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adamtongji / ensembl_vep_86_with_offline_cache.md
Created May 8, 2018 05:48 — forked from ckandoth/ensembl_vep_86_with_offline_cache.md
Install Ensembl's VEP v86 with various caches for running offline

Ensembl's VEP (Variant Effect Predictor) is popular for how it picks a single effect per gene as detailed here, its CLIA-compliant HGVS variant format, and Sequence Ontology nomenclature for variant effects.

To follow these instructions, we'll assume you have these packaged essentials installed:

## For Debian/Ubuntu system admins ##
sudo apt-get install -y build-essential git libncurses-dev

## For RHEL/CentOS system admins ##
sudo yum groupinstall -y 'Development Tools'
sudo yum install -y git ncurses-devel