Exemplo de um Echo Bot usando Webhook. LIB: Telepot

bot.py

import telepot
from telepot.loop import OrderedWebhook
from flask import Flask, request

app = Flask(__name__)

token = ''
#Test used Localtunnel
#Run: lt --port 8000 -s tergvffgs
url = 'https://tergvffgs.localtunnel.me'
url_path = '/secret-path'
port = 8000

bot = telepot.Bot(token)

@app.route(url_path, methods=['POST'])
def _():
	webhook.feed(request.data)
	return '{}'

def echo(msg):
	bot.sendMessage(msg['chat']['id'], msg['text'])

bot.setWebhook(url + url_path)
webhook = OrderedWebhook(
	bot,
	{'chat': echo}
)

def main():
	webhook.run_as_thread()
	app.run(
		host='0.0.0.0',
		port=port,
		debug=True
	)

if __name__ == '__main__':
	main()