Control a LumeCubeAir from Python via BLE + bluepy.

lumeCube.py

from bluepy import btle
import struct


class LumeCube:
    def __init__(self, mac):
        self.mac = mac
        self.SERVICE_UUID = "33826A4C-486A-11E4-A545-022807469BF0"
        self.LIGHT_CHARACTERISTIC = "33826A4D-486A-11E4-A545-022807469BF0"
        self.LIGHT_ON = struct.pack('>L', 0xFCA16400)
        self.LIGHT_OFF = struct.pack('>L', 0xFCA00000)

    def on(self):
        self._cube = btle.Peripheral(self.mac, addrType=btle.ADDR_TYPE_RANDOM)
        service = self._cube.getServiceByUUID(self.SERVICE_UUID)
        self._ch = service.getCharacteristics(self.LIGHT_CHARACTERISTIC)[0]
        self._ch.write(self.LIGHT_ON)

    def off(self):
        self._ch.write(self.LIGHT_OFF)
        self._cube.disconnect()