app.wsgi

import sys
sys.path.append(r"C:\webp")
from hello import app as application

hello.py

from flask import Flask
app = Flask(__name__)

@app.route("/")
def hello():
    return "Hello World!"

if __name__ == "__main__":
    app.run()

httpd.conf

<VirtualHost *>
    ServerName example.com

    WSGIScriptAlias / "C:\webp\app.wsgi"

    <Directory "C:\webp">
        Order deny,allow
        Allow from all
    </Directory>
</VirtualHost>