Here's a good question: if we are living in a simulation, what are our expectations? If we study whether or not that's true, what is the most logical evidence we'd expect to find? I would posit that we'd have to somehow discover inconsistencies that don't seem to make sense, unless viewed from the lens of being in a simulation. For example, maybe we start looking really closely at the world, to the smallest particles and suddenly the laws of physics seem to flip around and stop making sense. If we saw that, we'd almost have to conclude the most logical explanation is that we're looking at the rules of the substrate our simulation is running on. Due to memory access and stuff like that, those substrate rules would probably break all sorts of locality laws and stuff.
Imagine if that was the case, how weird would that be?