Stylish

/*fixed元素*/
.is-fixed {
	position: static !important;
	display:none;
}
/*专栏页头*/
.ColumnPageHeader-Wrapper {
	display:none;
}
/*头部logo*/
.ZhihuLogoLink {
	display:none;
}
/*主体容器*/
.Topstory-container, .SearchMain, .Question-main {
    width: 100%;
    max-width: 1000px;
    display:block;
}

/*右边栏*/
.GlobalSideBar, .SearchSideBar, .Question-sideColumn {
	display:none;
}
/*左边栏*/
 .Topstory-mainColumn, .Question-mainColumn {
    margin-right: 0;
    width: 100%;
    max-width: 1000px;
}
/*整体容器*/

/*左边缩略图*/
.RichContent-cover {
	display:none;
}
/*actions*/
.Topstory-container .ContentItem-actions, .SearchMain .ContentItem-actions {
	display:none;
}
/*文章顶部全屏图片*/
.TitleImage--fullScreen{
	display:none;
}

tampermonkey

// ==UserScript==
// @name         屏蔽知乎首页推荐中的广告和肖战
// @namespace    http://tampermonkey.net/
// @version      0.1
// @description  不知道为什么总是给我推荐标题特别恶心充满脑残气息的帖子，知乎推荐算法太垃圾了
// @author       Ava
// @match        https://www.zhihu.com/
// @grant        none
// ==/UserScript==

(function () {
    'use strict';

    function hideCards (items) {
        items.forEach(function (item) {
            const title = item.querySelector('.ContentItem-title').innerHTML;
            if (item.classList.contains('TopstoryItem--advertCard') || /余生请多指教|肖战/.test(title)) {
                item.parentNode.removeChild(item);
            }
        });
    }

    function callback (mutationList, observer) {
        mutationList.forEach((mutation) => {
            if (mutation.type === 'childList') {
                if (mutation.addedNodes.length) {
                    hideCards(mutation.addedNodes);
                }
            }
        });
    }

    hideCards(document.querySelectorAll('#TopstoryContent .TopstoryItem'));

    var targetNode = document.querySelector('#TopstoryContent .TopstoryItem').parentNode;
    var observerOptions = {
        childList: true
    }
    var observer = new MutationObserver(callback);
    observer.observe(targetNode, observerOptions);

})();