gistfile1.txt

Load my-view1.clj and enter at the REPL:
my-view1=> (dev-init #'init-my-view1)

You should see a Window appear with a button.
Pressing F5 will cause the view to reload (including reloading the XAML from the disk).

my-view1.clj

(ns my-view1
  (:use
   [ClojureWpf.core])
  (:import
   [System.Windows MessageBox]))

(defn- on-hello-click [s e]
  (MessageBox/Show "You clicked hello"))

(defn init-my-view1 []
  (let [view (load-dev-xaml "MyView1.xaml")]
    (at [view :btnHello] :Click #'on-hello-click)
    view))

MyView1.xaml

<UserControl x:Class="MyView1"
    xmlns="http://schemas.microsoft.com/winfx/2006/xaml/presentation"
    xmlns:x="http://schemas.microsoft.com/winfx/2006/xaml"
    Height="650" Width="575">
    <Grid>
      <Button x:Name="btnHello">Hello World</Button>
    </Grid>
</UserControl>