My Drupal 6/7 nginx site configuration file.

gistfile1.txt

# Drupal 6 NGINX Configuration File
        
        # Enable www.mysite.com or mysite.com to be served
        server {
                server_name www.mysite.com;
                rewrite ^/(.*) $scheme://mysite.com/$1 permanent;
        }
        server {
                server_name mysite.com;
                access_log /var/log/nginx/mysite.com-access.log;
                error_log /var/log/nginx/mysite.com-error.log;
                root /usr/share/nginx/html/mysite.com; ## <-- Your only path reference.
        
                location = /favicon.ico {
                        log_not_found off;
                        access_log off;
                }
         
                location = /robots.txt {
                        allow all;
                        log_not_found off;
                        access_log off;
                }
         
                # This matters if you use drush
                location = /backup {
                        deny all;
                }
         
                # Very rarely should these ever be accessed outside of your lan
                #location ~* \.(txt|log)$ {
                location ~* \.log$ {
                        allow 127.0.0.1;
                        deny all;
                }
         
                location ~ \..*/.*\.php$ {
                        return 403;
                }
         
                location / {
                        # This is cool because no php is touched for static content
                        try_files $uri @rewrite;
                }
         
                location @rewrite {
                        # Some modules enforce no slash (/) at the end of the URL
                        # Else this rewrite block wouldn't be needed (GlobalRedirect)
                        rewrite ^/(.*)$ /index.php?q=$1;
                }
         
                # This is using spawn-fcgi to process .php files
                location ~ \.php$ {
                        fastcgi_split_path_info ^(.+\.php)(/.+)$;
                        #NOTE: You should have "cgi.fix_pathinfo = 0;" in php.ini
                        include fastcgi_params;
                        fastcgi_param SCRIPT_FILENAME $document_root$fastcgi_script_name;
                        fastcgi_intercept_errors on;
                        fastcgi_pass unix:/var/run/php-fcgi.sock;
                }
        
                # Fix imagecache locations
                location ~* /files/imagecache/ {
                        access_log off;
                        try_files $uri @mysite; #imagecache support - now it works
                        rewrite ^/(.*)$ /index.php?q=$1 last;
        
                }
        
        
                # Catch image styles for D7 too.
                location ~ ^/sites/.*/files/styles/ {
                        try_files $uri @rewrite;
                }
         
                location ~* ^.+\.(js|css|png|jpg|jpeg|gif|ico)$ {
                        expires max;
                        log_not_found off;
                }
        }