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Created July 26, 2017 17:59
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WP554_77712.json
{
"Name": "ACE Inhibitor Pathway",
"Organism": "Homo sapiens",
"License": "CC BY 2.0",
"Comment": [
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"Source": "WikiPathways-category",
"content": "Physiological Process"
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"content": "The core of this pathway was elucidated over a century ago and involves the conversion of angiotensinogen to angiotensin I (Ang I) by renin, its subsequent conversion to angiotensin II (Ang II) by angiotensin converting enzyme. Ang II activates the angiotensin II receptor type 1 to induce aldosterone synthesis, increasing water and salt resorption and potassium excretion in the kidney and increasing blood pressure.\n\nSource: PharmGKB (http://www.pharmgkb.org/do/serve?objId=PA2023&objCls=Pathway)"
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