combo_plot.py

import ipywidgets as widgets

class SelectMultipleInteract(widgets.HBox):
    def __init__(self, combos, **plot_kwargs):
        self.W1 = widgets.SelectMultiple(
            options={str(x): x for x in combos},
            description="Combinations",
            disabled=False,
        )

        self.selectors = [self.W1]
        self.plot_kwargs = plot_kwargs
        super().__init__(children=self.selectors)
        self._set_observes()
        self._out = widgets.Output()
        display(self._out)

    def _set_observes(self):
        for widg in self.selectors:
            widg.observe(self._observed_function, names="value")

    def _observed_function(self, widg):
        with self._out:
            self._out.clear_output()
            for widg in self.selectors:
                plot(combos=widg.get_interact_value(), **self.plot_kwargs)


SelectMultipleInteract(
    combos,
    xy=xy,
    figsize=(9, 3),
)