The private.xml for KeyRemap4MacBook to remap Caps Lock to Hyper (Control + Shift + Option + Command). First, you need to disable Caps Lock through Keyboard Preference and remap Caps Lock to PC Application(keycode:110) using PCKeybaordHack.

private.xml

<?xml version="1.0"?>
<root>
<item>
    <name>Remap PC Application to Hyper</name>
    <appendix>OS X doesn't have a Hyper. This maps PC Application to Control + Shift + Option + Command.</appendix>

    <identifier>pc_application_to_hyper</identifier>

    <autogen>
        --KeyToKey--
        KeyCode::PC_APPLICATION,

        KeyCode::COMMAND_L,
        ModifierFlag::OPTION_L | ModifierFlag::SHIFT_L | ModifierFlag::CONTROL_L
    </autogen>
</item>
</root>