Skip to content

Instantly share code, notes, and snippets.

@Tabea-K
Created February 6, 2019 12:37
Show Gist options
  • Save Tabea-K/78f8b6a129ff7151ddc717f66202a7e4 to your computer and use it in GitHub Desktop.
Save Tabea-K/78f8b6a129ff7151ddc717f66202a7e4 to your computer and use it in GitHub Desktop.
Definition of MuTect2 filters, taken from vcf header.

Definition of MuTect filters

Filter Description
alt_allele_in_normal Evidence seen in the normal sample
clustered_events Clustered events observed in the tumor
germline_risk Evidence indicates this site is germline, not somatic
homologous_mapping_event More than three events were observed in the tumor
multi_event_alt_allele_in_normal Multiple events observed in tumor and normal
panel_of_normals Seen in at least 2 samples in the panel of normals
str_contraction Site filtered due to contraction of short tandem repeat region
t_lod_fstar Tumor does not meet likelihood threshold
triallelic_site Site filtered because more than two alt alleles pass tumor LOD
Sign up for free to join this conversation on GitHub. Already have an account? Sign in to comment