 Humans|*Farnesyl-Diphosphate Farnesyltransferase|farnesyl pyrophosphate|Polyisoprenyl Phosphates|Sites, Active|Amino Acid Sequence|Crystallography, X-Ray|Alkyl and Aryl Transferases|Binding Sites|Models, Molecular|Mutagenesis, Site-Directed|Catalysis|Dimerization|Sesquiterpenes|Aspartate|Kinetics|Sequence Homology, Amino Acid | |
10896934 J. Biol. Chem. 2000 *Phosphorylation|*beta3 Integrin|*Proto-Oncogene Proteins c-akt|*Threonine|Tyrosine Kinase|Platelet Glycoprotein GPIIb-IIIa Complex|Protein Binding|pp60 c-src|Signal Transduction|Platelet|Platelet Membrane Glycoproteins|src Homology Domains|Phosphotyrosine|Platelet Aggregation|Amino Acid Sequence|Cytoplasm|Tyrosine | |
10898789 Genes Dev. 2000 PMC316784 Animals|CTNNB1 protein, human|*beta Catenin|*Wnt Signaling Pathway|Transcription Factors|Wnt Proteins|Trans-Activators|Xenopus Proteins|Zebrafish Proteins|Homeodomain Proteins|Body Patterning|Transcription Factor 7-Like 1 Protein|HMGB Proteins|Proto-Oncogene Proteins|Xenopus laevis|Repressor Proteins|Lymphoid Enhancer-Binding Factor 1|Transcription Factor 7-Like 2 Protein|Gene Expression Regulation, Developmental | |
10898936 Arch. Biochem. Biophys. 2000 Pregnancy|Humans|Female|*Insulin-Like Growth Factor Binding Protein 4|IGF2 protein, human|*Insulin-Like Growth Factor II|*Pregnancy-Associated Plasma Protein-A|*Insulin-Like Growth Factor Binding Proteins|Insulin-Like Growth Factor I|Osteoblasts|Metalloendopeptidases|Cells, Cultured|Medium, Conditioned|Blotting, Western|Fibroblasts|Protein Binding | |
10899108 EMBO J. 2000 PMC313992 Humans|*Interleukin 12|*Cytokines|*Dimerization|Receptors, Cytokine|IL27RA protein, human|Receptors, Interleukin|Protein Conformation|Protein Binding|Amino Acid Sequence|Crystallography, X-Ray|Models, Molecular|Macromolecular Substances|Signal Transduction|Epitopes | |
10899166 J. Biol. Chem. 2000 Animals|Humans|Rats|Female|neuromedin U receptor|*Receptors, Neurotransmitter|neuromedin U|Neuropeptide|*Central Nervous System|Membrane Proteins|Amino Acid Sequence|Cloning, Molecular|Brain|Transfection|Binding Sites|RNA, Messenger|Calcium | |
10899599 Biochim. Biophys. Acta 2000 Humans|CTP synthetase|*DNA, Complementary|*Carbon-Nitrogen Ligases|Amino Acid Sequence|Ligases|Cloning, Molecular|Base Sequence|*Protein Isoforms|Escherichia coli|Open Reading Frame|Genetic Complementation Test|Sequence Homology, Amino Acid|Sequence Analysis, DNA | |
10899625 Biochim. Biophys. Acta 2000 Mice|Humans|Rats|Dogs|Animals|CMA1 protein, human|*Chymases|*Mast Cells|*Angiotensin II|cytotoxic T lymphocyte-specific serine protease|mast cell protease 4|Tryptases|Angiotensin I|Amino Acid Sequence|Substrate Specificity | |
10899937 J. Neurochem. 2000 Humans|CASP3 protein, human|*Caspase 3|*tau Proteins|*Apoptosis|Caspases|*Neurons|Alzheimer Disease|Peptide Fragments|Transfection | |
10899995 Proc. Natl. Acad. Sci. U.S.A. 2000 PMC26931 Humans|*Mitochondria|Cytosol|*Nucleotides|NT5E protein, human|5'-Nucleotidase|thymidine 5'-triphosphate|Thymine Nucleotides|Amino Acid Sequence|Substrate Specificity|cDNA|Green Fluorescent Proteins|GPI-Linked Proteins | |
10899997 Proc. Natl. Acad. Sci. U.S.A. 2000 PMC26939 stearidonic acid|*n-3 Polyunsaturated Fatty Acid|Mortierella|Fatty Acid Desaturases|gamma-Linolenic Acid|Polyunsaturated Fatty Acids|Acids, Fatty|Arachidonic Acid|Acetyltransferases|cDNA|Cloning, Molecular|Amino Acid Sequence|Saccharomyces cerevisiae|cDNA Library|Sequence Homology, Amino Acid | |
10900462 Mol. Carcinog. 2000 Humans|Animals|Mice|*Furin|KEX2 protein, S cerevisiae|*Proprotein Convertases|PCSK7 protein, human|Subtilisins|Serine Endopeptidases|Saccharomyces cerevisiae Proteins|Saccharomyces cerevisiae|Protein Processing, Post-Translational|*Neoplastic Processes|Protein Precursors|Gene Expression|Amino Acid Sequence|Transfections|Tumor|Amino Acid Motifs | |
10902565 IUBMB Life 2000 *Pseudouridine|Nucleic Acid Conformation|pseudouridine synthases|Intramolecular Transferases|23S rRNA|Base Sequence|tRNA|snoRNA|Hydro-Lyases|Ribosomes|Escherichia coli|mRNA | |
10903140 Biochem. J. 2000 PMC1221206 Animals|Male|*Glutamine|*Arginine|Endothelial Cells|*Amino Acid Transporter|SLC7A6 protein, human|*Amino Acid Transport Systems, Basic|SLC3A2 protein, human|*Fusion Regulatory Protein 1, Heavy Chain|*Biological Transport|Amino Acids|Carrier Proteins|Fusion Regulatory Protein-1|Leucine|*Dimerization|Xenopus laevis|Amino Acids, Neutral|Membrane Glycoprotein|Lysine | |
10903185 Development 2000 Animals|*Drosophila|Drosophila Proteins|Photoreceptor Cells, Invertebrate|Signal Transduction|Receptors, Notch|*Cell Differentiation|Frizzled Receptors|Cell Polarity|Receptors, G-Protein-Coupled|Transcription Factors|Cell Lineage|Membrane Proteins|Intracellular Signaling Peptides and Proteins|Dishevelled Proteins|Adaptor Proteins, Signal Transducing|Phosphoproteins|Eye | |
10903204 Science 2000 Golgi Apparatus|Endoplasmic Reticulum|Vesicular Transport Proteins|Soluble N-ethylmaleimide-Sensitive-Factor Attachment Protein Receptor|Carrier Proteins|Saccharomyces cerevisiae Proteins|rab1 GTP-Binding Proteins|Golgi Matrix Proteins|Biological Transport|Membrane Glycoproteins|SDHD protein, human|*Succinate Dehydrogenase | |
10903344 J. Clin. Invest. 2000 PMC314311 Humans|Chlorocebus aethiops|Animals|Sucrase-isomaltase deficiency, congenital|*Sucrase-Isomaltase Complex|*Carbohydrate Metabolism, Inborn Errors|Golgi Apparatus|Endoplasmic Reticulum|Sucrase|Protein Transport|Protein Folding|Point Mutation|Amino Acid Sequence|COS Cells|Mutation|Isomaltase|Intestines|Cell Membrane|Biological Transport|Phenotype|Transfections | |
10904264 Trends Genet. 2000 *SIN3 Histone Deacetylase Complex|Histone Deacetylase Complexes|Mi-2 Nucleosome Remodeling and Deacetylase Complex|DNA-Binding Proteins|Transcription Factors|Repressor Proteins|Transcription, Genetic|Amino Acid Sequence | |
10906340 J. Biol. Chem. 2000 *Nitric Oxide|potassium superoxide|*Superoxides|*Peroxynitrous Acid|*Nitrates|*Nitrogen Oxides|3-nitrotyrosine|*Tyrosine|Xanthine Oxidase|Kinetics|Hydrogen-Ion Concentration|Carbon Dioxide|spermine nitric oxide complex|Spermine | |
10908322 Nucleic Acids Res. 2000 PMC102664 Humans|*Substrate Specificity|Gas Chromatography-Mass Spectrometry|oxoguanine glycosylase 1, human|*DNA Glycosylases|DNA-Formamidopyrimidine Glycosylase|DNA Repair|DNA Damage|8-hydroxyguanine|Guanine|DNA|*Mutations|Escherichia coli Proteins|Escherichia coli|2,6-diamino-4-hydroxy-5-formamidopyrimidine|Pyrimidines|Gamma Rays|Kinetics|*Tumors | |
10908605 J. Neurosci. 2000 PMC6772538 Rats|Animals|NGF protein, human|*Nerve Growth Factor|*Cell Differentiation|Receptor, trkA|Signal Transduction|PC12 Cells|Receptors, Nerve Growth Factor|Phosphorylation|*Receptors, Antigen, B-Cell|Phosphotyrosine|Neurons|Phosphatidylinositol 3-Kinases|Proto-Oncogene Proteins|Endocytosis|Cell Survival|Type C Phospholipases | |
10908652 Proc. Natl. Acad. Sci. U.S.A. 2000 PMC16810 *Nucleoprotein|*DNA|DNA-Binding Proteins|Nuclear Proteins|Amino Acid Sequence|DNA Sequence|Virus Integration|Protein Binding|Sequence Homology, Amino Acid|Mitosis | |
10910910 Blood 2000 Humans|Cricetinae|Animals|F8 protein, human|*Factor VIII|*von Willebrand Factor|*Hemophilia A|CHO Cells|Cricetulus|von Willebrand Diseases|*Mutations|Protein Binding|*Hemostatics|Binding Sites|Point Mutation|*Protein Domains | |
10911365 J. Cell. Physiol. 2000 Humans|Mice|Rats|Animals|RUNX2 protein, human|*Core Binding Factor Alpha 1 Subunit|Transcription Factor|Promoter Regions, Genetic|Gene Expression Regulation|Binding Sites|Protein Isoforms|Reporter Gene|Osteoblasts|Activation, Transcriptional|Neoplasm Proteins|*Bone|Cell Differentiation|Base Sequence|Conserved Sequence|Osteocalcin|Protein Binding|Cell Line | |
10911995 Mol. Cell 2000 Animals|*Nuclear Envelope|*Hydrolysis|*ran GTP-Binding Protein|Guanosine Diphosphate|Nuclear Proteins|Cell Cycle Proteins|Guanine Nucleotide Exchange Factors|Guanosine Triphosphate|Cell Nucleus|Chromatin|Xenopus Proteins|Xenopus laevis|DNA-Binding Proteins|GTP gamma S | |
10912521 Pediatr. Nephrol. 2000 Mice|Animals|*Insulin-Like Growth Factor Binding Protein 2|IGF1 protein, human|IGF-1|Insulin-Like Growth Factor Binding Proteins|Growth Hormone|Insulin|Fasting|Blotting, Western|Mice, Transgenic|Kidney | |
10913131 J. Biol. Chem. 2000 *src Homology Domains|GRB2 protein, human|*GRB2 Adaptor Protein|GAB2 protein, human|SLP-76 signal Transducing adaptor proteins|GAB1 protein, human|Phosphoproteins|*Protein Binding|MET protein, human|Hepatocyte Growth Factor Receptor|Binding Site|Phosphorylation|EGFR protein, human|Receptors, Epidermal Growth Factor|Signal Transduction|Amino Acid Sequence|Blotting, Western|Carrier Proteins | |
10913147 J. Biol. Chem. 2000 *Insulin|*Forkhead Proteins|*Phosphoenolpyruvate|*Phosphoenolpyruvate Carboxykinase (ATP)|IGFBP1 protein, human|Insulin-Like Growth Factor Binding Protein 1|*Insulin, Regular, Human|Response Elements|Promoter Regions, Genetic|Nuclear Proteins|*Phosphoenolpyruvate Carboxylase|Proto-Oncogene Proteins c-akt|Mutations|Somatomedins | |
10913176 Mol. Cell. Biol. 2000 PMC86070 Humans|*RNA Polymerase I|TP53 protein, human|*Tumor Suppressor Protein p53|Pol1 Transcription Initiation Complex Proteins|Transcription, Genetic|SET protein, human|Transcription Factors|rDNA|RNA Polymerase II|Histone Chaperones|rRNA Promoter|TATA-Binding Protein|RNA, Ribosomal|Protein Binding | |
10913181 Mol. Cell. Biol. 2000 PMC86075 Mice|Animals|*Cell Cycle|Transcription Factor DP1|Cell Cycle Proteins|Retinoblastoma-Binding Protein 1|E2F Transcription Factors|Nuclear Proteins|E2F1 Transcription Factor|S Phase|Cell Division|Promoter Regions, Genetic|CCAAT-Enhancer-Binding Proteins|Transcription, Genetic|Gene Expression Regulation|Binding Sites|Protein Binding | |
10913193 Mol. Cell. Biol. 2000 PMC86087 Humans|Animals|Mice|*Cell Nucleus|*Phosphorylation|PTK6 protein, human|Tyrosine Kinase|RNA Binding Protein|src-Family Kinases|Neoplasm Proteins|Cytoplasm|Adaptor Proteins, Signal Transducing|DNA-Binding Proteins|Mitosis|RNA|SH2 Domains|*Cell Cycle Proteins|HeLa Cells|Cell Cycle | |
10913253 Biochemistry 2000 Humans|*Myotonin-Protein Kinase|*Dystrophy, Myotonic|AKT1 protein, human|*Protein Kinase B|ROCK1 protein, human|rho-Kinase|Amino Acid Sequence|Recombinant Proteins|Muscle|Electrophoresis, Polyacrylamide Gel | |
10913441 J. Biol. Chem. 2000 Humans|*Kinesin|*Organelle|KTN1 protein, human|*Membrane Proteins|Microtubules|*Protein Binding|*Cell Movement|Dyneins|Amino Acid Sequence|Cell Line | |
10914484 J. Leukoc. Biol. 2000 Humans|Mice|Animals|*Neutrophils|*Chemotactic Factors|*Chemotaxis|Dendritic Cells|CD8-Positive T-Lymphocytes|Monocytes|Antigen Presentation|Lymphocyte Activation|CD4-Positive T-Lymphocytes|Tumor Necrosis Factor-alpha|Granulocyte-Macrophage Colony-Stimulating Factor|Leukocyte Common Antigens|Cell Differentiation|Defensins | |
10914684 Hum. Genet. 2000 Humans|*Congenital Disorders of Glycosylation|*Glycosylation|Mutation|Exons|Saccharomyces cerevisiae|Glucosyltransferases|Allele|Membrane Proteins|Sequence Analysis | |
10915768 Hum. Mol. Genet. 2000 Humans|*Ataxin-3|*Saccharomyces cerevisiae|Machado-Joseph Disease|Ubiquitin|Nuclear Proteins|Nerve Tissue Proteins|DNA-Binding Proteins|Repressor Proteins|polyglutamine|Peptides|Proteasome Endopeptidase Complex|*Yeast, Dried|Nucleotide Excision Repair|Protein Binding|Intranuclear Inclusions|RAD23 protein, S cerevisiae|Saccharomyces cerevisiae Proteins | |
10915796 J. Biol. Chem. 2000 Animals|Humans|*DNA, Complementary|mannosyl-oligosaccharide 1,2-alpha-mannosidase|*Mannosidases|*Golgi Apparatus|Endoplasmic Reticulum|Mannose|Oligosaccharides|Amino Acid Sequence|Substrate Specificity|1 Deoxymannojirimycin|Catalytic Domain|*Protein Biosynthesis|Hydrolysis | |
10916156 Trends Biochem. Sci. 2000 *RNA Polymerase II|transcription factor TFIIE|Transcription, Genetic|Transcription Factors|Transcription Factor TFIIH|Chromatin|Protein Binding|Phosphorylation|Eukaryotic Cells | |
10917520 Nature 2000 Humans|*Fc epsilon RI|*Immunoglobulin E|*Immunoglobulin Fc Fragments|Protein Binding|Binding Sites|Models, Molecular|*Biophysical Phenomena | |
10917896 J. Nutr. 2000 glutamyl carboxylase|*Carbon-Carbon Ligases|Vitamin K|Substrate Specificity|Amino Acid Sequence|Recombinant Proteins|Kinetics|Binding Site|Glutamic Acid|Cell Line | |
10918587 Oncogene 2000 Humans|Mice|Rats|Animals|NIH 3T3 Cells|FGFR1 protein, human|*Receptor, Fibroblast Growth Factor, Type 1|FGFR3 protein, human|*Receptor, Fibroblast Growth Factor, Type 3|FGFR4 protein, human|*Receptor, Fibroblast Growth Factor, Type 4|Signal Transduction|Phosphorylation|Thanatophoric dysplasia, type 2|Thanatophoric Dysplasia|STAT1 protein, human|STAT1 Transcription Factor|Phospholipase C gamma|STAT3 protein, human|STAT3 Transcription Factor|Mitogen-Activated Protein Kinases|PTPN11 protein, human | |
10918611 Oncogene 2000 Humans|*beta-Transducin Repeat-Containing Proteins|*Phosphorylation|NFKBIA protein, human|I Kappa B-alpha Protein|I-kappa B Proteins|CHUK protein, human|IkappaB Kinase|Ubiquitins|Cullin Proteins|SKP Cullin F-Box Protein Ligases|Cell Cycle Proteins|DNA-Binding Proteins|NF-kappa B|*Signal Transduction|Ubiquitin-Protein Ligases|RBX1 protein, human|Carrier Proteins|Anaphase-Promoting Complex-Cyclosome | |
10919662 Cancer Res. 2000 Humans|*Alternative Splicing|TCF7L2 protein, human|*Transcription Factor 7-Like 2 Protein|C-terminal binding protein|DNA-Binding Proteins|*Colorectal Cancers|CTNNB1 protein, human|beta Catenin|*DNA Mutational Analysis|Transcription Factors|Isoforms|Exons|Base Sequence|Transcription, Genetic|*Cell Lines|Trans-Activators|Signal Transduction|Amino Acid Sequence | |
10919671 Cancer Res. 2000 Humans|glutathione peroxidase GPX1|*Glutathione Peroxidase|superoxide dismutase 2|*Manganese Superoxide Dismutase|*Redox|*Cell Cycle|Reactive Oxygen Species|Hydrogen Peroxide|Cell Division|Tumor Cells, Cultured|Superoxide Radical|Antioxidants|Transfections|Glutathione|Glioma|*Cell Proliferation | |
10919676 Cancer Res. 2000 STAT5A protein, human|*STAT5 Transcription Factor|IL9 protein, human|*Interleukin-9|JAK1 protein, human|Janus Kinase 1|Signal Transduction|*Tumor Suppressor Proteins|DNA-Binding Proteins|Trans-Activators|Janus Kinase 2|Phosphorylation|Receptor, Interleukin-9|STAT3 protein, human|STAT3 Transcription Factor|Enzyme Activation|JAK3 protein, human|Janus Kinase 3 | |
10920397 Trends Microbiol. 2000 *Active Transport, Cell Nucleus|*mRNA|*Influenza, Human|Influenza A virus|Pre-mRNA|RNA-Binding Proteins|RNA, Viral|Viral Nonstructural Proteins|Poly A|Virus Replication|Cell Nucleus|Nuclear Proteins | |
10921872 EMBO J. 2000 PMC306613 Animals|*Lactate Transporter|Symporters|*Plasma Membrane|Basigin|Membrane Glycoprotein|Muscle Proteins|Antigens, Neoplasm|Glycoprotein|Antigens, Surface|Avian Proteins|Antigens, CD|Transfection|Lactate|Cell Lines | |
10921873 EMBO J. 2000 PMC306616 *COPI|*COP-Coated Vesicles|epsilon-COP|Golgi Apparatus|Endoplasmic Reticulum|Saccharomyces cerevisiae|(T,G)-A-L|Peptides|Amino Acid Sequence|Protein Binding|Cytosol|Membrane Proteins|*Ubiquitin-Protein Ligases|Protein Transport|*Glatiramer Acetate|COP1 protein, human | |
10921897 EMBO J. 2000 PMC306603 Humans|RAD52 protein, human|*Rad52 DNA Repair and Recombination Protein|*DNA, Single-Stranded|Replication Protein A|Rad51 Recombinase|DNA Repair|DNA-Binding Proteins|Saccharomyces cerevisiae Proteins|Recombination, Genetic|DNA|Protein Binding|Complementary DNA | |
10921906 Genes Dev. 2000 PMC316813 Mice|Animals|*C EBPalpha|*C EBPbeta|CCAAT Enhancer Binding Protein|*Isoforms|Nuclear Proteins|Cell Differentiation|3T3-L1 Cells|Gene Expression Regulation|mRNA|EIF-2alpha|Open Reading Frame|Signal Transduction | |
10921920 J. Biol. Chem. 2000 Animals|CTNNB1 protein, human|*beta Catenin|*Protein A|CHD8 protein, human|Transcription Factors|*Protein Binding|TCF Transcription Factors|Xenopus laevis|Trans-Activators|DNA-Binding Proteins|Xenopus Proteins|Wnt Proteins|Axin Protein|Signal Transduction|Repressor Proteins|Body Patterning|Calcium-Calmodulin-Dependent Protein Kinases|Phosphorylation | |
10922044 Proc. Natl. Acad. Sci. U.S.A. 2000 PMC34021 Mice|Animals|*Oxygen|*Nitrogen|Mycobacterium tuberculosis|Tuberculosis|NOS2 protein, human|Inducible Nitric Oxide Synthase|Reactive Nitrogen Species|Nitric Oxide Synthase|Reactive Oxygen Species|Nitric Oxide|Phagocyte|Oxidase|Mice, Knockout | |
10922363 J. Biol. Chem. 2000 Rats|Animals|*Prostaglandin-E Synthases|PTGS1 protein, human|*Cyclooxygenase 1|*Dinoprostone|Cyclooxygenase 2|Microsomes|Intramolecular Oxidoreductases|Cytosol|Isoenzymes|Fibroblasts|Cells, Cultured|Membrane Proteins|Lipopolysaccharides|RNA, Messenger | |
10922383 J. Med. Genet. 2000 PMC1734666 Humans|*Congenital Disorders of Glycosylation|Escherichia coli|Phosphotransferases (Phosphomutases)|Mutations|Exon|Mutations, Missense|Glycosylation | |
10922406 J. Natl. Cancer Inst. 2000 *Histone Deacetylase Inhibitors|trichostatin A|Hydroxamic Acid|Suberoylanilide Hydroxamic Acid|Histone Deacetylase|*Apoptosis|Histones|Acetylation|Chromatin|*Cell Differentiation|Gene Expression Regulation, Neoplastic|Tumor Cells, Cultured|Cell Cycle|Protein Processing, Post-Translational | |
10922475 FEBS Lett. 2000 Humans|N,N'-bis(4-azidobenzoyl)cystine|Amino Acid Sequence|*Mitochondria|Sequence Alignment|Cloning, Molecular|ATP-Binding Cassette Transporters|cDNA|Chromosome Mapping|Sequence Homology, Amino Acid|Genome|Chromosome|RNA, Messenger|Pseudogene|Adenosine Triphosphate | |
10924277 Mol. Genet. Metab. 2000 Humans|*Glycosylation|*Mutations|Congenital Disorders of Glycosylation|Allele|Saccharomyces cerevisiae|Genetic Complementation Test|Glucosyltransferases|Membrane Proteins|Amino Acid Sequence|Oligosaccharides | |
10924361 Biochem. Biophys. Res. Commun. 2000 *Myosin-Light-Chain Phosphatase|protein kinase N|*Phosphorylation|cyclopropapyrroloindole|*Protein Kinase C|Indoles|ROCK1 protein, human|rho-Kinase|Phosphoproteins|Muscle Proteins|Phosphoprotein Phosphatases|Muscle, Smooth, Vascular|Vasoconstriction|Muscle Contraction|Calcium | |
10924499 J. Biol. Chem. 2000 Cricetinae|Male|Animals|Humans|*Captopril|CHO Cells|Cricetulus|ACE protein, human|*Angiotensin Converting Enzyme|*Carboxypeptidases|Angiotensin-Converting Enzyme Inhibitors|Angiotensin I|Lysinopril|Enalaprilat|Amino Acid Sequence|*Endopeptidases|Binding Sites|Hydrolysis|Sequence Homology, Amino Acid|Blotting, Northern|Kinetics|Cloning, Molecular | |
10925149 Brain Res. Mol. Brain Res. 2000 Animals|Humans|Mice|Down Syndrome Critical Region|*Down Syndrome|Cell Adhesion Molecules|Membrane Proteins|Cell Adhesion|Blotting, Western|Transfections|cDNA|Interactions, Cell|Brain|Cations, Divalent|Nervous System|Cell Membrane|Dscam protein, mouse | |
10925294 J. Immunol. 2000 Animals|MBL2 protein, human|*Mannose-Binding Lectin|*Mannose-Binding Protein-Associated Serine Proteases|Collectins|Complement Activation|Complement C1s|Serine Endopeptidases|Lectins|Carrier Proteins|Vertebrate | |
10926775 Dev. Biol. 2000 Humans|Male|Mice|Animals|*Meiosis|CCNA1 protein, human|*Cyclin A1|HeLa Cells|*M Phase-Promoting Factor|CDC25A protein, human|cdc25 Phosphatases|Type B Cyclin|Mitosis|Metaphase|CDC2 Protein Kinase|Spermatocytes|G2 Phase|Phosphorylation|Oocytes|Prophase|Type A Cyclin|Okadaic Acid | |
10926824 Biochem. J. 2000 PMC1221222 Humans|*Acidosis, Renal Tubular|Papua New Guinea|Malaysia|*Elliptocytosis, Hereditary|Anion Exchange Protein 1, Erythrocyte|*Erythrocytes|*Mutations|*Hematologic Diseases|Erythrocytes, Abnormal|*Asian Continental Ancestry Group|Mutant Proteins|Kidney | |
10926844 Biochem. J. 2000 PMC1221242 Humans|HDAC8 protein, human|*Histone Deacetylase|*Repressor Proteins|trichostatin A|Hydroxamic Acids|Histone Deacetylase Inhibitors|Amino Acid Sequence|Acetylation|Nucleotide Sequence|Histones|Sequence Alignment|Sequence Homology, Amino Acid|Active Site|Models, Molecular|Crystallography, X-Ray|Cloning, Molecular|London | |
10928988 FASEB J. 2000 Humans|Male|Mice|Animals|*Meiosis|MSH4 protein, human|*Cell Cycle Proteins|MutL Homolog 1|Spermatocytes|MutL Proteins|Synaptonemal Complex|Nuclear Proteins|DNA-Binding Proteins|Adenosine Triphosphatases|Carrier Proteins|*Mammals|Recombination, Genetic|Adaptor Proteins, Signal Transducing|Neoplasm Proteins|MLH1 protein, human | |
10929008 Glycobiology 2000 Humans|4-nitrophenyl-alpha-glucosidase|*Solubility|*alpha-Glucosidases|Amino Acid Sequence|Substrate Specificities|*Dimerization|Glucose|cDNA|Glycoproteins|Oligosaccharides|Binding Site|Endoplasmic Reticulum|Catalysis|Kinetics|Cell Line | |
10929711 Cell 2000 Humans|*Protein, Mitochondrial|*Cytochromes c|*Carrier Proteins|CASP9 protein, human|Caspase 9|APAF1 protein, human|Apoptotic Protease-Activating Factor 1|Caspases|Apoptosis|*Cell Death|Mitochondria|X-Linked Inhibitor of Apoptosis Protein|Intracellular Signaling Peptides and Proteins|Cytosol|Caspase Inhibitors|*Protein Processing, Post-Translational|Caspase 3|Enzyme Activation | |
10930409 J. Biol. Chem. 2000 Humans|*DNA Glycosylase|*Kinetics|*DNA Repair|Endodeoxyribonucleases|Deoxyribonuclease (Pyrimidine Dimer)|Thymine|Base Pair Mismatch|Substrate Specificity|5 Methylcytosine|Uracil|MED1 protein, human|*Mediator Complex Subunit 1|Binding Sites|Amino Acid Sequence|Guanine|DNA|MBD4 protein, human | |
10930463 Mol. Biol. Cell 2000 PMC14949 *Transforming Growth Factor beta|*Cysteine|LTBP2 protein, human|Latent TGF-beta Binding Proteins|*Protein Binding|Fibrillins|Amino Acid Sequence|Carrier Proteins|Intracellular Signaling Peptides and Proteins|Isoforms|Adaptor Proteins, Signal Transducing|Extracellular Matrix|TGFB1 protein, human|Transforming Growth Factor beta1|Binding Sites|Fibrillin-1|Peptides|*Protein Transport | |
10930503 Biochim. Biophys. Acta 2000 Animals|Humans|Rats|*Amino Acid Transport System A|Amino Acids|Amino Acid Transport Systems|mRNA|Carrier Proteins|Amino Acid Sequence|Biological Transport|beta-Alanine|Amino Acids, Neutral|Cloning, Molecular|*Ion Transport|Liver|Sequence Homology, Amino Acid|Hepatoma|Substrate Specificity|Liver Neoplasms | |
10931839 J. Biol. Chem. 2000 *Phosphorylation|*Phosphotyrosine|*Tyrosine|Fc epsilon RI|Protein Tyrosine Kinase|Signal Transduction|Syk Kinase|Intracellular Signaling Peptides and Proteins|Mast Cells|Cell Degranulation|Protein Binding|Cell Membrane|Enzyme Precursors | |
10932256 Nat. Struct. Biol. 2000 Humans|rimabotulinumtoxinB|Botulinum Toxins, Type A|*Binding Sites|Clostridium botulinum|incobotulinumtoxinA|Neurotoxins|Protein Binding|Receptors, Cell Surface|*Catalysis|Amino Acid Sequence|Crystallography, X-Ray|Models, Molecular|Active Site|Gangliosides | |
10933394 Immunity 2000 *Antigens, CD19|lyn protein-tyrosine kinase|*src-Family Kinases|*B-Lymphocytes|Receptors, Antigen, B-Cell|Phosphorylation|Signal Transduction|Phosphatidylinositol 3-Kinases|Antigens, CD|*Adaptor Proteins, Signal Transducing | |
10934188 J. Biol. Chem. 2000 Animals|*Drosophila|*Death Domain|*Caspases|FADD protein, human|Fas-Associated Death Domain Protein|Apoptosis|fas Receptor|APAF1 protein, human|Apoptotic Protease-Activating Factor 1|Caspase 8|Cell Death|Protein Binding|Signal Transduction|Amino Acid Sequence | |
10934197 J. Biol. Chem. 2000 Humans|*Neurocan|*Binding Site|Neural Cell Adhesion Molecules|Chondroitin Sulfate Proteoglycans|Membrane Glycoprotein|Protein Binding|Neurons|Nerve Tissue Proteins|Lectins, C-Type|Leukocyte L1 Antigen Complex|*Biophysical Phenomena | |
10934204 J. Biol. Chem. 2000 Animals|Chlorocebus aethiops|*Guanine Nucleotide Exchange Factors|RAP1A protein, human|rap1 GTP-Binding Proteins|ras GEFs|Generalized Epilepsy with Febrile Seizures Plus|*Seizures, Febrile|ras Proteins|*Epilepsy, Generalized|COS Cells|Protein Binding|Transfection|Enzyme Activation|Mitogen-Activated Protein Kinases|Guanosine Triphosphate | |
10934207 J. Biol. Chem. 2000 Humans|lysyl hydroxylase 3, human|*Procollagen-Lysine, 2-Oxoglutarate 5-Dioxygenase|UDP glucose-collagen glucosyltransferase|Glucosyltransferases|Amino Acid Sequence|Cell Line|Isoforms|Fibroblasts|Skin|Post-Translational Modifications|Amino Acids|cDNA|Active Site | |
10934230 J. Exp. Med. 2000 PMC2193217 Cricetinae|Animals|*Leukotriene B4|CHO Cells|Cricetulus|Receptors, Leukotriene B4|*Inflammation|Chemotaxis|Signal Transduction|Gene Expression Regulation|Leukocytes|*Immune System Diseases|Cloning, Molecular|Neutrophils|Granulocytes|Cyclase, Adenylyl | |
10934324 J. Neurobiol. 2000 *Semaphorin|*Axon Guidance|Growth Cones|Collapsin-1|plexin|Nerve Tissue Proteins|Axons|Neuropilin-1|Dorsal Root Ganglion|Neurons|Cell Adhesion Molecules|Receptors, Cell Surface|Signal Transduction | |
10934472 Nat. Cell Biol. 2000 Cricetinae|Animals|JAG1 protein, human|*Jagged-1 Protein|NOTCH2 protein, human|*Receptor, Notch2|*Signal Transduction|Serrate-Jagged Proteins|Membrane Proteins|Intercellular Signaling Peptides and Proteins|Ligands|Calcium-Binding Proteins|Notch Receptors|Receptor, Notch1|Intracellular Signaling Peptides and Proteins|Transcription Factors|Protein Binding|CHO Cells | |
10935490 Neoplasia 2000 PMC1508104 FGFR1 protein, human|*Receptor, Fibroblast Growth Factor, Type 1|*Phosphorylation|ZMYM2 protein, human|Signal Transduction|STAT5A protein, human|STAT5 Transcription Factor|Myeloproliferative Disorders|Oncogene Proteins, Fusion|Translocation, Genetic|*B Cells|Carrier Proteins|STAT1 protein, human|STAT1 Transcription Factor|Tumor Suppressor Proteins|Tyrosine | |
10935626 Nature 2000 Animals|Notch Receptors|*Glycosyltransferases|Drosophila|Drosophila Proteins|Fucose|N-Acetylglucosaminyltransferases|Membrane Proteins|Protein Binding|Glycosylation|Epidermal Growth Factor|Signal Transduction|notch protein, Drosophila | |
10935637 Nature 2000 Animals|Receptors, Notch|Drosophila Proteins|Drosophila|Fucose|N-Acetylglucosaminyltransferases|Membrane Proteins|Glycosyltransferases|Glycosylation|Epidermal Growth Factor|Ligands|Golgi Apparatus|Protein Binding|Signal Transduction|notch protein, Drosophila | |
10936461 Micron 2000 *Microfibrils|Fibrillin|*Extracellular Matrix|Fibrillin-1|Marfan Syndrome|Connective Tissue|Extracellular Matrix Proteins|Microfilament Proteins|Elasticity|Lens, Crystalline|Xray Diffraction | |
10938017 Arterioscler. Thromb. Vasc. Biol. 2000 Humans|oxidized low density lipoprotein|*Nuclear Factor-Kappab|*Lipoproteins, LDL|*CD36 Antigens|*Monocyte-Derived Macrophages|Monocytes|Scavenger Receptor|Cytokines|mRNA|Atherosclerosis|Lipopolysaccharides|Tumor Necrosis Factor-alpha|Cell Differentiation|Cells, Cultured|Signal Transduction | |
10938085 J. Biol. Chem. 2000 Mice|Animals|NIH 3T3 Cells|*Cell Differentiation|Transcription Factors|Homeodomain Proteins|Islets of Langerhans|Promoter Regions, Genetic|Transcription, Genetic|Pancreas|Insulin-Secreting Cells|Gene Expression Regulation, Developmental|*Organogenesis|Electrophoretic Mobility Shift Assay|mRNA | |
10938105 Mol. Cell. Biol. 2000 PMC86103 Animals|*RNA Splice Sites|TIA1 protein, human|*T-Cell Intracellular Antigen-1|*Introns|*RNA Splicing|U1 snRNP|Pre-mRNA|Exon|Alternative Splicing|Poly(A)-Binding Proteins|RNA-Binding Proteins|Binding Sites|Protein Binding|Base Sequence|FGFR2 protein, human|Receptor, Fibroblast Growth Factor, Type 2|Membrane Proteins | |
10938124 Mol. Cell. Biol. 2000 PMC86122 *Recombinational DNA Repair|RAD51 Protein|DNA Repair|DNA-Binding Proteins|DNA Damage|Sister Chromatid Exchange|Saccharomyces cerevisiae Proteins|Chromosomal Aberrations|Cell Division|DNA|Gamma Rays|Cloning, Molecular|Gene Targeting|Chromosome|Sequence Homology, Amino Acid|Amino Acid Sequence | |
10938287 J. Biol. Chem. 2000 Humans|Thermus aquaticus|G-T mismatch-binding protein|*DNA-Binding Proteins|*DNA|Base Pair Mismatch|MutS DNA Mismatch-Binding Protein|*Mutation|DNA Repair|Adenosine Triphosphatases|MutS Homolog 2 Protein|Escherichia coli Proteins|Dimerization|Amino Acid Sequence|Thermus|Protein Binding | |
10940294 J. Biol. Chem. 2000 Humans|Mice|Animals|*Serum Response Element|RTKN protein, human|*Signal Transduction|RHOA protein, human|rhoA GTP-Binding Protein|Protein Binding|Protein-Serine-Threonine Kinases|Amino Acid Sequence|*Transcription Factors|Sequence Homology, Amino Acid | |
10940339 Annu. Rev. Nutr. 2000 Humans|*Sterol Esterase|*Lipolysis|Adipose Tissue|Lipid Metabolism|Obesity|Fatty Acids|Signal Transduction | |
10940626 Mech. Dev. 2000 Humans|Mice|Animals|CDX1 protein, human|Homeodomain Proteins|Enhancer Elements, Genetic|Transcription Factors|Retinoic Acid|Mice, Transgenic|Gene Expression Regulation, Developmental|Transgene|Base Sequence|Nervous System|Mutations|Binding Site|Response Elements | |
10940905 Eur. J. Immunol. 2000 Humans|Receptors, Immunologic|Membrane Glycoproteins|Antigens, Differentiation|Receptors, Cell Surface|Signal Transduction|Adaptor Proteins, Signal Transducing|Neural Cell Adhesion Molecules|Neural Cell Adhesion Molecule L1|Carrier Proteins|Protein-Tyrosine Kinases|Phosphorylation|Monocytes|Isoforms|Protein Tyrosine Phosphatase, Non-Receptor Type 11 | |
10942115 Hum. Genet. 2000 Humans|Infant, Newborn|*Tyrosinemias|*4-Hydroxyphenylpyruvate Dioxygenase|*Mutations|Homozygote|Polymerase Chain Reaction|Neonatal Screening|Tyrosine | |
10942416 Blood 2000 Pregnancy|Child|Humans|Infant|Female|*Acidosis, Renal Tubular|Cesarean Section|*Spherocytosis, Hereditary|Anion Exchange Protein 1, Erythrocyte|GYPA protein, human|Glycophorin A|Erythrocytes|Ankyrin|Pedigree|Mutation | |
10944113 EMBO J. 2000 PMC302039 VHL protein, human|*Von Hippel-Lindau Tumor Suppressor Protein|Nuclear Proteins|HIF1A protein, human|*Hypoxia-Inducible Factor 1, alpha Subunit|Trans-Activators|Ligases|Protein Binding|Hypoxia|Binding Site|Proteasome Endopeptidase Complex|Oxygen | |
10944123 EMBO J. 2000 PMC302040 Cricetinae|Animals|*Glycosylphosphatidylinositols|dolichyl-phosphate beta-D-mannosyltransferase|Mannosyltransferases|Dolichol Monophosphate Mannose|Amino Acid Sequence|Base Sequence|Membrane Proteins|Sequence Alignment|Endoplasmic Reticulum|Cloning, Molecular|Sequence Homology, Amino Acid|Phosphatidylinositol|Transfection|CHO Cells | |
10944457 Biochem. Biophys. Res. Commun. 2000 Humans|leptin receptor, human|*Receptors, Leptin|*Leptin|G CSF Receptor|Amino Acid Sequence|*Models, Chemical|Granulocyte Colony-Stimulating Factor|Binding Sites|Protein Binding|Crystallography, X-Ray|Sequence Homology, Amino Acid|*Molecular Dynamics Simulation|Structural Model|Amino Acids | |
10944529 J. Biol. Chem. 2000 *Tetratricopeptide Repeat|*DNA Repair|*DNA|Transcription, Genetic|Transcription Factors|DNA-Binding Proteins|RNA Polymerase II|Protein Binding|Two-Hybrid System Techniques|DNA, Complementary|Gene Library|Binding Sites|Amino Acid Sequence|Blotting, Northern|Sequence Homology, Amino Acid|Cell Line|Immunoprecipitation | |
10944533 J. Biol. Chem. 2000 Animals|*Axin Protein|*Wnt Signaling Pathway|Glycogen Synthase Kinase 3 beta|CTNNB1 protein, human|beta Catenin|Wnt Proteins|Adenomatous Polyposis Coli Protein|Trans-Activators|Repressor Proteins|Xenopus Proteins|Protein Binding|Zebrafish Proteins|Phosphorylation|Adaptor Proteins, Signal Transducing|Calcium-Calmodulin-Dependent Protein Kinases|Carrier Proteins|Proto-Oncogene Proteins|Body Patterning | |
10945627 Cancer Res. 2000 Humans|Rats|Animals|tretazicar|*Prodrugs|*NAD|*Aziridines|NQO1 protein, human|DT Diaphorase|nicotinamide-beta-riboside|Nicotinamide|quinone|Benzoquinones|Quinones|Antineoplastic Agents|Tumor Cell Lines|Transfections | |
10945867 J. Pharmacol. Exp. Ther. 2000 Humans|Rats|Animals|*Nicotine|Nicotinic Antagonists|Nicotinic Agonists|Nicotinic Receptors|alpha7 Nicotinic Acetylcholine Receptor|AR-R 17779|Spiro Compounds|Bridged-Ring Compounds|methyllycaconitine|Aconitine|*Reward|Pyridines|Dihydro-beta-Erythroidine|Central Nervous System Stimulants|Neurons | |
10947204 J. Inherit. Metab. Dis. 2000 Humans|Methylmalonate Semialdehyde Dehydrogenase Deficiency|*Methylmalonate-Semialdehyde Dehydrogenase (Acylating)|*Amino Acid Metabolism, Inborn Errors|*Purine-Pyrimidine Metabolism, Inborn Errors|Aldehyde Oxidoreductases|L Valine|Homozygote|3-hydroxyisobutyric acid|Hydroxybutyrates|beta-Alanine | |
10947946 Am. J. Hum. Genet. 2000 PMC1287888 Humans|Free sialic acid storage disease|*Sialic Acid Storage Disease|*N-Acetylneuraminic Acid|*Mutations|sialic acid transport proteins|Organic Anion Transporters|Phenotype|Symporters|*Genotype-Phenotype Correlation|Heterozygote|Homozygote|Alleles|Exon|Intron|Finland|Sweden|Europe | |
10947957 Biochem. J. 2000 PMC1221270 Animals|Humans|Female|Pregnancy|sphingosine kinase|Escherichia coli|*Phosphotransferases (Alcohol Group Acceptor)|*Cloning, Molecular|sphingosine 1-phosphate|Lysophospholipids|Sphingosine|Amino Acid Sequence|Kinetics|Substrate Specificity|Recombinant Proteins|Gel Filtration Chromatography|Mutagenesis, Site-Directed|Catalysis|Electrophoresis, Polyacrylamide Gel|Blotting, Western | |
10948193 J. Biol. Chem. 2000 Animals|Chlorocebus aethiops|Humans|nucleoside triphosphate diphosphohydrolase 6|*Pyrophosphatases|ectoATPase|ATPases|Apyrase|Amino Acid Sequence|Glycosylation|cDNA|COS-1 Cells|Hydrolysis|Transfections|Cell Membranes | |
10949025 Mol. Cell 2000 Animals|*Geum|APAF1 protein, human|*Apoptotic Protease-Activating Factor 1|bcl-X Protein|Caspases|CASP9 protein, human|Caspase 9|Proto-Oncogene Proteins c-bcl-2|Apoptosis|Apoptosis Regulatory Proteins|bcl-2-Associated X Protein|*Protein Processing, Post-Translational|Carrier Proteins|Mitochondria|Enzyme Activation|*Cell Death|Signal Transduction | |
10949026 Mol. Cell 2000 *Phosphorylation|*14-3-3 Proteins|Proteins, BCL2|bcl-Associated Death Protein|bcl-X Protein|Apoptosis|Cell Survival|Carrier Proteins|Amino Acid Sequence|Serine|Mitochondria|Cell Line|Mutagenesis, Site-Directed|Transfection | |
10949031 Mol. Cell 2000 *Receptors, Interleukin-3|*Phosphorylation|*Cell Survival|Signal Transduction|Receptors, IL-5|sargramostim|Granulocyte-Macrophage Colony-Stimulating Factor|Receptors, Granulocyte-Macrophage Colony-Stimulating Factor|Phosphatidylinositol 3-Kinases|Phosphoproteins|Phosphoserine|Cell Line|Mutagenesis, Site-Directed|Transfection|Mutation | |
10949033 Mol. Cell 2000 Animals|Drosophila|Wnt1 Protein|Drosophila Proteins|Frizzled Receptors|Receptors, G-Protein-Coupled|Signal Transduction|Proto-Oncogene Proteins|Receptors, Neurotransmitter|Wings, Animal|Membrane Proteins|Genes, Insect|Gene Expression Regulation, Developmental|Mutation|Eye|Phenotype | |
10949035 Mol. Cell 2000 Humans|*Catalytic Domain|*Glycogen Phosphorylase, Liver Form|*Protein Structure, Secondary|Protein Conformation|Phosphorylases|Binding Sites|Models, Molecular|Allosteric Regulation|Crystallography, X-Ray|Glycogen|glucose-1-phosphate|Glucosephosphates|Muscles|Adenosine Monophosphate|Isoenzymes|Liver | |
10949293 Nature 2000 Humans|Mice|Animals|*Histone H3 Methyltransferase|*Histones|Chromatin|Methylation|Histone-Lysine N-Methyltransferase|Lysine|Repressor Proteins|Substrate Specificity|Amino Acid Sequence|Gene Expression Regulation|Phosphorylation | |
10950869 Genes Dev. 2000 PMC316859 *Cytochromes c|*Carrier Proteins|*Apoptosis Regulatory Proteins|bcl-2 Homologous Antagonist-Killer Protein|BH3 Interacting Domain Death Agonist Protein|bcl-2-Associated X Protein|Proto-Oncogene Proteins c-bcl-2|Mitochondria|Membrane Proteins|Apoptosis|*Ligands|Protein Binding|*Membrane | |
10950931 Genomics 2000 Animals|Humans|Mice|*Drosophila melanogaster|Drosophila Proteins|Amino Acid Sequence|Sequence Alignment|Membrane Proteins|Base Sequence|cDNA|Chromosome Mapping|Carrier Proteins|Sequence Homology, Amino Acid|Homology, Sequence|Caenorhabditis elegans|Chromosome|In Situ Hybridization, Fluorescence|TTYH1 protein, human|Ttyh1 protein, mouse | |
10951195 Eur. J. Biochem. 2000 Humans|Rats|Animals|*Insulin-Like Growth Factor Binding Protein 6|*Glycosylation|IGF2 protein, human|*Insulin-Like Growth Factor II|*Proteolysis|*Glycosaminoglycans|IGFBP|*Phosphorylation|*Protein Binding|Insulin-Like Growth Factor I|Amino Acid Sequence|Recombinant Proteins | |
10952395 Pigment Cell Res. 2000 dopaquinone|*Dihydroxyphenylalanine|eumelanin|Melanins|*Benzoquinones|phaeomelanin|Cysteinyldopa|*Redox|Tyrosinase|dopachrome|Indolequinones|Tyrosine|Cysteine|Pulse Radiolysis|Kinetics | |
10952898 Development 2000 Animals|Hedgehog Proteins|*Signal Transduction|Drosophila Proteins|Transcription Factor|Kinesin|Drosophila melanogaster|DNA-Binding Proteins|Repressor Proteins|Gene Expression Regulation, Developmental|Protein-Serine-Threonine Kinases|Cell Nucleus|*Limb Deformities, Congenital|Phosphorylation | |
10953014 J. Cell Biol. 2000 PMC2175269 *Phosphorylation|EPS15 protein, human|*Adaptor Proteins, Signal Transducing|*Endocytosis|Phosphoproteins|EGFR protein, human|Epidermal Growth Factor Receptor|*Ligands|Clathrin|Intracellular Signaling Peptides and Proteins|Calcium-Binding Proteins|Phosphotyrosine|Tyrosine|CD71 antigen|Transferrin Receptor|Protein Binding|Antigens, CD | |
10954531 J. Virol. 2000 PMC116342 Humans|*HIV-1|*Reverse Transcription|strong-stop DNA|DNA, Viral|HIV Long Terminal Repeat|RNA, Viral|Nucleic Acid Conformation|RNA-Directed DNA Polymerase|Genome, Viral|Virus Replication|Base Sequence|Transcription, Genetic|Virions|DNA, Single-Stranded | |
10954605 Nucleic Acids Res. 2000 PMC110711 Humans|RPA1 protein, human|*Replication Protein A|HeLa Cells|*Cell Cycle|DNA Replication|*Cell Division|Single-Stranded DNA-Binding Protein|Chromatin|S Phase|DNA, Single-Stranded|Phosphorylation|Protein Binding|Immunoprecipitation|Nocodazole | |
10954706 J. Biol. Chem. 2000 Humans|KRT8 protein, human|*Keratin-8|*HSP40 Protein Family|HeLa Cells|*Cytoskeleton|KRT18 protein, human|Keratin-18|Intermediate Filaments|Molecular Chaperones|Keratins|Amino Acid Sequence|Heat Shock Protein|Intermediate Filament Proteins|Microtubules|*CD59 Antigens|Two-Hybrid Methods|Gene Library | |
10954726 J. Biol. Chem. 2000 Chlorocebus aethiops|Humans|Animals|Mice|long-chain-fatty-acid-CoA ligase|Drosophila melanogaster|bile acid-CoA ligase|*Synthetases, Acyl CoA|Saccharomyces cerevisiae Proteins|Blotting, Northern|Amino Acid Sequence|COS-1 Cells|Acids, Fatty|cDNA|Transfections|Cloning, Molecular|Repressor Proteins | |
10954748 Proc. Natl. Acad. Sci. U.S.A. 2000 PMC27645 Animals|Mice|*Platelet Activation|*Signal Transduction|Platelet Aggregation|*Blood Platelet Disorders|Platelets|Heterotrimeric G-Proteins|GTP-Binding Protein alpha Subunits, Gi-Go|Adenosine Diphosphate|Cyclic AMP|Thrombin|Epinephrine|*Psychoactive Drugs | |
1095581 J. Biol. Chem. 1975 Animals|Rabbits|*Reticulocytes|*Initiation Factor|Ribosomes|Peptide Chain Initiation, Translational|Amino Acids|Guanosine Triphosphate|Molecular Weight|Electrophoresis, Polyacrylamide Gel|Chromatography, Ion Exchange|Chromatography, DEAE-Cellulose|mRNA | |
10956649 J. Biol. Chem. 2000 *Amyloid Precursor Protein Secretases|*Furin|*Alzheimer Disease|Aspartic Acid Endopeptidases|Amyloid beta-Protein Precursor|Cell Line|Amino Acid Sequence|SERPINA1 protein, human|alpha 1-Antitrypsin | |
10956669 J. Biol. Chem. 2000 Humans|*HIV Reverse Transcriptase|*RNase H|*RNAse H, HIV|RNA, Viral|DNA, Viral|HIV-1|Viral Genome|Base Sequence | |
10958654 Hum. Mol. Genet. 2000 Humans|Adenylosuccinate lyase deficiency|*Adenylosuccinate Lyase|*Purine-Pyrimidine Metabolism, Inborn Errors|*Autistic Disorder|Aminoimidazole Carboxamide|Ribonucleotides|Mutations|adenylosuccinate|Adenosine Monophosphate|Homozygote|succinyladenosine|Adenosine|Phenotype|Chromatography, High Pressure Liquid|Mutation, Missense|Psychomotor Disorders | |
10958673 Mol. Cell. Biol. 2000 PMC86199 Humans|Animals|*Proteolysis|*Unfolded Protein Response|Transcription Factor|DNA-Binding Proteins|XBP1 protein, human|X-Box Binding Protein 1|Endoplasmic Reticulum|Molecular Chaperones|Activating Transcription Factor 6|Membrane Proteins|Heat-Shock Proteins|Binding Protein|Protein Folding|Transcription Factor CHOP|*Regulatory Sequences, Nucleic Acid|Endoplasmic Reticulum Stress|Promoter Regions, Genetic|Regulatory Factor X Transcription Factors | |
10958683 Mol. Cell. Biol. 2000 PMC86228 Animals|*Formins|Contractile Proteins|Profilin|Microfilament Proteins|*Cell Motility|Actin Cytoskeleton|Actins|Fetal Proteins|rho GTPases|Amino Acid Sequence|Nuclear Proteins|Carrier Proteins|Cell Adhesion|Fungal Proteins|Sequence Homology, Amino Acid|Protein Structure, Tertiary|*Macrophages | |
10958687 Mol. Cell. Biol. 2000 PMC88767 JAG1 protein, human|*Jagged-1 Protein|NOTCH2 protein, human|*Receptor, Notch2|JAG2 protein, human|*Serrate-2 Protein|Serrate-Jagged Proteins|Notch Receptors|Ligands|Receptor, Notch1|Membrane Proteins|Intercellular Signaling Peptides and Proteins|Calcium-Binding Proteins|Transcription Factors|Intracellular Signaling Peptides and Proteins|Signal Transduction|Cell Differentiation|*Protein Transport | |
10958785 Science 2000 *Axons|Ephrin-A2|Cell Surface Proteins|Ligands|Cell Membrane|Transcription Factors|Signal Transduction|Receptor Protein-Tyrosine Kinases|Amino Acid Sequence | |
10959836 Curr. Biol. 2000 H2AX protein, human|*Histones|*DNA Damage|*Cell Nucleus|DNA Repair|DNA-Binding Proteins|Nuclear Proteins|Cell Cycle Proteins|Phosphorylation|BRCA1 Protein | |
10959839 Curr. Biol. 2000 *Proliferating Cell Nuclear Antigen|*DNA Ligase ATP|Okazaki fragments|*DNA|*Base Excision Repair|DNA Replication|DNA Ligases|Protein Binding|Binding Sites|Motif, Amino Acid|Pol beta protein, human|DNA Polymerase beta | |
10963998 Matrix Biol. 2000 *Glypicans|*Decorin|dermatan sulfate chondroitin sulfate|Dermatan Sulfate|Heparitin Sulfate|Chondroitin Sulfates|Heparan Sulfate Proteoglycans|glycosaminoglucuronates|Glycosaminoglycans|O-beta-galactopyranosyl-(1-4)-O-beta-xylopyranosyl-(1-0)-serine|Disaccharides|Oligosaccharides|Cell Line|Serine | |
10964718 Biochem. Biophys. Res. Commun. 2000 Mice|Humans|Animals|Transcription Factors|*Promoter Regions, Genetic|Basic Helix-Loop-Helix Transcription Factors|Notch Receptors|Binding Sites|Repressor Proteins|Transcription, Genetic|Nuclear Proteins|Base Sequence|Signal Transduction|Amino Acid Sequence|Membrane Proteins|Regulatory Region|Transcription Initiation Site|HEY1 protein, human|Cell Cycle Proteins|Hey1 protein, mouse | |
10964917 J. Biol. Chem. 2000 Animals|Mice|*Phosphorylation|*Protein Binding|*Platelet|*Signal Transduction|Platelet Aggregation|alphaIIbbeta3, Integrin|GRB2 Adaptor Protein|Shc Signaling Adaptor Proteins|Amino Acid Sequence|Adaptor Proteins, Vesicular Transport|Binding Site|Phosphotyrosine|Tyrosine|Src Homology 2 Domain-Containing, Transforming Protein 1|Peptides|Thrombin | |
10966108 Cell 2000 Humans|*DNA Repair|Acetylase, Histone|DNA Damage|Chromatin|*Cell Nucleus|Histones|Acetylation|DNA Helicases|Double-Strand DNA Break|ATPase|Saccharomyces cerevisiae Proteins|*Apoptosis|HeLa Cells|Protein Processing, Post-Translational|DNA | |
10966113 Cell 2000 Animals|Hedgehog Proteins|SMO protein, human|*Smoothened Receptor|PTCH protein, human|*Patched-1 Receptor|Signal Transduction|Receptors, G-Protein-Coupled|Drosophila Proteins|Receptors, Cell Surface|Drosophila|Integral Membrane Proteins|smoothened protein, Drosophila | |
10966456 Annu. Rev. Biochem. 2000 PTGS1 protein, human|Cyclooxygenase 1|Anti-Inflammatory Agents, Non-Steroidal|Inhibitors, COX2|Cyclooxygenase 2|Ibuprofen|Aspirin|PGH(2)|Kinetics|Isoenzymes|*Molecular Biology | |
10966616 Nat. Neurosci. 2000 Mice|Animals|cardiotrophin-like cytokine|*Receptors, Cytokine|Ciliary Neurotrophic Factor Receptor|*Cytokines|LIFR protein, human|Leukemia Inhibitory Factor Receptor alpha Subunit|STAT3 protein, human|Signal Transducer and Activator of Transcription 3|Cytokine Receptor gp130|Leukemia Inhibitory Factor Receptor|Ciliary Neurotrophic Factor|*Cell Membrane|Signal Transduction|*Ligands|Protein Binding|Cell Differentiation|Motor Neuron | |
10966814 J. Mol. Biol. 2000 Animals|*Endostatins|Vascular Endothelial Growth Factor A|*Tissue Distribution|Collagen XVIII|*Collagen|Vascular Endothelial Growth Factors|Angiogenesis Inhibitors|Neovascularization, Pathologic|Neovascularization, Physiologic|Peptide Fragments|Extracellular Matrix Proteins|Heparin|Endothelium, Vascular|Cytokines|Neoplasms | |
10966924 Am. J. Physiol. Renal Physiol. 2000 Humans|Animals|Mice|*Kidney|Organic Cation Transporter 1|Organic Cation Transport Proteins|Tetraethylammonium|Amino Acid Sequence|Membrane Proteins|Xenopus laevis|Biological Transport|mRNA|Cloning, Molecular|Blotting, Northern|1-Methyl-4-phenylpyridinium|In Situ Hybridization|Oocytes|Cations | |
10969042 Circ. Res. 2000 Humans|Male|Cricetinae|Animals|ACE protein, human|angiotensin converting enzyme 2|*Peptidyl-Dipeptidase A|*Angiotensin I|Renin-Angiotensin System|Angiotensin-Converting Enzyme Inhibitors|Captopril|Carboxypeptidases|Lysinopril|AGT protein, human|*Angiotensinogen|Kidney|Amino Acid Sequence|CHO Cells|Hydrolysis | |
10970790 Biochem. J. 2000 PMC1221308 Male|Humans|*DNA, Complementary|Saccharomyces cerevisiae|docosapentaenoic acid|Fatty Acids, Unsaturated|Amino Acid Sequence|Cloning, Molecular|Base Sequence|*Fatty Acids|adrenic acid|PCR|Fungal Proteins|Open Reading Frame|Sequence Homology, Amino Acid | |
10970791 Biochem. J. 2000 PMC1221309 Humans|*Sugar|Glucose Transporter|Amino Acid Sequence|Monosaccharide Transport Proteins|cDNA|*Genomics|Cytochalasin B|Exons|Biological Transport|Cloning, Molecular|Glucose|Introns|Sequence Homology, Amino Acid|Transfection|RNA, Messenger|*Leukocytes|*Facilitated Diffusion|*Brain | |
10970870 EMBO J. 2000 PMC302067 Humans|Mice|Animals|*Elongation Factor|HeLa Cells|*Selenoprotein|Selenocysteine|RNA, Transfer, Amino Acyl|Protein Biosynthesis|UGA Codons|Ribosome|Amino Acid Sequence|mRNA|Bacterial Proteins|tRNA|Guanosine Triphosphate|*Mammals|Nucleic Acid Conformation|Escherichia coli | |
10972280 Nature 2000 Caspases|Protein, Mitochondrial|CASP3 protein, human|Caspase 3|X-Linked Inhibitor of Apoptosis Protein|Apoptosis|Carrier Proteins|Caspase 9|Inhibitor of Apoptosis Proteins|Intracellular Signaling Peptides and Proteins|Amino Acid Sequence|Caspase Inhibitors|Protein Binding|Sequence Homology, Amino Acid|Mitochondria|rpr protein, Drosophila|Drosophila Proteins | |
10973264 Nat. Genet. 2000 Humans|Mice|Animals|TP53 protein, human|*Tumor Suppressor Protein p53|*Apoptosis|DNA Damage|Blotting, Northern|Reporter Gene|*Protein Domain|Protein Binding|Cell Cycle|Carrier Proteins|Binding Sites|Transcription, Genetic|Cell Death|cDNA|RNA, Messenger|RNA|Blotting, Western|Transfection | |
10973490 Proc. Natl. Acad. Sci. U.S.A. 2000 PMC27034 Animals|*Ataxia Telangiectasia|*Phosphorylation|CHEK2 protein, human|CDS1 Kinase|Cell Cycle Proteins|Ataxia Telangiectasia Mutated Proteins|Tumor Suppressor Proteins|Protein Kinases|DNA Damage|Cell Cycle|DNA-Binding Proteins|Yeast, Fission|Ionizing Radiation | |
10973499 Proc. Natl. Acad. Sci. U.S.A. 2000 PMC27041 VHL protein, human|Von Hippel-Lindau Tumor Suppressor Protein|*Ubiquitination|Nuclear Proteins|Cullin 1|Cullin Proteins|Ubiquitin|Ubiquitins|HIF1A protein, human|*Hypoxia-Inducible Factor 1, alpha Subunit|Ligases|Proteasome|Genes, Tumor Suppressor|Protein Binding|Mutations | |
10973981 J. Biol. Chem. 2000 Humans|Animals|SLC5A1 protein, human|*Sodium-Glucose Transporter 1|*Sodium|GABA Plasma Membrane Transport Proteins|Biological Transport|Monosaccharide Transport Proteins|Xenopus laevis|N-(4,4-diphenyl-3-butenyl)nipecotic acid|Nipecotic Acids|Membrane Glycoproteins|Cell Membrane|Kinetics|gamma-Aminobutyric Acid|Ion Transport|*Ions|Oocytes|Organic Anion Transporters | |
10975528 Cell 2000 WAS protein, human|Wiskott-Aldrich Syndrome Protein|Protein Binding|p21-Activated Kinases|Amino Acid Sequence|Cell Cycle Proteins|Binding Sites|cdc42 GTP-Binding Protein|rac GTP-Binding Proteins|Ligands|Active Site | |
10975989 Cytokine 2000 Humans|*Monocytes|IL10 protein, human|*Interleukin-10|HEK293 Cells|CD163 antigen|*Antigens, Differentiation, Myelomonocytic|*Antigens, CD|*Receptors, Cell Surface|Macrophages|*Upregulation|Scavenger Receptor|Anti-Inflammatory Agents|Glucocorticoids|Flow Cytometries|*Transcriptional Activation|Cytokines | |
10978331 J. Biol. Chem. 2000 Female|Pregnancy|Cricetinae|Animals|Humans|CHO Cells|Chinese Hamster|*Mitochondria|Membrane Transport Proteins|cDNA|Mitochondrial Membrane Transport Proteins|*Folate|Amino Acid Sequence|cDNA Library|Cloning, Molecular|Membrane Proteins|*Phenotype|Expressed Sequence Tag|*Retroviridae | |
10978526 Biochim. Biophys. Acta 2000 Humans|Male|Animals|*Sodium-Bicarbonate Symporters|Cloning, Molecular|Amino Acid Sequence|Bicarbonates|Xenopus laevis|Sequence Homology, Amino Acid|Carrier Proteins|Spleen|Liver|Tissue Distribution|Oocytes|Testes|*Chromosome | |
10978532 Biochim. Biophys. Acta 2000 Mice|Animals|Humans|*DNA, Complementary|glycollate oxidase|*Alcohol Oxidoreductases|Amino Acid Sequence|Blotting, Northern|Sequence Alignment|Base Sequence|Cloning, Molecular|Sequence Homology, Amino Acid|Exons|Transfection|mRNA|Open Reading Frame|Liver | |
10980531 Hum. Mutat. 2000 Humans|Congenital disorder of glycosylation type 1B|*Mannose-6-Phosphate Isomerase|*Congenital Disorders of Glycosylation|*DNA Mutational Analysis|ATP8A2 protein, human|*Adenosine Triphosphatases|*Phospholipid Transfer Proteins|Glycosylation|*Genomics|Mutation|Mannose|DNA|Hepatic Fibrosis, Congenital|Transferrin|Glycoproteins|Mutations, Missense|Liver Cirrhosis | |
10980602 Oncogene 2000 *Ribonucleotide Reductase|*Tumor Suppressor Protein p53|DNA Repair|Cell Cycle Proteins|Cyclin-Dependent Kinase Inhibitor p21|DNA Damage|Tumor Protein p73|DNA-Binding Proteins|Nuclear Proteins|Cell Cycle|Cell Division|*Ribonucleotides|Apoptosis|Cell Line, Tumor|DNA|Transfection | |
10980695 Nat. Cell Biol. 2000 *Tumor Suppressor Protein p53|*Cell Nucleus|Proto-Oncogene Proteins c-mdm2|*RING Finger Domain|Cytoplasm|Export, Nuclear|Nuclear Proteins|Ubiquitin|Proto-Oncogene Proteins|Ubiquitins|Cell Line|Transfection|Amino Acid Sequence|Green Fluorescent Proteins|Tumor Cells, Cultured | |
10980696 Nat. Cell Biol. 2000 *Active Transport, Cell Nucleus|*Tumor Suppressor Protein p53|Proto-Oncogene Proteins c-mdm2|*RING Finger Domain|Cell Nucleus|Cytoplasm|Nuclear Proteins|Ubiquitin|Signal, Nuclear Export|Proto-Oncogene Proteins|Ubiquitins|Transfections|Proteasome|Mutation|Cell Line|Tumor Cells, Cultured|Protein Binding | |
10982 Biochim. Biophys. Acta 1976 *Superoxides|*Cytochromes c|*Kinetics|Superoxide Dismutase|Ionic Strength|Oxidation-Reduction|Hydrogen-Ion Concentration|*Anions|Oxygen|Thermodynamic|Temperature|*Physics|Copper | |
10982028 Hum. Genet. 2000 Humans|*Sandhoff Disease|Cyprus|Genetic Carrier Screening|beta-N-Acetylhexosaminidases|Heterozygote|Mutation|Intron|PCR|DNA | |
10982388 Mol. Biol. Cell 2000 PMC14963 *Integrin alpha3beta1|*Thrombospondin 1|*Endothelial Cell|Cell Adhesion|Signal Transduction|cadherin 5|Antigens, CD|Cell Movement|Neovascularization, Physiologic|Endothelium, Vascular|Peptides|Cell Division|Cell Proliferation|CD36 Antigens|Cadherins | |
10982397 Mol. Biol. Cell 2000 PMC14972 Animals|*Endoplasmic Reticulum|Golgi Apparatus|Nocodazole|Microtubules|Saccharomyces cerevisiae Proteins|Luminescent Proteins|Protein Transport|Membrane Proteins|Fluorescence Microscopy|Green Fluorescent Proteins|Membrane Glycoproteins|*Vertebrate | |
10982817 J. Biol. Chem. 2000 Animals|Mice|*src Homology Domain|*Binding Proteins|Endosomal Sorting Complexes Required for Transport|Protein Binding|Binding Sites|Phosphoproteins|Amino Acid Sequence|Adaptor Proteins, Signal Transducing|Ubiquitin|Ubiquitin Thiolesterase|Endopeptidases|cDNA|Models, Molecular|Protein Transport | |
10982827 Mol. Cell. Biol. 2000 PMC86258 *Phosphatidylinositol 3-Kinase|*Proto-Oncogene Proteins c-akt|GAB2 protein, human|GRB2 protein, human|GRB2 Adaptor Protein|Phosphorylation|SH3 Domains|Shc Signaling Adaptor Proteins|Protein Binding|Phosphatidylinositol 3-Kinases|Adaptor Proteins, Vesicular Transport|Signal Transduction|Proto-Oncogene Proteins|Phosphoproteins|Src Homology 2 Domain-Containing, Transforming Protein 1|Receptor Protein-Tyrosine Kinases|Tyrosine|Binding Sites | |
10982836 Mol. Cell. Biol. 2000 PMC86273 Humans|Mice|Animals|Atf2 protein, mouse|ATF2 protein, human|*Activating Transcription Factor 2|*Amino Acids|*Promoter Regions, Genetic|CCAAT Enhancer Binding Protein|Transcription, Genetic|Activation, Transcriptional|Cyclic AMP Response Element-Binding Protein|Gene Expression Regulation|Nuclear Proteins|Binding Sites|Response Element|Transcription Factor CHOP|*Mammals|Phosphorylation|Transfection|RNA, Messenger | |
10982844 Mol. Cell. Biol. 2000 PMC86281 JAK1 protein, human|*Janus Kinase 1|*Signal, Nuclear Export|*Active Transport, Cell Nucleus|TYK2 Kinase|Phosphorylation|STAT1 Transcription Factor|Trans-Activators|Signal Transduction|Cell Nucleus|Tyrosine | |
10982855 Mol. Cell. Biol. 2000 PMC86292 Rats|Male|Animals|Humans|FGFR2 protein, human|*Receptor, Fibroblast Growth Factor, Type 2|*Polypyrimidine Tract-Binding Protein|*Exon|*Introns|*RNA Splicing|Alternative Splicing|Base Sequence|Silencer Element|Transfection|Mutations|Isoforms|Cell Line|*Prostatic Neoplasms | |
10982862 Nucleic Acids Res. 2000 PMC110725 Female|Pregnancy|Humans|Mice|Animals|N(2),N(2)-dimethylguanosine|N(2),N(2)-dimethylguanosine-26-methyltransferase|tRNA Methyltransferases|*tRNA|*Cloning, Molecular|Guanosine|Recombinant Proteins|Base Sequence|Saccharomyces cerevisiae|Amino Acid Sequence|Escherichia coli|Nucleic Acid Conformation|RNA|Point Mutations | |
10983975 Mol. Cell 2000 *Protein Kinase|*tRNA|Saccharomyces cerevisiae Proteins|Saccharomyces cerevisiae|Phosphorylation|Ribosome|Histidyl-tRNA Synthetase|DNA-Binding Proteins|Protein-Serine-Threonine Kinases|Eukaryotic Initiation Factor-2|Protein Biosynthesis|Protein Binding|Sequence Homology, Amino Acid|GCN2 protein, S cerevisiae | |
10983984 Mol. Cell 2000 *Phosphoinositides|*Pleckstrin Homology Domains|Phosphatidylinositol Phosphates|Inositol Phosphates|Phosphoproteins|Phosphoinositide 3 Kinases|Binding Sites|Blood Proteins|Amino Acid Sequence|Sequence Homology, Amino Acid | |
10983987 Mol. Cell 2000 Humans|*Proteasome Endopeptidase Complex|Saccharomyces cerevisiae|Saccharomyces cerevisiae Proteins|Ubiquitins|*Ubiquitination|Cell Cycle Proteins|Ubiquitin|Polyubiquitin|Ligases|Protein Subunits|Cysteine Endopeptidases|Binding Site|DSK2 protein, S cerevisiae | |
10984056 Nature 2000 Humans|cyclopamine|Hedgehog Proteins|*Veratrum Alkaloids|SMO protein, human|*Smoothened Receptor|PTCH protein, human|*Patched-1 Receptor|Patched Receptors|Medulloblastoma|Basal Cell Carcinoma|Signal Transduction|Receptors, G-Protein-Coupled|Receptors, Cell Surface|Rhabdomyosarcoma|Trans-Activators|Cell Proliferation|Intracellular Signaling Peptides and Proteins|Membrane Proteins | |
10984059 Nature 2000 Humans|DNA polymerase zeta|DNA Polymerases|Rad30 protein|DNA polymerase iota|*DNA|Mutagenesis|DNA Damage|Pyrimidine Dimers|Saccharomyces cerevisiae|*Eukaryotic Cells | |
10984481 J. Biol. Chem. 2000 Humans|Male|*Prostate|*Prostate Cancer|Immediate-Early Proteins|Oligonucleotide Arrays|Early Growth Response Protein 1|Gene Expression Regulation, Neoplastic|IGF2 protein, human|Insulin-Like Growth Factor II|EGR1 protein, human | |
10984493 J. Biol. Chem. 2000 Humans|*Ultraviolet Rays|*Tumor Suppressor Protein p53|DNA-Binding Proteins|Transcription Factors|DNA Damage|Transcription, Genetic|DNA Repair|Promoter Regions, Genetic|Transcriptional Activation|Up-Regulation | |
10985348 Neuron 2000 Rats|Animals|*Receptor, Nerve Growth Factor|NGF protein, human|*Nerve Growth Factor|*Apoptosis|Receptor, trkA|MAGED1 protein, human|Neoplasm Proteins|Signal Transduction|Receptors, Nerve Growth Factor|Neurons|PC12 Cells|Antigens, Neoplasm | |
10986281 J. Biol. Chem. 2000 BCAN protein, human|*Brevican|*ADAMTS4 Protein|*Matrix Metalloproteinases|Procollagen N-Endopeptidase|Chondroitin Sulfate Proteoglycans|Proteoglycan|Aggrecan|ADAM Proteins|Extracellular Matrix Proteins|MMP1 protein, human|Matrix Metalloproteinase 1|Amino Acid Sequence|Nerve Tissue Proteins|Molecular Weight | |
10986460 Structure 2000 Humans|*Interferon-gamma|Receptors, Interferon|Protein Conformation|Protein Binding|Crystallography, X-Ray|Amino Acid Sequence|Binding Sites|Models, Molecular|Cytokines|Cell Signaling | |
10987144 Mol. Cells 2000 Animals|Humans|Sheep|*Pyridoxal Kinase|Escherichia coli|Protein Folding|Circular Dichroism|Protein Denaturation|Protein Conformation|Guanidine Hydrochloride|Recombinant Proteins|Kinetics|Catalysis|Dimerization|Phosphorylation | |
10987279 Cancer Res. 2000 Humans|Carcinoma, Renal Cell|Kidney Neoplasms|*Adenocarcinoma, Clear Cell|DNA-Formamidopyrimidine Glycosylase|DNA Repair|*Kidney|Polymorphism, Genetic|Alleles|N-Glycosyl Hydrolases|Loss of Heterozygosity|Heterozygote|Codon | |
10987286 Cancer Res. 2000 Animals|Humans|multidrug resistance protein 3|HEK293 Cells|multidrug resistance-associated protein 2|Multidrug Resistance-Associated Proteins|*ATP Binding Cassette Transporter, Subfamily B|multidrug resistance-associated protein 1|ATP-Binding Cassette Transporters|Drug Resistance, Multiple|Biological Transport|Membrane Transport Proteins|MgATP|Glutathione|Leukotriene C4|Bile Acids and Salts|Anticancer Agents|Glucuronides|Cell Membrane|Methotrexate | |
10987651 Hum. Genet. 2000 Animals|*Phosphorylase Kinase|*Fanconi Syndrome|Glycogen Storage Disease Type Ix|*Glycogenosis|*Mutation|*Liver|SLC2A2 protein, human|*Glucose Transporter Type 2|Homozygote|*Fanconi Anemia|Amino Acid Sequence|Missense Mutation|Glycogen | |
10988300 J. Biol. Chem. 2000 Humans|N-acetylgalactosamine-4-sulfotransferase|*Acetylgalactosamine|*Sulfotransferases|*Cloning, Molecular|HNK-1 sulfotransferase|CHST11 protein, human|*Pituitary Diseases|*Pituitary Gland|cDNA|Amino Acid Sequence|Base Sequence|Chromosome Mapping|Lutropin|Sulfates|Sequence Homology, Amino Acid|Oligosaccharides|Substrate Specificity|Thyrotropin | |
10990447 Growth Horm. IGF Res. 2000 Male|Humans|*PC-3 Cells|*Proteolysis|*Prostate|IGFBP3 protein, human|Insulin-Like Growth Factor Binding Protein 3|IGF2 protein, human|IGF-2|Plasmin|*Prostatic Neoplasms|*Recombinant Proteins|IGFBP|Receptor, IGF Type 1|*Cell Proliferation|Cell Division|*Intercellular Signaling Peptides and Proteins|IGFBP5 protein, human|IGFBP-5|Mitogens | |
10990452 EMBO J. 2000 PMC314221 GOLPH3 protein, human|Golgi Apparatus|Saccharomyces cerevisiae Proteins|Vesicular Transport Proteins|Saccharomyces cerevisiae|SNARE|Endoplasmic Reticulum|Monomeric GTP-Binding Proteins|Membrane Fusion|Sequence Homology, Amino Acid|Protein Binding|Endosome|Mutation|Amino Acid Sequence|Guanine Nucleotide Exchange Factors|*Nucleotides|*Catalysis|YPT6 protein, S cerevisiae | |
10991949 J. Biol. Chem. 2000 Mice|Animals|*Receptors, Prolactin|*Tyrosine|GAB1 protein, human|*Adaptor Proteins, Signal Transducing|GAB2 protein, human|PTPN11 protein, human|*SHP-2 Protein-Tyrosine Phosphatase|SH2 Domain-Containing Protein Tyrosine Phosphatases|SH2 Domain|Phosphorylation|Signal Transduction|Phosphoproteins|Protein Binding|Protein Tyrosine Phosphatase, Non-Receptor Type 6|Cell Line|DNA-Binding Proteins|Prolactin|Carrier Proteins | |
10993717 Mol. Genet. Metab. 2000 Humans|Animals|Mice|*Farber Lipogranulomatosis|ASAH1 protein, human|*Acid Ceramidase|Ceramidases|Amidohydrolases|Lysosomal Storage Diseases|DNA Mutational Analysis|DNA|Exons|DNA, Complementary|Introns|mRNA|Mutation | |
10993888 J. Biol. Chem. 2000 Mice|Female|Animals|STAT5A protein, human|STAT5B protein, human|*STAT5 Transcription Factor|*Prolactin|Lactation|*Tumor Suppressor Proteins|JAK2 protein, human|Janus Kinase 2|*Protein Tyrosine Phosphatases, Non-Receptor|Phosphorylation|Signal Transduction|PTPN1 protein, human|*Protein Tyrosine Phosphatase, Non-Receptor Type 1|PTPN11 protein, human|Protein Tyrosine Phosphatase, Non-Receptor Type 11|Trans-Activators|DNA-Binding Proteins|Milk Protein | |
10993897 J. Biol. Chem. 2000 Mice|Animals|Humans|*cDNA|polypeptide N-acetylgalactosaminyltransferase|globotriaosylceramide|*Acetylgalactosamine|globoside alpha-N-acetylgalactosaminyltransferase|*N-Acetylgalactosaminyltransferases|*Uridine Diphosphate N-Acetylgalactosamine|*Cloning, Molecular|*Trihexosylceramides|Forssman Antigen|Amino Acid Sequence|Carbohydrate Sequence|Base Sequence|Globosides|UDP-galactose-lactosylceramide alpha 1-4-galactosyltransferase|Galactosyltransferases|cDNA Library|Sequence Homology, Amino Acid | |
10995389 Genes Dev. 2000 PMC316932 Humans|Animals|*Anaphase Promoting Complex|*Proteolysis|*Cell Cycle|Saccharomyces cerevisiae Proteins|Cell Cycle Proteins|DNA Replication|Ubiquitin-Protein Ligases|Saccharomyces cerevisiae|S Phase|Anaphase|Gene Expression Regulation, Fungal|G1 Phase|Replication Origins|Ubiquitins|CDH1 protein, human|*Cadherins|*Antigens, CD|CDC6 protein, human | |
10995434 J. Cell Biol. 2000 PMC2150706 *Mitochondria|Saccharomyces cerevisiae Proteins|Mitochondrial Membrane Transport Proteins|Carrier Proteins|Saccharomyces cerevisiae|Mitochondrial Proteins|Membrane Transport Proteins|Membrane Proteins|Biological Transport|Protein Binding|Mitochondrial Membranes | |
10995436 J. Cell Biol. 2000 PMC2150699 *Wiskott-Aldrich Syndrome Protein, Neuronal|*Phosphatidylinositol|Actin-Related Protein 3|Actin-Related Protein 2|Cytoskeletal Proteins|Filaments, Actin|Actins|Nerve Tissue Proteins|cdc42 GTP-Binding Protein|Phosphatidylinositol 4,5-Diphosphate|Signal Transduction|Binding Site|Protein Binding|Wiskott-Aldrich Syndrome | |
10995437 J. Cell Biol. 2000 PMC2150692 Cattle|Animals|WAS protein, human|*Wiskott-Aldrich Syndrome Protein|*Arp2-3 Complex|*Actins|Actin-Related Protein 3|Actin-Related Protein 2|Wiskott-Aldrich Syndrome Protein, Neuronal|Wiskott-Aldrich Syndrome|cdc42 GTP-Binding Protein|Nerve Tissue Proteins|Phosphatidylinositol 4,5-Diphosphate|Protein Binding|Binding Sites|Signal Transduction | |
10995764 J. Biol. Chem. 2000 *Phosphatidylinositol 3-Kinase|Phosphatidylinositol 3-Kinases|*Signal Transduction|GAB2 protein, human|GRB2 protein, human|GRB2 Adaptor Protein|Proto-Oncogene Proteins c-ret|GDNF protein, human|Glial Cell Line-Derived Neurotrophic Factor|Phosphorylation|Multiple Endocrine Neoplasia Type 2a|Glial Cell Line-Derived Neurotrophic Factor Receptors|Proto-Oncogene Proteins|Phosphoproteins|PTPN11 protein, human|SHP-2 Protein-Tyrosine Phosphatase|Proto-Oncogene Proteins c-akt|Shc Signaling Adaptor Proteins | |
10997929 Am. J. Physiol. Renal Physiol. 2000 Humans|Mice|Animals|CD2-associated protein|nephrin|*Podocytes|*Cytoskeletal Proteins|*Membrane Proteins|*Adaptor Proteins, Signal Transducing|Kidney Glomerulus|Nephrosis, congenital|Nephrotic Syndrome|Intercellular Junctions|Kidney|Kidney Tubules | |
11000521 Mol. Cell. Endocrinol. 2000 Humans|Mice|Animals|AKT1 protein, human|*Proto-Oncogene Proteins c-akt|IRS2 protein, human|*Insulin Receptor Substrate 2|*Phosphatidylinositol 3-Kinase|*NIH 3T3 Cells|*Signal Transduction|GRB2 protein, human|*Growth Factor Receptor-Bound Protein-2|Phosphorylation|Phosphatidylinositol 3-Kinases|Proto-Oncogene Proteins c-ret|Proto-Oncogene Proteins|Multiple Endocrine Neoplasia Type 2a|Glial Cell Line-Derived Neurotrophic Factor Receptors|Mitogen-Activated Protein Kinases|Shc Signaling Adaptor Proteins|Phosphoproteins | |
11001057 Nature 2000 Animals|*Glutamate Transporter|*Neurons|Glutamate|Synaptic Vesicles|GABA|Vesicular Glutamate Transport Protein 2|Vesicular Glutamate Transport Protein 1|Biological Transport|GABA Plasma Membrane Transport Proteins|Presynaptic Terminals|Vesicular Transport Proteins|Synapses|Organic Anion Transporters|Brain|*Phenotype | |
11001876 Biochem. J. 2000 PMC1221362 *Pleckstrin Homology Domain|platelet protein P47|Phosphatidylinositol 3-Kinases|phosphatidylinositol 4-phosphate|Phosphatidylinositol Phosphates|Phosphoproteins|Blood Proteins|phosphatidylinositol 3-phosphate|PtdIns|Protein Binding|Carrier Proteins|Amino Acid Sequence|Membrane Proteins|Adaptor Proteins, Signal Transducing|Protein Structure, Tertiary|Binding Sites|Sequence Homology, Amino Acid|Cloning, Molecular | |
11001937 Hum. Mol. Genet. 2000 Animals|Humans|Aquaporin 2|*Crystalline Lens|aquaporin 0|Cataract, zonular|*Cataracts|Eye Proteins|Aquaporin 1|Mutations, Missense|Amino Acid Sequence|*Lenses|Plasma Membrane|Protein Transport|Mutation|Xenopus laevis|Oocyte | |
11002417 Oncogene 2000 CASP8 protein, human|*Caspase 8|*NF-kappa B|Caspases|RELA protein, human|*Transcription Factor RelA|Caspase 9|CASP10 protein, human|Caspase 10|Serine-Threonine Kinases, RIP|Fas-Associated Death Domain Protein|CASP8 and FADD-Like Apoptosis Regulating Protein|TNF Receptor-Associated Factor 2|I-kappa B Kinase|Receptors, TNF-Related Apoptosis-Inducing Ligand|TNF Receptor-Associated Factor 1|Apoptosis|Receptors, Tumor Necrosis Factor, Type I | |
11002419 Oncogene 2000 Humans|GDNF protein, human|*Glial Cell Line-Derived Neurotrophic Factor|*Tyrosine|Signal Transduction|Glial Cell Line-Derived Neurotrophic Factor Receptors|Proto-Oncogene Proteins c-ret|GRB2 Adaptor Protein|Phosphorylation|Multiple Endocrine Neoplasia Type 2a|Mitogen-Activated Protein Kinases|Proto-Oncogene Proteins|*Cytoplasm|Phosphatidylinositol 3-Kinases|Shc Adaptor Proteins|Proto-Oncogene Proteins c-akt|Drosophila Proteins|Phosphoproteins|Binding Site | |
11002420 Oncogene 2000 oxoguanine glycosylase 1, human|*8-Hydroxy-2'-Deoxyguanosine|*Point Mutation|*DNA Glycosylases|DNA-Formamidopyrimidine Glycosylase|DNA Damage|DNA Repair|Deoxyguanosine|8-hydroxyguanine|Guanine|DNA|Mutation|Cell Line, Tumor | |
11003670 Mol. Cell. Biol. 2000 PMC86358 Mice|Animals|*S Phase|CDKN1A protein, human|Cyclin-Dependent Kinase Inhibitor p21|Transcription Factor DP1|Cell Cycle Proteins|E2F Transcription Factors|Retinoblastoma-Binding Protein 1|Retinoblastoma Protein|Cyclins|Cell Cycle|E2F1 Transcription Factor|Cyclin-Dependent Kinases|G1 Phase|DNA Replication|Cell Division|Phosphorylation|*DNA Damage | |
11004484 Biochim. Biophys. Acta 2000 Humans|*HL-60 Cells|*Receptors, Purinergic|CD39 antigen|Apyrase|P2 Receptors, Purinergic|NT5E protein, human|5'-Nucleotidase|Receptors, Purinergic P2X|Adenosine Triphosphate|Cell Differentiation|Antigens, CD|*Hematopoiesis|Cells, Cultured|mRNA|Calcium|GPI-Linked Proteins | |
11004490 Biochim. Biophys. Acta 2000 Male|Female|Humans|platelet-derived growth factor C|*Lymphokines|*Platelet-Derived Growth Factor|Vascular Endothelial Growth Factor A|Vascular Endothelial Growth Factors|cDNA|mRNA|Amino Acid Sequence|Uterus|Endometrium|Polymerase Chain Reaction|Fallopian Tube|*Reproduction | |
11005803 J. Biol. Chem. 2000 Humans|*Proliferating Cell Nuclear Antigen|*MutS Homolog 2 Protein|G-T mismatch-binding protein|*DNA-Binding Proteins|MSH3 protein, human|MutS Homolog 3 Protein|Saccharomyces cerevisiae|Saccharomyces cerevisiae Proteins|DNA, Fungal|Base Pair Mismatch|DNA Repair|Adenosine Triphosphatases|Protein Binding|DNA Mismatch Repair|Amino Acid Sequence|MSH2 protein, human|MSH3 protein, S cerevisiae | |
11006133 Biochem. Biophys. Res. Commun. 2000 JAG2 protein, human|*Serrate-2 Protein|JAG1 protein, human|*Jagged-1 Protein|NOTCH3 protein, human|*Notch3 Protein|Serrate-Jagged Proteins|Notch Receptors|Receptor, Notch2|Intercellular Signaling Peptides and Proteins|Membrane Proteins|Receptor, Notch1|Calcium-Binding Proteins|Ligands|Intracellular Signaling Peptides and Proteins|Transcription Factors|Cell Membrane|Cell Differentiation | |
11006276 J. Biol. Chem. 2000 Animals|Humans|POLK protein, human|*DNA-Directed DNA Polymerase|*DNA Replication|DNA Polymerase beta|DNA Repair|Mutagenesis|Base Pair Mismatch|DNA|Frameshift Mutation|Mutation|Models, Molecular|Kinetics | |
11007478 Cell 2000 Humans|*Molecular Structure|DNA Helicases|Transcription Factor TFIIH|CCNH protein, human|Cyclin H|DNA Repair|Transcription Factors|Cyclin-Dependent Kinases|Xeroderma Pigmentosum Group D Protein|Protein-Serine-Threonine Kinases|Transcription, Genetic|Protein Binding | |
11007481 Cell 2000 *Phosphorylation|VAV1 protein, human|*Proto-Oncogene Proteins c-vav|cdc42 GTP-Binding Protein|Proto-Oncogene Proteins|Cell Cycle Proteins|rho GTPases|rhoA GTP-Binding Protein|rac1 GTP-Binding Protein|src-Family Kinases|Guanosine Triphosphate|Amino Acid Sequence|Tyrosine|Proto-Oncogenes | |
11007482 Cell 2000 *src Tyrosine Kinases|Protein Tyrosine Kinase|Phosphorylation|Proto-Oncogene Proteins c-hck|Signal Transduction|src Homology Domains|Proto-Oncogene Proteins|Enzyme Activation|Protein Binding|GTP-Binding Protein alpha Subunits, Gi-Go|Downregulation|Heterotrimeric G-Proteins|Cell Line | |
11007799 J. Biol. Chem. 2000 Rats|Humans|Animals|9-cis-retinal|*DNA, Complementary|*Retinaldehyde|ALDH1A1 protein, human|*Aldehyde Dehydrogenase|ALDH1A2 protein, human|Retinal Dehydrogenase|Amino Acid Sequence|Base Sequence|Cloning, Molecular|retinol dehydrogenase 5|Alcohol Oxidoreductases|Tretinoin|Substrate Specificity|9-cis-Retinoic Acid|RNA, Messenger|Retinol|RALDH1 protein, rat | |
11007890 J. Neurosci. 2000 PMC6772792 Rats|Animals|NGF protein, human|*Nerve Growth Factor|*Clathrin|Receptor, trkA|*Protein Transport|PC12 Cells|*Plasma Membrane|Receptors, Nerve Growth Factor|Neurons|Receptor, Nerve Growth Factor|Signal Transduction|Endosomes|Hippocampus|Phosphorylation | |
11007921 Stem Cells 2000 Humans|*Stem Cell Factor|EPO protein, human|*Erythropoietin|STAT5A protein, human|STAT5 Transcription Factor|Receptors, Erythropoietin|*Signal Transduction Pathways|JAK2 protein, human|Janus Kinase 2|*Epoetin Alfa|Phosphorylation|DNA-Binding Proteins|Trans-Activators|*Protein Binding|Interleukin-3|Erythroleukemia|Tumor Suppressor Proteins|Granulocyte-Macrophage Colony-Stimulating Factor | |
11010967 J. Biol. Chem. 2000 coactivator-associated arginine methyltransferase 1|*Receptors, Estrogen|*Protein Arginine Methyltransferase|NCOA2 protein, human|Glucocorticoid Receptor-Interacting Protein 1|G-T mismatch-binding protein|*DNA-Binding Proteins|EP300 protein, human|*E1A-Associated p300 Protein|NCOA1 protein, human|Steroid Receptor Coactivator 1|Activation, Transcriptional|*Estrogens|Nuclear Proteins|Trans-Activators|Binding Site|Histone Acetyltransferases|Promoter Regions, Genetic | |
11012668 Eur. J. Biochem. 2000 Humans|Rats|Animals|*Calcifediol|Escherichia coli|Adrenodoxin|Steroid Hydroxylases|Vitamin D3 24-Hydroxylase|Hydroxylation|Calcitriol|Vitamin D|Cytochrome P-450 Enzyme System|*Catalysis|Recombinant Proteins|Substrate Specificity|*Metabolic Pathway|Adrenodoxin Reductase|Kinetics|Mass Spectrometry|HPLC|cDNA | |
11012776 Immunology 2000 PMC2327072 Humans|Rabbits|Animals|ficolin|*Monocytes|*Acetylglucosamine|*Escherichia coli|*Glucosamine|U937 Cells|Escherichia coli K12|*Lectins|*Phagocytosis|Granulocytes|Carrier Proteins|Protein Binding|Fibrinogen|N-Acetylneuraminic Acid | |
11013134 Am. J. Hum. Genet. 2000 PMC1288551 Humans|Animals|2-methylacyl-CoA dehydrogenase|*Isoleucine|Oxidoreductases Acting on CH-CH Group Donors|Tiglic acidemia|*Amino Acid Metabolism, Inborn Errors|2-Methylbutyryl-CoA Dehydrogenase Deficiency|Acyl CoA Dehydrogenase|Exons|Oxidoreductases|Base Sequence|*Biochemical Phenomena|cDNA|Mutation|Valine | |
11013208 EMBO J. 2000 PMC302104 *Collagen Type XIII|*Membrane Proteins|Recombinant Proteins|Amino Acid Sequence|Protein Structure, Tertiary|Collagen|Plasma Membrane|Furin|Disulfides | |
11013220 EMBO J. 2000 PMC302105 *Transforming Growth Factor beta|SMAD3 protein, human|*Smad3 Protein|SMAD2 protein, human|*Smad2 Protein|SMAD4 protein, human|*Smad4 Protein|Signal Transduction|Trans-Activators|Cyclin-Dependent Kinase Inhibitor p15|Promoter Regions, Genetic|Transcription, Genetic|Cyclin-Dependent Kinase Inhibitor p21|Protein Binding|Cyclins|Cyclin-Dependent Kinase Inhibitor p16|Sp1 Transcription Factor | |
11014198 Nature 2000 Animals|*Active Transport, Cell Nucleus|*RNA, Messenger, Splicing|messenger ribonucleoprotein|Ribonucleoproteins|RNA Precursors|Messenger RNA|RNA Transport|RNA-Binding Proteins|Cell Nucleus|Nuclear Proteins|Introns|Transcription Factors|Exons|Cytoplasm | |
11015561 Physiol. Genomics 2000 Animals|Rats|Humans|*Alternative Splicing|*Glutaminase|Amino Acid Sequence|Base Sequence|Cloning, Molecular|mRNA|Sequence Alignment|DNA, Complementary|Genome|Sequence Homology, Amino Acid|Isoenzymes|Sequence Analysis, DNA | |
11015615 Physiol. Rev. 2000 Animals|*Phosphoinositide Phospholipase C|PLCB3 protein, human|*Phospholipase C beta|Phosphatidylinositols|Signal Transduction|1,2-diacylglycerol|Diglycerides|Phosphatidylinositol 4,5-Diphosphate|Second Messengers|glycerophosphoinositol glycerophosphodiesterase|*Phosphodiesterases|Phospholipase C delta1|Isoenzymes|*Phospholipase C gamma|Cell Membrane|Catalysis | |
11015619 Physiol. Rev. 2000 Animals|*Calcineurin|FK506|Cyclosporine A|Calcineurin Inhibitors|Immunosuppressive Agents|FK506 Binding Protein|Signal Transduction Pathways|Amino Acid Sequence|Binding Sites|Peptidylprolyl Isomerase|Carrier Proteins|Calmodulin-Binding Proteins|Calmodulin|Heat-Shock Proteins|Models, Molecular|Saccharomyces cerevisiae|Active Site | |
11016445 Diabetes 2000 Humans|Mice|Animals|fructosamine-3-kinase|*Phosphotransferases (Alcohol Group Acceptor)|Fructosamine|1-deoxyfructose|Fructose|1-deoxy-1-morpholinofructose|Phosphorylation|Amino Acid Sequence|Proteins|fructosyl-lysine|Lysine|Substrate Specificity|Glucose|Amino Acids|Erythrocyte|Escherichia coli|Morpholines|*Mammals | |
11016919 J. Biol. Chem. 2000 *Transforming Growth Factor beta|*Ubiquitin Ligase E3|*Proteasome Endopeptidase Complex|SMAD2 protein, human|*Smad2 Protein|SMAD3 protein, human|Smad3 Protein|*Signal Transduction|Ubiquitin|SMAD4 protein, human|Smad4 Protein|Trans-Activators|Ubiquitins|Cytoplasm|Protein Binding|Transforming Growth Factors | |
11016959 Proc. Natl. Acad. Sci. U.S.A. 2000 PMC17218 Humans|Mice|Animals|*Cytokine Receptor|IL2RG protein, human|Interleukin Receptor Common gamma Subunit|Leukocytes, Mononuclear|IL2RB protein, human|*Interleukin-2 Receptor beta Subunit|IL21R protein, human|Interleukin-21 Receptor alpha Subunit|Receptors, Interleukin|STAT5A protein, human|STAT5 Transcription Factor|Interleukin-2|Lymphocyte Activation|Signal Transduction|Amino Acid Sequence|Base Sequence|B Cells|Killer Cells, Natural | |
11017086 Nat. Genet. 2000 Humans|Macular dystrophy, corneal type 1|*Corneal Dystrophies, Hereditary|*Mutations|*Sulfotransferases|DNA Mutational Analysis|Pedigree|Cornea|Phenotypes|Polymerase Chain Reaction|Amino Acid Sequence|Keratan Sulfate | |
11017109 Nat. Immunol. 2001 DC-specific ICAM-3 grabbing nonintegrin|*Lectin, C-Type|*Receptors, Cell Surface|*Cell Adhesion Molecules|Antigens, CD|*Cell Movement|Dendritic Cells|Ligands | |
11017172 Nat. Neurosci. 2000 *GABA Plasma Membrane Transport Proteins|*Syntaxin 1|Nerve Tissue Proteins|Biological Transport|SNARE|Signal Transduction|Protein Binding|gamma-Aminobutyric Acid|Synaptic Transmission|Antigens, Surface|Organic Anion Transporters|Calcium Channels|Neurotransmitter|Chloride Channels | |
11017805 Am. J. Hum. Genet. 2000 PMC1288570 Male|Humans|Animals|*Hedgehogs|Anorchia|*Gonadal Dysgenesis, 46,XY|*Peripheral Nervous System Diseases|Exon|Homozygote|Polyneuropathy|Mutation|Endoneurium|*Testis|Nerve, Sural|Hedgehog Proteins|Missense Mutation | |
11018014 Genes Dev. 2000 PMC316979 Humans|Animals|*Drosophila|*I-kappa B Kinase|Drosophila Proteins|Transcription Factors|Drosophila melanogaster|Signal Transduction|Gene Expression Regulation|Phosphorylation|*Anti-Bacterial Agents | |
11018020 Genes Dev. 2000 PMC316978 *RNA, Transfer, Met|*EIF3|*EIF-2|EIF1 protein, human|*Eukaryotic Initiation Factors|Eukaryotic Initiation Factor-5|Saccharomyces cerevisiae|Ribosomes|Saccharomyces cerevisiae Proteins|Eukaryotic Initiation Factor-1|Start Codon|Peptide Chain Initiation, Translational|*Nerve Tissue Proteins|Protein Biosynthesis|*Neoplasm Proteins|Guanosine Triphosphate|Protein Subunits | |
11018023 J. Biol. Chem. 2000 Humans|Endothelial Cells|ARNTL2 protein, human|*ARNTL Transcription Factors|CLOCK Proteins|Gene Expression Regulation|Transcriptional Activation|Sites, E-Box|Promoter Regions, Genetic|Trans-Activators|Circadian Rhythm|Helix-Loop-Helix Motifs|Suprachiasmatic Nucleus|SERPINE1 protein, human|PAI-1|Clock, Biological|RNA, Messenger|Plasminogen | |
11018027 J. Biol. Chem. 2000 *Leucine Zippers|*Dimerization|*Activating Transcription Factor 4|CEBPB protein, human|*CCAAT-Enhancer-Binding Protein-beta|*DNA|bZIP Transcription Factors|Binding Sites|DNA Sequence|Amino Acid Sequence|Circular Dichroism|Electrophoretic Mobility Shift Assay|*Protein Domains | |
11018042 J. Biol. Chem. 2000 Chlorocebus aethiops|Animals|LIMK2 protein, human|LIMK1 protein, human|*Lim Kinases|*Phosphorylation|*Threonine|ROCK1 protein, human|*rho-Kinase|Protein Kinases|Actin|Actin Depolymerizing Factors|Cytoskeleton|Microfilament Proteins|PAK1 protein, human|p21-Activated Kinases|rho GTPases|COS Cells|Signal Transduction|DNA-Binding Proteins | |
11018043 J. Biol. Chem. 2000 *Catalytic Domain|(N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase|Disulfides|*N-Acetylgalactosaminyltransferases|Mutagenesis, Site-Directed|*Dimerization|Amino Acid Sequence|Cysteine|Binding Sites|Amino Acid Substitution|Mass Spectrometry|Thiols|*Protein Domains|*Orientation, Spatial | |
11018044 J. Biol. Chem. 2000 leptin receptor, human|*Receptors, Leptin|*Suppressor of Cytokine Signaling Proteins|STAT3 protein, human|STAT3 Transcription Factor|Signal Transduction|PTPN11 protein, human|Tyrosine Phosphatase, Shp-2|Leptin|Phosphorylation|Suppressor of Cytokine Signaling 3 Protein|Janus Kinase 2|Repressor Proteins|Erythropoietin Receptor|Receptors, Cell Surface|Mutation | |
11018045 J. Biol. Chem. 2000 Humans|*Metallochaperones|*Copper|*Superoxide Dismutase-1|*Molecular Chaperones|Superoxide Dismutase|Zinc|*Oxidation-Reduction|Dimerization|Amino Acid Sequence|Protein Structure, Tertiary|Saccharomyces cerevisiae|Protein Binding|Binding Sites|Fungal Proteins|Ions | |
11018049 J. Cell Biol. 2000 PMC2189805 Animals|*mRNA|*Ligands|exportin 1 protein|Karyopherins|Receptors, Cytoplasmic and Nuclear|ELAV Proteins|ELAV-Like Protein 1|Cytoplasm|Export, Nuclear|RNA Stability|Cell Nucleus|TYRP1 protein, human|*Membrane Glycoproteins|fos Gene|Antigens, Surface|3' Untranslated Regions|Protein Binding|AU Rich Elements | |
11018052 J. Cell Biol. 2000 PMC2189804 Mice|Animals|*Agrin|*Isoforms|Neuromuscular Junction|Receptors, Cholinergic|Receptor Aggregation|Proteoglycan|Neurons|Basal Lamina|Muscles|Central Nervous System | |
11018053 J. Cell Biol. 2000 PMC2189810 *Syndecan Binding Protein 2|SDC2 protein, human|*Syndecan-2|*Dendritic Spines|*Neurons|perlecan|Heparan Sulfate Proteoglycans|Nerve Tissue Proteins|Syndecan|Hippocampus|Membrane Proteins|Amino Acid Sequence|Synapses|Protein Binding | |
11018120 J. Physiol. (Lond.) 2000 PMC2270117 Humans|*AMP-Activated Protein Kinases|*Muscle, Skeletal|Glycogen|*Isoforms|Protein-Serine-Threonine Kinases|Exercise|Glucose|Multienzyme Complexes|Quadriceps Muscle | |
11018254 Biochim. Biophys. Acta 2000 Humans|NAB1 protein, human|*Repressor Proteins|EGR1 protein, human|Early Growth Response Protein 1|Zinc Finger Motifs|Binding Sites|Immediate-Early Proteins|Transcription, Genetic|Promoter Regions, Genetic|Transcriptional Activation|Gene Expression Regulation|Cell Differentiation|Cell Line | |
11018465 Biochim. Biophys. Acta 2000 Humans|sphingosine 1-phosphate lyase (aldolase)|*DNA, Complementary|In Situ Hybridization, Fluorescence|*Aldehyde-Lyases|sphingenine-1-phosphate|Sphingosine|Cloning, Molecular|Base Sequence|Amino Acid Sequence|*Chromosome Structures|mRNA|Sequence Homology, Amino Acid|Intracellular Second Messenger | |
11022047 J. Biol. Chem. 2000 *Phospholipase C|*Mitogen-Activated Protein Kinases|Heterotrimeric GTP-Binding Proteins|Signal Transduction|*Phospholipases A|Phosphoinositide Phospholipase C|Enzyme Activation|ras Proteins|Protein Binding|Monomeric GTP-Binding Proteins|Amino Acid Sequence|Second Messengers|Transfection|Inositol Phosphates | |
11022048 J. Biol. Chem. 2000 Animals|Chlorocebus aethiops|Humans|*Phospholipase C|RAP1A protein, human|rap1 GTP-Binding Proteins|Phosphoinositide Phospholipase C|RASGRF1 protein, human|ras-GRF1|Signal Transduction|ras Proteins|Inositol Phosphates|COS Cells|Protein Binding|HRAS protein, human | |
11023036 J. Gastroenterol. 2000 Humans|Rats|Animals|*Hepatocyte|bilirubin glucuronate|*Bilirubin|Canaliculi, Bile|Liver|multidrug resistance-associated protein 2|Multidrug Resistance-Associated Proteins|Organic Anion Transporters|Biological Transport|Bile|ATP-Binding Cassette Transporters|UGT1A1 enzyme|Glucuronosyltransferase|Transporters, Membrane|*Ion Transport | |
11024015 J. Biol. Chem. 2000 Humans|Animals|Rats|phenylalanyl-leucyl-phenylalanyl-glutaminyl-prolyl-glutaminyl-arginyl-phenylalaninamide|*Oligopeptides|*G-Protein-Coupled Receptors|Receptors, Neuropeptide|Protein Binding|Amino Acid Sequence|Spinal Cord|Central Nervous System|Sequence Homology, Amino Acid|Binding Sites|Brain|mRNA|Cloning, Molecular | |
11024028 J. Biol. Chem. 2000 Mice|Humans|Animals|*Ammonia|Phylogeny|HEK293 Cells|Glycoproteins|Biological Transport|Membrane Glycoproteins|*Mammals|Amino Acid Sequence|N-Glycanase|Cation Transport Proteins|Sequence Homology, Amino Acid|Plasma Membrane|Archaea|glycoprotein B, Simplexvirus|*Viral Envelope Proteins|Cloning, Molecular|Kidney|RHBG protein, human | |
11024047 J. Biol. Chem. 2000 *Transforming Growth Factor beta|*Activin|SMAD2 protein, human|Smad2 Protein|SMAD3 protein, human|Smad3 Protein|*Signal Transduction|Nodal Protein|Bone Morphogenetic Proteins|Activin Receptors, Type I|Trans-Activators|Homeodomain Proteins|Xenopus Proteins|Phosphorylation|Neoplasm Proteins|Activin Receptors, Type II|Epidermal Growth Factor|Transforming Growth Factors | |
11024059 J. Biol. Chem. 2000 VHL protein, human|*Von Hippel-Lindau Tumor Suppressor Protein|Renal Cell Carcinoma|*Exon|Transcription Factors|DNA-Binding Proteins|Nuclear Proteins|Kidney Neoplasms|von Hippel-Lindau Disease|Elongin|Ligases|Mutations|Genes, Tumor Suppressor|Genes, Regulator | |
11025670 Nat. Cell Biol. 2000 Animals|*Phosphorylation|*Threonine|ATM protein, human|ATM Protein|Ataxia-Telangiectasia|Tumor Suppressor Proteins|Cell Cycle Proteins|DNA Damage|S Phase|DNA-Binding Proteins|Protein Kinase|Checkpoint Kinase 2|G2 Phase|G1 Phase|Cell Cycle|M Phase|Nuclear Proteins|Tumor Suppressor Protein p53 | |
11027153 Biochemistry 2000 Humans|Animals|Mice|*Anticodon|pseudouridylate synthetase|*Hydro-Lyases|Pseudouridine|Nucleic Acid Conformation|Saccharomyces cerevisiae|Uridine|Substrate Specificity|Amino Acid Sequence|tRNA(Leu) | |
11027271 Mol. Cell. Biol. 2000 PMC86411 *Retinoid X Receptors|*Nuclear Receptor Coactivators|*PPAR gamma|G-T mismatch-binding protein|DNA-Binding Proteins|NCOA1 protein, human|Nuclear Receptor Coactivator 1|Receptors, Retinoic Acid|Nuclear Proteins|Trans-Activators|Histone Acetyltransferases|Transcriptional Activation|Carrier Proteins|Ligands|Transfection|Protein Binding|Dimerization|Amino Acid Sequence | |
11027307 Proc. Natl. Acad. Sci. U.S.A. 2000 PMC17291 Animals|*Hedgehog Proteins|Neural Stem Cells|Patched Receptors|PTCH protein, human|Patched-1 Receptor|Signal Transduction|Receptors, Cell Surface|Trans-Activators|Drosophila Proteins|Drosophila|Membrane Proteins|*Endocytosis|Intracellular Signaling Peptides and Proteins|Cell Lines|Sequence Homology, Amino Acid | |
11027551 Biochem. Biophys. Res. Commun. 2000 *Hematopoiesis|DNA-Binding Proteins|Transcription Factors|Helix-Loop-Helix Motifs|Cell Differentiation|*Gene Expression|Hematopoietic Stem Cells|Repressor Proteins|Inhibitor of Differentiation Protein 1|Embryonic Stem Cells|Hematopoietic Stem Cell Transplantation | |
11027560 Biochem. Biophys. Res. Commun. 2000 Humans|Rats|Animals|*Hemicholinium 3|choline transporter|*Membrane Transport Proteins|*Cloning, Molecular|cDNA|Choline|Biological Transport|Carrier Proteins|Acetylcholine|Amino Acid Sequence|Sodium|Blotting, Northern|Ion Transport|RNA, Messenger | |
11027599 Biochem. Biophys. Res. Commun. 2000 Male|Rabbits|Animals|Rats|*Epididymis|*Testis|*Spleen|aquaporin 8|*Aquaporins|AQP9 protein, human|*Liver|Hepatocytes|Microscopy, Immunoelectron|Immunohistochemistry|Blotting, Western|Leydig Cells|*Brain|Immunoblotting|RNA, Messenger|Aqp9 protein, rat | |
11027606 Biochem. Biophys. Res. Commun. 2000 Humans|Animals|heparanase|*Glucuronidase|cDNA|mRNA|Amino Acid Sequence|*Mammals|Alternative Splicing|Base Sequence|Cloning, Molecular|Gene Expression Profiling|Expressed Sequence Tags|Proteins|Tumor Cells, Cultured|Sequence Homology, Amino Acid | |
11027663 Biochem. Biophys. Res. Commun. 2000 *PI3-Kinase|flt3 ligand protein|*Phosphorylation|GAB1 protein, human|GAB2 protein, human|GRB2 protein, human|*GRB2 Adaptor Protein|*Membrane Proteins|PTPN11 protein, human|*Protein Tyrosine Phosphatase, Non-Receptor Type 11|SH2 Domain-Containing Protein Tyrosine Phosphatases|Signal Transduction|*Phosphatidylinositol 3-Kinase|Phosphoproteins|src Homology Domains|PIK3CG protein, human|*Class Ib Phosphatidylinositol 3-Kinase|Protein Tyrosine Phosphatase, Non-Receptor Type 6 | |
11029004 Nature 2000 Humans|Animals|Mice|Neuroglobin|*Vertebrate|*Brain|Nerve Tissue Proteins|Amino Acid Sequence|Hemoglobins|Exon|Sequence Homology, Amino Acid|Phylogeny|Intron|Cloning, Molecular | |
11029007 Nature 2000 Animals|*LDL-Receptor Related Proteins|CTNNB1 protein, human|beta Catenin|LDLR protein, human|Low Density Lipoprotein Receptor|Low Density Lipoprotein Receptor-Related Protein-6|Frizzled Proteins|Wnt Proteins|Wnt1 Protein|*Wnt Signaling Pathway|Protein Binding|Trans-Activators|Xenopus laevis|Drosophila|Membrane Proteins|Xenopus Proteins|Proto-Oncogene Proteins|Zebrafish Proteins | |
11029009 Nature 2000 PMC2670482 Animals|Mice|*Phosphatidylinositol-3-OH Kinase|*Receptors, Estrogen|AKT1 protein, human|Protein Kinase B|NOS3 protein, human|Endothelial Nitric Oxide Synthase|Signal Transduction|Estrogens|Phosphorylation|Nitric Oxide|Endothelium, Vascular|ERalpha | |
11029283 Am. J. Physiol., Cell Physiol. 2000 *Phosphofructokinase-2|*Glycolysis|*Fructose|Phosphoric Monoester Hydrolases|Fructosediphosphates|Phosphotransferases (Alcohol Group Acceptor)|Phosphorylation|Liver|Cell Cycle | |
11029403 Circ. Res. 2000 Humans|NOS3 protein, human|*Nitric Oxide Synthase Type III|GPER1 protein, human|*Receptors, Estrogen|*Phosphatidylinositol 3-Kinase|*Proto-Oncogene Proteins c-akt|*Endothelial Cells|Vascular Endothelial Growth Factor A|*Receptors, G-Protein-Coupled|Phosphorylation|Nitric Oxide Synthase|Phosphatidylinositol 3-Kinases|Signal Transduction|Enzyme Activation|Proto-Oncogene Proteins|Nitric Oxide|Endothelium, Vascular|2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one | |
11030334 Mol. Cell 2000 Humans|*NFATC Transcription Factors|DNA-Binding Proteins|Nuclear Proteins|Transcriptional Activation|Calcineurin|Binding Sites|Cell Nucleus|Phosphorylation|Amino Acid Sequence|Ionomycin|Nuclear Localization Signal|Tetradecanoylphorbol Acetate|*Molecular Conformation|Jurkat Cells|Signal Transduction|Transfection|Cell Line | |
11030628 Cell 2000 Humans|*Phosphorylation|*Tumor Suppressor Protein p53|*Apoptosis|Cyclin-Dependent Kinase Inhibitor p21|DNA Damage|Activation, Transcriptional|Nuclear Proteins|Cyclins|Protein Binding|Mitochondria|Cell Line, Tumor | |
11030716 Br. J. Pharmacol. 2000 PMC1572376 Animals|Humans|Rats|PRLH protein, human|*Prolactin-Releasing Hormone|Iodine-125|*Iodine Radioisotopes|HEK293 Cells|Kinetics|*Receptors, G-Protein-Coupled|Hypothalamic Hormones|Neuropeptides|Hypothalamus|phenylalanyl-leucyl-phenylalanyl-glutaminyl-prolyl-glutaminyl-arginyl-phenylalaninamide|Oligopeptides|Cyclic AMP | |
11030741 Glycobiology 2000 Mice|Animals|*Keratan Sulfate|link protein|Proteoglycan|Chondroitin Sulfate Proteoglycans|Extracellular Matrix Proteins|Lumican|Cornea|Sulfotransferases|Knockout Mouse | |
11031247 Annu. Rev. Cell Dev. Biol. 2000 PMC4781643 *Protein Transport|Golgi Apparatus|Endoplasmic Reticulum|TYRP1 protein, human|*Membrane Glycoproteins|Secretory Pathway|Green Fluorescent Proteins|Photobleaching|*Cell Movement | |
11031251 J. Biol. Chem. 2000 PMC3422575 Humans|Mice|Animals|*Phospholipases A2, Cytosolic|Cloning, Molecular|Recombinant Proteins|Amino Acid Sequence|Kinetics|Escherichia coli|*Biochemical Phenomena|Tissue Distribution|cDNA|Sequence Homology, Amino Acid|*Group IB Phospholipases A2|Phospholipids|sPLA(2)|Hydrogen-Ion Concentration | |
11032757 Mol. Cell Biol. Res. Commun. 2000 Humans|*Retinoblastoma Protein|CCND1 protein, human|*Cyclin D1|*Phosphorylation|*Down-Regulation|CDK4 protein, human|*Cyclin-Dependent Kinase 4|CDK2 protein, human|*Cyclin-Dependent Kinase 2|CCNE1 protein, human|Cyclin E|CDK6 protein, human|Cyclin-Dependent Kinase 6|CDC2-CDC28 Kinases|G1 Phase|Proto-Oncogene Proteins|Cell Cycle|Cyclin A | |
11032810 EMBO J. 2000 PMC314015 Rats|Mice|Chlorocebus aethiops|Animals|*Proto-Oncogene Proteins B-raf|*Phosphorylation|Proto-Oncogene Proteins c-raf|Mitogen-Activated Protein Kinases|Enzyme Activation|MAP Kinase Kinase 1|MAP Kinase Signaling System|Signal Transduction|Cell Transformation, Neoplastic|PC12 Cell|Serine|COS Cells|Cell Differentiation|3T3 Cells | |
11032836 J. Biol. Chem. 2000 Humans|*Porphobilinogen Synthase|Amino Acid Sequence|Binding Sites|Kinetics|Zinc|Magnesium|Catalysis|Escherichia coli|Lead Poisoning | |
11032837 J. Biol. Chem. 2000 Male|Mice|Humans|Animals|*Pyrimidine Nucleosides|cif nucleoside transporter|*Membrane Transport Proteins|sodium-nucleoside cotransporter|*Symporters|purine|Purine Nucleosides|Uridine|Amino Acid Sequence|Nucleosides|pyrimidine|Biological Transport|Sodium|Protein Structure, Secondary|Xenopus laevis|Kinetics|cDNA | |
11032841 J. Biol. Chem. 2000 Animals|Humans|*Porphobilinogen Synthase|*Catalytic Domain|*Lysine|Escherichia coli|Binding Sites|Catalysis|Amino Acid Sequence|Kinetics|Aminolevulinic Acid|Porphobilinogen|Models, Molecular|Schiff Base|*Mutations|Magnesium|5-amino levulinic acid|Levulinic Acids|Zinc | |
11034064 Cancer Res. 2000 Humans|Breast Cancer, Familial|*Breast Neoplasms|In Situ Hybridization, Fluorescence|Comparative Genomic Hybridization|*Genes, myb|BRCA1 protein, human|*BRCA1 Protein|Genes, BRCA2|Genes, BRCA1|BRCA2 protein, human|BRCA2 Protein|Gene Amplification|*Oncogene|Heterozygote|DNA, Neoplasm|MYBL2 protein, human|*Cell Cycle Proteins|Gene Expression Profiling | |
11034202 Nature 2000 Humans|*Aquaporin 1|*Water|Protein Conformation|Protons|Models, Molecular|Lipid Bilayers|Crystallography, X-Ray|Membrane Channel|Amino Acid Sequence|Biological Transport|Hydrophobic and Hydrophilic Interactions|Computer Simulation|Permeability | |
11034341 FEBS Lett. 2000 *Pentose Phosphate Pathway|*Phosphofructokinase-2|*Fructose|Fructosediphosphates|Glycolysis|Phosphoric Monoester Hydrolases|*Biochemical Phenomena|*Oxidative Stress|Kinetics|NADPH|Liver|*B Cells | |
11034610 J. Exp. Med. 2000 PMC2195872 Humans|Mice|Animals|*Cyclooxygenase 2|*Omega-3 Fatty Acids|Endothelial Cells|*Anti-Inflammatory Agents, Non-Steroidal|Aspirin|*Eicosanoids|*Anti-Inflammatory Agents|Lipoxins|Indometacin|Inflammation|Polymorphonuclear Leukocytes|Hydroxyeicosatetraenoic Acids | |
11035026 J. Biol. Chem. 2000 Animals|*Golgi Apparatus|*Endoplasmic Reticulum|Syntaxin 5|SNAP Receptor|Qc-SNARE Proteins|Qb-SNARE Proteins|Vesicular Transport Proteins|R-SNARE Proteins|*Mammals|Membrane Fusion|Biological Transport|Endosomes | |
11035028 J. Biol. Chem. 2000 IRF3 protein, human|*Interferon Regulatory Factor-3|*Phosphorylation|*Signal Transduction|Activation, Transcriptional|viral interferon regulatory factors|Interferon Regulatory Factors|Trans-Activators|Cell Nucleus|Cytoplasm|Protein Processing, Post-Translational|Protein Binding|Promoter Regions, Genetic|Viral Proteins|RNA, Double-Stranded | |
11035033 J. Biol. Chem. 2000 macrogolgin|*Golgi Complex|*Golgi Matrix Proteins|*Endoplasmic Reticulum|Vesicular Transport Proteins|Membrane Proteins|Carrier Proteins|mannosyl-oligosaccharide 1,3 - 1,6-alpha-mannosidase|Mannosidases|Biological Transport|Autoantigens|Protein Binding|G Protein|Vesicular stomatitis Indiana virus | |
11035045 J. Biol. Chem. 2000 *Casein Kinase II|PTEN protein, human|*PTEN Phosphohydrolase|*Phosphorylation|*Proteasome Endopeptidase Complex|*Genes, Tumor Suppressor|CSNK2A1 protein, human|Proto-Oncogene Proteins c-akt|Signal Transduction|Amino Acid Sequence|Cysteine Endopeptidases | |
11035113 J. Immunol. 2000 PROCR protein, human|*Endothelial Protein C Receptor|*Proteinase 3|*Neutrophils|*Macrophage-1 Antigen|*Neutrophil Activations|drotrecogin alfa activated|Protein C|Receptors, Cell Surface|Cell Adhesion|Blood Coagulation|Integrins|Anticoagulant|Endothelium, Vascular | |
11035788 Proc. Natl. Acad. Sci. U.S.A. 2000 PMC17280 *RNase H|reverse transcriptase, Human immunodeficiency virus 1|*HIV Reverse Transcriptase|*RNAse H, HIV|Templates, Genetic|Nucleic Acid Conformation|Base Sequence|DNA|RNA, Viral|Substrate Specificity|Viral Genome | |
11035813 Proc. Natl. Acad. Sci. U.S.A. 2000 PMC18785 plexin|CD100 antigen|*Semaphorin|Nerve Tissue Proteins|Antigens, CD|*Ligands|Receptors, Cell Surface|RHOA protein, human|rhoA GTP-Binding Protein|Signal Transduction|Growth Cones|Membrane Glycoproteins|Rho Guanine Nucleotide Exchange Factors|Cell Movement|Cytoskeleton | |
11036064 J. Biol. Chem. 2000 Humans|*Mint|Munc18 Proteins|Carrier Proteins|Exocytosis|Vesicular Transport Proteins|Nerve Tissue Proteins|Syntaxin 1|Synaptic Vesicles|Adaptor Proteins, Signal Transducing|Plasma Membrane|Synaptic Transmission|Neurons|Membrane Fusion|Protein Binding|Cadherins|Biological Transport | |
11038176 J. Cell Biol. 2000 PMC2192651 transport protein particle, TRAPP|*Vesicular Transport Proteins|Golgi Apparatus|Saccharomyces cerevisiae Proteins|*Guanine Nucleotides|Saccharomyces cerevisiae|rab GTP-Binding Proteins|Protein Transport|Endoplasmic Reticulum|Membrane Proteins|Guanine Nucleotide Exchange Factors|Protein Binding|Biological Transport|YPT1 protein, S cerevisiae | |
11038187 J. Cell Biol. 2000 PMC2192659 *Membrane Fusion|*HIV-1|HIV Envelope Protein gp41|*HIV Antibodies|HIV Fusion Inhibitors|CD4 Antigens|Protein Conformation|Kinetics|Peptides|Cell Line|Cell Membranes | |
11038283 Anal. Biochem. 2000 Humans|*Genes, ras|Endopeptidases|Amino Acid Sequence|F-chemotactic peptide|Oligopeptides|Protein Prenylation|Substrate Specificity|rasagiline|*Indans|Proteins|Protease Inhibitors|Kinetics|Amino Acids | |
11040182 Gastroenterology 2000 Humans|*Lipolysis|gastric lipase, human|*Lipase|*Digestion|Pancreatic Juice|Gastric Juice|Pancreas|Triglycerides|*Meals | |
11041856 Biochemistry 2000 Animals|Chlorocebus aethiops|Humans|nucleoside-diphosphatase|Endothelial Cells|*Acid Anhydride Hydrolases|Apyrase|Adenosine Triphosphatases|Adenosine Diphosphate|COS-7 Cells|Transfections|Antigens, CD|*Heart|Hydrolysis|Platelet Activation|Recombinant Proteins|Glycosylation | |
11041857 Biochemistry 2000 Animals|Humans|Chlorocebus aethiops|Apyrase|ENTPD5 protein, human|Pyrophosphatases|Adenosine Triphosphatases|COS-7 Cells|Transfections|Recombinant Proteins|Substrate Specificity|Glycosylation|Amino Acid Sequence|Antigens, CD|Kinetics|Molecular Weight|Oncogene Proteins | |
11042108 Biochem. J. 2000 PMC1221393 Humans|Inositol Phosphates|*Signal Transduction|Phosphotransferases (Alcohol Group Acceptor)|Phosphorylation|Cloning, Molecular|Recombinant Proteins|Kinetics|Amino Acid Sequence|Substrate Specificity|Sequence Homology, Amino Acid|cDNA | |
11042164 J. Biol. Chem. 2000 Mice|Animals|Phosphatidylinositol 3-Kinases|*Proto-Oncogene Proteins c-akt|*Antigens, CD19|*B-Lymphocytes|Receptors, Antigen, B-Cell|Phosphorylation|Signal Transduction|*Adaptor Proteins, Signal Transducing|Proto-Oncogene Proteins c-vav|Enzyme Activation|Lymphoma, B-Cell | |
11042166 J. Biol. Chem. 2000 Humans|Pregnancy|Female|beta--1,3-N-acetylglucosaminyltransferase T4|beta-1,3-N--acetylglucosaminyltransferase T3|*N-Acetylglucosaminyltransferases|N-acetyllactosaminide alpha-1,3-galactosyltransferase|*Galactosyltransferases|poly-N-acetyllactosamine|Polysaccharides|Amino Acid Sequence|Oligosaccharides|Substrate Specificity|cDNA|Cloning, Molecular|Sequence Homology, Amino Acid|RNA, Messenger|Cell Line | |
11042191 J. Biol. Chem. 2000 Humans|*Phosphorylation|*Protein Kinase C|*Calmodulin|beta-Adrenergic Receptor Kinases|Cyclic AMP-Dependent Protein Kinases|Serine|G-Protein-Coupled Receptor Kinase 5|Receptors, Adrenergic, beta-2|Protein Binding|Amino Acid Sequence|Cell Line|Phorbol Esters | |
11042394 Biochim. Biophys. Acta 2000 Chlorocebus aethiops|Animals|Humans|Mice|N-acetyllactosamine|*Acetylglucosamine|*Amino Sugars|*Sulfotransferases|*Sulfates|Amino Acid Sequence|cDNA|Cloning, Molecular|COS-1 Cells|*Sulfur Oxides|Exons|Open Reading Frames|Genomics | |
11043579 Mol. Endocrinol. 2000 Humans|*Heparin-binding EGF-like Growth Factor|*Trans-Activators|MAPK3 protein, human|*Mitogen-Activated Protein Kinase 3|MAPK1 protein, human|*Mitogen-Activated Protein Kinase 1|EGFR protein, human|*Epidermal Growth Factor Receptor|*Receptors, G-Protein-Coupled|Estrogen Receptors|ICI 182,780|*MAP Kinase Signaling System|estrogen receptor alpha, human|Estrogen Receptor alpha|Signal Transduction|Oestradiol|Mitogen-Activated Protein Kinases|Estrogens | |
11044445 J. Biol. Chem. 2000 Rats|Humans|Animals|Cricetinae|NOS3 protein, human|*Endothelial Nitric Oxide Synthase|*Proto-Oncogene Proteins c-akt|*Endothelial Cells|Phosphatidylinositol 3-Kinases|CHO Cells|Cricetulus|*Estrogens|Phosphorylation|Nitric Oxide Synthase|Endothelium, Vascular|Estradiol|estrogen receptor alpha, human|Estrogen Receptor alpha|Proto-Oncogene Proteins|Enzyme Activation|ICI 182,780|Nitric Oxide | |
11044454 J. Biol. Chem. 2000 Cricetinae|Humans|Animals|ethanolamine kinase|CHKA protein, human|*Choline Kinase|CDP ethanolamine|*Cytidine Diphosphate|glycerophosphoethanolamine|Phosphatidylethanolamines|*Phosphotransferases (Alcohol Group Acceptor)|*Ethanolamines|phosphatidylethanolamine|Serine, Phosphatidyl|Ethanolamine|Phospholipids|*Mammals|Amino Acid Sequence|CHO Cells | |
11044475 Pediatr. Res. 2000 Humans|*Fanconi Syndrome|*DNA Mutational Analysis|SLC2A2 protein, human|*Glucose Transporter Type 2|Mutation|Renal Glucosuria|Homozygote|Glycogen Storage Disease|Mutation, Nonsense|Mutations, Missense|Heterozygotes|Monosaccharide Transport Proteins|Kidney Diseases|Liver | |
11044625 Mech. Dev. 2000 Humans|Mice|Animals|Somites|Notch Receptors|Mesoderm|Transcription Factors|Membrane Proteins|Intracellular Signaling Peptides and Proteins|Body Patterning|Basic Helix-Loop-Helix Transcription Factors|Receptor, Notch1|Signal Transduction|Gene Expression Regulation, Developmental|NOTCH3 protein, human|Receptor, Notch3|Cell Differentiation|HEYL protein, human|Repressor Proteins | |
11045624 Protein Sci. 2000 PMC2144698 Animals|*Peptide Elongation Factor Tu|*Guanine Nucleotides|elongation factor Ts|tRNA, Amino Acyl|EEF1A1 protein, human|*Peptide Elongation Factor 1|Guanosine Diphosphate|Guanosine Triphosphate|Ribosome|*Mitochondria|Escherichia coli|Kinetics|*Mammals | |
1104615 J. Biol. Chem. 1975 Kinetics|*Initiation Factor|Peptide Chain Initiation, Translational|Ribosomes|RNA, Transfer|Guanosine Triphosphate|Protein Binding|Methionine|Reticulocytes|*Biophysical Phenomena | |
11046155 Mol. Cell. Biol. 2000 PMC102165 Animals|Humans|ORC2 protein, human|*Origin Recognition Complex|*Chromatin|*Cell Cycle|*Mitosis|*Minichromosome Maintenance Proteins|*Cell Nucleus|DNA Replication|Cell Cycle Proteins|Minichromosome Maintenance Complex Component 4|Cyclin-Dependent Kinases|Cyclin B|Saccharomyces cerevisiae Proteins|Minichromosome Maintenance Complex Component 7|Minichromosome Maintenance Complex Component 6|Xenopus Proteins|Xenopus laevis|Phosphorylation | |
11048639 Exp. Mol. Med. 2000 *Phospholipase C gamma1|Phosphorylation|Protein Kinase C|1,2-diacylglycerol|Diglycerides|Enzyme Activation|Signal Transduction|Isoenzymes|Second Messengers|Phosphatidylinositol|Tyrosine|glycerophosphoinositol glycerophosphodiesterase|*Phosphoric Diester Hydrolases|Calcium | |
11050151 Proc. Natl. Acad. Sci. U.S.A. 2000 PMC18812 Humans|Rats|Animals|CTNNB1 protein, human|*beta Catenin|*Transcription Factors|Lymphoid Enhancer Factors|DNA-Binding Proteins|Trans-Activators|EP300 protein, human|*E1A-Associated p300 Protein|Lymphoid Enhancer-Binding Factor 1|Transcription, Genetic|CDH1 protein, human|E Cadherin|Nuclear Proteins|Wnt Proteins|Signal Transduction|Gene Expression Regulation|Cell Transformation, Neoplastic|Zebrafish Proteins | |
11053295 Invest. Ophthalmol. Vis. Sci. 2000 Humans|Fundus Albipunctatus|*Cone Dystrophy|Night Blindness|*Mutations|Electroretinography|DNA Mutational Analysis|*Retinal Dystrophies|Retinal Cone Photoreceptor Cells|Fluorescein Angiography|Pedigree|Visual Acuity|Alcohol Oxidoreductases|Polymerase Chain Reaction | |
11053425 J. Biol. Chem. 2000 Animals|*NF-kappa B|*Caspase Activation and Recruitment Domain|BCL10 protein, human|*B-Cell CLL-Lymphoma 10 Protein|CARD Signaling Adaptor Proteins|Signal Transduction|Adaptor Proteins, Signal Transducing|Caspases|Amino Acid Sequence|Neoplasm Proteins|RELA protein, human|Transcription Factor RelA|Lymphoma, B-Cell, Marginal Zone|Cell Line | |
11053437 J. Biol. Chem. 2000 Humans|Animals|SPRY2 protein, human|Membrane Proteins|Intracellular Signaling Peptides and Proteins|EGFR protein, human|Receptors, Epidermal Growth Factor|Proto-Oncogene Proteins c-cbl|Receptor Protein-Tyrosine Kinases|Proto-Oncogene Proteins|Ubiquitin-Protein Ligases|Nerve Tissue Proteins|Signal Transduction|Protein Binding|Phosphorylation|Amino Acid Sequence|Drosophila|MAP Kinase Signaling System|Cbl protein, Drosophila|Drosophila Proteins | |
11053835 Acta Crystallogr. D Biol. Crystallogr. 2000 Humans|Mice|Animals|fasciculin|*Acetylcholinesterase|*Elapid Venoms|Cholinesterase Inhibitors|Protein Conformation|Torpedo|*Snake Bites|Amino Acid Sequence|Protein Binding|Models, Molecular|Mutagenesis, Site-Directed|Snakes | |
11054122 Eur. J. Biochem. 2000 *Protein Disulfide-Isomerases|*Dimerization|Molecular Chaperones|Escherichia coli Proteins|Escherichia coli|HSP40 Heat-Shock Proteins|Chaperonin 10|Heat-Shock Proteins|HSP70 Heat-Shock Proteins|Protein Folding|Chaperonin 60|Bacterial Proteins|Inclusion Bodies|*Interleukin 12 | |
11054413 J. Biol. Chem. 2000 Humans|Proteins, BCL2 Family|bcl-X(L) Protein|Apoptosis|Alternative Splicing|Exons|Amino Acid Sequence|mRNA|Cell Death|HeLa Cells|Sequence Alignment|Cloning, Molecular|Protein Binding|Sequence Homology, Amino Acid|Transfection | |
11054547 Gene 2000 Animals|Humans|Mice|serine racemase|*Racemases and Epimerases|Serine|Amino Acid Sequence|*Genomics|Blotting, Northern|Aspartate|Astrocytes|Exons|Sequence Homology, Amino Acid|Pyridoxal Phosphate|Brain|Intron|Schizophrenia|Cloning, Molecular | |
11054877 Microsc. Res. Tech. 2000 Animals|*Laminin|Receptors, Laminin|Cell Adhesion|Integrin alpha6beta4|Membranes, Basement|Extracellular Matrix|Protein Binding|Cell Migration|Cell Polarity|Antigens, Surface|Cell Differentiation | |
11055896 Am. J. Hum. Genet. 2000 PMC1287918 Humans|*Mutation, Missense|Thanatophoric dysplasia, type 2|Thanatophoric Dysplasia|Thanatophoric Dysplasia, Type I|*Fibroblast Growth Factor Receptor 3|FGFR3 protein, human|Achondroplasia|*Osteochondrodysplasias|*Kinase|*Codon|*Phenotype|Substitutions, Amino Acid|Acanthosis Nigricans|*Musculoskeletal Abnormalities|Mutations|Hypochondroplasia|Skull|Lordosis | |
11056019 J. Cell. Physiol. 2000 Humans|*DNA Glycosylase|*Catalytic Domain|DNA Repair|Thymine DNA Glycosylase|Base Pair Mismatch|Endodeoxyribonucleases|Substrate Specificity|Thymine|5 Methylcytosine|Mutagenesis|Uracil|Guanine|DNA|MBD4 protein, human|MED1 protein, human|Mediator Complex Subunit 1 | |
11056176 J. Biol. Chem. 2000 Humans|*Small Nuclear RNA|RNA Polymerase II|TATA-Binding Protein|Transcription Factors|RNA Polymerase III|DNA-Binding Proteins|*Cell Nucleus|TATA Box|Transcription, Genetic|Promoter Regions, Genetic|Amino Acid Sequence|Protein Binding|POU2F1 protein, human|Octamer Transcription Factor-1 | |
11056388 J. Biochem. 2000 Adult|Chlorocebus aethiops|Humans|Mice|Rats|Animals|carbohydrate sulfotransferases|chondroitin 4-sulfotransferase|In Situ Hybridization, Fluorescence|*Sulfotransferases|*Cloning, Molecular|*Chromosome Mapping|cDNA|cDNA Library|Base Sequence|Amino Acid Sequence|Phosphoadenosine Phosphosulfate|Sequence Alignment|Sequence Homology, Amino Acid|Blotting, Northern|Chondroitin|COS-7 Cells|Open Reading Frame|Transfections | |
11057907 Cell 2000 *Polyubiquitin|CHUK protein, human|*I-kappa B Kinase|Tifab protein, human|*TNF Receptor-Associated Factor 6|UBE2N protein, human|*Ubiquitin-Conjugating Enzymes|Ubiquitin|MAP Kinase Kinase Kinases|NF-kappa B|Ubiquitin-Protein Ligases|Transductions, Signal|Adaptor Proteins, Signal Transducing|*Cytosol|Phosphorylation|Proteasome | |
11058110 Nucleic Acids Res. 2000 PMC113145 Humans|POLK protein, human|*DNA Polymerases|DNA Damage|Pyrimidine Dimers|DNA|8-hydroxyguanine|Guanine|DNA Adducts|Nucleotides|Templates, Genetic|Mutagenesis|Acetylaminofluorene|Benzo(a)pyrene | |
11058112 Nucleic Acids Res. 2000 PMC113156 Animals|Chick Embryo|Humans|*5-Methylcytosine|MBD4 protein, human|*Endodeoxyribonucleases|DNA Glycosylase|DNA|RNA|Substrate Specificity|Amino Acid Sequence|Oligonucleotides|Chicken|DNA Methylation|Recombinant Proteins | |
11058569 Int. Immunol. 2000 Humans|*Receptor, IL-13|interleukin-13, human|*Interleukin-13|*Interleukin-4|*Tyrosine|STAT3 protein, human|*STAT3 Transcription Factor|STAT6 protein, human|STAT6 Transcription Factor|JAK1 protein, human|Janus Kinase 1|Receptors, Interleukin-4|Interleukin-13 Receptor alpha1 Subunit|TYK2 Kinase|Signal Transduction|Janus Kinase 2|Receptors, Interleukin|Trans-Activators | |
11058585 J. Biol. Chem. 2000 p190RhoGEF protein, human|RHOA protein, human|*rhoA GTP-Binding Protein|RASGRF1 protein, human|*ras-GRF1|cdc42 GTP-Binding Protein|*Microtubules|platelet protein P47|Phosphoproteins|Rho Guanine Nucleotide Exchange Factors|rac1 GTP-Binding Protein|Signal Transduction|rho GTPases|Protein Binding|Stress Fibers|F-Actin|Blood Proteins|Amino Acid Sequence | |
11058897 Hum. Mutat. 2000 Humans|Cricetinae|Animals|Systemic carnitine deficiency|Cricetulus|SLC22A5 protein, human|Solute Carrier Family 22 Member 5|*Carnitine|*Cardiomyopathy|*Hyperammonemia|*Muscular Diseases|*Mutations|Organic Cation Transport Proteins|DNA Mutational Analysis|Membrane Proteins|Mutations, Missense|*Genotype-Phenotype Correlation|Biological Transport|Amino Acid Sequence|CHO Cells|cDNA | |
11060282 J. Biol. Chem. 2000 Humans|Mice|Animals|oxidized low density lipoprotein|*Chemokine CXCL16|acetyl-LDL|*Lipoproteins, LDL|*Macrophages|Scavenger Receptors, Class A|CD36 Antigens|Foam Cell|Scavenger Receptors, Class B|Receptors, Immunologic|Receptors, Oxidized LDL|*Cloning, Molecular|Cholesterol Esters|Endocytosis|cDNA|Serine, Phosphatidyl | |
11060341 J. Lipid Res. 2000 Mice|Animals|*Chylomicron Remnants|*Mice, Inbred C57BL|LDLR protein, human|LDL Receptor|*Apolipoproteins E|Chylomicrons|Apolipoproteins B|Apolipoproteins|Low Density Lipoprotein Receptor-Related Protein-1|*Liver|Mice, Knockout | |
11060344 J. Lipid Res. 2000 Cricetinae|Animals|Humans|alpha-methylacyl-CoA racemase|CHO Cells|Cricetulus|Peroxisomes|*Racemases and Epimerases|Peroxisome-Targeting Signal 1 Receptor|*Mitochondria|Green Fluorescent Proteins|Amino Acid Sequence|Receptors, Cytoplasmic and Nuclear|Transfection|Cloning, Molecular|Targeting Signal, Peroxisomal|cDNA|Bile Acids and Salts|Liver | |
11060359 J. Lipid Res. 2000 Rats|Humans|Animals|alpha-methylacyl-CoA racemase|Alpha-Methylacyl-CoA Racemase Deficiency|*Racemases and Epimerases|Peroxisomes|pristanic acid|Fatty Acids|Oxidation-Reduction|Bile Acids and Salts|Fatty Acyl CoA|Liver|Lipid Metabolism, Inborn Errors | |
11060443 Cytogenet. Cell Genet. 2000 Humans|prosecretin|*Secretin|*mRNA|Exons|Base Sequence|Amino Acid Sequence|*Gastrointestinal Hormones|Introns|Regions, Protein Coding|Cloning, Molecular|Blotting, Northern|*Protein Precursors|*Chromosome Structures|Sequence Alignment|DNA|In Situ Hybridization, Fluorescence | |
11062056 Biochem. J. 2000 PMC1221430 Adult|Animals|Humans|Rats|Mice|neolactotetraosylceramide alpha-2,3-sialyltransferase|Neu5Ac N-acetylgalactosamine 2,6-sialyltransferase|N-acetyllactosaminide alpha-2,3-sialyltransferase|*Sialyltransferases|Amino Acid Sequence|Cloning, Molecular|cDNA|Base Sequence|PCR|Substrate Specificity|Open Reading Frame|Sequence Homology, Amino Acid|Cell Line|*Chromosome Structures|Transfection | |
11062235 J. Biol. Chem. 2000 Rad50 protein, human|*DNA-Binding Proteins|*DNA Repair Enzymes|DNA Repair|Nuclear Proteins|DNA Damage|*Cell Nucleus|Cell Cycle Proteins|Nijmegen Breakage Syndrome|Cell Cycle|Amino Acid Sequence|BRCA1 protein, human|BRCA1 Protein|Protein Structure, Tertiary|Fungal Proteins|Protein Binding | |
11062261 J. Cell Biol. 2000 PMC2185588 Animals|*Endosomes|early endosome antigen 1|Vesicular Transport Proteins|rab5 GTP-Binding Proteins|phosphatidylinositol 3-phosphate|Phosphatidylinositol Phosphates|Membrane Fusion|Endocytosis|Membrane Proteins|GTPase|Intracellular Membranes|Amino Acid Sequence|Cytosol|Protein Binding | |
11062458 Nat. Genet. 2000 *Magnesium|*Sodium-Potassium-Exchanging ATPase|Hypomagnesemia primary|*Renal Tubular Transport, Inborn Errors|Hypomagnesemia 2, renal|Nephrocalcinosis|Hypercalciuria|Sodium|Amino Acid Sequence|Kidney|Cell Line|Kinetics|Mutation | |
11062476 Nat. Genet. 2000 Animals|Humans|*Saccharomyces cerevisiae|RHAG protein, human|*Membrane Glycoproteins|*Blood Proteins|*Ion Transport|*Yeast, Dried|Biological Transport|Glycoprotein|Rh Deficiency Syndrome|Rh-Hr Blood-Group System|methylamine|Methylamines|Cation Transport Proteins|*Kidney|*Macaca mulatta|Quaternary Ammonium Compounds|Ammonia|Erythrocytes | |
11062501 Nat. Immunol. 2001 *Class I Major Histocompatibility Molecules|tripeptide aminopeptidase|*Dipeptidyl-Peptidases and Tripeptidyl-Peptidases|enkephalin degrading enzyme|*Aminopeptidases|bleomycin hydrolase|*Cysteine Endopeptidases|endopeptidase B|Antigen Presentation|Proteasome|vesicular stomatitis virus nucleoprotein (52-59)|Nucleoproteins|T-Lymphocytes, Cytotoxic|Peptides|T-Cell Epitope|Peptide Fragments|Amino Acid Sequence | |
11063737 J. Biol. Chem. 2000 Humans|*Saccharomyces cerevisiae|*Sterols|Saccharomyces cerevisiae Proteins|*Yeast, Dried|*Mutations|Genes, Fungal|*Cytoplasm|Membrane Proteins|Plasma Membrane|Biological Transport|Esterification|Protein Transport|Lipid Metabolism|Cholesterol|ARV1 protein, human|Carrier Proteins|ARV1 protein, S cerevisiae | |
11063744 J. Biol. Chem. 2000 Mice|Rats|Animals|*Insulin Receptor Substrate Proteins|*Phosphorylation|*Insulin|*Phosphatidylinositol 3-Kinase|Glycogen Synthase Kinase 3|protein kinase C zeta|*Protein Kinase C|*Insulin, Regular, Human|Receptor, Insulin|Signal Transduction|protein kinase C kinase|Phosphoproteins|Phosphatidylinositol 3-Kinases|Serine|Substrate Specificity|NIH 3T3 Cells|Tyrosine | |
11063749 J. Biol. Chem. 2000 Animals|*Leucine|*Cysteine|Trans-Activators|Nuclear Proteins|HIF1A protein, human|*Hypoxia-Inducible Factor 1, alpha Subunit|EP300 protein, human|*E1A-Associated p300 Protein|Transcriptional Activation|Amino Acid Sequence|Protein Binding|Cell Hypoxia|Hypoxia | |
11063929 Curr. Opin. Cell Biol. 2000 *Cyclin B1|*Protein Kinase, Cdk1|*Mitosis|Cell Nucleus|cdc25 Phosphatases|Prophase|Phosphorylation|Protein-Serine-Threonine Kinases|Protein Kinases|DNA Damage|Nuclear Import | |
11067851 J. Biol. Chem. 2000 Humans|thrombospondin-1, human|*Thrombospondin 1|*Glycosylation|*Thrombospondin|Fucose|Mannose|Amino Acid Sequence|Mass Spectrometry|Protein Processing, Post-Translational|Tryptophan | |
11067870 J. Clin. Invest. 2000 PMC301421 Humans|Animals|Mice|*Genes, Synthetic|*Bile Acids|*Cholestasis|*Steroids|Liver|3-Hydroxysteroid Dehydrogenases|Exons|Mutation|Lipid Metabolism|DNA|mRNA|cDNA|Cholestasis, Intrahepatic | |
11068039 FEBS Lett. 2000 Humans|choline transporter|*Membrane Transport Proteins|Hemicholinium 3|Biological Transport|Carrier Proteins|Choline|Cloning, Molecular|Amino Acid Sequence|DNA, Complementary|Blotting, Northern|RNA, Messenger|Sequence Homology, Amino Acid | |
11069618 J. Invest. Dermatol. 2000 Humans|*DNA, Complementary|*Base Sequence|PADI3 protein, human|*Protein-Arginine Deiminase Type 3|*Cloning, Molecular|Epidermis|*Skin|Peptidylarginine Deiminase|trichohyalin|Intermediate Filament Proteins|Hair Follicle|Amino Acid Sequence|Keratinocytes|filaggrin|Hydrolases|Epidermal Cells|Isoenzymes|Protein-Arginine Deiminase Type 4 | |
11069780 J. Cell. Sci. 2000 Humans|BIRC5 protein, human|*Survivin|*Proteasome Endopeptidase Complex|*Cell Cycle|*M Phase|Apoptosis|Inhibitor Of Apoptosis Protein|Ubiquitins|G1 Phase|Proteasome Inhibitors|Cysteine Endopeptidases | |
11069885 Genes Dev. 2000 PMC317036 Animals|*Drosophila|*Rapamycin|Drosophila Proteins|Phosphatidylinositol 3-Kinases|TOR Serine-Threonine Kinases|Signal Transduction|Drosophila melanogaster|Ribosomal Protein S6 Kinases|Phosphotransferases (Alcohol Group Acceptor)|Saccharomyces cerevisiae Proteins|Cell Division|Tumor Suppressor Proteins | |
11069889 Genes Dev. 2000 PMC317029 Animals|*mRNA|*Unfolded Protein Response|ERN1 protein, human|Endoribonucleases|Protein-Serine-Threonine Kinases|Saccharomyces cerevisiae|Saccharomyces cerevisiae Proteins|Endoplasmic Reticulum|Signal Transduction Pathway|Protein Folding|Protein Kinase|*Autoregulation|Transcription Factors|*RNA 3' End Processing|Basic-Leucine Zipper Transcription Factors|Phosphorylation|Cell Nucleus|Amino Acid Sequence | |
11070003 J. Virol. 2000 PMC113188 Animals|Humans|*Lentivirus|nef Gene Products, Human Immunodeficiency Virus|PAK1 protein, human|p21-Activated Kinases|Human Immunodeficiency Virus Type 1|Simian Immunodeficiency Virus|Cell Lines|Alleles|PAK2 protein, human|nef protein, Human immunodeficiency virus 2|nef protein, Human immunodeficiency virus 1 | |
11071853 Biochem. Biophys. Res. Commun. 2000 PMC2924611 *Guanine Nucleotide Exchange Factors|Protein Kinase A|Glucagon-Like Peptide 1|8-chloro-cyclic adenosine monophosphate|*8-Bromo Cyclic Adenosine Monophosphate|Glucagon|Cyclic AMP|Insulin Secretion|Insulin|*Pancreatic beta Cells|Islets of Langerhans|Signal Transduction|Protein Precursors|Glucose | |
11071869 Biochem. Biophys. Res. Commun. 2000 Chlorocebus aethiops|Animals|B cell linker protein|GRB2 protein, human|GRB2 Adaptor Protein|SH3 Domains|Signal Transduction|Crk-Associated Substrate Protein|Protein Binding|Retinoblastoma-Like Protein p130|COS Cells|Transfection|SOS1 Protein | |
11071885 J. Biol. Chem. 2000 *Mannose|IGF2R protein, human|*Receptor, Mannose 6 Phosphate|Adaptor Protein Complex 1|Adaptor Protein Complex mu Subunits|Carrier Proteins|Adaptor Protein Complex 2|Membrane Proteins|Adaptor Proteins, Vesicular Transport|Clathrin|*Adaptor Proteins, Signal Transducing|Yeast Two-Hybrid System|Protein Transport|Amino Acid Sequence|Protein Binding|Cytoplasm|Phosphates | |
11071886 J. Biol. Chem. 2000 geldanamycin|*Lactams, Macrocyclic|*Benzoquinones|*HSP90 Heat-Shock Proteins|*Molecular Chaperones|glucose-regulated proteins|HSP70 Heat-Shock Proteins|ERBB2 protein, human|*Receptor, ErbB-2|Membrane Proteins|Protein Binding|Quinones|EGFR protein, human|Endoplasmic Reticulum|herstatin|*Intercellular Signaling Peptides and Proteins|Carrier Proteins|Ligands | |
11072085 Biochim. Biophys. Acta 2000 Humans|phospholipase D1|*Glycosylphosphatidylinositols|Exons|*Phospholipase D|RNA Splice Sites|Introns|mRNA|Alternative Splicing|Base Sequence|Amino Acid Sequence|cDNA|Cloning, Molecular|Liver|Blotting, Southern|In Situ Hybridization, Fluorescence | |
11073976 Mol. Cell. Biol. 2000 PMC86501 Mice|Animals|*Cyclin D3|CDKN1A protein, human|*Cyclin-Dependent Kinase Inhibitor p21|CDKN1B protein, human|*Cyclin-Dependent Kinase Inhibitor p27|Cyclin-Dependent Kinases|Cyclin-Dependent Kinase 4|CCND1 protein, human|Cyclin D1|Proto-Oncogene Proteins|Retinoblastoma Protein|Cell Cycle|Cyclin-Dependent Kinase 2|Microtubule-Associated Proteins|*Fibroblasts|Cyclin-Dependent Kinase Inhibitor p16|Phosphorylation | |
11073981 Mol. Cell. Biol. 2000 PMC86519 IRF7 protein, human|*Interferon Regulatory Factor-7|*Phosphorylation|*Transcriptional Activation|*Dimerization|Interferon Regulatory Factor-3|Cell Nucleus|Protein Binding|Amino Acid Sequence|Protein Processing, Post-Translational|DNA Sequence|Gene Expression Regulation|DNA | |
11073998 Mol. Cell. Biol. 2000 PMC86553 Humans|Animals|*RNA|Drosophila melanogaster|Nucleocytoplasmic Transport Proteins|Nucleoporins|Active Transport, Cell Nucleus|Cell Nucleus|Nuclear Proteins|RNA-Binding Proteins|mRNA|*Multigene Family|Amino Acid Sequence|Cytoplasm|Nuclear Envelope|Saccharomyces cerevisiae|Protein Binding|ATP-Binding Cassette Transporters|Sequence Alignment|Dimerization | |
11074001 Mol. Cell. Biol. 2000 PMC86556 Animals|Humans|*Telomerase|HeLa Cells|NOP10 protein, human|*Ribonucleoproteins, Small Nucleolar|Ribonucleoproteins, Small Nuclear|Saccharomyces cerevisiae|*Cell Nucleolus|NAP57|Nuclear Proteins|Saccharomyces cerevisiae Proteins|*Ribonucleoproteins|RNA-Binding Proteins|Small Nucleolar RNA|Coiled Bodies|Pre-rRNA|Amino Acid Sequence|Immunoprecipitation|Protein Binding | |
11075717 Endocr. J. 2000 INSR protein, human|*Receptor, Insulin|*Insulin|GRB2 protein, human|GRB2 Adaptor Protein|*Signal Transduction|Phosphorylation|*Antigens, CD|Phosphoproteins|Insulin Receptor Substrate Proteins|Shc Signaling Adaptor Proteins|Son of Sevenless Proteins|Adaptor Proteins, Vesicular Transport|ErbB Receptors|Tyrosine|Src Homology 2 Domain-Containing, Transforming Protein 1 | |
11076937 J. Biol. Chem. 2000 CDH1 protein, human|*E Cadherin|*Antigens, CD|*Apoptosis|CASP3 protein, human|Caspase 3|Caspases|Cell Adhesion|Cell Membrane|beta Catenin|Cell Adhesion Molecules|Cytoplasm|Epithelium | |
11076968 J. Cell Biol. 2000 PMC2169446 *Protein C|*Centrosome|Centrioles|Spindle Apparatus|Mitosis|Cell Cycle|Cell Cycle Proteins|Interphase|Microtubule|Protein-Serine-Threonine Kinases|NIMA-Related Kinases|*Cell Cycle Checkpoints|NCKAP1 protein, human|*Adaptor Proteins, Signal Transducing|Cytoskeletal Proteins|nucleic acid probe 1|*Oligopeptides|*Naphthalenes | |
11076969 J. Cell Biol. 2000 PMC2169435 Humans|Presenilin 2|Presenilin-1|Alzheimer Disease, Early Onset|Carrier Proteins|Cell Cycle Proteins|Protein Binding|Ubiquitin|Amino Acid Sequence|*Nuclear Proteins|Saccharomyces cerevisiae|Sequence Homology, Amino Acid|Cloning, Molecular | |
11076974 J. Cell Biol. 2000 PMC2169442 *Aquaporin 2|*Phosphorylation|AVP protein, human|Vasopressin|Protein Kinase A|Plasma Membrane|Cell Membrane Permeability|Serine|Aquaporin 6|Kidney|Oocytes|Neurophysins | |
11077054 Biochem. Pharmacol. 2000 Adult|Humans|SULT1C2 protein, human|*Sulfotransferases|Triiodothyronine|Thyroid Hormones|Substrate Specificity|Isoenzymes|Kinetics|Liver | |
11077116 Leuk. Res. 2000 *Homeodomain Proteins|*Cell Differentiation|Transcription Factors|Hematopoiesis|Hematopoietic Stem Cells|Protein Binding|mRNA|Thrombocytes|Monocytes|Hematopoietic Stem Cell Transplantation | |
11078440 Diabetes 2000 Humans|Animals|*Insulin Secretion|*Glucose|Diabetes Mellitus, Type 2|Insulin|Islets of Langerhans|Diazoxide|Insulin-Secreting Cells|Potassium Channels, Inwardly Rectifying|Exocytosis|Sulfonylurea Compounds|Adenosine Triphosphate|KATP Channels|Calcium | |
11078852 Am. J. Ophthalmol. 2000 Humans|Fundus Albipunctatus|Night Blindness|Electroretinography|retinol dehydrogenase|Alcohol Oxidoreductases|DNA Mutational Analysis|*Retinal Dystrophies|Pedigree|Mutation|Polymerase Chain Reaction | |
11080158 EMBO J. 2000 PMC305835 Animals|CTNNB1 protein, human|*beta Catenin|Transcription Factors|*Signal Transduction|Drosophila|DNA-Binding Proteins|TCF Transcription Factors|Trans-Activators|Nuclear Proteins|Lymphoid Enhancer-Binding Factor 1|Armadillo Domain Proteins|Drosophila Proteins|Wnt Proteins|TCF7 protein, human|T Cell Factor 1|Transcriptional Activation|Binding Sites|Protein Binding | |
11080452 J. Mol. Biol. 2000 Humans|RAD52 protein, human|*Rad52 DNA Repair and Recombination Protein|*DNA Repair|*Recombination, Genetic|Rad51 Recombinase|DNA, Single-Stranded|Single-Stranded DNA-Binding Protein|Replication Protein A|DNA|Nucleic Acid Conformation|Protein Binding|RAD51 protein, human | |
11080611 Cell. Signal. 2000 Animals|*Diacylglycerol Kinase|1,2-diacylglycerol|*Diglycerides|Signal Transduction|Phosphatidic Acid|Amino Acid Sequence|Isoenzymes|Second Messenger|Phosphorylation|Cell Nucleus|Catalytic Domain|Brain|Plasma Membrane | |
11080640 Structure 2000 Male|Animals|proacrosin|*Acrosin|Zona Pellucida|Zona Pellucida Glycoproteins|Egg Proteins|*Sperm|Acrosome|Enzyme Precursors|Receptors, Cell Surface|Membrane Glycoproteins|Acrosome Reaction|Binding Sites|*Mammals|Amino Acid Sequence | |
11080672 Biochim. Biophys. Acta 2000 Humans|Animals|*Phospholipases A2|Amino Acid Sequence|Cytosol|lysophosphatidic acid|Lysophospholipids|Substrate Specificity|Hydrolysis|Cell Line | |
11081627 Cell 2000 Humans|Animals|cohesins|*Anaphase|*Cell Cycle Proteins|*Chromosomal Proteins, Non-Histone|*Centromeres|*Mitosis|*Prophase|Chromatids|Separase|Nuclear Proteins|Chromosome Segregation|Saccharomyces cerevisiae Proteins|Metaphase|Saccharomyces cerevisiae|pituitary tumor-transforming protein 1, human|Securin|Phosphoproteins|Anaphase Promoting Complex | |
11081632 Cell 2000 Humans|*Ribonucleoprotein, U4-U6 Small Nuclear|*Spliceosomes|U4 small nuclear RNA|RNA, Small Nuclear|Ribonucleoproteins, Small Nuclear|*Ribonucleoproteins|Saccharomyces cerevisiae|snoRNP|RNA Splicing|RNA Precursors|Saccharomyces cerevisiae Proteins|Nucleic Acid Conformation|Base Sequence|Binding Site|Protein Binding|Cell Nucleolus | |
11081636 Cell 2000 Animals|*Proto-Oncogene Proteins c-met|*Listeria|inlB protein, Listeria monocytogenes|Membrane Proteins|Bacterial Proteins|HGF protein, human|Hepatocyte Growth Factor|Listeria monocytogenes|Phosphoproteins|Phosphorylation|Protein Binding|Signal Transduction|Ligands|Cell Lines | |
11082038 J. Cell. Sci. 2000 Rats|Animals|Lysosomes|Lysosome-Associated Membrane Glycoproteins|Molecular Chaperones|Intracellular Membranes|*Isoforms|Cytosol|Autophagy|Fibroblasts|Cells, Cultured | |
11082044 J. Cell. Sci. 2000 synaptojanin|Nerve Tissue Proteins|*Isoforms|Phosphoproteins|phosphoinositide 5-phosphatase|Phosphoric Monoester Hydrolases|src Homology Domains|*Endocytosis|Dynamin|Cytoskeletal Proteins|WASL protein, human|Wiskott-Aldrich Syndrome Protein, Neuronal|Amino Acid Sequence|Adaptor Proteins, Signal Transducing|Intracellular Signaling Peptides and Proteins|Carrier Proteins|Protein Binding|Dynamin I | |
11082198 Eur. J. Biochem. 2000 Animals|Swine|*Mannose, GDP|mannose 1-phosphate guanylyltransferase|glucose-1-phosphate guanylyltransferase|*Mannose|*Nucleotidyltransferases|GDP|Amino Acid Sequence|Guanosine Triphosphate|Sequence Homology, Amino Acid|Substrate Specificity|cDNA|Recombinant Proteins|*Liver|Escherichia coli|Cloning, Molecular | |
11083867 J. Biol. Chem. 2000 Animals|Humans|Cricetinae|5'(3')-nucleotidase|*5'-Nucleotidase|nucleotidase|*Nucleotidases|*Cytosol|Thymidine|Nucleosides|Deoxycytidine Kinase|Adenosine|Cell Lines|Cytidine|Hypoxanthine|Uridine|Kinetics|Nucleotides | |
11083877 J. Biol. Chem. 2000 Animals|Humans|*Tissue Distribution|Drosophila melanogaster|*Mitochondria|Mitochondrial Proteins|Carrier Proteins|Isoforms|Saccharomyces cerevisiae|cDNA|Base Sequence|Cytoplasm|Biological Transport|Amino Acid Sequence|2-Oxoglutarate|Sequence Homology, Amino Acid|Escherichia coli|Yeast Proteins|adipic acid|Adipates | |
11084045 J. Biol. Chem. 2000 Humans|Animals|MUC1 protein, human|*Mucin-1|*Promoter Regions, Genetic|Binding Site|Transcription Factors|Transcription Start Site|DNA-Binding Proteins|Transcription, Genetic|Trans-Activators|Gene Expression Regulation, Neoplastic|Mucin|Luciferase|Protein Binding|Interleukin 6|Cell Line, Tumor|Interferon-gamma | |
11084047 J. Biol. Chem. 2000 Humans|COMP protein, human|*Cartilage Oligomeric Matrix Protein|Pseudoachondroplasia|*Osteochondrodysplasias|*Achondroplasia|Matrilin Proteins|*Mutations|Cartilage|*Collagen Type I|Glycoproteins|*Calcium, Dietary|Chondrocytes|Collagen|Phenotypes|Amino Acid Sequence | |
11084335 Curr. Biol. 2000 Humans|BIRC7 protein, human|*Inhibitor of Apoptosis Proteins|*Neoplasm Proteins|*Adaptor Proteins, Signal Transducing|*Apoptosis|Caspases|Caspase 9|*Melanomas|Caspase Inhibitors|Amino Acid Sequence|Carrier Proteins|Sequence Homology, Amino Acid | |
11084340 Curr. Biol. 2000 synaptojanin|*Endocytosis|*Nerve Tissue Proteins|polyphosphoinositide phosphatase|*Phosphoric Monoester Hydrolases|cdc42 GTP-Binding Protein|Clathrin|rac1 GTP-Binding Protein|Actin Cytoskeleton|Signal Transduction|Pseudopodia|Actins|Plasma Membrane|Epidermal Growth Factor|Protein Transport|Growth Factor Receptors | |
11085925 Biochem. J. 2000 PMC1221463 Humans|Swine|Animals|*Asparagine|asparaginylendopeptidase|Cysteine Endopeptidases|Recombinant Proteins|Amino Acid Sequence|Enzyme Precursors|cDNA|Cell Line|Enzyme Activation|Transfections|Hydrogen-Ion Concentration | |
11085989 J. Biol. Chem. 2000 leptin receptor, human|*Receptors, Leptin|PTPN11 protein, human|*SHP-2 Protein-Tyrosine Phosphatase|Signal Transduction|Phosphorylation|Mitogen-Activated Protein Kinases|Protein Tyrosine Phosphatase, Non-Receptor Type 6|Trans-Activators|Protein-Tyrosine Kinases|Promoter Regions, Genetic|STAT5 Transcription Factor|Transcriptional Activation|EGR1 protein, human|Early Growth Response Protein 1 | |
11085990 J. Biol. Chem. 2000 Humans|DEFB103A protein, human|*beta-Defensins|Staphylococcus aureus|Keratinocytes|Escherichia coli|Anti-Bacterial Agents|Skin|Amino Acid Sequence|Gene Expression|Cells, Cultured|Recombinant Proteins|Cloning, Molecular|Cystic Fibrosis|Epithelium|Cells, Epithelial | |
11085997 J. Biol. Chem. 2000 Humans|Male|Animals|chitotriosidase|*Hexosaminidases|*Chitinases|Chitin|Amino Acid Sequence|Protein Binding|RNA, Messenger | |
11087364 Biochemistry 2000 PMC3060174 *Influenza A virus|*Amantadine|Viral Matrix Proteins|Protons|Ion Channel|Antiviral Agents|Hydrogen-Ion Concentration|Drug Resistance, Viral|Amino Acid Sequence|Protein Structure, Quaternary|Models, Molecular|Circular Dichroism|Peptides|Structure-Activity Relationship|Ultracentrifugation | |
11087732 J. Biol. Chem. 2000 Humans|epidermal growth factor receptor VIII|*Glycosylation|*Epidermal Growth Factor Receptor|EGFR protein, human|Phosphorylation|Epidermal Growth Factor|Transductions, Signal|Glioblastomas|Downregulation|Mutation|Kinetics|Dimerization|Protein Binding|Cell Line | |
11087742 J. Biol. Chem. 2000 *Nuclear Factor-Kappab|*Monocytes|APAF1 protein, human|*Apoptotic Protease-Activating Factor 1|CHUK protein, human|IKK gamma|Receptor-Interacting Protein Serine-Threonine Kinase 2|Nod1 Signaling Adaptor Protein|Signal Transduction|Adaptor Proteins, Signal Transducing|Apoptosis|Amino Acid Sequence|Protein Kinases | |
11087757 J. Biol. Chem. 2000 Humans|Mice|Animals|*Heparin|*Isoenzymes|Phylogeny|heparitin sulfotransferase|*Sulfotransferases|Heparitin Sulfate|Amino Acid Sequence|Amidohydrolases|cDNA|Cloning, Molecular | |
11089560 Endocrinology 2000 Rats|Humans|Animals|*Ghrelin|*Growth Hormone|*Human Growth Hormone|Receptors, Ghrelin|*Pituitary Hormones, Anterior|In Situ Hybridization|*Acylation|Messenger RNA|*Endocrine Cells|Gastric Mucosa|Gastric Fundus|Immunohistochemistry|*Gastrointestinal Tracts|*Drug Hypersensitivity | |
11090077 Blood 2000 Humans|Mice|Animals|STAT5A protein, human|*STAT5 Transcription Factor|*Leukemia, Myeloid, Acute|FLT3 protein, human|*fms-Like Tyrosine Kinase 3|*Mutations|Proto-Oncogene Proteins|Signal Transduction Pathways|*Tumor Suppressor Proteins|Tyrosine Kinase|Phosphorylation|Tandem Repeat Sequences|DNA-Binding Proteins|Trans-Activators|Cell Transformation, Neoplastic|Myeloid Cells|Intercellular Signaling Peptides and Proteins | |
11090136 Genes Dev. 2000 PMC317068 Animals|Hedgehog Proteins|Drosophila|Drosophila Proteins|DNA-Binding Proteins|Transcription Factors|Drosophila melanogaster|Signal Transduction|Protein-Serine-Threonine Kinases|Kinesin|*Protein Transport|Repressor Proteins|Cell Nucleus|Cytoplasm|Nuclear Import|Phosphorylation | |
11090627 Mol. Cell 2000 neutrophil cytosol factor 67K|*Tetratricopeptide Repeat|*Phosphoproteins|NADPH Oxidase|rac GTP-Binding Proteins|Superoxide|Enzyme Activation|Guanosine Triphosphate|Amino Acid Sequence|Neutrophils | |
11090634 Mol. Cell 2000 Humans|Animals|*Lymphoma, B-Cell, Marginal Zone|MALT1 protein, human|*Mucosa-Associated Lymphoid Tissue Lymphoma Translocation 1 Protein|Dictyostelium|*Caspases|BCL10 protein, human|B-Cell CLL-Lymphoma 10 Protein|Translocation, Genetic|Neoplasm Proteins|Mutation|NF-kappa B|Apoptosis|Adaptor Proteins, Signal Transducing|Signal Transduction | |
11092454 Cell. Mol. Life Sci. 2000 Humans|2',5'-oligoadenylate|*Synthetases|*Oligoribonucleotides|*Adenine Nucleotides|2',5'-Oligoadenylate Synthetase|Amino Acid Sequence|Interferons|Evolution, Molecular|Sequence Alignment|Phylogeny|Antiviral Agents|Multigene Family|Sequence Homology, Amino Acid|Exon|Intron|Interferon Inducers|RNA, Double-Stranded|Expressed Sequence Tag | |
11092856 J. Bacteriol. 2000 PMC94821 mycothiol|Inositol|Cysteine|Glycopeptides|Mycobacterium smegmatis|amidase|Amidohydrolases|Mycobacterium tuberculosis|Sulfhydryl Compounds|Bacterial Proteins|Disaccharides|Amino Acid Sequence | |
11094073 Mol. Cell. Biol. 2000 PMC102179 Mice|Animals|*Protein-Tyrosine Kinase, Receptor|*Signal Transduction|VAV3 protein, human|*Proto-Oncogene Proteins c-vav|GRB2 protein, human|GRB2 Adaptor Protein|Phosphorylation|Protein Binding|Proto-Oncogene Proteins|Adaptor Proteins, Vesicular Transport|INSR protein, human|Insulin Receptor|Shc Signaling Adaptor Proteins|EGFR protein, human|Epidermal Growth Factor Receptor|3T3 Cells|Phosphatidylinositol 3-Kinases|Cell Cycle Proteins | |
11094434 Arthritis Res. 2000 PMC130011 Mice|Animals|*Interleukin 1 Receptor Antagonist Protein|Interleukin-1|Receptors, Interleukin-1|Arthritis, Experimental|Arthritis, Rheumatoid|Mice, Knockout|Sialoglycoproteins|Disease Models, Animal|IL1A protein, human|Interleukin-1alpha | |
11095689 Nucleic Acids Res. 2000 PMC115166 Humans|*Saccharomyces cerevisiae|*Cell Cycle Proteins|MCM2-7 Complex|ORC2 protein, human|Origin Recognition Complex|Saccharomyces cerevisiae Proteins|DNA Replication|Replication Origins|S Phase|Schizosaccharomyces pombe|Yeast Two-Hybrid System|Cell Cycle|Chromatin|Cell Division|MCM10 protein, human|MCM10 protein, S cerevisiae|CDC23 protein, S cerevisiae|Apc8 Subunit, Anaphase-Promoting Complex-Cyclosome | |
11095724 Proc. Natl. Acad. Sci. U.S.A. 2000 PMC17668 Animals|*Ebola Virus|*Hemorrhagic Fever, Ebola|*Ubiquitin|Nucleoproteins|Endosomal Sorting Complexes Required for Transport|Viruses, Marburg|Virus Release|DNA-Binding Proteins|Ubiquitin-Protein Ligases|Ubiquitination|Viral Core Proteins|Transcription Factors|Nedd4 Ubiquitin Protein Ligases|Viral Matrix Proteins|Virion|Cell Line|*Rhabdoviruses | |
11095984 Biochem. Biophys. Res. Commun. 2000 Humans|*ATP-Binding Cassette Transporters|*Cholesterol|Exons|Introns|Base Sequence|*Genomics|DNA, Complementary|ARHGAP45 protein, human|*Minor Histocompatibility Antigens|HA-1 antigen|Promoter Regions, Genetic|Amino Acid Sequence|RNA, Messenger|*Oligopeptides|*Genetic Linkage|Macrophages|GTPase-Activating Proteins|ABCA7 protein, human | |
11096062 J. Biol. Chem. 2000 Animals|Humans|*Saccharomyces cerevisiae|*Enzyme Activators|Saccharomyces cerevisiae Proteins|Autophagy-Related Protein 7|Autophagy-Related Protein 8 Family|Autophagy-Related Proteins|Microtubule-Associated Protein 3|Amino Acid Sequence|Autophagy-Related Protein 12|Autophagy-Related Protein 5|Ubiquitin-Conjugating Enzymes|Sequence Homology, Amino Acid|Autophagy|Ubiquitin-Protein Ligases|Protein Binding|Vacuole|Cytosol|Mutagenesis, Site-Directed | |
11096114 J. Biol. Chem. 2000 Humans|*Transformylase|*Dimerization|4-aminoimidazole|IMP cyclohydrolase|*Nucleotide Deaminases|*Phosphoribosylaminoimidazolecarboxamide Formyltransferase|AICA ribonucleotide|Ribonucleotides|*Protein Dimerization|Aminoimidazole Carboxamide|Kinetics|Multienzyme Complexes|Protein Conformation|Binding Sites|Catalysis|purine|Purines|Models, Molecular | |
11098060 J. Biol. Chem. 2000 Humans|*Caspases|*TNF Receptor-Associated Factor 1|HEK293 Cells|TNFRSF1A protein, human|*Receptors, Tumor Necrosis Factor, Type I|*Tumor Necrosis Factor Receptor|*Apoptosis|TRAF2|Procaspase-8|Nuclear Factor-Kappab|fas Receptor|Tumor Necrosis Factor-alpha|Caspase 9|Cell Death|Signal Transduction|Adaptor Proteins, Signal Transducing|HeLa Cells | |
11099047 Nature 2000 TP53 protein, human|*Tumor Suppressor Protein p53|HDAC1 protein, human|Histone Deacetylase 1|Histone Deacetylases|*Apoptosis|NuRD Complex|Activation, Transcriptional|Acetylation|DNA-Binding Proteins|Repressor Proteins|Transcription Factor|Promoter Regions, Genetic|*Cell Cycle | |
11099377 J. Mol. Biol. 2000 Cricetinae|Humans|Rats|Animals|UDP xylose-protein xylosyltransferase|*Xylose|*Cloning, Molecular|*Pentosyltransferases|DCN protein, human|*Decorin|Amino Acid Sequence|*Protein Isoforms|Proteoglycans|PCR|Chondroitin Sulfates|Heparitin Sulfate|Exon|Transfections|Glycosaminoglycans|Intron|Heparin|Open Reading Frame | |
11099414 Science 2000 Humans|*Mitochondria|Bid Protein|*Apoptosis|CASP8 protein, human|Caspase-8|Caspases|Proto-Oncogene Proteins c-bcl-2|Carrier Proteins|*Myristic Acid|Caspase 9|fas Receptor|Jurkat Cells|Cytosol|Cytochrome c Group | |
11099417 Science 2000 Humans|Mice|Animals|Sitosterolemia|*Cholesterol, Dietary|*Hypercholesterolemia|*Transporters, ABC|*Phytosterols|*Lipid Metabolism, Inborn Errors|ATP Binding Cassette Transporter, Subfamily G, Member 5|ATP Binding Cassette Transporter, Subfamily G, Member 8|*Intestinal Diseases|Cholesterol|Sitosterols|Lipoproteins|Orphan Nuclear Receptors|*Mutations|Liver X Receptors|Intestinal Absorption|Bile|Liver | |
11100717 Nature 2000 PMC2981135 Humans|Female|BRCA2 protein, human|*BRCA2 Protein|BRCA1 protein, human|*BRCA1 Protein|Genes, BRCA1|*Genes, Tumor Suppressor|Ovarian Cancer|Transcription Factors|Neoplasm Proteins|Mutations, Germline|DNA Repair|Cell Cycle | |
11101512 EMBO J. 2000 PMC305865 Humans|*Mitochondria|Mitochondrial Proteins|Mitochondrial Membrane Transport Proteins|Carrier Proteins|Saccharomyces cerevisiae Proteins|Intracellular Membranes|Membrane Transport Proteins|Saccharomyces cerevisiae|Membrane Proteins|Biological Transport|Amino Acid Sequence|Membrane Potential|TIM23 protein, S cerevisiae|TIM10 protein, S cerevisiae|Tim9 protein, S cerevisiae | |
11101518 EMBO J. 2000 PMC305878 *Membrane Fusion|Syntaxin 1|SNAP25 protein, human|Synaptosomal-Associated Protein 25|Syntaxin 7|*Protein Binding|*Endosomes|R-SNARE Proteins|Vesicular Transport Proteins|Nerve Tissue Proteins|Carrier Proteins|Protein Structure, Tertiary|Qb-SNARE Proteins|Amino Acid Sequence|Exocytosis|Binding Sites|Sequence Homology, Amino Acid | |
11101529 EMBO J. 2000 PMC305846 Humans|Spliceosome|RNA Splicing|RNA Precursors|Cell Cycle Proteins|Schizosaccharomyces pombe|Carrier Proteins|*Mass Spectrometry|RNA, Messenger|HeLa Cells|Amino Acid Sequence|Sequence Homology, Amino Acid|RNA|CDC5L protein, human|RNA-Binding Proteins | |
11101534 EMBO J. 2000 PMC305848 *Ribosomes|Saccharomyces cerevisiae Proteins|Saccharomyces cerevisiae|Peptide Elongation Factors|*Amino Acids|*Protein Binding|Phosphorylation|Protein-Serine-Threonine Kinases|Protein Kinases|DNA-Binding Proteins|Eukaryotic Initiation Factor-2|tRNA|Amino Acid Sequence|Phenotype|Binding Sites|GCN2 protein, S cerevisiae | |
11101851 Nat. Genet. 2000 Animals|Humans|*Notch Receptors|*Drosophila|Drosophila melanogaster|*Transcription Factors|DNA Binding Protein|Nuclear Proteins|Drosophila Proteins|Trans-Activators|Membrane Proteins|Signal Transduction|Repressor Proteins|Transcriptional Activation|Receptor, Notch1|Binding Protein|Cell Nucleus|MAML1 protein, human|mastermind protein, Drosophila|notch protein, Drosophila | |
11101887 Nat. Struct. Biol. 2000 Humans|*Peroxisomal Targeting Signals|*Tetratricopeptide Repeat|Peroxisome-Targeting Signal 1 Receptor|Peroxisomes|Binding Site|Amino Acid Sequence|Protein Binding|Receptors, Cytoplasmic and Nuclear|Peptides | |
11101902 Nat. Struct. Biol. 2000 PMC4381838 Mice|Animals|*Wnt Signaling Pathway|Dishevelled Proteins|Phosphoproteins|Adaptor Proteins, Signal Transducing|Wnt Proteins|Transcription Factor, LEF-1|Frizzled Receptors|Transcription Factors|DNA-Binding Proteins|beta Catenin|Binding Site|Protein Binding|Amino Acid Sequence|Zebrafish Proteins|Dvl1 protein, mouse | |
11102458 J. Neurosci. 2000 PMC6773050 Animals|Mice|*Protein Kinase A|NBEA protein, human|*Carrier Proteins|*Nerve Tissue Proteins|Golgi Apparatus|*Protein Sorting|Brefeldin A|ADP-Ribosylation Factor|GTPgammaS|Intracellular Membranes|Amino Acid Sequence|GTP-Binding Proteins|Phosphoproteins|Membrane Proteins|COPI|(T,G)-A-L|Peptides|Protein Binding | |
11102867 Curr Opin Chem Biol 2000 Glycosylphosphatidylinositols|Acylation|Inositol|Acetylglucosamine|Chromatography, Thin Layer | |
11103799 Cancer Res. 2000 *Estrogens|Receptors, Estrogen|Tamoxifen|Estradiol|*Regulatory Genes|Gene Expression Regulation, Neoplastic|Neoplasm Proteins|Tumor Cells, Cultured|Gene Expression Profiling|RNA, Messenger | |
11104681 Biochem. J. 2000 PMC1221512 anthrax toxin|*Proteolysis|*Antigens, Bacterial|*Bacterial Toxins|*MAPKK|Bacillus anthracis|MAP Kinase Kinase 2|MAP Kinase Signaling System|Substrate Specificity|Protein-Tyrosine Kinases|Amino Acid Sequence | |
11104777 J. Biol. Chem. 2000 Rats|Animals|Pitpna protein, rat|*Phospholipid Transfer Proteins|*Lecithins|Phosphatidylinositol|Carrier Proteins|Phospholipids|Crystallography, X-Ray|Protein Isoforms|Models, Molecular|Lipid Metabolism|Ligands|*Mammals|Biological Transport | |
11104795 J. Clin. Invest. 2000 PMC381469 *Pro-Opiomelanocortin|STAT3 protein, human|*STAT3 Transcription Factor|*Pituitary Gland|LIF protein, human|Inhibitory Factor, Leukemia|*Pituitary Diseases|Corticotrophin|DNA-Binding Proteins|Interleukin-6|Corticotropin-Releasing Hormone|Suppressor of Cytokine Signaling 3 Protein|Trans-Activators|Gene Expression|Suppressor of Cytokine Signaling Proteins|Hypothalamus|Promoter Regions, Genetic|Repressor Proteins | |
11106645 J. Biol. Chem. 2000 Humans|Rats|Mice|Animals|*Collagen Type I|*Osteoblast|Transcription Factors|Promoter Regions, Genetic|Core Binding Factor Alpha 1 Subunit|Binding Site|Transcription, Genetic|Transfection|Gene Expression Regulation|Base Sequence|Neoplasm Proteins|Cell Line|DNA|Cell Differentiation|Electrophoretic Mobility Shift Assay | |
11106668 J. Biol. Chem. 2000 Humans|Animals|*Caspases|CASP3 protein, human|Caspase 3|BIRC2 protein, human|Inhibitor of Apoptosis Proteins|Apoptosis|Caspase 8|Transfection|Tumor Necrosis Factor-alpha|Protein Structure, Tertiary|Cell Death|Amino Acid Sequence|Protein Binding|Binding Sites|E3 Ligase | |
11106738 Mol. Cell 2000 Male|Mice|Animals|Meiosis|Saccharomyces cerevisiae|Caenorhabditis elegans|*Synapsis|meiotic recombination protein SPO11|Endodeoxyribonucleases|Spermatocytes|*Chromosomes|DNA Breaks, Double-Stranded|Meiotic Prophase I|Cell Cycle Proteins|DNA Repair|Recombination, Genetic|Nuclear Proteins|Esterases|DMC1 protein, S cerevisiae|DNA-Binding Proteins|Saccharomyces cerevisiae Proteins | |
11106739 Mol. Cell 2000 Male|Mice|Animals|*Synapsis, Chromosomal|meiotic recombination protein SPO11|*Endodeoxyribonucleases|Spermatocytes|Meiosis|Diplotene Stage|Chromosome|DNA Breaks, Double-Stranded|Cell Cycle Proteins|DNA Repair|Nuclear Proteins|Recombination, Genetic|DNA-Binding Proteins|Oocytes|Esterases | |
11106749 Mol. Cell 2000 Mice|Animals|Eukaryotic Initiation Factor-2|eIF-2 Kinase|Activating Transcription Factor 4|Phosphorylation|*Protein Processing, Post-Translational|Transcription Factor CHOP|Protein-Serine-Threonine Kinases|Signal Transduction|Endoplasmic Reticulum|Protein Folding|Protein Biosynthesis|Carrier Proteins|CCAAT-Enhancer-Binding Proteins|Unfolded Protein Response|mRNA | |
11108241 Endocrinology 2000 Humans|Rabbits|Mice|Animals|ADAM17 protein, human|*ADAM17 Protein|*Proteolysis|somatotropin-binding protein|*Binding Protein|Receptors, Somatotropin|*Metalloproteases|phorbol-12-myristate|JAK2 protein, human|Janus Kinase 2|Metalloendopeptidases|Tetradecanoylphorbol Acetate|Growth Hormone|Cell Line|Transfection|Downregulation|*Acetates | |
11108838 FEBS Lett. 2000 Humans|Mice|Animals|leptin receptor, mouse|leptin receptor, human|*Receptors, Leptin|*Suppressor of Cytokine Signaling Proteins|Signal Transduction|Transcription Factors|Leptin|Suppressor of Cytokine Signaling 3 Protein|Repressor Proteins|Phosphorylation|Receptors, Cell Surface|Tyrosine|SOCS3 protein, human|Socs3 protein, mouse | |
11108845 FEBS Lett. 2000 Animals|Chlorocebus aethiops|*Neuropilin-1|*Semaphorin-3A|*Small GTPases|plexin|Nerve Tissue Proteins|Growth Cones|Cell Adhesion Molecules|Semaphorins|Transductions, Signal|rho GTP-Binding Proteins|Axons|GTPase-Activating Proteins|ras GTPase-Activating Proteins|COS Cells | |
11110698 Blood 2000 Mice|Animals|*Blood Platelets|*Phosphorylation|Platelet Activation|*Receptors, IgG|src-Family Kinases|Platelet Membrane Glycoproteins|Platelet Glycoprotein GPIIb-IIIa Complex|Signal Transduction|collagen-related peptide|Carrier Proteins|Proto-Oncogene Proteins c-fyn|Phospholipase C gamma|Peptides|Receptors, Fc|Proto-Oncogene Proteins|Collagen|Fyn protein, mouse | |
11111046 Gene 2000 Humans|Saccharomyces cerevisiae|MOD5 protein, S cerevisiae|*Alkyl and Aryl Transferases|tRNA isopentenyltransferase|Saccharomyces cerevisiae Proteins|tRNA|Transferases|Genetic Complementation Test|Amino Acid Sequence|Cloning, Molecular|Base Sequence|cDNA|Sequence Homology, Amino Acid|Isopentenyladenosine | |
11112443 Biochem. Biophys. Res. Commun. 2000 Animals|Humans|*sPLA(2)|Cloning, Molecular|Recombinant Proteins|Amino Acid Sequence|Phospholipids|cDNA|Sequence Homology, Amino Acid|Escherichia coli|Gene Expression|Hydrolysis|Tissue Distribution|Phosphatidyl Choline | |
11112487 Virology 2000 *HIV-1|p16 protease, Human immunodeficiency virus 1|HIV Protease|*Leukemia Virus, Murine|gag Gene Products, Human Immunodeficiency Virus|Virions|Virus Replication|*Ubiquitination|Ubiquitin|Amino Acid Sequence|Cell Line|*HIV Seropositivity | |
11112695 J. Cell. Sci. 2000 *Matrix Metalloproteinase 7|MMP3 protein, human|*Matrix Metalloproteinase 3|CDH1 protein, human|*E Cadherin|Cell Adhesion|Cell Aggregation|Antigens, CD|Cell Membrane|Collagen Type I | |
11114298 J. Biol. Chem. 2000 *Cytochromes c|GZMB protein, human|*Granzymes|*Mitochondrial Transmembrane Permeability-Driven Necrosis|Caspases|*Carrier Proteins|BH3 Interacting Domain Death Agonist Protein|Mitochondria|Apoptosis|Caspase 9|Caspase 8|Proto-Oncogene Proteins c-bcl-2|Caspase 3|Cytosol|Apoptosis Regulatory Proteins | |
11114305 J. Biol. Chem. 2000 *Interleukin-6|*Promoter Regions, Genetic|STAT3 protein, human|*STAT3 Transcription Factor|*Gene Expression Regulation|Transcription, Genetic|CCAAT-Enhancer-Binding Protein-beta|Binding Sites|Response Elements|CCAAT-Enhancer-Binding Proteins|Trans-Activators|Transfection|Reporter Gene | |
11114375 Immunity 2000 CD100 antigen|*Semaphorin|CD72 protein, human|*Antigens, CD|*B-Lymphocytes|Antigens, Differentiation, B-Lymphocyte|*Lymphocyte|*Signal Transduction|Lymphocyte Activation|CD40 Antigens|Membrane Glycoproteins|Responses, Antibody | |
11114383 Immunity 2000 Humans|Animals|Mice|*IL 12|IL12B protein, human|*Interleukin-12 Subunit p40|IL12RB2 protein, human|Receptors, Interleukin-12|*Cytokines|Interleukin-23|IL12RB1 protein, human|TYRP1 protein, human|*Membrane Glycoproteins|Interferon-gamma|*Signal Transduction|CD4-Positive T-Lymphocytes|Protein Subunits | |
11114888 Genes Dev. 2000 PMC317107 BRCA1 protein, human|*BRCA1 Protein|*Genotoxic Stress|CHEK1 protein, human|*Checkpoint Kinase 1|Ataxia Telangiectasia Mutated Proteins|Cell Cycle Proteins|Phosphorylation|Tumor Suppressor Proteins|DNA Repair|DNA-Binding Proteins|UV Light|Genes, BRCA1|Aphidicolin | |
11115402 Biochem. J. 2000 PMC1221546 Animals|Humans|*Arachidonate 12-Lipoxygenase|*Arachidonic Acid|*Phospholipid Hydroperoxide Glutathione Peroxidase|*Blood Platelets|Glutathione Peroxidase|12-HPETE|Leukotrienes|Oxidation-Reduction|Selenium|*Lipid Metabolism|12-HETE|Oxidative Stress|*Biochemical Phenomena|mRNA|Tumor Cells, Cultured | |
11115854 Hum. Mol. Genet. 2000 Animals|*Utrophin|*Dystroglycans|*Sarcoglycans|SSPN protein, human|Dystrophin|*Cell Membrane|Carrier Proteins|Neoplasm Proteins|Schwann Cells|Sarcolemma|Laminin|Nerve, Peripheral|Glycoprotein|*Peripheral Nervous System|Protein Isoforms|Myelin Sheath | |
11117535 Mol. Endocrinol. 2000 Humans|activin B|*Activin|*Signal Transduction|Activin Receptors, Type I|*Isoforms|Activin Receptors|Pituitary Tumors|Inhibins|Receptors, Transforming Growth Factor beta|Activin Receptors, Type II|Receptors, Growth Factor|Protein-Serine-Threonine Kinases|Adenoma|Transforming Growth Factor beta|Gene Expression|Phosphorylation|Transfections|K562 Cells | |
11118210 EMBO J. 2000 PMC305902 Humans|*Active Transport, Cell Nucleus|*Influenza A virus|Nuclear Export Signals|Karyopherins|Receptors, Cytoplasmic and Nuclear|TYRP1 protein, human|*Membrane Glycoproteins|Viral Nonstructural Proteins|Cell Nucleus|Amino Acid Sequence|Noonan Syndrome 2|*Noonan Syndrome|Cell Line | |
11118213 EMBO J. 2000 PMC305881 *PDZ Domains|*Transcription Factors|DNA-Binding Proteins|Phosphoproteins|Nuclear Proteins|Transcription, Genetic|Intracellular Signaling Peptides and Proteins|Adaptor Proteins, Signal Transducing|Cell Nucleus|Carrier Proteins|Activation, Transcriptional|Protein Binding|Signal Transduction|Cytoplasm|Export, Nuclear|Phosphorylation | |
11118217 EMBO J. 2000 PMC305894 Humans|*RNA Polymerase III|NFIB protein, human|*NFI Transcription Factors|transcription factor TFIIIC|Transcription Factors, TFIII|Transcription, Genetic|Terminator Regions, Genetic|Binding Sites|Promoter Regions, Genetic|Base Sequence | |
11118221 EMBO J. 2000 PMC305905 Humans|*Spliceosomes|*mRNA|*Nucleotides|HeLa Cells|*Exon|messenger ribonucleoprotein|Ribonucleoproteins|RNA Splicing|RNA Precursors|RNA-Binding Proteins|Nuclear Proteins|Cell Nucleus|Transport, Nucleo-cytoplasmic|Cytoplasm|Dek protein, human|Poly-ADP-Ribose Binding Proteins|Chromosomal Proteins, Non-Histone|Oncogene Proteins | |
11118334 Biochem. Biophys. Res. Commun. 2000 Humans|*Histamine Receptor|N-methylhistamine|Methylhistamines|H3 Receptor, Histamine|H3 Agonist|alpha-methylhistamine|Histamine|imetit|Imidazoles|*Cloning, Molecular|8-chloro-cyclic adenosine monophosphate|8-Bromo Cyclic Adenosine Monophosphate|Cyclic AMP|Amino Acid Sequence|cDNA|Thiourea|Forskolin|Cells, Cultured | |
11118617 Biochim. Biophys. Acta 2000 Animals|Humans|*Phospholipase C beta|*Phosphatidylinositol|cDNA|Amino Acid Sequence|Base Sequence|Cloning, Molecular|Type C Phospholipases|Alternative Splicing|Isozymes|Sequence Homology, Amino Acid | |
11119712 FEBS Lett. 2000 Humans|Mice|Animals|*Endostatins|*Proteinases|Collagen XVIII|Cathepsin L|Cathepsins|Angiogenesis Inhibitors|Amino Acid Sequence|Collagen|Neovascularization, Pathologic|Peptide Fragments|Blotting, Western | |
11120601 Exp. Cell Res. 2000 Humans|lonafarnib|*Pyridines|*Piperidines|*Enzyme Inhibitors|Farnesyltranstransferase|M Phase|Cell Cycle|CDKN1A protein, human|Cyclin-Dependent Kinase Inhibitor p21|*Tumor Cell Lines|ras Proteins|Apoptosis | |
11120780 J. Exp. Med. 2000 PMC2213502 STAT3 protein, human|*STAT3 Transcription Factor|BCL6 protein, human|*Proto-Oncogene Proteins c-bcl-6|DNA-Binding Proteins|Repressor Proteins|Plasma Cells|Germinal Center|Positive Regulatory Domain I-Binding Factor 1|B-Lymphocytes|Cell Differentiation|Proto-Oncogene Proteins|*Lymphocyte Activation | |
11120840 J. Immunol. 2000 Humans|GNLY protein, human|*Antigens, Differentiation, T-Lymphocyte|*Cell Membrane Permeability|NK-lysin|Proteolipids|Mycobacterium tuberculosis|T-Lymphocytes, Cytotoxic|*Permeability|Amino Acid Sequence|Peptides|NK Cells|Escherichia coli | |
11121022 Proc. Natl. Acad. Sci. U.S.A. 2000 PMC18885 AR protein, human|*Receptors, Androgen|SUMO-1 Protein|Small Ubiquitin-Related Modifier Proteins|Ubiquitin-Conjugating Enzymes|Sumoylation|Transcription, Genetic|Binding Sites|Transcription Factors|Protein Binding|Amino Acid Sequence|Gene Expression Regulation|Ligands|Blotting, Western | |
11121027 Proc. Natl. Acad. Sci. U.S.A. 2000 PMC18897 carbonic anhydrase XII|*Kinetics|carbonic anhydrase VI|*Carbonic Anhydrase|Catalysis|Proton|*Cancers|Hydrogen-Ion Concentration|Amino Acid Sequence|Carbon Dioxide|Binding Sites|Mutagenesis, Site-Directed|*Membrane|Zinc|Water|Tumor Microenvironment | |
11121043 Proc. Natl. Acad. Sci. U.S.A. 2000 PMC18929 Mice|Animals|*Xenopus laevis|Bone Morphogenetic Proteins|*Signal Transduction|SMAD5 protein, human|Smad5 Protein|Transforming Growth Factor beta|SMAD4 protein, human|Smad4 Protein|Smad Proteins|*Gene Expression Regulation|Smad1 Protein|Cell Differentiation|Trans-Activators|Xenopus Proteins|Bone Morphogenetic Protein 2|Phosphorylation|Protein-Serine-Threonine Kinases|Receptors, Cell Surface | |
11121055 Proc. Natl. Acad. Sci. U.S.A. 2000 PMC18954 Humans|FGFR2 protein, human|*Receptor, Fibroblast Growth Factor, Type 2|*Acrocephalosyndactylia|Mutation|Fibroblast Growth Factors|Craniosynostoses|Point Mutation|Phenotype|Ligands | |
11121117 Eur. J. Biochem. 2000 Humans|*Cytokine Receptor gp130|IL6R protein, human|Receptors, Interleukin-6|Interleukin 6|LIF protein, human|Inhibitory Factor, Leukemia|Oncostatin M|Antigens, CD|Membrane Glycoproteins|Recombinant Proteins|Signal Transduction|Protein Binding|Enzyme-Linked Immunosorbent Assay|Cell Membrane | |
11121482 Nucleic Acids Res. 2000 PMC115236 Humans|8-hydroxyguanine|*Adenine|*Base Pairing|*Excision Repair|*Guanine|DNA Glycosylases|Deoxyribonuclease IV (Phage T4-Induced)|*Double-Stranded DNA|DNA-(Apurinic or Apyrimidinic Site) Lyase|DNA-Formamidopyrimidine Glycosylase|Escherichia coli Proteins|Escherichia coli|Base Pair Mismatch|DNA Damage|Carbon-Oxygen Lyases | |
11123271 J. Immunol. 2000 TLR2 protein, human|*Toll-Like Receptor 2|*Toll-Like Receptor 1|*Toll-Like Receptor 6|staphylococcal delta toxin|Toll-Like Receptor|*Bacterial Toxins|Toll-Like Receptor 4|lipoteichoic acid|Lipopolysaccharides|Teichoic Acids|Membrane Glycoproteins|Carrier Proteins|NF-kappa B|Signal Transduction|Drosophila Proteins|Cell Line | |
11123320 J. Immunol. 2000 Humans|Cricetinae|Animals|Rabbits|*Chickens|CHO Cells|*Protein A|Cricetulus|*Complement|CD46 protein, human|Membrane Cofactor Protein|*Cloning, Molecular|CD55 Antigens|Base Sequence|Complement Inactivator Proteins|Amino Acid Sequence|Antigens, CD|Membrane Glycoproteins|cDNA|Transfections | |
11123914 Biochemistry 2000 Humans|*Adenosinetriphosphatase|ABCA4 protein, human|*ATP-Binding Cassette Transporters|*Protein Binding|*Nucleotides|*Retina|Rod Outer Segment|Kinetics|Adenosine Triphosphate|Age Related Macular Degeneration|Hydrolysis|Protein Structure, Tertiary|Membrane Transport Proteins|Amino Acid Sequence|Protein Structure, Secondary|Plasmid|Mutation | |
11123935 Biochemistry 2000 Humans|GUCY2C protein, human|*Receptors, Enterotoxin|Receptors, Guanylate Cyclase-Coupled|Guanylyl Cyclase|Receptors, Peptide|Enterotoxins|*Carrier Proteins|Amino Acid Sequence|*Cytoplasm|guanylin|Natriuretic Peptides|Recombinant Proteins|Signal Transduction|Gastrointestinal Hormones|Kinetics|Protein Kinases|manganese GTP|Guanosine Triphosphate | |
11124251 J. Biol. Chem. 2000 Rats|Animals|GJA1 protein, human|*Connexin43|*Junction Protein, Gap|Gap Junctions|*Cell Communication|*Protein-Tyrosine Kinases|Phosphorylation|src Kinases|Cell Transformation, Neoplastic|Tyrosine|Mutation|Fibroblasts | |
11124902 J. Mol. Biol. 2000 *beta Karyopherins|ran GTP-Binding Protein|Karyopherins|Nuclear Proteins|Protein Binding|Cell Nucleus|Cytoplasm|Protein Conformation|Importin-alpha|Binding Sites|Guanosine Triphosphate|Models, Molecular|Biological Transport|Mutations | |
11124936 J. Biol. Chem. 2001 Humans|IL3 protein, human|*Interleukin-3|*Integrin beta1|*Cell Adhesion|EPO protein, human|*Erythropoietin|RAP1A protein, human|rap1 GTP-Binding Proteins|CRKL protein|Adaptor Proteins, Signal Transducing|Nuclear Proteins|*Epoetin Alfa|Signal Transduction|FN1 protein, human|Fibronectin|*Protein Binding|Guanine Nucleotide Exchange Factor|Hematopoietic Stem Cells | |
11124955 J. Biol. Chem. 2001 *Consensus|SUMO-1 Protein|*SUMO-Conjugation|Ubiquitins|NFKBIA protein, human|IKappaBalpha|*Cell Nucleus|Amino Acid Sequence|DNA-Binding Proteins|Binding Sites|Tumor Suppressor Protein p53|Nuclear Localization Signal|Transcriptional Activation | |
11124962 J. Biol. Chem. 2001 Animals|*mRNA|Heterogeneous-Nuclear Ribonucleoprotein D|*RNA, Small Nuclear|RNA|Protein Binding|Nucleic Acid Conformation|Protein Isoforms|Binding Sites|TNF protein, human|TNFalpha|Cytoplasm|Kinetics|Heterogeneous Nuclear Ribonucleoprotein D0|Ions | |
11125146 Science 2000 GMNN protein, human|*Geminin|*Eukaryotes|Cell Cycle|S Phase|Replication Origins|DNA Replication|DNA-Binding Proteins|Chromatin|Protein Binding|Xenopus Proteins|Cell Nucleus|*Eukaryotic Cells|DNA | |
11130076 Nature 2000 BAIAP2 protein, human|*Nerve Tissue Proteins|WASL protein, human|Wiskott-Aldrich Syndrome Protein, Neuronal|Wiskott-Aldrich Syndrome Protein Family|Actins|WASP Protein|Microfilament Proteins|Arp2-3 Complex|rac GTP-Binding Proteins|Protein Binding|Amino Acid Sequence | |
11133365 Am. J. Hum. Genet. 2001 PMC1235266 Humans|Mice|Animals|periaxin|*Membrane Proteins|*Mutations|Hereditary Sensory and Motor Neuropathy|Point Mutation|Pedigree|Homozygote|Amino Acid Sequence|Codon, Nonsense|Sheaths, Myelin|Sural Nerve | |
11133510 Am. J. Physiol. Renal Physiol. 2001 Humans|Animals|*Glucose|SLC5A1 protein, human|Sodium-Glucose Transporter 1|SLC5A2 protein, human|Sodium-Glucose Transporter 2|*Sodium|*Kidneys|Monosaccharide Transport Proteins|Membrane Glycoproteins|Kidney Tubules, Proximal|Brush Border|Cell Membrane|Amino Acid Sequence|Carbohydrates|Xenopus laevis|Oocytes|RNA, Messenger | |
11133996 J. Biol. Chem. 2001 Male|Female|Humans|*5'-Nucleotidase|HEK293 Cells|nucleotidase|*Nucleotidases|*Cytosol|2-Chloro-2'-deoxyadenosine|gemcitabine|Deoxycytidine|DCMP protocol|Cytarabine|Phosphorylation|Amino Acid Sequence|Substrate Specificity|Antineoplastic Combined Chemotherapy Protocols|Daunorubicin|Prednisolone|Mercaptopurine | |
11134001 J. Biol. Chem. 2001 Animals|Humans|*Bilirubin|HEK293 Cells|*Organic Anion Transporters|Sulfobromophthalein|*Liver|*Biological Transport|Hepatocytes|Carrier Proteins|Anion Transport Proteins|Xenopus laevis|Glucuronates|Indocyanine Green | |
11134074 J. Cell Biol. 2001 PMC2150672 Mice|Animals|PAK1 protein, human|*p21-Activated Kinases|protein kinase N|*Protein Kinase C|Filopodia|*Fibroblasts|Cytoskeleton|Actin|cdc42 GTP-Binding Protein|rac1 GTP-Binding Protein|Phosphatidylinositol 3-Kinases|Phosphorylation|Wortmannin|Platelet-Derived Growth Factor|NIH 3T3 Cells|Focal Adhesion|Cell Movement|EGFR protein, human | |
11134534 Proc. Natl. Acad. Sci. U.S.A. 2001 PMC14555 Animals|Cyclin B|histone H1 kinase|Protein Kinases|Xenopus laevis|CDC2 Protein Kinase|Phosphorylation|Xenopus Proteins|Protein-Serine-Threonine Kinases|cdc25 Phosphatases|Mitosis|G2 Phase|Enzyme Activation|Oocytes|Cell Cycle Checkpoints|Cdc25C protein, Xenopus | |
11135303 Bioessays 2001 Receptors, Notch|Signal Transduction|Cell Differentiation|Membrane Proteins|Nervous System|Morphogenesis | |
11136719 J. Biol. Chem. 2001 Animals|Humans|condensin complexes|*Xenopus laevis|HeLa Cells|Adenosine Triphosphatases|DNA-Binding Proteins|Multiprotein Complexes|Chromosomes|Cell Cycle Proteins|Chromosomal Proteins, Non-Histone|Mitosis|Nuclear Proteins|*Chromosome Structures|Phosphorylation|Chromosome Segregation|DNA, Superhelical|Carrier Proteins|Protein Subunits|TOP1 protein, human | |
11136736 J. Biol. Chem. 2001 Humans|*Mitochondrial Membranes|*bcl-2-Associated X Protein|HeLa Cells|*Molecular Weight|BCL2 protein, human|Proto-Oncogene Proteins c-bcl-2|Mitochondria|BH3 Interacting Domain Death Agonist Protein|Staurosporine|Proto-Oncogene Proteins|Apoptosis|Carrier Proteins|Membrane Proteins|Cytosol|Voltage-Dependent Anion Channels|Cytochrome c Group | |
11136970 Cell 2001 *Receptors, Estrogen|G-T mismatch-binding protein|DNA-Binding Proteins|*Gene Expression Regulation|Tamoxifen|Gene Activation|Estrogen Receptor alpha|Estrogens|Nuclear Proteins|Nuclear Receptor Coactivator 1|Promoter Regions, Genetic|Estradiol|Histone Acetyltransferases|Nuclear Receptor Coactivator 2|Trans-Activators|Response Elements|Binding Sites | |
11136974 Cell 2001 CTNNB1 protein, human|*beta Catenin|TCF7L1 protein, human|Transcription Factor 7-Like 1 Protein|Transcription Factors|Trans-Activators|HMGB Proteins|Repressor Proteins|Xenopus Proteins|Protein Binding|Binding Sites|Protein Conformation|Amino Acid Sequence|Crystallography, X-Ray|Cadherins|Signal Transduction|Transcription Factor 7-Like 2 Protein | |
11136978 Cell 2001 *Phosphoinositide 3 Kinase|*Phosphatidylinositol 3-Kinases|PIK3CG protein, human|Class Ib Phosphatidylinositol 3-Kinase|Protein Conformation|ras Proteins|Protein Binding|PIK3CA protein, human|Class I Phosphatidylinositol 3-Kinases|Signal Transduction|Binding Sites|GTPgammaS|Models, Molecular|Catalytic Domain | |
11136979 Cell 2001 *Receptors, EphB|*Receptors, N-Methyl-D-Aspartate|Synapses|Neurons|Ephrin-B1|Receptors, Glutamate|Glutamate|Ephrin-B2|Phosphorylation|Receptor, EphB4|Signal Transduction|*Neurogenesis|Membrane Proteins|Cerebral Cortex | |
11137016 Curr. Biol. 2001 Animals|CTNNB1 protein, human|*beta Catenin|*Wnt Signaling Pathway|Xenopus laevis|Wnt Proteins|Xenopus Proteins|Low Density Lipoprotein Receptor-Related Protein-6|Frizzled Receptors|Zebrafish Proteins|Trans-Activators|Intercellular Signaling Peptides and Proteins|Embryo, Nonmammalian|Proto-Oncogene Proteins|Protein Binding|Amino Acid Sequence|Receptors, LDL|Gene Expression Regulation, Developmental|Dkk2 protein, Xenopus | |
11138003 Nat. Genet. 2001 PMC1350991 Humans|*Cholesterol, Dietary|gamma-sitosterol|Sitosterols|ATP Binding Cassette Transporter, Subfamily G, Member 8|ATP Binding Cassette Transporter, Subfamily G, Member 5|Sitosterolemia|Lipid Metabolism, Inborn Errors|Plant Sterol|Cholesterol|ATP-Binding Cassette Transporters|Lipoproteins|Intestinal Absorption|Amino Acid Sequence|*Diet|Mutation|Hypercholesterolemia|ABCG5 protein, human | |
11139380 Biochem. J. 2001 PMC1221558 *Retinoid X Receptor alpha|*Peroxisome Proliferator-Activated Receptor gamma|*B-DNA|*Peroxisomes|DNA-Binding Proteins|Retinoid X Receptors|DNA Sequence|Binding Sites|Transcription, Genetic|*Dimerization|Receptors, Steroid|Transfection|Promoter Regions, Genetic|Response Element|Gel Shift Analysis|Ligands | |
11139407 Biochem. J. 2001 PMC1221585 Rats|Animals|*Superoxides|*Electron Transport|*Mitochondrial Membranes|*Mitochondria|superoxide dismutase 2|Mn-Superoxide Dismutase|Hydrogen Peroxide|Oxidation-Reduction|antimycin|Antimycin A|Mitochondria, Liver|Oxidants|Cytochrome c|Rats, Wistar|Rotenone|Digitonin|Cytosol | |
11139587 J. Biol. Chem. 2001 Humans|*Adaptor Protein Complex 4|Adaptor Protein Complex 1|Integral Membrane Proteins|Adaptor Protein Complex 2|Adaptor Proteins, Vesicular Transport|Adaptor Protein Complex alpha Subunits|Clathrin|Monomeric Clathrin Assembly Proteins|Membrane Glycoproteins|Plasma Membrane|Lysosomes|Nerve Tissue Proteins|Amino Acid Sequence|Lysosome-Associated Membrane Glycoproteins|Protein Transport | |
11139592 J. Biol. Chem. 2001 Humans|N-acetylgalactosamine-4-sulfotransferase|*Acetylgalactosamine|HNK-1 sulfotransferase|*Sulfotransferases|CHST11 protein, human|*Cloning, Molecular|Amino Acid Sequence|cDNA|Base Sequence|*Sulfates|Sequence Alignment|Open Reading Frame|Chromosome Mapping|Exons|Sequence Homology, Amino Acid|Blotting, Northern|*Sulfur Oxides|Substrate Specificity | |
11139606 Nucleic Acids Res. 2001 PMC29666 Humans|RPA1 protein, human|*Replication Protein A|*DNA|DNA Replication|Single-Stranded DNA-Binding Protein|DNA, Single-Stranded|Templates, Genetic|Oligonucleotides|Nucleotide Excision Repair|DNA Primers|Photoaffinity Labels|Nucleotides|Cross-Linking Reagents|Azides | |
11139613 Nucleic Acids Res. 2001 PMC29662 Humans|APEX1 protein, human|*AP Lyase|8-hydroxyguanine|oxoguanine glycosylase 1, human|*DNA Glycosylases|*Base Excision Repair|DNA-Formamidopyrimidine Glycosylase|Guanine|Deoxyribonuclease IV (Phage T4-Induced)|Escherichia coli Proteins|DNA|Substrate Specificity|Escherichia coli|Kinetics|Carbon-Oxygen Lyases|Mutagenesis|Oligonucleotides|Endonucleases | |
11139615 Nucleic Acids Res. 2001 PMC29672 Humans|deoxyguanosine triphosphate|Deoxyguanine Nucleotides|8-oxodGTPase|*Phosphoric Monoester Hydrolases|8-hydroxy-2'-deoxyguanosine 5'-triphosphate|*DNA Repair Enzymes|*Hydrolysis|*Oxidation-Reduction|2'-deoxyadenosine triphosphate|Deoxyadenine Nucleotides|2',3'-dialdehyde ATP|Adenosine Triphosphate|8-hydroxyadenosine 5'-triphosphate|Escherichia coli Proteins|Pyrophosphatases|*Ribonucleotides|Substrate Specificity|8-hydroxyguanosine triphosphate | |
11140638 Nature 2001 Caspases|Protein, Mitochondrial|Protein Binding|X-Linked Inhibitor of Apoptosis Protein|Apoptosis|Caspase Inhibitors|Inhibitor of Apoptosis Proteins|Caspase 9|Carrier Proteins|Intracellular Signaling Peptides and Proteins|Amino Acid Sequence|*Cell Death|Caspase 3|rpr protein, Drosophila|Drosophila Proteins|prolylvaline|Dipeptides | |
11141066 Biochemistry 2001 *Transcription Factor IIH|*Nucleotide Excision Repair|Endonucleases|DNA Helicases|*DNA|DNA Damage|Xeroderma Pigmentosum Group A Protein|Transcription Factors|Xeroderma Pigmentosum Group D Protein|Nuclear Proteins|RNA Polymerase II|ATPase|Nucleotides | |
11141079 Biochemistry 2001 Rab geranylgeranyl transferase beta-subunit|*Allosteric Regulation|geranylgeranyl pyrophosphate|Polyisoprenyl Phosphates|*Transferases|Protein Prenylation|Alkyl and Aryl Transferases|rab GTP-Binding Proteins|Protein Binding|Substrate Specificity|Kinetics|Adaptor Proteins, Signal Transducing|Binding Site | |
11145705 J. Immunol. 2001 Mice|Animals|*Neutrophils|*NADP|*Neutrophil Activation|*NADPH Oxidase|N-Formylmethionine Leucyl-Phenylalanine|*Signal Transduction|MAPK3 protein, human|Extracellular Signal Regulated Kinase 1|Mitogen-Activated Protein Kinases|Superoxide|rac GTP-Binding Proteins|*Oxidation-Reduction|Enzyme Activation|rac1 GTP-Binding Protein|Phagocytosis|Phosphorylation|Zymosan|SB 203580 | |
11145836 Cytokine 2001 Humans|Male|Female|Animals|IL-1H receptor|Leukocytes, Mononuclear|*Receptors, Interleukin|Amino Acid Sequence|interleukin 18 protein, human|Interferon-gamma-Inducing Factor|Cell Line|Base Sequence|Receptor, IL-18|Cloning, Molecular|*Receptors, Cytokine|RNA, Messenger|Cytokines|Sequence Homology, Amino Acid|Protein Binding|Interleukin-1 | |
11145955 J. Biol. Chem. 2001 Humans|Animals|Cricetinae|*Serum Response Element|*Phosphorylation|*MCF-7 Cells|CHO Cells|Cricetulus|*Mitogen-Activated Protein Kinases|ets-Domain Protein Elk-1|Transcription Factors|estrogen receptor alpha, human|Estrogen Receptor alpha|Activation, Transcriptional|*Signal Transduction|c-fos Proto-Oncogene|Mitogen-Activated Protein Kinase 3|Mitogen-Activated Protein Kinase 1|Proto-Oncogene Proteins|Serum Response Factor|Promoter Regions, Genetic | |
11146548 Oncogene 2001 Humans|BCAR1 protein, human|*Crk-Associated Substrate Protein|*Signal Transduction|PXN protein, human|Paxillin|PTK2 protein, human|Focal Adhesion Kinase 1|GAB1 protein, human|*Adaptor Proteins, Signal Transducing|CRK protein, human|Proto-Oncogene Proteins c-crk|Focal Adhesion Kinase|Phosphorylation|Focal Adhesions|Cytoskeletal Proteins|*Oncogene Proteins|Tyrosine|*Cell Transformation, Neoplastic | |
11146634 Nat. Cell Biol. 2001 CFTR protein, human|*Cystic Fibrosis Transmembrane Conductance Regulator|*Molecular Chaperones|Endoplasmic Reticulum|HSC70 Heat-Shock Proteins|HSP70 Heat-Shock Proteins|Protein Folding|Proteasome Endopeptidase Complex|Ubiquitin|Ubiquitins|Carrier Proteins|Ubiquitination|Cystic Fibrosis|Ubiquitin-Protein Ligases|Protein Transport|Cysteine Endopeptidases | |
11146656 Nat. Cell Biol. 2001 Humans|*Septins|*AAA Domain|*Mitochondria|*Apoptosis|CASP3 protein, human|Caspase 3|Amino Acid Sequence|Cell Nucleus | |
11147812 J. Cell. Physiol. 2001 Mice|Animals|*Receptor, trkA|IRS2 protein, human|*Insulin Receptor Substrate Proteins|GRB2 protein, human|GRB2 Adaptor Protein|PTPN11 protein, human|Protein Tyrosine Phosphatase, Non-Receptor Type 11|Signal Transduction|Phosphorylation|Phosphoproteins|Tyrosine|NGFR protein, human|Nerve Tissue Proteins|Protein Tyrosine Phosphatase, Non-Receptor Type 6|Phosphatidylinositol 3-Kinases|Amino Acid Sequence|Protein Binding|Receptors, Nerve Growth Factor | |
11149895 FASEB J. 2001 Cricetinae|Animals|NOS3 protein, human|*Nitric Oxide Synthase Type III|Endothelial Cells|Cricetulus|CAV1 protein, human|Caveolin 1|Nitric Oxide Synthase|Membrane Proteins|Nitric Oxide|Calmodulin|Endothelium, Vascular|Carrier Proteins|Amino Acid Sequence|Plasma Membrane|Acylation|Cytoplasm|*Oxidation-Reduction|Cells, Cultured | |
11149950 Proc. Natl. Acad. Sci. U.S.A. 2001 PMC14617 Humans|Mice|Animals|ABCA1 protein, human|ATP Binding Cassette Transporter 1|Orphan Nuclear Receptors|ApoE protein, human|Apolipoproteins E|ABCG1 protein, human|ATP Binding Cassette Transporter, Subfamily G, Member 1|Liver X Receptors|*Macrophages|*Adipocytes|Receptors, Retinoic Acid|Atherosclerosis|Retinoid X Receptors|Gene Expression Regulation|Macrophages, Peritoneal|Hydrocarbons, Fluorinated|ATP-Binding Cassette Transporters|Mice, Knockout | |
11152476 J. Biol. Chem. 2001 Humans|Animals|Rats|*Syntenins|NRXN1 protein, human|Cell Adhesion Molecules, Neuronal|Membrane Proteins|Binding Protein|NRCAM protein, human|Cell Adhesion Molecules|Nerve Tissue Proteins|Intracellular Signaling Peptides and Proteins|Isoforms|Membrane Glycoproteins|Amino Acid Sequence|Cell Membrane|Binding Sites|Cytoplasm|Protein Transport|Cell Movement|Ligands | |
11153648 Vis. Neurosci. 2001 PMC1410813 retinol dehydrogenase|*Loss of Function Mutation|*Retinal Cone Photoreceptor Cells|*Alcohol Oxidoreductases|Dark Adaptation|Retinal Rod Photoreceptor Cells|11-cis-Retinal|Retina|Retinal Degeneration|Fundus Albipunctatus|11-cis-Retinol|Vision|Retinal Pigment Epithelium | |
11154734 Chem. Biol. Interact. 2001 Animals|leukotriene A4 hydrolase|*Epoxide Hydrolases|Epoxides|Microsomes, Liver|Xenobiotics|Cytochrome P-450 Monooxygenase|*Molecular Biology|trans-1,2-dihydro-1,2-naphthalenediol|Naphthalenes|*Biochemical Phenomena|Catalysis|Oxidation-Reduction | |
11154739 Chem. Biol. Interact. 2001 Humans|*Sulfotransferases|*Xenobiotics|Mutagenicity Tests|Mutagens|Carcinogens|Biotransformation|Genetic Polymorphisms|Cytosol|Hydroxylations|Inactivation, Metabolic|Salmonella typhimurium|Sulfuric Acid Esters|Substrate Specificity | |
11156414 Cancer Res. 2001 *Carbonic Anhydrases|Vascular Endothelial Growth Factor A|VHL protein, human|Von Hippel-Lindau Tumor Suppressor Protein|Renal Cell Carcinoma|Transcription Factors|Kidney Neoplasms|Nuclear Proteins|CA9 protein, human|Carbonic Anhydrase IX|*Hypoxia|Vascular Endothelial Growth Factors|Trans-Activators|Basic Helix-Loop-Helix Transcription Factors|Genes, Tumor Suppressor|Up-Regulation|Antigens, Neoplasm|Gene Expression Regulation, Neoplastic | |
11156536 Am. J. Hum. Genet. 2001 PMC1235268 Humans|Child|phosphomannomutase|Congenital disorder of glycosylation type 1A|*Congenital Disorders of Glycosylation|*Phosphotransferases (Phosphomutases)|Phenotype|Mutation|Glycosylation|*Fibroblasts|Cerebellar Hypoplasia|Cerebellum|Intellectual Disability|Developmental Disabilities | |
11156592 Br. J. Pharmacol. 2001 PMC1572546 Animals|Cricetinae|Humans|*Adenylyl Cyclases|*Phospholipase C|CHO Cells|Cricetulus|Cyclic AMP|Second Messenger|Inositol Phosphates|Receptors, Purinergic P2|Tumor Cells, Cultured|Astrocytoma | |
11157096 J. Neurosci. 2001 PMC6762309 Humans|*Receptors, Neurotrophin|*Cytoplasmic Dyneins|tropomyosin-related kinase-B, human|Receptor, trkB|Dynein|NGF protein, human|Nerve Growth Factor|Receptor, trkA|trkC Receptor|Neurons|Signal Transduction|Transfection|Cell Membrane|Cytoplasm|Protein Transport|Protein Binding|Membrane Glycoproteins | |
11157473 Blood 2001 P2 Receptors, Purinergic|Adenosine Diphosphate|*Blood Cells|Adenosine Triphosphate|Signal Transduction|Cell Differentiation|Platelets|Chemotaxis|Leukocytes | |
11157485 Blood 2001 Humans|*Factor VIIIa|*Thrombin|*Hemophilia A|F8 protein, human|Factor VIII|*Hemophilia B|*Mutations|Blood Coagulation|Phenotype|Protein Binding|Kinetics|Protein Subunits|Factor IX | |
11157491 Blood 2001 Humans|Mice|Animals|Thanatophoric Dysplasia, Type I|FGFR3 protein, human|*Receptor, Fibroblast Growth Factor, Type 3|*Multiple Myeloma|Mice, Nude|*Oncogene|Translocation, Genetic|Mutations|Signal Transduction|Cell Transformation, Neoplastic|Gene Expression Regulation, Neoplastic|Thanatophoric Dysplasia|NSD2 protein, human|Repressor Proteins|*Neoplastic Processes|Histone-Lysine N-Methyltransferase|Tumor Microenvironment | |
11157743 EMBO J. 2001 PMC133459 *Influenza B virus|*Interferon|INS1 protein, influenza virus|*Viral Nonstructural Proteins|*Antiviral Agents|Ubiquitins|Interferon-beta|Influenza A virus|Cytokines|TYRP1 protein, human|Protein Binding|*Membrane Glycoproteins|Amino Acid Sequence | |
11157749 EMBO J. 2001 PMC133464 *Phosphorylation|Transcription Factors|*G1 Phase|Cell Cycle|Phosphoproteins|CDK2 protein, human|Cyclin-Dependent Kinase 2|Cyclin|Retinoblastoma-Like Protein p130|Retinoblastoma Protein|E2F Transcription Factors|CDK4 protein, human|Cyclin-Dependent Kinase 4|Cyclin-Dependent Kinases|Carrier Proteins|Retinoblastoma-Like Protein p107|Transcription Factor DP1|Retinoblastoma-Binding Protein 1 | |
11157794 Hum. Mol. Genet. 2001 Humans|*Cystinuria|HeLa Cells|Amino Acid Transport Systems, Basic|*Mutations|Heterozygotes|Mutations, Missense|*Genotype-Phenotype Correlation|Exons|Membrane Glycoproteins|Cystine|Phenotype|Carrier Proteins|Alleles|Amino Acids|SLC7A9 protein, human|SLC3A1 protein, human|Amino Acid Transport Systems, Neutral | |
11157804 Hum. Mol. Genet. 2001 Humans|Mice|Animals|*Charcot-Marie-Tooth Disease|periaxin|*CMT4f|*Membrane Proteins|*Mutation|Genes, Recessive|Myelin Sheath|Pedigree|Demyelinating Diseases | |
11157975 J. Cell Biol. 2001 PMC2196001 *Arp2-3 Complex|*Binding Protein|*Wiskott-Aldrich Syndrome Protein|WASL protein, human|*Wiskott-Aldrich Syndrome Protein, Neuronal|Actin-Related Protein 3|Actin-Related Protein 2|Actins|SH3 Domain|GRB2 protein, human|GRB2 Adaptor Protein|Nerve Tissue Proteins|cdc42 GTP-Binding Protein|Wiskott-Aldrich Syndrome|Phosphatidylinositol 4,5-Diphosphate|Protein Binding|Signal Transduction | |
11157984 J. Cell Biol. 2001 PMC2195994 Mice|Animals|*Actins|INSR protein, human|*Receptor, Insulin|*Actin Cytoskeleton|cdc42 GTP-Binding Protein|Filopodia|*Neurite Outgrowth|BAIAP2 protein, human|Nerve Tissue Proteins|Cytoskeleton|rac GTP-Binding Proteins|rac1 GTP-Binding Protein|*Antigens, CD|Neurites|Cell Cycle Proteins|Fibers, Stress|Adaptor Proteins, Signal Transducing|SH3 Domain | |
11158055 J. Clin. Endocrinol. Metab. 2001 Male|Rats|Humans|Mice|Animals|*3-alpha-Hydroxysteroid Dehydrogenase (B-Specific)|*Tissue Distribution|HEK293 Cells|3-Hydroxysteroid Dehydrogenases|Amino Acid Sequence|Transfection|Base Sequence|Kidney|Testis|Cloning, Molecular|Steroids|Prostate|Dihydrotestosterone|Multienzyme Complexes|Liver | |
11158056 J. Clin. Endocrinol. Metab. 2001 Pregnancy|Female|Humans|*Insulin-Like Growth Factor Binding Protein 4|*Pregnancy-Associated Plasma Protein-A|*Proteolysis|IGF2 protein, human|Insulin-Like Growth Factor II|IGFBP5 protein, human|Insulin-Like Growth Factor Binding Protein 5|*Protein Binding|IGFBP3 protein, human|Insulin-Like Growth Factor Binding Protein 3|Metalloendopeptidases|Osteoblasts|Cells, Cultured|Blood Proteins|Antibodies|Molecular Weight|*Signal Transduction|Fibroblasts | |
11158290 Mol. Cell. Biol. 2001 PMC99557 IKBKE protein, human|*I-kappa B Kinase|NFKBIA protein, human|*NF-KappaB Inhibitor alpha|*NF-kappa B|*beta-Transducin Repeat-Containing Proteins|I-kappa B Proteins|RELA protein, human|*Transcription Factor RelA|Phosphorylation|NF kappa B p50 Subunit|Signal Transduction|*Ubiquitination|Ubiquitin Ligase, SCF|Ubiquitins|DNA-Binding Proteins|Protein Processing, Post-Translational|Protein Precursors | |
11158296 Mol. Cell. Biol. 2001 PMC99563 Humans|*Saccharomyces cerevisiae|*Coenzyme A|*Mitochondria|Saccharomyces cerevisiae Proteins|Carrier Proteins|Membrane Transport Proteins|Mitochondrial Proteins|Mitochondrial Membrane Transport Proteins|Biological Transport|*Yeast, Dried|Membrane Proteins|Mitochondrial Membranes|Amino Acid Sequence|*Graves Disease | |
11158580 Proc. Natl. Acad. Sci. U.S.A. 2001 PMC14694 *E3 Ubiquitin Ligase|SMAD2 protein, human|Smad2 Protein|Smad Proteins|Transforming Growth Factor beta|Bone Morphogenetic Protein|SMAD3 protein, human|Smad3 Protein|Trans-Activators|Smad1 Protein|Signal Transduction|Ubiquitin|Transcription, Genetic|Protein Binding | |
11158588 Proc. Natl. Acad. Sci. U.S.A. 2001 PMC14702 Humans|Mice|Animals|*Endostatins|*Integrins|Endothelial Cells|Collagen XVIII|*Neovascularization, Pathologic|Cell Migration|Cell Adhesion|Collagen|Signal Transduction|Angiogenesis Inhibitors|Endothelium, Vascular|Peptide Fragments|*Morphogenesis | |
11159893 Gastroenterology 2001 Animals|Humans|*Organic Anion Transporters|*Liver|Hepatocytes|Estrone|Biological Transport|Xenopus laevis|Carrier Proteins|Oocytes|Substrate Specificity|Peptides|Anions | |
11160214 J. Immunol. 2001 *Calnexin|*Histocompatibility Antigens Class I|*Genes, MHC Class I|tapasin|Membrane Transport Proteins|calreticulin, human|Calreticulin|*Molecular Chaperones|*Endoplasmic Reticulum|PDIA3 protein, human|Protein Disulfide-Isomerases|ATP Binding Cassette Transporter, Subfamily B, Member 2|ATP Binding Cassette Transporter, Subfamily B, Member 3|Antiporters|ATP-Binding Cassette Transporters|Calcium-Binding Proteins|Antigen Presentation|beta 2 Microglobulin | |
11160393 J. Neurosci. 2001 PMC6762235 NR1 NMDA receptor|NR3A NMDA receptor|*Receptors, N-Methyl-D-Aspartate|Protein Transport|Endoplasmic Reticulum|Protein Subunits|Plasma Membrane|Cell Line | |
11160719 J. Virol. 2001 PMC114799 Humans|*HIV-1|*p21-Activated Kinases|nef Gene Products, Human Immunodeficiency Virus|*Rho Guanine Nucleotide Exchange Factors|Phosphorylation|Cell Line|PAK2 protein, human|nef protein, Human immunodeficiency virus 2|nef protein, Human immunodeficiency virus 1 | |
11160876 Mol. Pharmacol. 2001 Male|Humans|*Cytochrome P-450 CYP3A|*DNA, Complementary|*Cytochrome P450|Aryl Hydrocarbon Hydroxylases|Amino Acid Sequence|Liver|Cloning, Molecular|Base Sequence|Intron|Gene Expression|Exon|RNA, Messenger|Immunoblotting | |
11160897 Nucleic Acids Res. 2001 PMC30391 Humans|Mice|Animals|*Endonuclease, Apurinic|*Adenine|mutY adenine glycosylase|*DNA Glycosylase|adenine glycosylase|*Base Excision Repair|Deoxyribonuclease IV (Phage T4-Induced)|DNA-Formamidopyrimidine Glycosylase|*DNA|Escherichia coli Proteins|Escherichia coli|8-hydroxyguanine|Guanine|Base Pair Mismatch|Carbon-Oxygen Lyases|DNA Damage|Kinetics|Amino Acid Sequence | |
11160957 Neurology 2001 Humans|Mice|Animals|*Coffin-Lowry Syndrome|ribosomal protein S6 kinase, 90kDa, polypeptide 3|Ribosomal Protein S6 Kinases, 90-kDa|Intellectual Disability|cAMP Response Element Binding Protein|Abnormalities, Multiple|Phosphorylation|Mutations|X Chromosome|Epidermal Growth Factor|Serine|*Cognitive Impairment | |
11161786 Genomics 2001 Animals|Humans|*DNA, Complementary|*Sodium Sulfate Cotransporter|Base Sequence|Symporters|Chromosome Mapping|Amino Acid Sequence|*Kidney|Cloning, Molecular|Exons|Xenopus laevis|Sodium|Oocytes|RNA, Messenger|Sulfate Transporters | |
11162494 Biochem. Biophys. Res. Commun. 2001 Humans|Mice|Animals|Rats|*Basic Helix-Loop-Helix Transcription Factors|Transcription Factors|Helix-Loop-Helix Motifs|Homeodomain Proteins|*Cloning, Molecular|Amino Acid Sequence|Sequence Alignment|Sequence Homology, Amino Acid|Drosophila|RNA, Messenger|Cell Differentiation | |
11162552 Biochem. Biophys. Res. Commun. 2001 Chlorocebus aethiops|Animals|*Protein Binding|Carrier Proteins|Amino Acid Sequence|rho GTP-Binding Proteins|Membrane Proteins|Signal Transduction|cdc42 GTP-Binding Protein|Binding Sites|Sequence Homology, Amino Acid|Two-Hybrid System Techniques|Protein Conformation|COS Cells|*Protein Domains | |
11162607 Biochem. Biophys. Res. Commun. 2001 Humans|*DNA, Complementary|*Cytochrome P450|Aryl Hydrocarbon Hydroxylases|*Oxidation-Reduction|Blotting, Northern|Cloning, Molecular|Base Sequence|Amino Acid Sequence|PGH(2)|Omega-Hydroxylase|Exons|Liver|Eicosanoids|Kidney|Arachidonic Acid|CYP4F12 protein, human|CYP4F11 protein, human|Cytochrome P450 Family 4 | |
11162936 J. Steroid Biochem. Mol. Biol. 2001 *Ligands|*Estrogens|Estrogen Antagonists|Receptors, Estrogen|afimoxifene|Tamoxifen|ERbeta|ERalpha|Antiestrogen|Raloxifene|Selective Estrogen Receptor Modulators|Estradiol|Response Element|Transcription, Genetic|Promoter Regions, Genetic|Quinone Reductase|Protein Binding|Structure-Activity Relationship | |
11163197 Immunity 2001 *Tyrosine Kinase|*Phosphatidylinositol 3-Kinases|*Phosphorylation|*Receptors, Antigen, B-Cell|Adaptor Proteins, Signal Transducing|B-Lymphocytes|Syk Kinase|Intracellular Signaling Peptides and Proteins|src-Family Kinases|Phosphoproteins|Phospholipase C gamma|Agammaglobulinaemia Tyrosine Kinase|Carrier Proteins|Signal Transduction|Enzyme Activation|Enzyme Precursors | |
11163199 Immunity 2001 *MHC Class I Molecules|Endoplasmic Reticulum|Antigen Presentation|Golgi Apparatus|Membrane Transport Proteins|Carrier Proteins|Protein Transport|Membrane Proteins|Peptides | |
11163209 Mol. Cell 2001 Cricetinae|Animals|*Proteases|membrane-bound transcription factor peptidase, site 1|Proprotein Convertases|Serine Endopeptidases|Golgi Apparatus|Activating Transcription Factor 6|Endoplasmic Reticulum|Cell Nucleus|Membrane Proteins|*Endoplasmic Reticulum Stress|Protein Binding|Molecular Chaperones|Sterol Regulatory Element Binding Protein 1|CHO Cells | |
11163210 Mol. Cell 2001 *E3 Ubiquitin Ligase|*Receptors, Transforming Growth Factor beta|SMAD7 protein, human|*Smad7 Protein|TGFBR2 protein, human|*Receptor, Transforming Growth Factor-beta Type II|UBB protein, human|Ubiquitin|Signal Transduction|Transforming Growth Factor beta|Protein Binding|Proteasome|Smad2 Protein|Trans-Activators|Protein-Serine-Threonine Kinases|DNA-Binding Proteins|Receptor, Transforming Growth Factor-beta Type I|Activin Receptors, Type I | |
11163236 Cell 2001 Mice|Animals|interleukin 20|*Interleukin|*Epidermis|Keratinocyte|interleukin-20 receptor|Receptors, Interleukin|Psoriasis|IL10 protein, human|IL10|STAT3 protein, human|STAT3 Transcription Factor|Skin|*Carrier Proteins|Cell Differentiation|Signal Transduction Pathway|Cytokines|Cytokine Receptor|Cells, Cultured | |
11163244 Cell 2001 Animals|Cricetinae|Humans|XRCC1 protein, human|*X-ray Repair Cross Complementing Protein 1|*Polynucleotide 5'-Hydroxyl-Kinase|*DNA Repair|*DNA Breaks, Single-Stranded|*DNA Damage|Pol beta protein, human|DNA Polymerase beta|LIG3 protein, human|DNA Ligase III|*DNA|Poly-ADP-Ribose Binding Proteins|DNA Ligases|*Phosphorylation|DNA-Binding Proteins|DNA, Single-Stranded|DNA Replication|Ionizing Radiation | |
11163539 Free Radic. Biol. Med. 2001 Humans|*MAPK, p38|*Peroxynitrous Acid|*Neuroblastoma|Mitogen-Activated Protein Kinases|Phosphorylation|4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole|Imidazoles|Pyridines|Transcription Factors|Signal Transduction|Transcription Factor CHOP|Apoptosis|Tumor Cells, Cultured|Glutathione | |
11165043 Mol. Cell. Endocrinol. 2001 Humans|AHR protein, human|*Receptors, Aryl Hydrocarbon|*Transcriptional Activation|*Cathepsin D|*Estradiol|estrogen receptor alpha, human|ERalpha|Tetrachlorodibenzo-p-dioxin|*Basic Helix-Loop-Helix Transcription Factors|Receptors, Estrogen|Promoter Regions, Genetic|*Gene Expression|Estrogens|Dioxins|DNA Footprinting | |
11165242 FEBS Lett. 2001 Cricetinae|Animals|Humans|*Circadian Clock Protein Period 1|*Casein Kinase Idelta|*Phosphorylation|*Circadian Clocks|Suprachiasmatic Nuclei|Casein Kinase Iepsilon|CLOCK Proteins|Circadian Rhythm|Nuclear Proteins|Cell Cycle Proteins|Protein Kinases|Binding Sites|Protein Binding|Protein Processing, Post-Translational|Cell Line | |
11169766 Cell Motil. Cytoskeleton 2001 *Chondrocytes|exostosin-1|*N-Acetylglucosaminyltransferases|Multiple Exostoses|*Exostosis|*Osteochondroma|DNA Mutational Analysis|Mutations|Loss of Heterozygosity|Chondrosarcomas|Actin|Intron|Cytoskeleton|Bone Neoplasms|Tumor Suppressor Proteins | |
11171088 Biochem. J. 2001 PMC1221637 Humans|Mice|Animals|*Monophenol Monooxygenase|5,6-dihydroxy-2-indolylcarboxylic acid|Indoles|eumelanin|Melanins|TYRP1 protein, human|*Oxidoreductases|tyrosinase-related protein-1|indole|Melanocytes|melanogen|Membrane Glycoproteins|L Tyrosine|dopaquinone|Dihydroxyphenylalanine|Oxidation-Reduction|Intramolecular Oxidoreductases|Cell Line | |
11171096 Biochem. J. 2001 PMC1221645 *Mycobacterium tuberculosis|Isoniazid|Antitubercular Agents|Catalase|Peroxiredoxins|Genes, Bacterial|Bacterial Proteins|Oxidative Stress|Oxidation-Reduction|Peroxides | |
11171333 Development 2001 Mice|Animals|NOTCH2 protein, human|*Receptor, Notch2|*Homozygote|*Heart|Serrate-Jagged Proteins|Jagged-1 Protein|*Mutation|Alagille Syndrome|Receptors, Notch|Intercellular Signaling Peptides and Proteins|Calcium-Binding Proteins|*Kidney|Membrane Proteins|Signal Transduction Pathway|Morphogenesis|Myocardium|Cell Differentiation|Heterozygote | |
11171374 J. Cell. Sci. 2001 Male|Animals|*Cyclin-Dependent Kinases|*Meiosis|Cyclins|CDK2 protein, human|Cyclin-Dependent Kinase 2|Spermatocytes|Mitosis|Cyclin-Dependent Kinase 4|Synapsis|Synaptinemal Complex|Retinoblastoma Protein|G1 Phase|Replication Protein A|Microtubule-Associated Proteins|Cyclin-Dependent Kinase Inhibitor p27 | |
11171983 Proc. Natl. Acad. Sci. U.S.A. 2001 PMC29289 Animals|*E2F6 Transcription Factor|*Polycomb-Group Proteins|BMI1 protein, human|*Polycomb Repressive Complex 1|DNA-Binding Proteins|Cell Cycle|Promoter Regions, Genetic|*Drosophila Proteins | |
11172815 FEBS Lett. 2001 Animals|Humans|*GTPase-Activating Proteins|ADP-Ribosylation Factors|ADP-Ribosylation Factor 1|Guanosine Triphosphate|Protein Transport|Cell Line|Phosphatidylinositol|Phospholipids|Phosphatidyl Choline | |
11175906 Nat. Struct. Biol. 2001 Humans|*Ferrochelatase|protoporphyrin IX|Protoporphyrins|Haem|Iron-Sulfur Proteins|Iron|Binding Sites|Crystallography, X-Ray|*Biochemical Phenomena|Models, Molecular|Dimerization|Catalysis | |
11178875 Mol. Cell. Neurosci. 2001 postsynaptic density proteins|sharpin|Shank1 protein, rat|*Nerve Tissue Proteins|Synapses|Carrier Proteins|Adaptor Proteins, Signal Transducing|Neurons|SH3 Domain|Protein Binding|Hippocampus|Two-Hybrid System Techniques|Amino Acid Sequence|Brain|Ankyrin Repeat|Sequence Homology, Amino Acid | |
11178988 Biochem. Biophys. Res. Commun. 2001 Humans|*ATP-Binding Cassette Transporters|*Macrophages|*Open Reading Frames|ABCA1 protein, human|ATP Binding Cassette Transporter 1|*Sterols|Exons|cDNA|Cholesterol|Introns|Monocytes|mRNA|Amino Acid Sequence|Cloning, Molecular|Promoter Regions, Genetic|Genomics | |
11179213 EMBO J. 2001 PMC145419 Humans|lysosomal proteins|*Lysosomes|Endosomes|rab GTP-Binding Proteins|Adaptor Proteins, Signal Transducing|Protein Binding|Protein Transport|Endocytosis|Amino Acid Sequence|HeLa Cells|Epidermal Growth Factor|RILP protein, human | |
11179430 Mol. Biol. Cell 2001 PMC30958 Cricetinae|Animals|Humans|*Dolichol|Dolichol Monophosphate Mannose|Glycosylphosphatidylinositols|Mannosyltransferases|*Glycosyltransferases|Glycosylation|Mannose|mannose-phosphate-citronellol|Glycolipids|*Monosaccharides|Endoplasmic Reticulum|CHO Cells|Amino Acid Sequence|*Mammals|lipid-linked oligosaccharides|Lipopolysaccharides|Monoterpenes | |
11179879 Curr. Opin. Neurobiol. 2001 *Growth Cones|*rho GTPases|Actin|Axons|Actin Cytoskeleton|Neurons|Cell Movement|Signal Transduction | |
11181075 Biochem. Biophys. Res. Commun. 2001 *TNF Receptor-Associated Factor 2|*TNF Receptor-Associated Factor 1|*Caspases|*Apoptosis|CASP8 protein, human|Caspase-8|Tumor Necrosis Factor Receptor|*Cell Death|Receptors, Tumor Necrosis Factor, Type I|NF-kappa B|Signal Transduction|Tumor Necrosis Factor-alpha | |
11181178 J. Cell. Sci. 2001 Humans|Animals|*Nuclear Pore|*M Phase Cell Cycle Checkpoints|*Cell Cycle Proteins|Kinetochores|Mitosis|Mad2 Proteins|Spindle Apparatus|Nuclear Proteins|Phosphoproteins|SMAD2 protein, human|*Smad2 Protein|Cell Cycle|Repressor Proteins|Anaphase|Calcium-Binding Proteins|TYRP1 protein, human|*Membrane Glycoproteins|Fungal Proteins | |
11181538 Endocrinology 2001 Rats|Animals|*Insulin Secretion|*Protein Kinase A|*Phosphorylation|AKT1 protein, human|*Protein Kinase B|Insulin|Islets of Langerhans|Cyclic AMP|Forskolin|Glucose|Signal Transduction|Synapsin I | |
11181649 J. Clin. Invest. 2001 PMC199271 Infant, Newborn|Adult|Humans|3-methylcrotonyl CoA carboxylase 1 deficiency|*Carbon-Carbon Ligases|*Urea Cycle Disorders, Inborn|DNA Mutational Analysis|Alleles|Exons|Mutations|*Maple Syrup Urine Disease|cDNA|Phenotype|Sequence Analysis, DNA|Mutations, Missense|Neonatal Screening|Amino Acid Sequence|Biotin|*Databases, Genetic | |
11181758 J. Lipid Res. 2001 Humans|*Chylomicrons|*Esters|Caco-2 Cells|Lipoproteins|Vitamin A|Retinoids|Biological Transport|Dietary Supplements|*Intestine|Apolipoproteins B | |
11182090 Neuron 2001 Mice|Animals|*Synaptic Vesicles|*Channel, Chloride|*Hippocampus|Excitatory Postsynaptic Currents|Neurons|Chlorides|Mice, Knockout | |
11182528 Free Radic. Biol. Med. 2001 *Hypochlorous Acid|chloramine|*Chloramines|*Methionine|*Kinetics|*Racemethionine|Oxidants|thionitrobenzoic acid|*Thiols|Oxidation-Reduction|*Ascorbic Acid|Glutathione, Reduced|Cysteine|*Amino Acids|Glycine|N-chlorotaurine|Taurine|N(alpha)-acetyllysine | |
11185745 J. Hum. Genet. 2001 Humans|*Holocarboxylase Synthetase Deficiency|*Haplotypes|Japan|*Mutations|Alleles|Genotype|Heterozygote|Carbon-Nitrogen Ligases|Base Sequence|Biotin | |
11185956 IUBMB Life 2001 Animals|Rats|sphingosine 1-phosphate|MAPK3 protein, human|*Mitogen-Activated Protein Kinase 3|*Lysophospholipids|*Sphingosine|EGFR protein, human|*Epidermal Growth Factor Receptor|Mitogen-Activated Protein Kinase 1|Mitogen-Activated Protein Kinases|RTKI cpd|Tyrphostins|Phosphorylation|Quinazolines|MAP2K1 protein, human|MAP Kinase Kinase 1|MAP Kinase Signaling System|Signal Transduction|Protein Kinase C | |
11187898 Leukemia 2001 Humans|NOTCH2 protein, human|*Receptor, Notch2|Notch Receptors|Serrate-Jagged Proteins|Hematopoietic Stem Cells|Jagged-1 Protein|Membrane Proteins|Receptor, Notch1|Hematopoiesis|Signal Transduction|Cell Lineage|Transcription Factors|Intercellular Signaling Peptides and Proteins|Cell Differentiation|Calcium-Binding Proteins|Bone Marrow Cells|Intracellular Signaling Peptides and Proteins|B Cells | |
11191051 Cancer Metastasis Rev. 2001 Receptor, TIE-2|Angiopoietin-1|Angiopoietin-2|Receptor Protein-Tyrosine Kinases|Neovascularization, Pathologic|Angiopoietins|Growth Factors|Signal Transduction Pathways|Neoplasm Proteins|Proto-Oncogene Proteins|Neovascularization, Physiologic|Membrane Glycoproteins|Vascular Endothelial Growth Factors|Ligands | |
11196150 Cancer Res. 2001 Humans|Mice|Animals|tipifarnib|Mice, Nude|*Quinolones|*Enzyme Inhibitors|p21(ras) farnesyl-protein transferase|Farnesyltranstransferase|Tumor Cell Lines|Apoptosis|Antineoplastic Agents|Protein Prenylation|Cell Proliferation|Xenograft Model Antitumor Assays|imidazole|Imidazoles|Cell Cycle|Dose-Response Relationship, Drug|Angiogenesis Inhibitors|Cell Division | |
11196644 Nature 2001 CD163 antigen|*Antigens, Differentiation, Myelomonocytic|*Antigens, CD|*Receptors, Cell Surface|haptoglobin-hemoglobin complex|Haptoglobin|Hemoglobin|Macrophage|Protein Binding|Endocytosis|Monocytes|Receptors, Scavenger | |
11196645 Nature 2001 Humans|*Fibrinolytic Agents|Platelet Aggregation|Platelets|Antiplatelet Agents|Receptor, ADP|Adenosine Diphosphate|Ticlopidine|Purinergic P2 Receptor Antagonists|Clopidogrel|Cyclase, Adenylyl|Platelet Glycoprotein GPIIb-IIIa Complex|2-propylthio-D-beta,gamma-difluoromethylene ATP|Adenosine Triphosphate|Cyclic AMP|Membrane Proteins|Angina, Unstable | |
11196675 Genes Immun. 2001 Humans|IL10 protein, human|*Interleukin-10|IL19 protein, human|*Interleukins|Base Sequence|cDNA|Amino Acid Sequence|Exons|mRNA|Cloning, Molecular|Introns|Monocytes|Cytokines|IL 13 | |
11201742 Nature 2001 Humans|Axons|Nogo Proteins|Nerve Regeneration|Receptor, Nogo-66|Myelin Proteins|Myelin|Neurites|Growth Cones|Neurons|Myelin-Associated Glycoprotein|Central Nervous System|Receptors, Cell Surface|Ganglia, Spinal|Oligodendrocytes|leucine-rich repeat proteins|GPI-Linked Proteins|*Inhibition, Psychological | |
11201747 Nature 2001 Animals|*RNA Interference|DICER1 protein, human|RNase III|Double-Stranded RNA|DEAD-box RNA Helicases|Argonaute Proteins|RNA, Small Interfering|Messenger RNA|Amino Acid Sequence|Protein Structure, Tertiary|Transfection | |
11204562 Thromb. Haemost. 2001 *Binding Proteins|*Factor XII|*Endothelial Cells|High Molecular Weight Kininogen|Prekallikrein|kininogen 1, human|Kininogens|Receptors, Complement|KRT1 protein, human|*Keratin-1|Membrane Glycoproteins|Bradykinin|Umbilical Veins|Endothelium, Vascular|Mitochondrial Proteins|Cell Surface Proteins|Inflammation|Kallikrein | |
11205333 Philos. Trans. R. Soc. Lond., B, Biol. Sci. 2001 PMC1087693 Humans|Mice|Animals|nurse shark antigen receptor|*Antigen Receptor|Genes, Immunoglobulin|Immunoglobulins|DNA polymerase zeta|DNA-Directed DNA Polymerase|Base Sequence|Somatic Hypermutation, Immunoglobulin|Amino Acid Sequence|DNA Repair|DNA Replication|Mutation|Vertebrates|*Diploidy|DNA|Gene Conversion|Sharks|*Databases, Genetic | |
11207550 Cell. Microbiol. 2001 CEACAM7 protein, human|CEACAM5 protein, human|*Carcinoembryonic Antigen|CD66 antigens|Cell Adhesion Molecules|Antigens, CD|CEACAM6 protein, human|*GPI-Linked Proteins|Neisseria gonorrhoeae|Bacterial Outer Membrane Proteins|Bacterial Adhesion|*Carrier Proteins|Antigens, Bacterial|Neutrophils|Amino Acid Sequence|Escherichia coli | |
11207612 Cell. Microbiol. 2001 Humans|*Shigella flexneri|*Myosin|ezrin|Cytoskeletal Proteins|*Epithelial Cell|Cytoskeleton|Actins|GTPase Activating Protein|Dysentery, Bacillary|Microfilament Proteins|rho GTP-Binding Proteins|Phosphoproteins|Shigella|Signal Transduction|HeLa Cells | |
11208147 Traffic 2001 *Membrane Fusion|*Hemagglutinins|*Influenza, Human|SNAREs|Intracellular Membranes|Orthomyxoviridae|Vesicular Transport Proteins|*Cytoplasm|Lipid Bilayers|Hemagglutinin Glycoproteins, Influenza Virus|Protein Transport|Viral Fusion Proteins|Virion | |
11208594 Am. J. Physiol. Renal Physiol. 2001 NOS3 protein, human|*Nitric Oxide Synthase Type III|Nitric Oxide|Nitric Oxide Synthase|Phosphorylation|Signal Transduction|Endothelium, Vascular|Caveolins|Acylation|Cell Membrane|Endothelial Cell|Serine|*Regulatory B-Cells|Stress, Mechanical | |
11208605 Am. J. Physiol. Renal Physiol. 2001 Animals|Cattle|Humans|*Receptors, Calcium-Sensing|*HEK293 Cells|*Automobiles|*Mitogen-Activated Protein Kinases|MAPK3 protein, human|Extracellular Signal Regulated Kinase 1|Protein Kinase C|Phospholipase C|Phosphorylation|Mitogen-Activated Protein Kinase 1|*Parathyroid Glands|MAP Kinase Signaling System|Enzyme Activation|1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione|Estrenes|*Transfections|Calcium|Phosphatidylinositol Specific Phospholipase C | |
11209945 Neuroreport 2001 Mice|Animals|Paired Box Transcription Factors|Homeodomain Proteins|Protein, Pax-6|Diencephalon|Eye Proteins|Repressor Proteins|Gene Expression Regulation, Developmental|Stem Cells|Pax6 protein, mouse | |
11220739 Ann. Neurol. 2001 Humans|*Electron Transport Complex I|*Mutations|DNA, Mitochondrial|Base Sequence|*Cardiomyopathy|Mitochondria|Polymorphism, Restriction Fragment Length|Amino Acid Sequence|Mutations, Missense|Metabolism, Inborn Errors|Cell Nucleus|DNA Sequencing|NDUFS2 protein, human|NADH Dehydrogenase | |
11221888 Cancer Res. 2001 Humans|HEK293 Cells|*ras Guanine Nucleotide Exchange Factors|Guanine Nucleotide Exchange Factors|1,2-diacylglycerol|Diglycerides|RASGRF1 protein, human|*ras-GRF1|Protein Kinase C|Phorbol Myristate Acetate|ras GTPases|Phosphorylation|DNA-Binding Proteins|Plasma Membrane|RASGRP3 protein, human | |
11222100 Virology 2001 Viral Matrix Proteins|Orthomyxoviridae|Nucleoprotein|*Influenza|Ribonucleoproteins|*Membrane|Protein Binding|Liposomes|Hydrogen-Ion Concentration | |
11222639 J. Neurosci. 2001 PMC6762935 Rats|Animals|Humans|*Neural Cell Adhesion Molecule L1|*Ankyrins|HEK293 Cells|Neural Cell Adhesion Molecules|*Mutations|MASA (Mental Retardation, Aphasia, Shuffling Gait, Adducted Thumbs) Syndrome|Intellectual Disability|Leukocyte L1 Antigen Complex|Neurites|Membrane Glycoproteins|Neurons|Hydrocephalus|Cerebellum|Transfections|Endocytosis|Plasma Membrane|Protein Binding|Spastic Paraplegia, Hereditary | |
11226173 EMBO J. 2001 PMC140193 tRNA|tRNA Methyltransferases|Anticodon|Base Sequence|RNA, Bacterial|Archaea|Nucleic Acid Conformation|Amino Acid Sequence|Bacteria|Reading Frame|Methylation|8-methylguanosine|Guanosine | |
11226175 EMBO J. 2001 PMC140182 Humans|Cricetinae|Animals|*Glycosylphosphatidylinositols|*Mannose|*Endoplasmic Reticulum|Mannosyltransferases|Saccharomyces cerevisiae Proteins|Saccharomyces cerevisiae|Cell Surface Proteins|Amino Acid Sequence|Sequence Alignment|Cloning, Molecular|Sequence Homology, Amino Acid|Transfection|CHO Cells | |
11226238 Proc. Natl. Acad. Sci. U.S.A. 2001 PMC30137 Mice|Animals|*Peroxisome Proliferator-Activated Receptor alpha|*Acids, Fatty|*Hypolipidemic Drugs|FABP1 protein, human|*Liver Fatty Acid-Binding Protein|*Cell Nucleus|Receptors, Cytoplasmic and Nuclear|Fatty Acid-Binding Protein 7|Transcription Factors|Nerve Tissue Proteins|Neoplasm Proteins|Transcription, Genetic|Cytoplasm|Protein Binding|Hepatocytes|Transfections|*Signal Transduction|Promoter Regions, Genetic | |
11226282 Proc. Natl. Acad. Sci. U.S.A. 2001 PMC30181 Receptors, Antigen, B-Cell|Phospholipase C gamma2|Protein-Tyrosine Kinases|Syk Kinase|Phosphorylation|Intracellular Signaling Peptides and Proteins|B Cells|Phosphoproteins|Adaptor Proteins, Signal Transducing|src Homology Domain|Agammaglobulinaemia Tyrosine Kinase|Carrier Proteins|Calcium Signaling|Enzyme Activation|Enzyme Precursors|Tyrosine|Isoenzymes | |
11226752 Int. J. Dev. Neurosci. 2001 Humans|Mice|Animals|*Neurogenesis|*Signal Transduction|Receptors, Notch|Transcription Factors|Drosophila Proteins|Basic Helix-Loop-Helix Transcription Factors|Membrane Proteins|Cell Differentiation|Sequences, Amino Acid|Drosophila|Xenopus laevis|Xenopus Proteins|Gene Expression Regulation, Developmental|Sequence Homology, Amino Acid|Dtx1 protein, mouse|DNA-Binding Proteins|notch protein, Drosophila | |
11230124 EMBO J. 2001 PMC145489 CASP9 protein, human|*Caspase 9|*Apoptosomes|APAF1 protein, human|*Apoptotic Protease-Activating Factor 1|CASP3 protein, human|Caspase 3|Caspases|Apoptosis|X-Linked Inhibitor of Apoptosis Protein|Cytochrome c|System, Cellfree|2'-deoxyadenosine triphosphate|Deoxyadenine Nucleotides | |
11231127 Curr. Biol. 2001 Mice|Animals|*Receptors, Erythropoietin|*Signal Transduction|EPO protein, human|Erythropoietin|Protein Binding|Amino Acid Sequence|Protein Structure, Tertiary|Dimerization|Cell Membrane|Erythroid Progenitor Cells|Mutagenesis|Cell Line|Mutation|Ligands|Point Mutation|*Protein Domains|Transfection | |
11231140 Curr. Biol. 2001 Animals|*Auxilins|Clathrin|HSP40 Heat-Shock Proteins|Adaptor Proteins, Vesicular Transport|HSP70 Heat-Shock Proteins|Molecular Chaperones|Phosphoproteins|Heat-Shock Proteins|Carrier Proteins|Nerve Tissue Proteins|HSC70 Heat-Shock Proteins|Amino Acid Sequence|Adenosine Triphosphatases|Adenosine Triphosphate|clathrin B|*Sesquiterpenes | |
11231159 Curr. Biol. 2001 Animals|Humans|*Nuclear Envelope|*Cell-Free System|*ran GTP-Binding Protein|Guanosine Diphosphate|Chromatin|Nuclear Proteins|Xenopus laevis|Cell Cycle Proteins|Xenopus Proteins|Guanine Nucleotide Exchange Factor|RANGAP1 protein, human|GTPase Activating Protein|Guanosine Triphosphate|Cell Nucleus|DNA-Binding Proteins | |
11231171 Curr. Biol. 2001 Animals|Saccharomyces cerevisiae|Golgi Apparatus|Saccharomyces cerevisiae Proteins|Vesicular Transport Proteins|Endosomes|*Biological Transport|Vacuoles|Membrane Proteins|Carrier Proteins|Receptors, Cell Surface|Cell Compartmentation|Cloning, Molecular | |
11231573 Nat. Cell Biol. 2001 Female|*Phosphorylation|*Proto-Oncogene Proteins c-akt|CDKN1A protein, human|*Cyclin-Dependent Kinase Inhibitor p21|Receptor, ErbB-2|*Cytoplasm|Phosphatidylinositol 3-Kinases|Signal Transduction|Cell Survival|Apoptosis|Cell Division | |
11231579 Nat. Cell Biol. 2001 Animals|*Origin Recognition Complex|*B-DNA|Drosophila|Transcription Factors|Drosophila Proteins|E2F Transcription Factors|Retinoblastoma Protein|Cell Cycle Proteins|Trans-Activators|Drosophila melanogaster|Retinoblastoma-Binding Protein 1|DNA Replication|Carrier Proteins|Replication Origins|S Phase|Cell Cycle|Cell Division|Gene Expression Regulation, Developmental | |
11231581 Nat. Cell Biol. 2001 Humans|Animals|*Influenzavirus B|MAPK-ERK Kinases|*Signal Transduction|*MAP Kinase Signaling System|Mitogen-Activated Protein Kinases|U 0126|Butadienes|Proto-Oncogene Proteins c-raf|*Influenza B virus|Nitriles|Phosphorylation|Cell Proliferation|Cell Division|Cell Cycle|Enzyme Inhibitors | |
11231582 Nat. Cell Biol. 2001 *Arp2-3 Complex|*Filaments, Actin|*Cytoskeleton|WAS protein, human|Wiskott-Aldrich Syndrome Protein|Actin|Actin-Related Protein 3|Actin-Related Protein 2|Microfilament Proteins|Wiskott-Aldrich Syndrome Protein, Neuronal|Protein Binding|Nerve Tissue Proteins|Kinetics | |
11231585 Nat. Cell Biol. 2001 Humans|*S-Phase Kinase-Associated Proteins|Cullin 1|Cullin Proteins|Cyclin-Dependent Kinases|CDKN1B protein, human|Cyclin-Dependent Kinase Inhibitor p27|RBX1 protein, human|CDC2-CDC28 Kinases|*Ubiquitination|Phosphorylation|Ubiquitin-Protein Ligases|Ubiquitins|Cyclin-Dependent Kinase 2|Ubiquitin|Cyclin E|S Phase | |
11231878 BMC Immunol. 2001 PMC31347 Animals|Humans|*Cell Nucleus|Nuclear Proteins|NFATC Transcription Factors|NCYM protein, human|*Neoplasm Proteins|Phosphoproteins|Proto-Oncogene Proteins c-jun|T-Lymphocytes|Binding Sites|Interleukin-2|Promoter Regions, Genetic|Proto-Oncogene Proteins c-fos|Base Sequence|Cytoplasm|DNA | |
11231887 BMC Physiol. 2001 PMC32180 Humans|aquaporin 8|*Colon|*Aquaporins|*Tumors, Colorectal|*Cells, Epithelial|Intestinal Mucosa|RNA, Messenger|Gene Expression | |
11231903 Am. J. Hum. Genet. 2001 PMC1275637 Male|Humans|Adult|DMGDH protein, human|*Dimethylglycine Dehydrogenase|Dimethylglycine Dehydrogenase Deficiency|*Amino Acid Metabolism, Inborn Errors|Sarcosine Dehydrogenase|Oxidoreductases, N-Demethylating|Mitochondrial Proteins|dimethylglycine|Sarcosine|Amino Acid Sequence|Flavin-Adenine Dinucleotide|Glycine|cDNA|DNA|Cloning, Molecular | |
11232563 Science 2001 Humans|Animals|Advanced Sleep-Phase Syndrome, Familial|*Sleep Disorders, Circadian Rhythm|*Phosphorylation|Period Circadian Proteins|*Mutation|Circadian Rhythm|Nuclear Proteins|Biological Clocks|Casein Kinase Iepsilon|Transcription Factors|Missense Mutation|Serine|Drosophila | |
11234019 Nature 2001 Humans|Transcription Factors|DNA-Binding Proteins|*Cyclin-Dependent Kinase Inhibitor p16|Proto-Oncogene Proteins c-ets|*Cellular Senescence|Binding Site|Trans-Activators|Repressor Proteins|Proto-Oncogene Protein c-ets-2|Promoter Regions, Genetic|Proto-Oncogene Proteins|Proto-Oncogene Protein c-ets-1|Divisions, Cell|Transcriptional Activation|Signal Transduction|Genes, Tumor Suppressor|*Cyclin-Dependent Kinase Inhibitor Proteins | |
11237712 Biochem. Biophys. Res. Commun. 2001 Mice|Animals|*Multiple Endocrine Neoplasia Type 2a|GDNF protein, human|*Glial Cell Line-Derived Neurotrophic Factor|*Tyrosine|NIH 3T3 Cells|Signal Transduction|Proto-Oncogene Proteins c-ret|Glial Cell Line-Derived Neurotrophic Factor Receptors|*Mutation|Proto-Oncogene Proteins|Mitogen-Activated Protein Kinases|Phosphatidylinositol 3-Kinases|ras Proteins|Proto-Oncogene Proteins c-akt|Phosphorylation|GRB2 Adaptor Protein|Drosophila Proteins|Phosphoproteins | |
11237722 Biochem. Biophys. Res. Commun. 2001 Humans|Rhizomelic chondrodysplasia punctata, type 2|Chondrodysplasia Punctata, Rhizomelic|Peroxisomal Targeting Signal 2 Receptor|*Genomics|glycerone-phosphate O-acyltransferase|Acyltransferases|Base Sequence|alkylglycerone-phosphate synthase|Alkyl and Aryl Transferases|Exons|Amino Acid Sequence|Plasmalogens|Mutation|*Phosphate Acetyltransferase|Introns|Peroxisomes|Phosphates | |
11237854 Biochem. J. 2001 PMC1221681 Humans|*Ornithine Transcarbamylase|Phosphate, Carbamoyl|Substrate Specificity|Amino Acid Sequence|Crystallography, X-Ray|Aspartate Transcarbamylase|Binding Sites|Active Site|Models, Molecular|Ornithine|Ligands | |
11237865 Biochem. J. 2001 PMC1221692 Humans|*Phosphorylation|*Transcriptional Activation|HEK293 Cells|FOXO1 protein, human|*Forkhead Box Protein O1|AKT1 protein, human|Protein Kinase B alpha|*Cell Nucleus|IGF1 protein, human|Insulin-Like Growth Factor I|Proto-Oncogene Proteins|Forkhead Transcription Factors|Phosphatidylinositol 3-Kinases|Signal Transduction|Serine|Protein Binding|Rhabdomyosarcoma | |
11238108 Blood 2001 Animals|activated protein C receptor|drotrecogin alfa activated|*Protein C|PROCR protein, human|*Endothelial Protein C Receptor|*Blood Coagulation Factors|*Receptors, Cell Surface|THBD protein, human|Thrombomodulin|Thrombin|Fibrinogen|Endothelium, Vascular|Hemostatics|Antibodies, Monoclonal|Thrombosis | |
11238451 J. Cell Biol. 2001 PMC2198800 Humans|*Cyclin B1|*Substrate Specificity|*CDC2 Protein Kinase|Cyclin B2|*Golgi Apparatus|Maturation-Promoting Factor|Mitosis|*Mitogen-Activated Protein Kinase Kinases|Cyclins|Cell Nucleus|Cytoplasm|Cyclin-Dependent Kinases|Phosphorylation|Microtubules|CDK1 protein, human | |
11238463 J. Cell Biol. 2001 PMC2198812 Animals|*Endothelial Cells|Vascular Endothelial Growth Factor A|*Phosphoproteins|*Signal Transduction|Membrane Proteins|Nerve Tissue Proteins|Receptor Protein-Tyrosine Kinases|MAP Kinase Signaling System|Phosphorylation|Mitogen-Activated Protein Kinases|Intracellular Signaling Peptides and Proteins|Epidermal Growth Factor|Plasma Membrane|Adaptor Proteins, Signal Transducing|Protein Binding|Fibroblast Growth Factor|ras Proteins|Amino Acid Sequence | |
11238478 J. Clin. Endocrinol. Metab. 2001 Humans|Male|Adult|Middle Aged|Child|*Hypoaldosteronism|*Cytochrome P-450 CYP11B2|Aldosterone|18-Hydroxycorticosterone|Exon|Homozygote|Mutations|Hyperkalemia|Failure to Thrive | |
11239147 Science 2001 DCC protein, human|*DCC Receptor|*Netrin|NTN1 protein, human|Netrin 1|Growth Cones|Axons|Nerve Growth Factors|Netrin Receptors|Receptors, Cell Surface|Tumor Suppressor Proteins|Cell Adhesion Molecules|Nerve Tissue Proteins|Cell Movement|Signal Transduction|*Cell Membrane | |
11239160 Science 2001 Animals|Rats|NTN1 protein, human|*Netrin-1|*Axon Guidance|*Receptor, Adenosine A2B|DCC Receptor|Axons|Growth Cones|Nerve Growth Factors|Receptors, Cell Surface|Tumor Suppressor Proteins|Signal Transduction|Cell Adhesion Molecules|Spinal Cord|Cell Line|netrin-2|Netrins|Xenopus laevis|Dcc protein, rat | |
11239445 Immunity 2001 Humans|*NK Cell Lectin-Like Receptor Subfamily K|*MHC Class I Molecules|*NK Cells|Receptors, Natural Killer Cell|*Glycoprotein|Cytomegalovirus|Cytotoxicity, Immunologic|Carrier Proteins|Viral Proteins|Intracellular Signaling Peptides and Proteins|Ligands|GPI-Linked Proteins|Down-Regulation|Cell Line|Cytomegalovirus Infections | |
11239454 Mol. Cell 2001 Humans|*Fanconi Anemia Proteins|FANCG Protein|FANCD2 Protein|Fanconi Anemia Complementation Group A Protein|BRCA1 protein, human|*BRCA1 Protein|Fanconi Anemia|Fanconi Anemia Complementation Group C Protein|Fanconi Anemia Complementation Group F Protein|Cell Cycle Proteins|DNA-Binding Proteins|DNA Damage|Cell Nucleus|DNA Repair|Genetic Complementation Test | |
11239457 Mol. Cell 2001 Humans|Animals|*Casein Kinase II|TP53 protein, human|*Tumor Suppressor Protein p53|*DNA Damage|Phosphorylation|DNA-Binding Proteins|Cell Cycle Proteins|Ultraviolet Rays|Serine|Binding Sites|SSRP1 protein, human|High Mobility Group Proteins|Transcriptional Elongation Factors | |
11239468 Mol. Cell 2001 Mice|Animals|*NF-kappa B p52 Subunit|NF-kappa B kinase|NF-kappa B|I-kappa B Kinase|TPX2 protein, human|Cell Cycle Proteins|Phosphorylation|Protein Binding|Cell Line|Transfection|Nuclear Proteins|Mice, Knockout|Microtubule-Associated Proteins | |
11239472 Mol. Cell 2001 *Clathrin|*Phosphoinositide 3-Kinase C2alpha|*Phosphatidylinositol 3-Kinases|Coated Pits, Cell-Membrane|Endocytosis|*Protein Transport|Phosphoinositides|*Cell Movement|trans Golgi Network|synaptojanin|Phosphoric Monoester Hydrolases|Cells, Cultured|Cell Line|Phosphorylation|Nerve Tissue Proteins | |
11241162 J. Mol. Endocrinol. 2001 Female|Infant, Newborn|Humans|*Precursor Cells, B-Lymphoid|nicotinamide phosphoribosyltransferase, human|*Pre-B-Cell Colony-Enhancing Factor|*Cytokines|*Extraembryonic Membranes|Amnion|Interleukin-8|Epithelial Cell|Chorion|IL1B protein, human|Interleukin-1beta|TNF protein, human|TNFalpha|Cells, Cultured|Gene Expression|Lipopolysaccharides|Cell Line|Upregulation | |
11241327 Int. J. Cancer 2001 BCL2 protein, human|Proto-Oncogene Proteins c-bcl-2|Apoptosis|Cell Cycle Proteins|Transcription Factors|DNA-Binding Proteins|TNF protein, human|TNFalpha|Signal Transduction|Protein Phosphatase 1|Sphingosine|Phosphorylation|Transfection | |
11242046 Nature 2001 Excitatory Amino Acid Transporter 3|Glutamate Plasma Membrane Transport Proteins|Glutamate|*Neurons|Excitatory Amino Acid Transporter 1|Biological Transport|Symporters|Membrane Proteins|L-Aspartate|Membrane Transport Proteins|Cell Membrane|Amino Acid Sequence|Cell Line|Sodium | |
11242052 Nature 2001 CASP9 protein, human|*Caspase 9|*Protein A|XIAP protein, human|*X-Linked Inhibitor of Apoptosis Protein|*Apoptosis|Caspases|APAF1 protein, human|Apoptotic Protease-Activating Factor 1|Amino Acid Sequence|Mitochondrial Proteins|Caspase Inhibitors|Carrier Proteins|Caspase 3|Protein Binding|Intracellular Signaling Peptides and Proteins|Sequence Homology, Amino Acid|*Proteolysis | |
11242053 Nature 2001 Mice|Animals|*Methylation|*Histones|*Lysine|*Binding Site|Chromatin|Heterochromatin|Histone-Lysine N-Methyltransferase|Histone Methyltransferases|Chromosomal Proteins, Non-Histone|Repressor Proteins|Phosphorylation|Amino Acid Sequence|Acetylation|*Protein Processing, Post-Translational | |
11242107 Nat. Genet. 2001 Humans|Mice|Animals|*CCAAT-Enhancer-Binding Protein-alpha|*Leukemia, Myeloid, Acute|Mutations|Cell Differentiation|Granulocytes|CEBPA protein, human|CCAAT-Enhancer-Binding Proteins|CEBPA protein, mouse | |
11242108 Nat. Genet. 2001 Male|Mice|Animals|*DNA Breaks, Double-Stranded|*Synapsis|meiotic recombination protein SPO11|Endodeoxyribonucleases|Saccharomyces cerevisiae|Meiosis|Saccharomyces cerevisiae Proteins|Meiotic Prophase I|Spermatocytes|DNA-Binding Proteins|Recombination, Genetic|Histones|Esterases|DNA | |
11242109 Nat. Genet. 2001 Humans|Male|*NF-kappa B|I-kappa B Kinase|*Immunologic Deficiency Syndromes|*Signal Transduction|*Anhydrotic Ectodermal Dysplasia, X-Linked|RELA protein, human|*Transcription Factor RelA|Dysplasia, Ectodermal|TNF protein, human|TNFalpha|Mutations|Osteopetrosis|IKBKG protein, human | |
11242114 Nat. Genet. 2001 Humans|*Serine C-Palmitoyltransferase|*Hereditary Sensory Neuropathy Type I|*Mutations|Exons|Acyltransferases|Genetic Linkage|Ganglia, Dorsal Root|Mutations, Missense|Cell Lines|Nerve Degeneration | |
11243424 J. Cardiovasc. Pharmacol. 2001 Humans|sapropterin|*Vitamin C|*Biopterin|NOS3 protein, human|Endothelial Nitric Oxide Synthase|GTP Cyclohydrolase|Superoxide|Nitric Oxide|Endothelium, Vascular|sepiapterin|Pterins|Peroxynitrite|*Vitamins|Human Umbilical Vein Endothelial Cells|Oxidation-Reduction|Cells, Cultured|Hydrogen Peroxide | |
11243864 Biochem. Biophys. Res. Commun. 2001 CCND1 protein, human|*Cyclin D1|*Retinoblastoma Protein|CDK4 protein, human|*Cdk4 Protein|*Signal Transduction|Cyclin-Dependent Kinases|Proto-Oncogene Proteins|Cyclin-Dependent Kinase 2|*Retinoblastoma|Downregulation|Phosphorylation|*Oligonucleotides|G1 Phase|Tumor Cells, Cultured|Gene Expression Regulation, Neoplastic|Cell Division|Retinal Neoplasms | |
11243884 Biochem. Biophys. Res. Commun. 2001 Animals|Humans|Amino Acid Sequence|Amino Acid Transport Systems|Biological Transport|Amino Acids|Carrier Proteins|Amino Acid Transport Systems, Neutral|Glutamine|Alanine|Asparagine|Cloning, Molecular|mRNA|Xenopus laevis|Sodium|Sequence Homology, Amino Acid|Histidine|*Ion Transport|Tissue Distribution | |
11244049 Annu. Rev. Immunol. 2001 IRF2 protein, human|Interferon Regulatory Factor-2|IRF1 protein, human|Interferon Regulatory Factor-1|viral interferon regulatory factors|Interferon Regulatory Factors|Repressor Proteins|Interferon-Stimulated Gene Factor 3|Phosphoproteins|Interferon-Stimulated Gene Factor 3, gamma Subunit|Gene Expression Regulation|Interferon Regulatory Factor-3|Interferons|Cell Division|Amino Acid Sequence | |
11244088 J. Biol. Chem. 2001 Rats|Animals|NGF protein, human|*Nerve Growth Factor|*Nuclear Factor-Kappab|PKC-3 protein|*Protein Kinase C|Receptor, trkA|Receptor, Nerve Growth Factor|Signal Transduction|Receptors, Neurotrophin|Tifab protein, human|TRAF6|PC12 Cells|Cell Differentiation|Protein Binding | |
11245466 Cancer Res. 2001 Humans|Male|*Prostate|prostein|*Membrane Proteins|Prostate Cancer|Androgens|cDNA|mRNA|Gene Expression Regulation, Neoplastic|Northern Blot|Neoplasm Proteins|Up-Regulation|Amino Acid Sequence|Tumor Cells, Cultured|Cloning, Molecular | |
11245473 Cancer Res. 2001 Humans|Male|*Prostate|*Short Chain Dehydrogenase Family|Androgens|Prostate Cancer|cDNA|Base Sequence|Amino Acid Sequence|Gene Expression Regulation, Neoplastic|Blotting, Northern|RNA, Messenger|In Situ Hybridization|Promoter Regions, Genetic|Chromosome Mapping|*Steroids | |
11247302 Traffic 2001 LDLR protein, human|*Low Density Lipoprotein Receptor|Clathrin|Adaptor Protein Complex 2|Adaptor Proteins, Signal Transducing|alpha Adaptin|Endocytosis|Adaptor Proteins, Vesicular Transport|Protein Binding|Amino Acid Sequence|Membrane Proteins|Tumor Suppressor Proteins|Protein Transport|Peptides|Cell Membrane | |
11247303 Traffic 2001 *Class I Major Histocompatibility Molecules|Antigen Processing|Histocompatibility Antigens Class II|Endosomes|T-Lymphocytes, Cytotoxic|Antigens|Lysosomes|Biological Transport|Endoplasmic Reticulum|Peptides|Dendritic Cells|Lymphocyte Activation|Membrane Transport Proteins|Plasma Membrane|ATP-Binding Cassette Transporters | |
11247665 Genomics 2001 Humans|Rats|Animals|*Solute Carrier 26 Family|Amino Acid Sequence|Anion Transport Proteins|Base Sequence|Deafness, Autosomal Recessive 6|Hearing Loss, Sensorineural|Exons|Cloning, Molecular|Chromosome Mapping|Biological Transport|Carrier Proteins|Sequence Homology, Amino Acid|Proteins|Pendred syndrome|Blotting, Northern|DNA, Complementary|Ion Transport|SLC26A6 protein, human | |
11247674 Genomics 2001 Humans|Animals|*Glucose Transport Facilitators|*Diabetes Mellitus, Type 2|*Cloning, Molecular|*Membrane Transport Proteins|Monosaccharide Transport Proteins|*Chromosome Structures|*Chromosome 1|*Diabetes Mellitus, Type 1|Amino Acid Sequence|DNA, Complementary|Sequence Homology, Amino Acid|RNA, Messenger | |
11248093 Proc. Natl. Acad. Sci. U.S.A. 2001 PMC30668 Mice|Animals|*DCC Receptor|*Colorectal Cancer|Genes, Tumor Suppressor|Tumor Suppressor Proteins|Genes, DCC|CASP9 protein, human|Caspase 9|Netrin-1|Receptors, Cell Surface|Nerve Growth Factors|Apoptosis|*Colonic Neoplasms|*Cell Death|CASP3 protein, human|Caspase 3|*Proteolysis|Dcc protein, mouse | |
11248116 Proc. Natl. Acad. Sci. U.S.A. 2001 PMC30691 Rats|Animals|*Receptors, Neurotrophin|tropomyosin-related kinase-B, human|Receptor, trkB|trkA Receptor|NGF protein, human|Nerve Growth Factor|Signal Transduction|PC12 Cells|BDNF protein, human|Brain-Derived Neurotrophic Factor|Phosphorylation|G-Protein-Coupled Receptors|Neurons|2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine|Phenethylamines|Adenosine|Receptors, Adenosine|Cell Survival | |
11248239 FEBS Lett. 2001 Humans|*ATP-Binding Cassette Transporters|ABCD1 protein, human|Adrenoleukodystrophy Protein|Adrenoleukodystrophy|ATP Binding Cassette Transporter, Subfamily D|Peroxisomes|Membrane Protein|*Amino Acid Sequence|Adenosine Triphosphate|Dimerization|*Chloride Channels|Mutations|Hydrolysis | |
11248244 FEBS Lett. 2001 Humans|*Nicotinamide Mononucleotide Adenylyltransferase|*NAD|*Nicotinamide Mononucleotide|glutamine-synthetase adenylyltransferase|Amino Acid Sequence|*Cell Nucleus|PARP1 protein, human|Poly (ADP-Ribose) Polymerase-1|ADP Ribose, Poly|Saccharomyces cerevisiae|DNA Sequence|*Biochemical Phenomena | |
11250149 Curr. Biol. 2001 Animals|INSR protein, human|*Receptor, Insulin|*Drosophila|*Somatomedins|Drosophila Proteins|PI-3 Kinase|Signal Transduction|*Antigens, CD|Insulin Receptor Substrate Proteins|Receptor Protein-Tyrosine Kinases|Genes, Insect|Cell Size|Carrier Proteins|Insulin|Cell Division | |
11250653 J. Endocrinol. 2001 Humans|IGFBP3 protein, human|*Insulin-Like Growth Factor Binding Protein 3|IGF2 protein, human|IGF-2|IGF1 protein, human|IGF-1|Protein Binding|Recombinant Proteins|IGFBP|Binding Site|Amino Acid Sequence|Phosphorylation|IGFBP1 protein, human|Insulin-Like Growth Factor Binding Protein 1 | |
11250728 Breast Cancer Res. 2001 PMC138657 *Receptors, Estrogen|*Transcriptional Activation|*DNA|Amino Acid Sequence|Binding Sites|Transcription Factors|Transcription, Genetic|Ligands|Response Elements|Estradiol|*Protein Domains|Estrogens|Structure-Activity Relationship | |
11250901 EMBO J. 2001 PMC145524 Animals|*RNA Polymerase I|*Acetylation|TTF1 protein, human|*Transcription Factors|SET protein, human|DNA-Binding Proteins|Pol1 Transcription Initiation Complex Proteins|*Histone Chaperones|TATA-Box Binding Protein|Transcription, Genetic|*Cell Nucleolus|rDNA|p300-CBP-associated factor|p300-CBP Transcription Factors|Promoter Regions, Genetic|RNA, Ribosomal|Acetyltransferase, Histone|Genes, Reporter | |
11250908 EMBO J. 2001 PMC145529 *Dimerization|Saccharomyces cerevisiae Proteins|Saccharomyces cerevisiae|Protein Kinase|Histidyl-tRNA Synthetase|Phosphorylation|tRNA|DNA-Binding Proteins|Protein-Serine-Threonine Kinases|Eukaryotic Initiation Factor-2|Binding Sites|Sequence Homology, Amino Acid|Mutation|Amino Acids|GCN2 protein, S cerevisiae | |
11250913 EMBO J. 2001 PMC145539 Humans|Pol beta protein, human|*DNA Polymerase beta|*DNA Replication|Base Excision Repair|*DNA|DNA Polymerases|Flap Endonucleases|Nucleotides | |
11252672 Acta Virol. 2001 *Influenza A virus|Genome, Viral|Complementary RNA|RNA, Viral|RNA Polymerase|RNA-Dependent RNA Polymerase|Nucleoprotein|mRNA|Transcription, Genetic|RNA primers|Virus Replication|Promoter Regions, Genetic | |
11252894 Nat. Rev. Mol. Cell Biol. 2001 COP-Coated Vesicles|Coat Protein Complex I|Golgi Apparatus|Coated Vesicles|Biological Transport|Clathrin|Protein Transport|Endoplasmic Reticulum|Models, Biological | |
11252952 Nat. Rev. Mol. Cell Biol. 2001 Endocytosis|Exocytosis|rab GTP-Binding Proteins|TYRP1 protein, human|*Membrane Glycoproteins|Protein Transport|Organelles | |
11254356 Dev. Biol. 2001 Animals|Mice|Homeodomain Proteins|Transcription Factors|Enhancer Elements, Genetic|Hindbrain|Gene Expression Regulation, Developmental|Xenopus Proteins|Mesoderm|Base Sequence|Sequence Homology, Nucleic Acid|Animals, Genetically Modified|Reporter Gene | |
11256625 EMBO Rep. 2001 PMC1083685 *Nuclear Pore Complex Proteins|Nucleocytoplasmic Transport Proteins|Nuclear Pore Complex|Active Transport, Cell Nucleus|Nuclear Proteins|RNA-Binding Proteins|Cell Nucleus|Amino Acid Sequence|Protein Binding|Saccharomyces cerevisiae|Binding Sites|RNA, Messenger|ATP-Binding Cassette Transporters|Dimerization | |
11256994 J. Cell. Sci. 2001 Humans|*Receptor, Oxidized LDL|Endothelial Cells|Scavenger Receptors, Class E|Receptors, LDL|Amino Acid Sequence|*Lectins|*Cell Membrane|Lipoproteins, LDL|Folding, Protein|Ligands|Sequence Homology, Amino Acid|Membrane Proteins|Cloning, Molecular|Glycosylation|*Carbohydrate | |
11257230 Cell 2001 *Caspase 7|CASP3 protein, human|Caspase 3|Caspases|Caspase Inhibitors|X-Linked Inhibitor of Apoptosis Protein|Protein Structure, Tertiary|Caspase 9|Inhibitor of Apoptosis Proteins|Mitochondrial Proteins|Amino Acid Sequence|Carrier Proteins|Crystallography, X-Ray|Apoptosis|Intracellular Signaling Peptides and Proteins|Models, Molecular|Peptides|Cell Death | |
11257231 Cell 2001 Humans|*Caspase Inhibitors|Caspases|Protein Binding|X-Linked Inhibitor of Apoptosis Protein|Caspase-7|Protein Structure, Tertiary|Amino Acid Sequence|Carrier Proteins|Mitochondrial Proteins|Caspase 9|Intracellular Signaling Peptides and Proteins|Inhibitor of Apoptosis Proteins|Caspase 3|Apoptosis|Sequence Homology, Amino Acid|*Protein Domains|XIAP protein, human | |
11257510 Biochim. Biophys. Acta 2001 *Glucagon-Like Peptide-1 Receptor|Pertussis Toxin|Guanosine 5'-O-(3-Thiotriphosphate)|GTP-Binding Protein alpha Subunits, Gi-Go|GTP-Binding Protein alpha Subunits, Gs|Signal Transduction|G Proteins|Virulence Factors, Bordetella|Adenylate Cyclase Toxin|Cell Membranes|*Cytoplasm|Cholera Toxin|GTP Phosphohydrolases|Amino Acid Sequence | |
11259411 J. Biol. Chem. 2001 Humans|Animals|*Active Transport, Cell Nucleus|*Cell Nucleus|Nucleocytoplasmic Transport Proteins|RNA-Binding Proteins|Nuclear Proteins|Messenger RNA|*Dimerization|*RNA Transport|Saccharomyces cerevisiae Proteins|Saccharomyces cerevisiae|Amino Acid Sequence|Protein Binding|Binding Sites|Caenorhabditis elegans|Sequence Homology, Amino Acid|ATP-Binding Cassette Transporters|RNA | |
11259413 J. Biol. Chem. 2001 Humans|BGN protein, human|*Biglycan|*Decorin|Glycosaminoglycans|Extracellular Matrix Proteins|Binding Site|Protein Binding|Collagen Type VI|Binding, Competitive|Kinetics|Protein Structure, Tertiary|Surface Plasmon Resonance|Recombinant Proteins|Chondroitinase ABC|Pepsin | |
11259415 J. Biol. Chem. 2001 Humans|Male|Chlorocebus aethiops|Mice|Animals|*Interferon|*Downregulation|NEDD8 protein, human|*NEDD8 Protein|Ubiquitins|Transcription Factors|Proteasome Endopeptidase Complex|Two-Hybrid System Techniques|Cullins|Protein Binding|*Antiviral Agents|Transfection|Cell Nucleus|Cysteine Endopeptidases|Blotting, Western|cDNA|COS Cells|Nub1 protein, mouse | |
11259583 Mol. Cell. Biol. 2001 PMC86867 *Mitochondrial Membranes|TOM translocase|*Carrier Proteins|Saccharomyces cerevisiae|Saccharomyces cerevisiae Proteins|Mitochondrial Membrane Transport Proteins|Membrane Transport Proteins|Mitochondria|Membrane Proteins|TYRP1 protein, human|*Membrane Glycoproteins|Biological Transport|Receptors, Cytoplasmic and Nuclear|Protein Transport|Protein Precursors|Protein Binding|TOM22 protein, S cerevisiae|Tom40 protein, S cerevisiae | |
11259602 Mol. Cell. Biol. 2001 PMC86886 Humans|Animals|*Introns|*RNA|Nucleoporins|Nucleocytoplasmic Transport Proteins|Export, Nuclear|Nuclear Proteins|RNA-Binding Proteins|Cytoplasm|Cell Nucleus|Gene Products, rev|RNA, Messenger|Amino Acid Sequence|Protein Binding|ATP-Binding Cassette Transporters|NXT1 protein, human | |
11259606 Mol. Cell. Biol. 2001 PMC86890 *Receptors, Aryl Hydrocarbon|*HSP90 Heat-Shock Proteins|Protein Binding|Aryl Hydrocarbon Receptor Nuclear Translocator|Ligands|*Cytoplasm|Helix-Loop-Helix Domain|pendulin|Nuclear Proteins|Dioxins|Gene Expression Regulation|Signal Transduction | |
11262391 J. Biol. Chem. 2001 *Lymphoma, B-Cell, Marginal Zone|*NF-kappa B|*Translocation, Genetic|BCL10 protein, human|*B-Cell CLL-Lymphoma 10 Protein|*Mucosa-Associated Lymphoid Tissue Lymphoma Translocation 1 Protein|*Signal Transduction|Caspases|Familial primary gastric lymphoma|*Stomach Neoplasms|Adaptor Proteins, Signal Transducing|Oncogene Proteins, Fusion|Apoptosis | |
11262396 J. Biol. Chem. 2001 Humans|*Lymphocyte Activation|*Interleukin-2|*Serum Response Element|*Transcriptional Activation|*Genes, fos|VAV1 protein, human|Proto-Oncogene Proteins c-vav|T Cell Receptor|*Proto-Oncogene Proteins c-fos|SLP-76 signal Transducing adaptor proteins|Adaptor Proteins, Signal Transducing|NFATC Transcription Factors|DNA-Binding Proteins|Nuclear Proteins|Cell Cycle Proteins|Signal Transduction|src Homology Domains|Proto-Oncogene Proteins | |
11264294 J. Biol. Chem. 2001 Pregnancy|Animals|Female|IGFBP5 protein, human|*Insulin-Like Growth Factor Binding Protein 5|*Pregnancy-Associated Plasma Protein B|*Proteolysis|LY 165163|Insulin-Like Growth Factor Binding Protein 4|Pregnancy Associated Plasma Protein A|*Endopeptidases|IGF1 protein, human|IGF-1|Blood Proteins|Protein Binding|Recombinant Proteins|Amino Acid Sequence|Blotting, Western|Binding Sites|Protein Structure, Tertiary|Electrophoresis, Polyacrylamide Gel | |
11264352 J. Virol. 2001 PMC114854 Humans|*Reverse Transcription|*HIV-1|HIV Reverse Transcriptase|strong-stop DNA|DNA, Viral|*Cytoplasm|Capsid|Cell Nucleus|Transcription, Genetic | |
11264579 Acta Crystallogr. D Biol. Crystallogr. 2001 Humans|branched-chain-amino-acid transaminase|Escherichia coli|Protein Conformation|Crystallography, X-Ray|D-Alanine Transaminase|Binding Sites|Amino Acid Sequence|Models, Molecular|Substrate Specificity|Pyridoxal Phosphate|Hydrogen Bond|*Mitochondria|Alanine Transaminase|Active Site|Macromolecular Substances|Lysine | |
11265639 Eur. J. Immunol. 2001 Humans|*NK Cells|Cytotoxicity, Immunologic|NCR1 protein, human|Natural Cytotoxicity Triggering Receptor 1|Lymphocyte Activation|Receptors, Immunologic|CD56 Antigen|Surface Antigen|T Cells|Receptors, IgG|Antibodies, Monoclonal|Antigens, CD | |
11265756 EMBO Rep. 2001 PMC1084265 Animals|*Selenocysteine|*Eukaryotes|Selenoprotein|UGA Codons|*Eukaryotic Cells|Protein Biosynthesis|3' Untranslated Region|mRNA|Elongation Factor|RNA, Transfer, Amino Acyl|RNA-Binding Proteins|Prokaryotic Cells|Base Sequence|Nucleic Acid Conformation|Protein Structure, Secondary|Selenium | |
11266540 Nucleic Acids Res. 2001 PMC31284 Animals|*TCF Transcription Factors|*Co-Repressors|CTNNB1 protein, human|beta Catenin|Transcription Factors|Repressor Proteins|Trans-Activators|Drosophila|Basic Helix-Loop-Helix Transcription Factors|Drosophila Proteins|Armadillo Domain Proteins|Lymphoid Enhancer-Binding Factor 1|Activation, Transcriptional|Protein Binding|Signal Transduction|*Burkitt Lymphoma|groucho protein, Drosophila | |
11267664 Biochim. Biophys. Acta 2001 Humans|Rats|Animals|*5-Aminolevulinate Synthetase|*Alternative Splicing|*Rodent|HeLa Cells|TATA Box|Exon|Promoter Regions, Genetic|Base Sequence|Transcription, Genetic|mRNA|Binding Sites|RNA Splicing|Transfections|Gene Expression Regulation, Enzymologic|Mutagenesis, Site-Directed | |
11269501 EMBO Rep. 2001 PMC1083746 Animals|*Drosophila|*NF-kappa B|Drosophila Proteins|Drosophila melanogaster|RELA protein, human|*Transcription Factor RelA|I-kappa B Proteins|Signal Transduction|Caspases|Promoter Regions, Genetic|Phosphorylation|Cell Nucleus|Cecropins | |
11274057 Genes Dev. 2001 PMC312660 Humans|*Proliferating Cell Nuclear Antigen|G-T mismatch-binding protein|*DNA-Binding Proteins|MSH3 protein, human|*MutS Homolog 3 Protein|DNA Repair|Base Pair Mismatch|Protein Binding|Mismatch Repair|Amino Acid Sequence|Adenosine Triphosphatases|DNA|Cyclins|Cyclin-Dependent Kinase Inhibitor p21 | |
11274138 J. Biol. Chem. 2001 Humans|*Telomerase|*HSP90 Heat-Shock Proteins|*HSP70 Heat-Shock Proteins|Molecular Chaperones|Heat-Shock Proteins|Protein Binding|DNA-Binding Proteins|RNA | |
11274165 J. Biol. Chem. 2001 Animals|Humans|lipopolysaccharide B|*Lipopolysaccharides|*Toll-Like Receptor 4|HEK293 Cells|Lymphocyte Antigen 96|Toll-Like Receptors|Lipopolysaccharide Receptors|*Cell Membrane|Membrane Glycoproteins|Antigens, Surface|Signal Transduction|Protein Binding|Transfection|Drosophila Proteins|Blotting, Western|TLR4 protein, human | |
11274177 J. Biol. Chem. 2001 Humans|Cattle|Animals|Mice|*Heparin|*Heparitin Sulfate|Iduronic Acid|Carbohydrate Epimerases|Glucuronic Acid|cDNA|Amino Acid Sequence|Recombinant Proteins|Sequence Homology, Amino Acid|Lung|Amino Acids | |
11274386 Proc. Natl. Acad. Sci. U.S.A. 2001 PMC31113 Mice|Animals|*Phosphorylation|*Proto-Oncogene Proteins c-akt|NR4A1 protein, human|*Nuclear Receptor Subfamily 4, Group A, Member 1|Receptors, Steroid|T-Cell Antigen Receptor|Transcriptional Activation|Gene Expression Regulation|Apoptosis | |
11274389 Proc. Natl. Acad. Sci. U.S.A. 2001 PMC31117 Animals|Female|Humans|*X-Rays|*Retinol-Binding Proteins|Retinol-Binding Proteins, Cellular|Retinol|Retinoids|Amino Acid Sequence|mRNA|*Radiography|Molecular Model|iota crystallin|Crystallins | |
11274402 Proc. Natl. Acad. Sci. U.S.A. 2001 PMC31139 *Transforming Growth Factor beta|SMAD3 protein, human|*Smad3 Protein|MEN1 protein, human|*Proto-Oncogene Proteins|Multiple Endocrine Neoplasia Type I|*Signal Transduction|Trans-Activators|Neoplasm Proteins|Gene Expression Regulation|Transforming Growth Factors | |
11276087 Proteins 2001 Humans|lactate dehydrogenase 1|*Isoenzymes|*Lactate Dehydrogenase|Protein Conformation|Kinetics|Pyruvate|Active Site|NAD|Binding Sites|Crystallography, X-Ray|Models, Molecular|Lactate | |
11276226 Nat. Neurosci. 2001 Animals|Chlorocebus aethiops|LIMK1 protein, human|*Lim Kinases|*Phosphorylation|*Semaphorin-3A|*Growth Cones|*Microfilament Proteins|Actin|Actin Depolymerizing Factors|Actin Cytoskeleton|Ganglia, Dorsal Root|Protein Kinases|Protein-Serine-Threonine Kinases|Cytoskeleton|Signal Transduction|COS Cells|Neurons | |
11277919 Eur. J. Biochem. 2001 Humans|*Nucleoside Diphosphate Kinase C|Kinases, Nucleoside-Diphosphate|Transcription Factors|*Catalysis|Amino Acid Sequence|Monomeric GTP-Binding Proteins|Sequence Homology, Amino Acid|*Molecular Dynamics Simulation|*Models, Chemical|Kinetics|Cell Differentiation | |
11278251 J. Biol. Chem. 2001 TGFBR1 protein, human|*Receptor, Transforming Growth Factor-beta Type I|SMAD7 protein, human|*Smad7 Protein|Receptors, Transforming Growth Factor beta|Transforming Growth Factor beta|E3 Ubiquitin Ligase|Signal Transduction|Phosphorylation|Protein-Serine-Threonine Kinases|Trans-Activators|Smad2 Protein|DNA-Binding Proteins|Activin Receptors, Type I|Protein Binding|Bone Morphogenetic Protein|Ubiquitin|Cytoplasm | |
11278253 J. Biol. Chem. 2001 Humans|TP53 protein, human|*Tumor Suppressor Protein p53|*Transcriptional Activation|*Caspase 1|HeLa Cells|Promoter Regions, Genetic|Genes, p53|Apoptosis|Transfection|Binding Site|Transcription, Genetic|mRNA|Base Sequence|Doxorubicin|Protein Binding|Mutation | |
11278283 J. Biol. Chem. 2001 Humans|Animals|Mice|HeLa Cells|*Caspases|*Apoptosis|CASP3 protein, human|Caspase 3|*Cell Death|SLK protein, human|Serine Threonine Kinase|fas Receptor|Staurosporine|*Protein Processing, Post-Translational|Cytoplasm|Cell Nucleus|Phosphorylation|cDNA|*Proteolysis | |
11278287 J. Biol. Chem. 2001 Rats|Animals|Humans|HEK293 Cells|NGFR protein, human|Receptors, Nerve Growth Factor|*Receptor-Mediated Signal Transduction|Receptor, Nerve Growth Factor|Nerve Tissue Proteins|Apoptosis|*Protein Binding|Apoptosis Regulatory Proteins|PC12 Cells|Nerve Growth Factors|Nerve Cells|Oligodendrocytes|Cell Cycle|Two-Hybrid System Techniques | |
11278319 J. Biol. Chem. 2001 Swine|Animals|FLT1 protein, human|*Vascular Endothelial Growth Factor Receptor-1|neuropilin-2, human|*Neuropilin-2|VEGFA protein, human|*Vascular Endothelial Growth Factor A|Endothelial Cells|Neuropilin-1|Receptors, Vascular Endothelial Growth Factor|Vascular Endothelial Growth Factors|Receptor Protein-Tyrosine Kinases|Receptors, Growth Factor|Cell Signaling|Phosphorylation|Protein Binding|Protein Isoforms|Endothelium, Vascular|Binding Sites | |
11278339 J. Biol. Chem. 2001 Rats|Animals|*Insulin Receptor Substrate Proteins|*Phosphorylation|Phosphatidylinositol 3-Kinases|B-insulin|*Insulin|INSR protein, human|Insulin Receptor|Proto-Oncogene Proteins c-akt|Phosphoproteins|Signal Transduction|Wortmannin|Serine|*Biotin|Phosphoserine|PRKCA protein, human|Protein Kinase C-alpha|Tyrosine|Antigens, CD | |
11278435 J. Biol. Chem. 2001 *Proto-Oncogene Proteins c-akt|*MAP Kinase Signaling System|MAPK3 protein, human|*Mitogen-Activated Protein Kinase 3|*Apoptosis|2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one|Chromones|Morpholines|Canertinib|Phosphorylation|Phosphoinositide-3 Kinase Inhibitors|gemcitabine|Deoxycytidine|2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one|Flavonoids|Phosphatidylinositol 3-Kinases|Receptor, ErbB-2|Mitogen-Activated Protein Kinases | |
11278437 J. Biol. Chem. 2001 Rats|Animals|*Phosphorylation|*Thrombin|*Muscle, Smooth, Vascular|*Heat Shock Proteins|JAK2 protein, human|Janus Kinase 2|alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide|Tyrphostins|*Kinases, Janus|STAT1 protein, human|STAT1 Transcription Factor|STAT3 Transcription Factor|Signal Transduction|Trans-Activators|Mitogen-Activated Protein Kinase 1|Mitogen-Activated Protein Kinase 3|Cell Nucleus|Tyrosine | |
11278445 J. Biol. Chem. 2001 Rats|Animals|*PC12 Cells|NGF protein, human|*Nerve Growth Factor|*Epidermal Growth Factor|*MAP Kinase Signaling System|MAPK1 protein, human|Mitogen-Activated Protein Kinase 1|Signal Transduction|MAPK3 protein, human|Mitogen-Activated Protein Kinase 3|Extracellular Signal-Regulated MAP Kinases|Phosphorylation|Neurites|Cell Differentiation|Cellular Proliferation|Proto-Oncogene Proteins B-raf|Small G-Proteins | |
11278468 J. Biol. Chem. 2001 Humans|Swine|Mice|Animals|KDR protein, human|*Vascular Endothelial Growth Factor Receptor-2|*Phosphatidylinositol 3-Kinase|*Vascular Endothelial Growth Factor A|*Tyrosine|Phosphatidylinositol 3-Kinases|Receptor Protein-Tyrosine Kinases|Signal Transduction|Receptors, Growth Factor|Receptors, Vascular Endothelial Growth Factor|*Cell Proliferation|Phosphorylation|Vascular Endothelial Growth Factor Receptor-1|Cell Migration|Mitogen-Activated Protein Kinases|Endothelium, Vascular|Cell Division|Wortmannin | |
11278486 J. Biol. Chem. 2001 *Phosphorylation|PAK1 protein, human|p21-Activated Kinases|Cell Cycle Proteins|cdc42 GTP-Binding Protein|Protein Binding|Enzyme Activation|Protein Structure, Tertiary|rac GTP-Binding Proteins|Amino Acid Sequence|Catalytic Domain|Serine | |
11278508 J. Biol. Chem. 2001 Rats|Animals|AroP protein, E coli|*Amino Acid Transporter|*Cloning, Molecular|Biological Transport|Carrier Proteins|*Escherichia coli Proteins|Amino Acids|*Sodium|Amino Acid Sequence|Xenopus laevis|cDNA|*Ions|mRNA|Oocytes|Substrate Specificity|Tissue Distribution|Aromatic Amino Acids | |
11278511 J. Biol. Chem. 2001 Humans|*Thymidylate Synthase|Deoxyuracil Nucleotides|Protein Conformation|Binding Sites|Kinetics|Protein Binding|Crystallography, X-Ray|Models, Molecular|Hydrogen Bonding|Amino Acid Sequence|Substrate Specificity|Catalysis|Crystallization|Mutagenesis, Site-Directed|Dimerization|Enzyme Inhibitors|Folate | |
11278729 J. Biol. Chem. 2001 Humans|Mice|Animals|STAT3 protein, human|*STAT3 Transcription Factor|HGF protein, human|*Hepatocyte Growth Factor|CSK protein, human|*CSK Tyrosine-Protein Kinase|src Tyrosine Kinases|Phosphorylation|Protein-Tyrosine Kinases|STAT1 protein, human|STAT1 Transcription Factor|Trans-Activators|Signal Transduction|Protein Binding|*Breast Carcinoma | |
11278778 J. Biol. Chem. 2001 *Saccharomyces cerevisiae|*Dolichol|*Glycosylation|mannosyl(5)-N-acetyl(2)-glucose|*Endoplasmic Reticulum|*Oligosaccharides|*Cytosol|Saccharomyces cerevisiae Proteins|*Yeast, Dried|Mannosyltransferases|Polyisoprenyl Phosphate Oligosaccharides|Amino Acid Sequence|Membrane Protein|Yeast, Fission|Mannan|*MEN 2|Polysaccharides | |
11278797 J. Biol. Chem. 2001 Male|*Caspases|Tyrosine Kinase|Phosphorylation|src Homology Domains|platelet protein P47|Phosphoproteins|src-Family Kinases|Blood Proteins|Enzyme Activation|Protein Binding|Apoptosis|*Proteolysis|Cell Line | |
11278832 J. Biol. Chem. 2001 Animals|Humans|*Inosine Triphosphate|inosine triphosphatase|*Pyrophosphatases|ITPA protein, human|Amino Acid Sequence|Cloning, Molecular|cDNA|xanthosine 5'-triphosphate|Ribonucleotides|Hydrolysis|Sequence Homology, Amino Acid | |
11278841 J. Biol. Chem. 2001 *Amyloid Precursor Protein Secretases|*Phosphorylation|Amyloid beta-Peptides|Aspartic Acid Endopeptidases|APP protein, human|Amyloid beta-Protein Precursor|*Protein Transport|Endosomes|Golgi Apparatus|Cell Membrane|Alzheimer Disease|Biological Transport|*Cell Movement|Amino Acid Sequence|Protein Structure, Tertiary|Glycosylation|Cell Line | |
11278854 J. Biol. Chem. 2001 Mice|Animals|*Genes, Homeobox|Homeodomain Proteins|Transcription Factors|Enhancer Elements, Genetic|Hindbrain|Binding Site|Pre-B-Cell Leukemia Transcription Factor 1|Mice, Transgenic|Gene Expression Regulation, Developmental|Base Sequence|Retinoic Acid|Reporter Gene | |
11278856 J. Biol. Chem. 2001 Humans|*Pyrimidine Dimers|*Replication Protein A|DDB2 protein, human|*DNA-Binding Proteins|DNA Repair|DNA Damage|Xeroderma Pigmentosum Group A Protein|Xeroderma Pigmentosum|DNA|Ultraviolet Rays|Protein Binding|Cell Line|Cisplatin|*Chromosome Structures|Recombinant Proteins|Kinetics|Dimerization|XPA protein, human | |
11278936 J. Biol. Chem. 2001 Humans|Mice|Animals|CD39 antigen|*Apyrase|*Cloning, Molecular|*Antigens, CD|Amino Acid Sequence|Sequence Alignment|Base Sequence|DNA, Complementary|Sequence Homology, Amino Acid|Pyrophosphatases|Chromosome Mapping|Introns|*Mammals|Blotting, Northern|Exons | |
11278984 J. Biol. Chem. 2001 Rats|Mice|Animals|*Integral Membrane Protein|protein C propeptide|*Protein C|Pulmonary Surfactants|Pulmonary Surfactant-Associated Protein A|Proteolipids|Lung|Transfections|Cell Line|*Secretion|Protein Processing, Post-Translational|Cells, Cultured|Surface-Active Agents|Peptides|Protein Precursors | |
11279012 J. Biol. Chem. 2001 Humans|Animals|HeLa Cells|sty protein, Drosophila|Membrane Proteins|*Cell Migration|Drosophila Proteins|Intracellular Signaling Peptides and Proteins|Epidermal Growth Factor|Proto-Oncogene Proteins c-cbl|Nerve Tissue Proteins|ErbB Receptors|Phosphorylation|Transfections|Isoforms|Fibroblast Growth Factor|Cell Proliferation | |
11279095 J. Biol. Chem. 2001 Humans|Animals|Chlorocebus aethiops|CMP-N-acetylneuraminate-poly-alpha-2,8-sialosyl sialyltransferase|Sialyltransferases|Neural Cell Adhesion Molecule|Sialic Acids|Amino Acid Sequence|Mutagenesis, Site-Directed|Transfection|COS Cells|Cysteine|*Protein Domains|Disulfides | |
11279128 J. Biol. Chem. 2001 PRKDC protein, human|*DNA-Activated Protein Kinase|*Ku Autoantigen|*Phosphorylation|*Proteins, Homeo Domain|Nuclear Proteins|Antigens, Nuclear|DNA Helicases|Transcription Factors|Saccharomyces cerevisiae Proteins|Saccharomyces cerevisiae|Protein Binding|Binding Sites|DNA|Amino Acid Sequence|Genes, Homeobox|Dimerization|cDNA Library | |
11279134 J. Biol. Chem. 2001 Mice|Animals|*3T3-L1 Cells|*C EBPbeta|*Adipogenesis|*PPAR gamma|C EBPalpha|Adipocytes|Cell Differentiation|CCAAT-Enhancer-Binding Proteins|Transcription, Genetic|Troglitazone|Promoter Regions, Genetic|FABP2 protein, human|Fatty Acid-Binding Proteins | |
11279143 J. Biol. Chem. 2001 Humans|Xeroderma Pigmentosum, Complementation Group C|*Xeroderma Pigmentosum|caltractin|*Nucleotide Excision Repair|*Calcium-Binding Proteins|*Chromosomal Proteins, Non-Histone|*Centrosome|DNA Damage|DNA-Binding Proteins|Cell Cycle Proteins|Protein Binding|TYRP1 protein, human|*Membrane Glycoproteins|Cell Nucleus | |
11279148 J. Biol. Chem. 2001 BTK protein, human|*Bruton Tyrosine Kinase|*Phosphatidylinositol|*Pleckstrin Homology Domains|proto-oncogene protein c-fes-fps|Protein-Tyrosine Kinases|Phosphorylation|*Inositol Phosphates|Phosphatidylinositol Phosphates|PtdIns 3-Kinase|Enzyme Activation|Proto-Oncogene Proteins|Proto-Oncogene Proteins c-akt|Protein Binding|Phosphoproteins|Binding Sites|Signal Transduction|Transfection | |
11279150 J. Biol. Chem. 2001 Humans|Animals|Mice|Drosophila melanogaster|heparin-heparan sulfate-glucuronic acid C5-epimerase|*Carbohydrate Epimerases|Iduronic Acid|Amino Acid Sequence|cDNA|Recombinant Proteins|Cloning, Molecular|Sequence Homology, Amino Acid|Cell Line|Glucuronic Acid|Heparin|Caenorhabditis elegans|Heparitin Sulfate | |
11279162 J. Biol. Chem. 2001 Animals|Humans|*1-Phosphatidylinositol 4-Kinase|Amino Acid Sequence|Saccharomyces cerevisiae Proteins|Saccharomyces cerevisiae|Phosphorylation|Cloning, Molecular|cDNA|Sequence Homology, Amino Acid|PtdIns|Protein Binding|Protein Isoforms|Kinetics | |
11279194 J. Biol. Chem. 2001 Animals|Humans|*trans-Golgi Network|*Na(+)-H(+)-Exchangers|*Cloning, Molecular|Antiporters|Amino Acid Sequence|Sodium|benzamil|Amiloride|Biological Transport|Sequence Homology, Amino Acid|Sequence Alignment | |
11280768 Cancer Res. 2001 Mice|Animals|Mice, Nude|*Molecular Weight|NM23 Nucleoside Diphosphate Kinases|ras-Related GTPases|Nucleoside-Diphosphate Kinase|Gene Expression Regulation, Neoplastic|Transcription Factors|Tumor Cells, Cultured|Transfection|Immunohistochemistry|Cell Division | |
11283017 J. Biol. Chem. 2001 Humans|Animals|Rats|lactotriaosylceramide|CDw17 antigen|*Lactosylceramides|*Glycolipids|lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase|*N-Acetylglucosaminyltransferases|*Epitopes|Phylogeny|*Rats, Inbred Lew|*Cloning, Molecular|FUT4 protein, human|*Fucosyltransferases|*Antigens, CD|*CD57 Antigens|Amino Acid Sequence|Substrate Specificity|Up-Regulation|Cell Line | |
11283257 Mol. Cell. Biol. 2001 PMC86908 *beta Karyopherins|*Leucine Zippers|*Sterol Regulatory Element Binding Protein 2|*Dimerization|*Helix-Loop-Helix Domain|*Cell Nucleus|Nuclear Localization Signals|Nuclear Proteins|Nuclear Import|Binding Sites|Amino Acid Sequence|Protein Binding|Sterol Regulatory Element Binding Protein 1|Gene Expression Regulation|Sequence Homology, Amino Acid|Sterols | |
11283606 Nat. Cell Biol. 2001 ROCK1 protein, human|*rho-Associated Kinases|*Apoptosis|Caspases|Caspase 3|Myosin Light Chains|Phosphorylation|DNA Fragmentation|Plasma Membrane|Actin|*Cell Death|*Proteolysis | |
11283721 Nat. Rev. Mol. Cell Biol. 2001 *Messenger RNA|RNA Stability|RNA Caps|Poly A|RNA Processing, Post-Transcriptional|Protein Biosynthesis|Half Life | |
11283793 Am. J. Hum. Genet. 2001 PMC1226089 Humans|Transaldolase Deficiency|*Transaldolase B|*Pentose Phosphate Pathway|Homozygote|Sequence Deletion|Carbohydrate Metabolism, Inborn Errors|arabitol|Sugar Alcohols|Ribitol|*Liver Cirrhosis|Metabolism, Inborn Errors|Sugar Phosphates|Erythritol | |
11284697 Biochemistry 2001 Humans|Caco-2 Cells|high density lipoprotein receptors|Lipoproteins, HDL|Scavenger Receptors, Class B|APOA1 protein, human|ApoA-I|CD36 Antigens|glucose-regulated proteins|high density lipoprotein binding protein|*RNA-Binding Proteins|Receptors, Immunologic|Lipoproteins, Low-Density|Cholesterol Esters|High Density Lipoprotein-3|Carrier Proteins|Binding Site|Protein Binding|Ligands | |
11285137 Traffic 2001 *Golgi Apparatus|Endoplasmic Reticulum|Vesicular Transport Proteins|SNARE Proteins|Golgi Matrix Proteins|rab1 GTP-Binding Proteins|Membrane Fusion|Carrier Proteins|Biological Transport|Saccharomyces cerevisiae Proteins|Small GTPases | |
11285224 EMBO J. 2001 PMC145469 Humans|*CD28 Antigens|*Down-Regulation|nef Gene Products, Human Immunodeficiency Virus|CD4 Antigens|HIV-1|Simian Immunodeficiency Virus|Endocytosis|T Cell Receptor|Receptor-CD3 Complex, Antigen, T-Cell|Histocompatibility Antigens Class I|Adaptor Protein Complex alpha Subunits|Jurkat Cells|Cell Membrane|Membrane Proteins|Adaptor Proteins, Vesicular Transport|Green Fluorescent Proteins|nef protein, Human immunodeficiency virus 2|nef protein, Human immunodeficiency virus 1 | |
11285228 EMBO J. 2001 PMC145457 *Neurotrophins|*Glutamate|*Signal Transduction Pathways|Phosphorylation|Phospholipase C gamma|Receptor, trkA|Enzyme Activation|Neurons|Tyrosine|Isoenzymes|Hippocampus | |
11285238 EMBO J. 2001 PMC145505 Animals|Nuclear Proteins|DNA-Binding Proteins|Membrane Proteins|*DNA|Thymopoietins|Cell Nucleus|Amino Acid Sequence|Isoforms|Protein Binding|Sequence Homology, Amino Acid|Xenopus laevis | |
11285266 J. Biol. Chem. 2001 Chlorocebus aethiops|Animals|Humans|*Phosphoinositide Kinase|HEK293 Cells|phosphatidylinositol 5-phosphate|Phosphatidylinositol Phosphates|*Homeostasis|Phosphatidylinositol 3-Kinases|Endosomes|COS Cells|Endocytosis|Cell Membrane|Vacuoles|*B-Lymphocytes|*Membrane|Transfections|*Mammals|Phosphatidylinositol|Phosphorylation|PIKFYVE protein, human | |
11285270 J. Cell Biol. 2001 PMC2185522 *Chlamydomonas|*Flagella|kinesin-II|Kinesin|Dyneins|TYRP1 protein, human|*Membrane Glycoproteins|Biological Transport|Protein Transport|Protozoan Proteins|Mutations|Basal Bodies | |
11285280 J. Cell Biol. 2001 PMC2185534 Humans|*Anaphase-Promoting Complex-Cyclosome|*Cyclin|*Anaphase|*M Phase Cell Cycle Checkpoints|*Proteolysis|*Mitosis|Cell Cycle Proteins|Cyclin B1|Spindle Apparatus|Cdc20 Proteins|Metaphase|*Proliferating Cell Nuclear Antigen|Cyclin A|Ubiquitin-Protein Ligases | |
11287605 Mol. Cell. Biol. 2001 PMC86928 Mice|Animals|*Liver X Receptors|SREBF1 protein, human|*Sterol Regulatory Element Binding Protein 1c|*Retinoid X Receptors|Orphan Nuclear Receptors|Response Element|Promoter Regions, Genetic|Receptors, Retinoic Acid|oxysterol binding protein|Receptors, Steroid|CCAAT-Enhancer-Binding Proteins|Fatty Acids|Hydroxycholesterols|Lipid Metabolism|Liver|Cell Nucleus | |
11287626 Mol. Cell. Biol. 2001 PMC86965 Humans|Mice|Animals|*Nucleosomes|*Hepatocyte Nuclear Factor 1-alpha|Nuclear Proteins|Hepatocyte Nuclear Factor 1|Promoter Regions, Genetic|Homeodomain Proteins|Hepatocyte Nuclear Factor 1-beta|Trans-Activators|Pancreatic Islet|Transcription, Genetic|Pancreas|Binding Sites|Liver|Base Sequence|Hepatocytes|Insulin | |
11289114 Cancer Res. 2001 *Leukemia, Erythroblastic, Acute|*Phosphorylation|Erythropoietin Receptor|STAT5B protein, human|Signal Transducer and Activator of Transcription 5A|EPO protein, human|Erythropoietin|JAK2 protein, human|Janus Kinase 2|STAT5A protein, human|Erythroid Precursor Cells|Cell Differentiation|Signal Transduction|src-Family Kinases|Erythropoiesis|*Cells, Erythroid|GATA1 protein, human|GATA1 Transcription Factor | |
11289803 Virology 2001 *Active Transport, Cell Nucleus|*Ribonucleoproteins|*Cell Nucleus|*Orthomyxoviridae|Cytoplasm|Influenza A virus|Viral Matrix Proteins|Viral Nonstructural Proteins|Virus Replication|Cell Line | |
11290324 Cell 2001 *Neural Tube|Transcription Factors|Proteins, Homeo Domain|Basic Helix-Loop-Helix Transcription Factors|Repressor Proteins|Drosophila Proteins|*Neurons|Gene Expression Regulation, Developmental|*Gene Expression|Amino Acid Sequence|Protein Binding|*Progenitor Cell | |
11290418 Gene 2001 Humans|RANGNRF protein, human|ran GTP-Binding Protein|Nuclear Protein|Saccharomyces cerevisiae|Saccharomyces cerevisiae Proteins|Cell Nucleus|Transport, Nuclear|Amino Acid Sequence|Two-Hybrid System Techniques|Protein Binding|Protein Transport|Guanine Nucleotide Exchange Factors|Sequence Homology, Amino Acid|GSP1 protein, S cerevisiae|Monomeric GTP-Binding Proteins | |
11290583 Blood 2001 *Receptors, Erythropoietin|*STAT5 Transcription Factor|*Phosphorylation|JAK2 protein, human|Janus Kinase 2|EPO protein, human|Erythropoietin|SH2 Domain|Signal Transduction|Trans-Activators|DNA-Binding Proteins|Protein Binding|Tyrosine|Cell Lines|Cell Division|*Epitopes | |
11290605 Blood 2001 Humans|Mice|Animals|FGFR3 protein, human|*Receptor, Fibroblast Growth Factor, Type 3|*Multiple Myeloma|*Oncogene|Translocation, Genetic|Cell Transformation, Neoplastic|Gene Expression Regulation, Neoplastic|Lymphoma|Mutation|Carrier Proteins|Cell Cycle|Tumor Cells, Cultured|Hematopoietic Stem Cell Transplantation | |
11292825 J. Biol. Chem. 2001 PMC1364467 Cattle|Animals|Mice|*Rod Cell Outer Segment|*Phosphorylation|*Protein Kinase|GRK1 protein, human|Kinase, Rhodopsin|Rhodopsin|RGS Proteins|Eye Proteins|Protein Kinase A|Amino Acid Sequence|Retina|Serine|Kinetics|Light|Cell Membrane|G Protein | |
11292842 Nucleic Acids Res. 2001 PMC31313 Humans|MLH1 protein, human|MutL Protein Homolog 1|Mismatch Repair Endonuclease PMS2|DNA Repair Enzymes|MutL Proteins|DNA-Binding Proteins|Adenosine Triphosphatases|Nuclear Proteins|Base Pair Mismatch|DNA Repair|Carrier Proteins|Neoplasm Proteins|Adaptor Proteins, Signal Transducing|*Dimerization|*Amino Acids | |
11292861 Science 2001 Humans|*Hydroxylation|VHL protein, human|Von Hippel-Lindau Tumor Suppressor Protein|Transcription Factors|DNA-Binding Proteins|*Ubiquitylation|Nuclear Proteins|*Oxygen|Procollagen-Proline Dioxygenase|Trans-Activators|Ubiquitins|Hypoxia|Ligases|Amino Acid Sequence|Activation, Transcriptional|Protein Binding | |
11292862 Science 2001 Humans|Animals|VHL protein, human|*Von Hippel-Lindau Tumor Suppressor Protein|*Hydroxylation|*Proline|Transcription Factor|Nuclear Proteins|Trans-Activators|Protein Structure, Tertiary|Ligases|Basic Helix-Loop-Helix Transcription Factors|Amino Acid Sequence|Protein Binding|Oxygen|Peptides | |
11294240 Pflugers Arch. 2001 ROCK1 protein, human|*rho-Associated Kinases|*Arachidonic Acid|*Calcium|*Muscle Contraction|Myosin Phosphatase|Myosin Light Chain Kinase|Y 27632|Amides|RHOA protein, human|rhoA GTP-Binding Protein|Phosphorylation|Pyridines|Muscle, Smooth, Vascular|Triton X-100|Type C Phospholipases|Guanosine 5'-O-(3-Thiotriphosphate) | |
11294880 J. Biol. Chem. 2001 Humans|Female|potassium-dependent sodium-calcium exchanger|*Na(+)-Ca(2+) Exchanger|*Cloning, Molecular|Potassium|Amino Acid Sequence|Uterus|Calcium|Signal Sequence | |
11294897 Mol. Biol. Cell 2001 PMC32277 Humans|Mice|Animals|FGFR3 protein, human|*Receptor, Fibroblast Growth Factor, Type 3|*Phosphorylation|*Tyrosine|Signal Transduction|STAT1 protein, human|STAT1 Transcription Factor|STAT3 protein, human|STAT3 Transcription Factor|PTPN11 protein, human|Protein Tyrosine Phosphatase, Non-Receptor Type 11|Mitogen-Activated Protein Kinases|Phosphatidylinositol 3-Kinases|Cell Transformation, Neoplastic|Trans-Activators|3T3 Cells | |
11294908 Mol. Biol. Cell 2001 PMC32288 *Importin|*Active Transport, Cell Nucleus|*Transforming Growth Factor beta|SMAD3 protein, human|*Smad3 Protein|*ran GTP-Binding Protein|SMAD2 protein, human|Smad2 Protein|Transforming Growth Factor beta Receptor|Cell Nucleus|Nuclear Proteins|Signal Transduction|Trans-Activators|Receptor, Transforming Growth Factor-beta Type I|Phosphorylation|TGFBR2 protein, human|Receptor, Transforming Growth Factor-beta Type II|Smad Proteins | |
11296240 EMBO J. 2001 PMC125234 *Catalytic Domain|*Influenza, Human|RNA Replicase|Influenza Viruses|RNA Caps|*Endonucleases|Viral Proteins|RNA, Viral|RNA primers|Cap Binding Proteins|Sequences, Amino Acid|Transcription, Genetic|Virion | |
11296245 Proc. Natl. Acad. Sci. U.S.A. 2001 PMC33162 Animals|*Drosophila|Drosophila Proteins|Drosophila melanogaster|Body Patterning|Serine Endopeptidases|Enzyme Precursors|Signal Transduction|Embryonic Development|Enzyme Activation|*Embryo, Mammalian|Sulfotransferases|Gastrulation | |
11296286 Proc. Natl. Acad. Sci. U.S.A. 2001 PMC31843 Humans|Mice|Animals|*Receptors, Erythropoietin|EPO protein, human|*Erythropoietin|*Protein Binding|*Epoetin Alfa|*Ligands|*Receptors, Cell Surface|Signal Transduction|Amino Acid Sequence|Cell Membrane|Dimerization|Phosphorylation|Tyrosine Kinase Receptors|Cytoplasm|*Protein Domains|*Protein Transport|Cell Line | |
11297515 J. Biol. Chem. 2001 Kinetics|Computer Simulation|*Thromboxane-A Synthase|Prostaglandin H2|*Catalysis|Protein Binding|Substrate Specificity|Binding Sites|Ligands|Cytochrome P450|Amino Acid Sequence|Haem|Oxidation-Reduction|U 44069|Prostaglandin Endoperoxides, Synthetic|Thromboxanes | |
11297558 J. Biol. Chem. 2001 Animals|Chlorocebus aethiops|*Epidermal Growth Factor|*Consensus|ADGRE5 protein, human|*Antigens, CD|*CD55 Antigens|*Receptors, G-Protein-Coupled|*Amino Acid Motifs|Membrane Glycoproteins|Protein Binding|Amino Acid Sequence|Cell Membrane|COS Cells|Biotinylations|*Protein Domains|DNA, Complementary | |
11297579 J. Clin. Endocrinol. Metab. 2001 Humans|Male|Female|*Kallmann Syndrome|Idiopathic Hypogonadotropic Hypogonadism|Hypogonadism|*Genotype-Phenotype Correlations|Phenotype|Gn-RH|Pedigree|Mutation|Anosmia|DNA Mutational Analysis|Heterozygote|Amino Acid Sequence | |
11298456 Nature 2001 Humans|CDC25A protein, human|*cdc25 Phosphatases|CDS1 Kinase|Phosphorylation|DNA Damage|Ataxia Telangiectasia Mutated Proteins|DNA Replication|CDK2 protein, human|Cyclin-Dependent Kinase 2|Cell Cycle|Protein Kinases|Tumor Suppressor Proteins|Ionizing Radiation|S Phase|DNA-Binding Proteins|Checkpoint Kinase 1|Nuclear Proteins|Ataxia-Telangiectasia | |
11301004 Cell 2001 Humans|Animals|*Drosophila|*Cell Polarity|*rho-Associated Kinases|*Cell Signaling|Drosophila Proteins|Wings, Animal|Frizzled Receptors|Adaptor Proteins, Signal Transducing|Dishevelled Proteins|Phosphoproteins|*Actin Cytoskeleton|Photoreceptor Cells, Invertebrate|Phosphorylation|Receptors, G-Protein-Coupled|Membrane Proteins|Actin|dsh protein, Drosophila | |
11301010 Cell 2001 Humans|BRCA1 protein, human|*BRCA1 Protein|*DNA Repair|RTEL1 protein, human|*DNA Helicases|Fanconi Anemia Complementation Group Proteins|DNA-Binding Proteins|Transcription Factors|Basic-Leucine Zipper Transcription Factors|Mutations, Germline|Nuclear Proteins|RNA Helicases|Mutation|Protein Binding|BACH1 protein, human | |
11301334 J. Biol. Chem. 2001 Humans|*K562 Cells|*Leukemia, Erythroblastic, Acute|zinc-binding protein|Zinc|Cation Transport Proteins|mRNA|Biological Transport|*Ion Transport|Plasma Membrane | |
11301410 Med Res Rev 2001 cyclopentenone|*Prostaglandins B|*Cyclopentane|Prostaglandins|15-deoxyprostaglandin J2|Prostaglandin D2|Receptors, Cytoplasmic and Nuclear|Apoptosis|Transcription Factors|prostaglandin A2|Prostaglandins A|Ligands|Receptors, Prostaglandin|Signal Transduction|Anti-Inflammatory Agents | |
11302699 Exp. Cell Res. 2001 Humans|Animals|Chlorocebus aethiops|*Phosphate|*Phosphoprotein Phosphatases|Protein Tyrosine Phosphatases|Amino Acid Sequence|Protein Tyrosine Phosphatases, Non-Receptor|Substrate Specificity|Cloning, Molecular|Phosphatidylinositol Phosphates|Sequence Homology, Amino Acid|*Biochemical Phenomena|DNA, Complementary|COS Cells|Caenorhabditis elegans|nitrophenylphosphate|Nitrophenols|Organophosphorus Compounds | |
11302742 Biochem. Biophys. Res. Commun. 2001 Humans|Xanthinuria, Type I|Xanthinuria, Type II|*Xanthine Dehydrogenase|*Aldehyde Oxidase|MOCOS protein, human|*Sulfurtransferases|*Purine-Pyrimidine Metabolism, Inborn Errors|*Xanthine|molybdenum cofactor|Pteridines|Coenzymes|Metalloproteins|*Mutation|Metabolism, Inborn Errors|Codon | |
11303027 J. Biol. Chem. 2001 Humans|Animals|*ADP-Ribosylation Factors|*Binding Proteins|Golgi Apparatus|Membrane Proteins|Brefeldin A|Autoantigens|Amino Acid Sequence|Guanine Nucleotide Exchange Factors|ARL2 protein, human|GTP-Binding Proteins | |
11304796 J. Histochem. Cytochem. 2001 Humans|*N-Acetylglucosaminyltransferases|Gastric Mucosa|Mucin-6|Stomach Neoplasms|Mucin 5AC|Adenocarcinoma|MUC1 protein, human|Mucin-1|Immunohistochemistry|Brunner Glands|cDNA|Cloning, Molecular|Polysaccharides|*Gastrointestinal Tract | |
11305939 Genome Biol. 2001 PMC31480 Humans|*Sodium-Bicarbonate Symporters|Sequence Alignment|Base Sequence|Amino Acid Sequence|DNA, Complementary|Introns|Cloning, Molecular|Chromosome Mapping|Exons|Alternative Splicing|Blotting, Northern|Sequence Analysis, DNA|Gene Expression|RNA, Messenger|Sequence Homology, Amino Acid|*Chromosome Structures|Phylogeny | |
11306053 Chem. Biol. Interact. 2001 Humans|Mice|Animals|long-chain-aldehyde dehydrogenase|*Aldehyde Oxidoreductases|Sjogren-Larsson Syndrome|*DNA Mutational Analysis|Exons|Mutations|Amino Acid Sequence|Alternative Splicing|Mutations, Missense|*Computational Biology|Genomics | |
11306453 Cancer Res. 2001 Rats|Male|Animals|Humans|*MAP Kinase Kinase 4|*Prostatic Cancers|Genes, Tumor Suppressor|Mitogen-Activated Protein Kinase Kinases|*Neoplastic Processes|Prostate|Loss of Heterozygosity|Gene Expression Regulation, Neoplastic|Tumor Cells, Cultured|Downregulation|Signal Transduction|Allele | |
11306517 Cell Growth Differ. 2001 Humans|Mice|Animals|IL9 protein, human|*Interleukin-9|*Transcriptional Activation|IL9R protein, human|*Receptor, Interleukin-9|STAT3 protein, human|STAT3 Transcription Factor|STAT1 protein, human|STAT1 Transcription Factor|Trans-Activators|STAT5 Transcription Factor|Signal Transduction|Phosphorylation|*Growth Inhibitors|Cell Division|Interleukin|Lymphomas | |
11306556 EMBO Rep. 2001 PMC1083862 Humans|Rats|Animals|*Golgi Matrix Proteins|Golgi Apparatus|Membrane Proteins|Carrier Proteins|Vesicular Transport Proteins|Protein Binding|Binding Sites|Autoantigens|Amino Acid Sequence|Cell Line|Monomeric GTP-Binding Proteins|Rab1B protein, human|rab1 GTP-Binding Proteins | |
11306702 Mol. Pharmacol. 2001 Humans|*Uridine Cytidine Kinase|*Nucleosides|*Phosphorylation|N-acetylcytidine|*Cytidine|5-methylcytidine|5-fluorocytidine|2-thiocytidine|5-fluorouridine|*Uridine|5-bromouridine|mRNA|Cell Line, Tumor|cDNA | |
11309201 J. Cell. Sci. 2001 Rats|Animals|*Synaptotagmin|*Insulin|*Exocytosis|*Isoforms|Calcium-Binding Proteins|*Insulin, Regular, Human|Pancreatic Islet|Nerve Tissue Proteins|*Endocrine Cells|Insulin-Secreting Cells|Membrane Glycoproteins|Recombinant Proteins|Calcium|PC12 Cells|streptolysin O|Bacterial Proteins|Streptolysins | |
11309290 Cancer Res. 2001 Animals|Humans|triphosphoric acid|*ATP-Binding Cassette Transporters|*Membrane Transport Proteins|*Adenosine Triphosphate|Estramustine|cDNA|Cloning, Molecular|Amino Acid Sequence|RNA, Messenger|Transfections|Tumor Cell Lines|Brain|Adenosine | |
11310843 J. Leukoc. Biol. 2001 Cricetinae|Animals|*Scavenger Receptors, Class A|*Macrophage|*Collagen|Receptors, Immunologic|Scavenger Receptors, Class B|Cell Adhesion|Ligands|Protein Binding|Transfection|CHO Cells|*Tissue Adhesions | |
11313316 Gastroenterology 2001 Humans|Adult|*Gallbladder|*Cholelithiasis|ATP Binding Cassette Transporter, Subfamily B|Bile|Liver|ATP-Binding Cassette Transporters|Phenotype|Phospholipids|Cholecystolithiasis|Cholestasis|Cholesterol|Mutation | |
11313345 J. Biol. Chem. 2001 GJA1 protein, human|*Connexin 43|*Tight Junctions|connexin 45|*Connexins|Gap Junctions|Zonula Occludens-1 Protein|Phosphoproteins|Cell Communication|Protein Transport|Protein Binding|Osteoblasts|Immunofluorescence | |
11313357 J. Biol. Chem. 2001 Animals|Rats|*Receptors, Purinergic P2X7|Purinoceptors, P2X|3'-O-(4-benzoyl)benzoyladenosine 5'-triphosphate|Adenosine Triphosphate|Glia|Astrocytes|Protein Subunits|Cell Line|*Brain|Peritoneal Macrophage | |
11313359 J. Biol. Chem. 2001 Mice|Animals|*Bone Morphogenetic Protein 1|*Protein-Lysine 6-Oxidase|*Metalloproteinases|Tolloid-Like Metalloproteinases|Bone Morphogenetic Proteins|Metalloendopeptidases|Collagen|Extracellular Matrix|Procollagen|Fibroblasts|*Mammals|Homozygote|Cells, Cultured | |
11313366 J. Biol. Chem. 2001 Humans|Mice|Animals|Spores, Bacterial|ITLN1 protein, human|*Cytokines|*GPI-Linked Proteins|Amino Acid Sequence|Xenopus laevis|Xenopus Proteins|Cloning, Molecular|Lectins, C-Type|*Cell Wall|Sequence Homology, Amino Acid|Galactose|*Carbohydrate|Protein Binding|mRNA|*Bacteria | |
11313498 Science 2001 *RNA Polymerase II|Protein Conformation|Saccharomyces cerevisiae|Transcription, Genetic|Protein Structure, Tertiary|Protein Structure, Secondary|Binding Sites|Crystallography, X-Ray|Protein Structure, Quaternary|DNA, Fungal|Promoter Regions, Genetic|Models, Molecular|Templates, Genetic|Crystallization|RNA, Messenger|RNA | |
11313499 Science 2001 *RNA Polymerase II|Protein Conformation|Binding Site|Transcription, Genetic|Nucleic Acid Conformation|Protein Structure, Tertiary|RNA|Crystallography, X-Ray|Base Pairs|Templates, Genetic|Models, Molecular|Saccharomyces cerevisiae|DNA|Nucleic Acid Hybridization|Promoter Regions, Genetic|RNA, Messenger | |
11313909 Oncogene 2001 *Signal Transduction|GTP-Binding Protein alpha Subunits, Gi-Go|Heterotrimeric GTP-Binding Proteins|GTP-Binding Protein alpha Subunits, Gq-G11|Pertussis Toxin|Protein Binding|Receptors, Cell Surface|Carrier Proteins|Cell Differentiation | |
11313932 Oncogene 2001 Humans|*Active Transport, Cell Nucleus|*14-3-3 Proteins|cdc25 Phosphatase|CDC2 Protein Kinase|*Protein Binding|Mitosis|Cell Nucleus|Cytoplasm|Phosphorylation|Interphase|Cyclin B|Phosphoprotein Phosphatases|Amino Acid Sequence|Protein Transport|CDC25C protein, human | |
11313946 Oncogene 2001 Animals|Mice|*p21(ras)|Proto-Oncogene Proteins|DNA-Binding Proteins|Transcription Factors|Mitogen-Activated Protein Kinases|Proto-Oncogene Proteins c-raf|Guanine Nucleotide Exchange Factors|Phosphorylation|ralGDS|*Cell Cycle|Protein Binding|3T3 Cells | |
11313965 Oncogene 2001 Rats|Animals|CASP3 protein, human|*Caspase 3|geranylgeranyltransferase type-I|*Farnesyltranstransferase|p21(ras) farnesyl-protein transferase|N-acetyl-tyrosyl-valyl-alanyl-aspartyl chloromethyl ketone|Amino Acid Chloromethyl Ketones|Caspase Inhibitors|Caspases|*Apoptosis|*Farnesyl-Diphosphate Farnesyltransferase|Etoposide|Cysteine Proteinase Inhibitors|Transferases|Cell Line|Tumor Cells, Cultured | |
11316748 Endocrinology 2001 Mice|Animals|*Insulin Like Growth Factor I Receptor|IRS4 protein, human|*Insulin Receptor Substrate Proteins|IGF1 protein, human|*Insulin-Like Growth Factor I|IGF1R protein, human|*Receptors, Somatomedin|INSR protein, human|Insulin Receptor|Phosphorylation|Proto-Oncogene Proteins c-crk|Signal Transduction|SH2 Domain|Phosphoproteins|Protein Kinases|Tyrosine|Proto-Oncogene Proteins|3T3 Cells | |
11316767 Endocrinology 2001 Animals|Humans|Rats|Phylogeny|*Biological Transport|Organic Anion Transporters|Thyroid Hormones|Messenger RNA|Amino Acid Sequence|Anion Transport Proteins|Carrier Proteins|Complementary DNA|Brain|Liver | |
11316783 Endocrinology 2001 IGFBP5 protein, human|*Insulin-Like Growth Factor Binding Protein 5|*Amino Acids, Basic|IGFBP3 protein, human|Insulin-Like Growth Factor Binding Protein 3|Insulin-Like Growth Factor Binding Protein 6|Protein Binding|Binding Sites|Insulin-Like Growth Factor I|Amino Acid Sequence|*Mutagenesis|Phosphorylation|Signal Transduction|Mutation|Sequence Homology, Amino Acid | |
11318953 Kidney Int. 2001 Humans|*Cystinuria|Amino Acid Transport Systems, Basic|Cystine|*Membrane Transport Proteins|Carrier Proteins|Biological Transport|Membrane Glycoproteins|Tubules, Proximal Renal|Amino Acid Sequence|Kidney|Cell Membrane|Transfection | |
11322507 Endocrine 2001 Humans|*Receptors, Ghrelin|*Ligands|HEK293 Cells|GPRC5C protein, human|Receptors, Cell Surface|Ghrelin|Growth Hormone-Releasing Hormone|ibutamoren mesylate|Spiro Compounds|Growth Hormone|Amino Acid Sequence|gamma-aminobutyryl-2-methyltryptophyl-2-methyltryptophyl-2-methyltryptophyl-lysinamide|Oligopeptides|Cloning, Molecular|Indoles | |
11322953 FEBS Lett. 2001 Humans|*Acetylgalactosamine|*Substrate Specificity|UDP-galactose translocator|*Monosaccharide Transport Proteins|SLC35D1 protein, human|UDP Glucuronic Acid|Uridine Diphosphate N-Acetylgalactosamine|Uridine Diphosphate Galactose|Biological Transport|Nucleotide Transport Proteins|Microsomes|Uridine Diphosphate N-Acetylglucosamine|Golgi Apparatus|Membrane Transport Proteins|Saccharomyces cerevisiae|Amino Acid Sequence|Glucuronic Acid|Sugars | |
11323407 J. Biol. Chem. 2001 Humans|mitochondrial ferritin, human|*Ferritin|*Mitochondrial Proteins|Iron|Mitochondria|Erythroblasts|Amino Acid Sequence|Cytoplasm|Homeostasis | |
11323411 J. Biol. Chem. 2001 *Phosphotyrosine|GRB2 protein, human|*GRB2 Adaptor Protein|Phosphoproteins|Epidermal Growth Factor|Protein Tyrosine Phosphatase, Non-Receptor Type 11|SH2 Domains|Signal Transduction|Enzyme Activation|MAPK1 protein, human|Mitogen-Activated Protein Kinase 1|Phosphorylation|MAP Kinase Signaling System|Extracellular Signal Regulated Kinases|Protein Binding|Tyrosine | |
11323433 J. Biol. Chem. 2001 Humans|ORC5 protein, human|ORC6 protein, human|ORC1 protein, human|*Origin Recognition Complex|HeLa Cells|Replication Origin|DNA Replication|Chromatin|Saccharomyces cerevisiae|Protein Binding|Baculovirus|Cell Nucleus|Cloning, Molecular|ORC5 protein, S cerevisiae|Saccharomyces cerevisiae Proteins | |
11323434 J. Biol. Chem. 2001 Animals|MAP kinase kinase kinase 7|Caenorhabditis elegans|*MAP Kinase Kinase Kinases|TAB1 protein, human|Adaptor Proteins, Signal Transducing|Signal Transduction|Phosphorylation|Intracellular Signaling Peptides and Proteins|Mitogen-Activated Protein Kinases|Binding Protein|Enzyme Activation|Protein Binding|Cell Line|Amino Acid Sequence|Transfection | |
11323673 Nature 2001 Mice|Animals|TLR5 protein, human|*Toll-Like Receptor 5|*Flagellin|Anti-Bacterial Agents|Gram-Positive Bacteria|Gram Negative Bacteria|Toll-Like Receptors|MyD88 Protein|*Innate Immune Response|Receptors, Immunologic|Nuclear Factor-Kappab|Toll-Like Receptor 2|Membrane Glycoproteins|Toll-Like Receptor 4|Adaptor Proteins, Signal Transducing|Signal Transduction|Antigens, Differentiation|Lipopolysaccharides | |
11323713 Nat. Struct. Biol. 2001 *Transformylase|IMP cyclohydrolase|Nucleotide Deaminases|AICA ribonucleotide|Ribonucleotides|AICARTFase|Aminoimidazole Carboxamide|purine|*Purines|Protein Conformation|Multienzyme Complexes|Crystallography, X-Ray|Binding Sites|Sites, Active|Models, Molecular|Kinetics | |
11325826 Cancer Res. 2001 BRAF protein, human|*Proto-Oncogene Proteins B-raf|Proto-Oncogene Proteins c-raf|*MAP Kinase Signaling System|ras Proteins|*Dimerization|Signal Transduction|*Proto-Oncogene Proteins|Isoforms|Mutation|Cell Line, Tumor|Binding Sites | |
11325957 J. Biol. Chem. 2001 Humans|CHUK protein, human|*I-kappa B Kinase|*tax Protein|*NF-kappa B|*Phosphorylation|Human T-lymphotropic virus 1|Signal Transduction|I-kappa B Proteins|RELA protein, human|Transcription Factor RelA|Enzyme Activation|Protein Binding|Jurkat Cells|Transfections|Mutation|Multienzyme Complexes | |
11326272 Nat. Genet. 2001 Mice|Humans|Animals|Schwartz-Lelek syndrome|*Hyperostosis|*Hypertelorism|Dysplasia, Bone|Craniofacial Abnormalities|*Heterozygote|*Mutations|Phosphate Transport Proteins|DNA Mutational Analysis|*Ankylosis|Skull|Sequence Deletion|Bone Mineralization|Membrane Proteins|ANKH protein, human | |
11326280 Nat. Genet. 2001 Humans|*Glycosylation|Congenital disorder of glycosylation, type 2C|*Congenital Disorders of Glycosylation|*Fucose|GDP Fucose|Golgi Apparatus|Leukocyte-Adhesion Deficiency Syndrome|Monosaccharide Transport Proteins|*Complement Factor B|Glycoproteins|Glycans|Fibroblasts|Mutations|Cloning, Molecular | |
11326338 Am. J. Hum. Genet. 2001 PMC1226118 Craniometaphyseal Dysplasia, Autosomal Dominant|*Craniomandibular Disorders|Schwartz-Lelek syndrome|Hyperostosis|Bone Diseases, Developmental|Hypertelorism|*Mutations|*Membrane Proteins|Phosphate Transport Proteins|Craniofacial Abnormalities|Genetic Linkage|DNA Mutational Analysis|Pedigree|Amino Acid Sequence|Skull | |
11327718 Biochem. Biophys. Res. Commun. 2001 Humans|Animals|Rats|*Organic Anion Transporters|p Aminohippurate|Organic Anion Transporters, Sodium-Independent|*Kidney|Carrier Proteins|Biological Transport|Cloning, Molecular|Xenopus laevis|cDNA|Amino Acid Sequence|Anion Transport Proteins|Tissue Distribution|Blotting, Northern|*Liver|Oocytes|RNA, Messenger | |
11327815 Biochemistry 2001 Humans|maleylacetoacetate isomerase|*Glutathione Transferase|*cis-trans-Isomerases|*Catalysis|Glutathione|Amino Acid Sequence|Tyrosine|Binding Sites|Crystallography, X-Ray|Dimerization|Sequence Alignment|Phenylalanine|Models, Molecular|Isomerism | |
11328811 J. Biol. Chem. 2001 Animals|Humans|Rabbits|*Gated Channel, Cyclic-Nucleotide|*Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels|*Sinoatrial Node|Potassium Channels|Patch-Clamp Techniques|Muscle Proteins|Isoforms|*Pacemaker, Artificial|Amino Acid Sequence|Electrophysiological Phenomena|Nerve Tissue Proteins|mRNA | |
11328862 Mol. Endocrinol. 2001 Humans|Tec protein-tyrosine kinase|*Receptors, Prolactin|*Tyrosine Kinase|VAV1 protein, human|*Proto-Oncogene Proteins c-vav|*Protein Binding|*Binding Site|Signal Transduction|Proto-Oncogene Proteins|Cell Cycle Proteins|Phosphorylation|Ligands|Tyrosine | |
11329366 J. Cell. Sci. 2001 *WAVE Proteins|WASL protein, human|Wiskott-Aldrich Syndrome Protein, Neuronal|*Actin Cytoskeleton|Microfilament Proteins|*Cell Movement|Actin-Related Protein 2|Actin-Related Protein 3|Actins|Filopodia|BAIAP2 protein, human|Nerve Tissue Proteins|Arp2-3 Complex|Wiskott-Aldrich Syndrome|Amino Acid Sequence|Protein Binding | |
11330046 Cell Biochem. Biophys. 2001 Rats|Mice|Animals|*Peroxisome Proliferator-Activated Receptors|Receptors, Nuclear|Peroxisome Proliferators|9-cis-Retinoic Acid Receptor|Peroxisomes|Transcriptional Activation|Lipid Metabolism|Microbodies|Oxidase, Fatty Acyl-CoA|Promoter Regions, Genetic|Cell Nucleus|Hepatocytes|Oxidation-Reduction|Liver|Fatty Acids|Gene Expression Regulation, Enzymologic|Signal Transduction|Oxidoreductases | |
11331269 J. Biol. Chem. 2001 Animals|Humans|Caenorhabditis elegans|SMG1 protein, human|*Phosphatidylinositol 3-Kinases|Phosphorylation|*RNA Stability|Protein Kinases|cDNA|Amino Acid Sequence|Cloning, Molecular|RNA, Messenger|Sequence Homology, Amino Acid|Phosphatidylinositols|SMG-1 protein, C elegans|Protein-Serine-Threonine Kinases|Caenorhabditis elegans Proteins | |
11331307 J. Cell Biol. 2001 PMC2190572 ROCK1 protein, human|*rho-Associated Kinases|*Stress Fibers|Myosin Regulatory Light Chain|Myosin-Light-Chain Kinase|Myosin-Light-Chain Phosphatase|Phosphorylation|Calmodulin|rho GTP-Binding Proteins|Actins|Focal Adhesions|Cell Motility|Muscle Contraction|Muscle, Smooth|Calcium|Cultured Cells | |
11331308 J. Cell Biol. 2001 PMC2190577 Humans|*Focal Adhesions|integrin-linked kinase|*Cell Adhesion|*Protein A|*Protein-Serine-Threonine Kinases|LIM Domain Proteins|Adaptor Proteins, Signal Transducing|DNA-Binding Proteins|Protein Binding|Carrier Proteins|Membrane Proteins|Microfilament Proteins|Actinin|Cytoskeleton|Cell Movement|Integrins|Extracellular Matrix|Cell Line | |
11331872 Nat. Cell Biol. 2001 Rats|Animals|CDK5 protein, human|*Cyclin-Dependent Kinase 5|EGR1 protein, human|*Transcription Factor, EGR1|Signal Transduction|NGF protein, human|Nerve Growth Factor|*Neurons|PC12 Cells|Cell Differentiation|Phosphorylation|Extracellular Signal Regulated Kinases|Neurites|Immediate-Early Proteins|Chromones|Egr1 protein, rat | |
11333016 RNA 2001 PMC1370092 *snRNA|exportin 1 protein|Karyopherins|*RNA Recognition Motif|*RNA-Binding Domain|Nucleocytoplasmic Transport Proteins|Cell Nucleus|Receptors, Cytoplasmic and Nuclear|Cytoplasm|Phosphoproteins|Spliceosomes|RNA|Phosphorylation|Amino Acid Sequence | |
11333026 RNA 2001 PMC1370102 Humans|*RNA Precursors|*RNA Splicing|Spliceosomes|Ribonucleoproteins, Small Nuclear|Introns|RNA, Small Nuclear|Exons|Cell Nucleus|Base Sequence|Nuclear Proteins|HeLa Cells | |
11333915 J. Virol. 2001 PMC114939 *Hepatitis B virus|*Clathrin|Adaptor Protein Complex gamma Subunits|Binding Sites|TYRP1 protein, human|*Membrane Glycoproteins|Membrane Proteins|Carrier Proteins|Amino Acid Sequence|Viral Envelope Proteins|*Adaptor Proteins, Signal Transducing|Protein Binding|Transfections|Viral Particles|Golgi Apparatus|Cytosol | |
11336508 Dev. Biol. 2001 Mice|Animals|Homeodomain Proteins|Transcription Factors|Binding Sites|Enhancer Elements, Genetic|Rhombencephalon|Body Patterning|Gene Expression Regulation, Developmental|Base Sequence|Mice, Transgenic|Conserved Sequence|Early Growth Response Protein 2|Sequence Homology, Nucleic Acid|Vertebrates|*Neurogenesis | |
11336673 Cell 2001 *Growth Cones|*EphA Receptors|RHOA protein, human|rhoA GTP-Binding Protein|rho GTPases|RASGRF1 protein, human|*ras-GRF1|Rho Guanine Nucleotide Exchange Factors|rac1 GTP-Binding Protein|Signal Transduction|Actin|Neurons|Cell Movement|Cells, Cultured | |
11336703 Mol. Cell 2001 *Axin Protein|*Wnt Signaling Pathway|LRP5 protein, human|*Low Density Lipoprotein Receptor-Related Protein-5|CTNNB1 protein, human|beta Catenin|Wnt Proteins|Phosphoproteins|Adaptor Proteins, Signal Transducing|LEF1 protein, human|Lymphoid Enhancer-Binding Factor 1|Dishevelled Proteins|Repressor Proteins|Calcium-Calmodulin-Dependent Protein Kinases|Proto-Oncogene Proteins|Trans-Activators|Zebrafish Proteins|Carrier Proteins | |
11337497 J. Biol. Chem. 2001 PMC2025680 Humans|Female|*Interferon-beta|inositol hexakisphosphate kinase|*Carcinoma, Ovarian Epithelial|Phosphotransferases (Phosphate Group Acceptor)|*Ovarian Neoplasms|Apoptosis|Cell Cycle|Cell Line, Tumor|Gene Expression Regulation, Neoplastic|Interferon | |
11340051 Annu Rev Biophys Biomol Struct 2001 *Protons|*Mitochondria|Electron Transport|Cell Respiration|Electron Transport Complex I|Inner Mitochondrial Membrane|Oxidative Phosphorylation|Electron Transport Complex IV|Succinate Dehydrogenase|NADH, NADPH Oxidoreductases|Multienzyme Complexes|Thermodynamics|Models, Molecular | |
11340066 J. Biol. Chem. 2001 Humans|Chlorocebus aethiops|Dogs|Animals|Sucrase-isomaltase deficiency, congenital|Sucrase-Isomaltase Complex|Carbohydrate Metabolism, Inborn Errors|*Intestines|*Intestinal Diseases|Protein Transport|Golgi Apparatus|Amino Acid Sequence|Protein Folding|Point Mutation|Mutation|Glycosylation|COS Cells|Isomaltase|Cell Membrane|Phenotype | |
11340072 J. Biol. Chem. 2001 Mice|Animals|*DNA Repair|Pol beta protein, human|DNA Polymerase beta|PARP1 protein, human|*Poly (ADP-Ribose) Polymerase-1|Endonuclease, Apurinic|*Photoaffinity Labels|Poly(ADP-ribose) Polymerases|Flap Endonuclease 1|DNA|DNA Replication|Fibroblasts | |
11340081 J. Biol. Chem. 2001 WAS protein, human|*Wiskott-Aldrich Syndrome Protein|*Actins|*Phosphatidylinositol|*Polymerization|WASL protein, human|Wiskott-Aldrich Syndrome Protein, Neuronal|Wiskott-Aldrich Syndrome|NCK2 protein, human|Adaptor Proteins, Signal Transducing|Arp2-3 Complex|Oncogene Proteins|Actin-Related Protein 3|Actin-Related Protein 2|SH3 Domains|Filaments, Actin|Carrier Proteins|Nerve Tissue Proteins | |
11340163 Mol. Cell. Biol. 2001 PMC87003 Animals|*Anaphase Promoting Complex|*Cyclin A|*Anaphase|CDK2 protein, human|*Cyclin-Dependent Kinase 2|Cyclin B|Cell Cycle Proteins|Cyclin-Dependent Kinases|histone H1 kinase|Protein Kinases|CDH1 protein, human|*Cadherins|S Phase|Ubiquitin-Protein Ligases|Cell Cycle|CDC2 Protein Kinase|Mitosis|Phosphorylation | |
11340167 Mol. Cell. Biol. 2001 PMC87014 Humans|Mice|Animals|*Nuclear Respiratory Factor 1|peroxisome-proliferator-activated receptor-gamma coactivator-1|Transcription Factors|Nuclear Respiratory Factors|NF-E2-Related Factor 1|Trans-Activators|DNA-Binding Proteins|Transcriptional Activation|Promoter Regions, Genetic|Cell Nucleus|*Serum|Mitochondria|Up-Regulation | |
11340169 Mol. Cell. Biol. 2001 PMC87023 Mice|Animals|*Phospholipase C gamma|*Mast Cells|*Calcium|VAV1 protein, human|*Proto-Oncogene Proteins c-vav|Fc epsilon RI|Signal Transduction|Phosphorylation|Tyrosine Kinase|Cell Degranulation|Adaptor Proteins, Signal Transducing|Phosphoproteins|Cell Cycle Proteins|Carrier Proteins|Proto-Oncogene Proteins|Mitogen-Activated Protein Kinases|Protein-Serine-Threonine Kinases|Intracellular Signaling Peptides and Proteins | |
11340171 Mol. Cell. Biol. 2001 PMC87031 Mice|Animals|*C EBPalpha|*Leukopoiesis|DNA-Binding Proteins|Transcription Factors|Cell Differentiation|Promoter Regions, Genetic|Granulocyte|*Hematopoiesis|Cell Line|Myeloid Progenitor Cells|Downregulation|Binding Site|Protein Binding | |
11340297 Exp. Clin. Immunogenet. 2001 Humans|*Interleukin-2|IL15 protein, human|*Interleukin-15|*Phosphorylation|*Tyrosine|*T Cells|GAB2 protein, human|*Adaptor Proteins, Signal Transducing|PTPN11 protein, human|*Protein Tyrosine Phosphatase, Non-Receptor Type 11|STAT5A protein, human|*STAT5 Transcription Factor|*Tumor Suppressor Proteins|Signal Transduction|Phosphoproteins|SH2 Domain-Containing Protein Tyrosine Phosphatases|Mitogen-Activated Protein Kinases|src Homology Domains | |
11341778 Biochem. Biophys. Res. Commun. 2001 hydroxyphytanoyl-coenzyme A|phytanoyl-coenzyme A|*Phytanic Acid|*Peroxisomes|pristanal|pristanal dehydrogenase|pristanic acid|*Fatty Acids|*Aldehyde Oxidoreductases|*Aldehydes|Coenzyme A|Refsum Disease|Oxidation-Reduction|Microbodies|Hydroxylation|2-hydroxyphytanoyl-coenzyme A lyase|Carbon-Carbon Lyases|Catalysis | |
11341840 Biochemistry 2001 coactivator-associated arginine methyltransferase 1|*Protein-Arginine N-Methyltransferases|*Methylation|*Histones|N,N-dimethylarginine|dimethylarginine|Acetylation|Transcription Factors|Nuclear Proteins|omega-N-Methylarginine|*Posttranslational Modifications|Receptors, Nuclear | |
11341920 Biochim. Biophys. Acta 2001 Humans|*Complement Factor B|*Surface Plasmon Resonance|Complement C4b|Complement C4|Complement Inactivator Proteins|Binding Site|Protein Binding|Strengths, Ionic | |
11342111 Biochim. Biophys. Acta 2001 Humans|*DNA, Complementary|*Thiamin Pyrophosphokinase|Base Sequence|Cloning, Molecular|Amino Acid Sequence|Sequence Alignment|Blotting, Northern|mRNA|Thiamin|Sequence Analysis, DNA|Sequence Homology, Amino Acid|Escherichia coli | |
11342117 Biochim. Biophys. Acta 2001 Male|Female|Adult|Pregnancy|Humans|Mice|Animals|*Thiamin Pyrophosphokinase|*Cloning, Molecular|Thiamin|Amino Acid Sequence|Thiamine Pyrophosphate|Sequence Alignment|cDNA|Gene Library|mRNA|Saccharomyces cerevisiae | |
11342143 Biochim. Biophys. Acta 2001 Humans|Animals|Rats|*Amino Acids|*Amino Acid Transport System A|Amino Acid Sequence|Amino Acid Transport Systems|Biological Transport|*Liver|Carrier Proteins|2,2-dimethyl-beta-alanine|beta-Alanine|Cloning, Molecular|Cationic Amino Acid Transporters|DNA, Complementary|Xenopus laevis|Exons|Tissue Distribution|RNA, Messenger|Substrate Specificity|Sequence Homology, Amino Acid | |
11342438 Blood 2001 Humans|*Factor XIa|*Factor IX|*Blood Platelets|*Factor IXa|Blood Coagulation|*Molecular Conformation|Prekallikrein|Blood Coagulation Tests|Binding Sites|Dimerization|Kinetics|Protein Dimerization | |
11343657 Neuron 2001 *N-Methylaspartate|*Synapses|*Receptors, N-Methyl-D-Aspartate|Perforant Path|Excitatory Postsynaptic Potentials|Dentate Gyrus|Long-Term Potentiation|Synaptic Transmission|Neurons|Neuronal Plasticity|*Transcription, Genetic|Excitatory Amino Acid Antagonists|Nerve Tissue Proteins|*Signal Transduction|Cytoskeletal Proteins|mRNA | |
11344168 J. Biol. Chem. 2001 *Carrier Proteins|*Mitochondria|Saccharomyces cerevisiae Proteins|Mitochondrial Membrane Transport Proteins|Saccharomyces cerevisiae|Integral Membrane Proteins|Membrane Transport Proteins|Protein Transport|Intracellular Membranes|HSP70 Heat-Shock Proteins|Protein Precursors|Biological Transport|Amino Acid Sequence|Repressor Proteins|TIM23 protein, S cerevisiae|TIM44 protein, S cerevisiae | |
11345900 Vitam. Horm. 2001 Humans|*17 beta-Oestradiol|*Transcriptional Activation|*Estrogens|Estrogen Nuclear Receptor|estrogen receptor alpha, human|Estrogen Receptor alpha|Promoter Regions, Genetic|Sp1 Transcription Factor|DNA-Binding Proteins|Gene Expression|Transfection|Nuclear Proteins|Genes, fos|Gene Expression Regulation, Neoplastic|Binding Site|Response Elements|Tumor Cells, Cultured|Sp1 protein, human | |
11346801 Nature 2001 ADP-ribosylation factor 6|ADP-Ribosylation Factors|ADP-Ribosylation Factor 1|Guanosine Diphosphate|Guanosine Triphosphate|Carrier Proteins|Adaptor Proteins, Signal Transducing|*Signal Transduction|Amino Acid Sequence|Golgi Apparatus|Models, Molecular | |
11347887 Biol. Chem. 2001 Humans|cysteinyl-tRNA synthetase|*cDNA|Escherichia coli|*Amino Acyl-tRNA Synthetases|Amino Acid Sequence|Base Sequence|Cloning, Molecular|Exons|Cytoplasm|mRNA|Saccharomyces cerevisiae | |
11348591 Cell 2001 Humans|Animals|Tuberous Sclerosis 2|*Tuberous Sclerosis|*Drosophila|Tuberous Sclerosis Complex 2 Protein|*Cell Cycle|Tuberous Sclerosis Complex 1 Protein|Tumor Suppressor Proteins|Cell Division|*Cell Proliferation|Cell Cycle Proteins|Cyclin|Cyclin A|Genes, Tumor Suppressor|Repressor Proteins|CCNE1 protein, human|Cyclin E|Hamartoma|Cell Size | |
11348592 Cell 2001 Animals|Tuberous Sclerosis 2|*Tuberous Sclerosis|*Drosophila|*Insulin|*Organ Size|*Tuberous Sclerosis Complex 2 Protein|*Cell Cycle|Tuberous Sclerosis Complex 1 Protein|*Signal Transduction|Tumor Suppressor Proteins|Drosophila Proteins|*Cell Proliferation|Genes, Tumor Suppressor|Repressor Proteins|Cell Size|Mutation | |
11349134 J. Biol. Chem. 2001 Animals|Chlorocebus aethiops|*Epidermal Growth Factor|*Inositol Polyphosphate 5-Phosphatases|phosphatidylinositol 3,4,5-triphosphate|*COS Cells|*Phosphatidylinositol|EGFR protein, human|*Epidermal Growth Factor Receptor|*src Homology Domain|Phosphatidylinositol Phosphates|Phosphorylation|Signal Transduction|*Inositol Phosphates|Insulin|Tyrosine|Proto-Oncogene Proteins c-akt|Phosphoric Monoester Hydrolases|Shc Signaling Adaptor Proteins|Plasma Membranes | |
11350120 Genomics 2001 Humans|Mice|Animals|*Cloning, Molecular|*Promoter Regions, Genetic|cDNA|*Cell Differentiation|Keratinocytes|Base Sequence|Epidermis|Amino Acid Sequence|Intron|Skin|Blotting, Northern|Epidermal Cells|Genome|RNA, Messenger|Transcription Factor E2F1 | |
11350179 Mol. Genet. Metab. 2001 Cricetinae|Animals|Humans|*alpha-Mannosidase|CHO Cells|Cricetulus|alpha-Mannosidosis|*Lysosomes|mannose-6-phosphate|Mannosephosphates|Mannosidases|Lysosomal Storage Diseases|Kinetics|Fibroblasts|cDNA | |
11350191 Mol. Genet. Metab. 2001 Humans|*DNA Mutational Analysis|Methylmalonyl-CoA Mutase|Methylmalonic acidemia|Amino Acid Metabolism, Inborn Errors|Methylmalonic Acid|Homozygotes|Mutation|Phenotype | |
11350924 EMBO J. 2001 PMC125470 ATP dependent 26S protease|*Proteasome Endopeptidase Complex|*Peptides|*Antigens|Antigen Presentation|MHC Class I Molecules|Aminopeptidases|OVA-8|Ovalbumin|Epitopes|Leucine Aminopeptidase|Cysteine Endopeptidases|Amino Acids|Peptide Fragments|Protein Binding|Interferon-gamma|Protein Transport | |
11350927 EMBO J. 2001 PMC125460 Animals|*Drosophila|Drosophila Proteins|Drosophila melanogaster|Zymogens|Body Patterning|Serine Endopeptidases|Signal Transduction|Embryogenesis|Sulfotransferases|Gastrulation|*Cell Differentiation|Ligands | |
11350971 J. Biol. Chem. 2001 Humans|Female|*Tumor Suppressor Protein p53|*Ovarian Cancer|*Cell Line, Tumor|*Response Element|*Carcinoma, Ovarian Epithelial|Promoter Regions, Genetic|Binding Site|DNA-Binding Proteins|Base Sequence|Genes, p53|Protein Binding|Transfection|DNA | |
11350981 J. Biol. Chem. 2001 *Na(+)-H(+)-Exchangers|*Calcineurin|Binding Site|Amino Acid Sequence|Protein Binding|Calcium-Binding Proteins|Sodium|Hydrogen-Ion Concentration|Cell Line|Transfection|Cell Membrane | |
11353085 Nucleic Acids Res. 2001 PMC55463 Humans|Animals|Cyclic AMP Response Element-Binding Protein|*Gene Expression Regulation|Leucine Zippers|Promoter Regions, Genetic|Transcriptional Activation|Base Sequence|Regulatory Sequences, Nucleic Acid|CCAAT-Enhancer-Binding Proteins|Activating Transcription Factor 2|Transfection|Amino Acid Sequence|Cell Nucleus|*Mammals|*Liver | |
11353333 Curr. Opin. Lipidol. 2001 apolipoprotein C-I, human|*Apolipoprotein C-I|lipoprotein triglyceride|Triglycerides|ApoC III|Apolipoproteins C|Lipoproteins, VLDL|VLDL receptor|LDL Receptor|Hypertriglyceridemia|LDLR protein, human|Lipoproteins, LDL|Lipoprotein Lipase|Apolipoproteins E|Lipolysis|Hyperlipidemias | |
11353842 Proc. Natl. Acad. Sci. U.S.A. 2001 PMC33424 *Phosphatidylinositol 3-Kinase|GAB1 protein, human|GRB2 protein, human|GRB2 Adaptor Protein|Signal Transduction|Phosphorylation|Mitogen-Activated Protein Kinases|Phosphoproteins|SH3 Domain|Membrane Proteins|Fibroblast Growth Factor|Phospholipase C gamma|Receptor, Fibroblast Growth Factor, Type 1|Cell Differentiation|MAP Kinase Signaling System|Protein Binding | |
11356008 Cytokine 2001 Humans|STAT3 protein, human|*Signal Transducer and Activator of Transcription 3|*Interleukin-6|*Transcriptional Activation|*Proto-Oncogene Proteins c-fos|Proto-Oncogene Proteins c-jun|Transcription Factor AP-1|Promoter Regions, Genetic|Trans-Activators|Transcription, Genetic|Tetradecanoylphorbol Acetate|Response Element|Cyclic AMP Response Element-Binding Protein|Protein Binding|Signal Transduction|Transfection|Phosphorylation|ICAM1 protein, human | |
11356169 Biochem. Soc. Trans. 2001 *Carnitine O-Palmitoyltransferase|Malonyl CoA|*Isoforms|*Muscle|Amino Acid Sequence|*Liver|Carnitine|Kinetics|Pichia|*Musculoskeletal System|Structure-Activity Relationship | |
11356846 J. Biol. Chem. 2001 Animals|Humans|*Alkaline Ceramidase|*Hydrolysis|Ceramidases|Neutral Ceramidase|Ceramides|Amidohydrolases|Sphingosine|Amino Acid Sequence|Substrate Specificity|Sequence Alignment|Saccharomyces cerevisiae|Cloning, Molecular|Endoplasmic Reticulum|Sphingolipids|*Mammals|Golgi Apparatus|cDNA|Hydrogen-Ion Concentration | |
11356866 J. Neurosci. 2001 PMC6762685 Animals|Mice|*Myelin Sheath|*Myelin Basic Protein|Schwann Cells|Mice, Transgenic|Oligodendroglia|Transgene|Genes, Reporter|Axons|Promoter Regions, Genetic|Myelin Proteins|Regulatory Sequences, Nucleic Acid|Gene Expression|beta-Galactosidase|Nerves, Peripheral | |
11357136 Nature 2001 Mice|Animals|*Low Density Lipoprotein Receptor-Related Protein-6|CTNNB1 protein, human|beta Catenin|Wnt Proteins|Frizzled Receptors|Xenopus laevis|Xenopus Proteins|Signal Transduction|*Carrier Proteins|Zebrafish Proteins|Intercellular Signaling Peptides and Proteins|Protein Binding|Trans-Activators|Amino Acid Sequence|Proto-Oncogene Proteins|Embryonic Induction|Receptors, LDL|Dkk2 protein, Xenopus | |
11358837 Cancer Res. 2001 VHL protein, human|*Von Hippel-Lindau Tumor Suppressor Protein|HIF1A protein, human|*Hypoxia-Inducible Factor 1, alpha Subunit|Nuclear Proteins|Trans-Activators|Ligases|Ubiquitins|Amino Acid Sequence|Basic Helix-Loop-Helix Transcription Factors|Protein Binding|Hypoxia|Gene Expression Regulation | |
11358862 Genes Dev. 2001 PMC313798 Animals|*Cell Polarity|*Cell Signaling|Drosophila|Drosophila Proteins|Frizzled Receptors|Dishevelled Proteins|Phosphoproteins|Adaptor Proteins, Signal Transducing|Wnt1 Protein|Receptors, G-Protein-Coupled|Membrane Proteins|Cytoplasm|Phenotype|dsh protein, Drosophila | |
11358993 J. Leukoc. Biol. 2001 *Mast Cells|*Protein Kinase C-theta|Receptors, IgE|Phosphorylation|Genes, src|Mitogen-Activated Protein Kinases|Signal Transduction|Protein Kinase C-delta|src-Family Kinases|Mitogen-Activated Protein Kinase 1|Immunoglobulin E|Cell Line|Carrier Proteins | |
11359012 Science 2001 Endosomes|Golgi Complex|Receptor, Mannose 6 Phosphate|Intracellular Signaling Peptides and Proteins|Vesicular Transport Proteins|Pregnancy Proteins|DNA-Binding Proteins|rab GTP-Binding Proteins|Protein Transport|Binding Site|Protein Binding|Biological Transport|Amino Acid Sequence|Lysosomes|Cytosol | |
11359766 J. Biol. Chem. 2001 Mice|Animals|MDM2 protein, human|*Proto-Oncogene Proteins c-mdm2|*Phosphorylation|*Cyclin-Dependent Kinases|*Cyclin B1|TP53 protein, human|Tumor Suppressor Protein p53|CDK2 protein, human|Cyclin-Dependent Kinase 2|Cyclin|Cyclin A|CDC2 Protein Kinase|Nuclear Proteins|Tumor Suppressor Protein p14ARF|Proto-Oncogene Proteins|Genes, cdc|S Phase|Protein Binding | |
11360177 Oncogene 2001 *Signal Transduction|Phosphorylation|Proto-Oncogene Proteins c-ret|GDNF protein, human|Glial Cell Line-Derived Neurotrophic Factor|Glial Cell Line-Derived Neurotrophic Factor Receptors|GRB2 Adaptor Protein|Proto-Oncogene Proteins|Multiple Endocrine Neoplasia Type 2a|Phosphoproteins|Mitogen-Activated Protein Kinases|Phosphatidylinositol 3-Kinases|src Homology Domains|Protein Binding|Binding Site|Proto-Oncogene Proteins c-akt|Adaptor Proteins, Vesicular Transport|Shc Signaling Adaptor Proteins | |
11368773 Biochem. J. 2001 PMC1221857 Humans|*Phosphorylation|Phosphatidylinositol 3-Kinases|ZAP70 protein, human|*ZAP-70 Protein-Tyrosine Kinase|T Cell Receptor|Adaptor Proteins, Signal Transducing|Phospholipase C gamma1|Phosphoproteins|Lymphocyte Activation|Carrier Proteins|Signal Transduction|Membrane Proteins|Protein-Tyrosine Kinases|Jurkat Cells|Intracellular Signaling Peptides and Proteins|Tyrosine|Syk Kinase|LAT protein, Human herpesvirus 2 | |
11369260 Trends Cardiovasc. Med. 2001 *Very-Low-Density Lipoproteins|APOB protein, human|Apolipoprotein B-100|Apo B|Rough Endoplasmic Reticulum|*Cytoplasm|Triglycerides|microsomal triglyceride transfer protein|Carrier Proteins|Liver|ADP-Ribosylation Factor 1 | |
11369620 Blood 2001 Humans|*5'-Nucleotidase|*Haemolytic Anaemia|Anemia, Hemolytic, Congenital|Homozygote|Mutation|*Purine-Pyrimidine Metabolism, Inborn Errors|Erythrocyte|Exons | |
11369651 Blood 2001 Humans|STAT3 protein, human|*STAT3 Transcription Factor|*Proto-Oncogene Proteins c-kit|Signal Transduction Pathways|STAT1 protein, human|STAT1 Transcription Factor|Proto-Oncogene Proteins c-akt|Phosphatidylinositol 3-Kinases|Mitogen-Activated Protein Kinases|*Cytokines|Stem Cell Factor|Proto-Oncogene Proteins|Phosphoinositide-3 Kinase Inhibitors|Trans-Activators|*Leukemia|Phosphorylation|Chromones|Apoptosis | |
11369759 J. Biol. Chem. 2001 *CCAAT-Enhancer-Binding Protein-alpha|CDK2 protein, human|Cyclin-Dependent Kinase 2|*Phosphorylation|Cyclin-Dependent Kinases|Cyclins|CDC2-CDC28 Kinases|Cyclin-Dependent Kinase Inhibitor p21|Cell Cycle|Cyclin-Dependent Kinase Inhibitor p27|Genes, cdc|Cell Line|Microtubule-Associated Proteins|DNA | |
11369763 J. Biol. Chem. 2001 Chlorocebus aethiops|Animals|GPER1 protein, human|*Receptors, Estrogen|Endothelial Cells|NOS3 protein, human|*Endothelial Nitric Oxide Synthase|estrogen receptor alpha, human|ERalpha|*Receptors, G-Protein-Coupled|Nitric Oxide Synthase|COS-7 Cells|Signal Transduction|Enzyme Activation|Estradiol-17beta|Nitric Oxide|Plasma Membranes|Endothelium, Vascular|Phosphorylation|G Proteins | |
11371164 J. Mol. Biol. 2001 Animals|Humans|Rabbits|*Glucose-6-Phosphate Isomerase|*Protein Binding|Crystallography, Xray|Protein Conformation|Binding Site|*Catalysis|Substrate Specificity|Models, Molecular|Amino Acid Sequence|Active Site|Glucose-6-Phosphate|Crystallization|*Signal Transduction|*Haemolytic Anaemia|Cytokines | |
11371342 Cell 2001 Animals|Humans|pituitary tumor-transforming protein 1, human|*Securin|cohesins|Cell Cycle Proteins|Chromosomal Proteins, Non-Histone|Anaphases|*Stability, Chromosomal|Mitoses|Separase|Centromere|Saccharomyces cerevisiae Proteins|Nuclear Proteins|Phosphoproteins | |
11373284 J. Biol. Chem. 2001 *Superoxides|*Nitric Oxide|*Peroxynitrous Acid|*Oxidation-Reduction|Nitrates|Free Radicals|Xanthine Oxidase|Oxidants|Glutathione|Kinetics|Diffusion | |
11375391 J. Biol. Chem. 2001 *Calcium|*Group IV Phospholipases A2|Golgi Apparatus|*Phospholipases A2, Cytosolic|Cytosol|Endoplasmic Reticulum|Phospholipases A|*Calcium, Dietary|Calcimycin|Intracellular Membranes|Arachidonic Acid|Protein Transport|Catalytic Domain | |
11375483 Science 2001 Animals|Mice|*Signal Transduction|Heterotrimeric GTP-Binding Proteins|Phospholipase C beta|TYRP1 protein, human|*Membrane Glycoproteins|Plasma Membrane|GTP-Binding Protein alpha Subunits, Gq-G11|Type C Phospholipases|Phosphatidylinositol 4,5-Diphosphate|Phosphorylation|Protein Binding|Isoenzymes|Amino Acid Sequence|Cell Nucleus|Gene Expression Regulation|Hydrolysis | |
11375957 Gastroenterology 2001 *Carcinoma, Hepatocellular|*Liver Neoplasms|*Mutation|Loss of Heterozygosity|beta Catenin|Trans-Activators|*Carcinogenesis | |
11375980 J. Biol. Chem. 2001 Humans|*Glypicans|Heparan Sulfate Proteoglycan|Heparitin Sulfate|Slit homolog 2 protein|Nerve Tissue Proteins|*Carrier Proteins|heparin, O-desulfated|Heparin|Recombinant Proteins|Amino Acid Sequence|Protein Binding|Binding Sites|Ligands|Transfection | |
11375993 J. Biol. Chem. 2001 Humans|Female|Rats|Animals|MMP3 protein, human|*Matrix Metalloproteinase 3|*Matrix Metalloproteinase 7|*Osteopontin|Integrins|Amino Acid Sequence|Cell Movement|Protein Binding|Tumor Cell Lines|Wound Healing|Thrombin | |
11376695 Mutat. Res. 2001 Humans|Mice|Animals|*Recombinational DNA Repair|DNA Repair|DNA Damage|Rad51 Recombinase|BRCA2 protein, human|BRCA2 Protein|DNA-Binding Proteins|*Chromosome Stability|*Mammalian Chromosome|*Mammals|Chromosomal Breaks|*DNA|Cell Survival|Cell Nucleus|Phases, G2 | |
11377399 Biochem. Pharmacol. 2001 Male|Humans|*Lactate Dehydrogenases|*Catalytic Domain|lactate dehydrogenase 1|*L-Lactate Dehydrogenase|lactate dehydrogenase C4|Oxamic Acid|Gossypol|Pyruvate|Isoenzymes|Kinetics|NAD|Binding Sites | |
11378386 Curr. Biol. 2001 Humans|*PPAR gamma|*Up-Regulation|Caco-2 Cells|PTEN protein, human|*PTEN Phosphohydrolase|AKT1 protein, human|Protein Kinase B|Rosiglitazone|*Transcriptional Activation|Thiazolidinediones|Signal Transduction|Transcription Factors|*Anti-Inflammatory Agents|Phosphorylation|Thiazoles|Cell Migration|Cell Proliferation|Response Elements | |
11380445 Br. J. Haematol. 2001 Humans|Cricetinae|Chlorocebus aethiops|Animals|B-domain-deleted factor VIII|F8 protein, human|*Factor VIII|CHO Cells|Cricetulus|Hemophilia A|von Willebrand Factor|Transfection|Mutations, Missense|Mutagenesis, Site-Directed|*Hemostatics|Phenotype|Mutations|*Cross Reactions|COS Cells|Gene Expression|Peptide Fragments | |
11380459 Br. J. Haematol. 2001 *Spherocytosis, Hereditary|Anion Exchange Protein 1, Erythrocyte|Erythrocyte Membrane|Point Mutation|Alleles|Base Sequence|Erythrocyte|Mutation|Codon|Pedigree|Membrane Proteins|mRNA|Polymerase Chain Reaction|South Africa | |
11380615 Exp. Dermatol. 2001 *Proprotein Convertase|Furin|Serine Endopeptidases|Subtilisins|Proprotein Convertase 5|Proprotein Convertase 1|Protein Processing, Post-Translational|Enzyme Precursors|*Epidermal Cells|Gene Expression|Protein Precursors|Substrate Specificity|*Epidermis|Amino Acid Sequence | |
11381136 Proc. Natl. Acad. Sci. U.S.A. 2001 PMC34393 Humans|GART protein, human|*Phosphoribosylglycinamide Formyltransferase|*Escherichia coli|*Carbon-Nitrogen Ligases|Hydroxymethyl and Formyl Transferases|purine|Purines|Crystallography, X-Ray|Structure-Activity Relationship|Binding Sites | |
11381255 Nat. Genet. 2001 Humans|*Vitamin A|*Lecithins|Retinal Dystrophy, Early Onset Severe|*Eye Diseases, Hereditary|*Retinal Dystrophies|lecithin-retinol acyltransferase|*Acyltransferases|*Mutations|11-cis-Retinal|Retinoids | |
11382926 J. Cell. Physiol. 2001 *Receptor, DR4|TP53 protein, human|*Tumor Suppressor Protein p53|TNF-Related Apoptosis-Inducing Ligand|*DNA Damage|Apoptosis Regulatory Proteins|Apoptosis|TNFRSF10C protein, human|Receptors, Tumor Necrosis Factor, Member 10c|Antineoplastic Agents|Tumor Necrosis Factor-alpha|Transcriptional Activation|Transfection|Upregulation|Gene Expression Regulation, Neoplastic|Tumor Cells, Cultured|DNA|GPI-Linked Proteins | |
11384965 J. Biol. Chem. 2001 Humans|*CASP8 and FADD-Like Apoptosis Regulating Protein|CASP8 protein, human|*Caspase 8|FASLG protein, human|*Fas Ligand Protein|*Fas-Associated Death Domain Protein|*Transcriptional Activation|*Up-Regulation|*TNF-Related Apoptosis-Inducing Ligand|Caspases|fas Receptor|Receptors, TNF-Related Apoptosis-Inducing Ligand|*Viral Proteins|*Genes, fos|Jurkat Cells|Caspase 9|Apoptosis|Tumor Necrosis Factor-alpha | |
11385580 Nature 2001 Humans|Animals|Cricetinae|Pregnancy|Female|KISS1 protein, human|*Kisspeptins|Cricetulus|KISS1R protein, human|Receptors, Kisspeptin-1|*Ligands|GPRC5C protein, human|*Receptors, G-Protein-Coupled|*Peptides|Amino Acid Sequence|Genes, Tumor Suppressor|Transfections|CHO Cells|Cell Movement|Chemotaxis | |
11387206 EMBO J. 2001 PMC125255 NTN1 protein, human|*Netrin-1|DCC Receptor|Netrin-1 Receptors|Nerve Growth Factors|Receptors, Cell Surface|Caspases|Neurons|Tumor Suppressor Proteins|Apoptosis|Cell Movement|Cells, Cultured|Cell Line|Transfection | |
11387210 EMBO J. 2001 PMC125481 Humans|*Vascular Endothelial Growth Factor A|*Phospholipase C gamma|*Phosphorylation|*Endothelial Cells|Receptors, Vascular Endothelial Growth Factor|KDR protein, human|*Tyrosine Kinase, KDR|Receptors, Growth Factor|Receptor Protein-Tyrosine Kinases|Vascular Endothelial Growth Factors|Signal Transduction|*DNA Replication|Mitogen-Activated Protein Kinases|Endothelium, Vascular|Tyrosine|DNA | |
11387316 J. Biol. Chem. 2001 Humans|ABCB11 protein, human|*ATP Binding Cassette Transporter, Subfamily B, Member 11|farnesoid X-activated receptor|*Receptors, Cytoplasmic and Nuclear|*Promoter Regions, Genetic|Transcription Factors|DNA-Binding Proteins|Bile Acids|Transcription, Genetic|Hepatocyte|Response Elements|Binding Site|ATP-Binding Cassette Transporters|Transfection|RNA, Messenger | |
11389039 Blood 2001 Humans|Cattle|Animals|Swine|CAP18 lipopolysaccharide-binding protein|antimicrobial peptide LL-37|*Myeloblastin|*Antimicrobial Cationic Peptides|Cathelicidins|Anti-Infective Agents|*Anti-Bacterial Agents|Neutrophils|Peroxidase|Elastase|Exocytosis | |
11389151 J. Biol. Chem. 2001 *Guanine Nucleotide Dissociation Inhibitors|geranylgeranyltransferase type-I|Alkyl and Aryl Transferases|Protein Prenylation|rab GTP-Binding Proteins|Sequences, Amino Acid|Adaptor Proteins, Signal Transducing|Golgi Apparatus|Cell Membrane|Protein Transport|Endoplasmic Reticulum|Mutation|*Membrane|Guanine Nucleotides | |
11389444 Nat. Cell Biol. 2001 *Transforming Growth Factor beta|SMAD2 protein, human|*Smad2 Protein|SMAD3 protein, human|Smad3 Protein|SKIL protein, human|*Intracellular Signaling Peptides and Proteins|*Proto-Oncogene Proteins|Ubiquitin|Ubiquitin Ligase E3|Signal Transduction|Receptors, Transforming Growth Factor beta|Trans-Activators|*Cytoplasm|Protein-Serine-Threonine Kinases|Proteasome|Activin Receptors, Type I|Transcription, Genetic | |
11389445 Nat. Cell Biol. 2001 Animals|*Drosophila|Drosophila melanogaster|*Proto-Oncogene Proteins c-akt|*Signal Transduction|EIF4E|Binding Proteins|Drosophila Proteins|Phosphoproteins|Protein Biosynthesis|Intracellular Signaling Peptides and Proteins|*Protein Synthesis Inhibitors|Phosphorylation|Amino Acid Sequence|*Cell Cycle|RNA Caps|Messenger RNA | |
11389842 Mol. Cell 2001 activin receptor type II-B|Activin Receptors, Type II|SMAD2 protein, human|Smad2 Protein|Transforming Growth Factor beta|ACVR2B protein, human|Nodal Protein|Activin Receptors, Type I|Signal Transduction|Neoplasm Proteins|GPI-Linked Proteins|Transcription Factors|Bone Morphogenetic Proteins|Xenopus Proteins|Epidermal Growth Factor|Homeodomain Proteins|Protein Binding|Membrane Proteins | |
11389890 FEBS Lett. 2001 Mice|Animals|lipoic acid synthase|*DNA, Complementary|*Thioctic Acid|*Sulfurtransferases|*Mitochondria|Escherichia coli|Amino Acid Sequence|Cloning, Molecular|Sequence Homology, Amino Acid|Bacterial Proteins|Arabidopsis | |
11390354 Genes Dev. 2001 PMC312712 Animals|*Drosophila|Drosophila melanogaster|*Protein Inhibitors of Activated STAT|Heterochromatin|Position Effect Variegation|*Chromosome Structure|Drosophila Proteins|Centromeres|Gene Silencing|Chromosomal Proteins, Non-Histone|Telomere|Repressor Proteins|Mutations|Interphase|Suppression, Genetic | |
11390358 Genes Dev. 2001 PMC312704 Humans|Animals|*Insulin|*Signal Transduction|Tuberous Sclerosis Complex 2 Protein|Tuberous Sclerosis Complex 1 Protein|Proto-Oncogene Proteins c-akt|Tumor Suppressor Proteins|TOR Serine-Threonine Kinases|Ribosomal Protein S6 Kinases|Sclerosis, Tuberous|Proto-Oncogene Proteins|Repressor Proteins|Phosphorylation|Genes, Tumor Suppressor|Drosophila|Mutations|Cell Size | |
11390368 J. Biol. Chem. 2001 Humans|*Caspase 1|APAF1 protein, human|*Apoptotic Protease-Activating Factor 1|CASP9 protein, human|Procaspase-9|Caspases|Caspase-Dependent Apoptosis|Amino Acid Sequence|Protein Structure, Tertiary|Protein Binding|Sequence Homology, Amino Acid|Enzyme Activation|Transfections | |
11390408 J. Biol. Chem. 2001 Humans|*Phosphorylation|CHEK2 protein, human|*CDS1 Kinase|Cell Cycle Proteins|*Ionizing Radiation|Protein Kinases|Nuclear Proteins|DNA Damage|Ataxia Telangiectasia Mutated Proteins|DNA-Binding Proteins|Tumor Suppressor Proteins|Tumor Suppressor Protein p53|Threonine|Mutation|Amino Acid Sequence|Ataxia-Telangiectasia | |
11390453 J. Immunol. 2001 IL10 protein, human|*Interleukin-10|interleukin-22|*T-Lymphocytes|*Factor 10|interleukin-22 receptor|Receptors, Interleukin|Interleukins|Cytokine Receptor|*Protein Binding|*Signal Transduction|Cytokines|Amino Acid Sequence|Recombinant Proteins|Cloning, Molecular|Carrier Proteins | |
11390454 J. Immunol. 2001 Humans|Cricetinae|Animals|interleukin-22|interleukin-22 receptor|Receptors, Interleukin|Interleukins|Cytokine Receptor|Protein Binding|Amino Acid Sequence|Signal Transduction|Up-Regulation|Suppressor of Cytokine Signaling Proteins|Cloning, Molecular | |
11390642 Mol. Cell. Biol. 2001 PMC87074 Humans|*Phosphorylation|Protein Kinase|Cell Cycle Proteins|Ataxia Telangiectasia Mutated Proteins|DNA Damage|Checkpoint Kinase 1|Tumor Suppressor Proteins|DNA-Binding Proteins|Tumor Suppressor Protein p53|Serine|ATR protein, human | |
11390647 Mol. Cell. Biol. 2001 PMC87079 Mice|Animals|*Protein Tyrosine Kinase|*MAP Kinase Signaling System|*Signal Transduction|Receptor Tyrosine Kinase RET|Multiple Endocrine Neoplasia Type 2|Phosphorylation|*Oncogenes|Proto-Oncogene Proteins|Glial Cell Line-Derived Neurotrophic Factor Receptors|GRB2 Adaptor Protein|Shc Signaling Adaptor Proteins|Adaptor Proteins, Vesicular Transport|Mitogen-Activated Protein Kinases|Phosphatidylinositol 3-Kinases|Proto-Oncogene Proteins c-akt|3T3 Cells|Drosophila Proteins|Binding Site | |
11390650 Mol. Cell. Biol. 2001 PMC87082 Humans|*Phospholipase C gamma1|*src Homology Domains|SLP-76 signal Transducing adaptor proteins|*Phosphoproteins|*Adaptor Proteins, Signal Transducing|Nuclear Proteins|Receptors, Antigen, T-Cell|DNA-Binding Proteins|Signal Transduction|Phosphorylation|Carrier Proteins|Membrane Proteins|Jurkat Cells|NFATC Transcription Factors|Protein-Tyrosine Kinases|Lymphocyte Activation|*Protein Domains|Binding Sites | |
11390669 Mol. Cell. Biol. 2001 PMC87101 Cricetinae|Animals|Humans|*Integral Membrane Proteins|Peroxins|Peroxisomes|*Protein Transport|Intracellular Membranes|Carrier Proteins|Protein Structure, Tertiary|Cytosol|Molecular Chaperones|CHO Cells|Binding Sites | |
11391482 Am. J. Hum. Genet. 2001 PMC1226048 Animals|*Exostoses, Multiple Hereditary|exostosin-1|*Point Mutation|exostosin-2|*N-Acetylglucosaminyltransferases|*Mutations|*Heparitin Sulfate|Mutations, Missense|Cell Line|Frameshift Mutation|Phenotypes | |
11394999 Neuron 2001 Humans|Mice|Animals|*Myelin Sheath|Transcription Factor, EGR2|Schwann Cells|Transcription Factors|DNA-Binding Proteins|Myelin Proteins|*Peripheral Nervous System Diseases|SOXE Transcription Factors|Gene Expression Regulation|*Mutations|Sciatic Nerve|*Gene Expression|Phenotype|EGR2 protein, human|Egr2 protein, mouse | |
11395409 Annu. Rev. Biochem. 2001 PMC4781088 Animals|*Phospholipase C gamma|PLCB3 protein, human|*Phospholipase C beta|phospholipase C epsilon|*Phosphoinositide Phospholipase C|Phosphatidylinositol|G Proteins|Phospholipase C delta|Enzyme Activation|Isozymes|Signal Transduction|Protein Binding|glycerophosphoinositol glycerophosphodiesterase|*Phosphoric Diester Hydrolases|Binding Sites|Receptors, Cell Surface|Inositol Phosphates | |
11395415 Annu. Rev. Biochem. 2001 *Transcription Factors|Transcription Factor TFIID|TATA-Binding Protein Associated Factors|DNA-Binding Proteins|Chromatin|Histone Acetyltransferases|Saccharomyces cerevisiae Proteins|Transcription Factors, TFII|Trans-Activators|Transcription, Genetic|Nuclear Proteins|Transcriptional Activation|Histones|Promoter Regions, Genetic|Gene Expression Regulation | |
11395417 Annu. Rev. Biochem. 2001 *Phosphorylation|Phosphatidylinositol 3-Kinases|Phosphoinositide-3 Kinase Inhibitors|Phosphoinositides|Wortmannin|Chromones|Proto-Oncogene Proteins c-akt|PTEN Phosphohydrolase|Enzyme Inhibitors|Morpholines|Androstadienes|Inositol | |
11395502 J. Biol. Chem. 2001 Animals|Humans|ORC1 protein, human|*Origin Recognition Complex|Saccharomyces cerevisiae|Cell Cycle Proteins|*Chromosome Structures|Cell Cycle|Protein Binding|Cell Nucleus|HeLa Cells|ORC5 protein, S cerevisiae|Saccharomyces cerevisiae Proteins | |
11395778 Nature 2001 SHH protein, human|*Hedgehog Proteins|Patched Receptors|*Signal Transduction|PTCH protein, human|Patched-1 Receptor|HHIP protein, human|Carrier Proteins|Membrane Glycoproteins|Trans-Activators|Membrane Proteins|Body Patterning|Receptors, Cell Surface|*Diffusion|Gene Expression Regulation, Developmental | |
11396616 Mol. Membr. Biol. 2001 Humans|Rats|Animals|Organic Anion Transporters, Sodium-Dependent|Sodium-Coupled Vitamin C Transporters|*Ascorbic Acid|Co-Transporters|Dehydroascorbic Acid|Biological Transport|Sodium|Biological Transport, Active|Glucose Transport Facilitators|Diffusion|Kinetics|Isoforms|Tissue Distribution|Cell Membrane|Glucose | |
11397817 J. Biol. Chem. 2001 Humans|*Bilirubin|*Ultrafiltration|*Human Serum Albumin|Serum Albumin|Protein Binding|Kinetics|*Physical Phenomena | |
11401429 Genomics 2001 Humans|Animals|Mice|*Saccharomyces cerevisiae|*Magnesium|MRS2 protein, human|*Mitochondrial Proteins|*Cation Transport Proteins|*Mitochondria|Saccharomyces cerevisiae Proteins|*Yeast, Dried|Genetic Complementation Test|Sequence Homology, Amino Acid|Amino Acid Sequence|Nuclear Proteins|Introns|Exons|Cloning, Molecular | |
11401442 Genomics 2001 Humans|*Apolipoprotein A-II|*Hereditary Amyloidosis|Amyloidosis|Base Sequence|Amyloid|Kidney Diseases|Mutation|Amino Acid Sequence|fibrinogen Aalpha|Fibrinogen|Stop Codon|Pedigree|Apolipoprotein AI|Heterozygote | |
11402059 J. Cell Biol. 2001 PMC2192020 Peroxisomes|peroxisomal membrane protein 34|*Integral Membrane Proteins|Peroxin|Intracellular Membranes|Cytoplasm|Protein Transport|Amino Acid Sequence|Biological Transport|Luminescent Proteins|Green Fluorescent Proteins|Membrane Transport Proteins|Protein Binding|Sequence Homology, Amino Acid | |
11402316 Oncogene 2001 Animals|*DNA Breaks, Double-Stranded|*Epistasis, Genetic|RAD52 protein, human|*Rad52 DNA Repair and Recombination Protein|DNA Repair|DNA-Activated Protein Kinase|DNA Damage|Recombination, Genetic|DNA-Binding Proteins|DNA|Ku Autoantigen|Kinetics|Saccharomyces cerevisiae|*Vertebrate|RAD52 protein, S cerevisiae|Saccharomyces cerevisiae Proteins|RAD54 protein, S cerevisiae|DNA Helicases | |
11404376 J. Leukoc. Biol. 2001 Mice|Animals|*Interferon|*Antiviral Agents|Oligonucleotide Array Sequence Analysis|Cytokines|Gene Expression Profiling|Gene Expression Regulation|Signal Transduction | |
11404413 J. Neurosci. 2001 PMC6762758 Animals|*Axon Guidance|roundabout protein|Nerve Tissue Proteins|Receptors, Immunologic|Axons|Olfactory Bulb|Growth Cones|Intercellular Signaling Peptides and Proteins|Ganglia, Dorsal Root|Cell Movement|*Proteolysis|Vertebrates|Brain | |
11404481 Proc. Natl. Acad. Sci. U.S.A. 2001 PMC34666 Mice|Animals|*Platelet-Derived Growth Factor|STAT3 protein, human|*STAT3 Transcription Factor|*Cell Transformation, Neoplastic|src-Family Kinases|Oncogene Protein pp60(v-src)|Signal Transduction|Trans-Activators|Proto-Oncogene Proteins c-myc|STAT1 Transcription Factor|Gene, c-myc|Phosphorylation|3T3 Cells|*Cell Proliferation | |
11406411 Trends Biochem. Sci. 2001 *RNA Editing|*Deamination|Adenosine Deaminase|Inosine|RNA|Cytidine Deaminase|tRNA|Amino Acid Sequence|Substrate Specificity|RNA Precursors|Cytidine | |
11406611 Hum. Mol. Genet. 2001 Humans|tiglyl-coenzyme A|3-methylcrotonyl CoA carboxylase 1 deficiency|*Carbon-Carbon Ligases|*Mutations|*Acyl Coenzyme A|Exons|Allele|Urea Cycle Disorders, Inborn|Base Sequence|cDNA|Amino Acid Sequence|Missense Mutation|Sequence Analysis, DNA|Phenotypes|Biotin|Cloning, Molecular | |
11408476 J. Biol. Chem. 2001 Humans|*Recruitment Domain, Caspase|CASP9 protein, human|Caspase 9|APAF1 protein, human|Apoptotic Protease-Activating Factor 1|Caspases|*Apoptosis|Amino Acid Sequence|Carrier Proteins|Staurosporine|*Cancer|Protein Structure, Tertiary|Enzyme Activation|Adaptor Proteins, Signal Transducing | |
11408587 Mol. Biol. Cell 2001 PMC37343 Humans|*Phosphorylation|*MAP Kinase Signaling System|MAPK1 protein, human|*Mitogen-Activated Protein Kinase 1|*Mitogen-Activated Protein Kinases|Golgi Apparatus|Mitosis|U 0126|Butadienes|Golgi Matrix Proteins|*Antigens, Differentiation|MAP Kinase Kinase 1|Membrane Proteins|*Receptors, Cytokine|Nitriles|HeLa Cells | |
11409944 Chem. Res. Toxicol. 2001 Rats|Humans|Animals|*Aflatoxin B1|*Aldo-Keto Reductases|AKR1B1 protein, human|Aldehyde Reductase|AKR1A1 protein, human|Liver|Glutathione Transferase|Amino Acid Sequence|Chromatography, High Pressure Liquid|Kinetics|Anticarcinogenic Agents|Cytosol | |
11410592 J. Biol. Chem. 2001 Humans|*Genes, bcl-1|HeLa Cells|*Estrogens|CCND1 protein, human|Cyclin D1|estrogen receptor alpha, human|ERalpha|Activation, Transcriptional|Promoter Regions, Genetic|Estradiol|Up-Regulation|Response Elements|Transcription Factors|Binding Sites|Gene Expression Regulation, Neoplastic|Cell Cycle|Protein Kinase A|Signal Transduction | |
11413485 Nat. Rev. Mol. Cell Biol. 2001 *Calcium|*Calcium Signaling|Inositol 1,4,5-Trisphosphate Receptors|Ryanodine Receptor Calcium Release Channel|Endoplasmic Reticulum|Cell Death|Apoptosis|Necrosis | |
11414355 Immunol. Rev. 2001 Complement C1r|Complement C1s|Complement C1|Protein Conformation|Complement C1q|Protein Binding|Binding Sites|Models, Molecular | |
11414686 Arch. Biochem. Biophys. 2001 *Dermatan Sulfate|Iduronic Acid|Chondroitin|BGN protein, human|Biglycan|Carbohydrate Epimerases|Sulfotransferases|Fibroblasts | |
11414710 Biochem. Biophys. Res. Commun. 2001 Humans|Mice|Animals|*Stearoyl-CoA Desaturase|*Transcriptional Activation|*Binding Protein|*Promoter Regions, Genetic|*Cholesterol|*Regulatory Sequences, Nucleic Acid|*Sterols|*Polyunsaturated Fatty Acids|Sterol Regulatory Element Binding Protein 1a|Base Sequence|CCAAT-Enhancer-Binding Proteins|Triglycerides|palmitoleic acid|Fatty Acids, Monounsaturated|mRNA|Cholesterol Esters|Cloning, Molecular | |
11415433 Biochem. J. 2001 PMC1221925 Humans|Animals|Mice|*Coenzyme A|nudix hydrolases|HeLa Cells|*Pyrophosphatases|Peroxisomes|CoA, Acyl|red fluorescent protein|Luminescent Proteins|Amino Acid Sequence|Sequence Alignment|Cloning, Molecular|Substrate Specificity|Saccharomyces cerevisiae|Sequence Homology, Amino Acid|Liver|Kinetics|Kidney | |
11416019 Endocrinology 2001 Humans|dehydroepiandrosterone sulfotransferase|*Hydroxycholesterols|*Sulfotransferases|alcohol sulfotransferase|*Cholesterol|Amino Acid Sequence|Cloning, Molecular|Substrate Specificity|Kinetics|Isoforms|Sequence Homology, Amino Acid|Dehydroepiandrosterone|Oxysterols | |
11416152 Mol. Cell. Biol. 2001 PMC87164 Humans|*Retinoblastoma|PCTAIRE-1 protein kinase|CDK2 protein, human|Cyclin-Dependent Kinase 2|CDK6 protein, human|Cyclin-Dependent Kinase 6|Cyclin|CCNE1 protein, human|Cyclin E|CDC2-CDC28 Kinases|Retinoblastoma Protein|Cyclin-Dependent Kinase 4|Phosphorylation|E2F Transcription Factors|Transcription Factors|Cyclin D|Proto-Oncogene Proteins|Cell Cycle | |
11417227 Pflugers Arch. 2001 Humans|Mice|Animals|SLC3A2 protein, human|*Fusion Regulatory Protein 1, Heavy Chain|Transporters, Amino Acid|Amino Acid Sequence|Antigen 4F2|Carrier Proteins|Cystine|Amino Acids|L-Glutamate|DNA, Complementary|Amino Acid Transport System y+|Oocytes|Biological Transport|Xenopus laevis|mRNA|Cloning, Molecular|Surface Antigen|Plasma Membrane | |
11418238 Gene 2001 Humans|Chlorocebus aethiops|Mice|Animals|Base Sequence|FGFR1 protein, human|Receptor, Fibroblast Growth Factor, Type 1|Receptor, Fibroblast Growth Factor, Type 5|Introns|Amino Acid Sequence|DNA, Complementary|Cloning, Molecular|mRNA|Blotting, Northern|FGFR2c|Sequence Alignment|Fibroblast Growth Factors|Signal Transduction|Exons|Recombinant Proteins|Alternative Splicing|Phosphorylation | |
11418623 J. Immunol. 2001 *Receptor, IL-21|IL2RG protein, human|*Interleukin Receptor Common gamma Subunit|JAK1 protein, human|Janus Kinase 1|IL21R protein, human|*Interleukin-21 Receptor alpha Subunit|STAT1 protein, human|STAT1 Transcription Factor|STAT3 protein, human|STAT3 Transcription Factor|JAK3 protein, human|Janus Kinase 3|Signal Transduction|interleukin-21|Interleukins|Receptors, Interleukin|STAT5 Transcription Factor | |
11418668 J. Immunol. 2001 Mice|Animals|Humans|thymic stromal lymphopoietin|*Cytokines|interleukin-7 receptor, alpha chain|Receptors, Interleukin-7|Receptors, Cytokine|*Myeloid Cells|STAT5A protein, human|STAT5 Transcription Factor|Interleukin-7|STAT3 protein, human|STAT3 Transcription Factor|B7-1 Antigen|Dendritic Cells|Signal Transduction|Cell Differentiation|Cells, Cultured|CD40 Antigens|Phosphorylation | |
11419947 J. Mol. Biol. 2001 Animals|*Lactose Synthase|N-acetyllactosaminide alpha-1,3-galactosyltransferase|*Galactosyltransferases|Uridine Diphosphate Galactose|*Catalysis|Protein Conformation|Binding Site|Crystallography, X-Ray|Kinetics|Lactalbumin|Milk|Uridine Diphosphate Glucose|Hydrogen Bonding|Substrate Specificity|Models, Molecular|Crystallization|N-Acetyllactosamine Synthase|Amino Acid Sequence | |
11420179 Biochim. Biophys. Acta 2001 Male|Humans|PEMT protein, human|*Phosphatidylethanolamine N-Methyltransferase|Methyltransferases|cDNA|Methylation|phosphatidylethanolamine|Phosphatidylethanolamines|Liver|Cloning, Molecular|Exons|5' UTR|RNA, Messenger|Promoter Regions, Genetic|Phosphatidyl Choline | |
11421344 Glycoconj. J. 2001 PMC7087979 *Sialic Acid|Sialic Acids|Neuraminic Acids|Cell Membranes | |
11421366 RNA 2001 PMC1370139 *RNA Precursors|*Introns|*RNA Splicing|CPSF Protein|RNA Processing, Post-Transcriptional|Poly A|mRNA Cleavage and Polyadenylation Factors|RNA-Binding Proteins|RNA, Messenger|Viral Nonstructural Proteins|Protein Binding|Amino Acid Sequence | |
11423117 FEBS Lett. 2001 Kv Channel-Interacting Proteins|Shal Potassium Channels|Calcium-Binding Proteins|Patch-Clamp Techniques|Protein Subunits|Amino Acid Sequence|Oocytes | |
11423440 Biophys. J. 2001 PMC1301537 Humans|*Capsid|*HIV-1|*Capsid Proteins|Virus Assembly|HIV Infections|TYRP1 protein, human|*Membrane Glycoproteins|Electron Microscopy|*HIV Seropositivity|Hydrogen-Ion Concentration | |
11423904 Cell Death Differ. 2001 Humans|*Intermediate Filaments|*Vimentin|*Caspases|*Apoptosis|CASP3 protein, human|Caspase 3|Caspase 6|Staurosporine|HeLa Cells|Cell Death|Jurkat Cells|Protein Binding | |
11425186 Glycoconj. J. 2001 beta-D-galactoside alpha 2-6-sialyltransferase|Sialyltransferases|neolactotetraosylceramide alpha-2,3-sialyltransferase|N-acetyllactosaminide alpha-2,3-sialyltransferase|Sialic Acid|lactosamine|Amino Sugars|Oligosaccharides|Glycoproteins|beta-galactoside|Galactosides|Glycolipids | |
11425315 Biochemistry 2001 Animals|*Hexose Transporter|SLC2A1 protein, human|*Glucose Transporter Type 1|Sequences, Amino Acid|3-O-Methylglucose|Biological Transport|Mutagenesis, Site-Directed|Xenopus laevis|Methylglucosides|Deoxyglucose|Active Transport|Oocytes|Kinetics|Cell Membrane|Adenosine Triphosphate | |
11425794 Glycobiology 2001 dolichol monophosphate|Dolichol Phosphates|*Endoplasmic Reticulum|dolichol-D-glucosylmonophosphate|Polyisoprenyl Phosphate Monosaccharides|Dolichol|Glycosylation|Saccharomyces cerevisiae|Oligosaccharides|*Lipogenesis | |
11425858 J. Biol. Chem. 2001 *Casein Kinase Iepsilon|*Wnt Signaling Pathway|CTNNB1 protein, human|beta Catenin|Wnt Proteins|Trans-Activators|Phosphoproteins|Axin Protein|Dishevelled Proteins|Adaptor Proteins, Signal Transducing|Zebrafish Proteins|Casein Kinases|Xenopus Proteins|Protein Kinases|Proto-Oncogene Proteins|Repressor Proteins|Phosphorylation|Protein Binding | |
11425868 J. Cell Biol. 2001 PMC2150726 *Phosphatidylinositol 3-Kinase|Phosphatidylinositol 3-Kinases|*Receptors, IgG|*Phagocytosis|*Signal Transduction|Phagosomes|Phosphoinositides|*Cell Membrane|Phosphatidylinositol Phosphates|Proto-Oncogene Proteins c-akt|Macrophages|Phosphoric Monoester Hydrolases|GAB1 protein, human|Adaptor Proteins, Signal Transducing|Phosphoproteins | |
11427533 J. Biol. Chem. 2001 Humans|HDAC1 protein, human|*Histone Deacetylase 1|Homeodomain Proteins|Repressor Proteins|Histone Deacetylase|Transcription, Genetic|Trans-Activators|Transforming Growth Factor beta|Genes, Homeobox|Holoprosencephaly|Protein Binding|Mutation|Transfection|TGIF2 protein, human | |
11427698 Physiol. Rev. 2001 Animals|Mice|*Spectrin|*Ankyrins|*Inventions|Erythrocyte Membrane|Membrane Proteins|Cytoskeletal Proteins|Erythrocytes|adducin|Calmodulin-Binding Proteins|Actin|Protein Binding|*Actin Cytoskeleton|Ion Channel | |
11427719 Proc. Natl. Acad. Sci. U.S.A. 2001 PMC35427 Humans|CASP8 protein, human|*Caspase 8|*Cytomegalovirus|*Apoptosis|Caspases|CFLAR protein, human|CASP8 and FADD-Like Apoptosis Regulating Protein|Caspase 9|fas Receptor|Caspase Inhibitors|Cell Death|Enzyme Activation|Signal Transduction | |
11427893 Nat. Struct. Biol. 2001 Humans|Animals|*Substrate Specificity|deoxyribonucleoside kinases|Phosphotransferases (Alcohol Group Acceptor)|Phosphorylation|Kinetics|Binding Site|Amino Acid Sequence|Drosophila melanogaster|Models, Molecular|Nucleoside Analogs|purine|Purines|Thymine Nucleotides|Hydrogen Bonding | |
11429401 J. Biol. Chem. 2001 Animals|Humans|*Neuroglobin|*Oxygen|*Hemoglobin|Kinetics|Recombinant Proteins|Protein Binding|Myoglobin|Nerve Tissue Proteins|Cytoglobin|Ligands|Models, Molecular|Cloning, Molecular|Histidine|*Biophysical Phenomena | |
11429702 Oncogene 2001 Humans|Mice|Animals|FGFR3 protein, human|*Receptor, Fibroblast Growth Factor, Type 3|*Multiple Myeloma|*Cell Line, Tumor|NIH 3T3 Cells|Chromosomal Translocation|Phosphorylation|STAT3 protein, human|STAT3 Transcription Factor|Signal Transduction|STAT1 protein, human|STAT1 Transcription Factor|Mitogen-Activated Protein Kinases|Cell Division | |
11430795 Neuron 2001 *Schwann Cells|periaxin|dystrophin-related protein 2|Myelin Sheath|Muscle Proteins|Dystroglycan|Dystrophin|Axons|Membrane Glycoproteins|Cytoskeleton | |
11430802 Neuron 2001 Mice|Animals|*Utrophin|*Schwann Cells|periaxin|dystrophin-related protein 2|Myelin|Muscle Proteins|Dystroglycan|Dystrophin|Cell Membrane|Membrane Glycoproteins|Axons | |
11430804 Neuron 2001 Animals|*Drosophila|*Phosphorylation|Casein Kinase Iepsilon|Drosophila Proteins|Period Circadian Proteins|CLOCK Proteins|Circadian Rhythm|Clock, Circadian|Nuclear Proteins|Cell Nucleus|timeless protein, Drosophila | |
11431473 J. Biol. Chem. 2001 rho GTPase-activating protein|GTPase-Activating Proteins|RHOA protein, human|rhoA GTP-Binding Protein|*Signal Transduction|*Amino Acid Motifs|cdc42 GTP-Binding Protein|Amino Acid Sequence|rac1 GTP-Binding Protein|src Homology Domain|TRIP10 protein, human|Microtubule-Associated Proteins|cDNA|Cytoskeleton|Protein Structure, Tertiary|Blotting, Northern|Transfections|Minor Histocompatibility Antigens | |
11431483 J. Biol. Chem. 2001 Humans|Rats|Mice|Animals|trimethyl-lysine hydroxylase|epsilon-N-trimethyllysine hydroxylase|*Mixed Function Oxygenases|Amino Acid Sequence|L-Carnitine|cDNA|alpha Ketoglutarate|trimethyllysine|Lysine|Amino Acids|*Biochemical Phenomena|Mitochondria|Saccharomyces cerevisiae | |
11431687 Nat. Genet. 2001 Hemochromatosis, type 4|*Hemochromatosis|metal transporting protein 1|*Cation Transport Proteins|Iron Overload|*Mutation|Ferritins|Genes, Dominant|Pedigree|Mutation, Missense | |
11432792 J. Biochem. 2001 Humans|tropomyosin-related kinase-B, human|*Receptor, trkB|*Phosphorylation|*Two-Hybrid System Techniques|*Signal Transduction|*Membrane Glycoproteins|PTPN11 protein, human|Protein Tyrosine Phosphatase, Non-Receptor Type 11|GRB2 protein, human|GRB2 Adaptor Protein|SIRPA protein, human|Receptors, Immunologic|Antigens, Differentiation|SH2 Domain-Containing Protein Tyrosine Phosphatases|Protein Tyrosine Phosphatase, Non-Receptor Type 6|Phosphoproteins|Mitogen-Activated Protein Kinases|Neural Cell Adhesion Molecules | |
11432829 EMBO J. 2001 PMC125513 PTPN12 protein, human|*Protein Tyrosine Phosphatase, Non-Receptor Type 12|*Lymphocyte Activation|*Protein Tyrosine Phosphatase|PXN protein, human|Paxillin|Protein Binding|Signal Transduction|src Homology Domains|Cytoskeletal Proteins|Shc Signaling Adaptor Proteins|Phosphorylation|Binding Sites|Src Homology 2 Domain-Containing, Transforming Protein 1|Adaptor Proteins, Vesicular Transport | |
11433015 Nucleic Acids Res. 2001 PMC55769 *RNA Polymerase II|transcription factor S-II|Transcriptional Elongation Factors|Transcription, Genetic|Transcription Factors|Templates, Genetic|Transcription Factor TFIIH|*Cell Nucleus|RNA Polymerases|Base Sequence|Promoter Regions, Genetic | |
11433026 Nucleic Acids Res. 2001 PMC55773 Humans|8-hydroxyguanine|*Adenine|isoguanine|*Guanine|adenine glycosylase|DNA Glycosylase|DNA Repair|Base Pair Mismatch|DNA Replication|Proliferating Cell Nuclear Antigen|DNA|Protein Binding|Escherichia coli|Cell Nucleus|Amino Acid Sequence|Cell Cycle | |
11433298 Nat. Cell Biol. 2001 *PtdIns|*Endosomes|phosphatidylinositol 3-phosphate|Phosphatidylinositol Phosphates|Sorting Nexin|Vesicular Transport Proteins|Protein Transport|Carrier Proteins|Protein Binding|Amino Acid Sequence|Protein Structure, Tertiary|Transport Vesicles|Lysosome|Cell Line|Transfection | |
11433302 Nat. Cell Biol. 2001 Humans|CTNNB1 protein, human|beta Catenin|*Signal Transduction|Wnt Proteins|Low Density Lipoprotein Receptor-Related Protein-6|LDLR protein, human|Low Density Lipoprotein Receptor|Receptor, Frizzled|Intercellular Signaling Peptides and Proteins|Low Density Lipoprotein Receptor-Related Protein-5|Protein Binding|Zebrafish Proteins|Proto-Oncogene Proteins|Xenopus Proteins|Trans-Activators|LRP6 protein, human | |
11435302 Blood 2001 Mice|Animals|*Stem Cell Factor|*Chemotaxis|Proto-Oncogene Proteins c-kit|*Cell Proliferation|Mast Cells|Phosphorylation|src-Family Kinases|Signal Transduction|Enzyme Activation|Hematopoietic Stem Cells|Bone Marrow Cells|Cells, Cultured|Cell Differentiation|Hematopoietic Stem Cell Transplantation | |
11435466 J. Clin. Invest. 2001 PMC209337 Humans|Mice|Animals|*Cell Death|Caspases|TNF Receptors|Signal Transduction|Receptors, Tumor Necrosis Factor, Type I|Ceramides|Apoptosis|Sphingomyelin Phosphodiesterase|Sphingomyelins|Mitogen-Activated Protein Kinases|Tumor Necrosis Factor-alpha|Adaptor Proteins, Signal Transducing|p38 Mitogen-Activated Protein Kinases|Intracellular Signaling Peptides and Proteins|Fibroblasts|Carrier Proteins | |
11440719 Cell 2001 Animals|*Drosophila|*Circadian Clocks|*Glycogen Synthase Kinase 3|Period Circadian Proteins|Drosophila Proteins|Circadian Rhythm|Drosophila melanogaster|Phosphorylation|Nuclear Proteins|Phenotype|Cell Nucleus|Casein Kinase II|Mutation|shaggy protein, Drosophila|timeless protein, Drosophila | |
11440997 J. Biol. Chem. 2001 Humans|Animals|Mice|Pol beta protein, human|*DNA Polymerase beta|*B-DNA|*Base Excision Repair|PARP1 protein, human|*Poly (ADP-Ribose) Polymerase-1|Endonuclease, Apurinic|*DNA Replication|Uracil-DNA Glycosylase|Poly(ADP-ribose) Polymerases|Flap Endonuclease 1|DNA|*Recombination, Genetic|Adenosine Diphosphate Ribose | |
11441019 J. Biol. Chem. 2001 Humans|*B-DNA|Base Pair Mismatch|MutS Homolog 2 Protein|DNA-Binding Proteins|Mismatch Repair Endonuclease PMS2|DNA Repair Enzymes|DNA Repair|DNA|MutL Protein Homolog 1|Nuclear Proteins|Protein Binding|Adenosine Triphosphatases|Carrier Proteins|Heteroduplex DNA|Adaptor Proteins, Signal Transducing|Proto-Oncogene Proteins|biotin-streptavidin complex|Bacterial Proteins | |
11441146 Science 2001 *NAD|ARNTL Transcription Factors|CLOCK Proteins|Period Circadian Proteins|DNA-Binding Proteins|Trans-Activators|Nuclear Proteins|Nerve Tissue Proteins|*Redox|Circadian Rhythm|Biological Clocks|Cell Cycle Proteins|Gene Expression|Protein Binding|Dimerization|DNA | |
11441147 Science 2001 Mice|Animals|Suprachiasmatic Nucleus|Period Circadian Proteins|ARNTL Transcription Factors|CLOCK Proteins|Cryptochromes|Circadian Rhythm|Nuclear Proteins|Photoreceptor Cells, Invertebrate|Cell Cycle Proteins|Trans-Activators|Eye Proteins|Drosophila Proteins|Biological Clocks|*Prosencephalon|Gene Expression Regulation|Light-Dark Cycle|Gene Expression|mRNA | |
11443076 J. Bacteriol. 2001 PMC95336 *Aspartate Aminotransferase|Amino Acid Sequence|Methionine|Malaria, Falciparum|Plasmodium falciparum|Amino Acids|canaline|Aminobutyrates|Aspartate|Crithidia fasciculata|Alanine|Tyrosine|Trypanosoma brucei brucei|Kinetics|Regeneration | |
11443118 J. Biol. Chem. 2001 *Receptors, Erythropoietin|*src Homology Domains|*Signal Transduction|CRKL protein|*Adaptor Proteins, Signal Transducing|EPO protein, human|Erythropoietin|*Nuclear Proteins|JAK2 protein, human|Janus Kinase 2|Phosphorylation|PTPN11 protein, human|Protein Tyrosine Phosphatase, Non-Receptor Type 11|Protein Binding|Tyrosine|Protein Processing, Post-Translational | |
11445554 Glycobiology 2001 Humans|*Acetylgalactosamine|*Cloning, Molecular|chondroitin 4-sulfotransferase|*Sulfotransferases|HNK-1 sulfotransferase|CHST11 protein, human|*Sulfates|cDNA|Amino Acid Sequence|Base Sequence|*Glycans|Chromosome Mapping|Dermatan Sulfate|Chondroitin|*Sulfur Oxides|Oligosaccharides|Sequence Homology, Amino Acid|Expressed Sequence Tag | |
11447115 EMBO J. 2001 PMC125258 Cricetinae|Animals|*Junctional Adhesion Molecule|*Cell Polarity|*ASIP Protein|Cricetulus|JTB protein, human|PKC-3 protein|Protein Kinase C|Tight Junctions|Cell Adhesion Molecules|*Neoplasm Proteins|Cells, Epithelial|Intercellular Junctions|Caenorhabditis elegans|Caenorhabditis elegans Proteins|Carrier Proteins|Zonula Occludens-1 Protein|Helminth Proteins|Phosphoproteins | |
11447121 EMBO J. 2001 PMC125548 Humans|*Phosphorylation|*Serine|Transcription Factors|DNA-Binding Proteins|Heat Shock Transcription Factors|Heat-Shock Response|Transcription, Genetic|Heat-Shock Proteins|Transcriptional Activation|Amino Acid Sequence|Cell Nucleus|Transfection|HeLa Cells|Hot Temperature | |
11447212 J. Biol. Chem. 2001 Humans|HeLa Cells|*Protein Tyrosine Phosphatase|*Farnesylation, Protein|Immediate-Early Proteins|Rab geranylgeranyltransferase|Alkyl and Aryl Transferases|Neoplasm Proteins|Membrane Proteins|Cell Cycle Proteins|Saccharomyces cerevisiae|Amino Acid Sequence|Sequence Homology, Amino Acid | |
11447223 J. Biol. Chem. 2001 Humans|Mice|Animals|ANGPT1 protein, human|*Angiopoietin-1|ANGPT2 protein, human|*Angiopoietin-2|Endothelial Cells|Receptor, TIE 2|*Extracellular Matrix|Angiopoietins|Neovascularization, Pathologic|Endothelium, Vascular|Immunocytochemistry|Membrane Glycoproteins|*Peptides|Phosphorylation | |
11447225 J. Biol. Chem. 2001 Humans|TP53 protein, human|*Tumor Suppressor Protein p53|*Phosphorylation|*Reactive Oxygen Species|*Serine|Hydrogen Peroxide|polo-like kinase 1|*Protein-Serine-Threonine Kinases|PLK3 protein, human|Cell Cycle Proteins|Cyclin-Dependent Kinase Inhibitor p21|Cell Cycle|Apoptosis|Oxidative Stress|Transfection|Cell Line | |
11447289 Proc. Natl. Acad. Sci. U.S.A. 2001 PMC37478 Mice|Animals|GAB1 protein, human|FRS2 protein, human|*Receptor-Mediated Signal Transduction|*Membrane Proteins|Phosphoproteins|Mitogen-Activated Protein Kinases|src Homology Domains|GRB2 Adaptor Protein|Phosphorylation|Receptor, Fibroblast Growth Factor, Type 1|Cell Proliferation | |
11447294 Proc. Natl. Acad. Sci. U.S.A. 2001 PMC55384 Animals|*Golgi Apparatus|*Mitosis|polo-like kinase 1|*Protein-Serine-Threonine Kinases|*Cell Cycle Proteins|CDC2 Protein Kinase|GOLPH3 protein, human|Membrane Proteins|Phosphorylation|Golgi Matrix Proteins|*Proto-Oncogene Proteins|MAP2K1 protein, human|Mitogen-Activated Protein Kinase Kinase 1 | |
11448122 Cytokine 2001 Humans|leptin receptor, human|*Receptors, Leptin|*Leptin|STAT5A protein, human|STAT5 Transcription Factor|*Signal Transduction|STAT5B protein, human|STAT3 protein, human|STAT3 Transcription Factor|DNA-Binding Proteins|Trans-Activators|Phosphorylation|Western Blotting|Carrier Proteins|Tumor Suppressor Proteins|*Cell Line|Receptors, Cell Surface|*Liver | |
11448771 Curr. Biol. 2001 Animals|*Low Density Lipoprotein Receptor-Related Protein-6|Wnt Proteins|Receptor, Frizzled|*Ligands|beta Catenin|Signal Transduction|Xenopus Proteins|Zebrafish Proteins|Intercellular Signaling Peptides and Proteins|Protein Binding|Xenopus laevis|Trans-Activators|Proto-Oncogene Proteins|Receptors, LDL|Embryo, Nonmammalian | |
11448779 Curr. Biol. 2001 Humans|*Methylation|*Histones|*Arginine|coactivator-associated arginine methyltransferase 1|Protein Arginine Methyltransferase|*Posttranslational Modifications|*Receptors, Nuclear|Lysine|Acetylation|Transcription Factors|Activation, Transcriptional|Nuclear Receptor Coactivators|PRMT1 protein, human|Repressor Proteins | |
11448940 Hum. Mol. Genet. 2001 Humans|Diastrophic dysplasia|*Sulfate Transporters|Atelosteogenesis type 2|Multiple Epiphyseal Dysplasia|*Dwarfism|Achondrogenesis|*Phenotype|*Mutations|Carrier Proteins|Anion Transport Proteins|Genotype|Biological Transport|*Musculoskeletal Abnormalities|Proteoglycans|*Ion Transport|Sulfates | |
11448999 J. Cell Biol. 2001 PMC2196856 Mice|Animals|NIH 3T3 Cells|VAV3 protein, human|Proto-Oncogene Proteins c-vav|p190RhoGEF protein, human|VAV1 protein, human|RHOA protein, human|rhoA GTP-Binding Protein|Signal Transduction|cdc42 GTP-Binding Protein|rac GTP-Binding Proteins|rac1 GTP-Binding Protein|Oncogene Proteins|Protein Binding|Phosphorylation|Enzyme Activation|Epidermal Growth Factor|3T3 Cells|Transfection | |
11449000 J. Cell Biol. 2001 PMC2196853 Mice|Animals|ANK2 protein, human|*Ankyrins|*Lens, Crystalline|*Cataracts|connexin 50|Connexins|Gap Junctions|NRCAM protein, human|*Cell Adhesion Molecules|Axons|Eye Proteins|Disease Models, Animal | |
11449366 Eur. J. Immunol. 2001 *Tyrosine|*Immunoreceptor Tyrosine-Based Activation Motif|*Receptors, Antigen, B-Cell|B cell linker protein|*Adaptor Proteins, Signal Transducing|CD79B protein, human|*CD79 Antigens|src Homology Domain|Phosphoproteins|Signal Transduction|Phosphorylation|Carrier Proteins|Protein-Tyrosine Kinases|B-Lymphocytes|Intracellular Signaling Peptides and Proteins|Phospholipase C gamma2|Amino Acid Sequence|Antigens, CD | |
11451485 Virus Res. 2001 *Active Transport, Cell Nucleus|leptomycin B|exportin 1 protein|Karyopherins|*Orthomyxoviridae|Ribonucleoprotein|Receptors, Cytoplasmic and Nuclear|*Fatty Acids, Unsaturated|Cell Nucleus|Viral Proteins|Influenza A virus|Viral Matrix Proteins|Cytoplasm|RNA, Viral|Influenza|Cell Line | |
11451488 Virus Res. 2001 Humans|*Viral Proteins|*Influenza Viruses|Neuraminidase|Hemagglutinin Glycoproteins, Influenza Virus|Virus Assembly|*Cell Membrane|Viral Matrix Proteins|Influenza A virus|*Glycoproteins|Protein Transport|Membrane Microdomains|Cell Line|Vaccinia virus|Cell Polarity | |
11451954 J. Biol. Chem. 2001 Sentrin 1|Small Ubiquitin-Related Modifier Proteins|Ubiquitins|Ubiquitin-Conjugating Enzymes|Amino Acid Sequence|Binding Sites|Protein Binding|Sequence Homology, Amino Acid | |
11452016 Nucleic Acids Res. 2001 PMC55815 Cricetinae|Animals|*Receptors, Estrogen|*Estrogens|*Response Elements|ERbeta|ERalpha|Oestradiol|Transcriptional Activation|Protein Binding|Transfection|Genes, Reporter|DNA|CHO Cells | |
11452083 Science 2001 Humans|Animals|*Dicer Enzyme|*RNA Interference|*RNA, Small Temporal|Drosophila melanogaster|RNA, Helminth|RNA, Precursor|Caenorhabditis elegans|RNA, Double-Stranded|Messenger RNA|Conserved Sequence|Gene Expression Regulation, Developmental | |
11453642 Biochem. Biophys. Res. Commun. 2001 Animals|Cricetinae|Humans|*Peroxisomes|ABCD3 protein, human|*ATP-Binding Cassette Transporters|Membrane Proteins|Green Fluorescent Proteins|Intracellular Membranes|Amino Acid Sequence|CHO Cells | |
11453658 Biochem. Biophys. Res. Commun. 2001 Animals|Humans|Mice|*Cell Adhesion|*Cell Adhesion Molecules|Neurons|Membrane Proteins|Brain|In Situ Hybridization|Axons|Cerebral Cortex|*Biophysical Phenomena|Cerebellum|Cloning, Molecular|DSCAML1 protein, mouse|Dscam protein, mouse | |
11454738 EMBO Rep. 2001 PMC1083944 *Cell Nucleus|*Cytoplasm|Proteasome|Nuclear Proteins|HIF1A protein, human|*Hypoxia-Inducible Factor 1, alpha Subunit|*Oxygen|Ubiquitins|Von Hippel-Lindau Tumor Suppressor Protein|Ligases|Hypoxia|Cell Hypoxia|Protein Binding|Cysteine Endopeptidases|Signal Transduction | |
11454741 EMBO Rep. 2001 PMC1083948 Animals|Humans|Drosophila melanogaster|*Clathrin-Coated Vesicles|Synaptic Vesicle|Clathrin|Endocytosis|Calcium-Binding Proteins|Adaptor Protein Complex alpha Subunits|Adaptor Protein Complex 2|Adaptor Proteins, Vesicular Transport|Nerve Tissue Proteins|Synaptotagmin I|Exocytosis|Synaptic Membranes|Membrane Glycoproteins|Vesicular Transport Proteins|Drosophila Proteins|Cell Membrane|AP-2 protein, Drosophila | |
11454856 J. Biol. Chem. 2001 *DNA Breaks, Double-Stranded|ATM protein, human|*ATM Protein|Cell Cycle Proteins|*Cell Nucleus|Tumor Suppressor Proteins|H2AX protein, human|Histones|Phosphorylation|DNA-Binding Proteins|DNA Damage|DNA | |
11455963 RNA 2001 PMC1370153 Humans|*Ribonuclease P|*RNase|*Ribonuclease, Pancreatic|RNA, Catalytic|*Cell Nucleus|RNA|Amino Acid Sequence|Cloning, Molecular|Protein Subunits|HeLa Cells | |
11457664 J. Steroid Biochem. Mol. Biol. 2001 Male|Pregnancy|Animals|Female|Humans|Rabbits|*Hydroxysteroids|alcohol sulfotransferase|Sulfotransferases|Amino Acid Sequence|Isoforms|Cloning, Molecular|Substrate Specificity|Exon|Androgens|Alternate Splicing|Androsterone|Androstenediol|Kinetics|RNA, Messenger|Testosterone|Sequence Homology, Amino Acid|Pregnenolone|Placenta | |
11457814 J. Appl. Physiol. 2001 Humans|Infant, Newborn|calponin|Calcium-Binding Proteins|Myosin|Tropomyosin|Actin|Muscle, Smooth|Caldesmon|Muscle Proteins|Muscle Contraction|*Actin Cytoskeleton|*Sarcomeres|Phosphorylation | |
11457843 J. Biol. Chem. 2001 Humans|Cricetinae|Pregnancy|Female|Animals|Rats|KISS1 protein, human|*Kisspeptins|*Ligands|CHO Cells|Cricetulus|KISS1R protein, human|*Receptors, Kisspeptin-1|Receptors, G-Protein-Coupled|Amino Acid Sequence|Peptides|Pituitary Gland|Phosphorylation|Genes, Tumor Suppressor | |
11459787 Endocrinology 2001 Cricetinae|Pregnancy|Female|Animals|Humans|*Follistatin|*Follistatin-Related Proteins|Cricetulus|Activin|Inhibins|Glycoprotein|Protein Binding|Amino Acid Sequence|mRNA|CHO Cells|Ovary|Transfections | |
11459929 Proc. Natl. Acad. Sci. U.S.A. 2001 PMC55357 Animals|Humans|GPR15 protein, human|*G-Protein-Coupled Receptors|Biogenic Amine Receptors|*Mammals|Biogenic Amines|tryptamine|Tryptamines|Octopamine|Neurotransmitters|Tyramine|phenethylamine|Phenethylamines|Amino Acid Sequence|Vertebrates|Sequence Homology, Amino Acid|Phylogeny|Systems, Nervous|PCR | |
11459987 Proc. Natl. Acad. Sci. U.S.A. 2001 PMC37455 Animals|Humans|HeLa Cells|*Recombinational DNA Repair|XRCC2 protein, human|*DNA-Binding Proteins|X-ray repair cross complementing protein 3|RAD51C protein, human|RAD51 Protein|DNA Repair|Protein Binding|DNA|Baculovirus | |
11460167 Nature 2001 CHUK protein, human|*IkappaB Kinase|*Ubiquitin|Tifab protein, human|TRAF6|UBE2N protein, human|Ubiquitin-Conjugating Enzymes|Transductions, Signal|Phosphorylation|MAP Kinase Kinase Kinases|Ubiquitination|Polyubiquitin|Adaptor Proteins, Signal Transducing|NF-kappa B|Enzyme Activation|Interleukin 1|Protein Binding | |
11461910 J. Biol. Chem. 2001 Animals|*Ubiquitin|Caenorhabditis elegans|Caenorhabditis elegans Proteins|FBXW7 protein, human|*F-Box-WD Repeat-Containing Protein 7|Membrane Proteins|Helminth Proteins|Receptors, Notch|Cell Cycle Proteins|Proteasome|*Mammals|Signal Transduction|Amino Acid Sequence|E3 Ubiquitin Ligase|Cell Nucleus|Lin-12 protein, C elegans|SEL-10 protein, C elegans | |
11461920 J. Biol. Chem. 2001 Rats|Animals|*Dynactin Complex|SPTBN2 protein, human|*Spectrin|Dynein|Actin|Microtubule-Associated Proteins|Cytoskeleton|Microtubule|Protein Binding|Microfilament Proteins|Actin Cytoskeleton|Golgi Apparatus|Cytoplasm|Amino Acid Sequence|Binding Sites|Protein Transport|Protein Isoforms|Models, Molecular | |
11462236 Hum. Mutat. 2001 Humans|*Carboxypeptidase H|Diabetes Mellitus, Type 2|Exons|Amino Acid Sequence|Introns|Mutations|Carboxypeptidases|Single Nucleotide Polymorphisms|Carboxypeptidase B|Pedigree|Missense Mutation|Proinsulin | |
11463333 Biochem. J. 2001 PMC1221992 Nuclear Factor-Kappab|Tifab protein, human|TRAF6|Nuclear Proteins|Intracellular Signaling Peptides and Proteins|DNA-Binding Proteins|Tumor Necrosis Factor alpha-Induced Protein 3|Zinc Finger|Signal Transduction|Gene Expression Regulation|Tumor Necrosis Factor Receptor|Tumor Necrosis Factor-alpha|Cysteine Endopeptidases | |
11463336 Biochem. J. 2001 PMC1221995 Humans|Animals|Dogs|Rats|FN1 protein, human|*Fibronectins|*Whey|*Extracellular Matrix Proteins|Kallmann Syndrome|*Cell Adhesion|*Mutation|Nerve Tissue Proteins|*Models, Molecular|Neural Cell Adhesion Molecule|Extracellular Matrix|Cell Adhesion Molecules|Amino Acid Sequence|Cell Lines|Mutations, Missense|*Protein Domains|Substitutions, Amino Acid | |
11463377 Mol. Cell 2001 Humans|Mice|Animals|STAT3 protein, human|*STAT3 Transcription Factor|FASLG protein, human|Fas Ligand|Activation, Transcriptional|Proto-Oncogene Proteins c-jun|Trans-Activators|Transcription, Genetic|Transcription Factor AP-1|Response Elements|Promoter Regions, Genetic|fas Receptor|Up-Regulation|Proto-Oncogene Proteins c-fos|Protein Binding|Apoptosis|Signal Transduction|Downregulation | |
11463379 Mol. Cell 2001 Humans|*Nucleosomes|POU2F1 protein, human|*Octamer Transcription Factor-1|Transcription Factors|*Promoter Regions, Genetic|DNA-Binding Proteins|snRNA|Binding Sites|RNA Polymerase II|Host Cell Factor C1|Activation, Transcription|Transcription, Genetic|RNA Polymerase III|Octamer Transcription Factor-2|Amino Acid Sequence|DNA | |
11463392 Mol. Cell 2001 *Tumor Suppressor Protein p53|Apoptosis Regulatory Proteins|BCL2 protein, human|Proto-Oncogene Proteins c-bcl-2|Apoptosis|Caspases|APAF1 protein, human|Apoptotic Protease-Activating Factor 1|Proto-Oncogene Proteins|Mitochondria|Cytochrome c|Transcriptional Activation|Intracellular Signaling Peptides and Proteins | |
11463813 Mol. Cell. Biol. 2001 PMC87253 *NF-kappa B|CASP8 protein, human|Caspase-8|CASP8 and FADD-Like Apoptosis Regulating Protein|Apoptosis|RELA protein, human|*Transcription Factor RelA|Caspases|Tumor Necrosis Factor-alpha|Signal Transduction|Caspase 3|Upregulation|TRAF2|Downregulation|Cell Death|FASLG protein, human|Fas Ligand|Gene Expression Regulation | |
11463840 Mol. Cell. Biol. 2001 PMC87280 Humans|*Chromatin|*Caspase 6|*Matrix Attachment Region Binding Proteins|*PDZ Domains|*Dimerization|DNA-Binding Proteins|*Genes, Homeobox|Nuclear Matrix|*Apoptosis|DNA|Cell Nucleus|Binding Sites|Jurkat Cells|Protein Binding|SATB1 protein, human | |
11463847 Mol. Cell. Biol. 2001 PMC87287 Male|Animals|*Synaptonemal Complex|cohesins|*Synapsis|*Chromosomal Proteins, Non-Histone|*Cell Cycle Proteins|Chromatids|Meiosis|Chromosome Segregation|Nuclear Proteins|Phosphoproteins|DNA-Binding Proteins|*Germ Cells|Recombination, Genetic|DNA | |
11465543 Mutat. Res. 2001 Humans|*Thromboxane-A Synthase|Polymorphism, Genetic|Base Sequence|*Cytochrome P-450 Enzyme System|Mutations|Mutations, Missense|DNA|Amino Acid Sequence|Myocardial Infarction|Thromboxanes | |
11466320 J. Biol. Chem. 2001 Animals|Chlorocebus aethiops|*Ephrin-B1|*Phosphorylation|EPHB2 protein, human|*Receptor, EphB2|Receptor Protein-Tyrosine Kinases|Signal Transduction|Neurons|Membrane Proteins|*Nerve Tissue|Cell Membrane|Axons|Protein Binding|Tyrosine|Ligands|COS Cells|Retina|Cell Movement | |
11466363 J. Immunol. 2001 Humans|interleukin-1 epsilon|interleukin-1 delta|*NF-kappa B|Endothelial Cells|*Receptors, Interleukin-1|IL1B protein, human|*Interleukin-1beta|Interleukin 1 Receptor Antagonist Protein|IL1R2 protein, human|Receptors, Interleukin-1 Type II|RELA protein, human|Transcription Factor RelA|interleukin 18 protein, human|IL-18|Signal Transduction|Ligands|mRNA|Keratinocytes | |
11466412 J. Neurosci. 2001 PMC6762651 Rats|Animals|NGF protein, human|*Nerve Growth Factor|*Signal Transduction|*Endosomes|GAB2 protein, human|Adaptor Proteins, Signal Transducing|PC12 Cells|CRKL protein|Receptor, trkA|rap1 GTP-Binding Proteins|Mitogen-Activated Protein Kinases|Neurites|Nuclear Proteins|MAP Kinase Signaling System|Guanine Nucleotide Exchange Factor|Neurons|Epidermal Growth Factor | |
11466627 Oncogene 2001 Humans|Animals|*Chickens|Phylogeny|BRCA1 protein, human|*BRCA1 Protein|Genes, BRCA1|Amino Acid Sequence|Conserved Sequence|Sequence Homology, Amino Acid|Mutation, Missense|Mammal | |
11467836 Biochem. Biophys. Res. Commun. 2001 *Prealbumin|apolipoprotein A-IV|*Amyloidosis|*Apolipoproteins A|Amyloid|Myocardium|Amino Acid Sequence|Amyloidogenic Proteins|Immunohistochemistry | |
11470266 FEBS Lett. 2001 Swine|Animals|dolichyl-diphosphooligosaccharide - protein glycotransferase|*Asparagine|*Hexosyltransferases|*Membrane Proteins|3-hydroxynorvaline|*Threonine|Transferases|*Amino Acids|Peptides|Serine|Amino Acid Sequence|Glycosylation|Molecular Conformation|Cysteine|Kinetics|Liver | |
11470436 Structure 2001 mitochondrial processing peptidase|*Signal Sequences|*Metalloendopeptidase|Amino Acid Sequence|Substrate Specificity|Mitochondria|Models, Molecular|Protein Processing, Post-Translational|Arginine | |
11470797 J. Biol. Chem. 2001 Humans|*Acetylgalactosamine|*Cloning, Molecular|N-acetylgalactosamine-4-sulfotransferase|*Sulfotransferases|CHST11 protein, human|HNK-1 sulfotransferase|Iduronic Acid|cDNA|Amino Acid Sequence|Dermatan Sulfate|Base Sequence|Sequence Alignment|Chromosome Mapping|Sequence Homology, Amino Acid|Open Reading Frame|Transfection|Substrate Specificity|Exon | |
11470803 J. Biol. Chem. 2001 *Auxilins|*Clathrin|*Clathrin-Coated Vesicles|HSC70 Heat-Shock Proteins|Protein Binding|HSP70 Heat-Shock Proteins|Adaptor Proteins, Vesicular Transport|Heavy Chain, Clathrin|Amino Acid Sequence|*Synapses|*Intracellular Membranes | |
11470804 J. Biol. Chem. 2001 Humans|Rats|Chlorocebus aethiops|Animals|Mice|butyryl-CoA synthetase|*Coenzyme A Ligases|Amino Acid Sequence|cDNA|*RNA|Base Sequence|COS Cells|Acids, Fatty|Cloning, Molecular|Sequence Homology, Amino Acid|Mitochondria|mRNA|Substrate Specificity|Transfection|Liver|Tissue Distribution | |
11470823 J. Cell Biol. 2001 PMC2150770 Rats|Animals|DOK1 protein, human|*Phosphoproteins|*RNA-Binding Proteins|*DNA-Binding Proteins|Signal Transduction|Adaptor Proteins, Signal Transducing|Phosphorylation|GTPase-Activating Proteins|Oncogene Proteins|ras GAP|Proto-Oncogene Proteins c-ret|Protein Binding|Mitogen-Activated Protein Kinases|Tyrosine Kinase|Binding Sites|Cell Differentiation | |
11470829 J. Cell Biol. 2001 PMC2150779 Ranvier's Nodes|NRCAM protein, human|Cell Adhesion Molecules|*Sodium Channel|Axons|*Immunoglobulin-like Domain|Cell Adhesion Molecules, Neuronal|Nerve Growth Factors|FN1 protein, human|Fibronectin|Schwann Cells|Ankyrins|Neuroglia|Cell Adhesion|Nerve, Sciatic|Protein Binding | |
11470830 J. Cell Biol. 2001 PMC2150755 *Dystroglycans|Dystrophin|gephyrin|Utrophin|Membrane Glycoproteins|Muscular Dystrophies|Laminin|Agrin|Carrier Proteins|*Brain|Binding Sites|Neurons|Cytoskeleton|Neuroglia|Glycosylation|Extracellular Matrix Proteins | |
11470916 Proc. Natl. Acad. Sci. U.S.A. 2001 PMC55382 Rats|Animals|*Glucose|Transcription Factor|*Carbohydrate Metabolism|DNA-Binding Proteins|*Liver|Basic Helix-Loop-Helix Leucine Zipper Transcription Factors|Pyruvate Kinase, L-Type|Transcription, Genetic|Hepatocytes|Promoter Regions, Genetic|Response Element|Gene Expression Regulation|Transfection|Glycolysis|Cloning, Molecular | |
11473128 J. Biol. Chem. 2001 Humans|Mice|Animals|*Globin|*Neuroglobin|Ligands|Protein Binding|Kinetics|Nerve Tissue Proteins|Histidine|Heme|Recombinant Proteins|Carbon Monoxide|*Respiratory Transport|Protein Conformation|Oxygen|Iron|Oxidation-Reduction|*Biochemical Phenomena|Hydrogen-Ion Concentration|Disulfides | |
11473323 Nature 2001 *Replication Protein A|Okazaki fragments|*DNA|Saccharomyces cerevisiae|DNA Helicases|Saccharomyces cerevisiae Proteins|Flap Endonucleases|Adenosine Triphosphatases|*Endonucleases|DNA Replication|RNA primers|RNA|DNA Primers|Single-Stranded DNA-Binding Protein|RepB' protein, E coli|*Escherichia coli Proteins|*Chromosome Structures|Protein Binding | |
11476890 Biochim. Biophys. Acta 2001 Animals|Mice|*Focal Adhesion Protein-Tyrosine Kinases|PTK2 protein, human|*Focal Adhesion Kinase 1|Integrins|Paxillin|Signal Transduction|Cell Motility|Focal Adhesions|Mitogen-Activated Protein Kinases|Cell Adhesion|Cytoskeletal Proteins|Mitogen-Activated Protein Kinase 3|Phosphorylation|Extracellular Matrix|Cell Survival | |
11476961 Biochim. Biophys. Acta 2001 Humans|*Syndrome|Familial HDL deficiency|*Hypoalphalipoproteinemias|Tangier Disease|ABCA1 protein, human|ATP Binding Cassette Transporter 1|*Genetic Testing|*Mutations|Hypolipoproteinemias|Exons|Pedigree|Lipoproteins, HDL|ATP-Binding Cassette Transporters|DNA Mutational Analysis|Cholesterol, HDL|Promoter Regions, Genetic|RNA Splicing|Amino Acid Sequence | |
11477070 J. Biol. Chem. 2001 Humans|Rats|Mice|Animals|AR protein, human|*Receptors, Androgen|NIH 3T3 Cells|*Carrier Proteins|Product, Oncogene|PARK7 protein, human|DJ-1 Protein|Androgens|Intracellular Signaling Peptides and Proteins|Protein Binding|Amino Acid Sequence|Signal Transduction|Cell Nucleus|Gene Expression Regulation | |
11477083 J. Biol. Chem. 2001 Humans|*Jaundice, Chronic Idiopathic|P-glycoprotein 2|Iran|HEK293 Cells|*ATP Binding Cassette Transporter, Subfamily B|Multidrug Resistance-Associated Proteins|Membrane Transport Proteins|Exons|Founder Effect|Hyperbilirubinemia|Mutation|Biological Transport|Homozygote|Liver|Phenotype|Base Sequence|Plasma Membrane|Hepatocytes | |
11478682 APMIS 2001 Cattle|Animals|Female|*Estrogen Receptors beta|*Receptors, Estrogen|*Estrogen Receptors alpha|*mRNA|*Reverse Transcriptase Polymerase Chain Reaction|Receptors, Progesterone|Zeranol|*Real Time PCR|Estrogens, Non-Steroidal|Estrogens|Downregulation | |
11478798 Biochem. Biophys. Res. Commun. 2001 Humans|*Transporters, ABC|Exons|Amino Acid Sequence|cDNA|Introns|Base Sequence|mRNA|Sequence Homology, Protein|Cholesterol|Macrophages|Chromosome|Cloning, Molecular|Genome|ABCA6 protein, human | |
11479594 Nat. Genet. 2001 Humans|Child|*Pantothenate Kinase-Associated Neurodegeneration|pantothenate kinase|*Phosphotransferases (Alcohol Group Acceptor)|Brain|Pedigree|Basal Ganglia|Mutation|Neurodegenerative Diseases|Iron | |
11479731 Hum. Genet. 2001 Humans|Male|Child|3-Hydroxy-3-Methylglutaryl-CoA Synthase 2 Deficiency|*Hydroxymethylglutaryl-CoA Synthase|*Mitochondrial Diseases|*Metabolism, Inborn Errors|*Hypoglycemia|Ketone Bodies|Amino Acid Sequence|cDNA|Base Sequence|Mitochondria, Liver|Mitochondria|Liver|Mutations|Testis|Restriction Mapping|Cytosol|Mevalonate | |
11481033 J. Biochem. 2001 src Homology Domains|Protein-Tyrosine Kinases|Syk Kinase|Phosphorylation|Receptors, IgE|Intracellular Signaling Peptides and Proteins|Signal Transduction|Amino Acid Sequence|Enzyme Precursors|Tyrosine | |
11481325 J. Biol. Chem. 2001 Humans|microfibrillar protein|*Tropoelastin|*Fibrillin-1|*Contractile Proteins|*Extracellular Matrix Proteins|Fibrillins|Microfibrils|Elastin|Fibrillin-2|TYRP1 protein, human|*Membrane Glycoproteins|Binding Site|Microfilament Proteins|Glycoproteins|Elastic Tissue|Protein Binding|Recombinant Proteins|Amino Acid Sequence | |
11481335 J. Biol. Chem. 2001 Humans|Mice|Animals|*Diacylglycerol O-Acyltransferase|Acyltransferases|*Mammals|Triglycerides|Amino Acid Sequence|CoA, Acyl|Lipid Metabolism|Phylogeny|Mortierella|Liver|Cloning, Molecular|DGAT2 protein, human | |
11481338 J. Biol. Chem. 2001 Humans|methylmalonyl-coenzyme A racemase|*Genome, Human|*Gene Order|*Racemases and Epimerases|Methylmalonyl CoA Mutase|propionyl-coenzyme A|Acyl Coenzyme A|Amino Acid Sequence|Cloning, Molecular|Sequence Homology, Amino Acid|Escherichia coli|*Prokaryotic Cells | |
11481433 Proc. Natl. Acad. Sci. U.S.A. 2001 PMC55550 *Mycobacterium tuberculosis|methionine sulfoxide reductase|*Escherichia coli|*Nitrogen|*Methionine Sulfoxide Reductase B|Escherichia coli Proteins|Gene Expression Regulation, Bacterial|NOS2 protein, human|Inducible Nitric Oxide Synthase|methionine sulfoxide|Methionine|Bacterial Proteins|Nitrites|Racemethionine|*Protective Agents|*Oxidation-Reduction|Oxidative Stress | |
11481440 Proc. Natl. Acad. Sci. U.S.A. 2001 PMC55518 *Mitogen-Activated Protein Kinases|Transcription, Genetic|Mitogen-Activated Protein Kinase p38|Receptors, Nuclear|RNA, Messenger|Transfection|NCOA1 protein, human|Nuclear Receptor Coactivator 1|Cell Line|Signal Transduction | |
11481447 Proc. Natl. Acad. Sci. U.S.A. 2001 PMC55483 Female|interleukin-22 receptor|*Cytokine Receptor|interleukin-22|*Receptors, Interleukin|Interleukins|IL10 protein, human|IL10|Amino Acid Sequence|mRNA|Sequence Alignment|Sequence Homology, Amino Acid|DNA, Complementary|Cell Lines|Chromosome Mapping|Cloning, Molecular|Cytokines|T Cells | |
11483005 Protein Expr. Purif. 2001 *Mycobacterium tuberculosis|*5-Enolpyruvylshikimate-3-Phosphate Synthase|shikimate kinase|*Phosphotransferases (Alcohol Group Acceptor)|Shikimic Acid|Tuberculosis|Protein Conformation|Amino Acid Sequence|Models, Molecular|Cloning, Molecular|Base Sequence|Phosphate | |
11483508 EMBO J. 2001 PMC149157 Animals|*Dynactin Complex|*Dyneins|*Golgi Complex|Microtubule|Microtubule-Associated Proteins|Nocodazole|Protein Transport|Organelle|Membrane Proteins|Cytoplasm | |
11483511 EMBO J. 2001 PMC149163 Animals|Chlorocebus aethiops|*Kinesin|*Cell Shape|ras-Related GTPases|Cytoskeleton|Immediate-Early Proteins|COS Cells|Microtubules|Actins|Protein Binding|Two-Hybrid System Techniques|Cytoplasm|Calcium Channels | |
11483512 EMBO J. 2001 PMC149153 Mice|Animals|*Glycosylphosphatidylinositol|Saccharomyces cerevisiae|Saccharomyces cerevisiae Proteins|Amino Acid Sequence|Acyltransferases|Aminoacyltransferases|Membrane Glycoproteins|Peptide, Signal|Surface Proteins|Cloning, Molecular|Endoplasmic Reticulum|GAA1 protein, S cerevisiae|GPI8 protein, S cerevisiae | |
11483513 EMBO J. 2001 PMC149141 *Saccharomyces cerevisiae|*ADP,ATP Carrier|Protein, Mitochondrial|Saccharomyces cerevisiae Proteins|Mitochondrial Membrane Transport Proteins|Intracellular Membranes|Membrane Transport Proteins|Mitochondria|Membrane Proteins|*Yeast, Dried|Carrier Proteins|Amino Acid Sequence|Adenosine Diphosphate|Adenosine Triphosphate|TIM10 protein, S cerevisiae|Tim9 protein, S cerevisiae | |
11483758 J. Virol. 2001 PMC115057 *Influenza A virus|RNA Replicase|Virus Replication|Viral Proteins|RNA, Viral|Sequences, Amino Acid|Influenza Viruses|Binding Site|Mutagenesis, Site-Directed|Protein Binding|Mutations|Cell Line | |
11483963 Nat. Cell Biol. 2001 Male|Animals|cohesins|*Chromatids|*Arms|*Chromosomal Proteins, Non-Histone|*Cell Cycle Proteins|Meiosis|Synaptonemal Complex|Chromosome Segregation|Centromere|Nuclear Proteins|Anaphase|Metaphase|Spermatocytes|Phosphoproteins|*Mammals|Fungal Proteins|*Cell Nucleus Division | |
11485553 Biochem. J. 2001 PMC1222033 Animals|*Phosphorylation|Pyruvate Dehydrogenase Complex|Protein Kinase|Protein-Serine-Threonine Kinases|*Oxidation-Reduction|Pyruvate Dehydrogenase Phosphatase|Isoenzymes|Thiamine Pyrophosphate|Binding Sites|Pyruvate Dehydrogenase (Acetyl-Transferring) Kinase|Oxidoreductases|Pyruvates | |
11485562 Biochem. J. 2001 PMC1222042 *Calcium|*Voltage-Dependent Anion Channels|*Mitochondria|Adenine Nucleotide Translocase|Mitochondrial Membrane Transport Proteins|Ion Channels|Intracellular Membranes|Mitochondria, Liver|Mitochondrial Swelling|Cytochromes c|Membrane Proteins|Apoptosis|Liposomes|Permeability | |
11485994 Genes Dev. 2001 PMC312747 Animals|Mice|*Nodal Protein|*Activin Receptor|Transforming Growth Factor beta|*Signal Transduction|Xenopus laevis|Xenopus Proteins|TYRP1 protein, human|Activin Receptors, Type I|Homeodomain Proteins|Mesoderm|Transcription Factors|Body Patterning|Intercellular Signaling Peptides and Proteins|Membrane Proteins|Neoplasm Proteins|Gastrula|Activin Receptors, Type II|GPI-Linked Proteins | |
11485998 J. Biol. Chem. 2001 Humans|*DNA Repair|REV1 protein, human|*Nuclear Proteins|DNA polymerase zeta|DNA-Directed DNA Polymerase|DNA Damage|DNA Replication|Mutagenesis|Saccharomyces cerevisiae|DNA|Mutations|Ultraviolet Rays | |
11486000 J. Biol. Chem. 2001 Animals|Humans|*Phosphorylation|*Pyruvate Dehydrogenase (Acetyl-Transferring) Kinase|*Isoenzymes|Pyruvate Dehydrogenase Complex|Dihydrolipoyllysine-Residue Acetyltransferase|Protein Kinases|Protein-Serine-Threonine Kinases|Kinetics|Acetylation|Binding Sites|Acetyltransferases|Recombinant Proteins|Glucose|*Oxidoreductases|Pyruvates | |
11486021 Mol. Cell. Biol. 2001 PMC87301 *RNA Polymerase II|*Kinetics|transcription factor S-II|Transcriptional Elongation Factors|Transcription Factors, General|*Promoter Regions, Genetic|Transcription, Genetic|Transcription Factors|Base Sequence|Templates, Genetic|RNA|RNA, Messenger | |
11486029 Mol. Cell. Biol. 2001 PMC87309 IL3 protein, human|Interleukin-3|*Cell Proliferation|Glycolysis|Apoptosis|Proto-Oncogene Proteins c-bcl-2|Glucose|Cell Division|*Cell Cycle|Mitochondrion|Cell Death|Cell Survival|3'-(1-butylphosphoryl)adenosine|Hexokinase II|Monosaccharide Transport Proteins|*Carbohydrate Metabolism|Cell Line | |
11486055 Science 2001 Animals|*Hedgehog Proteins|*Lipoylation|Drosophila melanogaster|*Acyltransferases|Signal Transduction|Drosophila Proteins|Wings, Animal|Cholesterol|Membrane Proteins|Palmitates | |
11487608 J. Neurosci. 2001 PMC6763175 RIPK2 protein, human|*Receptor-Interacting Protein Serine-Threonine Kinase 2|*Caspase Activation and Recruitment Domain|*Death Domain|NF-kappa B|*Carrier Proteins|NGF protein, human|Nerve Growth Factor|p75 Neurotrophin Receptor|Signal Transduction|Receptors, Nerve Growth Factor|Adaptor Proteins, Signal Transducing|Receptor-Interacting Protein Serine-Threonine Kinases|Apoptosis|Transcription Factor|Protein Binding | |
11489889 J. Biol. Chem. 2001 Animals|Chlorocebus aethiops|Humans|*Glucosylceramidase|*Bile|*Cloning, Molecular|Sequences, Amino Acid|cDNA|Base Sequence|Blotting, Northern|Sequence Alignment|Open Reading Frame|Sequence Homology, Amino Acid|COS-7 Cells|beta Glucosidase|Bile Acids and Salts|mRNA|Liver | |
11489943 J. Exp. Med. 2001 PMC2193462 Humans|*Herpesvirus 4, Human|*Lymphoproliferative Disease, X-Linked|*Natural Killer Cells|SH2D1A Protein|*B Cells|Signaling Lymphocytic Activation Molecule Family|Receptors, Immunologic|Lymphocyte Activation|Membrane Glycoproteins|Antigens, CD|Carrier Proteins|Intracellular Signaling Peptides and Proteins|Glycoprotein|SH2 Domain|Signal Transduction|SH2D1A protein, human | |
11491531 Immunogenetics 2001 Humans|Mice|Animals|*NK Cell Lectin-Like Receptor Subfamily K|*Ligands|Receptors, Natural Killer Cell|Histocompatibility Antigens Class I|Natural Killer Cells|Protein Binding|CD8-Positive T-Lymphocytes|Carrier Proteins | |
11491658 Antioxid. Redox Signal. 2001 Mice|Animals|*Osmotic Pressure|Proto-Oncogene Proteins c-ret|Multiple Endocrine Neoplasia Type 2a|MEN IIb|*Disulfides|Proto-Oncogene Proteins|Phosphorylation|Dimerization|3T3 Cells|*Osmosis|Drosophila Proteins|*Cytoplasm|Cysteine|Adaptor Proteins, Signal Transducing | |
11493525 Development 2001 Mice|Animals|Prospective Studies|*Hindbrain|retinoic acid receptor gamma|*Receptors, Retinoic Acid|retinoic acid receptor beta|Transcription Factors|Retinoic Acid|Homeodomain Proteins|MafB Transcription Factor|Body Patterning|Retinoic Acid Receptor alpha|Pharyngeal Arches|Avian Proteins|Gene Expression Regulation, Developmental|Oncogene Proteins|Early Growth Response Protein 2|Signal Transduction|*Embryonic Development | |
11493532 Development 2001 Animals|Drosophila melanogaster|*Axin Protein|*Armadillos|*Active Transport, Cell Nucleus|Transcription Factors|Drosophila Proteins|Wnt1 Protein|Armadillo Domain Proteins|*Cytoplasm|Trans-Activators|*Cell Nucleus|Signal Transduction|Drosophila|Repressor Proteins|Proto-Oncogene Proteins|Carrier Proteins|Gene Expression Regulation, Developmental|High Mobility Group Proteins | |
11493599 EMBO Rep. 2001 PMC1083990 Animals|Female|*Drosophila|*Gastrulation|*Complement Factor B|Drosophila Proteins|Drosophila melanogaster|Body Patterning|Serine Endopeptidases|Embryogenesis|Sulfotransferases | |
11493604 J. Biol. Chem. 2001 *Saccharomyces cerevisiae|*Coatomer Protein|*COP-Coated Vesicles|*Golgi Apparatus|*Endoplasmic Reticulum|Saccharomyces cerevisiae Proteins|SNARE Proteins|Vesicular Transport Proteins|*Yeast, Dried|R-SNARE Proteins|Cell Membrane|Biological Transport|Amino Acid Sequence|Carrier Proteins|Mutation | |
11493706 Proc. Natl. Acad. Sci. U.S.A. 2001 PMC55506 Humans|Animals|Dogs|*Cell Polarity|Saccharomyces cerevisiae|Saccharomyces cerevisiae Proteins|Plasma Membrane|Exocytosis|Vesicular Transport Proteins|Green Fluorescent Proteins|Membrane Proteins|Protein Transport|Secretory Vesicles|Amino Acid Sequence|Cytosol|*Cytoplasm|*Mammals|Binding Site|SEC3 protein, S cerevisiae|SEC6 protein, S cerevisiae | |
11493912 Nature 2001 Humans|*Ku Autoantigen|*DNA Repair|*DNA|Antigens, Nuclear|DNA Helicases|DNA-Binding Proteins|Nucleic Acid Conformation|DNA Breaks, Double-Stranded|Nuclear Proteins|Binding Site|Protein Conformation|Base Sequence|Protein Binding|Models, Molecular | |
11493923 Nature 2001 *Signal Transduction Pathway|Mitogen-Activated Protein Kinases|Phosphorylation|ras Proteins|Protein Binding|Transcription Factors|DNA-Binding Proteins|Epidermal Growth Factor|MAP Kinase Signaling System|Repressor Proteins|Protein Structure, Tertiary|Tyrosine Kinase|Carrier Proteins | |
11494123 Oncogene 2001 Animals|Chlorocebus aethiops|*Protein Phosphatase 1|Protein Phosphatase 2A|Phosphorylation|*Proto-Oncogene Proteins|Proto-Oncogene Proteins c-raf|COS Cells|protein phosphatase inhibitor-2|Okadaic Acid|Signal Transduction|Serine|Plasma Membrane|Membrane Microdomains|Enzyme Inhibitors | |
11494148 Oncogene 2001 Humans|*Proto-Oncogene Proteins c-kit|STAT3 protein, human|*STAT3 Transcription Factor|Stem Cell Factor|Signal Transduction Pathways|Transfection|STAT1 protein, human|STAT1 Transcription Factor|Cell Transformation, Neoplastic|Cell Line|Phosphorylation|Cell Division|Codon | |
11495917 J. Biol. Chem. 2001 Animals|*Hedgehog Proteins|*Drosophila|*Protein Kinase|*Transcriptional Activation|Signal Transduction|Drosophila Proteins|Transcription Factor|Kinesin|Drosophila melanogaster|Gene Expression Regulation, Developmental|Repressor Proteins|DNA-Binding Proteins|Protein-Serine-Threonine Kinases|Phosphorylation|PTCH protein, human|Patched-1 Receptor | |
11498055 Neuron 2001 *Dendritic Spines|Synapses|Nerve Tissue Proteins|Receptors, N-Methyl-D-Aspartate|Disks Large Homolog 4 Protein|Dendrites|Homer Scaffolding Proteins|Neuropeptides|Excitatory Postsynaptic Potentials|Neurons|Intracellular Signaling Peptides and Proteins|Hippocampus|Membrane Proteins|Patch-Clamp Techniques|Adaptor Proteins, Signal Transducing|Receptor, Metabotropic Glutamate|Luminescent Proteins|Green Fluorescent Proteins | |
11498534 J. Biol. Chem. 2001 Humans|Chlorocebus aethiops|Animals|*Pyrin|HeLa Cells|Familial Mediterranean Fever|Cytoskeletal Proteins|Caspases|*Cell Death|CARD Signaling Adaptor Proteins|Protein Structure, Tertiary|Protein Binding|Apoptosis|Transfection|COS Cells|MEFV protein, human | |
11498544 Science 2001 Mice|Animals|*Caveolae|CAV1 protein, human|*Caveolin 1|Nitric Oxide Synthase Type III|Nitric Oxide|Signal Transduction|Endothelium, Vascular|*Lungs|Muscle, Smooth, Vascular|Endocytosis | |
11500374 EMBO J. 2001 PMC125574 Animals|Rats|Inositol|Monosaccharide Transport Proteins|Glucose Transport Proteins, Facilitative|*Brain|Membrane Proteins|Neurons|Biological Transport|*Mammals|Active Transport|Symporters|Xenopus laevis|Exocytosis|Amino Acid Sequence|RNA, Messenger | |
11500511 J. Biol. Chem. 2001 JUP protein, human|Plakoglobin|CDH1 protein, human|E Cadherin|Desmosomes|Desmogleins|Desmocollins|Plakophilin 1|Desmoplakins|Desmoglein 1|Cell Membrane|CASP3 protein, human|Caspase 3|Caspases|Cell Adhesion Molecules|Antigens, CD|Apoptosis | |
11500512 J. Biol. Chem. 2001 Animals|Humans|NR1H3 protein, human|*Liver X Receptors|ABCG1 protein, human|*ATP Binding Cassette Transporter, Subfamily G, Member 1|Orphan Nuclear Receptors|*Promoter Regions, Genetic|ATP Binding Cassette Transporter 1|Receptors, Retinoic Acid|Response Elements|Retinoid X Receptors|mRNA|Macrophages|ATP-Binding Cassette Transporters|Transfections|Base Sequence|Cell Line | |
11500517 J. Biol. Chem. 2001 Humans|peroxisomal acyl-CoA oxidase|*Acyl-CoA Oxidase|Peroxisome biogenesis disorders|Peroxisomal Disorders|*Docosahexaenoic Acids|Peroxisomes|Zellweger Syndrome|Enoyl-CoA Hydratase|Oxidoreductases|3-Hydroxyacyl CoA Dehydrogenases|Adrenoleukodystrophy|Oxidation-Reduction|Mitochondria|Multienzyme Complexes|Hydro-Lyases|Fatty Acids|Fibroblasts | |
11502259 Neuron 2001 *Postsynaptic Density Protein 95|*Dendritic Spines|Guanylate Kinase|Synapses|Neurons|NMDA Receptors|Nerve Tissue Proteins|Intracellular Signaling Peptides and Proteins|Hippocampus|Dendrites|Membrane Proteins|GTPase Activating Protein|F-Actin|Brain|Green Fluorescent Proteins|Actin Cytoskeleton | |
11502696 Circulation 2001 Humans|CMA1 protein, human|*Chymases|*Angiotensin II|Angiotensin I|Angiotensin-Converting Enzyme Inhibitors|Captopril|*Arteries|AGT protein, human|Angiotensinogen|Peptidyl-Dipeptidase A|Vasoconstriction|Serine Proteinase Inhibitors|*Serine Proteases|Oligopeptides | |
11502751 J. Biol. Chem. 2001 Animals|inositol hexakisphosphate kinase|*Phosphotransferases (Phosphate Group Acceptor)|inositol pentaphosphate|Inositol Phosphates|Phosphotransferases (Alcohol Group Acceptor)|Amino Acid Sequence|Cytosol|Sequence Homology, Amino Acid|Cloning, Molecular|Cytoplasm|Mammals|Cell Nucleus | |
11502818 J. Clin. Endocrinol. Metab. 2001 Pregnancy|Humans|Female|*Cholesterol Side-Chain Cleavage Enzyme|Lipoid congenital adrenal hyperplasia|Adrenal Hyperplasia, Congenital|*Adrenal Insufficiency|Disorder of Sex Development, 46,XY|*Mutation|*Heterozygote|steroidogenic acute regulatory protein|Phosphoproteins|Disorders of Sex Development|Homozygote|Phenotype|Pregnenolone | |
11504732 J. Biol. Chem. 2001 Humans|Cattle|Animals|Mice|tRNA nucleotidyltransferase|Escherichia coli|*RNA Nucleotidyltransferases|tRNA|*Mitochondria|Amino Acid Sequence|Base Sequence|*Mammals|Substrate Specificity|Kinetics|cDNA|Mitochondria, Liver|Cytoplasm | |
11504915 Proc. Natl. Acad. Sci. U.S.A. 2001 PMC58775 *Phosphatidylinositol 3-Kinase|*Proto-Oncogene Proteins c-akt|MDM2 protein, human|*Proto-Oncogene Proteins c-mdm2|*Cell Nucleus|p53 Tumor Suppressor Protein|*Cytoplasm|Phosphorylation|Proto-Oncogene Proteins|Nuclear Proteins|Serine|Signal Transduction|*Translocation, Genetic|Protein Binding|Mutation|Cell Survival | |
11504941 Proc. Natl. Acad. Sci. U.S.A. 2001 PMC55492 Animals|*Drosophila|Drosophila Proteins|STAT Transcription Factors|Drosophila melanogaster|Janus Kinases|Transcription Factors|DNA-Binding Proteins|Transductions, Signal|Trans-Activators|Gene Expression Regulation, Developmental|Embryo, Nonmammalian|Janus Kinase 1|Glycoproteins|Animals, Genetically Modified | |
11504942 Proc. Natl. Acad. Sci. U.S.A. 2001 PMC55503 HIF1A protein, human|*Hypoxia-Inducible Factor 1, alpha Subunit|*Hydroxylation|*Proline|VHL protein, human|*Von Hippel-Lindau Tumor Suppressor Protein|Nuclear Proteins|Ligases|Amino Acid Sequence|Procollagen-Proline Dioxygenase|Hypoxia|Gene Expression Regulation|Cell Hypoxia | |
11506403 Ann. Neurol. 2001 Humans|Male|Adult|Middle Aged|*Glycolysis|Glycogen Storage Disease XIII|*Glycogen Storage Disease|*Muscular Diseases|*Metabolism, Inborn Errors|Myalgia|Muscle|Enolase|Glycogen|Mutations|Mutations, Missense | |
11507089 J. Biol. Chem. 2001 Rats|Animals|*Phospholipase C gamma2|BTK protein, human|*Bruton Tyrosine Kinase|*Calcium Signaling|*Phosphorylation|*Tyrosine|*Receptors, Antigen, B-Cell|Protein-Tyrosine Kinases|B Cells|Enzyme Activation|Amino Acid Sequence|Phenylalanine|Cell Line|Transfection | |
11507097 J. Biol. Chem. 2001 Animals|Rats|Mice|superoxide dismutase 2|*Mn-Superoxide Dismutase|*Mitochondria|*Superoxide Dismutase, Cu-Zn|Cytosol|Lysosomes|Liver|Zinc | |
11509558 J. Biol. Chem. 2001 *Active Transport, Cell Nucleus|*Nuclear Export Signals|*Cell Nucleus|Cytoplasm|Nuclear Localization Signal|Karyopherins|Transfection|Luminescent Proteins|Amino Acid Sequence|Green Fluorescent Proteins|Protein Structure, Tertiary|Protein Binding|Reporter Gene|Trans-Activators|Cytosol|Plasmids|Leucine|Transcription, Genetic | |
11509569 J. Biol. Chem. 2001 Humans|Mice|Animals|*Fibroblast Growth Factor|*Phosphorylation|*Binding Protein|*Signal Transduction|*Protein Binding|MAPK1 protein, human|Extracellular Signal Regulated Kinase 2|Receptors, Fibroblast Growth Factor|Heparan Sulfate Proteoglycans|Heparitin Sulfate|Receptor Protein-Tyrosine Kinases|Mitogen-Activated Protein Kinases|3T3 Cells|Cell Division|Cell Proliferation|Fibroblasts|Growth Factors|TYRP1 protein, human | |
11509636 J. Immunol. 2001 Humans|Mice|Animals|*Toll-Like Receptor 4|*Fibrinogen|*Mice, Inbred C3H|CCL3 protein, human|Macrophage Inflammatory Protein 1-alpha|*Macrophage|CCL2 protein, human|Monocyte Chemoattractant Protein-1|MIP 1beta|Macrophage Inflammatory Proteins|Chemokines|Monocytes|Toll-Like Receptor 2|Macrophages, Peritoneal|Lipopolysaccharides|Cytokines|Chemokine CCL5|Membrane Glycoproteins | |
11509652 Mol. Cell. Biol. 2001 PMC87326 histone deacetylase 3|*Corepressors|*SMRT Co-repressor|HDAC4 protein, human|*Histone Deacetylases|NCOR1 protein, human|*Nuclear Receptor Co-Repressor 1|Repressor Proteins|DNA-Binding Proteins|Acetylation|Transcription, Genetic|Protein Binding|Amino Acid Sequence|Histone|Cell Nucleus | |
11509732 Science 2001 Animals|Humans|*Anaphase|cohesins|*Separase|*Cytokinesis|*Cell Cycle Proteins|*Chromosomal Proteins, Non-Histone|Saccharomyces cerevisiae|Saccharomyces cerevisiae Proteins|Centromeres|Chromatids|Nuclear Proteins|Phosphoproteins|Endopeptidases | |
11511179 Chem. Res. Toxicol. 2001 Humans|monomethylarsonic acid|*Reductase|Chromatography, Liquid|Tandem Mass Spectrometry|*Arsenicals|GSTO1 protein, human|*Glutathione S Transferase|Arsenic|Methylation|Oxidation-Reduction|Methyltransferases|Liver|Glutathione | |
11511348 Cell 2001 Mice|Animals|*Genes, Homeobox|Somites|Mesoderm|Body Patterning|Gene Expression Regulation, Developmental|Homeodomain Proteins|Receptors, Notch|Basic Helix-Loop-Helix Transcription Factors|Embryo, Mammalian|Avian Proteins|Biological Clocks|Membrane Proteins|Signal Transduction|In Situ Hybridization | |
11511361 Mol. Cell 2001 *Tumor Suppressor Protein p53|*Tetratricopeptide Repeat|EP300 protein, human|*E1A-Associated p300 Protein|p300-CBP Coactivator|Nuclear Proteins|Transcription Factors|Trans-Activators|Cell Cycle Proteins|Proto-Oncogene Proteins c-mdm2|Histone Acetyltransferases|Strap protein|Carrier Proteins|Proto-Oncogene Proteins|Transcriptional Activation|CREB-Binding Protein|Acetylation|Protein Binding | |
11511362 Mol. Cell 2001 *Tumor Suppressor Protein p53|*Apoptosis|TP53INP1 protein, human|*Carrier Proteins|*Heat-Shock Proteins|Phosphorylation|DNA Damage|Tumor Suppressor Proteins|Cell Nucleus|Signal Transduction|Cell Line, Tumor|Transcriptional Activation|Protein Binding|Serine|Cell Death | |
11511374 Mol. Cell 2001 Humans|*Nucleotide Excision Repair|Transcription Factor TFIIH|Xeroderma Pigmentosum|Xeroderma Pigmentosum Group A Protein|DNA Damage|Transcription Factors|Endonucleases|Nuclear Proteins|Ultraviolet Rays|Cell Nucleus | |
11511921 Hum. Genet. 2001 Adult|Humans|Adolescent|*Mucopolysaccharidosis IV|acid beta-galactosidase|*Point Mutation|*beta-Galactosidase|GM1 Gangliosidosis|GLB1 protein, human|*DNA Mutational Analysis|*Mutation|Phenotype|Mutations, Missense | |
11513152 Immunol. Rev. 2001 *Receptors, Natural Killer Cell|KLRD1 protein, human|NK Cell Lectin-Like Receptor Subfamily D|KIR2DL2 protein, human|Receptors, KIR2DL2|Receptors, NK Cell Lectin-Like|LILRB1 protein, human|Leukocyte Immunoglobulin-like Receptor B1|Killer Cell Immunoglobulin-Like Receptors|NK Cell Lectin-Like Receptor Subfamily A|HLA-C*03 antigen|HLA-C Antigens|*Genes, MHC Class I|Lectin, C-Type|Receptors, Immunologic|Histocompatibility Antigens Class I|Antigens, CD|Membrane Glycoproteins | |
11513608 Biochemistry 2001 glutamyl carboxylase|*Factor IX|*Carbon-Carbon Ligases|*Glutamic Acid|Substrate Specificity|Kinetics|Binding Sites|Vitamin K|Peptides|Cell Line|Protein Precursors | |
11514237 Biochim. Biophys. Acta 2001 Rats|Animals|Humans|2,4-dienoyl-CoA reductase|*Reductase|Oxidoreductases Acting on CH-CH Group Donors|Fatty Acid Desaturases|Amino Acid Sequence|Base Sequence|Cloning, Molecular|Microbodies|cDNA|Sequence Homology, Amino Acid | |
11514575 J. Biol. Chem. 2001 Humans|chondroitin synthase|*Cloning, Molecular|*N-Acetylgalactosaminyltransferases|Amino Acid Sequence|Acetylgalactosamine|Chondroitin Sulfates|DNA, Complementary|Heparitin Sulfate|Open Reading Frames|Glucuronic Acid|Sequence Alignment|Recombinant Proteins|Sequence Homology, Amino Acid|Exons|Blotting, Northern|Substrate Specificity|Membrane Proteins | |
11514579 J. Biol. Chem. 2001 *Calnexin|*Molecular Chaperone|*Glycoprotein|Lectins|Calreticulin|Protein Folding|Endoplasmic Reticulum|Binding Sites|Calcium-Binding Proteins|Protein Binding|Membrane Protein|Oligosaccharides|Ribonucleoproteins|Citrate Synthase|Peptides | |
11514595 J. Cell Biol. 2001 PMC2196470 Humans|Animals|*Oxidase|Caenorhabditis elegans|*Peroxidase|*Peroxidases|NADPH Oxidases|*Phagocyte|DUOX1|*Extracellular Matrix|trityrosine|*Tyrosine|ethyl tyrosine ester|Amino Acid Sequence|*Catalysis|Sequence Homology, Amino Acid|DUOX1 protein, C elegans | |
11514627 Mol. Biol. Cell 2001 PMC58605 Humans|*Nuclear Pore|*Amino Acid Substitution|TPR protein, human|*Nuclear Pore Complex Proteins|*Proto-Oncogene Proteins|Nuclear Envelope|Cell Nucleus|Nuclear Proteins|Microscopy, Immunoelectron|Amino Acid Sequence|HeLa Cells|*Dimerization|Recombinant Proteins|*Protein Domains|Electron Microscopy | |
11516400 Neuron 2001 Rats|Cattle|Animals|*Guanine Nucleotide Exchange Factor|inositol hexakisphosphate kinase|*Phosphotransferases (Phosphate Group Acceptor)|1-diphosphoinositol pentakisphosphate|Inositol Phosphates|inositol heptakisphosphate|RASGRF1 protein, human|*ras-GRF1|Chromaffin Cells|Exocytosis|Guanosine 5'-O-(3-Thiotriphosphate)|GTPase|Amino Acid Sequence|Vesicular Transport Proteins|PC12 Cells|Adaptor Proteins, Signal Transducing|Nerve Tissue Proteins | |
11516654 Curr. Biol. 2001 *Phosphorylation|*Threonine|*Endocytosis|Coated Pits, Cell-Membrane|Adaptor Protein Complex 2|Clathrin|Adaptor Protein Complex mu Subunits|Adaptor Protein Complex 1|Adaptor Protein Complex alpha Subunits|Adaptor Protein Complex 3|Clathrin-Coated Vesicles|Adaptor Proteins, Vesicular Transport|Membrane Proteins|Protein Binding|Protein Transport|Transferrin | |
11517213 J. Biol. Chem. 2001 *Clathrin|HIP1 protein, human|*DNA-Binding Proteins|*Endocytosis|Clathrin-Coated Vesicles|*Adaptor Proteins, Signal Transducing|Binding Sites|Carrier Proteins|Protein Binding|HTT protein, human|Huntingtin Protein|Protein Structure, Tertiary|Adaptor Proteins, Vesicular Transport|Amino Acid Sequence|Set2 protein, human|*Histone-Lysine N-Methyltransferase|Heavy Chain, Clathrin|Mutation | |
11517226 J. Biol. Chem. 2001 Humans|Mice|Animals|*Ribonucleotide Reductase|*DNA Damage|DNA Repair|TYRP1 protein, human|TP53 protein, human|Tumor Suppressor Protein p53|S Phase|*Membrane Glycoproteins|Cell Cycle Proteins|Ultraviolet Rays|*Mammals | |
11518510 Dev. Biol. 2001 Humans|Mice|Animals|integrin alpha11beta1|*Receptors, Collagen|*Integrins|*Collagen|*Cell Migration|Cell Adhesion|*Mesenchymal Stem Cells|Collagen Type I|Integrin alpha Chains|Fibroblasts|Extracellular Matrix|Chemotaxis|Cell Line, Tumor|Cartilage|Transfections|cDNA | |
11518528 J. Mol. Biol. 2001 Animals|Humans|PRDX5 protein, human|*Peroxiredoxin 5|TXN protein, human|Thioredoxin|Oxidation-Reduction|Protein Conformation|Amino Acid Sequence|Disulfides|Crystallography, X-Ray|Cysteine|Catalysis|Models, Molecular|Hydrogen Peroxide|Active Site | |
11518718 J. Biol. Chem. 2001 Animals|Mice|*Proteolysis|gamma-Secretase|Aspartic Acid Endopeptidases|Transcription Factors|Presenilin-1|Notch Proteins|Presenilin-2|Amyloid beta-Protein Precursor|Signal Transduction|NOTCH2 protein, human|Receptor, Notch2|Receptor, Notch1|Protein Structure, Tertiary|Protein Processing, Post-Translational|Protein Binding | |
11519011 Am. J. Hum. Genet. 2001 PMC1226055 Humans|3beta-hydroxysterol delta24-reductase|Desmosterolosis|*Oxidoreductases Acting on CH-CH Group Donors|*Nerve Tissue Proteins|Abnormalities, Multiple|Lipid Metabolism, Inborn Errors|Desmosterol|*Mutations|Cholesterol|Phenotype|Oxidoreductases|Exons | |
11520784 Blood 2001 Humans|Mice|Animals|*Phosphatidylinositol 3-Kinase|Phosphatidylinositol 3-Kinases|Signal Transduction|Stem Cell Factor|Proto-Oncogene Proteins c-akt|Phosphorylation|Phosphoinositide-3 Kinase Inhibitors|MAPK3 protein, human|Mitogen-Activated Protein Kinase 3|Proto-Oncogene Proteins c-kit|Chromones|Enzyme Activation|Proto-Oncogene Proteins|MAP Kinase Signaling System|Cell Survival|Receptor Protein-Tyrosine Kinases|Morpholines|Cell Division | |
11520916 Annu. Rev. Neurosci. 2001 PMC2758233 *Neurotrophins|NGFR protein, human|Receptors, Nerve Growth Factor|Neurons|Signal Transduction|Receptor Protein-Tyrosine Kinases|Cell Survival|Cell Differentiation|PI-3 Kinase|*Neurogenesis|Phosphatidylinositol 3-Kinase|Systems, Nervous|Mitogen-Activated Protein Kinases|Cell Death|Synaptic Plasticity|MAP Kinase Signaling System|Nerve Tissue Proteins | |
11520989 Science 2001 Animals|CHUK protein, human|*IkappaB Kinase|*NF-kappa B|*Signal Transduction|I-kappa B Proteins|NF-kappa B kinase|NF kappaB2|Phosphorylation|NF-KappaB Inhibitor alpha|Tumor Necrosis Factor-alpha|Cells, Cultured | |
11522292 FEBS Lett. 2001 Female|Pregnancy|Humans|*Insulin-Like Growth Factor Binding Protein 4|IGFBP5 protein, human|*Insulin-Like Growth Factor Binding Protein 5|*Pregnancy-Associated Plasma Protein-A|*Proteolysis|*Pregnancy-Associated Plasma Protein B|*Cleavers|*Blood Proteins|Recombinant Proteins|Insulin-Like Growth Factor II|Metalloendopeptidases|Amino Acid Sequence|Binding Sites|*Metalloproteases | |
11522655 Cancer Res. 2001 Humans|Mice|Animals|CTNNB1 protein, human|*beta Catenin|Mice, Nude|*Adenomatous Polyposis Coli|*Colon Cancer|*Colon|Genes, APC|Trans-Activators|Adenomatous Polyposis Coli Protein|Signal Transduction|Gene Expression Regulation, Neoplastic|Mutations|Cell Division|Tumor Cells, Cultured|Downregulation | |
11522837 Nucleic Acids Res. 2001 PMC55882 Rats|Animals|mitochondrial transcription factor A|*DNA-Binding Proteins|*Transcription Factors|*Mitochondrial Proteins|*DNA Replication|*Mitochondria|DNA, Mitochondrial|Nuclear Proteins|Transcription, Genetic|Mitochondria, Liver|RNA|Binding Sites|*Mammals | |
11522976 Gastrointest. Endosc. 2001 Humans|*Bile|*Glucuronidase|Cholelithiasis|*Bacteria|bilirubin diglucuronide|Calcium Bilirubinate|Biliary Tract|Enterobacteriaceae|Escherichia coli|Clostridium|Clostridium perfringens | |
11524006 Biochemistry 2001 Humans|*Cystathionine beta-Synthase|*Methionine|*S-Adenosylmethionine|*Racemethionine|Homocystinuria|*Molecular Conformation|Amino Acid Sequence|Cysteine|Kinetics|Heme|Crystallography, X-Ray|*Catalysis|Tryptophan | |
11524432 J. Biol. Chem. 2001 Humans|Cricetinae|Mice|Animals|*Fucosyltransferases|*Fucose|*GDP Fucose|*Epidermal Growth Factor|CHO Cells|Cricetulus|Amino Acid Sequence|Receptors, Notch|Glycosylation|Membrane Proteins|Drosophila|Cell Membrane|*Cloning, Molecular|Ligands|Signal Transduction|Thrombospondin 1|Protein Processing, Post-Translational|PLAGL2 protein, human | |
11528398 Nat. Genet. 2001 Adult|Humans|Distal myopathy, Nonaka type|N-acylmannosamine kinase|UDP acetylglucosamine-2-epimerase|*Distal Myopathies|Phosphotransferases (Alcohol Group Acceptor)|UDP-N-acetylglucosamine 2-epimerase - N-acetylmannosamine kinase|*Multienzyme Complexes|Myositis, Inclusion Body|Carbohydrate Epimerases|Mutations|Homozygote|Muscle, Skeletal|Vacuoles|Genetic Linkage|Haplotypes|India|Bahamas|Georgia | |
11528502 Eur. J. Hum. Genet. 2001 Humans|Methylmalonic acidemia|*Amino Acid Metabolism, Inborn Errors|Methylmalonyl CoA Mutase|Mutation|Phenotype|Methylmalonic Acid|Homozygotes|Mutagenesis|Missense Mutation|Apoenzyme | |
11529500 Cell. Mol. Life Sci. 2001 PMC1424219 Animals|*trans-Golgi Network|*Protein Sorting|Transport Vesicles|Secretory Pathway|Proteins|Cell Membrane|Lipid Metabolism|Lipids | |
11530204 Biochimie 2001 Humans|neolactotetraosylceramide alpha-2,3-sialyltransferase|N-acetyllactosaminide alpha-2,3-sialyltransferase|*Sialyltransferases|Cloning, Molecular|Amino Acid Sequence|Base Sequence|Glycolipids|cDNA|Glycoproteins|Substrate Specificity|Gene Expression Regulation, Enzymologic | |
11532276 Mol. Immunol. 2001 MBL2 protein, human|*Mannose-Binding Lectin|*Complement Activation|MASPs|Collectins|Lectins|Carrier Proteins|Serine Endopeptidases|Protein Binding|Blood Proteins|Amino Acid Sequence | |
11532455 FEBS Lett. 2001 Humans|*Aquaporin 1|Escherichia coli Proteins|Protein Conformation|Crystallography, X-Ray|Models, Molecular|Bacterial Outer Membrane Proteins|Escherichia coli|Cell Membrane Permeability|Structure-Activity Relationship|Glycerol|Water|Biological Transport|GlpF protein, E coli|Aquaporins | |
11532919 Development 2001 Animals|*Cactus|Drosophila|Drosophila Proteins|DNA-Binding Proteins|Nuclear Proteins|Drosophila melanogaster|NF-kappa B|Phosphoproteins|Signal Transduction Pathway|I kappa B Proteins|Binding Sites|Cell Nucleus|RELA protein, human|Transcription Factor RelA|Amino Acid Sequence | |
11532940 EMBO J. 2001 PMC125596 Humans|FLT4 protein, human|*Vascular Endothelial Growth Factor Receptor-3|*Vascular Endothelial Growth Factor C|Vascular Endothelial Growth Factor A|*Endothelial Cells|FLT1 protein, human|*Vascular Endothelial Growth Factor Receptor-1|*Lymphatic Endotheliums|VEGFD protein, human|VEGF-D|Vascular Endothelial Growth Factors|Receptors, Vascular Endothelial Growth Factor|Receptor Protein-Tyrosine Kinases|Receptors, Growth Factor|Neovascularization, Physiologic|Endothelium, Vascular|Signal Transduction|Lymphatic System | |
11532953 EMBO J. 2001 PMC125270 Humans|Animals|*Chromatin Assembly and Disassembly|TTF1 protein, human|Transcription Factors|SMARCA5 protein, human|Chromosomal Proteins, Non-Histone|BAZ1A protein, human|Adenosine Triphosphatases|Chromatin|DNA-Binding Proteins|Histone H4|Nuclear Proteins|Transcription, Genetic|Nucleosomes|rDNA|Promoter Regions, Genetic|Cell Nucleolus|RNA Polymerase I|Protein Binding | |
11532957 EMBO J. 2001 PMC125268 Animals|*Transcriptional Activation|CTNNB1 protein, human|*beta Catenin|*Chromatin Assembly and Disassembly|SMARCA4 protein, human|*Transcription Factors|*Nuclear Proteins|*DNA Helicases|DNA-Binding Proteins|Trans-Activators|TCF Transcription Factors|Promoter Regions, Genetic|Transcription, Genetic|Wnt Proteins|Reporter Gene|Binding Sites|Transfection|Cell Nucleus | |
11532962 EMBO J. 2001 PMC125616 *Nonsense Mediated mRNA Decay|RNA Splicing|Spliceosomes|*Cell Nucleus|Exon|Ribonucleoproteins|mRNA|*Active Transport, Cell Nucleus|RNA-Binding Proteins|Cytoplasm|Nuclear Proteins|*RNA Transport|Binding Site | |
11532985 Hum. Mol. Genet. 2001 Humans|DYSF protein, human|*Dysferlin|*Caveolin 3|*Muscle, Skeletal|Dystrophy, Muscular|Membrane Protein|Muscle Proteins|Sarcolemma|Caveolins|Limb-girdle muscular dystrophy, type 2B|Muscular Dystrophies, Limb-Girdle|Caveolae|Muscular Dystrophy, Limb-Girdle, Type 1C|Mutations | |
11532990 Hum. Mol. Genet. 2001 Animals|Chlorocebus aethiops|*Clathrin|*Adaptor Protein Complex alpha Subunits|*Binding Protein|HTT protein, human|*Huntingtin Protein|*Endocytosis|Clathrin-Coated Vesicles|DNA-Binding Proteins|Protein Binding|Binding Sites|Amino Acid Sequence|Protein Structure, Tertiary|Actin|COS Cells|Cell Membrane|Protein Transport | |
11533026 J. Biol. Chem. 2001 Animals|Mice|Humans|*Receptors, Netrin|Caenorhabditis elegans|*Phosphorylation|HEK293 Cells|netrin-2|*Netrin|Caenorhabditis elegans Proteins|Receptors, Cell Surface|NTN1 protein, human|Netrin 1|Growth Cones|Receptors, Growth Factor|PTPN11 protein, human|*Tyrosine Phosphatase, Shp-2|Helminth Proteins|Nerve Tissue Proteins|Membrane Proteins|Axons | |
11535616 J. Cell Biol. 2001 PMC2196190 Humans|*Anaphase-Promoting Complex-Cyclosome|*HeLa Cells|*Cell Cycle Proteins|Mad2 Proteins|Kinetochores|Mitosis|Protein-Serine-Threonine Kinases|Cdc20 Proteins|Mitotic Checkpoint|Spindle Apparatus|Nuclear Proteins|Protein Kinases|Calcium-Binding Proteins|Repressor Proteins|Poly-ADP-Ribose Binding Proteins|Ubiquitin|BUB3 protein, human|CDC20 protein, human | |
11536079 Am. J. Hum. Genet. 2001 PMC1226061 Humans|*Pseudoxanthoma Elasticum|ABCC6 protein, human|*Multidrug Resistance-Associated Proteins|*Mutations|DNA Mutational Analysis|Alleles|Exons|Pedigree|Polymorphism, Genetic|Codon, Nonsense|Amino Acid Sequence|Phenotype|Mutation, Missense|Cohort Studies | |
11536331 J. Neurosci. Res. 2001 Animals|tropomyosin-related kinase-B, human|*Receptor, trkB|*Macaque|*Dimerization|*Cortex, Prefrontal|Brain-Derived Neurotrophic Factor|*Membrane Glycoproteins|Monkey|RNA, Messenger | |
11544178 Genes Dev. 2001 PMC312772 Mice|Animals|Hox Gene|Homeodomain Proteins|*Biological Evolution|Transcription Factors|*Animals, Genetically Modified|Gene Expression Regulation, Developmental|Limbs|Morphogenesis|Multigene Family|Vertebrates|Phenotype|Mutation|*Cluster Analysis | |
11544179 Genes Dev. 2001 PMC312771 Animals|Humans|*Nonsense Mediated mRNA Decay|*Protein Kinase|*Phosphatidylinositol 3-Kinase|SMG1 protein, human|*Phosphatidylinositol 3-Kinases|Phosphorylation|Termination Codons, Premature|Caenorhabditis elegans|mRNA|Protein-Serine-Threonine Kinases|RNA Helicases|Trans-Activators|Carrier Proteins|*Biochemical Phenomena|SMG-1 protein, C elegans|Caenorhabditis elegans Proteins | |
11544254 J. Biol. Chem. 2001 Humans|Chlorocebus aethiops|Animals|Mice|NECTIN2 protein, human|NECTIN1 protein, human|*Nectins|afadin|*Cell Adhesion Molecules|*Microfilament Proteins|poliovirus receptor|Receptors, Virus|Cadherins|Junctions, Adherens|Cell Adhesion|COS Cells|Transfection|Protein Binding|Amino Acid Sequence|Kinesin | |
11544482 Nat. Neurosci. 2001 *Neurotrophins|MAPK7 protein, human|*Mitogen-Activated Protein Kinase 7|*Signal Transduction|MAPK3 protein, human|Mitogen-Activated Protein Kinase 3|Receptors, Neurotrophin|Phosphorylation|MAP Kinase Signaling System|Neurons|Receptor Protein-Tyrosine Kinases|Protein Transport|Cell Nucleus|Endocytosis | |
11544529 Nature 2001 Humans|*Toll Like Receptor 4|*Myeloid Differentiation Factor 88|*Signal Transduction|*Adaptor Proteins, Signal Transducing|Toll-Like Receptors|Receptors, Interleukin-1|NF-kappa B|Receptors, Immunologic|Toll-Like Receptor 2|Lipopolysaccharides|Membrane Glycoproteins|Interleukin-1 Receptor-Associated Kinases|Antigens, Differentiation|Drosophila Proteins|Dendritic Cells|Gene Expression Regulation | |
11545733 Mol. Cell 2001 Humans|*Osteogenesis|*Retinoblastoma Protein|*Transcription Factor|*Cell Differentiation|Osteoblast|Core Binding Factor Alpha 1 Subunit|Bone Morphogenetic Protein 2|Promoter Regions, Genetic|Retinoblastoma-Like Protein p107|Transforming Growth Factor beta|Phosphoproteins|Transcriptional Activation|Gene Expression Regulation|Osteocalcin|Neoplasm Proteins|Cell Line | |
11545734 Mol. Cell 2001 Humans|Mice|Animals|*Tumor Suppressor Protein p53|PTEN protein, human|*PTEN Phosphohydrolase|Genes, Tumor Suppressor|Proto-Oncogene Proteins c-mdm2|Proto-Oncogene Proteins|Signal Transduction|Proto-Oncogene Proteins c-akt|Phosphatidylinositol 3-Kinases|Nuclear Proteins|Tumor Cell Lines|DNA Damage|Apoptosis|Transfection | |
11546776 J. Biol. Chem. 2001 Animals|Cricetinae|Humans|*Receptor, ADP|2-methylthio-ATP|Thionucleotides|methylthio-ADP|Adenosine Diphosphate|MAPK3 protein, human|Mitogen-Activated Protein Kinase 3|MAPK1 protein, human|Mitogen-Activated Protein Kinase 1|Phosphorylation|Cyclic AMP|Adenosine Triphosphate|Amino Acid Sequence|CHO Cells|Signal Transduction|Forskolin | |
11546806 J. Biol. Chem. 2001 Humans|Male|*Interleukin-2|*Testis|*Tumor Suppressor Protein p53|Protein Kinase|Phosphorylation|*Myosin-Light-Chain Kinase|Protein-Serine-Threonine Kinases|Amino Acid Sequence|Cell Cycle|Cloning, Molecular|Base Sequence|Gene Library|*Tumor Cell Lines|*T-Lymphocytes, Cytotoxic|DNA, Complementary|Transfection|Cell Division|Epithelial Cells | |
11546808 J. Biol. Chem. 2001 Humans|*Nuclear Pore|*Cytosol|*ERK MAP Kinases|Nuclear Import|Cell Nucleus|*Protein Transport|Importin-beta|Phosphorylation|Cytoplasm|Transductions, Signal|HeLa Cells|Digitonin|Diffusion | |
11546814 J. Biol. Chem. 2001 Animals|Humans|*Saccharomyces cerevisiae|PTS2 Protein|Peroxisomes|Peroxisome-Targeting Signal 1 Receptor|Saccharomyces cerevisiae Proteins|Peroxins|Two-Hybrid System Techniques|Receptors, Cytoplasmic and Nuclear|Carrier Proteins|Amino Acid Sequence|Protein Transport|Isoforms|Mutation|Protein Binding | |
11546872 Science 2001 Animals|*Anoikis|*Actins|MYO5A protein, human|*Myosin Type V|Proteins, BCL2|Apoptosis Regulatory Proteins|Bcl-2-Like Protein 11|Proto-Oncogene Proteins|Adaptor Proteins, Signal Transducing|Membrane Proteins|Carrier Proteins|Myosin Heavy Chains|Amino Acid Sequence|Protein Binding|*Actin Cytoskeleton | |
11546874 Science 2001 Humans|Animals|*Exon|RNA Splicing|mRNA|RNA-Binding Proteins|Ribonucleoproteins|3' Untranslated Region|Nonsense Mediated mRNA Decay|Termination Codons, Premature|Nuclear Proteins|Export, Nuclear|RNPS1 protein, human | |
11551508 Cell 2001 Animals|*mRNA|*Nonsense Mediated mRNA Decay|Cap Binding Protein|Nuclear Cap-Binding Protein Complex|EIF4E|messenger ribonucleoprotein|Ribonucleoproteins|EIF-4G|Protein Biosynthesis|Codon, Nonsense|Cytoplasm|Cell Nucleus | |
11551930 J. Biol. Chem. 2001 Humans|TP53 protein, human|*Tumor Suppressor Protein p53|polo-like kinase 1|PLK3 protein, human|Cell Cycle Proteins|*DNA Damage|Cell Cycle|*Cell Cycle Arrest|*Apoptosis|Phosphorylation|Mitosis|Proto-Oncogene Proteins|Checkpoint Kinase 2|Protein Kinases|Serine|HeLa Cells|Transfection | |
11551958 J. Biol. Chem. 2001 Humans|Cricetinae|Mice|Animals|galactosylxylosylprotein 3-beta-galactosyltransferase|*Glycosaminoglycans|Drosophila melanogaster|N-acetyllactosaminide alpha-1,3-galactosyltransferase|*Galactosyltransferases|Amino Acid Sequence|Caenorhabditis elegans|Base Sequence|DNA, Complementary|Cloning, Molecular|Sequence Homology, Amino Acid|Heparitin Sulfate|CHO Cells|*Genetic Linkage|Chondroitin Sulfates | |
11553796 Proc. Natl. Acad. Sci. U.S.A. 2001 PMC58725 Animals|Rats|*Wiskott-Aldrich Syndrome Protein, Neuronal|*Actin|Cytoskeletal Proteins|Actin-Related Protein 3|Binding Proteins|Actin-Related Protein 2|Nerve Tissue Proteins|Amino Acid Sequence|Actin Cytoskeleton|Phosphoproteins|*Brain|proline transport protein|*Amino Acid Transport Systems, Neutral|Pseudopodia|Protein Binding|Proline | |
11554294 Prog. Nucleic Acid Res. Mol. Biol. 2001 Animals|*DNA Ligases|*Base Excision Repair|LIG3 protein, human|DNA Ligase III|XRCC1 protein, human|X-ray Repair Cross Complementing Protein 1|Pol beta protein, human|DNA Polymerase beta|Poly-ADP-Ribose Binding Proteins|Proliferating Cell Nuclear Antigen|DNA Damage|DNA Replication|Poly ADP Ribose Polymerase|PARP1 protein, human|Poly (ADP-Ribose) Polymerase-1|DNA-Binding Proteins|*Mammals|Xenopus Proteins | |
11555634 Hum. Mol. Genet. 2001 *Refsum Disease|phytanoyl-coenzyme A|Coenzyme A|Phytanic Acid|2-Oxoglutarate|*Mutations|Mixed Function Oxygenases|Oxidation-Reduction|Peroxisomes|Hydroxylation|Mutagenesis, Site-Directed|Catalysis | |
11555793 Am. J. Hum. Genet. 2001 PMC1274356 Child|Female|Humans|Arginine-Glycine Amidinotransferase Deficiency|glycine amidinotransferase|*Creatine|*Arginine|*Amidinotransferases|Amino Acid Metabolism, Inborn Errors|Mental Retardation|Speech Disorders|Developmental Disabilities|Guanidinoacetate N-Methyltransferase|glycocyamine|Glycine|Brain|*Metabolic Clearance Rate | |
11555828 Metab. Clin. Exp. 2001 Humans|CYP1A1 protein, human|*Cytochrome P-450 CYP1A1|*Hydroxylation|CYP1A2 protein, human|CYP1A2|CYP1B1 protein, human|Cytochrome P-450 CYP1B1|Cytochrome P450|*Estradiol|Steroid 16-alpha-Hydroxylase|Microsomes, Liver|CYP3A4|Cytochrome P-450 CYP2C8|Cytochrome P-450 CYP2C9 | |
11556966 Tissue Antigens 2001 Humans|*Chromosome 17|Intron|Exons|Base Sequence|Chromosome Mapping|Amino Acid Sequence|Pseudogene|Cloning, Molecular|5' Untranslated Region|*Signal Transduction|3' Untranslated Region|Multigene Family | |
11557037 FEBS Lett. 2001 *Insulin Receptor Substrate-1 Protein|*Phosphorylation|*Surface Plasmon Resonance|*Receptor, IGF Type 1|IGF1 protein, human|Insulin-Like Growth Factor I|IGF1R protein, human|Phosphoproteins|Signal Transduction|Insulin|Protein Binding|*Biosensor | |
11557983 Nature 2001 Animals|Chlorocebus aethiops|ABI1 protein, human|Adaptor Proteins, Signal Transducing|*Protein Binding|*Ephrins|ABI2 protein, human|Signal Transduction|Phosphorylation|src Homology Domain|Eph Receptor Tyrosine Kinase|Receptor, EphB2|Cytoskeleton|Cytoskeletal Proteins|Membrane Proteins|Ephrin-B2|PXN protein, human|Paxillin|Phosphotyrosine|COS Cells | |
11559530 Cancer Res. 2001 *Tumor Suppressor Protein p53|APAF1 protein, human|Apoptotic Protease-Activating Factor 1|*Apoptosis|OF-1 protein|DNA-Binding Proteins|*DNA Damage|Activation, Transcriptional|Transcription Factors|Cell Cycle Proteins|cDNA Microarray|Transcription, Genetic|Binding Sites|mRNA|Promoter Regions, Genetic|*Complement Factor B|*Cell Death | |
11560503 Biochemistry 2001 *Haem|*eIF-2alpha Kinase|*Phosphorylation|*Dimerization|Hemin|Protein Binding|Reticulocytes|Recombinant Proteins|Mutagenesis, Site-Directed|Threonine|Protein Biosynthesis|Escherichia coli|Tyrosine | |
11561168 Curr. Opin. Lipidol. 2001 Chlorocebus aethiops|Animals|high density lipoprotein receptors|Lipoproteins, HDL|Scavenger Receptors, Class B|CD36 Antigens|Receptors, Immunologic|Cholesterol|Cholesterol Esters|Cholesterol, HDL|Plasma Membrane|Biological Transport|COS Cells|Liver|Cell Polarity | |
11562357 J. Biol. Chem. 2001 Mice|Animals|nephrin|NPHS2 protein|*Membrane Proteins|*Intracellular Signaling Peptides and Proteins|CD2-associated protein|Cytoskeletal Proteins|Nephrosis, congenital|Nephrotic Syndrome|Adaptor Proteins, Signal Transducing|Podocyte|*Signal Transduction|Kidney Glomerulus|Proteinuria|Mutations | |
11562423 Mol. Pharmacol. 2001 Animals|Cricetinae|Humans|melanin-concentrating hormone receptor|CHO Cells|Cricetulus|*Receptors, Pituitary Hormone|GPRC5C protein, human|Receptors, G-Protein-Coupled|Base Sequence|Somatostatin Receptor|Amino Acid Sequence|cDNA|Signal Transduction|Cloning, Molecular|Transfection|Sequence Homology, Amino Acid|RNA, Messenger | |
11562789 J. Membr. Biol. 2001 Sodium-Bicarbonate Cotransporter|CFTR protein, human|Cystic Fibrosis Transmembrane Conductance Regulator|Anion Exchanger 4|Bicarbonates|Tubule, Proximal Kidney|Kidney|Cloning, Molecular|Isoforms|Epithelial Cells|*Ions|Homeostasis | |
11563835 Biochem. Biophys. Res. Commun. 2001 Humans|Mice|Animals|*Wnt Signaling Pathway|FZD2 protein, human|Frizzled Receptors|FZD1 protein, human|CTNNB1 protein, human|beta Catenin|Wnt Proteins|*Heterotrimeric G-Proteins|G-Protein-Coupled Receptors|Trans-Activators|Proto-Oncogene Proteins|Cell Membrane Proteins|Protein Binding|Zebrafish Proteins|Ligands|Models, Biological | |
11563910 J. Mol. Biol. 2001 Humans|Animals|VPS4A protein, human|Endosomal Sorting Complexes Required for Transport|Saccharomyces cerevisiae|Saccharomyces cerevisiae Proteins|*Protein Transport|Endosomes|ATPases Associated with Diverse Cellular Activities|Carboxypeptidase Y|Vacuolar Proton-Translocating ATPases|Amino Acid Sequence|Sequence Homology, Amino Acid|Invertase|VPS4 protein, S cerevisiae|Adenosine Triphosphatases | |
11563989 Biochem. J. 2001 PMC1222141 Humans|glycoprotein 340|*Agglutinins|*Receptors, Immunologic|DMBT1 protein, human|*Receptors, Cell Surface|*Scavenger Receptor|*Surfactant Protein D|agglutinin-B|*Lectins|Streptococcus mutans|Western Blotting|Glycoprotein|Amino Acid Sequence|Saliva|SDS PAGE|Submandibular Gland|Bronchoalveolar Lavage Fluid|Surface-Active Agents | |
11564718 Endocrinology 2001 Animals|Humans|*Glucagon-Like Peptide 1|Enteroendocrine Cells|Proglucagon|Glucagon|Gastric Inhibitory Polypeptide|Protein Precursors|Intestine|Peptide Fragments|Insulin|Cell Line|Gastrin Releasing Peptide|Gene Expression|Carbachol|Transcription Factors|Oleic Acid|*B Cells|Palmitic Acid | |
11564734 J. Biol. Chem. 2001 Female|Pregnancy|Cricetinae|Humans|Animals|*Collectin|*Endothelial Cells|CHO Cells|Cricetulus|oxidized low density lipoprotein|Lipoproteins, LDL|Receptors, Immunologic|acetyl-LDL|Amino Acid Sequence|Scavenger Receptors, Class A|Scavenger Receptors, Class B|cDNA|*Placenta|Umbilical Vein|*Membrane|Phagocytosis|Cloning, Molecular | |
11564763 J. Immunol. 2001 interleukin-20 receptor|interleukin 20|Receptors, Interleukin|*Interleukins|interleukin-24|interleukin-22 receptor|IL19 protein, human|*Signal Transduction|IL10 protein, human|IL10|STAT3 Transcription Factor|Trans-Activators|*Protein Binding|STAT1 Transcription Factor|Phosphorylation|Binding Sites | |
11564764 J. Immunol. 2001 HGF protein, human|*Hepatocyte Growth Factor|*Interleukin-7|interleukin-7 receptor, alpha chain|Receptors, Interleukin-7|CXCL12 protein, human|Chemokine CXCL12|Stromal Cell|Cell Differentiation|Bone Marrow Cells|Cells, Cultured|B-Lymphocytes|Bone Marrow Transplantation | |
11564780 J. Immunol. 2001 Humans|Mice|Animals|*Cell Adhesion Molecules|SH2D1A protein, human|Signaling Lymphocytic Activation Molecule Associated Protein|Antigens, CD|Signaling Lymphocytic Activation Molecule Family|B-Lymphocytes|Membrane Glycoproteins|Lymphocyte Activation|Carrier Proteins|Protein Binding|Monocytes|Lymphoproliferative Disease, X-Linked|Amino Acid Sequence|Transcription Factors|Intracellular Signaling Peptides and Proteins|Epitopes|Ligands|Immunoglobulin Domains | |
11564866 Mol. Cell. Biol. 2001 PMC99859 Humans|U937 Cells|*Chromatin Immunoprecipitation|*Promoter Regions, Genetic|Binding Sites|DNA-Binding Proteins|Chromatin|E2F Transcription Factors|Cell Cycle Proteins|E2F1 Transcription Factor|Transcription, Genetic|DNA|Protein Binding|*Cells, Cultured|S Phase|Base Sequence|mRNA|Transcriptional Activation|Transfection | |
11566133 Structure 2001 PMC4030376 Humans|*Histamine N-Methyltransferase|*Kinetics|Protein Conformation|Models, Molecular|Amino Acid Sequence|Polymorphism, Genetic|Proteins|Phenotypes|Histamine | |
11566266 Matrix Biol. 2001 *Angiopoietins|Angiopoietin-1|Receptor, TIE-2|Angiopoietin-2|Receptors, TIE|*Signal Transduction|Receptor Protein-Tyrosine Kinases|Endothelial Growth Factors|Neoplasm Proteins|Proto-Oncogene Proteins|Vascular Endothelial Growth Factor A|Membrane Glycoproteins|Endothelium, Vascular|Cell Division|RNA, Messenger|Cell Migration | |
11566863 Development 2001 Humans|Chick Embryo|Animals|Mice|*Transcription Factors|*Hindbrain|Homeodomain Proteins|Hox Genes|MAFB protein, human|MafB Transcription Factor|Binding Sites|Enhancer Elements, Genetic|Gene Expression Regulation, Developmental|Transgenic Mouse|*Vertebrate|Xenopus Proteins|Base Sequence|Sequence Homology, Nucleic Acid|HOXA3 protein, human|HoxB3 protein, human|Hoxa3 protein, mouse | |
11566871 EMBO J. 2001 PMC125626 Humans|citrin|*Aspartic Acid|*Glutamate-Aspartate Transporter|*Calcium-Binding Proteins|*Organic Anion Transporters|*Mitochondria|Adult-onset citrullinemia type 2|Citrullinemia|Mitochondrial Membrane Transport Proteins|Mitochondrial Proteins|aspartate-glutamate carrier|Amino Acid Transport Systems, Acidic|Antiporters|Membrane Transport Proteins|Glutamate|Isoforms|Calcium | |
11566882 EMBO J. 2001 PMC125629 Animals|ATP dependent 26S protease|*Proteasome Endopeptidase Complex|*Catalytic Domain|ubiquitin-aldehyde|Ubiquitins|ubiquitin-Nalpha-protein hydrolase|Endopeptidases|ubiquitin vinyl sulfone|Saccharomyces cerevisiae|Saccharomyces cerevisiae Proteins|Ubiquitin C-Terminal Hydrolase|Amino Acid Sequence|*Cytoplasm|Sulfones | |
11567032 J. Biol. Chem. 2001 Mice|Animals|*Sterol Regulatory Element Binding Proteins|Sterol Regulatory Element Binding Protein 1|CCAAT-Enhancer-Binding Proteins|mRNA|Liver|Transcription, Genetic|Mice, Transgenic|*Mammals|cDNA|Acids, Fatty|Acetyl-CoA Carboxylase|Stearoyl CoA Desaturase|Cell Nucleus|Fatty Acid Synthases|Sterols | |
11567222 Hum. Pathol. 2001 Male|Humans|Mice|Animals|*Prostate|Prostatic Intraepithelial Neoplasia|*Prostate Cancer|Adenocarcinoma|Gene Expression Regulation, Neoplastic|Transcription Factor, EGR1|Carcinoma|Co-Repressor Proteins|NAB2 protein, human|Repressor Proteins|EGR1 protein, human|Nab2 protein, mouse|Neoplasm Proteins | |
11568288 Pediatr. Res. 2001 Infant, Newborn|Infant|Humans|Animals|Female|*Glucuronidase|*Aspartic Acid|Kinetics|Breast Milk|casein hydrolysate|Casein|Jaundice, Neonatal|Infant Food|Milk Proteins|Bilirubin|Food, Formulated|Hydrolysis | |
11571266 EMBO Rep. 2001 PMC1084076 TNFSF13 protein, human|*Furin|*Tumor Necrosis Factor Ligand Superfamily Member 13|*Golgi Apparatus|TNFSF13B protein, human|B-Cell Activating Factor|TACI Receptor|Protein Binding|*Biological Transport|Cell Membrane|Brefeldin A|Endoplasmic Reticulum|Ligands|Subtilisins|Protein Structure, Tertiary|Cell Line|Tumor Necrosis Factor-alpha|Protein Transport | |
11571269 EMBO Rep. 2001 PMC1084079 Humans|RAD52 protein, human|*Rad52 DNA Repair and Recombination Protein|Saccharomyces cerevisiae|DNA Repair|Saccharomyces cerevisiae Proteins|Rad51 Recombinase|Recombination, Genetic|DNA, Single-Stranded|DNA Damage|DNA-Binding Proteins|DNA|DNA Replication|Protein Binding|Meiosis|Exonucleases|RAD52 protein, S cerevisiae | |
11571274 J. Biol. Chem. 2001 Mice|Animals|*Phosphorylation|H2AX protein, human|*Histones|PRKDC protein, human|DNA-Dependent Protein Kinase|*DNA Breaks, Double-Stranded|Cell Cycle Proteins|Ataxia Telangiectasia Mutated Proteins|Tumor Suppressor Proteins|DNA Damage|Ataxia-Telangiectasia|DNA-Binding Proteins|Nuclear Proteins|Cell Lines|Serine|DNA | |
11571290 J. Biol. Chem. 2001 *Bone Morphogenetic Proteins|Smad Proteins|DNA-Binding Proteins|Smad1 Protein|Bone Morphogenetic Protein Receptors|Trans-Activators|Transforming Growth Factor beta|BMP Type I Receptor|Transductions, Signal|Protein-Serine-Threonine Kinases|Bone Morphogenetic Protein 2|Receptors, Growth Factor|ornithine decarboxylase antizyme|Transcription, Genetic|Gene Expression Regulation|Phosphorylation|Protein Binding | |
11571653 Oncogene 2001 *Tumor Suppressor Protein p14ARF|*Cyclin-Dependent Kinase Inhibitor p16|*Germ-Line Mutation|Melanoma, Cutaneous Malignant|*Melanoma|Skin Neoplasms|*Exon|Genes, p16|Mutations|Pedigree|Genetic Predisposition to Disease|Genes, Tumor Suppressor|Proteins | |
11572855 J. Biol. Chem. 2001 Humans|Cricetinae|Animals|*Integrins|Receptors, Collagen|*Collagen|laminin 1|Laminin|Integrin alpha1|Integrin alpha2|Cell Adhesion|Protein Binding|Recombinant Proteins|CHO Cells|Ligands|Binding Sites|Protein Structure, Tertiary|Amino Acid Sequence|Mutagenesis, Site-Directed|Recombinant Fusion Proteins|Antigens, CD | |
1157293 Clin. Biochem. 1975 Infant, Newborn|Humans|Adult|*Bilirubin|Kernicterus|Jaundice, Neonatal|Hyperbilirubinemia, Neonatal|Serum Albumin|Protein Binding|Chromatography|Human Serum Albumin | |
11572983 Proc. Natl. Acad. Sci. U.S.A. 2001 PMC58727 Apoptosis|Proto-Oncogene Proteins c-bcl-2|*Cell Death|Apoptosis Regulatory Proteins|Tumor Suppressor Protein p53|Binding Sites|Proto-Oncogene Proteins|DNA Damage|Protein Binding|Mitochondria|Transcription Factors|mRNA|Gene Expression Regulation|Amino Acid Sequence|Oligonucleotide Array Sequence Analysis | |
11573085 Nat. Struct. Biol. 2001 Humans|Female|BRCA1 protein, human|BRCA1 Protein|*Dimerization|Tumor Suppressor Proteins|Ubiquitin-Protein Ligases|Carrier Proteins|*Cell Nucleus|Amino Acid Sequence|Ubiquitination|Genes, Tumor Suppressor|Mutations|Sequence Homology, Amino Acid|Zinc Fingers|Ovarian Cancer|BARD1 protein, human | |
11573934 Biochem. Biophys. Res. Commun. 2001 Humans|Animals|*Jejunum|*Aquaporins|Amino Acid Sequence|Cloning, Molecular|Base Sequence|Biological Transport|*Duodenum|Glycerol|DNA, Complementary|In Situ Hybridization|Sequence Homology, Amino Acid|Xenopus laevis|mRNA|Osmosis|Water|Oocytes|Northern Blotting | |
11574155 Gene 2001 Humans|Rats|Male|Animals|Mice|GPR17 protein, human|G-Protein-Coupled Receptors|Receptors, Cell Surface|Cloning, Molecular|GTP-Binding Proteins|Amino Acid Sequence|DNA, Complementary|Chromosome Mapping|Gene Expression|Ligands|mRNA|Tissue Distributions|Pseudogene|Sequence Homology, Amino Acid|Brain|GPR17 protein, mouse|Nerve Tissue Proteins|Gpr26 protein, rat | |
11574464 EMBO J. 2001 PMC125646 Humans|IL17A protein, human|IL17F protein, human|*Interleukin-17|*Cystine|Receptors, Interleukin-17|*Protein Binding|*Cytokines|Receptors, Interleukin|Amino Acid Sequence|Sequence Alignment|Conserved Sequence|Sequence Homology, Amino Acid|Dimerization|Crystallography, X-Ray|Disulfides|Models, Molecular | |
11574465 EMBO J. 2001 PMC125277 Mice|Animals|perlecan|nidogen|*Heparan Sulfate Proteoglycans|*Membrane Glycoproteins|*Extracellular Matrix Proteins|Binding Site|Heparitin Sulfate|Basement Membrane|Fibronectins|Protein Binding|*Immunoglobulin-like Domain|Amino Acid Sequence|Heparin|Kinetics|Peptide Fragments | |
11574543 J. Biol. Chem. 2001 Humans|*bcl-2-Associated X Protein|*Apoptosis|TP53 protein, human|Tumor Suppressor Protein p53|CDKN1A protein, human|Cyclin-Dependent Kinase Inhibitor p21|Proto-Oncogene Proteins c-bcl-2|Caspases|Proto-Oncogene Proteins|Caspase 3|Cell Cycle|Signal Transduction|Mitochondria|Cyclins|DNA Damage|Tumor Cells, Cultured|Cytochrome c | |
11577081 J. Biol. Chem. 2001 Humans|CASP8 protein, human|*Caspase 8|*Tumor Necrosis Factor-alpha|HeLa Cells|*Apoptosis|Death Domain Receptor Signaling Adaptor Proteins|Caspases|*Isoforms|Nuclear Factor-Kappab|Alternative Splicing|Guanine Nucleotide Exchange Factors|Transfection | |
11577093 J. Biol. Chem. 2001 Animals|PRKDC protein, human|*DNA-Activated Protein Kinase|*DNA Breaks, Double-Stranded|*DNA Repair|Ku Autoantigen|Antigens, Nuclear|Nuclear Proteins|DNA Helicases|*G2 Phase|DNA-Binding Proteins|Recombination, Genetic|*DNA|DNA Damage|Radiosensitivity|*Genetic Testing|Protein Kinase | |
11577110 J. Biol. Chem. 2001 HIP1 protein, human|*DNA-Binding Proteins|*Binding Sites|Clathrin|epsin|Adaptor Proteins, Vesicular Transport|Clathrin-Coated Vesicles|Protein Binding|Endocytosis|amphiphysin|Nerve Tissue Proteins|Transcription Factors|Amino Acid Sequence|Carrier Proteins|Set2 protein, human|*Histone-Lysine N-Methyltransferase|Vesicular Transport Proteins | |
11577169 MP, Mol. Pathol. 2001 PMC1187084 *Calprotectin|*Zinc|Matrix Metalloproteinase 2|Matrix Metalloproteinase 9|Matrix Metalloproteinase 1|Matrix Metalloproteinase 3|Tissue Inhibitor of Metalloproteinase-1|Matrix Metalloproteinase 13|Matrix Metalloproteinase 8|Proteins | |
11578145 Toxicol. Appl. Pharmacol. 2001 Animals|Mice|*Selenomethionine|L-methionine gamma-lyase|Carbon-Sulfur Lyases|Cystathionine gamma-Lyase|Selenocysteine|Methionine|Selenium|*Antioxidants|Liver|propargylglycine|Glycine|Alkynes|Cytosol|*Esterases|*Endopeptidases|Methanol|*Dermatologic Agents | |
11579093 J. Biol. Chem. 2001 Humans|*Nuclear Pore|*RNA|nuclear pore protein p62|Nucleoporins|Nucleocytoplasmic Transport Proteins|Export, Nuclear|Karyopherins|RNA-Binding Proteins|Nuclear Proteins|mRNA|Cell Nucleus|ATP-Binding Cassette Transporters|HeLa Cells|Dimerization|Intron|Membrane Glycoproteins|NXT1 protein, human | |
11580899 Neuron 2001 Animals|Mice|SDC2 protein, human|*Syndecan-2|*Dendritic Spines|*Signal Transduction|EPHB2 protein, human|EphB2-Tyrosine Kinase|Dendrites|Neurons|Receptors, Eph|Hippocampus|Phosphorylation|Membrane Glycoproteins|Carrier Proteins|Proteoglycans|Morphogenesis|Cells, Cultured | |
11581164 Genes Dev. 2001 PMC312794 Mice|Animals|*p300-CBP Protein|estrogen receptor alpha, human|Estrogen Receptor alpha|*Estrogens|Nuclear Protein|Transcription Factors|Activation, Transcriptional|Receptors, Estrogen|Trans-Activators|ERbeta|Promoter Regions, Genetic|Protein Binding|Transcription, Genetic|Chromatin Immunoprecipitation|Binding Sites|CREB-Binding Protein|mRNA | |
11583147 Biochemistry 2001 Humans|*Adenosylmethionine Decarboxylase|*Substrate Specificity|Protein Conformation|Protein Binding|Binding Sites|Crystallography, X-Ray|Active Site|Models, Molecular|Putrescine|Kinetics|Static Electricity|Ligands|Amino Acids|Catalysis | |
11583593 Biochem. J. 2001 PMC1222165 Humans|*Sugar|Glucose Transporter|Amino Acid Sequence|Monosaccharide Transport Proteins|*Muscle, Skeletal|Exons|cDNA|Cloning, Molecular|*Facilitated Diffusion|Cytochalasin B|Transfection|RNA, Messenger|Biological Transport|Sequence Homology, Amino Acid | |
11583633 Mol. Cell 2001 Mice|Animals|Chromatin|transcription factor UBF|Pol1 Transcription Initiation Complex Proteins|rDNA|Transcription, Genetic|Promoter Regions, Genetic|Histones|CpG Islands|Chromatin Assembly and Disassembly|Transcription Factors|DNA Methylation|Epigenesis, Genetic|Nucleosomes|DNA-Binding Proteins|*Ribosomes|Gene Silencing|5 Azacytidine|Chromatin Immunoprecipitation | |
11583998 J. Biol. Chem. 2001 Humans|*Heat Shock Transcription Factor 1|*Transcription Factor|DNA-Binding Proteins|Stress Proteins|Transcription, Genetic|HSP90 Heat-Shock Proteins|Gene Expression Regulation|DNA|Heat-Shock Response | |
11584266 Nat. Cell Biol. 2001 Animals|*Septins|cdc42 GTP-Binding Protein|Protein Binding|Amino Acid Sequence|TYRP1 protein, human|*Membrane Glycoproteins|Protein Structure, Tertiary|Signal Transduction|Binding Sites|Sequence Homology, Amino Acid|Models, Molecular | |
11584272 Nat. Cell Biol. 2001 *Amyloid beta-Peptides|*Sterol O-Acyltransferase|*Acyl Coenzyme A|APP protein, human|*Amyloid beta-Protein Precursor|Amyloid Precursor Protein Secretases|Aspartic Acid Endopeptidases|Presenilin-1|Alzheimer Disease|Presenilin-2|Cholesterol|Enzyme Inhibitors | |
11585773 Cancer Res. 2001 Humans|CDK2 protein, human|*Cyclin-Dependent Kinase 2|*Phosphorylation|HeLa Cells|*Cell Cycle|CDC2-CDC28 Kinases|Cyclin-Dependent Kinases|Cyclins|Cyclin-Dependent Kinase Inhibitor p21|Cyclin E|Cyclin-Dependent Kinase Inhibitor p27|*Squamous Carcinomas|Cell Nucleus|Retinoblastoma Protein|G1 Phase|Microtubule-Associated Proteins|Carrier Proteins|*Colon | |
11585831 J. Biol. Chem. 2001 Humans|2-5A-dependent ribonuclease|Endoribonucleases|*mRNA Stability|Oligoribonucleotides|mitochondrial messenger RNA|RNA, Messenger|*Mitochondria|interferon-alpha 8|*Interferon-alpha|RNA, Mitochondrial|Adenine Nucleotides|Downregulation|Proteins|cDNA|Chaperonins|Gene Expression Regulation|Antiviral Agents|Apoptosis | |
11585840 J. Biol. Chem. 2001 NEDD8 protein, human|*NEDD8 Protein|Ubiquitins|Proteasome|Transcription Factors|Ubiquitin|Two-Hybrid System Techniques|Protein Binding|Downregulation|Proteolysis|Adaptor Proteins, Signal Transducing|Cysteine Endopeptidases|Cytoplasm | |
11585911 Mol. Cell. Biol. 2001 PMC99903 Animals|*Cryptochromes|*Drosophila|Drosophila melanogaster|*Light Signal Transduction|Drosophila Proteins|Photoreceptor Cells, Invertebrate|Period Circadian Proteins|Circadian Rhythms|Biological Clocks|Eye Proteins|Nuclear Proteins|Darkness|Light|Receptors, G-Protein-Coupled|Mutation|Cytoplasm|Signal Transduction|timeless protein, Drosophila | |
11585916 Mol. Cell. Biol. 2001 PMC99908 *Calmodulin|*Signal Transduction|Mitogen-Activated Protein Kinases|Calmodulin-Kinase|Mitogen-Activated Protein Kinase 3|ras Proteins|Proto-Oncogene Proteins c-raf|Mitogen-Activated Protein Kinase 1|Phosphatidylinositol 3-Kinases|Phosphorylation|Enzyme Activation|Isoforms|Protein Binding|Platelet-Derived Growth Factor|Cell Line | |
11585921 Mol. Cell. Biol. 2001 PMC99913 Animals|*Proteolysis|Notch Receptors|*Signal Transduction|FBXW7 protein, human|*F-Box-WD Repeat-Containing Protein 7|Caenorhabditis elegans Proteins|Receptor, Notch1|Cell Cycle Proteins|Caenorhabditis elegans|Transcription Factors|Membrane Proteins|Proteasome Endopeptidase Complex|Phosphorylation|Amino Acid Sequence|Ubiquitins|SEL-10 protein, C elegans | |
11585923 Mol. Cell. Biol. 2001 PMC99915 Animals|Chlorocebus aethiops|EPHB2 protein, human|*Receptor, EphB2|*Neurites|*Down-Regulation|*Mitogen-Activated Protein Kinases|*Receptor Protein-Tyrosine Kinases|*Ephrins|*Protein Binding|Phosphorylation|Signal Transduction|Ephrin-B1|MAP Kinase Signaling System|COS-1 Cells|Neurons|SH2 Domain|*Protein Transport|ras GTPase-Activating Proteins|ras Proteins | |
11585927 Mol. Cell. Biol. 2001 PMC99919 *Ribosomal Protein S6 Kinases, 90-kDa|Phosphorylation|MAPK3 protein, human|Mitogen-Activated Protein Kinase 3|Mitogen-Activated Protein Kinases|Signal Transduction|Enzyme Activations|Protein Binding|U 0126|Butadienes|Serine|Epidermal Growth Factor|Cell Line|Binding Sites|Cells, Cultured|Amino Acid Sequence|Nitriles | |
11586295 Nat. Genet. 2001 Humans|*Colorectal Neoplasms, Hereditary Nonpolyposis|MLH1 protein, human|MutL Protein Homolog 1|MutS Homolog 2 Protein|Mismatch Repair|Nuclear Proteins|DNA-Binding Proteins|Carrier Proteins|Germ-Line Mutation|Base Pair Mismatch|Adaptor Proteins, Signal Transducing|DNA Repair|Mutations, Missense|Mutation|Frameshift Mutation|Microsatellite Repeats|MLH3 protein, human|MutL Proteins | |
11588141 Endocr. Rev. 2001 *Acetylcholine|Insulin Secretion|Insulin|Islets of Langerhans|*Pancreatic beta Cell|Glucose|Exocytosis|Membrane Potentials|*Pancreas|Calcium|Sodium|Plasma Membrane|Muscarinic Receptors|Cholinergic Agents | |
11588157 Glycobiology 2001 Humans|*N-Acetyllactosamine Synthase|triaosylceramide 1,4-galactosyltransferase|*Galactosyltransferases|galactosylxylosylprotein 3-beta-galactosyltransferase|N-acetyllactosaminide alpha-1,3-galactosyltransferase|*Oligosaccharides|*Cell Line|cDNA|Lectins|Ricinus communis agglutinin-1|Plant Lectins|Transfections|Adenocarcinoma | |
11588175 J. Neurosci. 2001 PMC6763876 *Acid Sensing Ion Channels|*Nociceptors|*Anti-Inflammatory Agents, Non-Steroidal|Pain|*Inflammation|Ganglia, Spinal|Hyperalgesia|TRPV Cation Channels|Sensory Neurons|Aspirin|Patch-Clamp Techniques|Membrane Potentials | |
11588219 Science 2001 Animals|Chlorocebus aethiops|*beta-Arrestin|*Ubiquitination|*beta-Arrestin 1|MDM2 protein, human|Proto-Oncogene Proteins c-mdm2|*Signal Transduction|Ubiquitin|Arrestins|*Carrier Proteins|G Protein|E3 Ubiquitin Ligase|Receptors, Adrenergic, beta-2|Protein Transport|Transfections|Protein Binding|Kinetics|COS Cells | |
11590176 J. Biol. Chem. 2001 Humans|Rats|Animals|*Peroxisomes|*Intracellular Membranes|Amino Acid Sequence|Membrane Proteins|Green Fluorescent Proteins|Peroxisomal Targeting Signals|Protein Motifs | |
11590181 J. Biol. Chem. 2001 Animals|Chlorocebus aethiops|macrogolgin|*Integral Membrane Protein|*Golgi Matrix Proteins|Golgi Complex|Endoplasmic Reticulum|Yeast Two-Hybrid System|Carrier Proteins|Protein Binding|Protein Structure, Tertiary|Amino Acid Sequence|COS Cells|Cell Membrane|Sequence Homology, Amino Acid|mRNA|Blotting, Western|Protein Transport|Transfection|Subcellular Fractions | |
11590439 Nat. Med. 2001 Humans|*alpha-Synuclein|*Parkinson Disease|Lewy Bodies|*Ubiquitination|parkin protein|*Ubiquitin-Protein Ligases|Ubiquitin|Carrier Proteins|Inclusion Bodies|Cell Line|Transfection|Brain | |
11591141 Biochemistry 2001 Humans|*HIV-1|*HIV Envelope Protein gp120|CXCR4 protein, human|*Receptors, CXCR4|*HIV Antibodies|HIV Envelope Protein gp41|CD4 Antigens|Membrane Fusion|Cell Fusion|*HIV Seropositivity|HeLa Cells|Protein Conformation|Binding Sites|*Signal Transduction | |
11591158 Biochemistry 2001 Humans|Mice|Rats|Animals|*Cationic Amino Acid Transporters|Carrier Proteins|Biological Transport|Arginine|Xenopus laevis|Membrane Proteins|Plasma Membrane|Amino Acids|Oocytes|Active Transport | |
11591712 J. Biol. Chem. 2001 PMC1513547 Animals|*Active Transport, Cell Nucleus|*Period Circadian Proteins|Cytoplasm|Cell Nucleus|Nuclear Localization Signal|Nuclear Proteins|Transcription Factors|Cell Cycle Proteins|Circadian Rhythm|Phosphorylation|*Mammals|Amino Acid Sequence|Cell Line | |
11594753 Biochem. Biophys. Res. Commun. 2001 Humans|NAD kinase|*Phosphotransferases (Alcohol Group Acceptor)|Cloning, Molecular|NAADP|NADP|cDNA|Amino Acid Sequence|Escherichia coli|cDNA Library|Nucleotides|Kinetics|Sequence Homology, Amino Acid | |
11595180 Cell 2001 *B-DNA|DNA Polymerases|DNA Repair|DNA Replication|Protein Conformation|DNA Polymerase beta|DNA Damage|DNA|Protein Structure, Tertiary|Amino Acid Sequence|Models, Molecular|Crystallography, X-Ray|Protein Binding|Catalytic Domain | |
11595726 Clin. Cancer Res. 2001 CDK4 protein, human|*Cyclin-Dependent Kinase 4|*Cyclin-Dependent Kinase Inhibitor p16|Melanoma, Cutaneous Malignant|*Melanoma|Skin Neoplasms|Cyclin-Dependent Kinase 6|Mutations|Proto-Oncogene Proteins|Mutations, Germline|Cell Cycle|*Cyclin-Dependent Kinase Inhibitor Proteins|Carrier Proteins|Protein Binding|Protein Kinase Inhibitors | |
11595941 Nature 2001 Humans|Female|Male|Mice|Animals|*Sperm Motility|*Sperm|Sperm Tail|Calcium Channels|Fertilization|Cyclic AMP|Amino Acid Sequence|Contraceptives|Fertility | |
11598006 EMBO J. 2001 PMC125676 TOM translocase|*Cytochromes c|*Mitochondrial Membranes|Saccharomyces cerevisiae Proteins|Mitochondrial Membrane Transport Proteins|Mitochondria|Saccharomyces cerevisiae|Neurospora crassa|Membrane Proteins|Ion Channels|Protein Precursors|cytochrome C synthetase|Lyases|Apoprotein | |
11598010 EMBO J. 2001 PMC125681 Humans|*Phosphatidylinositol 3-Kinase|EPO protein, human|*Erythropoietin|2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one|Chromones|Erythropoietin Receptor|Signal Transduction|Phosphorylation|*Epoetin Alfa|Phosphatidylinositol 3-Kinases|*Cell Differentiation|Proto-Oncogene Proteins c-akt|Morpholines|*Protein Binding|Proto-Oncogene Proteins|Phosphoinositide-3 Kinase Inhibitors|src-Family Kinases|Enzyme Activation | |
11598127 J. Biol. Chem. 2001 Animals|Humans|*Anaphase Promoting Complex|*Phosphatase, Dual-Specificity|*Anaphase|HeLa Cells|Cyclin B|Cell Cycle Proteins|Mitosis|Cyclins|Cdc20 Proteins|Cdh1 Proteins|Ubiquitin-Protein Ligases|CDC2 Protein Kinase|Phosphorylation|Saccharomyces cerevisiae Proteins|pituitary tumor-transforming protein 1, human|Securin|CDH1 protein, human|Cadherins | |
11598268 Science 2001 Animals|*Prolyl 4-Hydroxylase|Drosophila melanogaster|*Procollagen-Proline Dioxygenase|Transcription Factors|DNA-Binding Proteins|Nuclear Proteins|Amino Acid Sequence|*Oxidation-Reduction|Cell Line|Cell Hypoxia|Oxygen|Cytoplasm|Proline|RNA, Messenger | |
11598301 Science 2001 AKT1 protein, human|*Proto-Oncogene Proteins c-akt|Phosphorylation|Signal Transduction|*Plasma Membrane|Proto-Oncogene Proteins|TYRP1 protein, human|*Membrane Glycoproteins|Threonine|Serine|Enzyme Activation|Protein Processing, Post-Translational|Insulin|Transfection|Cell Line | |
11600407 Am. J. Physiol., Cell Physiol. 2001 *Vascular Endothelial Growth Factor A|Endothelial Cells|*Vascular Endothelial Growth Factors|*Phospholipase C gamma|*Fibroblast Growth Factor|*Cell Proliferation|Signal Transduction|Mitogen-Activated Protein Kinases|Receptors, Vascular Endothelial Growth Factor|Protein Kinase C|Phosphorylation|1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione|Estrenes|Endothelium, Vascular|*Choroids|Pyrrolidinones | |
11600536 J. Clin. Endocrinol. Metab. 2001 Rats|Animals|Humans|*Ghrelin|*Stomach|Fasting|Anorexia Nervosa|Insulin-Like Growth Factor I|Body Mass Index|*Upper Gastrointestinal Tract | |
11601986 Biochemistry 2001 *Protein Kinase A|*Phosphorylation|*Calcium|*Signal Transduction|*G Protein|Transducin|Rod Cell Outer Segment|RGS Proteins|Rhodopsin|Photoreceptors, Vertebrate|G-Protein beta Subunit|GTP Phosphohydrolases|Kinetics|Protein Kinase C|Amino Acid Sequence | |
11601988 Biochemistry 2001 Humans|APEX1 protein, human|*DNA-(Apurinic or Apyrimidinic Site) Lyase|*Flap Endonucleases|*Proliferating Cell Nuclear Antigen|*Base Excision Repair|Pol beta protein, human|DNA Polymerase beta|Deoxyribonuclease IV (Phage T4-Induced)|DNA Ligases|DNA Ligase ATP|Endodeoxyribonucleases|Carbon-Oxygen Lyases|DNA-Binding Proteins|Base Sequence | |
11602640 J. Exp. Med. 2001 PMC2193511 Humans|Mice|Animals|*Receptors, CCR7|TREM2 protein, human|Membrane Glycoproteins|Receptors, Immunologic|Monocyte|Signal Transduction|B7-2 Antigen|Dendritic Cells|Nuclear Factor-Kappab|Mitogen-Activated Protein Kinase 3|Extracellular Signal Regulated Kinases|Mitogen-Activated Protein Kinase 1|Protein-Tyrosine Kinases|Receptors, Cell Surface|Toll-Like Receptor|Adaptor Proteins, Signal Transducing|Phosphorylation|Myeloid Cells | |
11602804 Glycoconj. J. 2001 Cricetinae|Humans|Animals|Mice|*Cytidine Monophosphate N-Acetylneuraminic Acid|*Sialic Acid|Cricetulus|CMP-deaminoneuraminic acid|Neuraminic Acids|N-Acylneuraminate Cytidylyltransferase|cytidine monophosphate-N-glycoloylneuraminic acid|cytidine-5'-monophosphosialic acid|Sialic Acids|Cytidine Monophosphate|N-acetylmannosamine|Hexosamines|N-acetylneuraminate synthase|Oxo-Acid-Lyases|Baculovirus|Glycoproteins|*Insect|Cloning, Molecular | |
11604075 Radiat. Res. 2001 *Ionizing Radiation|*DNA Damage|Monte Carlo Method|Linear Energy Transfer|DNA|Protons|Alpha Particles|Electrons|Computer Simulation | |
11604131 Neuron 2001 Animals|*rho GTPases|plexin|*Nerve Tissue Proteins|*Cell Adhesion Molecules|Semaphorin|*Signal Transduction|RHOA protein, human|rhoA GTP-Binding Protein|Receptors, Cell Surface|Membrane Proteins|Drosophila Proteins|Drosophila|Axons|Carrier Proteins | |
11604140 Neuron 2001 *Synapse|phosphoinositide 5-phosphatase|Phosphoric Monoester Hydrolases|synaptojanin|Clathrin|Synaptic Vesicles|Nerve Tissue Proteins|Endocytosis|Synaptic Transmission|1-Phosphatidylinositol 4-Kinase|Nerve Endings|Phosphotransferases (Alcohol Group Acceptor)|Phosphorylation|Actin | |
11604393 J. Biol. Chem. 2001 Rats|Animals|*Actins|Guanylate Kinases|*Cytoskeletal Proteins|Cell Surface Proteins|Nucleoside-Phosphate Kinase|Adaptor Proteins, Signal Transducing|Nerve Tissue Proteins|Protein Isoforms|Protein Binding|Calcium-Calmodulin-Dependent Protein Kinases|Cell Membrane|*Phosphoproteins|Transcription Factors|Spectrin|Glycophorin C|Neurons | |
11604418 J. Cell Biol. 2001 PMC2198845 Dynamin|amphiphysin|Nerve Tissue Proteins|Clathrin|Synaptic Vesicles|Carrier Proteins|Synapse|src Homology Domains|Adaptor Proteins, Signal Transducing|Endocytosis|2-acylglycerophosphate acyltransferase|Acyltransferases|GTP Phosphohydrolases|Amino Acid Sequence|Protein Binding|polyphosphoinositide phosphatase|Phosphoric Monoester Hydrolases | |
11604492 Mol. Cell. Biol. 2001 PMC99927 Humans|Mice|Animals|NR1H3 protein, human|*Liver X Receptors|ABCA1 protein, human|ATP Binding Cassette Transporter 1|Orphan Nuclear Receptors|*Promoter Regions, Genetic|ATP Binding Cassette Transporter, Subfamily G, Member 1|Receptors, Retinoic Acid|oxidized low density lipoprotein|Lipoproteins, LDL|Macrophages|Cholesterol|Gene Expression Regulation|Apo E|Macrophages, Peritoneal|ATP-Binding Cassette Transporters|Sterol Regulatory Element Binding Protein 1|Response Elements | |
11604500 Mol. Cell. Biol. 2001 PMC99935 *Focal Adhesion Kinase|*Phosphorylation|PTK2 protein, human|*Focal Adhesion Kinase 1|BCAR1 protein, human|Crk-Associated Substrate|src Tyrosine Kinases|src Homology Domains|Signal Transduction|Oncogene Protein pp60(v-src)|Retinoblastoma-Like Protein p130|Binding Sites|Integrins|Cell Adhesion|Tyrosine|Oncoproteins | |
11606061 Biochem. Biophys. Res. Commun. 2001 Mice|Animals|IGFBP5 protein, human|*Insulin-Like Growth Factor Binding Protein 5|IGF1 protein, human|IGF-1|*Cell Differentiation|IGFBP|Insulin-Like Growth Factor Binding Protein 4|mRNA|Transfections|Media, Conditioned|Cell Division|Cells, Cultured|Osteosarcoma | |
11606067 Biochem. Biophys. Res. Commun. 2001 *PI-3 Kinase|*Phosphorylation|GRB2 protein, human|*GRB2 Adaptor Protein|*Phosphatidylinositol 3-Kinase|src Homology Domain|Phosphoproteins|MET protein, human|Hepatocyte Growth Factor Receptor|Epidermal Growth Factor|HGF protein, human|Hepatocyte Growth Factor|Signal Transduction|ErbB Receptors|Amino Acid Sequence|Enzyme Activation|Binding Sites|Tyrosine | |
11606068 Biochem. Biophys. Res. Commun. 2001 Humans|*Retinoids|*Oxysterols|ABCG1 protein, human|ATP Binding Cassette Transporter, Subfamily G, Member 1|ABCA1 protein, human|ABCA1 Protein|Exons|*Monocyte-Derived Macrophages|Transporters, ABC|Introns|Amino Acid Sequence|DNA, Complementary|Cloning, Molecular|Cholesterol|RNA, Messenger|Receptors, Nuclear|Sequence Homology, Protein|Promoter Regions, Genetic | |
11606574 J. Biol. Chem. 2001 Humans|*Carbonic Anhydrase II|*Exchangers, Chloride-Bicarbonate|*Bicarbonates|HEK293 Cells|Anion Exchange Protein 1, Erythrocyte|Carbonic Anhydrase|Plasma Membrane|Protein Binding|Ion Transport|Acetazolamide|Binding Site|Chlorides|Cytoplasm|Active Transport | |
11606584 J. Biol. Chem. 2001 Humans|*Phospholipase C gamma 2|*Tyrosine|Receptors, Antigen, B-Cell|*B-Lymphocytes|*Signal Transduction|Tyrosine Kinase|Phosphorylation|Syk Kinase|src Homology Domains|Enzyme Activation|Intracellular Signaling Peptides and Proteins|Enzyme Precursors|Agammaglobulinaemia Tyrosine Kinase|Calcium|Isoenzymes|Adaptor Proteins, Signal Transducing|Cell Line | |
11607023 Nature 2001 *Small Nuclear RNA|*RNA Splicing|Spliceosomes|Sequences, Intervening|RNA Precursors|RNA, Catalytic|*Catalysis|Base Sequence|Nucleic Acid Conformation|Catalytic Domain | |
11607032 Nature 2001 Mice|Animals|TLR3 protein, human|*Toll-Like Receptor 3|*NF-kappa B|*RNA, Double-Stranded|Toll-Like Receptors|Receptors, Immunologic|Signal Transduction|Myeloid Differentiation Factor 88|RELA protein, human|*Transcription Factor RelA|Adaptor Proteins, Signal Transducing|Receptors, Interleukin-1|Toll-Like Receptor 4|Mitogen-Activated Protein Kinases|Membrane Glycoproteins|Antigens, Differentiation|Cytokines|Poly I-C | |
11607830 Oncogene 2001 Humans|Mice|Animals|SLP-76 signal Transducing adaptor proteins|Phosphoproteins|*Cell Signaling|T Cell Receptor|Lymphocyte Activation|SH3 Domain|Carrier Proteins|Membrane Proteins|GRB2 protein, human|GRB2 Adaptor Protein|PLC gamma1|Tec protein-tyrosine kinase|Tyrosine Kinase|Phosphorylation|Jurkat Cells|Caspases|Hematopoietic Stem Cell Transplantation | |
11607834 Oncogene 2001 Animals|GRB7 protein, human|*GRB7 Protein|*Protein Binding|*Signal Transduction|GRB10 protein, human|GRB10 Adaptor Protein|SH2 Domain|Phosphorylation|GRB14 protein, human|Adaptor Proteins, Signal Transducing|Cell Migration|Tyrosine|Caenorhabditis elegans | |
11668611 Hum. Mutat. 2001 Animals|Humans|*Mucopolysaccharidosis III|alpha-N-acetyl-D-glucosaminidase|Acetylglucosaminidase|N-sulfoglucosamine sulfohydrolase|Hydrolases|DNA Mutational Analysis|Mutations|Phenotype|heparan sulfate sulfatase|Sulfatases|Mutations, Missense | |
11672424 Biochem. J. 2001 PMC1222171 Rats|Humans|Animals|*Prostaglandin D2|prostaglandin R2 D-isomerase|*Intramolecular Oxidoreductases|*Lipocalins|Amino Acid Sequence|*Catalysis|Recombinant Proteins|Glutathione Transferase|Sequence Alignment|Sequence Homology, Amino Acid|Complementary DNA|Models, Molecular|Glutathione|Oxidation-Reduction|Binding Site|Escherichia coli | |
11672446 Biochem. J. 2001 PMC1222193 Animals|Humans|*Diacylglycerol O-Acyltransferase|*CoA, Acyl|Acyltransferases|1,2-diacylglycerol|Diglycerides|Triglycerides|Amino Acid Sequence|cDNA|Lipogenesis|Transfections|disuccinimidyl suberate|Succinimides | |
11672528 Cell 2001 Nerve Tissue Proteins|Receptors, Immunologic|rho GTPase-activating protein|*GTPase-Activating Proteins|*Signal Transduction|*Cell Movement|*Neurogenesis|cdc42 GTP-Binding Protein|Drosophila Proteins|Neurons|Cells, Cultured | |
11672531 Cell 2001 Mice|Animals|*C EBPalpha|*Adipogenesis|Transcription Factor|DNA-Binding Proteins|Cell Differentiation|Gene Expression Regulation|E2F Transcription Factors|Nuclear Proteins|Adipocytes|Granulocytes|*Leukopoiesis|Promoter Regions, Genetic|Protein Binding|*Hematopoiesis|Cellular Proliferation|Cell Line|Cell Cycle | |
11673449 J. Biol. Chem. 2001 H2AX protein, human|*Histones|*Phosphorylation|*DNA Replication|DNA Breaks, Double-Stranded|DNA Repair|Ataxia Telangiectasia Mutated Proteins|DNA Damage|Cell Cycle Proteins|Proliferating Cell Nuclear Antigen|DNA-Binding Proteins|Ultraviolet Rays|BRCA1 protein, human|BRCA1 Protein|Ionizing Radiation | |
11673457 J. Biol. Chem. 2001 Mice|Animals|*Lipid Metabolism|3-hydroxy-3-methylglutaryl-coenzyme A|CoA, Long-Chain Acyl|Peroxisomes|pristanic acid|Acids, Fatty|Thiolester Hydrolases|Coenzyme A|Peroxisome Proliferators|Amino Acid Sequence|Peroxisome Proliferator-Activated Receptor alpha|Cloning, Molecular|Mitochondria|Sequence Alignment|Oxidation-Reduction|Kinetics|pirinixic acid|Pyrimidines | |
11675392 J. Biol. Chem. 2001 Rab geranylgeranyltransferase|*Alkyl and Aryl Transferases|geranylgeranyl pyrophosphate|Polyisoprenyl Phosphates|Protein Prenylation|Kinetics|Protein Binding|Substrate Specificity|rab GTP-Binding Proteins|Adaptor Proteins, Signal Transducing|Spectrometry, Fluorescence | |
11676494 Biochem. Biophys. Res. Commun. 2001 Animals|Humans|CA9 protein, human|*Carbonic Anhydrase IX|Oxygen-18|*Oxygen Isotopes|Carbonic Anhydrases|Antigens, Neoplasm|Carbonic Anhydrase I|Carbonic Anhydrase II|*Catalysis|Neoplasm Proteins|Sulfonamides|Integral Membrane Protein|Structure-Activity Relationship|Hydrogen-Ion Concentration|Kinetics|Cytosol|Proton | |
11676921 Curr. Biol. 2001 Animals|*Substrate Specificity|*Inositol|Saccharomyces cerevisiae|myo-inositol-1 (or 4)-monophosphatase|phosphatidylinositol 5-phosphate|Phosphatidylinositol Phosphates|myotubularin|Protein Tyrosine Phosphatases, Non-Receptor|phosphatidylinositol 3-phosphate|Myotubular Myopathy, X-Linked|Protein Tyrosine Phosphatases|PTEN protein, human|PTEN Phosphohydrolase|Phosphatidylinositols|Protein Transport|Proteins|Mutations|Vacuoles | |
11677247 J. Biol. Chem. 2001 Humans|*Aspartate-Ammonia Ligase|CEBPB protein, human|*CCAAT-Enhancer-Binding Protein-beta|Gene Activation|Response Element|Promoter Regions, Genetic|Transcription, Genetic|Transfection|Cell Nucleus|Amino Acids|RNA, Messenger|Gene Expression Regulation, Enzymologic|Hepatoma|Liver Neoplasms|Nutrient | |
11678376 J. Chromatogr. B Biomed. Sci. Appl. 2001 Humans|abacavir|*Chromatography, High Performance Liquid|*Dideoxynucleosides|reverse transcriptase, Human immunodeficiency virus 1|HIV Reverse Transcriptase|Reverse Transcriptase Inhibitors|HIV-1|Anti-HIV Agents|Spectrophotometry, Ultraviolet|HIV Infections|*Biological Assay | |
11679424 Diabetes 2001 Mice|Animals|HNF1A protein, human|*Hepatocyte Nuclear Factor 1-alpha|Pancreatic Islet|pancreatic and duodenal homeobox 1 protein|Trans-Activators|Insulin|Nuclear Proteins|Insulin Secretion|Hepatocyte Nuclear Factor 1|Hepatocyte Nuclear Factor 1-beta|Homeodomain Proteins|Gene Expression Regulation|Diabetes Mellitus, Type 2|Glucose|Promoter Regions, Genetic|mRNA|Mutations | |
11679632 Science 2001 *Amyloid Precursor Protein Secretases|*Receptor, ErbB-4|*Tyrosine Kinase|Aspartic Acid Endopeptidases|Presenilin-1|*Receptor Protein-Tyrosine Kinases|Signal Transduction|Cell Membrane|*Cell Nucleus|Amino Acid Sequence|Protein Structure, Tertiary|Cell Line|Protein Binding|Phorbol 13-Acetate, 12-O-Tetradecanoyl|Metalloproteases|Transfection | |
11679716 Acta Crystallogr. D Biol. Crystallogr. 2001 Humans|*Aldolase|*Fructose|Fructose Intolerance, Hereditary|Protein Conformation|*Aldehyde-Lyases|X Ray Crystallographies|Amino Acid Sequence|Protein Structure, Secondary|Models, Molecular|*Liver|Kinetics|Isoenzymes|Active Site|Mutations|Point Mutations | |
11681785 Mol. Membr. Biol. 2001 Humans|Animals|*Glucose Transport Facilitators|*Glucose Transporter Type 1|Monosaccharide Transport Proteins|Protein Structure, Secondary|Amino Acid Sequence|Glucose|Mutagenesis, Site-Directed|Biological Transport|Xenopus laevis|Kinetics|Cell Membrane|Models, Molecular|Cysteine|Biophysics | |
11682468 J. Biol. Chem. 2001 Cricetinae|Animals|*Sterol Esterase|CHO Cells|Cricetulus|FABP4 protein, human|*Adipocyte Lipid Binding Protein|Mutagenesis, Site-Directed|Transfection|Protein Binding|Acids, Fatty|Recombinant Fusion Proteins|Hydrolysis|Oleate|Adipocytes | |
11682626 Mol. Endocrinol. 2001 Humans|estrogen receptor alpha, human|*Estrogen Receptor alpha|*Furylfuramide|*alpha-Helical Structure|NCOA1 protein, human|*Steroid Receptor Coactivator 1|Estrogen Receptor beta|afimoxifene|Tamoxifen|Receptors, Estrogen|G-T mismatch-binding protein|DNA-Binding Proteins|Estrogen Antagonists|Histone Acetyltransferases|Trans-Activators|Estradiol|Transcriptional Activation|Binding Sites | |
11683476 Blood Press Suppl 2001 Humans|tasosartan|Tetrazoles|candesartan|losartan carboxylic acid|Losartan|Angiotensin Receptor Antagonists|Antihypertensive Agents|Benzimidazoles|Valsartan|Receptor, Angiotensin, Type 1|Angiotensin II|Receptor, Angiotensin, Type 2|Irbesartan|Hypertension|eprosartan|Imidazoles|Blood Pressure|Biphenyl Compounds | |
11684014 Mol. Cell 2001 Humans|*Tumor Suppressor Protein p53|TP53BP2 protein, human|Apoptosis Regulatory Proteins|bcl-2-Associated X Protein|Proto-Oncogene Proteins c-bcl-2|Cyclin-Dependent Kinase Inhibitor p21|Apoptosis|Proto-Oncogene Proteins|Cyclins|Cell Cycle|Promoter Regions, Genetic|TYRP1 protein, human|*Membrane Glycoproteins|Transcriptional Activation|Intracellular Signaling Peptides and Proteins|Gene Expression Regulation, Neoplastic|Tumor Cells, Cultured|Binding Sites | |
11684017 Mol. Cell 2001 CDK2 protein, human|*Cyclin-Dependent Kinase 2|Cyclins|CDC2-CDC28 Kinases|Cyclin-Dependent Kinase 4|Cyclin-Dependent Kinase Inhibitor p21|Cell Cycle|Cyclin-Dependent Kinase 6|Cyclin E|*Cell Proliferation|Cyclin-Dependent Kinase Inhibitor p27|Proto-Oncogene Proteins|Transcription Factor|Phosphorylation|CCAAT-Enhancer-Binding Protein-alpha|Cyclin-Dependent Kinase Inhibitor p16|Microtubule-Associated Proteins | |
11684289 Mol. Immunol. 2001 *MHC Class II Molecules|Antigen Presentation|*Antigens|Antigen Presenting Cells|Endocytosis|T Cells|Peptides|Plasma Membrane | |
11687589 J. Biol. Chem. 2001 Animals|*Flap Endonucleases|*S Phase|*DNA Repair|Proliferating Cell Nuclear Antigen|DNA Damage|DNA Breaks, Double-Stranded|Endodeoxyribonucleases|Methylmethane Sulfonate|Comet Assay|Endonucleases|Protein Binding|UV Light | |
11687658 Proc. Natl. Acad. Sci. U.S.A. 2001 PMC60805 Humans|p21(ras) farnesyl-protein transferase|*Farnesyltransferase|farnesyl pyrophosphate|Polyisoprenyl Phosphates|*Farnesyl-Diphosphate Farnesyltransferase|Protein Prenylation|Protein Conformation|Amino Acid Sequence|Substrate Specificity|L 739750|Oligopeptides|Binding Sites|Sesquiterpenes|Peptides|Kinetics|Models, Molecular|Proteins|Mutagenesis, Site-Directed | |
11687798 Nat. Genet. 2001 Pregnancy|Humans|Female|*Bartter Syndrome|*Hearing Loss, Sensorineural|*Mutation|Chloride Channels|Pedigree|Phenotype|*Failure, Kidney|BSND protein, human | |
11688984 Biochem. Biophys. Res. Commun. 2001 Humans|*Lymphocyte Activation|CD163 antigen|Antigens, Differentiation, Myelomonocytic|Antigens, CD|Receptors, Cell Surface|Monocytes|Macrophages|Scavenger Receptor|IL10 protein, human|IL10|*Phorbol Esters|Inflammation|Glucocorticoids|Upregulation|Cell Proliferation|Lymphocytes | |
11689006 Biochem. Biophys. Res. Commun. 2001 CTTN protein, human|*Cortactin|*Actins|*Caspases|*Protein Binding|*Apoptosis|CASP3 protein, human|Caspase 3|src Homology Domain|Carrier Proteins|Binding Sites|Amino Acid Sequence|Cell Signaling|Transfection|*Synapsins|*Hematopoietic System | |
11689432 EMBO J. 2001 PMC125712 ANGPT1 protein, human|*Angiopoietin-1|Phosphorylation|Signal Transduction|*Cell Migration|Adaptor Proteins, Signal Transducing|Phosphoproteins|PAK1 protein, human|PAK Kinases|TEK protein, human|Tek Receptor|Oncogene Proteins|Receptor Protein-Tyrosine Kinases|Phosphotyrosine|Binding Site|Protein-Tyrosine Kinases|Protein Binding|Cell Membrane | |
11689439 EMBO J. 2001 PMC125711 *SNAREs|*Membrane Fusion|Golgi Apparatus|Saccharomyces cerevisiae|Saccharomyces cerevisiae Proteins|Vesicular Transport Proteins|*Protein Binding|Intracellular Membranes|rab GTPases|Qa-SNARE Proteins|Protein Transport|Endosome|*Membranes|Guanine Nucleotide Exchange Factors | |
11689445 EMBO J. 2001 PMC125704 Humans|Mice|Animals|*PI3-Kinase|*Oestradiol|*MCF-7 Cells|*Phosphatidylinositol 3-Kinase|*Estrogens|estrogen receptor alpha, human|ERalpha|Signal Transduction|PIK3CG protein, human|*Class Ib Phosphatidylinositol 3-Kinase|Proto-Oncogene Proteins c-akt|Phosphorylation|CCND1 protein, human|Cyclin D1|Receptors, Estrogen|src-Family Kinases|Enzyme Activation|Proto-Oncogene Proteins | |
11689559 J. Biol. Chem. 2001 phorbol ester receptor|*Protein Kinase C Receptors|*Phorbol Esters|Protein Kinase C|Receptors, Drug|beta-chimaerin|Neoplasm Proteins|Signal Transduction|Isozymes|rac GTP-Binding Proteins|GTPase-Activating Proteins|Protein Binding|1,2-diacylglycerol|Diglycerides|Proteins, Chimaerin|Amino Acid Sequence|*Protein Domains | |
11689689 Mol. Cell. Biol. 2001 PMC99965 *eIF-2 Kinase|*Haem|Eukaryotic Initiation Factor-2|*Cells, Erythroid|Reticulocytes|Phosphorylation|Protein Biosynthesis|Oxidative Stress|*Cytoplasm|HSP90 Heat-Shock Proteins|Reactive Oxygen Species|HSP70 Heat-Shock Proteins|arsenite|Arsenites | |
11689693 Mol. Cell. Biol. 2001 PMC99969 Animals|Chlorocebus aethiops|*Microtubule|KTN1 protein, human|*Membrane Proteins|RHOA protein, human|rhoA GTP-Binding Protein|Kinesin|cdc42 GTP-Binding Protein|Cytoskeleton|rac1 GTP-Binding Protein|Transcription Factors|Signal Transduction|Guanosine Triphosphate|Actins|Endoplasmic Reticulum|COS-7 Cells|Protein Binding | |
11689702 Mol. Cell. Biol. 2001 PMC99978 Mice|Animals|FGFR1 protein, human|*Receptor, Fibroblast Growth Factor, Type 1|*Phosphatidylinositol 3-Kinase|*Proto-Oncogene Proteins c-akt|*Cell Survival|*Myeloproliferative Disorder|*Mitogen-Activated Protein Kinases|*Translocation, Genetic|MTOR protein, human|*TOR Serine-Threonine Kinases|Oncogene Proteins, Fusion|Phosphorylation|Signal Transduction|*Cell Proliferation|STAT3 protein, human|STAT3 Transcription Factor|STAT5A protein, human|STAT5 Transcription Factor | |
11690631 Biochim. Biophys. Acta 2001 Chlorocebus aethiops|Mice|Humans|Animals|*5'-Nucleotidase|nucleotidase|*Nucleotidases|*Cytosol|Amino Acid Sequence|Adenosine|Cloning, Molecular|cni protein, Drosophila|Drosophila Proteins|Substrate Specificity|Kinetics|Sequence Homology, Amino Acid|Heart|Membrane Proteins|COS-7 Cells|*Infertility | |
11691915 Nucleic Acids Res. 2001 PMC60197 Humans|Male|Mice|Animals|*Transcriptional Activation|CTNNB1 protein, human|beta Catenin|DNA-Binding Proteins|*Signal Transduction|High Mobility Group Proteins|TCF Transcription Factors|Trans-Activators|Wnt Proteins|Transcription, Genetic|Proto-Oncogene Proteins|Lymphoid Enhancer-Binding Factor 1|Zebrafish Proteins|mRNA|Amino Acid Sequence|SOXF Transcription Factors|Protein Binding|SOX7 protein, human | |
11691921 Nucleic Acids Res. 2001 PMC60176 Animals|*Open Reading Frames|*5' Untranslated Regions|Ribosomes|Codon, Initiator|Protein Biosynthesis|Peptide Chain Initiation, Translational|Transcription Factors|Gene Expression Regulation|DDIT3 protein, human|*Transcription Factor CHOP|RNA, Messenger|Base Sequence|Nuclear Protein | |
11693189 Mol. Cell. Biochem. 2001 Humans|Swine|Animals|*Calcitonin Receptor-Like Protein|*Receptor Activity Modifying Proteins|Iodine-125|*Iodine Radioisotopes|*HEK293 Cells|Receptor Activity-Modifying Protein 3|Receptor Activity-Modifying Protein 2|Receptor Activity-Modifying Protein 1|Receptor, Adrenomedullin|Receptors, Calcitonin|Adrenomedullin|Intracellular Signaling Peptides and Proteins|Membrane Proteins|Calcitonin Gene-Related Peptide|GPR182 protein, human|Receptors, G-Protein-Coupled|Calcitonin|Transfection | |
11694501 J. Biol. Chem. 2001 Mice|Animals|JAK2 protein, human|*Janus Kinase 2|PTPN1 protein, human|*Protein Tyrosine Phosphatase 1B|JAK1 protein, human|Janus Kinase 1|Phosphorylation|Signal Transduction|INSR protein, human|Insulin Receptor|Substrate Specificity|Intracellular Signaling Peptides and Proteins|Antigens, CD | |
11694537 J. Biol. Chem. 2001 complement factor H, human|*Complement Factor H|*Complement C3 Convertase, Alternative Pathway|*CD55 Antigens|*C3 Convertase|*Receptors, Complement 3b|Complement C3b Inactivator Proteins|Factor B|Complement Activating Enzymes|Complement C3b|Receptors, Complement|Complement Activation | |
11694590 Mol. Biol. Cell 2001 PMC60277 Animals|*Clathrin|*Transcription Factor AP-1|Golgi Apparatus|Protein Binding|trans Golgi Network|gamma-Adaptin|ADP-Ribosylation Factors|Adaptor Proteins, Vesicular Transport|Carrier Proteins|Saccharomyces cerevisiae|Protein Structure, Tertiary|Amino Acid Sequence|Endosomes|Membrane Proteins|Biological Transport|Sequence Homology, Amino Acid | |
11694877 Nat. Genet. 2001 Animals|Mice|*Neural Crest|Transcription Factors|Transactivator|*Heart Defects, Congenital|*Exencephaly|AP-2, Transcription Factor|Repressor Proteins|EP300 protein, human|E1A-Associated p300 Protein|Mutations|Isoforms|Cited2 protein, mouse | |
11695836 J. Bioenerg. Biomembr. 2001 Female|Pregnancy|Humans|*NAD|*Ubiquinone|*Electron Transport Complex I|Disorders, Mitochondrial|*Metabolism, Inborn Errors|DNA, Mitochondrial|Mitochondria|DNA Mutational Analysis|NADH, NADPH Oxidoreductases|Cell Nucleus|Mutations|Proteins|Fibroblast | |
11695992 Biochem. J. 2001 PMC1222202 Mice|Animals|PXN protein, human|*Paxillin|*Phosphorylation|*Binding Sites|Protein Binding|Focal Adhesion Kinase 1|Phosphotyrosine|Focal Adhesion Protein-Tyrosine Kinases|Cytoskeletal Proteins|src Homology Domain|Proto-Oncogene Proteins c-crk|Focal Adhesion|Transductions, Signal|Cell Adhesion|Tyrosine|Amino Acid Sequence|Genes, abl|3T3 Cells | |
11696000 Biochem. J. 2001 PMC1222210 Humans|Mice|Animals|*Adiposity|*Obesity|*Thermogenesis|Adipose Tissue, Brown|Cloning, Molecular|Amino Acid Sequence|Palmitoyl-CoA Hydrolase|Base Sequence|Sequence Alignment|DNA, Complementary|Open Reading Frame|Sequence Homology, Amino Acid|mRNA|Diet | |
11696015 Biochem. J. 2001 PMC1222225 Humans|*Focal Adhesion Protein-Tyrosine Kinases|*Phosphorylation|*Vascular Endothelial Growth Factor A|*Tyrosine|*Endothelial Cells|PTK2 protein, human|*Focal Adhesion Kinase 1|*Vascular Endothelial Growth Factors|Paxillin|Signal Transduction|Cell Migration|src-Family Kinases|Focal Adhesion|Cell Adhesion|Cytoskeletal Proteins|Endothelium, Vascular|PtdIns 3-Kinase | |
11696542 J. Biol. Chem. 2001 Cattle|Animals|*Thrombin|*Factor XI|adhesion receptor|Glycoprotein Ib alpha|glycocalicin|Platelets|Platelet Activation|*Complement Factor B|von Willebrand Factor|kininogen 1, human|Kininogens|Binding Site|3'-(1-butylphosphoryl)adenosine|Protein Binding|Cell Membrane|Blood Coagulation|High Molecular Weight Kininogen | |
11697121 Free Radic. Res. 2001 3-nitrotyrosine|*Tyrosine|Nitrites|Nitrates|Reactive Nitrogen Species|Nitric Oxide|*Diet|Peroxynitrite|Superoxide|Hydrogen Peroxide | |
11697890 Exp. Cell Res. 2001 Animals|14-3-3 Proteins|bcl-Associated Death Protein|*Isoforms|Proto-Oncogene Proteins|Apoptosis|Caspases|Proto-Oncogene Proteins c-akt|Phosphorylation|Phosphatidylinositol 3-Kinases|Carrier Proteins|Signal Transduction|Proto-Oncogene Proteins c-raf|*Cell Death|Ligands|Transfection|Cell Division|Blotting, Western | |
11698112 Biochimie 2001 Animals|Swine|BGN protein, human|Biglycan|*Collagen|Aggrecan|Decorin|Extracellular Matrix Proteins|*Cartilage|Glycosaminoglycans|Chondroitin Sulfate Proteoglycans|Extracellular Matrix|Collagen Type II|Protein Binding | |
11698404 J. Biol. Chem. 2001 Animals|Prospective Studies|*Mitogen-Activated Protein Kinases|Proto-Oncogene Proteins c-raf|MAP Kinase Signaling System|Phosphorylation|Signal Transduction|ras Proteins|EGFR protein, human|Epidermal Growth Factor Receptor|Isoforms | |
11698410 J. Biol. Chem. 2001 Humans|RPA1 protein, human|*Replication Protein A|*DNA Ligase ATP|Base Excision Repair|DNA Ligases|Single-Stranded DNA-Binding Protein|DNA Damage|DNA|T4 Phages|Base Sequence|Kinetics | |
11698416 J. Biol. Chem. 2001 Humans|Bruton type agammaglobulinemia|*Catalytic Domain|Phosphatidylinositol 3-Kinases|BTK protein, human|Bruton Tyrosine Kinase|Agammaglobulinemia|Genetic Diseases, X-Linked|*GTP-Binding Protein gamma Subunits|*GTP-Binding Protein beta Subunits|Protein-Tyrosine Kinases|Phosphorylation|Signal Transduction|platelet protein P47|Phosphoproteins|Enzyme Activation|Blood Proteins|G Proteins|TYRP1 protein, human | |
11698453 J. Immunol. 2001 Humans|CDw92 antigen|choline transporter|Endothelial Cells|CD2 Antigens|Amino Acid Sequence|*Membrane Transport Proteins|Monocytes|cDNA|Dendritic Cells|Cloning, Molecular|Membrane Glycoproteins|Antigens, CD|Base Sequence|Lymphocyte Activation|Surface Proteins|Cells, Cultured|Sequence Homology, Amino Acid | |
11698596 J. Neurosci. 2001 PMC6762276 Animals|Rats|*Cyclic AMP Response Element-Binding Protein|*Phosphorylation|*Receptor, Endothelin B|*Astrocytes|*Genes, fos|*Proto-Oncogene Proteins c-fos|Mitogen-Activated Protein Kinases|*JNK Pathway|Mitogen-Activated Protein Kinase Kinases|Signal Transduction Pathway|Mitogen-Activated Protein Kinase 3|Mitogen-Activated Protein Kinase 1|Proto-Oncogene Proteins|Protein Kinase C|MAPK, p38|c-jun N-Terminal Kinase|Proto-Oncogene Proteins c-raf|Activating Transcription Factor-1 | |
11698620 J. Neurosci. 2001 PMC6762262 Animals|*Glutamate Transporter|*Transporter, Phosphate|VGLUT2 Protein|Synaptic Vesicles|Glutamate|Vesicular Glutamate Transport Protein 1|vesicular GABA transporter|Vesicular Inhibitory Amino Acid Transport Proteins|Carrier Proteins|Presynaptic Terminal|Membrane Transport Proteins|*Brain|Vesicular Transport Proteins|Synapses|Synaptic Transmission|Biological Transport|*Cell Differentiation|Neurons | |
11698644 Proc. Natl. Acad. Sci. U.S.A. 2001 PMC61106 Rats|Animals|*Pyruvate Kinase|*Glucose|*Phosphorylation|Transcription Factor|DNA-Binding Proteins|Basic Helix-Loop-Helix Leucine Zipper Transcription Factors|8-chloro-cyclic adenosine monophosphate|*8-Bromo Cyclic Adenosine Monophosphate|Transcription, Genetic|Hepatocytes|cAMP Dependent Protein Kinase|Cell Nucleus|Promoter Regions, Genetic|Helix-Loop-Helix Domains|Leucine Zipper|Gene Expression Regulation|Liver|Response Elements | |
11700320 J. Biol. Chem. 2001 Cricetinae|Animals|adhesion receptor|*Platelet Glycoprotein GPIb-IX Complex|FLNA protein, human|*Filamins|*Platelet|Cricetulus|CHO Cells|von Willebrand Factor|Cytoplasm|Protein Binding|Binding Sites|Amino Acid Sequence|Protein Structure, Tertiary|Cell Membrane|14-3-3 Proteins | |
11700562 Nature 2001 Humans|Animals|anthrax toxin|*Bacterial Toxins|*Antigens, Bacterial|Bacillus anthracis|Anthrax|anthrax toxin receptors|Receptors, Peptide|Exotoxins|Amino Acid Sequence|Membrane Protein|Macrophages|Adenylate Cyclase|Mitogen-Activated Protein Kinase Kinases|Models, Molecular|Biological Transport | |
11701129 Cell 2001 *Caspase 7|Caspases|*Zymogens|Protein Conformation|Models, Molecular|Enzyme Activation|Dimerization|Amino Acid Sequence|Apoptosis|Substrate Specificity|Catalysis | |
11701230 Toxicol. Lett. 2001 Mice|Humans|Animals|*Benzene|*Phenol|*Isoenzymes|*Cytochrome b|*Cytochrome P450|*Phenols|CYP2E1|CYP2B6 protein, human|*Cytochrome P-450 CYP2B6|Microsomes, Liver|hydroquinone|Hydroquinones|catechol|Catechols|Liver|Lung|Cyp2f2 protein, mouse | |
11702069 Nat. Struct. Biol. 2001 Humans|LIG4 protein, human|*DNA Ligase ATP|DNA Repair|DNA Ligases|XRCC4 protein, human|DNA-Binding Proteins|Non-Homologous DNA End-Joining|DNA Breaks, Double-Stranded|Protein Binding|*Cell Nucleus|Amino Acid Sequence|BRCA1 protein, human|BRCA1 Protein|Models, Molecular | |
11702224 Hum. Genet. 2001 Male|Infant|Humans|Pregnancy|Female|*Neuraminidase|*Codon, Nonsense|Sialidosis|*Prenatal Diagnosis|*Prenatal Care|Hydrops Fetalis|Homozygote|*Lysosomes|Exon|Point Mutation|Mutation|Base Sequence|Polymerase Chain Reaction|*Fetus | |
11702237 Cell Tissue Res. 2001 Animals|Humans|DEFB1 protein, human|DEFB103A protein, human|*beta-Defensins|*Xenopus laevis|*Anti-Infective Agents|*Anti-Bacterial Agents|Amino Acid Sequence|Defensins|*Plasma Membranes|Peptides|*Chemotactic Factors|Oocytes|Macrophages | |
11702783 Dev. Cell 2001 Animals|Chlorocebus aethiops|*ERK MAP Kinases|*Peas|*Cytoplasm|Mitogen-Activated Protein Kinase 1|Mitogen-Activated Protein Kinase 3|Cell Nucleus|ERK1-2 Pathway|Export, Nuclear|Protein Binding|Phosphorylation|COS Cells|p38 Mitogen-Activated Protein Kinases|Phosphoproteins|Protein Structure, Tertiary|Amino Acid Sequence|Luminescent Proteins|Signal Transduction|Green Fluorescent Proteins | |
11703925 Dev. Cell 2001 *Endocytosis|rab5 GTP-Binding Proteins|Endosome|Guanine Nucleotide Exchange Factors|rab GTP-Binding Proteins|Vesicular Transport Proteins|Signal Transduction|*Guanine Nucleotides|Epidermal Growth Factor | |
11703931 Dev. Cell 2001 *Fluorescence Resonance Energy Transfer|Golgi Apparatus|Coat Protein Complex I|ADP-Ribosylation Factor 1|COP-Coated Vesicles|beta COP|Protein Transport|ADP-Ribosylation Factors|Endoplasmic Reticulum|GTPase-Activating Proteins|KDEL receptor|Receptors, Peptide|Membrane Proteins|Guanosine Triphosphate | |
11706020 J. Biol. Chem. 2001 Humans|Animals|interleukin-24|interleukin-22 receptor|Leukocytes, Mononuclear|*Interleukin|Receptors, Interleukin|IL10 protein, human|Interleukin-10|Cytokines|Transductions, Signal|Protein Binding|Keratinocytes | |
11706043 J. Biol. Chem. 2001 phosphatidylinositol 3-phosphate|*Phosphatidylinositol|*Phosphate|Phosphatidylinositol Phosphates|Endosomes|Amino Acid Sequence|Cell Membrane|PI-3 Kinase|Proteins|*Inositol Phosphates|Transfection|Protein Transport|Liposomes | |
11707068 Genomics 2001 Humans|GNRHR protein, human|*Receptors, LHRH|*Ribonucleoprotein|*Genome|Exons|Base Sequence|Alternative Splicing|Amino Acid Sequence|Chromosome Mapping|*Genomics|Sequence Alignment|RBM8A protein, human|RNA-Binding Proteins|Cloning, Molecular|Pseudogenes|DNA, Complementary|RNA, Messenger | |
11707391 EMBO J. 2001 PMC125729 Humans|*Catalytic Domain|*Splicings, Alternative|Protein Conformation|Binding Sites|Models, Molecular|Amino Acid Sequence|Catalysis|Crystallography, X-Ray|UTP-Hexose-1-Phosphate Uridylyltransferase|Kinetics|*Isoforms|*RNA Splicing|Glycosylation|Uridine Diphosphate N-Acetylglucosamine | |
11707405 EMBO J. 2001 PMC125738 Mice|Animals|*Phosphorylation|*T Antigen|GRB2 protein, human|GRB2 Adaptor Protein|GAB1 protein, human|*Signal Transduction|SHC1 protein, human|*Src Homology 2 Domain-Containing, Transforming Protein 1|Binding Sites|Protein Binding|src Homology Domains|EGFR protein, human|Receptor, EGF|Shc Signaling Adaptor Proteins|Phosphoproteins|Amino Acid Sequence|Tyrosine Kinase Receptors|3T3 Cells | |
11707456 J. Biol. Chem. 2001 *Glycogen Synthase Kinase 3|*Axin Protein|*Glycogen Synthase|Dictyostelium|Wnt Proteins|Signal Transduction|beta Catenin|Trans-Activators|Repressor Proteins|Protein Binding|Carrier Proteins|Binding Site|Calcium-Calmodulin-Dependent Protein Kinases|Xenopus Proteins|Phosphorylation|Proto-Oncogene Proteins|Adaptor Proteins, Signal Transducing|Zebrafish Proteins | |
11707585 Proc. Natl. Acad. Sci. U.S.A. 2001 PMC61107 Cricetinae|Animals|CHO Cells|Cricetulus|JAG1 protein, human|*Jagged-1 Protein|Serrate-Jagged Proteins|*Signal Transduction|Receptors, Notch|Membrane Proteins|Drosophila Proteins|Fucose|Intracellular Signaling Peptides and Proteins|Calcium-Binding Proteins|N-Acetylglucosaminyltransferases|Glycosylation|Epidermal Growth Factor | |
11709078 Biochem. Soc. Trans. 2001 Mitochondrial Proteins|*Ion Transport|Uncoupling Protein 1|Ion Channels|Membrane Proteins|Uncoupling Agents|Protons|Acids, Fatty|Mitochondria|Biological Transport|Adipose Tissue, Brown|Anions|Protein Transport|*Biochemical Phenomena | |
11709191 Dev. Cell 2001 Animals|Humans|protein O-mannose beta-1,2-N-acetylglucosaminyltransferase|*N-Acetylglucosaminyltransferases|*Dystrophy, Muscular|Dystroglycans|*Neuronal Migration Disorder|*Mutations|Muscle Eye Brain Disease|*Glycosyltransferases|Glycosylation|Eye Abnormalities|Muscle, Skeletal|Brain|Mannose | |
11709553 J. Biol. Chem. 2001 Humans|*Topotecan|TOP1 protein, human|*DNA Topoisomerases, Type I|*Sumoylation|Topoisomerase I Inhibitors|*Cell Nucleolus|Camptothecine|Antineoplastic Agents|Cell Nucleus|ubiquitin carrier proteins|Ubiquitin-Conjugating Enzymes|Nuclear Protein|HeLa Cells|UBE2D2 protein, human | |
11713259 J. Biol. Chem. 2001 adhesion receptor|*Platelet Glycoprotein GPIb-IX Complex|*Calcium|*Platelet Adhesiveness|alphaIIbbeta3, Integrin|von Willebrand Factor|Platelets|Platelet Activation|Calcium Spikes|2-nitrophenyl-EGTA|Egtazic Acid|*Calcium, Dietary|PI-3 Kinase | |
11713268 Mol. Cell. Biol. 2001 PMC99996 *Signal Transduction|*Membrane Microdomains|src-Family Kinases|Phosphorylation|Fc epsilon RI|Protein Binding|SH3 Domains|Plasma Membrane|*Receptor Aggregation|Mast Cells|Tyrosine Kinase|Protein Transport|Carrier Proteins|Cell Line|Ligands|Transfection|*Biochemical Phenomena|Tyrosine | |
11713293 Mol. Cell. Biol. 2001 PMC100021 Mice|Animals|*Rhodopsin|*EF Hand Motifs|*Protein Phosphatases|Drosophila|Photoreceptor Cells, Invertebrate|Retinal Degeneration|Drosophila Proteins|Electroretinography|Retina|Calcium-Binding Proteins|Phosphorylation|Mutation|Light|Hand protein, Drosophila|Basic Helix-Loop-Helix Transcription Factors | |
11713476 Nat. Struct. Biol. 2001 Animals|Humans|CTNNB1 protein, human|*beta Catenin|TCF7L1 protein, human|Transcription Factor 7-Like 1 Protein|Transcription Factors|APC protein, human|Adenomatous Polyposis Coli Protein|Trans-Activators|Transcription Factor 7-Like 2 Protein|Cadherins|Protein Binding|Binding Sites|Signal Transduction|Amino Acid Sequence|TCF4 protein, human|Transcription Factor 4 | |
11713986 Scand. J. Clin. Lab. Invest. Suppl. 2001 Mice|Animals|*mRNA|*RNA|IGF2 protein, human|*Insulin-Like Growth Factor II|*Inosine Monophosphate|RNA Binding Protein|*Protein Binding|*IGF-Binding Proteins|Protein Biosynthesis|*Protein Transport|Binding Sites|Amino Acid Sequence|Cytoplasm|*Cell Movement|Cell Proliferation|Embryogenesis | |
11714285 Biochemistry 2001 Humans|*Methionine-tRNA Ligase|glutamyl-prolyl-tRNA synthetase|Amino Acyl-tRNA Synthetases|Aminoacylation, tRNA|RNA, Transfer, Amino Acyl|RNA, Transfer, Met|Binding Sites|Escherichia coli | |
11714695 J. Biol. Chem. 2001 *Receptor, BMP|*Bone Morphogenetic Protein|BMP2 protein, human|*Bone Morphogenetic Protein 2|recombinant human bone morphogenetic protein-2|*Transforming Growth Factor beta|*Signal Transduction|Smad Proteins|Smad1 Protein|Phosphorylation|DNA-Binding Proteins|Trans-Activators|Protein-Serine-Threonine Kinases|Cell Differentiation|Transcription, Genetic|Phosphoproteins|Transfection|Alkaline Phosphatase | |
11714700 J. Biol. Chem. 2001 *Tumor Suppressor Protein p53|BIRC5 protein, human|*Survivin|Promoter Regions, Genetic|Transcription, Genetic|Cell Cycle|DNA-Binding Proteins|Cell Cycle Proteins|Apoptosis|Cyclin-Dependent Kinase Inhibitor p21|*Cell Death|E2F Transcription Factors|E2F1 Transcription Factor|Cyclins|Inhibitor of Apoptosis Proteins|Neoplasm Proteins|Microtubule-Associated Proteins|Genes, Reporter | |
11714716 J. Biol. Chem. 2001 Humans|*Survival of Motor Neuron Complex|*WD40 Repeats|Nuclear Ribonucleoproteins, Small|Muscular Atrophy, Spinal|RNA-Binding Proteins|Spliceosomes|Cell Nucleus|Cytoplasm|Nuclear Proteins|Nerve Tissue Proteins|DEAD Box Protein 20|Ribonucleoproteins|Cyclic AMP Response Element-Binding Protein|DEAD-box RNA Helicases|RNA Splicing|Amino Acid Sequence|HeLa Cells|Protein Binding | |
11714749 J. Exp. Med. 2001 PMC2193679 Mycobacterium tuberculosis antigens|*Antigens, Bacterial|antigen 85B, Mycobacterium tuberculosis|*Acyltransferases|*Bacterial Proteins|Phagosomes|Histocompatibility Antigens Class II|Mycobacterium tuberculosis|Antigen Presentation|*Major Histocompatibility Complex|*Bacillus|*Lactobacillus casei|*Peptides|Macrophages|Phagocytosis|Plasma Membrane|Interferon-gamma|*Histocompatibility Antigens | |
11715018 Nat. Cell Biol. 2001 Female|*Phosphorylation|*Tumor Suppressor Protein p53|*Proto-Oncogene Proteins c-akt|Proto-Oncogene Proteins c-mdm2|*Ubiquitination|Proto-Oncogene Proteins|Nuclear Proteins|Trans-Activators|EP300 protein, human|E1A-Associated p300 Protein|Ubiquitins|Cell Nucleus|Apoptosis|Cell Line | |
11716755 Biochem. J. 2001 PMC1222227 Humans|Male|Mice|Animals|Phosphatidylinositol 3-Kinases|PTEN protein, human|Phosphatase, PTEN|myo-inositol-1 (or 4)-monophosphatase|Signal Transduction|Amino Acid Sequence|Integral Membrane Proteins|Genes, Tumor Suppressor|Testis|Phosphatidylinositol|Plasma Membrane|Cytosol | |
11717395 Proc. Natl. Acad. Sci. U.S.A. 2001 PMC64707 Humans|HNF1A protein, human|Hepatocyte Nuclear Factor 1alpha|Nuclear Proteins|Hepatocyte Nuclear Factor 1|Hepatocyte Nuclear Factor 4|Homeodomain Proteins|Hepatocyte Nuclear Factor 1-beta|Pancreatic Islet|Promoter Regions, Genetic|Trans-Activators|Basic Helix-Loop-Helix Leucine Zipper Transcription Factors|Gene Expression Regulation|Transcription, Genetic|*Pancreas|Phosphoproteins|Mutations|Hepatocytes|*Cell Differentiation | |
11717445 Proc. Natl. Acad. Sci. U.S.A. 2001 PMC61136 Humans|CASP10 protein, human|*Caspase 10|*Caspases|CASP8 protein, human|Caspase-8|Fas-Associated Death Domain Protein|fas Receptor|Apoptosis|Caspase 9|Apoptosis Regulatory Proteins|TNF-Related Apoptosis-Inducing Ligand|Signal Transduction|Jurkat Cells|Tumor Necrosis Factor-alpha|Membrane Glycoproteins|Protein Binding | |
11717447 Proc. Natl. Acad. Sci. U.S.A. 2001 PMC61138 Humans|Mice|Dogs|Animals|intrinsic factor-cobalamin receptor|*Vitamin D 3|*Mice, Knockout|LRP2 protein, human|Megalin|*Receptors, Cell Surface|GC, vitamin D binding protein, human|Vitamin D-Binding Protein|Tubules, Proximal Renal|Endocytosis|Ligands | |
11718716 FEBS Lett. 2001 *Golgi Apparatus|RABEP1 protein, human|*Vesicular Transport Proteins|Endoplasmic Reticulum|Protein Transport|Membrane Proteins|rab GTP-Binding Proteins|Biological Transport|Guanosine Triphosphate|Endosomes|Saccharomyces cerevisiae Proteins|Protein Binding | |
11718719 FEBS Lett. 2001 Infant, Newborn|Humans|*Lung|Pulmonary Surfactant|Pulmonary Alveoli|*Alveolar Epithelial Cells|ATP-Binding Cassette Transporters|Respiratory Distress Syndrome, Newborn|*Secretory Vesicles|Surfactant Protein A|Biological Transport|Mutation|Immunoblotting|ABCA3 protein, human | |
11718896 Biochim. Biophys. Acta 2001 Animals|Humans|A1CF protein, human|*RNA-Binding Proteins|APOBEC-1|Editing, RNA|mRNA|Apolipoproteins B|RNA|Cytidine Deaminase|Base Sequence|Alternative Splicing|Amino Acid Sequence|Liver|Exons|DNA, Complementary|Cloning, Molecular|Cell Line|Gene Expression|Transfection | |
11719186 Cell 2001 Humans|Animals|*mRNA|*Exosomes|*Binding Proteins|mRNA Decay|Poly A|3' Untranslated Regions|RNA-Binding Proteins|AU Rich Elements|Saccharomyces cerevisiae | |
11719363 Blood 2001 Mice|Animals|*Erythropoiesis|STAT5A protein, human|*STAT5 Transcription Factor|*Erythroblast|Receptors, Erythropoietin|EPO protein, human|Erythropoietin|*Tumor Suppressor Proteins|Erythroid Precursor Cells|Cell Differentiation|bcl-X Protein|Signal Transduction|Anemia|DNA-Binding Proteins|Trans-Activators|Proto-Oncogene Proteins c-bcl-2|Apoptosis | |
11719518 J. Biol. Chem. 2001 Animals|Chlorocebus aethiops|*Monocarboxylic Acid Transporters|*Fluorescence Resonance Energy Transfer|Luminescent Proteins|Green Fluorescent Proteins|Membrane Glycoprotein|Basigin|Plasma Membrane|COS-7 Cells|Antigens, CD | |
11719551 J. Cell. Sci. 2001 Humans|Chlorocebus aethiops|Animals|*Connexin 26|DFNA3 protein, human|*Connexins|Gap Junctions|GJA1 protein, human|Cx43|*Protein Transport|Cyan Fluorescent Protein|Green Fluorescent Proteins|Nocodazole|Brefeldin A|Luminescent Proteins|COS Cells|Microtubule|HeLa Cells|Golgi Apparatus|Secretory Pathway|Transfection | |
11719808 Nature 2001 Mice|Animals|*Transcription Factor 3|E2F Transcription Factors|CDKN1A protein, human|Cyclin-Dependent Kinase Inhibitor p21|*Cellular Proliferation|TCF3 protein, human|*Basic Helix-Loop-Helix Transcription Factors|Cell Cycle Proteins|E2F1 Transcription Factor|E2F2 Transcription Factor|S Phase|Retinoblastoma Protein|Transcription Factor DP1|E2F3 Transcription Factor|Cell Cycle|Retinoblastoma-Binding Protein 1|Cell Division|Tumor Suppressor Protein p53 | |
11724772 J. Biol. Chem. 2001 Humans|Rats|Animals|TLR2 protein, human|*Toll-Like Receptor 2|*Peptidoglycan|*Pulmonary Surfactant-Associated Protein A|*U937 Cells|*Tumor Necrosis Factor-alpha|*Macrophages, Alveolar|Toll-Like Receptors|Receptors, Cell Surface|Nuclear Factor-Kappab|Lipopolysaccharide Receptors|Cell Signaling|Membrane Glycoproteins|Lipopolysaccharides|Protein Binding|Drosophila Proteins|Transfections|Cell Line | |
11724780 J. Biol. Chem. 2001 Rats|Animals|*AMP-Activated Protein Kinases|*Glucose|*Transcription Factor|DNA-Binding Proteins|Basic Helix-Loop-Helix Leucine Zipper Transcription Factors|Pyruvate Kinase, L-Type|*Acids, Fatty|Transcription, Genetic|Phosphorylation|AICA ribonucleotide|Ribonucleotides|Hepatocytes|Aminoimidazole Carboxamide|Promoter Regions, Genetic|Gene Expression Regulation|Liver|Transfection | |
11724816 J. Cell Biol. 2001 PMC2150881 Animals|Mice|ANK2 protein, human|*Ankyrins|betaIV spectrin|*Spectrin|*Purkinje Cells|*Axon Initial Segment|*L1 Cell Adhesion Molecule|Ranvier's Nodes|Nerve Tissue Proteins|*Voltage-Gated Sodium Channels|Axons|NRCAM protein, human|Cell Adhesion Molecules|Neurons|Nerve Growth Factors|Protein Isoforms | |
11724925 Proc. Natl. Acad. Sci. U.S.A. 2001 PMC64676 *DNA Polymerase III|*Flap Endonucleases|*Proliferating Cell Nuclear Antigen|Okazaki fragments|*Replication Protein A|DNA|DNA Replication|DNA Primers|*Chromosome Structures|RNA|Nucleotides|*Recombination, Genetic | |
11726282 J. Biochem. 2001 Humans|Swine|Rats|Animals|N-acyl-D-glucosamine 2-epimerase|*Nucleotides|*Renin|*Epimerases|*Glucosamine|Carbohydrate Epimerases|RENBP protein, human|Carrier Proteins|2'-deoxyadenosine triphosphate|Deoxyadenine Nucleotides|2',3'-dideoxyadenosine triphosphate|Dideoxynucleotides|Amino Acid Sequence|Kidney|Catalytic Domain|Escherichia coli|Thermolysin | |
11726503 EMBO J. 2001 PMC125773 *Phosphorylation|*Proteolysis|*Cytoplasm|CDKN1B protein, human|Cyclin-Dependent Kinase Inhibitor p27|CDK2 protein, human|Cyclin-Dependent Kinase 2|Cell Nucleus|G1 Phase|Export, Nuclear|Resting Phase, Cell Cycle|Mutation|Serine|*Cytosol | |
11726511 EMBO J. 2001 PMC125325 *ADP-Ribosylation Factor 1|*Golgi Apparatus|Coatomer Protein|Intracellular Membranes|Guanosine Triphosphate|Protein Binding|Binding Sites|Amino Acid Sequence|Carrier Proteins|Nucleotides | |
11726970 Nat. Med. 2001 Humans|Animals|*Influenza A virus|*Protein A|*Mitochondria|Influenza|Influenza A Virus, H1N1 Subtype|Viral Proteins|Amino Acid Sequence|*Cell Death|Apoptosis|Cell Line|Mitochondrial Proteins | |
11727826 Biol. Chem. 2001 Animals|Humans|tRNA nucleotidyltransferase|*RNA Nucleotidyltransferases|Polymerase, Poly A|Amino Acid Sequence|Base Sequence|tRNA|*Eubacterium|Sequence Alignments|*Eubacteria|Nucleotidyltransferases|Sequence Homology, Amino Acid|Substrate Specificity|Baker Yeast | |
11728342 Immunity 2001 *Receptor, IL-7|*Histones|*Acetylation|*Receptors, Antigen, T-Cell, gamma-delta|STAT5A protein, human|*STAT5 Transcription Factor|*Tumor Suppressor Proteins|Transcription, Genetic|Promoter Regions, Genetic|Thymocytes|DNA-Binding Proteins|Signal Transduction|Protein Binding|Germ Line|*Protein Processing, Post-Translational|Cell Line|Cytokines | |
11728344 Immunity 2001 Humans|TNFSF12 protein, human|*Cytokine TWEAK|TNFRSF12A protein, human|TWEAKR|TNF protein, human|*Tumor Necrosis Factor-alpha|*Carrier Proteins|Receptors, Tumor Necrosis Factor|Apoptosis Regulatory Proteins|Cell Movement|Ligands|Signal Transduction|Apoptosis|Cell Division|Endothelium, Vascular|*Morphogenesis | |
11729324 Science 2001 *Cell Survival|NGFR protein, human|Receptors, Nerve Growth Factor|NGF protein, human|Nerve Growth Factor|BDNF protein, human|Brain-Derived Neurotrophic Factor|Receptor, trkA|Receptor, Nerve Growth Factor|Neurons|Nerve Tissue Proteins|Protein Precursors|Carrier Proteins|Protein Binding|Cells, Cultured|Apoptosis|Cell Death | |
11731253 Mech. Dev. 2001 Female|Mice|Animals|Humans|*Oogenesis|*Oocytes|Blastocyst|Transcription Factors|*Embryogenesis|Homeodomain Proteins|cDNA|Amino Acid Sequence|Ovarian Follicle|Mesoderm|Base Sequence|Gene Expression Regulation, Developmental|Blotting, Northern|Cloning, Molecular|Ovaries | |
11733379 Am. J. Pathol. 2001 PMC1850607 Mice|Animals|nephrin|*Membrane Proteins|Cytoskeletal Proteins|Adaptor Proteins, Signal Transducing|*Intercellular Junctions|Intracellular Signaling Peptides and Proteins|Podocytes|Kidney Glomerulus|SH3 Domains|Kidney|Cell Line|Epithelial Cells|Microscopy, Immunoelectron | |
11733541 J. Biol. Chem. 2001 Mice|Animals|myotubularin|phosphatidylinositol 3-phosphate|Charcot-Marie-Tooth disease, Type 4B1|*Charcot-Marie-Tooth Disease|phosphatidylinositol-3-phosphatase|*Protein Tyrosine Phosphatases, Non-Receptor|*Myotubular Myopathy|Phosphatidylinositol Phosphates|Protein Tyrosine Phosphatase|Phosphatidylinositols|Amino Acid Sequence | |
11733556 J. Clin. Invest. 2001 PMC200991 Cricetinae|Animals|Humans|*Glycosylation|CHO Cells|Cricetulus|Congenital disorder of glycosylation type 1F|*Congenital Disorders of Glycosylation|*Mutation|Mannosyltransferases|Homozygote|Amino Acid Sequence|Mannose|Fibroblasts|Seizures|Oligosaccharides | |
11733557 J. Clin. Invest. 2001 PMC200981 nephrin|NPHS2 protein|*Integral Membrane Proteins|*Intracellular Signaling Peptides and Proteins|*Kidney Glomerulus|Nephrotic syndrome, idiopathic, steroid-resistant|Nephrotic Syndrome|Nephrosis, congenital|Cytoskeletal Proteins|*Intercellular Junctions|Adaptor Proteins, Signal Transducing|Mutations|Microscopy, Immunoelectron | |
11733564 J. Clin. Invest. 2001 PMC200989 Humans|*Glycosylation|Congenital Disorders of Glycosylation|*Mutations|Mannosyltransferases|Amino Acid Sequence|Oligosaccharides|Proteins|Fibroblasts | |
11734543 Hum. Mol. Genet. 2001 Humans|*Charcot-Marie-Tooth Disease|connexin 32|*Junction Protein, Gap|*SOXE Transcription Factors|Waardenburg syndrome, type 4|Waardenburg Syndrome|DNA-Binding Proteins|High Mobility Group Proteins|Transcription Factors|Promoter Regions, Genetic|Mutation|*Genes, X-Linked|Hirschsprung Disease|SOX10 protein, human | |
11734551 J. Biol. Chem. 2001 Animals|Humans|*Copper|Cation Transport Proteins|Plasma Membrane|Biological Transport|Membrane Proteins|Cell Line|Amino Acid Sequence|Blotting, Western|Cytoplasm|Microscopy, Fluorescence|Copper Transport Proteins | |
11734571 J. Lipid Res. 2001 Animals|Humans|Mice|Peroxisomal ACYL-COA oxidase deficiency|Adrenoleukodystrophy|tetracosahexaenoic acid|*Docosahexaenoic Acids|Peroxisomes|Zellweger Syndrome|Acyl-CoA Oxidase|Oxidation-Reduction|Linolenic Acid|Acetyl-CoA C-Acyltransferase|Mitochondria|Fibroblasts|Fatty Acids|Mice, Knockout|sterol carrier proteins|Carrier Proteins|Lipid Metabolism, Inborn Errors | |
11734640 Proc. Natl. Acad. Sci. U.S.A. 2001 PMC64668 CASP9 protein, human|*Caspase 9|*Caspases|APAF1 protein, human|Apoptotic Protease-Activating Factor 1|Dimerization|Protein Conformation|Enzyme Activation|Apoptosis|Crystallography, X-Ray|Active Site|Models, Molecular|Amino Acid Sequence|Kinetics|Catalysis|Enzyme Precursors|Macromolecular Substances|Models, Biological | |
11734858 Nature 2001 Bartter syndrome, antenatal type 1|Bartters Syndrome|BSND protein, human|*Chloride Channels|*Renal Reabsorption|Integral Membrane Protein|Point Mutation|Anion Transport Proteins|*Ear, Inner|Mutations|Cell Membrane|Patch-Clamp Techniques|Kidney|*Chlorides|Solute Carrier Family 12, Member 1|*Potassium | |
11735028 Hum. Genet. 2001 Humans|*Holocarboxylase Synthetase Deficiency|holocarboxylase synthetases|Carbon-Nitrogen Ligases|Multiple Carboxylase Deficiency|*Mutation|Exons|Biotin|cDNA | |
11735126 Biochem. Biophys. Res. Commun. 2001 Animals|SUMO-1 Protein|Ubiquitin-Conjugating Enzymes|DNA methyltransferase 3B|*DNA (Cytosine-5-)-Methyltransferases|Small Ubiquitin-Related Modifier Proteins|Binding Sites|Ubiquitin-Protein Ligases|Protein Inhibitors of Activated STAT|Repressor Proteins|*DNA Modification Methylases|DNA | |
11737239 Eur. J. Clin. Invest. 2001 *Insulin|*Signal Transduction|GRB2 protein, human|GRB2 Adaptor Protein|Insulin Receptor Substrate Proteins|IGF1 protein, human|Insulin-Like Growth Factor I|Phosphoproteins|Phosphorylation|Tyrosine Kinase|Phosphotyrosine|src Homology Domains|SHC1 protein, human|Src Homology 2 Domain-Containing, Transforming Protein 1|PTPN11 protein, human|Protein Tyrosine Phosphatase, Non-Receptor Type 11|DNA-Binding Proteins|STAT5 Transcription Factor | |
11738041 Structure 2001 CTNNB1 protein, human|*beta Catenin|*Phosphorylation|*Glycogen Synthase Kinase 3 beta|Glycogen Synthase Kinase 3|*Peptides|Axin Protein|Wnt Proteins|Trans-Activators|Binding Protein|Calcium-Calmodulin-Dependent Protein Kinases|Repressor Proteins|Protein Binding|Signal Transduction|Amino Acid Sequence|Zebrafish Proteins|Sequence Homology, Amino Acid | |
11738050 Structure 2001 Humans|AUH protein, human|*Enoyl-CoA Hydratase|*RNA-Binding Proteins|Amino Acid Sequence|Protein Conformation|Binding Sites|Models, Molecular|Crystallography, X-Ray|RNA|Sequence Homology, Amino Acid|Acyl Coenzyme A|Coenzyme A|Catalysis|Mutagenesis, Site-Directed | |
11738596 Trends Biochem. Sci. 2001 rho GTPases|cdc42 GTP-Binding Protein|Rho Guanine Nucleotide Exchange Factors|Amino Acid Sequence|Signal Transduction|Proto-Oncogene Proteins|Sequence Homology, Amino Acid | |
11739018 J. Endocrinol. 2001 Humans|*Triiodothyronine|*Arylsulfotransferase|*Isoenzymes|Sulfotransferases|4-nitrophenol|Nitrophenols|Substrate Specificity|Thyroxine|*Liver|Kinetics|Alleles|cDNA|Platelets|SULT1A1 protein, human | |
11739083 Am. J. Physiol. Endocrinol. Metab. 2001 IGFBP3 protein, human|*Insulin-Like Growth Factor Binding Protein 3|*Fibrinolysin|*Thrombin|Iodine-125|*Iodine Radioisotopes|*Proteolysis|*Endothelial Cells|Insulin-Like Growth Factor Binding Protein 4|Insulin-Like Growth Factor I|Proteases|Heparin|Protein Binding|peptide P3|Carrier Proteins|Amino Acid Sequence|Peptide Fragments|Binding Sites | |
11739186 Blood 2001 Humans|FGFR1 protein, human|*Receptor, Fibroblast Growth Factor, Type 1|In Situ Hybridization, Fluorescence|*Leukemia, Myelogenous, Chronic, BCR-ABL Positive|Myeloproliferative Disorder|Fusion Proteins, bcr-abl|Proto-Oncogene Proteins c-bcr|ZMYM2 protein, human|DNA-Binding Proteins|Translocation, Genetic|Transcription Factors|Proto-Oncogene Proteins|Phosphorylation | |
11739383 J. Biol. Chem. 2001 Humans|HDAC10 protein, human|*Histone Deacetylase|HDAC6 protein, human|Histone Deacetylase 6|Amino Acid Sequence|Base Sequence|cDNA|Cloning, Molecular|Transfections|Acetylation|Chromosome Mapping|Sequence Homology, Amino Acid|Exons|Cell Line|Gene Expression | |
11739401 J. Cell Biol. 2001 PMC2150909 *Golgi Apparatus|Golgin subfamily A member 2|Membrane Proteins|*Protein Transport|Golgi Matrix Proteins|Endoplasmic Reticulum|Autoantigens|Protein Binding|Biological Transport|Amino Acid Sequence | |
11739720 Mol. Cell. Biol. 2001 PMC134219 *RNA Polymerase II|Transcription, Genetic|Uridine Triphosphate|Promoter Regions, Genetic|Cytidine Triphosphate|RNA, Bacterial|Guanosine Triphosphate|Nucleotides|Adenosine Triphosphate|Base Sequence | |
11739726 Mol. Cell. Biol. 2001 PMC134224 Humans|Cricetinae|Animals|ORC2 protein, human|*Origin Recognition Complex|*Chromatin|*Division Cycle, Cell|S Phase|Cell Nucleus|*Ubiquitin|DNA Replication|*Mammals|ATP dependent 26S protease|Proteasome Endopeptidase Complex|Cell Division|Cytoplasm|Protein Binding|HeLa Cells | |
11739732 Mol. Cell. Biol. 2001 PMC134215 Mice|Animals|ras Proteins|Endopeptidases|*Cell Transformation, Neoplastic|Protein Processing, Post-Translational|*Cell Proliferation|Fibroblasts|Cell Line|Cells, Cultured|Cell Membrane|Methylation|*Cell Cycle|Enzyme Inhibitors | |
11739738 Mol. Cell. Biol. 2001 PMC134221 Humans|*Nuclear Pore|*Active Transport, Cell Nucleus|Nucleoporin|Nucleocytoplasmic Transport Proteins|*RNA Transport|Karyopherins|*Dimerization|RNA-Binding Proteins|mRNA|Nuclear Proteins|Cell Nucleus|Protein Binding|Binding Sites|RNA|Amino Acid Sequence|ATP-Binding Cassette Transporters|Cell Line|NXT1 protein, human | |
11739780 Mol. Biol. Cell 2001 PMC60755 *Saccharomyces cerevisiae|*Golgi Apparatus|*Endoplasmic Reticulum|Saccharomyces cerevisiae Proteins|Vesicular Transport Proteins|SNARE|*Yeast, Dried|Carrier Proteins|Protein Binding|Membrane Fusion|Amino Acid Sequence|Coat Protein Complex I | |
11740489 Nat. Cell Biol. 2001 Humans|*Tumor Suppressor Protein p53|HIPK2 protein, human|*Serine Threonine Kinase|*Carrier Proteins|Phosphorylation|Nuclear Proteins|Transcription Factors|Apoptosis|Tumor Suppressor Proteins|Promyelocytic Leukemia Protein|Cell Cycle|CREBBP protein, human|CREB-Binding Protein|Cell Proliferation|Ultraviolet Radiation|DNA Damage|Serine | |
11740563 Nature 2001 Animals|Humans|*Cytosol|p97 ATPase|*ATPase|*Endoplasmic Reticulum|*Nuclear Proteins|Saccharomyces cerevisiae|Saccharomyces cerevisiae Proteins|Proteasome|Cell Cycle Proteins|Valosin Containing Protein|Ubiquitin|Nucleocytoplasmic Transport Proteins|Vesicular Transport Proteins|Nuclear Pore Complex Proteins|Nsfl1c protein, rat|Soluble N-Ethylmaleimide-Sensitive Factor Attachment Proteins|Ubiquitination|Protein Folding | |
11740938 Dev. Cell 2001 Animals|*Kinetochores|*Chromosome Segregation|*Chromatids|centromere protein C|Chromosomal Proteins, Non-Histone|cohesins|Cell Cycle Proteins|Anaphase|Nuclear Proteins|Centromeres|Spindle Apparatus|Mitosis|Saccharomyces cerevisiae Proteins|Phosphoproteins|DNA-Binding Proteins|*Vertebrate | |
11740940 Dev. Cell 2001 Animals|*Drosophila|*Ubiquitin|Drosophila Proteins|Drosophila melanogaster|E3 Ubiquitin Ligase|Receptors, Notch|Endocytosis|Membrane Proteins|Intracellular Signaling Peptides and Proteins|Wings, Animal|Nerve Tissue Proteins|Signal Transduction | |
11741232 AAPS PharmSci 2001 PMC2751030 Pregnancy|Female|Humans|Animals|Rats|Mice|*Protons|*Computational Biology|peptide permease|Membrane Transport Proteins|*Biological Transport|cDNA|*Oligopeptides|Peptide Transporter 1|Symporters|Amino Acid Sequence|Introns|Expressed Sequence Tags|Exons|*Ion Transport | |
11741323 Biochem. Biophys. Res. Commun. 2001 Humans|*Glucose Transport Facilitators|*Cloning, Molecular|Amino Acid Sequence|cDNA|Exons|Base Sequence|Transcription, Genetic|Chromosome Mapping|Sequence Homology, Nucleic Acid|Monosaccharide Transport Proteins|Genome, Human|RNA, Messenger|Sequence Homology, Amino Acid|Protein Structure, Secondary | |
11741533 Mol. Cell 2001 *MAP Kinase, p38|*PPAR gamma|PPARGC1A protein, human|*Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha|*Mitogen-Activated Protein Kinase 14|*Energy Expenditure|Transcription Factors|Phosphorylation|DNA-Binding Proteins|Trans-Activators|Cell Line|MAP Kinase Signaling System|Signal Transduction|Muscle, Skeletal|*Cytokines | |
11741534 Mol. Cell 2001 Animals|Mice|Chlorocebus aethiops|*Phosphorylation|KSR-1 protein kinase|*Signal Transduction|Mitogen-Activated Protein Kinase Kinases|Proto-Oncogene Proteins c-raf|ras Proteins|COS Cells|3T3 Cells|Proto-Oncogene Proteins|Plasma Membrane | |
11741535 Mol. Cell 2001 *Proto-Oncogene Proteins c-met|CBL protein, human|Proto-Oncogene Proteins c-cbl|*Mutation|Protein Binding|Proto-Oncogene Proteins|Ubiquitin|Phosphorylation|Ubiquitin-Protein Ligases|Signal Transduction|Tyrosine|Binding Site|Cell Transformation, Neoplastic|Down-Regulation|*Protein Domains | |
11741541 Mol. Cell 2001 Animals|*Phosphorylation|transcription factor UBF|Pol1 Transcription Initiation Complex Proteins|RNA Polymerase I|*Ribosomes|Transcription, Genetic|Transcription Factors|MAPK3 protein, human|Mitogen-Activated Protein Kinase 3|Activation, Transcription|DNA, Ribosomal|Promoter Regions, Genetic|*Mammals|HMGB1 Protein | |
11741893 J. Biol. Chem. 2001 Animals|Humans|*Germinal Center Kinases|Protein-Serine-Threonine Kinases|Mitogen-Activated Protein Kinases|Phosphorylation|Amino Acid Sequence|Saccharomyces cerevisiae Proteins|Intracellular Signaling Peptides and Proteins|CASP3 protein, human|Caspase 3|Apoptosis|Sequence Homology, Amino Acid|Cloning, Molecular|*Mammals|MBP protein, human|Myelin Basic Protein | |
11742004 J. Biol. Chem. 2001 Mice|Animals|*Cysteine|*Wnt Signaling Pathway|NIH 3T3 Cells|Wnt Proteins|Phosphoproteins|Adaptor Proteins, Signal Transducing|Dishevelled Proteins|beta Catenin|Axin Protein|Protein Binding|Proto-Oncogene Proteins|Trans-Activators|Repressor Proteins|Zebrafish Proteins|Phosphorylation | |
11742120 Protein Sci. 2001 PMC2368771 BTK protein, human|*Agammaglobulinaemia Tyrosine Kinase|Tec protein-tyrosine kinase|Protein-Tyrosine Kinases|src Homology Domains|Protein Binding|*Dimerization|Amino Acid Sequence|Binding Sites|Proline|Signal Transduction|Models, Molecular|Phosphorylation|Nuclear Magnetic Resonance | |
11742988 EMBO J. 2001 PMC125337 *Type A Cyclin|*Mitosis|Cell Cycle Proteins|Anaphase-Promoting Complex-Cyclosome|Cdc20 Proteins|Protein-Serine-Threonine Kinases|Spindle Assembly Checkpoint|Centrosome|NIMA-Related Kinases|Type B Cyclin|Amino Acid Sequence | |
11743735 J. Mol. Biol. 2001 Mice|Animals|*Prion Proteins|*Neural Cell Adhesion Molecules|Tandem Mass Spectrometry|*Prions|PrPSc Proteins|PrPC Proteins|Protein Binding|Binding Site|*Biophysical Phenomena | |
11744609 Drug Metab. Dispos. 2001 Animals|Humans|Rabbits|dimethylaniline monooxygenase (N-oxide forming)|*Oxygenases|*Lung|Microsomes|*Protein Isoforms|NADPH|Kinetics|diphenylthiourea|Thiourea|*Protein Processing, Post-Translational | |
11744692 J. Biol. Chem. 2001 Humans|X-ray repair cross complementing protein 3|*DNA-Binding Proteins|XRCC2 protein, human|RAD51C protein, human|RAD51 protein, human|Rad51 Recombinase|DNA Repair|Recombinant Proteins|Recombination, Genetic|Protein Binding|HeLa Cells|DNA|Cell Nucleus|RAD51B protein, human | |
11744733 J. Biol. Chem. 2001 Humans|*Transactivator|*Transcription Factor AP-2|CREBBP protein, human|*CREB-Binding Protein|Transcription Factors|Nuclear Proteins|Transcription, Genetic|EP300 protein, human|*E1A-Associated p300 Protein|Transcriptional Activation|Promoter Regions, Genetic|Cell Nucleus|Protein Binding|Transfection|Plasmids|Protein Structure, Tertiary|Amino Acid Sequence|CITED4 protein, human | |
11746448 J. Neurosci. Res. 2001 Rats|Humans|Animals|HeLa Cells|*Golgi Apparatus|Intracellular Membrane|Protein Transport|trans-Golgi Network|Endosomes|Transport Vesicles|rab GTP-Binding Proteins|*Oligodendrocyte|Membrane Proteins|Cell Compartmentation|Plasma Membrane|Receptor, IGF Type 2|Myelin | |
11746989 Genes Chromosomes Cancer 2001 *Microsatellite Instability|*Wnt Signaling Pathway|CTNNB1 protein, human|beta Catenin|*Colorectal Cancer|Transcription Factors|Genes, APC|Wnt Proteins|T Cell Factor 4|Trans-Activators|Axin Protein|Mutations|Adenomatous Polyposis Coli|Proto-Oncogene Proteins|DNA Mutational Analysis|Gene Expression Regulation, Neoplastic|Repressor Proteins|Zebrafish Proteins | |
11747420 Biochemistry 2001 *NAD|Oxygen-18|*Oxygen Isotopes|Silent Information Regulator Proteins, Saccharomyces cerevisiae|O Acetyl ADP Ribose|Sirtuin 2|ADP-Ribose|*Gene Silencing|Acetylation|Protein Processing, Post-Translational|Hydrolysis|Histones|Niacinamide|Kinetics|Amino Acid Sequence|Catalysis | |
11747816 Curr. Biol. 2001 *Actins|*Arp2-3 Complex|Actin-Related Protein 3|Actin-Related Protein 2|Microfilament Proteins|Wiskott-Aldrich Syndrome Protein|Wiskott-Aldrich Syndrome Protein Family|Filaments, Actin|Wiskott-Aldrich Syndrome|TYRP1 protein, human|*Membrane Glycoproteins|Amino Acid Sequence | |
11747826 Curr. Biol. 2001 Mice|Animals|*Histones|coactivator-associated arginine methyltransferase 1|*Methylation|*Arginine|*Protein-Arginine N-Methyltransferases|*Promoter Regions, Genetic|Acetylation|Chromatin|G-T mismatch-binding protein|DNA-Binding Proteins|Gene Activation|Nuclear Proteins|Transcription, Genetic|Lysine|Nuclear Hormone Receptors|Chromatin Immunoprecipitation|Protein Binding|*Posttranslational Modifications | |
11748146 Development 2001 Mice|Animals|*Progenitor Cells|FGF10 protein, human|*Fibroblast Growth Factor 10|*Pancreas|Cell Differentiation|Mesenchyme|*Organogenesis|Fibroblast Growth Factors|Endoderm|Signal Transduction|Epithelial Cells|Organ Cultures|Cell Division|Gene Expression Regulation, Developmental|Homeodomain Proteins|Fgf10 protein, mouse | |
11748230 J. Biol. Chem. 2001 Humans|*Survival of Motor Neuron Complex|Nuclear Ribonucleoproteins, Small|Muscular Atrophy, Spinal|Spliceosomes|RNA-Binding Proteins|Nuclear Proteins|Cytoplasm|Nerve Tissue Proteins|Immunoprecipitation|Cell Nucleus|Amino Acid Sequence|Motor Neurons|Protein Binding|Cyclic AMP Response Element-Binding Protein|HeLa Cells | |
11748249 J. Cell Biol. 2001 PMC2199348 COP-Coated Vesicles|Coat Protein Complex I|Golgi Apparatus|ADP-Ribosylation Factor 1|*Protein Transport|Coatomer Protein|ADP-Ribosylation Factors|Intracellular Membranes|GTPase-Activating Proteins|SNARE|mannosyl-oligosaccharide 1,3 - 1,6-alpha-mannosidase|Mannosidases|Guanosine Triphosphate|Organelles|Liposomes|Protein Binding|Hydrolysis | |
11748924 Cell. Immunol. 2001 Humans|*Leptin|*Phosphatidylinositol 3-Kinases|*Leukocytes, Mononuclear|leptin receptor, human|Leptin Receptor|Signal Transduction Pathways|Phosphorylation|RNA Binding Protein|MAP Kinase Signaling System|Adaptor Proteins, Signal Transducing|Proto-Oncogene Proteins c-akt|Insulin Receptor Substrate Proteins|Trophoblasts|*Cell Cycle Proteins | |
11751416 Cancer Res. 2001 Humans|Mice|Animals|Child|*PI3-Kinase|*Protein Tyrosine Kinase|*Proto-Oncogene Proteins c-akt|NIH 3T3 Cells|MAPK3 protein, human|*Mitogen-Activated Protein Kinase 3|*Signal Transduction|*Phosphatidylinositol 3-Kinase|PIK3CG protein, human|*Class Ib Phosphatidylinositol 3-Kinase|*Receptor Protein-Tyrosine Kinases|Proto-Oncogene Proteins |
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