Opening some .acsm files (e.g. those from archive.org) with Adobe Digital Editions will show the following error message: E_ADEPT_DOCUMENT_TOO_SHORT
Uncertain. Some have theorized it's because Adobe Digital Editions 2.0.1 requires .NET 3.5, which does not support TLS 1.2 out of the box.
There is a Windows patch to add TLS 1.2 support to .NET 3.5.1: https://support.microsoft.com/en-us/topic/support-for-tls-system-default-versions-included-in-the-net-framework-3-5-1-on-windows-7-sp1-and-server-2008-r2-sp1-5ef38dda-8e6c-65dc-c395-62d2df58715a
However this cannot be installed in Wine
On a Windows 7 VM, install the .NET 3.5.1 TLS 1.2 patch and Adobe Digital Editions 2.0.1.
PSA: The Windows 7 VM needs the TLS patch or be fully-updated, otherwise it will also face this error.