Autophagy, starving, Ozempic: the internet’s new health triangle
I kept seeing posts worshipping autophagy like it’s a free car wash for your cells, so I asked my ChatGPT researcher to pull the signal from the noise. The theme surprised me: the biology is real, the claims are way ahead of the data.
Quick refresher: autophagy is your cell’s recycling bin. Low nutrients = your body takes out the trash. That part is solid. The leap to “starving prevents aging and cancer” is where it breaks.
Here’s the snag I didn’t expect: in humans we rarely measure autophagy directly - it’s invasive. Most “anti-aging/cancer” excitement comes from yeast, worms, mice. In people, fasting improves weight, insulin, maybe inflammation. That’s good. But “live longer and never get cancer”? Not proven.
Also, cancer is weird with autophagy. Early on, cleanup may reduce damage. Later, tumors can hijack autophagy to survive stress. So “more autophagy” is not a universal good - some trials even try blocking it in cancer therapy. That f