Alice Braun alicebraun
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| ########### | |
| #PGC_GPRS.R | |
| #Polygenic Score Analysis from PLINK PRS-CS or C-PT output | |
| ########### | |
| # libraries | |
| library(Hmisc) | |
| library(plyr) | |
| library(rms) | |
| library(pROC) |
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| ############################################################ | |
| # Effective N calculation for individual samples # | |
| ############################################################ | |
| # From RICOPILI daner format | |
| extract_frq <- function(df) { | |
| # Identify columns for cases (FRQ_A_*) and controls (FRQ_U_*) | |
| case_cols <- grep("^FRQ_A_\\d+$", colnames(df), value = TRUE) | |
| control_cols <- grep("^FRQ_U_\\d+$", colnames(df), value = TRUE) | |