Python List Comprehension: Consonants in a string

consonants.py

'''
Create a list of all the consonants in the string "Yellow Yaks like yelling and yawning and yesturday they yodled while eating yuky yams"
'''
sentence = "Yellow Yaks like yelling and yawning and yesturday they yodled while eating yuky yams"

result = [letter for letter in sentence if letter not in 'a,e,i,o,u, " "']

vowels_space = ['a', 'e', 'i', 'o', 'u', ' ']
sentence = 'Yellow Yaks like yelling and yawning and yesturday they yodled while eating yuky yams'
my_list = [letter for letter in sentence.lower() if letter not in vowels_space]